NUP188

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The nuclear pore complex (NPC) is found on the nuclear envelope and forms a gateway that regulates the flow of proteins and RNAs between the cytoplasm and nucleoplasm. The NPC is comprised of approximately 30 distinct proteins collectively known as nucleoporins. Nucleoporins are pore-complex-specific glycoproteins which often have cytoplasmically oriented O-linked N-acetylglucosamine residues and numerous repeats of the pentapeptide sequence XFXFG. However, the nucleoporin protein encoded by this gene does not contain the typical FG repeat sequences found in most vertebrate nucleoporins. This nucleoporin is thought to form part of the scaffold for the central channel of the nuclear pore. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)5.50276013
2nuclear pore organization (GO:0006999)5.42380285
3DNA unwinding involved in DNA replication (GO:0006268)5.00215403
4protein localization to kinetochore (GO:0034501)4.74079382
5DNA replication-dependent nucleosome organization (GO:0034723)4.39664903
6DNA replication-dependent nucleosome assembly (GO:0006335)4.39664903
7pre-miRNA processing (GO:0031054)4.33655265
8heterochromatin organization (GO:0070828)4.25021364
9protein localization to chromosome, centromeric region (GO:0071459)4.19833753
10pore complex assembly (GO:0046931)4.14224291
11* mitotic nuclear envelope disassembly (GO:0007077)4.12877812
12mitotic sister chromatid segregation (GO:0000070)3.99494860
13regulation of translational fidelity (GO:0006450)3.95996872
14sister chromatid segregation (GO:0000819)3.92097477
15DNA topological change (GO:0006265)3.88629799
16* nuclear envelope disassembly (GO:0051081)3.85612808
17* membrane disassembly (GO:0030397)3.85612808
18regulation of posttranscriptional gene silencing (GO:0060147)3.85180094
19regulation of gene silencing by miRNA (GO:0060964)3.85180094
20regulation of gene silencing by RNA (GO:0060966)3.85180094
21folic acid-containing compound biosynthetic process (GO:0009396)3.84670639
22DNA replication initiation (GO:0006270)3.83160464
23mitotic sister chromatid cohesion (GO:0007064)3.79837747
24regulation of histone H3-K9 methylation (GO:0051570)3.75549818
25COPI coating of Golgi vesicle (GO:0048205)3.75356751
26Golgi transport vesicle coating (GO:0048200)3.75356751
27DNA duplex unwinding (GO:0032508)3.73418289
28DNA geometric change (GO:0032392)3.72672447
29DNA strand elongation involved in DNA replication (GO:0006271)3.69796510
30mitotic chromosome condensation (GO:0007076)3.68390365
31regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.61588162
32IMP biosynthetic process (GO:0006188)3.52162913
33DNA strand elongation (GO:0022616)3.50879180
34chromatin assembly (GO:0031497)3.46793882
35negative regulation of histone methylation (GO:0031061)3.43847862
36DNA synthesis involved in DNA repair (GO:0000731)3.43768750
37negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.42682987
38establishment of integrated proviral latency (GO:0075713)3.41240233
39translesion synthesis (GO:0019985)3.40593950
40protein complex localization (GO:0031503)3.39384448
41formation of translation preinitiation complex (GO:0001731)3.38627241
42protein export from nucleus (GO:0006611)3.38509304
43positive regulation of chromosome segregation (GO:0051984)3.33592723
44dosage compensation (GO:0007549)3.32927912
45spliceosomal tri-snRNP complex assembly (GO:0000244)3.32864802
46regulation of sister chromatid cohesion (GO:0007063)3.31133289
47regulation of histone H3-K27 methylation (GO:0061085)3.23916083
48cellular protein complex localization (GO:0034629)3.23491618
49proline biosynthetic process (GO:0006561)3.23131228
50regulation of nucleobase-containing compound transport (GO:0032239)3.22059683
51gene silencing by RNA (GO:0031047)3.21316842
52telomere maintenance via semi-conservative replication (GO:0032201)3.21037705
53paraxial mesoderm development (GO:0048339)3.18776231
54DNA conformation change (GO:0071103)3.18669446
55regulation of RNA export from nucleus (GO:0046831)3.17656095
56regulation of spindle organization (GO:0090224)3.14129862
57nucleobase biosynthetic process (GO:0046112)3.14074708
58chromosome condensation (GO:0030261)3.12592302
59mitotic metaphase plate congression (GO:0007080)3.11751156
60double-strand break repair via nonhomologous end joining (GO:0006303)3.06528448
61non-recombinational repair (GO:0000726)3.06528448
62protein localization to chromosome (GO:0034502)3.06091526
63positive regulation of mitotic sister chromatid separation (GO:1901970)3.05613347
64positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.05613347
65positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.05613347
66RNA stabilization (GO:0043489)3.05407644
67mRNA stabilization (GO:0048255)3.05407644
68negative regulation of RNA splicing (GO:0033119)3.04723445
69DNA replication checkpoint (GO:0000076)3.04471185
70somatic hypermutation of immunoglobulin genes (GO:0016446)3.04007120
