Rank | Gene Set | Z-score |
---|---|---|
1 | * nuclear pore complex assembly (GO:0051292) | 5.74800264 |
2 | * nuclear pore organization (GO:0006999) | 5.50542396 |
3 | mitotic sister chromatid cohesion (GO:0007064) | 5.00025012 |
4 | DNA unwinding involved in DNA replication (GO:0006268) | 4.21754357 |
5 | * pore complex assembly (GO:0046931) | 4.19428980 |
6 | protein localization to kinetochore (GO:0034501) | 4.14791162 |
7 | pre-miRNA processing (GO:0031054) | 4.09270991 |
8 | * mitotic nuclear envelope disassembly (GO:0007077) | 4.04695558 |
9 | regulation of histone H3-K9 methylation (GO:0051570) | 3.95483370 |
10 | mitotic chromosome condensation (GO:0007076) | 3.89934524 |
11 | negative regulation of histone methylation (GO:0031061) | 3.85158838 |
12 | heterochromatin organization (GO:0070828) | 3.83655874 |
13 | * nuclear envelope disassembly (GO:0051081) | 3.82305509 |
14 | * membrane disassembly (GO:0030397) | 3.82305509 |
15 | protein localization to chromosome, centromeric region (GO:0071459) | 3.80396486 |
16 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.66912114 |
17 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.66912114 |
18 | regulation of histone H3-K27 methylation (GO:0061085) | 3.65058285 |
19 | dosage compensation (GO:0007549) | 3.63266706 |
20 | DNA duplex unwinding (GO:0032508) | 3.58039823 |
21 | protein export from nucleus (GO:0006611) | 3.56861902 |
22 | DNA geometric change (GO:0032392) | 3.56748089 |
23 | DNA synthesis involved in DNA repair (GO:0000731) | 3.51922543 |
24 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.48152763 |
25 | sister chromatid segregation (GO:0000819) | 3.46067969 |
26 | monoubiquitinated protein deubiquitination (GO:0035520) | 3.45197333 |
27 | chromatin assembly (GO:0031497) | 3.42544038 |
28 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 3.40142565 |
29 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 3.40142565 |
30 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 3.40142565 |
31 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 3.38596397 |
32 | cellular protein complex localization (GO:0034629) | 3.36991182 |
33 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.34833352 |
34 | * regulation of nucleobase-containing compound transport (GO:0032239) | 3.33901044 |
35 | regulation of sister chromatid cohesion (GO:0007063) | 3.29348273 |
36 | positive regulation of chromosome segregation (GO:0051984) | 3.27235660 |
37 | RNA stabilization (GO:0043489) | 3.22974499 |
38 | mRNA stabilization (GO:0048255) | 3.22974499 |
39 | regulation of centriole replication (GO:0046599) | 3.21755179 |
40 | * regulation of RNA export from nucleus (GO:0046831) | 3.21472431 |
41 | mitotic sister chromatid segregation (GO:0000070) | 3.21331215 |
42 | protein complex localization (GO:0031503) | 3.20918853 |
43 | DNA replication initiation (GO:0006270) | 3.20878001 |
44 | regulation of spindle organization (GO:0090224) | 3.20696946 |
45 | histone H2A monoubiquitination (GO:0035518) | 3.17022141 |
46 | gene silencing by RNA (GO:0031047) | 3.16178409 |
47 | histone H3-K36 demethylation (GO:0070544) | 3.15481460 |
48 | formation of translation preinitiation complex (GO:0001731) | 3.14524032 |
49 | kinetochore organization (GO:0051383) | 3.14038187 |
50 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.13981193 |
51 | mitotic metaphase plate congression (GO:0007080) | 3.13094691 |
52 | ribosome assembly (GO:0042255) | 3.08505431 |
53 | DNA conformation change (GO:0071103) | 3.07650828 |
54 | chromatin assembly or disassembly (GO:0006333) | 3.05122107 |
55 | chromosome condensation (GO:0030261) | 3.04777984 |
56 | translesion synthesis (GO:0019985) | 3.03936685 |
57 | regulation of histone methylation (GO:0031060) | 3.03907859 |
58 | NLS-bearing protein import into nucleus (GO:0006607) | 3.02183211 |
59 | regulation of mitotic spindle organization (GO:0060236) | 3.02108323 |
60 | meiotic chromosome segregation (GO:0045132) | 3.01994670 |
61 | negative regulation of DNA repair (GO:0045738) | 3.01697652 |
62 | IMP biosynthetic process (GO:0006188) | 3.01550791 |
63 | telomere maintenance via recombination (GO:0000722) | 3.00593545 |
64 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.00358292 |
65 | regulation of histone H3-K4 methylation (GO:0051569) | 3.00348375 |
66 | regulation of DNA endoreduplication (GO:0032875) | 2.97310779 |
67 | protein localization to chromosome (GO:0034502) | 2.97101652 |
68 | * nuclear envelope organization (GO:0006998) | 2.96390647 |
69 | metaphase plate congression (GO:0051310) | 2.95679718 |
70 | mitotic recombination (GO:0006312) | 2.95292951 |
71 | sister chromatid cohesion (GO:0007062) | 2.92773433 |
72 | embryonic process involved in female pregnancy (GO:0060136) | 2.91923255 |
73 | glucocorticoid receptor signaling pathway (GO:0042921) | 2.91559991 |
74 | regulation of translational termination (GO:0006449) | 2.90390468 |
75 | DNA packaging (GO:0006323) | 2.89392421 |
76 | attachment of spindle microtubules to kinetochore (GO:0008608) | 2.86786386 |
77 | chromosome segregation (GO:0007059) | 2.85733301 |
78 | regulation of DNA damage checkpoint (GO:2000001) | 2.84406880 |
79 | non-recombinational repair (GO:0000726) | 2.83265560 |
80 | double-strand break repair via nonhomologous end joining (GO:0006303) | 2.83265560 |
81 | regulation of centrosome cycle (GO:0046605) | 2.80373346 |
82 | regulation of NFAT protein import into nucleus (GO:0051532) | 2.80262771 |
83 | gene silencing (GO:0016458) | 2.79951881 |