71somatic diversification of immune receptors via somatic mutation (GO:0002566)3.04007120
72chromatin assembly or disassembly (GO:0006333)3.03625360
73regulation of chromosome segregation (GO:0051983)3.02993459
74histone H2A monoubiquitination (GO:0035518)3.02795279
75regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.02539110
76* nuclear envelope organization (GO:0006998)3.02400274
77positive regulation of DNA-dependent DNA replication (GO:2000105)3.01200115
78negative regulation of mRNA processing (GO:0050686)3.00061726
79protein-DNA complex disassembly (GO:0032986)2.99947769
80nucleosome disassembly (GO:0006337)2.99947769
81ribosome assembly (GO:0042255)2.99682446
82IMP metabolic process (GO:0046040)2.99456950
83mitotic recombination (GO:0006312)2.98353023
84regulation of translational termination (GO:0006449)2.96911544
85postreplication repair (GO:0006301)2.96646690
86peptidyl-arginine omega-N-methylation (GO:0035247)2.96104314
87negative regulation of mRNA metabolic process (GO:1903312)2.94120863
88regulation of mammary gland epithelial cell proliferation (GO:0033599)2.93439132
89regulation of centrosome cycle (GO:0046605)2.91862940
90telomere maintenance via recombination (GO:0000722)2.91653717
91establishment of chromosome localization (GO:0051303)2.91098792
92gene silencing (GO:0016458)2.90563654
93DNA packaging (GO:0006323)2.89625114
94attachment of spindle microtubules to kinetochore (GO:0008608)2.88617636
95folic acid metabolic process (GO:0046655)2.88232387
96regulation of mitotic spindle organization (GO:0060236)2.87603911
97ribosome biogenesis (GO:0042254)2.87080756
98metaphase plate congression (GO:0051310)2.86830465
99purine nucleobase biosynthetic process (GO:0009113)2.85330959
100tRNA aminoacylation for protein translation (GO:0006418)2.84892174
101histone arginine methylation (GO:0034969)2.84314336
102kinetochore organization (GO:0051383)2.82075426
103establishment of apical/basal cell polarity (GO:0035089)2.81955352
104* mRNA transport (GO:0051028)2.81239069
105nucleobase-containing small molecule interconversion (GO:0015949)2.81152098
106negative regulation of chromosome segregation (GO:0051985)2.80842000
107regulation of centriole replication (GO:0046599)2.80652510
108meiotic chromosome segregation (GO:0045132)2.78087121
109negative regulation of DNA repair (GO:0045738)2.77943812
110regulation of translational elongation (GO:0006448)2.77588302
111peptidyl-arginine N-methylation (GO:0035246)2.76797496
112peptidyl-arginine methylation (GO:0018216)2.76797496
113histone H4-K12 acetylation (GO:0043983)2.76350567
114positive regulation of cell cycle checkpoint (GO:1901978)2.76147121
115amino acid activation (GO:0043038)2.74631245
116tRNA aminoacylation (GO:0043039)2.74631245
117regulation of helicase activity (GO:0051095)2.73767315
118rRNA transcription (GO:0009303)2.73739676
119regulation of gene silencing (GO:0060968)2.73453190
120nucleotide-excision repair, DNA gap filling (GO:0006297)2.72896759
121DNA replication-independent nucleosome organization (GO:0034724)2.72857502
122DNA replication-independent nucleosome assembly (GO:0006336)2.72857502
123ATP-dependent chromatin remodeling (GO:0043044)2.72574139
124maturation of SSU-rRNA (GO:0030490)2.72424432
125regulation of DNA damage checkpoint (GO:2000001)2.71981694
126synaptonemal complex assembly (GO:0007130)2.71742884
127regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.71502787
128spindle organization (GO:0007051)2.69549927
129telomere maintenance via telomere lengthening (GO:0010833)2.68155594
130positive regulation of SMAD protein import into nucleus (GO:0060391)2.67668498
131chromosome segregation (GO:0007059)2.67303775
132snRNA metabolic process (GO:0016073)2.66486386
133negative regulation of mitotic sister chromatid segregation (GO:0033048)2.66392429

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.44401351
2FOXM1_23109430_ChIP-Seq_U2OS_Human5.14839864
3E2F4_17652178_ChIP-ChIP_JURKAT_Human3.64037379
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.53917662
5MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse3.38683806
6FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.15816046
7* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.93653593
8EGR1_19374776_ChIP-ChIP_THP-1_Human2.88157921
9MYC_19079543_ChIP-ChIP_MESCs_Mouse2.81018687
10MYC_22102868_ChIP-Seq_BL_Human2.58566473
11* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.34332507
12* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.23032384
13* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.08696911
14E2F1_21310950_ChIP-Seq_MCF-7_Human2.07073812
15SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.05164573
16NELFA_20434984_ChIP-Seq_ESCs_Mouse2.03101684
17AR_21909140_ChIP-Seq_LNCAP_Human2.02555749
18XRN2_22483619_ChIP-Seq_HELA_Human1.98217436
19MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.86067869
20POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.81455349
21* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.78827333
22NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.73984777
23POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.71881194
24NANOG_18555785_ChIP-Seq_MESCs_Mouse1.68746586
25ZNF263_19887448_ChIP-Seq_K562_Human1.66504451
26CIITA_25753668_ChIP-Seq_RAJI_Human1.66175675
27KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.64167494
28KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.64167494
29KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.64167494
30EST1_17652178_ChIP-ChIP_JURKAT_Human1.54583717
31STAT3_1855785_ChIP-Seq_MESCs_Mouse1.54074375
32ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.52760368
33ETS1_20019798_ChIP-Seq_JURKAT_Human1.52128359
34TP63_19390658_ChIP-ChIP_HaCaT_Human1.51759274
35TP63_17297297_ChIP-ChIP_HaCaT_Human1.50452420
36CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.49303294
37SOX2_18555785_ChIP-Seq_MESCs_Mouse1.49198536
38CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.48416945
39VDR_21846776_ChIP-Seq_THP-1_Human1.48290370
40TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.46257543
41KDM5A_27292631_Chip-Seq_BREAST_Human1.45887198
42CREB1_15753290_ChIP-ChIP_HEK293T_Human1.44047671
43SALL1_21062744_ChIP-ChIP_HESCs_Human1.42970916
44CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.40477109
45ZFX_18555785_ChIP-Seq_MESCs_Mouse1.39722465
46HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.39667940
47* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.37881194
48TTF2_22483619_ChIP-Seq_HELA_Human1.36232196
49PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.35959164
50DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.33337318
51FOXP3_21729870_ChIP-Seq_TREG_Human1.31946561
52YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.31909278
53CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.30844212
54E2F1_18555785_ChIP-Seq_MESCs_Mouse1.29577445
55HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.29451002
56VDR_23849224_ChIP-Seq_CD4+_Human1.29400380
57* ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.28696736
58KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.28579148
59GABP_19822575_ChIP-Seq_HepG2_Human1.26983743
60NANOG_21062744_ChIP-ChIP_HESCs_Human1.24998026
61* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.23390387
62ERG_20887958_ChIP-Seq_HPC-7_Mouse1.22585748
63ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.21090865
64PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.20131463
65TCF3_18692474_ChIP-Seq_MEFs_Mouse1.19561079
66DCP1A_22483619_ChIP-Seq_HELA_Human1.18542170
67* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.18072986
68THAP11_20581084_ChIP-Seq_MESCs_Mouse1.16929498
69TFEB_21752829_ChIP-Seq_HELA_Human1.15917806
70TCF7_22412390_ChIP-Seq_EML_Mouse1.15855883
71NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.15711967
72NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.15467504
73* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.14846243
74* JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.14115235
75POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.13461613
76NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.10944388
77DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.07846031
78RACK7_27058665_Chip-Seq_MCF-7_Human1.06430408
79KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.06319196
80SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.06248655
81TCF3_18692474_ChIP-Seq_MESCs_Mouse1.05554761
82NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.05418910
83ESR1_15608294_ChIP-ChIP_MCF-7_Human1.05368005
84E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.05274468
85STAT6_21828071_ChIP-Seq_BEAS2B_Human1.04455714
86RBPJ_22232070_ChIP-Seq_NCS_Mouse1.04423254
87SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.04285069
88CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.04049147
89HOXB4_20404135_ChIP-ChIP_EML_Mouse1.03640543
90KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.03567479
91SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.02531278
92TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.00357860
93HIF1A_21447827_ChIP-Seq_MCF-7_Human1.00271510
94CLOCK_20551151_ChIP-Seq_293T_Human0.99715143
95KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.98634479
96ATF3_27146783_Chip-Seq_COLON_Human0.98418153
97* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.98100779
98P300_27058665_Chip-Seq_ZR-75-30cells_Human0.95674436
99GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.95321666
100LXR_22292898_ChIP-Seq_THP-1_Human0.95278220
101KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.94845438
102UTX_26944678_Chip-Seq_JUKART_Human0.94682855
103GABP_17652178_ChIP-ChIP_JURKAT_Human0.94268290
104STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.93173856
105ELF1_17652178_ChIP-ChIP_JURKAT_Human0.92752593
106KDM2B_26808549_Chip-Seq_DND41_Human0.91827095
107SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.91449055
108POU5F1_16518401_ChIP-PET_MESCs_Mouse0.90699525
109MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.89911476
110BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.89905790
111TBX5_21415370_ChIP-Seq_HL-1_Mouse0.89737153
112KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human0.89721803
113SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.89305435
114YY1_21170310_ChIP-Seq_MESCs_Mouse0.89238809
115CHD1_26751641_Chip-Seq_LNCaP_Human0.89079048
116ELK3_25401928_ChIP-Seq_HUVEC_Human0.88878893
117NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.88691932
118SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.87484633
119NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.86878314
120SOX2_18692474_ChIP-Seq_MESCs_Mouse0.86476959
121ELK1_19687146_ChIP-ChIP_HELA_Human0.86061075
122PKCTHETA_26484144_Chip-Seq_BREAST_Human0.85675499
123ZFP281_18757296_ChIP-ChIP_E14_Mouse0.85630372
124KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.85572543
125NCOR1_26117541_ChIP-Seq_K562_Human0.84660670
126MAF_26560356_Chip-Seq_TH1_Human0.84642693
127* SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.83233652

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability3.72133221
2MP0003111_abnormal_nucleus_morphology3.65897704
3MP0008057_abnormal_DNA_replication3.49493140
4MP0003693_abnormal_embryo_hatching3.36364478
5MP0004957_abnormal_blastocyst_morpholog3.35182385
6MP0003077_abnormal_cell_cycle3.22252885
7MP0010352_gastrointestinal_tract_polyps3.04062262
8MP0005076_abnormal_cell_differentiation2.47565546
9MP0001730_embryonic_growth_arrest2.41449270
10MP0005451_abnormal_body_composition2.34719248
11MP0008877_abnormal_DNA_methylation2.33660532
12MP0008007_abnormal_cellular_replicative2.29648385
13MP0008058_abnormal_DNA_repair2.26900192
14MP0010307_abnormal_tumor_latency2.23224444
15MP0000350_abnormal_cell_proliferation2.22301666
16MP0003705_abnormal_hypodermis_morpholog2.21767186
17MP0003123_paternal_imprinting2.06917856
18MP0004185_abnormal_adipocyte_glucose2.04923383
19MP0004197_abnormal_fetal_growth/weight/1.97159398
20MP0005380_embryogenesis_phenotype1.96311931
21MP0001672_abnormal_embryogenesis/_devel1.96311931
22MP0002084_abnormal_developmental_patter1.96307221
23MP0002653_abnormal_ependyma_morphology1.96198494
24MP0008932_abnormal_embryonic_tissue1.94934186
25MP0010030_abnormal_orbit_morphology1.88952306
26MP0002085_abnormal_embryonic_tissue1.86762933
27MP0001697_abnormal_embryo_size1.85516905
28MP0002396_abnormal_hematopoietic_system1.84043033
29MP0003984_embryonic_growth_retardation1.80749311
30MP0002088_abnormal_embryonic_growth/wei1.78048599
31MP0002086_abnormal_extraembryonic_tissu1.71252146
32MP0000537_abnormal_urethra_morphology1.69598359
33MP0002080_prenatal_lethality1.62045161
34MP0003890_abnormal_embryonic-extraembry1.60431558
35MP0009278_abnormal_bone_marrow1.58077157
36MP0001348_abnormal_lacrimal_gland1.57119691
37MP0004808_abnormal_hematopoietic_stem1.54763141
38MP0003121_genomic_imprinting1.48583565
39MP0001293_anophthalmia1.47217222
40MP0001661_extended_life_span1.46613034
41MP0009697_abnormal_copulation1.44164750
42MP0003786_premature_aging1.40848595
43MP0001849_ear_inflammation1.39824803
44MP0005410_abnormal_fertilization1.39406406
45MP0002210_abnormal_sex_determination1.38473396
46MP0003567_abnormal_fetal_cardiomyocyte1.36260976
47MP0002009_preneoplasia1.35496465
48MP0009053_abnormal_anal_canal1.35005727
49MP0005501_abnormal_skin_physiology1.34575586
50MP0001929_abnormal_gametogenesis1.33128306
51MP0003566_abnormal_cell_adhesion1.32058723
52MP0003119_abnormal_digestive_system1.29883598
53MP0000490_abnormal_crypts_of1.28589436
54MP0003453_abnormal_keratinocyte_physiol1.28436223
55MP0002796_impaired_skin_barrier1.26471475
56MP0000733_abnormal_muscle_development1.25553753
57MP0001145_abnormal_male_reproductive1.24083540
58MP0004233_abnormal_muscle_weight1.23959300
59MP0000313_abnormal_cell_death1.22954405
60MP0002019_abnormal_tumor_incidence1.15173589
61MP0005623_abnormal_meninges_morphology1.15148555
62MP0005023_abnormal_wound_healing1.14601501
63MP0001915_intracranial_hemorrhage1.14022916
64MP0004133_heterotaxia1.12614639
65MP0000428_abnormal_craniofacial_morphol1.09658327
66MP0003115_abnormal_respiratory_system1.09033938
67MP0001545_abnormal_hematopoietic_system1.07746632
68MP0005397_hematopoietic_system_phenotyp1.07746632
69MP0009703_decreased_birth_body1.03379808
70MP0002697_abnormal_eye_size1.03369374
71MP0002092_abnormal_eye_morphology1.02961511
72MP0009672_abnormal_birth_weight1.00883392
73MP0000703_abnormal_thymus_morphology1.00451282
74MP0002111_abnormal_tail_morphology1.00205560
75MP0003698_abnormal_male_reproductive0.99288757
76MP0000653_abnormal_sex_gland0.98483308
77MP0001216_abnormal_epidermal_layer0.96623479
78MP0002060_abnormal_skin_morphology0.96216680
79MP0000678_abnormal_parathyroid_gland0.96001431
80MP0002925_abnormal_cardiovascular_devel0.95766577
81MP0000003_abnormal_adipose_tissue0.95680076
82MP0005257_abnormal_intraocular_pressure0.93993604
83MP0003937_abnormal_limbs/digits/tail_de0.93802643
84MP0002877_abnormal_melanocyte_morpholog0.93005463
85MP0004264_abnormal_extraembryonic_tissu0.92647865
86MP0001873_stomach_inflammation0.92581087
87MP0003935_abnormal_craniofacial_develop0.91432840
88MP0003221_abnormal_cardiomyocyte_apopto0.91267584
89MP0006054_spinal_hemorrhage0.90651787
90MP0008260_abnormal_autophagy0.88682181
91MP0001346_abnormal_lacrimal_gland0.88401506
92MP0000432_abnormal_head_morphology0.87056666
93MP0003091_abnormal_cell_migration0.84910240
94MP0003283_abnormal_digestive_organ0.83499425
95MP0003950_abnormal_plasma_membrane0.82881016
96MP0005058_abnormal_lysosome_morphology0.81801117
97MP0005409_darkened_coat_color0.80452239
98MP0002282_abnormal_trachea_morphology0.80177133
99MP0008438_abnormal_cutaneous_collagen0.79989504
100MP0003861_abnormal_nervous_system0.78760903
101MP0005666_abnormal_adipose_tissue0.77775062
102MP0005621_abnormal_cell_physiology0.77226025
103MP0003942_abnormal_urinary_system0.77074768
104MP0006035_abnormal_mitochondrial_morpho0.76587225
105MP0003718_maternal_effect0.76012113
106MP0000579_abnormal_nail_morphology0.75597551
107MP0002089_abnormal_postnatal_growth/wei0.75097290
108MP0005384_cellular_phenotype0.74979545
109MP0003941_abnormal_skin_development0.73898893
110MP0002932_abnormal_joint_morphology0.72792043
111MP0010234_abnormal_vibrissa_follicle0.72590498
112MP0002006_tumorigenesis0.71688928
113MP0001286_abnormal_eye_development0.71270485
114MP0003656_abnormal_erythrocyte_physiolo0.71006741
115MP0000266_abnormal_heart_morphology0.70297005
116MP0002161_abnormal_fertility/fecundity0.69834958
117MP0001243_abnormal_dermal_layer0.69706967
118MP0009931_abnormal_skin_appearance0.69386775
119MP0003763_abnormal_thymus_physiology0.69377518
120MP0002398_abnormal_bone_marrow0.69238009
121MP0002970_abnormal_white_adipose0.68755075
122MP0003385_abnormal_body_wall0.68535767
123MP0003315_abnormal_perineum_morphology0.68019875
124MP0002166_altered_tumor_susceptibility0.67963340
125MP0000858_altered_metastatic_potential0.67530101
126MP0005375_adipose_tissue_phenotype0.67319164
127MP0008770_decreased_survivor_rate0.67210429
128MP0000627_abnormal_mammary_gland0.67132299
129MP0000358_abnormal_cell_content/0.66680411
130MP0002722_abnormal_immune_system0.66210952
131MP0003943_abnormal_hepatobiliary_system0.66129838
132MP0002249_abnormal_larynx_morphology0.65445996
133MP0003755_abnormal_palate_morphology0.64811764
134MP0000477_abnormal_intestine_morphology0.64810871
135MP0002114_abnormal_axial_skeleton0.64704831
136MP0010630_abnormal_cardiac_muscle0.64239159
137MP0000377_abnormal_hair_follicle0.63602195
138MP0009333_abnormal_splenocyte_physiolog0.62571178

Predicted human phenotypes

RankGene SetZ-score
1Ependymoma (HP:0002888)4.30837185
2Selective tooth agenesis (HP:0001592)3.67896790
3Abnormality of the astrocytes (HP:0100707)3.34803654
4Astrocytoma (HP:0009592)3.34803654
5Medulloblastoma (HP:0002885)3.32963137
6Short 4th metacarpal (HP:0010044)3.08280863
7Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.08280863
8Progressive muscle weakness (HP:0003323)2.88352359
9Increased nuchal translucency (HP:0010880)2.82758330
10Colon cancer (HP:0003003)2.81607657
11Insomnia (HP:0100785)2.81362312
12Microvesicular hepatic steatosis (HP:0001414)2.69679651
13Chromsome breakage (HP:0040012)2.68008721
14Neoplasm of the oral cavity (HP:0100649)2.65833064
15Glioma (HP:0009733)2.65776809
16Missing ribs (HP:0000921)2.65776148
17Deviation of the thumb (HP:0009603)2.65246011
18Proximal placement of thumb (HP:0009623)2.62276141
19Abnormality of the anterior horn cell (HP:0006802)2.58392788
20Degeneration of anterior horn cells (HP:0002398)2.58392788
21Rhabdomyosarcoma (HP:0002859)2.54194462
22Chromosomal breakage induced by crosslinking agents (HP:0003221)2.53772528
23Basal cell carcinoma (HP:0002671)2.49437186
24Abnormal gallbladder physiology (HP:0012438)2.48305996
25Cholecystitis (HP:0001082)2.48305996
26Impulsivity (HP:0100710)2.47072201
27Neoplasm of striated muscle (HP:0009728)2.47031874
28Hyperacusis (HP:0010780)2.46884619
29Squamous cell carcinoma (HP:0002860)2.45180025
30Ectopic kidney (HP:0000086)2.44199635
31Ankyloglossia (HP:0010296)2.43257985
32Abnormality of the labia minora (HP:0012880)2.39735678
33Agnosia (HP:0010524)2.37183340
34Renal duplication (HP:0000075)2.36882332
35Abnormality of oral frenula (HP:0000190)2.36426169
36Heterotopia (HP:0002282)2.31468331
37High pitched voice (HP:0001620)2.30133351
38Volvulus (HP:0002580)2.28358152
39Short humerus (HP:0005792)2.27238509
40Rib fusion (HP:0000902)2.27135786
41Progressive external ophthalmoplegia (HP:0000590)2.26341749
42Poikiloderma (HP:0001029)2.26234445
43Aplasia/hypoplasia of the humerus (HP:0006507)2.26173381
44Abnormal number of incisors (HP:0011064)2.25283688
45Reticulocytopenia (HP:0001896)2.23596168
46Abnormality of the 4th metacarpal (HP:0010012)2.23182650
4711 pairs of ribs (HP:0000878)2.22361279
48Abnormality of chromosome stability (HP:0003220)2.22148203
49Cortical dysplasia (HP:0002539)2.20920701
50Patellar aplasia (HP:0006443)2.20544312