84 | regulation of posttranscriptional gene silencing (GO:0060147) | 2.79607969 |
85 | regulation of gene silencing by miRNA (GO:0060964) | 2.79607969 |
86 | regulation of gene silencing by RNA (GO:0060966) | 2.79607969 |
87 | regulation of chromatin binding (GO:0035561) | 2.78233143 |
88 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 2.77931982 |
89 | DNA strand elongation involved in DNA replication (GO:0006271) | 2.77506541 |
90 | negative regulation of histone modification (GO:0031057) | 2.76811545 |
91 | * mRNA transport (GO:0051028) | 2.76289995 |
92 | regulation of mRNA stability (GO:0043488) | 2.74252263 |
93 | histone mRNA catabolic process (GO:0071044) | 2.73449658 |
94 | regulation of translational fidelity (GO:0006450) | 2.73198790 |
95 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.73160523 |
96 | DNA replication-independent nucleosome organization (GO:0034724) | 2.73160523 |
97 | IMP metabolic process (GO:0046040) | 2.72657417 |
98 | regulation of chromosome segregation (GO:0051983) | 2.72110720 |
99 | negative regulation of mRNA processing (GO:0050686) | 2.71982593 |
100 | alternative mRNA splicing, via spliceosome (GO:0000380) | 2.68194201 |
101 | peptidyl-lysine dimethylation (GO:0018027) | 2.68166697 |
102 | DNA topological change (GO:0006265) | 2.68129145 |
103 | histone phosphorylation (GO:0016572) | 2.67895218 |
104 | V(D)J recombination (GO:0033151) | 2.65576079 |
105 | histone H2B ubiquitination (GO:0033523) | 2.65482459 |
106 | negative regulation of RNA splicing (GO:0033119) | 2.65334549 |
107 | DNA replication checkpoint (GO:0000076) | 2.65108654 |
108 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 2.64664258 |
109 | negative regulation of chromosome segregation (GO:0051985) | 2.64003306 |
110 | establishment of chromosome localization (GO:0051303) | 2.63950277 |
111 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 2.63916657 |
112 | negative regulation of chromatin modification (GO:1903309) | 2.63290970 |
113 | histone lysine demethylation (GO:0070076) | 2.62762069 |
114 | ATP-dependent chromatin remodeling (GO:0043044) | 2.62743059 |
115 | positive regulation of cell cycle checkpoint (GO:1901978) | 2.62695807 |
116 | DNA strand elongation (GO:0022616) | 2.61924209 |
117 | cytoplasmic mRNA processing body assembly (GO:0033962) | 2.61698423 |
118 | regulation of helicase activity (GO:0051095) | 2.61185855 |
119 | positive regulation of DNA-dependent DNA replication (GO:2000105) | 2.60725013 |
120 | regulation of RNA stability (GO:0043487) | 2.60595613 |
121 | protein K6-linked ubiquitination (GO:0085020) | 2.60140439 |
122 | chromatin remodeling at centromere (GO:0031055) | 2.59580537 |
123 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 2.59540086 |
124 | nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289) | 2.58428774 |
125 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 2.56212551 |
126 | histone exchange (GO:0043486) | 2.55759431 |
127 | * nucleic acid transport (GO:0050657) | 2.54312199 |
128 | * RNA transport (GO:0050658) | 2.54312199 |
129 | * establishment of RNA localization (GO:0051236) | 2.54312199 |
130 | regulation of centrosome duplication (GO:0010824) | 2.53425183 |
131 | negative regulation of mRNA metabolic process (GO:1903312) | 2.53343633 |
132 | microtubule cytoskeleton organization involved in mitosis (GO:1902850) | 2.52648322 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 5.39735428 |
2 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 4.07472191 |
3 | * E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.97178778 |
4 | * FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.00354199 |
5 | MYC_22102868_ChIP-Seq_BL_Human | 2.92536099 |
6 | * MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.86205209 |
7 | * NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.69263777 |
8 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.66692868 |
9 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.57601933 |
10 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.48263133 |
11 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.35904252 |
12 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.30477617 |
13 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.29708869 |
14 | * E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.28100450 |
15 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.22801875 |
16 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.18649414 |
17 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.18421203 |
18 | E2F7_22180533_ChIP-Seq_HELA_Human | 10.3243235 |
19 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.91992657 |
20 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.84583012 |
21 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.82522683 |
22 | * PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.71484499 |
23 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.71380993 |
24 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.66260045 |
25 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.63719605 |
26 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.63696609 |
27 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.60492517 |
28 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.57287965 |
29 | * TCF7_22412390_ChIP-Seq_EML_Mouse | 1.53595551 |
30 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.49055449 |
31 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.48883296 |
32 | GATA1_22025678_ChIP-Seq_K562_Human | 1.47885673 |
33 | * XRN2_22483619_ChIP-Seq_HELA_Human | 1.46049994 |