51Long palpebral fissure (HP:0000637)2.18997735
52Meckel diverticulum (HP:0002245)2.17675505
53Aplasia/Hypoplasia of the uvula (HP:0010293)2.17069258
54Prominent nose (HP:0000448)2.16531262
55Deep philtrum (HP:0002002)2.14609918
56Entropion (HP:0000621)2.13786063
57Abnormality of the ileum (HP:0001549)2.12930424
58Ragged-red muscle fibers (HP:0003200)2.10489521
59Abnormality of abdominal situs (HP:0011620)2.08513007
60Abdominal situs inversus (HP:0003363)2.08513007
61Asymmetry of the thorax (HP:0001555)2.07630471
62Dysmetric saccades (HP:0000641)2.07555629
63Abnormality of the lower motor neuron (HP:0002366)2.07521228
64Broad face (HP:0000283)2.06661269
65Supernumerary spleens (HP:0009799)2.05836621
66Skull defect (HP:0001362)2.05507185
67Aplasia/Hypoplasia of the patella (HP:0006498)2.05347259
68Absent radius (HP:0003974)2.04722138
69Absent thumb (HP:0009777)2.04646868
70Broad distal phalanx of finger (HP:0009836)2.03920348
71Long eyelashes (HP:0000527)2.03882490
72Cafe-au-lait spot (HP:0000957)2.01091756
73Overriding aorta (HP:0002623)2.00857577
74Abnormality of glycolysis (HP:0004366)2.00409992
75Multiple enchondromatosis (HP:0005701)2.00241590
76Atresia of the external auditory canal (HP:0000413)1.99053227
77Biliary tract neoplasm (HP:0100574)1.98260759
78Malignant gastrointestinal tract tumors (HP:0006749)1.98087472
79Gastrointestinal carcinoma (HP:0002672)1.98087472
80Duodenal stenosis (HP:0100867)1.97551077
81Small intestinal stenosis (HP:0012848)1.97551077
82Trigonocephaly (HP:0000243)1.97128270
83Abnormality of the fingertips (HP:0001211)1.96859611
84Skin tags (HP:0010609)1.96661016
85Ankle contracture (HP:0006466)1.96226197
86Birth length less than 3rd percentile (HP:0003561)1.96152105
87Pseudobulbar signs (HP:0002200)1.95629801
88Septate vagina (HP:0001153)1.95474015
89Patellar dislocation (HP:0002999)1.94566593
90Premature rupture of membranes (HP:0001788)1.94391921
91Supernumerary ribs (HP:0005815)1.94329069
92Disproportionate tall stature (HP:0001519)1.93554908
93Achilles tendon contracture (HP:0001771)1.93324741
94Elfin facies (HP:0004428)1.93117275
95Facial hemangioma (HP:0000329)1.92480756
96Abnormality of the carotid arteries (HP:0005344)1.91923594
97Natal tooth (HP:0000695)1.91727959
98Myelodysplasia (HP:0002863)1.91532185
99Aplasia involving forearm bones (HP:0009822)1.91111945
100Absent forearm bone (HP:0003953)1.91111945
101Orthostatic hypotension (HP:0001278)1.90533005
102Broad thumb (HP:0011304)1.89154779
103Neoplasm of the pancreas (HP:0002894)1.88838668
104Abnormality of the umbilical cord (HP:0010881)1.88042244
105Renovascular hypertension (HP:0100817)1.87926273
106High anterior hairline (HP:0009890)1.87808533
107Pointed chin (HP:0000307)1.87396223
108Nephroblastoma (Wilms tumor) (HP:0002667)1.83955717
109Abnormality of the calcaneus (HP:0008364)1.83922253
110Spinal muscular atrophy (HP:0007269)1.83828067
111Broad palm (HP:0001169)1.83636301
112Bowel diverticulosis (HP:0005222)1.82479562
113Supernumerary bones of the axial skeleton (HP:0009144)1.82357734
114Shallow orbits (HP:0000586)1.81855469
115Abnormality of reticulocytes (HP:0004312)1.81700946
116Relative macrocephaly (HP:0004482)1.80070204
117Sloping forehead (HP:0000340)1.79960830
118Preauricular skin tag (HP:0000384)1.78881704
119Abnormality of the preputium (HP:0100587)1.77264331
120Advanced eruption of teeth (HP:0006288)1.76842039
121Amaurosis fugax (HP:0100576)1.76547803
122Aplasia/Hypoplasia of the sternum (HP:0006714)1.76001707
123Tracheoesophageal fistula (HP:0002575)1.75992618
124Breast hypoplasia (HP:0003187)1.74277699
125Obsessive-compulsive behavior (HP:0000722)1.73730164
126Abnormality of DNA repair (HP:0003254)1.73654067
127Sandal gap (HP:0001852)1.73587568
128Broad phalanges of the hand (HP:0009768)1.73569109
129Ulnar bowing (HP:0003031)1.72649863
130Reticulocytosis (HP:0001923)1.72478533
131Esophageal atresia (HP:0002032)1.72407890
132Cutaneous melanoma (HP:0012056)1.71842255
133Deep palmar crease (HP:0006191)1.71570835
134Protrusio acetabuli (HP:0003179)1.71553391
135Choanal atresia (HP:0000453)1.71173685
136Hand muscle atrophy (HP:0009130)1.71137941
137Overlapping toe (HP:0001845)1.69220123
138Urethral obstruction (HP:0000796)1.69196853
139Abnormality of the distal phalanx of the thumb (HP:0009617)1.69010325
140Sparse lateral eyebrow (HP:0005338)1.68925628
141Abnormality of cochlea (HP:0000375)1.68786674
142Metaphyseal cupping (HP:0003021)1.68523678
143Cerebral aneurysm (HP:0004944)1.68334484
144Distal lower limb amyotrophy (HP:0008944)1.68304486
145Trismus (HP:0000211)1.67737911
146Hypoplasia of the capital femoral epiphysis (HP:0003090)1.67396340
147Embryonal renal neoplasm (HP:0011794)1.67335021
148Premature ovarian failure (HP:0008209)1.67192658
149Dislocated radial head (HP:0003083)1.67128653
150Abnormal lung lobation (HP:0002101)1.66910588
151Ureteral duplication (HP:0000073)1.66101892
152Insidious onset (HP:0003587)1.65064219
153Termporal pattern (HP:0011008)1.65064219
154Spastic diplegia (HP:0001264)1.64763158
155Abnormal umbilical cord blood vessels (HP:0011403)1.62396104
156Single umbilical artery (HP:0001195)1.62396104
157Abnormality of the fetal cardiovascular system (HP:0010948)1.62396104
158Flat cornea (HP:0007720)1.61687341
159Abnormality of chromosome segregation (HP:0002916)1.61603932
160Duplication of thumb phalanx (HP:0009942)1.61359547
161Self-mutilation (HP:0000742)1.61118510

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK124.69563426
2CDC74.09413405
3SMG13.76108127
4EEF2K3.64341453
5NEK22.91482593
6MAP3K102.77492438
7IRAK32.63932877
8WEE12.63910311
9BRD42.41407466
10ICK2.37456488
11NME22.36432304
12TTK2.20553569
13BUB12.20291424
14PKN22.06392843
15PASK1.99984620
16PRPF4B1.91247578
17RPS6KB21.90622869
18NEK11.86762076
19CDK71.84855174
20PBK1.76080642
21TRIB31.75477381
22TSSK61.72315325
23ATR1.66239839
24CDK41.62709757
25EPHA21.58033335
26STK101.57024714
27MST1R1.55001314
28PLK11.54739608
29PAK41.50968428
30CHEK11.44059972
31PDK41.38237161
32PDK31.38237161
33TESK11.36559631
34MAP3K81.30503377
35CHEK21.29796044
36* MTOR1.29481087
37AURKB1.24650055
38TTN1.22675000
39SCYL21.19693312
40SRPK11.17382733
41CDK61.16394250
42ALK1.15900879
43LATS11.14213313
44RPS6KA41.14097722
45FGFR41.12050745
46TGFBR11.12018907
47TESK21.11627616
48STK41.07624979
49MKNK11.07430769
50STK31.03711889
51ATM1.02649351
52VRK20.98962574
53CDK20.97656000
54MAP3K140.97543059
55KSR20.96066337
56BRSK20.95656151
57FLT30.93114791
58TAOK20.92770613
59PIM10.91998050
60PDGFRA0.91538641
61BMX0.90977280
62PLK30.89688872
63TLK10.87289127
64DYRK30.87180664
65PRKD30.86483672
66LRRK20.86217567
67PAK20.85497676
68CAMK1D0.84584296
69TAF10.84580214
70LATS20.83626412
71CDK80.83205958
72MAP4K10.82872455
73PTK60.81558355
74MAPK110.79406543
75TYRO30.78342222
76ACVR1B0.74590790
77AURKA0.73874766
78FGFR10.73078852
79PNCK0.71460389
80BRAF0.71209011
81CDK10.69328240
82EIF2AK10.66217320
83CDK90.64795416
84MKNK20.64739214
85PLK40.63377641
86ERBB40.62547957
87RAF10.61746302
88MELK0.58545672
89MAP2K30.57445994
90PAK10.56593442
91PTK20.56335631
92RIPK10.56266787
93AKT20.54249566
94CCNB10.53910190
95CAMK1G0.51377761
96CSNK1D0.50957940
97MAP3K130.50428260
98ZAK0.50077661
99PDK20.49968523
100BRSK10.48228342
101EIF2AK20.47766607
102CDK11A0.46823172
103PRKDC0.46507364
104CDK150.45637782
105CSNK2A20.44694135
106CSNK1E0.44509919
107CHUK0.43851477
108SIK10.43154035
109IRAK20.42510425
110MAPKAPK30.42318390
111CDK180.42259552
112DDR20.41426309
113MAPK140.41233055
114RPS6KA10.41074199
115MAPK10.40278604
116PIM20.40242261
117MET0.38706993
118CDK140.37439077
119GRK60.36428317
120AKT10.36257522
121VRK10.35157509
122CSF1R0.34603421
123PRKCI0.34597013
124MAP3K90.34003117
125EIF2AK30.33961703
126CLK10.33915756
127NME10.33749987
128DYRK1B0.33457357
129MAPKAPK50.32851909
130GSK3B0.31951785
131ERN10.31003047
132RPS6KB10.29822892

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.29679193
2Mismatch repair_Homo sapiens_hsa034303.81047572
3* RNA transport_Homo sapiens_hsa030133.16477024
4Spliceosome_Homo sapiens_hsa030403.06411687
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.02546577
6Cell cycle_Homo sapiens_hsa041102.86552507
7One carbon pool by folate_Homo sapiens_hsa006702.86049576
8Base excision repair_Homo sapiens_hsa034102.73243845
9Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.52574007
10mRNA surveillance pathway_Homo sapiens_hsa030152.40357617
11Nucleotide excision repair_Homo sapiens_hsa034202.33534316
12Homologous recombination_Homo sapiens_hsa034402.31853832
13Fanconi anemia pathway_Homo sapiens_hsa034602.13420720
14Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.80312865
15RNA degradation_Homo sapiens_hsa030181.71744127
16Non-homologous end-joining_Homo sapiens_hsa034501.67813559
17p53 signaling pathway_Homo sapiens_hsa041151.58482288
18Ribosome_Homo sapiens_hsa030101.57484542
19Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.45588586
20Basal transcription factors_Homo sapiens_hsa030221.43940367
21Viral carcinogenesis_Homo sapiens_hsa052031.42256278
22RNA polymerase_Homo sapiens_hsa030201.40749484
23MicroRNAs in cancer_Homo sapiens_hsa052061.36830321
24Basal cell carcinoma_Homo sapiens_hsa052171.35932840
25Pyrimidine metabolism_Homo sapiens_hsa002401.32203763
26Notch signaling pathway_Homo sapiens_hsa043301.30504189
27HTLV-I infection_Homo sapiens_hsa051661.26945887
28Systemic lupus erythematosus_Homo sapiens_hsa053221.23822291
292-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.22565269
30Oocyte meiosis_Homo sapiens_hsa041141.20532645
31Small cell lung cancer_Homo sapiens_hsa052221.18116163
32Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.17546908
33Antigen processing and presentation_Homo sapiens_hsa046121.15895303
34Hippo signaling pathway_Homo sapiens_hsa043901.15210192
35Chronic myeloid leukemia_Homo sapiens_hsa052201.14614114
36Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.13874867
37Epstein-Barr virus infection_Homo sapiens_hsa051691.10959811
38Adherens junction_Homo sapiens_hsa045201.10681640