34 | MYB_26560356_Chip-Seq_TH1_Human | 1.44543517 |
35 | MYB_26560356_Chip-Seq_TH2_Human | 1.40800974 |
36 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.38115466 |
37 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.37850190 |
38 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.37721442 |
39 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.37162831 |
40 | * STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.36782116 |
41 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.34624001 |
42 | MAF_26560356_Chip-Seq_TH1_Human | 1.33186435 |
43 | * UTX_26944678_Chip-Seq_JUKART_Human | 1.32421968 |
44 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.32221873 |
45 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.31596644 |
46 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.31113402 |
47 | * CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.28526990 |
48 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.27859159 |
49 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.26152005 |
50 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.24813401 |
51 | * FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.23680125 |
52 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.23350300 |
53 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.22314090 |
54 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.21401900 |
55 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.20729406 |
56 | * CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.18283214 |
57 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.17784194 |
58 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.17614873 |
59 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.17563444 |
60 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.17548833 |
61 | * STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.17178831 |
62 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.15230642 |
63 | * THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.14455309 |
64 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.13842651 |
65 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.13773628 |
66 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.12515774 |
67 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.10642641 |
68 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.09660355 |
69 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.09294602 |
70 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.08570469 |
71 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.08452774 |
72 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.08225885 |
73 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 1.07245905 |
74 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.06856666 |
75 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.06814180 |
76 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.06196786 |
77 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.05737282 |
78 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.05732272 |
79 | * TTF2_22483619_ChIP-Seq_HELA_Human | 1.05480530 |
80 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.03837005 |
81 | * FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.01149528 |
82 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.00489306 |
83 | * SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 0.98901593 |
84 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 0.97146210 |
85 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.97028353 |
86 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.96879484 |
87 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.96630614 |
88 | * EST1_17652178_ChIP-ChIP_JURKAT_Human | 0.96574463 |
89 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 0.96536478 |
90 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.96499528 |
91 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.95272321 |
92 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 0.94975040 |
93 | CHD1_26751641_Chip-Seq_LNCaP_Human | 0.94182999 |
94 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 0.94123991 |
95 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.93943936 |
96 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.93934732 |
97 | * TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.93614031 |
98 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.93598309 |
99 | * HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.93451954 |
100 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 0.93239707 |
101 | * NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.93109195 |
102 | * PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.93106885 |
103 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 0.92862920 |
104 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.92862920 |
105 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 0.92862920 |
106 | * STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.92244220 |
107 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.91694955 |
108 | * CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.90523622 |
109 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 0.89180887 |
110 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 0.88383389 |
111 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 0.87755704 |
112 | * SPI1_23547873_ChIP-Seq_NB4_Human | 0.87438092 |
113 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 0.87120708 |
114 | SCL_19346495_ChIP-Seq_HPC-7_Human | 0.86619059 |
115 | * TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.84951311 |
116 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 0.84757334 |
117 | MAF_26560356_Chip-Seq_TH2_Human | 0.84545802 |
118 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.84284904 |
119 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 0.84248833 |
120 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.84027749 |
121 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 0.83477526 |
122 | * GABP_19822575_ChIP-Seq_HepG2_Human | 0.81808564 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0010094_abnormal_chromosome_stability | 3.53326307 |
2 | MP0008057_abnormal_DNA_replication | 3.52496670 |
3 | MP0003111_abnormal_nucleus_morphology | 3.17305388 |
4 | MP0010352_gastrointestinal_tract_polyps | 3.15199893 |
5 | MP0003077_abnormal_cell_cycle | 3.03119777 |
6 | MP0003693_abnormal_embryo_hatching | 3.02542648 |
7 | MP0004957_abnormal_blastocyst_morpholog | 2.91115844 |
8 | MP0010307_abnormal_tumor_latency | 2.62726817 |
9 | MP0008877_abnormal_DNA_methylation | 2.51179450 |
10 | MP0005076_abnormal_cell_differentiation | 2.50089216 |
11 | MP0005451_abnormal_body_composition | 2.30119239 |
12 | MP0002396_abnormal_hematopoietic_system | 2.29795239 |
13 | MP0004808_abnormal_hematopoietic_stem | 2.18227645 |
14 | MP0001730_embryonic_growth_arrest | 2.14684198 |
15 | MP0003705_abnormal_hypodermis_morpholog | 2.13481183 |
16 | MP0008007_abnormal_cellular_replicative | 2.13067082 |
17 | MP0000350_abnormal_cell_proliferation | 2.10821232 |
18 | MP0008058_abnormal_DNA_repair | 2.10017627 |
19 | MP0003763_abnormal_thymus_physiology | 1.91079544 |
20 | MP0003123_paternal_imprinting | 1.87669634 |
21 | MP0004197_abnormal_fetal_growth/weight/ | 1.82237065 |
22 | MP0005380_embryogenesis_phenotype | 1.78386298 |
23 | MP0001672_abnormal_embryogenesis/_devel | 1.78386298 |
24 | MP0003984_embryonic_growth_retardation | 1.69071291 |
25 | MP0002084_abnormal_developmental_patter | 1.68943958 |
26 | MP0002086_abnormal_extraembryonic_tissu | 1.68115490 |
27 | MP0002088_abnormal_embryonic_growth/wei | 1.67657312 |
28 | MP0009697_abnormal_copulation | 1.65726194 |
29 | MP0001697_abnormal_embryo_size | 1.65721321 |
30 | MP0004233_abnormal_muscle_weight | 1.65438941 |
31 | MP0003300_gastrointestinal_ulcer | 1.60448447 |
32 | MP0003121_genomic_imprinting | 1.58047283 |
33 | MP0008932_abnormal_embryonic_tissue | 1.53437705 |
34 | MP0000703_abnormal_thymus_morphology | 1.51009028 |
35 | MP0002085_abnormal_embryonic_tissue | 1.50943582 |
36 | MP0009278_abnormal_bone_marrow | 1.49424956 |
37 | MP0003890_abnormal_embryonic-extraembry | 1.47027011 |
38 | MP0003656_abnormal_erythrocyte_physiolo | 1.45439113 |
39 | MP0001545_abnormal_hematopoietic_system | 1.42583412 |
40 | MP0005397_hematopoietic_system_phenotyp | 1.42583412 |
41 | MP0002398_abnormal_bone_marrow | 1.41441600 |
42 | MP0000490_abnormal_crypts_of | 1.39020594 |
43 | MP0010234_abnormal_vibrissa_follicle | 1.38947084 |
44 | MP0002080_prenatal_lethality | 1.38693433 |
45 | MP0003566_abnormal_cell_adhesion | 1.31649067 |
46 | MP0002166_altered_tumor_susceptibility | 1.30878588 |
47 | MP0003221_abnormal_cardiomyocyte_apopto | 1.30687712 |
48 | MP0000569_abnormal_digit_pigmentation | 1.29686215 |
49 | MP0003567_abnormal_fetal_cardiomyocyte | 1.29108628 |
50 | MP0002019_abnormal_tumor_incidence | 1.25627537 |
51 | MP0000733_abnormal_muscle_development | 1.23787908 |
52 | MP0005023_abnormal_wound_healing | 1.23414472 |
53 | MP0003786_premature_aging | 1.22955321 |
54 | MP0003303_peritoneal_inflammation | 1.22015527 |
55 | MP0001929_abnormal_gametogenesis | 1.19172473 |
56 | MP0002722_abnormal_immune_system | 1.18957248 |
57 | MP0001293_anophthalmia | 1.18928906 |
58 | MP0002210_abnormal_sex_determination | 1.18627969 |
59 | MP0002006_tumorigenesis | 1.15098758 |
60 | MP0000313_abnormal_cell_death | 1.14843126 |
61 | MP0000689_abnormal_spleen_morphology | 1.13090424 |
62 | MP0002877_abnormal_melanocyte_morpholog | 1.12478459 |
63 | MP0001800_abnormal_humoral_immune | 1.11483627 |
64 | MP0009053_abnormal_anal_canal | 1.11171172 |
65 | MP0001915_intracranial_hemorrhage | 1.09966113 |
66 | MP0003453_abnormal_keratinocyte_physiol | 1.09190253 |
67 | MP0000685_abnormal_immune_system | 1.08955022 |
68 | MP0001661_extended_life_span | 1.06356262 |
69 | MP0005409_darkened_coat_color | 1.05779841 |
70 | MP0001145_abnormal_male_reproductive | 1.04465729 |
71 | MP0002796_impaired_skin_barrier | 1.02407658 |
72 | MP0009703_decreased_birth_body | 1.00679422 |
73 | MP0000537_abnormal_urethra_morphology | 1.00602030 |
74 | MP0003787_abnormal_imprinting | 0.98553613 |
75 | MP0009333_abnormal_splenocyte_physiolog | 0.97463883 |
76 | MP0005384_cellular_phenotype | 0.96895011 |
77 | MP0002405_respiratory_system_inflammati | 0.95856652 |
78 | MP0000716_abnormal_immune_system | 0.95681946 |
79 | MP0003941_abnormal_skin_development | 0.95666345 |
80 | MP0002925_abnormal_cardiovascular_devel | 0.94261068 |
81 | MP0009672_abnormal_birth_weight | 0.94005660 |
82 | MP0002429_abnormal_blood_cell | 0.93938202 |
83 | MP0003943_abnormal_hepatobiliary_system | 0.92250410 |
84 | MP0001348_abnormal_lacrimal_gland | 0.91790435 |
85 | MP0002092_abnormal_eye_morphology | 0.91389868 |
86 | MP0001346_abnormal_lacrimal_gland | 0.91313667 |
87 | MP0005410_abnormal_fertilization | 0.90342109 |
88 | MP0003091_abnormal_cell_migration | 0.89820825 |
89 | MP0004185_abnormal_adipocyte_glucose | 0.89104242 |
90 | MP0000653_abnormal_sex_gland | 0.88569044 |
91 | MP0006054_spinal_hemorrhage | 0.87778731 |
92 | MP0002420_abnormal_adaptive_immunity | 0.87506825 |
93 | MP0005501_abnormal_skin_physiology | 0.86963213 |
94 | MP0002452_abnormal_antigen_presenting | 0.86928141 |
95 | MP0003448_altered_tumor_morphology | 0.85368345 |
96 | MP0001819_abnormal_immune_cell | 0.85016819 |
97 | MP0001849_ear_inflammation | 0.84543521 |
98 | MP0010630_abnormal_cardiac_muscle | 0.84052930 |
99 | MP0003115_abnormal_respiratory_system | 0.84042153 |
100 | MP0000428_abnormal_craniofacial_morphol | 0.83788950 |
101 | MP0004264_abnormal_extraembryonic_tissu | 0.80064070 |
102 | MP0000858_altered_metastatic_potential | 0.79546799 |
103 | MP0003119_abnormal_digestive_system | 0.78934468 |
104 | MP0002723_abnormal_immune_serum | 0.78485322 |
105 | MP0005621_abnormal_cell_physiology | 0.78087542 |
106 | MP0000432_abnormal_head_morphology | 0.77737206 |
107 | MP0001835_abnormal_antigen_presentation | 0.77678418 |
108 | MP0005666_abnormal_adipose_tissue | 0.75327948 |
109 | MP0003937_abnormal_limbs/digits/tail_de | 0.75011404 |
110 | MP0003935_abnormal_craniofacial_develop | 0.74757545 |
111 | MP0001216_abnormal_epidermal_layer | 0.74614157 |
112 | MP0005671_abnormal_response_to | 0.74536626 |
113 | MP0002697_abnormal_eye_size | 0.73509626 |
114 | MP0002060_abnormal_skin_morphology | 0.73117984 |
115 | MP0003436_decreased_susceptibility_to | 0.72961972 |
116 | MP0002009_preneoplasia | 0.72793031 |
117 | MP0003698_abnormal_male_reproductive | 0.72593612 |
118 | MP0001873_stomach_inflammation | 0.72406549 |
119 | MP0003718_maternal_effect | 0.72131160 |
120 | MP0004947_skin_inflammation | 0.71990328 |
121 | MP0005623_abnormal_meninges_morphology | 0.71332843 |
122 | MP0000627_abnormal_mammary_gland | 0.69876731 |
123 | MP0003699_abnormal_female_reproductive | 0.69482193 |
124 | MP0000003_abnormal_adipose_tissue | 0.68859747 |
125 | MP0003950_abnormal_plasma_membrane | 0.66166267 |
126 | MP0008260_abnormal_autophagy | 0.66145943 |
127 | MP0008995_early_reproductive_senescence | 0.63832129 |
128 | MP0001853_heart_inflammation | 0.63182998 |
129 | MP0000377_abnormal_hair_follicle | 0.62575227 |
130 | MP0000358_abnormal_cell_content/ | 0.61385682 |
131 | MP0009931_abnormal_skin_appearance | 0.60074087 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Volvulus (HP:0002580) | 3.28377150 |
2 | Abnormality of the fingertips (HP:0001211) | 3.27459922 |
3 | Ependymoma (HP:0002888) | 3.03653021 |
4 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.91131385 |
5 | Medulloblastoma (HP:0002885) | 2.80705574 |
6 | Ankyloglossia (HP:0010296) | 2.76158659 |
7 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.71883220 |
8 | Short 4th metacarpal (HP:0010044) | 2.71883220 |
9 | Embryonal renal neoplasm (HP:0011794) | 2.66998671 |
10 | Dysmetric saccades (HP:0000641) | 2.65101046 |
11 | Deviation of the thumb (HP:0009603) | 2.59444414 |
12 | Colon cancer (HP:0003003) | 2.53761591 |
13 | Basal cell carcinoma (HP:0002671) | 2.52149945 |
14 | Proximal placement of thumb (HP:0009623) | 2.50407815 |
15 | Increased nuchal translucency (HP:0010880) | 2.50027481 |
16 | Heterotopia (HP:0002282) | 2.49662560 |
17 | Selective tooth agenesis (HP:0001592) | 2.48891924 |
18 | Chromsome breakage (HP:0040012) | 2.47844334 |
19 | Prominent nose (HP:0000448) | 2.44793556 |
20 | Rhabdomyosarcoma (HP:0002859) | 2.43486900 |
21 | Birth length less than 3rd percentile (HP:0003561) | 2.41549833 |
22 | Abnormality of the astrocytes (HP:0100707) | 2.40040123 |
23 | Astrocytoma (HP:0009592) | 2.40040123 |
24 | Long eyelashes (HP:0000527) | 2.38210345 |
25 | Abnormality of chromosome stability (HP:0003220) | 2.37101905 |
26 | Increased density of long bones (HP:0006392) | 2.32961835 |
27 | Abnormality of oral frenula (HP:0000190) | 2.32563599 |
28 | Progressive external ophthalmoplegia (HP:0000590) | 2.31917884 |
29 | Asymmetry of the thorax (HP:0001555) | 2.28896284 |
30 | T lymphocytopenia (HP:0005403) | 2.28003918 |
31 | Ectopic kidney (HP:0000086) | 2.27021052 |
32 | Biliary tract neoplasm (HP:0100574) | 2.26743091 |
33 | Progressive muscle weakness (HP:0003323) | 2.24627613 |
34 | Papillary thyroid carcinoma (HP:0002895) | 2.24522346 |
35 | Acute myeloid leukemia (HP:0004808) | 2.23445145 |
36 | Neoplasm of the oral cavity (HP:0100649) | 2.22924511 |
37 | Facial hemangioma (HP:0000329) | 2.21823757 |
38 | Abnormality of chromosome segregation (HP:0002916) | 2.19781587 |
39 | High pitched voice (HP:0001620) | 2.16820114 |
40 | Uterine leiomyosarcoma (HP:0002891) | 2.15619755 |
41 | Leiomyosarcoma (HP:0100243) | 2.15619755 |
42 | Abnormality of the preputium (HP:0100587) | 2.15395460 |
43 | Absent frontal sinuses (HP:0002688) | 2.14055286 |
44 | Impulsivity (HP:0100710) | 2.12712237 |
45 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.12094322 |
46 | Termporal pattern (HP:0011008) | 2.11754365 |
47 | Insidious onset (HP:0003587) | 2.11754365 |
48 | Sandal gap (HP:0001852) | 2.11630375 |
49 | Glioma (HP:0009733) | 2.11474269 |
50 | Abnormality of T cell number (HP:0011839) | 2.11430945 |
51 | Neoplasm of striated muscle (HP:0009728) | 2.10792712 |
52 | Relative macrocephaly (HP:0004482) | 2.09178663 |
53 | Malignant gastrointestinal tract tumors (HP:0006749) | 2.08665764 |
54 | Gastrointestinal carcinoma (HP:0002672) | 2.08665764 |
55 | Truncal obesity (HP:0001956) | 2.08344035 |
56 | Acute lymphatic leukemia (HP:0006721) | 2.06793156 |
57 | Myelodysplasia (HP:0002863) | 2.05461477 |
58 | Deep palmar crease (HP:0006191) | 2.05095670 |
59 | Agnosia (HP:0010524) | 2.04841320 |
60 | Recurrent bronchitis (HP:0002837) | 2.04549593 |
61 | Cortical dysplasia (HP:0002539) | 2.04465807 |
62 | Obsessive-compulsive behavior (HP:0000722) | 2.02958329 |
63 | Abnormality of the labia minora (HP:0012880) | 2.02784382 |
64 | Skull defect (HP:0001362) | 2.01243829 |
65 | Septate vagina (HP:0001153) | 1.98716534 |
66 | Broad palm (HP:0001169) | 1.96079315 |
67 | Subacute progressive viral hepatitis (HP:0006572) | 1.95625436 |
68 | Amaurosis fugax (HP:0100576) | 1.94835730 |
69 | Transitional cell carcinoma of the bladder (HP:0006740) | 1.94255737 |
70 | IgA deficiency (HP:0002720) | 1.93299239 |
71 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.92062674 |
72 | Cafe-au-lait spot (HP:0000957) | 1.90573152 |
73 | Abnormal foot bone ossification (HP:0010675) | 1.89598067 |
74 | Cutaneous melanoma (HP:0012056) | 1.89043312 |
75 | Pelvic girdle muscle weakness (HP:0003749) | 1.88878140 |
76 | Abnormality of the 4th metacarpal (HP:0010012) | 1.88858608 |
77 | Cutis marmorata (HP:0000965) | 1.88320152 |
78 | Deep philtrum (HP:0002002) | 1.87224042 |
79 | Bladder neoplasm (HP:0009725) | 1.86023628 |
80 | Bladder carcinoma (HP:0002862) | 1.86023628 |
81 | Degeneration of anterior horn cells (HP:0002398) | 1.85734118 |
82 | Abnormality of the anterior horn cell (HP:0006802) | 1.85734118 |
83 | Limited elbow extension (HP:0001377) | 1.85265847 |
84 | Low anterior hairline (HP:0000294) | 1.85152800 |
85 | Fatigue (HP:0012378) | 1.84814794 |
86 | Orthostatic hypotension (HP:0001278) | 1.83601802 |
87 | Atresia of the external auditory canal (HP:0000413) | 1.83201154 |
88 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.81813397 |
89 | Missing ribs (HP:0000921) | 1.81639179 |
90 | Viral hepatitis (HP:0006562) | 1.81569585 |
91 | Nasal polyposis (HP:0100582) | 1.81428085 |
92 | High anterior hairline (HP:0009890) | 1.81408041 |
93 | Embryonal neoplasm (HP:0002898) | 1.80686105 |
94 | Cerebral aneurysm (HP:0004944) | 1.79683329 |
95 | Trigonocephaly (HP:0000243) | 1.79001656 |
96 | Hematochezia (HP:0002573) | 1.78104890 |
97 | Supernumerary ribs (HP:0005815) | 1.77966811 |
98 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 1.77776980 |
99 | Dislocated radial head (HP:0003083) | 1.77325269 |
100 | 11 pairs of ribs (HP:0000878) | 1.76281353 |
101 | Urethral obstruction (HP:0000796) | 1.75569117 |
102 | Hereditary nonpolyposis colorectal carcinoma (HP:0006716) | 1.74903398 |
103 | Short middle phalanx of the 5th finger (HP:0004220) | 1.74816740 |
104 | Bicuspid aortic valve (HP:0001647) | 1.74378152 |
105 | Hyperacusis (HP:0010780) | 1.73999066 |
106 | Multiple enchondromatosis (HP:0005701) | 1.73864990 |
107 | Abnormality of the salivary glands (HP:0010286) | 1.73815440 |
108 | Broad thumb (HP:0011304) | 1.73774477 |
109 | Patellar aplasia (HP:0006443) | 1.73145042 |
110 | Insomnia (HP:0100785) | 1.72909731 |
111 | Skin tags (HP:0010609) | 1.72733405 |
112 | Reticulocytopenia (HP:0001896) | 1.72453181 |
113 | Neonatal hypoglycemia (HP:0001998) | 1.71927249 |
114 | Recurrent viral infections (HP:0004429) | 1.71407308 |
115 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.67869224 |
116 | Thrombocytosis (HP:0001894) | 1.66571258 |
117 | Bowel incontinence (HP:0002607) | 1.66525566 |
118 | Renal cell carcinoma (HP:0005584) | 1.65753409 |
119 | Narrow palate (HP:0000189) | 1.65675575 |
120 | Macroorchidism (HP:0000053) | 1.65015978 |
121 | Meckel diverticulum (HP:0002245) | 1.64495924 |
122 | Abnormality of the radial head (HP:0003995) | 1.63726342 |
123 | Capillary hemangiomas (HP:0005306) | 1.63679750 |
124 | Duodenal stenosis (HP:0100867) | 1.63589291 |
125 | Small intestinal stenosis (HP:0012848) | 1.63589291 |
126 | Sparse lateral eyebrow (HP:0005338) | 1.63536656 |
127 | Disproportionate tall stature (HP:0001519) | 1.63220620 |
128 | Choanal atresia (HP:0000453) | 1.63183076 |
129 | Abnormality of the phalanges of the hallux (HP:0010057) | 1.62390943 |
130 | Supernumerary bones of the axial skeleton (HP:0009144) | 1.61800425 |
131 | Abnormal number of incisors (HP:0011064) | 1.61574905 |
132 | Abnormal large intestine physiology (HP:0012700) | 1.61542467 |
133 | Ulnar bowing (HP:0003031) | 1.61538044 |
134 | Cubitus valgus (HP:0002967) | 1.61535830 |
135 | Persistence of primary teeth (HP:0006335) | 1.61507423 |
136 | Abnormality of the left ventricular outflow tract (HP:0011103) | 1.61277807 |
137 | Subaortic stenosis (HP:0001682) | 1.61277807 |
138 | Shallow orbits (HP:0000586) | 1.61257266 |
139 | Flat acetabular roof (HP:0003180) | 1.60654462 |
140 | Abnormality of the calcaneus (HP:0008364) | 1.60450876 |
141 | Rectal prolapse (HP:0002035) | 1.60146528 |
142 | Cone-shaped epiphyses of the phalanges of the hand (HP:0010230) | 1.59404129 |
143 | Squamous cell carcinoma (HP:0002860) | 1.58416411 |
144 | Overlapping toe (HP:0001845) | 1.57814250 |
145 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.57613432 |
146 | Abnormality of T cells (HP:0002843) | 1.57411140 |
147 | Syringomyelia (HP:0003396) | 1.56955577 |
148 | Spinal cord lesions (HP:0100561) | 1.56955577 |
149 | Abnormality of the carotid arteries (HP:0005344) | 1.56154220 |
150 | Blepharitis (HP:0000498) | 1.55737611 |
151 | Abnormality of the ileum (HP:0001549) | 1.55062601 |
152 | Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026) | 1.54786636 |
153 | Short 1st metacarpal (HP:0010034) | 1.54786636 |
Rank | Gene Set | Z-score |
---|---|---|
1 | CDK12 | 4.33600805 |
2 | CDC7 | 4.11206178 |
3 | SMG1 | 3.11421224 |
4 | EEF2K | 3.10893949 |
5 | NEK2 | 2.75853923 |
6 | PRPF4B | 2.61307005 |
7 | PKN2 | 2.28760959 |
8 | MAP3K10 | 2.28643966 |
9 | STK10 | 2.28401871 |
10 | WEE1 | 2.20666686 |
11 | MAP4K1 | 2.13831416 |
12 | BRD4 | 1.81614777 |
13 | TTK | 1.73556447 |
14 | LATS1 | 1.73312057 |
15 | RPS6KB2 | 1.71521139 |
16 | ACVR1B | 1.69768039 |
17 | CDK4 | 1.66496717 |
18 | RPS6KA4 | 1.62146486 |
19 | ATR | 1.57489577 |
20 | CDK6 | 1.55780719 |
21 | PASK | 1.53109192 |
22 | KSR2 | 1.51441675 |
23 | TSSK6 | 1.50752269 |
24 | STK3 | 1.49492480 |
25 | ALK | 1.37440508 |
26 | TGFBR1 | 1.36326580 |
27 | SCYL2 | 1.35583007 |
28 | * CHEK1 | 1.35409152 |
29 | MAP3K8 | 1.31573803 |
30 | SRPK1 | 1.29026422 |
31 | TRIB3 | 1.27246063 |
32 | CLK1 | 1.26717843 |
33 | JAK3 | 1.26530393 |
34 | EIF2AK3 | 1.24655558 |
35 | MAP3K14 | 1.23723015 |
36 | TTN | 1.23293286 |
37 | PIM1 | 1.23030077 |
38 | MKNK1 | 1.21821120 |
39 | CDK7 | 1.20255825 |
40 | AURKB | 1.19818339 |
41 | CHEK2 | 1.18144593 |
42 | MELK | 1.17804694 |
43 | MTOR | 1.17203234 |
44 | PLK1 | 1.16503219 |
45 | ATM | 1.15807553 |
46 | STK4 | 1.12445746 |
47 | FGFR3 | 1.10889121 |
48 | TAF1 | 1.10361304 |
49 | IRAK3 | 1.09190743 |
50 | LRRK2 | 1.06085996 |
51 | MAP3K2 | 1.00836106 |
52 | BRSK2 | 0.98899050 |
53 | MKNK2 | 0.98646956 |
54 | EIF2AK1 | 0.97561735 |
55 | PLK3 | 0.96940542 |
56 | PBK | 0.96522254 |
57 | PLK4 | 0.95090765 |
58 | FLT3 | 0.94391850 |
59 | TXK | 0.93589718 |
60 | ITK | 0.92733634 |
61 | PTK6 | 0.92200611 |
62 | EPHA2 | 0.91778612 |
63 | CDK9 | 0.91150974 |
64 | MAP3K13 | 0.90787680 |
65 | * CDK2 | 0.90533606 |
66 | LATS2 | 0.90283195 |
67 | DYRK3 | 0.88704984 |
68 | ZAP70 | 0.85242518 |
69 | WNK1 | 0.85198187 |
70 | NEK1 | 0.85172266 |
71 | TLK1 | 0.82545098 |
72 | RAF1 | 0.81832085 |
73 | RIPK1 | 0.81273496 |
74 | KSR1 | 0.80621290 |
75 | GRK6 | 0.80405842 |
76 | MAP2K3 | 0.80390569 |
77 | CAMK1D | 0.80144841 |
78 | BUB1 | 0.78730813 |
79 | ICK | 0.76735145 |
80 | FGFR4 | 0.76502484 |
81 | MARK3 | 0.75339399 |
82 | PAK4 | 0.74668523 |
83 | CHUK | 0.72950021 |
84 | BRAF | 0.72640551 |
85 | PDK4 | 0.71391007 |
86 | PDK3 | 0.71391007 |
87 | MAPK11 | 0.71263180 |
88 | PAK2 | 0.71155178 |
89 | FGFR1 | 0.69857040 |
90 | BRSK1 | 0.68118300 |
91 | PDGFRB | 0.67197934 |
92 | TYK2 | 0.66948957 |
93 | YES1 | 0.66408426 |
94 | CDK1 | 0.64610401 |
95 | PNCK | 0.64158146 |
96 | PDGFRA | 0.62814134 |
97 | NLK | 0.62232893 |
98 | CSNK1D | 0.61011504 |
99 | RIPK4 | 0.59220750 |
100 | BTK | 0.57844513 |
101 | CDK8 | 0.57544737 |
102 | EIF2AK2 | 0.54747673 |
103 | TESK1 | 0.54494612 |
104 | AURKA | 0.54373230 |
105 | RPS6KA5 | 0.53772427 |
106 | TRPM7 | 0.50291754 |
107 | STK24 | 0.49511193 |
108 | LCK | 0.49041441 |
109 | MST1R | 0.49033568 |
110 | PRKDC | 0.48989649 |
111 | MAP3K3 | 0.48503592 |
112 | TAOK2 | 0.48134979 |
113 | BMX | 0.46950972 |
114 | CSF1R | 0.45977300 |
115 | TYRO3 | 0.45925093 |
116 | CAMK1G | 0.45351660 |
117 | HCK | 0.45162020 |
118 | MAP3K9 | 0.44882272 |
119 | MAPK14 | 0.43599181 |
120 | NEK6 | 0.43158852 |
121 | SGK3 | 0.42956596 |
122 | MAP3K1 | 0.42469072 |
123 | MAPK10 | 0.42223767 |
124 | CSK | 0.41974756 |
125 | AKT3 | 0.41163059 |
126 | BMPR2 | 0.41103450 |
127 | SIK3 | 0.41016862 |
128 | TEC | 0.40515938 |
129 | DMPK | 0.40349773 |
130 | CSNK2A2 | 0.40146330 |
131 | RPS6KB1 | 0.39977597 |
132 | RET | 0.39915020 |
133 | NEK9 | 0.39690232 |
134 | NME2 | 0.38102039 |
135 | TGFBR2 | 0.37469309 |
136 | * MAPK1 | 0.37433384 |
137 | JAK1 | 0.36382920 |
138 | FGFR2 | 0.36124106 |
139 | SIK1 | 0.35894962 |
140 | CSNK1E | 0.35855032 |
141 | GSK3B | 0.34266432 |
142 | AKT2 | 0.34162178 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 3.09024535 |
2 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.68596370 |
3 | Mismatch repair_Homo sapiens_hsa03430 | 2.68244190 |
4 | * RNA transport_Homo sapiens_hsa03013 | 2.64407631 |
5 | Cell cycle_Homo sapiens_hsa04110 | 2.56317718 |
6 | Spliceosome_Homo sapiens_hsa03040 | 2.41733760 |
7 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.07991511 |
8 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 2.06260267 |
9 | Base excision repair_Homo sapiens_hsa03410 | 1.78594683 |
10 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.77720093 |
11 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.74360086 |
12 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.73032470 |
13 | Homologous recombination_Homo sapiens_hsa03440 | 1.69960480 |
14 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.64018674 |
15 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.63918027 |
16 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.60445990 |
17 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.59333769 |
18 | RNA degradation_Homo sapiens_hsa03018 | 1.58967685 |
19 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.58419353 |
20 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.50974242 |
21 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.43700479 |
22 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.42882798 |
23 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.36991275 |
24 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.35809245 |
25 | HTLV-I infection_Homo sapiens_hsa05166 | 1.35462997 |
26 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.34108455 |
27 | Basal transcription factors_Homo sapiens_hsa03022 | 1.28056644 |
28 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.26977687 |
29 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.25545268 |
30 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.24511361 |
31 | Measles_Homo sapiens_hsa05162 | 1.18868072 |
32 | Glioma_Homo sapiens_hsa05214 | 1.17843079 |
33 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.17161242 |
34 | Colorectal cancer_Homo sapiens_hsa05210 | 1.16366297 |
35 | Adherens junction_Homo sapiens_hsa04520 | 1.14442654 |
36 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.13839218 |
37 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.10726118 |
38 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.10059275 |
39 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.09369443 |
40 | Viral myocarditis_Homo sapiens_hsa05416 | 1.09179797 |
41 | Hepatitis B_Homo sapiens_hsa05161 | 1.05205992 |
42 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.01366998 |
43 | Thyroid cancer_Homo sapiens_hsa05216 | 1.00786874 |
44 | Lysine degradation_Homo sapiens_hsa00310 | 1.00430832 |
45 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.99370196 |
46 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.95474485 |
47 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.94926763 |
48 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.94321223 |
49 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.92940288 |
50 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.92892065 |
51 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.92177890 |
52 | Prostate cancer_Homo sapiens_hsa05215 | 0.89995647 |
53 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.88940331 |
54 | Leishmaniasis_Homo sapiens_hsa05140 | 0.88342837 |
55 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.85511531 |
56 | Apoptosis_Homo sapiens_hsa04210 | 0.85127017 |
57 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.83641520 |
58 | Influenza A_Homo sapiens_hsa05164 | 0.83040821 |
59 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.82959072 |
60 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.82929302 |
61 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.82870693 |
62 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.82726193 |
63 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.81454053 |
64 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.81062780 |
65 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.80634841 |
66 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.80548733 |
67 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.80194200 |
68 | Legionellosis_Homo sapiens_hsa05134 | 0.79892972 |
69 | RNA polymerase_Homo sapiens_hsa03020 | 0.79845863 |
70 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.79760491 |
71 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.79326021 |
72 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.78960391 |
73 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.77830879 |
74 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.77032301 |
75 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.76757204 |
76 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.76566279 |
77 | Ribosome_Homo sapiens_hsa03010 | 0.75742283 |
78 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.75247366 |
79 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.75223503 |
80 | Endometrial cancer_Homo sapiens_hsa05213 | 0.75000075 |
81 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.74418601 |
82 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.72937149 |
83 | Hepatitis C_Homo sapiens_hsa05160 | 0.72740454 |
84 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.70483060 |
85 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.70252841 |
86 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.67793511 |
87 | Pathways in cancer_Homo sapiens_hsa05200 | 0.67658927 |
88 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.67649233 |
89 | Alcoholism_Homo sapiens_hsa05034 | 0.67428348 |
90 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.67235661 |
91 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.65213377 |
92 | Shigellosis_Homo sapiens_hsa05131 | 0.63914180 |
93 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.62717823 |
94 | Melanoma_Homo sapiens_hsa05218 | 0.62200090 |
95 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.61517173 |
96 | Focal adhesion_Homo sapiens_hsa04510 | 0.60335768 |
97 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.59787943 |
98 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.59694010 |
99 | Platelet activation_Homo sapiens_hsa04611 | 0.59079502 |
100 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.58578361 |
101 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.57745726 |
102 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.56029015 |
103 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.55664659 |
104 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.53720324 |
105 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.52742517 |
106 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.50471471 |
107 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.50461106 |
108 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.49529564 |
109 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.49023427 |
110 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.48656198 |
111 | Bladder cancer_Homo sapiens_hsa05219 | 0.48365734 |
112 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.44972162 |
113 | Insulin resistance_Homo sapiens_hsa04931 | 0.44652321 |
114 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.44585327 |
115 | Allograft rejection_Homo sapiens_hsa05330 | 0.42085043 |
116 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.40912775 |
117 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.40210374 |
118 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.37817024 |