39Lysine degradation_Homo sapiens_hsa003101.08151706
40Central carbon metabolism in cancer_Homo sapiens_hsa052301.05430371
41Herpes simplex infection_Homo sapiens_hsa051681.03807548
42mTOR signaling pathway_Homo sapiens_hsa041500.98265554
43Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.97257508
44Biosynthesis of amino acids_Homo sapiens_hsa012300.96860280
45Colorectal cancer_Homo sapiens_hsa052100.95074564
46Transcriptional misregulation in cancer_Homo sapiens_hsa052020.94677014
47Thyroid cancer_Homo sapiens_hsa052160.93762141
48Hedgehog signaling pathway_Homo sapiens_hsa043400.93057445
49N-Glycan biosynthesis_Homo sapiens_hsa005100.92152953
50Selenocompound metabolism_Homo sapiens_hsa004500.91775450
51Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.89359446
52TGF-beta signaling pathway_Homo sapiens_hsa043500.87544103
53Bladder cancer_Homo sapiens_hsa052190.85891998
54Vitamin B6 metabolism_Homo sapiens_hsa007500.83665340
55Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.82296386
56Viral myocarditis_Homo sapiens_hsa054160.79811793
57Sulfur relay system_Homo sapiens_hsa041220.79476685
58Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.77335117
59Proteasome_Homo sapiens_hsa030500.76225437
60Proteoglycans in cancer_Homo sapiens_hsa052050.75450181
61Acute myeloid leukemia_Homo sapiens_hsa052210.74729158
62Glioma_Homo sapiens_hsa052140.74392266
63Pyruvate metabolism_Homo sapiens_hsa006200.73021277
64Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.72630195
65Thyroid hormone signaling pathway_Homo sapiens_hsa049190.72427833
66Other glycan degradation_Homo sapiens_hsa005110.71261985
67Pentose phosphate pathway_Homo sapiens_hsa000300.70711275
68Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.68750157
69HIF-1 signaling pathway_Homo sapiens_hsa040660.67445838
70Pathways in cancer_Homo sapiens_hsa052000.66447981
71Legionellosis_Homo sapiens_hsa051340.66099841
72Non-small cell lung cancer_Homo sapiens_hsa052230.63508210
73Endometrial cancer_Homo sapiens_hsa052130.62354780
74Prostate cancer_Homo sapiens_hsa052150.61840563
75Prion diseases_Homo sapiens_hsa050200.61834978
76Hepatitis B_Homo sapiens_hsa051610.61599949
77Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.61297302
78Wnt signaling pathway_Homo sapiens_hsa043100.60840451
79Apoptosis_Homo sapiens_hsa042100.60644900
80Purine metabolism_Homo sapiens_hsa002300.58459835
81Cyanoamino acid metabolism_Homo sapiens_hsa004600.56453011
82Steroid biosynthesis_Homo sapiens_hsa001000.56390160
83ErbB signaling pathway_Homo sapiens_hsa040120.56240882
84Galactose metabolism_Homo sapiens_hsa000520.54405547
85Insulin signaling pathway_Homo sapiens_hsa049100.54395203
86Focal adhesion_Homo sapiens_hsa045100.52694253
87Pancreatic cancer_Homo sapiens_hsa052120.52649585
88Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.52313058
89Shigellosis_Homo sapiens_hsa051310.52210097
90Tight junction_Homo sapiens_hsa045300.51686721
91Cysteine and methionine metabolism_Homo sapiens_hsa002700.50749239
92Alcoholism_Homo sapiens_hsa050340.50504086
93Dorso-ventral axis formation_Homo sapiens_hsa043200.47906044
94Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.46791545
95Neurotrophin signaling pathway_Homo sapiens_hsa047220.45073130
96Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.44320131
97Measles_Homo sapiens_hsa051620.44262781
98Carbon metabolism_Homo sapiens_hsa012000.44024978
99Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.41786770
100VEGF signaling pathway_Homo sapiens_hsa043700.41025130
101AMPK signaling pathway_Homo sapiens_hsa041520.40808486
102Inositol phosphate metabolism_Homo sapiens_hsa005620.40490590
103Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.39473211
104B cell receptor signaling pathway_Homo sapiens_hsa046620.39265025
105Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.39091979
106Leukocyte transendothelial migration_Homo sapiens_hsa046700.38698311
107Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.38104703
108Primary immunodeficiency_Homo sapiens_hsa053400.37901787
109Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.37879187
110Glucagon signaling pathway_Homo sapiens_hsa049220.37385881
111Influenza A_Homo sapiens_hsa051640.37330163
112PI3K-Akt signaling pathway_Homo sapiens_hsa041510.37175092
113AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.36858921
114T cell receptor signaling pathway_Homo sapiens_hsa046600.36459791
115Regulation of actin cytoskeleton_Homo sapiens_hsa048100.36435772
116ECM-receptor interaction_Homo sapiens_hsa045120.36104139
117Longevity regulating pathway - mammal_Homo sapiens_hsa042110.35603466
118Toxoplasmosis_Homo sapiens_hsa051450.34542677
119NF-kappa B signaling pathway_Homo sapiens_hsa040640.33325863
120Melanoma_Homo sapiens_hsa052180.33252386
121Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.33029940
122Fructose and mannose metabolism_Homo sapiens_hsa000510.32925719
123Renal cell carcinoma_Homo sapiens_hsa052110.31456333

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »