NUP210L

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1sperm-egg recognition (GO:0035036)9.70139980
2acrosome assembly (GO:0001675)9.69578834
3multicellular organism reproduction (GO:0032504)9.52758041
4male meiosis (GO:0007140)9.00872317
5binding of sperm to zona pellucida (GO:0007339)8.99208420
6acrosome reaction (GO:0007340)8.86237122
7epithelial cilium movement (GO:0003351)8.76929028
8cell-cell recognition (GO:0009988)8.76859462
9motile cilium assembly (GO:0044458)8.66900958
10plasma membrane fusion (GO:0045026)8.55080928
11epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)8.11311041
12* spermatid development (GO:0007286)8.04961207
13synaptonemal complex organization (GO:0070193)7.98221185
14cilium movement (GO:0003341)7.88737122
15reproduction (GO:0000003)7.76087619
16synaptonemal complex assembly (GO:0007130)7.63344503
17regulation of cilium movement (GO:0003352)7.32498714
18cell wall macromolecule metabolic process (GO:0044036)7.31039689
19cell wall macromolecule catabolic process (GO:0016998)7.31039689
20DNA methylation involved in gamete generation (GO:0043046)6.71014729
21single fertilization (GO:0007338)6.51216813
22male meiosis I (GO:0007141)6.32891170
23negative regulation of inclusion body assembly (GO:0090084)5.78127641
24fertilization (GO:0009566)5.70739996
25establishment of protein localization to Golgi (GO:0072600)5.69728967
26sperm capacitation (GO:0048240)5.67893205
27chromosome organization involved in meiosis (GO:0070192)5.61927432
28protein targeting to Golgi (GO:0000042)5.51582602
29meiotic nuclear division (GO:0007126)5.44926786
30spermatogenesis (GO:0007283)5.41095180
31male gamete generation (GO:0048232)5.39390894
32rRNA methylation (GO:0031167)5.35384234
33ventricular system development (GO:0021591)5.30537755
34retrograde transport, vesicle recycling within Golgi (GO:0000301)5.26048365
35meiosis I (GO:0007127)5.18057785
36microtubule depolymerization (GO:0007019)5.07633738
37gamete generation (GO:0007276)4.95559333
38meiotic cell cycle (GO:0051321)4.79759684
39monoubiquitinated protein deubiquitination (GO:0035520)4.76855072
40* germ cell development (GO:0007281)4.74957030
41* cellular process involved in reproduction in multicellular organism (GO:0022412)4.72867250
42rRNA modification (GO:0000154)4.66512043
43seminiferous tubule development (GO:0072520)4.65369652
44response to pheromone (GO:0019236)4.57999250
45gene silencing by RNA (GO:0031047)4.56325662
46single strand break repair (GO:0000012)4.54881652
47protein localization to Golgi apparatus (GO:0034067)4.51556399
48microtubule polymerization or depolymerization (GO:0031109)4.50822241
49nuclear pore complex assembly (GO:0051292)4.50282112
50meiotic chromosome segregation (GO:0045132)4.43322072
51regulation of inclusion body assembly (GO:0090083)4.29170711
52microtubule severing (GO:0051013)4.19458169
53DNA synthesis involved in DNA repair (GO:0000731)4.09399792
54organic cation transport (GO:0015695)4.08758558
55genitalia morphogenesis (GO:0035112)4.00149872
56regulation of microtubule-based movement (GO:0060632)3.97960246
57cell recognition (GO:0008037)3.95208378
58multicellular organismal reproductive process (GO:0048609)3.86459324
59reciprocal DNA recombination (GO:0035825)3.86448114
60reciprocal meiotic recombination (GO:0007131)3.86448114
61protein localization to cilium (GO:0061512)3.84579680
62nuclear pore organization (GO:0006999)3.77939364
63left/right pattern formation (GO:0060972)3.65633876
64meiotic cell cycle process (GO:1903046)3.64582193
65protein polyglutamylation (GO:0018095)3.63527256
66mitotic sister chromatid cohesion (GO:0007064)3.57188063
67regulation of centrosome duplication (GO:0010824)3.52716860
68regulation of centriole replication (GO:0046599)3.52081459
69phosphatidylethanolamine biosynthetic process (GO:0006646)3.50623917
70pore complex assembly (GO:0046931)3.47884737
71intraciliary transport (GO:0042073)3.47708287
72synapsis (GO:0007129)3.43744235
73calcium ion-dependent exocytosis (GO:0017156)3.42126148
74regulation of meiosis I (GO:0060631)3.41945664
75regulation of protein polyubiquitination (GO:1902914)3.39373834
76detection of light stimulus involved in sensory perception (GO:0050962)3.33062336
77detection of light stimulus involved in visual perception (GO:0050908)3.33062336
78DNA packaging (GO:0006323)3.29693842
79gene silencing (GO:0016458)3.29686449
80regulation of spindle checkpoint (GO:0090231)3.26369163
81phosphatidylethanolamine metabolic process (GO:0046337)3.25791183
82chromosome condensation (GO:0030261)3.23292563
83chaperone-mediated protein complex assembly (GO:0051131)3.21412179
84RNA destabilization (GO:0050779)3.20392819
85cellular ketone body metabolic process (GO:0046950)3.19256673
86microtubule nucleation (GO:0007020)3.18690010
87intra-Golgi vesicle-mediated transport (GO:0006891)3.18079208
88nucleus organization (GO:0006997)3.15704591
89multicellular organismal development (GO:0007275)3.12531321
90protein K48-linked deubiquitination (GO:0071108)3.11256868
91axoneme assembly (GO:0035082)3.11139847
92protein refolding (GO:0042026)3.10471257
93protein localization to chromosome, centromeric region (GO:0071459)3.06265466
94DNA alkylation (GO:0006305)3.02496998
95DNA methylation (GO:0006306)3.02496998
96tRNA methylation (GO:0030488)3.01890538
97spermatid nucleus differentiation (GO:0007289)2.99796552
98regulation of centrosome cycle (GO:0046605)2.99185209
99centriole replication (GO:0007099)2.99169112
100cilium organization (GO:0044782)2.98341293
101multicellular organismal movement (GO:0050879)2.97778226
102musculoskeletal movement (GO:0050881)2.97778226
103negative regulation of DNA repair (GO:0045738)2.97282444
104regulation of establishment of cell polarity (GO:2000114)2.96740357
105peptidyl-threonine dephosphorylation (GO:0035970)2.96038222
106microtubule-based movement (GO:0007018)2.95729018
107negative regulation of organelle assembly (GO:1902116)2.95580791
108sister chromatid cohesion (GO:0007062)2.94508728
109regulation of histone H3-K9 methylation (GO:0051570)2.91382057
110centriole assembly (GO:0098534)2.89323203
111female gamete generation (GO:0007292)2.89234360
112indole-containing compound catabolic process (GO:0042436)2.87495915
113indolalkylamine catabolic process (GO:0046218)2.87495915
114tryptophan catabolic process (GO:0006569)2.87495915
115photoreceptor cell maintenance (GO:0045494)2.87052499
116NAD biosynthetic process (GO:0009435)2.81141234
117cilium assembly (GO:0042384)2.80618010
118histone exchange (GO:0043486)2.80175654
119glycerol ether metabolic process (GO:0006662)2.78345167
120RNA methylation (GO:0001510)2.78337580
121regulation of Rab GTPase activity (GO:0032313)2.76352757
122positive regulation of Rab GTPase activity (GO:0032851)2.76352757
123DNA double-strand break processing (GO:0000729)2.76100327
124ketone body metabolic process (GO:1902224)2.75236284
125Golgi to endosome transport (GO:0006895)2.72471267
126translesion synthesis (GO:0019985)2.67321782
127cellular component assembly involved in morphogenesis (GO:0010927)2.65862980
128DNA replication-dependent nucleosome assembly (GO:0006335)2.65632646
129DNA replication-dependent nucleosome organization (GO:0034723)2.65632646
130protein K11-linked deubiquitination (GO:0035871)2.61664027
131histone H2A acetylation (GO:0043968)2.60414360
132blastocyst development (GO:0001824)2.55707104
133ether metabolic process (GO:0018904)2.54057641
134regulation of chromatin binding (GO:0035561)2.48558559
135cilium morphogenesis (GO:0060271)2.47561513
136histone H3-K9 methylation (GO:0051567)2.43404461
137cilium or flagellum-dependent cell motility (GO:0001539)14.5436231
138fusion of sperm to egg plasma membrane (GO:0007342)11.3940645
139sperm motility (GO:0030317)10.8050973
140piRNA metabolic process (GO:0034587)10.6785288
141axonemal dynein complex assembly (GO:0070286)10.4177697

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse5.51526325
2BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse5.32752726
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.87671316
4EZH2_22144423_ChIP-Seq_EOC_Human3.49186130
5ER_23166858_ChIP-Seq_MCF-7_Human3.05104015
6FUS_26573619_Chip-Seq_HEK293_Human3.02289965
7GBX2_23144817_ChIP-Seq_PC3_Human2.58102757
8CTBP2_25329375_ChIP-Seq_LNCAP_Human2.55473814
9TAF15_26573619_Chip-Seq_HEK293_Human2.53361123
10* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse2.44827248
11CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.37407971
12POU3F2_20337985_ChIP-ChIP_501MEL_Human2.28791074
13FLI1_27457419_Chip-Seq_LIVER_Mouse2.22889858
14CTBP1_25329375_ChIP-Seq_LNCAP_Human2.21762384
15EWS_26573619_Chip-Seq_HEK293_Human2.17585128
16FOXM1_23109430_ChIP-Seq_U2OS_Human2.00985757
17MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse12.2872667
18PCGF2_27294783_Chip-Seq_ESCs_Mouse1.98466051
19P300_19829295_ChIP-Seq_ESCs_Human1.94330470
20ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.90708949
21ELK4_26923725_Chip-Seq_MESODERM_Mouse1.88673052
22UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.79050685
23GATA1_26923725_Chip-Seq_HPCs_Mouse1.78094808
24SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.72866558
25IGF1R_20145208_ChIP-Seq_DFB_Human1.72430381
26AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.71953613
27PCGF2_27294783_Chip-Seq_NPCs_Mouse1.71275848
28ZFP57_27257070_Chip-Seq_ESCs_Mouse1.70246787
29EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.67373893
30AR_25329375_ChIP-Seq_VCAP_Human1.66816811
31STAT3_23295773_ChIP-Seq_U87_Human1.66780487
32* TP53_22573176_ChIP-Seq_HFKS_Human1.63484885
33ARNT_22903824_ChIP-Seq_MCF-7_Human1.62606693
34GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.62273827
35PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.61868811
36MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.58514683
37TP63_19390658_ChIP-ChIP_HaCaT_Human1.55397020
38SMAD4_21741376_ChIP-Seq_EPCs_Human1.54887405
39ZNF274_21170338_ChIP-Seq_K562_Hela1.52806966
40WDR5_24793694_ChIP-Seq_LNCAP_Human1.50396959
41* SMAD4_21799915_ChIP-Seq_A2780_Human1.49915776
42NFE2_27457419_Chip-Seq_LIVER_Mouse1.48340677
43TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.47686301
44E2F7_22180533_ChIP-Seq_HELA_Human1.47592567
45BCAT_22108803_ChIP-Seq_LS180_Human1.46702690
46ERA_21632823_ChIP-Seq_H3396_Human1.45599231
47SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.42819977
48STAT1_17558387_ChIP-Seq_HELA_Human1.42026982
49SMAD3_21741376_ChIP-Seq_EPCs_Human1.41869552
50VDR_22108803_ChIP-Seq_LS180_Human1.41549662
51* FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.39785266
52KAP1_22055183_ChIP-Seq_ESCs_Mouse1.39414770
53BMI1_23680149_ChIP-Seq_NPCS_Mouse1.39288070
54TDRD3_21172665_ChIP-Seq_MCF-7_Human1.37776095
55SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.37375818
56FOXA1_27270436_Chip-Seq_PROSTATE_Human1.37195875
57FOXA1_25329375_ChIP-Seq_VCAP_Human1.37195875
58AHR_22903824_ChIP-Seq_MCF-7_Human1.36712136
59NR3C1_21868756_ChIP-Seq_MCF10A_Human1.36036191
60GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.34706474
61RUNX2_22187159_ChIP-Seq_PCA_Human1.34217134
62SUZ12_27294783_Chip-Seq_NPCs_Mouse1.33825299
63PKCTHETA_26484144_Chip-Seq_BREAST_Human1.33621803
64FOXA1_21572438_ChIP-Seq_LNCaP_Human1.32799772
65ZNF217_24962896_ChIP-Seq_MCF-7_Human1.32037246
66HOXB7_26014856_ChIP-Seq_BT474_Human1.31496017
67PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.30343937
68KLF5_20875108_ChIP-Seq_MESCs_Mouse1.28508555
69CBP_20019798_ChIP-Seq_JUKART_Human1.27034009
70IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.27034009
71ESR1_20079471_ChIP-ChIP_T-47D_Human1.26623083
72CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.25791286
73KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.25472300
74STAT6_21828071_ChIP-Seq_BEAS2B_Human1.25117970
75TOP2B_26459242_ChIP-Seq_MCF-7_Human1.24672376
76FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.23401208
77EGR1_23403033_ChIP-Seq_LIVER_Mouse1.23386939
78RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.18723465
79RAC3_21632823_ChIP-Seq_H3396_Human1.16059725
80PADI4_21655091_ChIP-ChIP_MCF-7_Human1.15769250
81GATA3_21878914_ChIP-Seq_MCF-7_Human1.15523407
82ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.15461735
83OCT4_20526341_ChIP-Seq_ESCs_Human1.15174234
84EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.15048613
85* ETV1_20927104_ChIP-Seq_GIST48_Human1.14027832
86E2F4_17652178_ChIP-ChIP_JURKAT_Human1.13563065
87NANOG_20526341_ChIP-Seq_ESCs_Human1.13195274
88NCOR_22424771_ChIP-Seq_293T_Human1.12295713
89* TAL1_26923725_Chip-Seq_HPCs_Mouse1.11545188
90MYC_19829295_ChIP-Seq_ESCs_Human1.11231242
91TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.09787215
92CRX_20693478_ChIP-Seq_RETINA_Mouse1.07418854
93* PHF8_20622853_ChIP-Seq_HELA_Human1.07389931
94* RBPJ_21746931_ChIP-Seq_IB4_Human1.06262151
95GATA3_21867929_ChIP-Seq_CD8_Mouse1.05782168
96CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.04367116
97LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.04341294
98SOX2_22085726_ChIP-Seq_NPCs_Mouse1.04159522
99* TBL1_22424771_ChIP-Seq_293T_Human1.03898570
100ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.03835184
101OCT4_21477851_ChIP-Seq_ESCs_Mouse1.03471035
102* CBX2_22325352_ChIP-Seq_293T-Rex_Human1.03265187
103GF1_26923725_Chip-Seq_HPCs_Mouse1.03243974
104KDM2B_26808549_Chip-Seq_REH_Human1.03148621
105PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.02980946
106IRF8_21731497_ChIP-ChIP_J774_Mouse1.02826276
107GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.02555104
108NANOG_19829295_ChIP-Seq_ESCs_Human1.01832512
109SOX2_19829295_ChIP-Seq_ESCs_Human1.01832512
110FLI1_21867929_ChIP-Seq_TH2_Mouse1.01757896
111EZH2_27294783_Chip-Seq_NPCs_Mouse1.01468203
112* PIAS1_25552417_ChIP-Seq_VCAP_Human1.00929535
113VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.00796814
114* CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.00393414
115AUTS2_25519132_ChIP-Seq_293T-REX_Human1.00390726
116* CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.00232529
117TCF4_22108803_ChIP-Seq_LS180_Human1.00109027
118AR_21572438_ChIP-Seq_LNCaP_Human0.99679764
119SETDB1_19884257_ChIP-Seq_MESCs_Mouse0.99371237
120CDX2_22108803_ChIP-Seq_LS180_Human0.98282101
121* PCGF4_22325352_ChIP-Seq_293T-Rex_Human0.98137893
122FOXM1_26456572_ChIP-Seq_MCF-7_Human0.97613200
123* HNFA_21074721_ChIP-Seq_CACO-2_Human0.97497443
124NOTCH1_21737748_ChIP-Seq_TLL_Human0.97226583
125* MYB_26560356_Chip-Seq_TH1_Human0.96598448
126MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.96459418
127PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.96226124
128IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.95133179
129* OCT4_18555785_Chip-Seq_ESCs_Mouse0.94144917
130CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.93870422
131* CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.93771454
132PRDM14_20953172_ChIP-Seq_ESCs_Human0.93213387
133NANOG_18555785_Chip-Seq_ESCs_Mouse0.93045353
134RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.92748124
135HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.92594396
136TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.90701163
137POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.90701163
138RUNX1_26923725_Chip-Seq_HPCs_Mouse0.89658201
139FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.89580060
140STAT3_18555785_Chip-Seq_ESCs_Mouse0.89400005
141GATA3_21867929_ChIP-Seq_TH1_Mouse0.88446822
142P300_18555785_Chip-Seq_ESCs_Mouse0.85887406
143SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.84897807
144KLF4_18555785_Chip-Seq_ESCs_Mouse0.84811874
145GATA3_26560356_Chip-Seq_TH1_Human0.84186556
146P53_22387025_ChIP-Seq_ESCs_Mouse0.84011261
147MYB_21317192_ChIP-Seq_ERMYB_Mouse0.84006936
148ESRRB_18555785_Chip-Seq_ESCs_Mouse0.83925981
149PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.83862491
150* MYB_26560356_Chip-Seq_TH2_Human0.83694312
151* PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.83584031
152EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.83150206
153ETS1_22383799_ChIP-Seq_G1ME_Mouse0.82771666
154RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.82741200
155RNF2_27304074_Chip-Seq_NSC_Mouse0.81907971
156MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.81468515
157* NFYB_21822215_ChIP-Seq_K562_Human0.81426117
158TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.81346946
159P53_21459846_ChIP-Seq_SAOS-2_Human0.81184345
160MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.79744362
161ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.79091612
162TCF4_23295773_ChIP-Seq_U87_Human0.78962085
163EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.78824706
164STAT3_18555785_ChIP-Seq_MESCs_Mouse0.78165159
165IRF8_22096565_ChIP-ChIP_GC-B_Human0.77968382
166LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.77741974
167* CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.76764531
168EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.76695067
169SUZ12_18555785_Chip-Seq_ESCs_Mouse0.76582671
170SOX9_26525672_Chip-Seq_HEART_Mouse0.76488616
171PU1_27457419_Chip-Seq_LIVER_Mouse0.76148726
172RXRA_24833708_ChIP-Seq_LIVER_Mouse0.75593626
173SALL1_21062744_ChIP-ChIP_HESCs_Human0.75435460
174* SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.74892108

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008877_abnormal_DNA_methylation5.75928239
2MP0003698_abnormal_male_reproductive5.12586051
3MP0001929_abnormal_gametogenesis4.93760128
4MP0002210_abnormal_sex_determination3.61815431
5MP0008057_abnormal_DNA_replication3.24315486
6MP0001968_abnormal_touch/_nociception3.12561783
7MP0001145_abnormal_male_reproductive3.05330874
8MP0002736_abnormal_nociception_after2.79453330
9MP0002161_abnormal_fertility/fecundity2.78161296
10MP0002653_abnormal_ependyma_morphology2.76029544
11MP0000653_abnormal_sex_gland2.61913292
12MP0005623_abnormal_meninges_morphology2.40561922
13MP0003718_maternal_effect2.23280983
14MP0010094_abnormal_chromosome_stability2.10221232
15MP0005410_abnormal_fertilization12.8071465
16MP0005551_abnormal_eye_electrophysiolog1.95932313
17MP0008058_abnormal_DNA_repair1.92785288
18MP0002160_abnormal_reproductive_system1.89852311
19MP0005423_abnormal_somatic_nervous1.86800697
20MP0000427_abnormal_hair_cycle1.82289133
21MP0004808_abnormal_hematopoietic_stem1.81546934
22MP0001986_abnormal_taste_sensitivity1.80508217
23MP0008007_abnormal_cellular_replicative1.78399791
24MP0002735_abnormal_chemical_nociception1.72050493
25MP0001188_hyperpigmentation1.67526201
26MP0005253_abnormal_eye_physiology1.61206376
27MP0009278_abnormal_bone_marrow1.61011367
28MP0005310_abnormal_salivary_gland1.60443879
29MP0005397_hematopoietic_system_phenotyp1.59028649
30MP0001545_abnormal_hematopoietic_system1.59028649
31MP0001486_abnormal_startle_reflex1.56133112
32MP0002282_abnormal_trachea_morphology1.52787783
33MP0008995_early_reproductive_senescence1.52108646
34MP0003111_abnormal_nucleus_morphology1.49327854
35MP0005670_abnormal_white_adipose1.47956649
36MP0003786_premature_aging1.47568545
37MP0010307_abnormal_tumor_latency1.35055773
38MP0003077_abnormal_cell_cycle1.30564271
39MP0005083_abnormal_biliary_tract1.30488077
40MP0000383_abnormal_hair_follicle1.29852042
41MP0001485_abnormal_pinna_reflex1.21297024
42MP0005647_abnormal_sex_gland1.15249666
43MP0004043_abnormal_pH_regulation1.14511173
44MP0003693_abnormal_embryo_hatching1.10230063
45MP0009745_abnormal_behavioral_response1.09689399
46MP0001501_abnormal_sleep_pattern1.09414192
47MP0005389_reproductive_system_phenotype1.06785208
48MP0005395_other_phenotype1.05437020
49MP0008872_abnormal_physiological_respon1.04243920
50MP0003880_abnormal_central_pattern0.98295638
51MP0000470_abnormal_stomach_morphology0.97616366
52MP0002734_abnormal_mechanical_nocicepti0.95924223
53MP0004264_abnormal_extraembryonic_tissu0.95532708
54MP0000538_abnormal_urinary_bladder0.94691129
55MP0002822_catalepsy0.93880445
56MP0001835_abnormal_antigen_presentation0.93348662
57MP0002067_abnormal_sensory_capabilities0.92452267
58MP0003943_abnormal_hepatobiliary_system0.87700340
59MP0002928_abnormal_bile_duct0.86322837
60MP0000569_abnormal_digit_pigmentation0.84652612
61MP0002837_dystrophic_cardiac_calcinosis0.84533102
62MP0002405_respiratory_system_inflammati0.84434917
63MP0003787_abnormal_imprinting0.82625453
64MP0004134_abnormal_chest_morphology0.81717191
65MP0001293_anophthalmia0.81205879
66MP0008875_abnormal_xenobiotic_pharmacok0.81064407
67MP0001970_abnormal_pain_threshold0.78712174
68MP0005503_abnormal_tendon_morphology0.77136152
69MP0004742_abnormal_vestibular_system0.76849863
70MP0005367_renal/urinary_system_phenotyp0.76819265
71MP0000516_abnormal_urinary_system0.76819265
72MP0003763_abnormal_thymus_physiology0.76685245
73MP0002272_abnormal_nervous_system0.76626870
74MP0010386_abnormal_urinary_bladder0.76483199
75MP0005386_behavior/neurological_phenoty0.75854056
76MP0004924_abnormal_behavior0.75854056
77MP0005646_abnormal_pituitary_gland0.75535398
78MP0010678_abnormal_skin_adnexa0.74273018
79MP0003878_abnormal_ear_physiology0.74222580
80MP0005377_hearing/vestibular/ear_phenot0.74222580
81MP0002572_abnormal_emotion/affect_behav0.74061107
82MP0003936_abnormal_reproductive_system0.73968913
83MP0002254_reproductive_system_inflammat0.73278395
84MP0003950_abnormal_plasma_membrane0.73041501
85MP0005332_abnormal_amino_acid0.72666279
86MP0002184_abnormal_innervation0.71776514
87MP0001119_abnormal_female_reproductive0.71575525
88MP0002229_neurodegeneration0.71035959
89MP0003879_abnormal_hair_cell0.69951633
90MP0004215_abnormal_myocardial_fiber0.68807003
91MP0002398_abnormal_bone_marrow0.68791864
92MP0001348_abnormal_lacrimal_gland0.67371854
93MP0002557_abnormal_social/conspecific_i0.67199006
94MP0003195_calcinosis0.66882939
95MP0000313_abnormal_cell_death0.66126664
96MP0008961_abnormal_basal_metabolism0.65950690
97MP0003137_abnormal_impulse_conducting0.65373088
98MP0001664_abnormal_digestion0.64715398
99MP0001730_embryonic_growth_arrest0.63672755
100MP0004133_heterotaxia0.63058707
101MP0005645_abnormal_hypothalamus_physiol0.62993936
102MP0001756_abnormal_urination0.62877472
103MP0001963_abnormal_hearing_physiology0.61701838
104MP0002396_abnormal_hematopoietic_system0.61345677
105MP0000350_abnormal_cell_proliferation0.60540848
106MP0003115_abnormal_respiratory_system0.60141143
107MP0001502_abnormal_circadian_rhythm0.59876146
108MP0002693_abnormal_pancreas_physiology0.59396454
109MP0004957_abnormal_blastocyst_morpholog0.58298185
110MP0004085_abnormal_heartbeat0.58095062
111MP0005167_abnormal_blood-brain_barrier0.58015692
112MP0002092_abnormal_eye_morphology0.57768199
113MP0003646_muscle_fatigue0.57735314
114MP0002102_abnormal_ear_morphology0.57001533
115MP0003119_abnormal_digestive_system0.56592797
116MP0001800_abnormal_humoral_immune0.55619702
117MP0003699_abnormal_female_reproductive0.55561243
118MP0000703_abnormal_thymus_morphology0.55466668
119MP0005076_abnormal_cell_differentiation0.55299168
120MP0000685_abnormal_immune_system0.55048449
121MP0002452_abnormal_antigen_presenting0.54372017
122MP0001765_abnormal_ion_homeostasis0.53559536
123MP0002723_abnormal_immune_serum0.53250216
124MP0005380_embryogenesis_phenotype0.53066043
125MP0001672_abnormal_embryogenesis/_devel0.53066043
126MP0002234_abnormal_pharynx_morphology0.52738828
127MP0000015_abnormal_ear_pigmentation0.52607262
128MP0000716_abnormal_immune_system0.52215016
129MP0001851_eye_inflammation0.51935763
130MP0000689_abnormal_spleen_morphology0.49992986
131MP0003011_delayed_dark_adaptation0.49319633
132MP0003984_embryonic_growth_retardation0.49144772
133MP0001853_heart_inflammation0.49020311
134MP0002420_abnormal_adaptive_immunity0.48354563
135MP0004197_abnormal_fetal_growth/weight/0.48253053
136MP0001697_abnormal_embryo_size0.47864867
137MP0001819_abnormal_immune_cell0.47736864
138MP0000358_abnormal_cell_content/0.46814742
139MP0002429_abnormal_blood_cell0.45301489
140MP0001873_stomach_inflammation0.45245394
141MP0002088_abnormal_embryonic_growth/wei0.45132429
142MP0002019_abnormal_tumor_incidence0.44127156
143MP0002722_abnormal_immune_system0.43485243
144MP0005671_abnormal_response_to0.43439929
145MP0005174_abnormal_tail_pigmentation0.42525086
146MP0002084_abnormal_developmental_patter0.42050687
147MP0002080_prenatal_lethality0.41778311
148MP0001790_abnormal_immune_system0.41413819
149MP0005387_immune_system_phenotype0.41413819
150MP0003448_altered_tumor_morphology0.41388199
151MP0005391_vision/eye_phenotype0.39742350
152MP0010352_gastrointestinal_tract_polyps0.39609464
153MP0001727_abnormal_embryo_implantation0.39502504
154MP0001915_intracranial_hemorrhage0.39152132
155MP0009785_altered_susceptibility_to0.38754111
156MP0009046_muscle_twitch0.37054965
157MP0009115_abnormal_fat_cell0.36790692
158MP0001984_abnormal_olfaction0.36264184
159MP0003436_decreased_susceptibility_to0.35718504
160MP0005409_darkened_coat_color0.35631260
161MP0001919_abnormal_reproductive_system0.35425751
162MP0002085_abnormal_embryonic_tissue0.34809739

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)8.69615793
2Abnormal respiratory epithelium morphology (HP:0012253)8.25909036
3Abnormal respiratory motile cilium morphology (HP:0005938)8.25909036
4Rhinitis (HP:0012384)7.67865787
5Abnormal ciliary motility (HP:0012262)6.96666544
6Nasal polyposis (HP:0100582)6.28108709
7Chronic bronchitis (HP:0004469)6.27582463
8Infertility (HP:0000789)5.67525596
9Abnormality of the nasal mucosa (HP:0000433)5.17801847
10Attenuation of retinal blood vessels (HP:0007843)4.61811175
11Bronchiectasis (HP:0002110)4.60067894
12Bronchitis (HP:0012387)4.50344103
13Chronic hepatic failure (HP:0100626)4.36690252
14Nephronophthisis (HP:0000090)4.31715492
15Bony spicule pigmentary retinopathy (HP:0007737)3.95348935
16Recurrent otitis media (HP:0000403)3.43722492
17Recurrent sinusitis (HP:0011108)3.43576285
18Abnormality of the renal medulla (HP:0100957)3.39228899
19Male infertility (HP:0003251)3.35510354
20Hyperkalemia (HP:0002153)3.34516479
21Recurrent bronchitis (HP:0002837)3.32185197
22Abnormality of the lower motor neuron (HP:0002366)3.30084120
23Chromosomal breakage induced by crosslinking agents (HP:0003221)3.28113722
24Pancreatic cysts (HP:0001737)3.25985995
25Chromsome breakage (HP:0040012)3.21260261
26Congenital stationary night blindness (HP:0007642)3.08370149
27Type II lissencephaly (HP:0007260)3.04604712
28Cerebellar dysplasia (HP:0007033)3.01501095
29Abnormal spermatogenesis (HP:0008669)3.00299689
30Tubulointerstitial nephritis (HP:0001970)2.94708180
31Gonadotropin excess (HP:0000837)2.93952567
32Fibular hypoplasia (HP:0003038)2.79576756
33Absent frontal sinuses (HP:0002688)2.71676594
34Cone-rod dystrophy (HP:0000548)2.69619126
35Molar tooth sign on MRI (HP:0002419)2.68151749
36Abnormality of midbrain morphology (HP:0002418)2.68151749
37Progressive inability to walk (HP:0002505)2.67829967
38Absent thumb (HP:0009777)2.61789919
39Inability to walk (HP:0002540)2.61165431
40Horizontal nystagmus (HP:0000666)2.60771708
41Severe visual impairment (HP:0001141)2.60436599
42Aplasia/Hypoplasia of the uvula (HP:0010293)2.59708749
43Tubular atrophy (HP:0000092)2.51686907
44Abnormality of macular pigmentation (HP:0008002)2.51107198
45Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.47367157
46Abnormality of alanine metabolism (HP:0010916)2.47367157
47Hyperalaninemia (HP:0003348)2.47367157
48Truncal obesity (HP:0001956)2.46282696
49Hypoplasia of the capital femoral epiphysis (HP:0003090)2.43992534
50Progressive cerebellar ataxia (HP:0002073)2.42157315
51Congenital sensorineural hearing impairment (HP:0008527)2.41648248
52Amyotrophic lateral sclerosis (HP:0007354)2.41531427
53Facial hemangioma (HP:0000329)2.41018369
54Gaze-evoked nystagmus (HP:0000640)2.37554042
55Oligodactyly (hands) (HP:0001180)2.37487499
56Pendular nystagmus (HP:0012043)2.34017439
57Abnormality of DNA repair (HP:0003254)2.33227601
58Decreased circulating renin level (HP:0003351)2.33059105
59Chronic sinusitis (HP:0011109)2.32881629
60Abnormality of the ileum (HP:0001549)2.31956908
61Impulsivity (HP:0100710)2.31727709
62Hyperventilation (HP:0002883)2.31690156
63Meckel diverticulum (HP:0002245)2.31629860
64Azoospermia (HP:0000027)2.30209963
65Duodenal stenosis (HP:0100867)2.27278980
66Small intestinal stenosis (HP:0012848)2.27278980
67Postaxial foot polydactyly (HP:0001830)2.27198949
68Impaired proprioception (HP:0010831)2.21999418
69True hermaphroditism (HP:0010459)2.21699302
70Tubulointerstitial abnormality (HP:0001969)2.21314637
71Abnormality of the preputium (HP:0100587)2.20450994
72Degeneration of anterior horn cells (HP:0002398)2.18967849
73Abnormality of the anterior horn cell (HP:0006802)2.18967849
74Abnormality of chromosome stability (HP:0003220)2.17485952
7511 pairs of ribs (HP:0000878)2.15980756
76Short ribs (HP:0000773)2.15654618
77Aplasia/Hypoplasia of the earlobes (HP:0009906)2.15601583
78Poikiloderma (HP:0001029)2.14964834
79Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)2.14379963
80Small hand (HP:0200055)2.14353323
81Upper motor neuron abnormality (HP:0002127)2.12909550
82Amelogenesis imperfecta (HP:0000705)2.11899097
83Decreased central vision (HP:0007663)2.11114552
84Aplasia/Hypoplasia of the tibia (HP:0005772)2.10467458
85Supernumerary spleens (HP:0009799)2.10302528
86Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.07076029
87Absent epiphyses (HP:0010577)2.07076029
88Clubbing of toes (HP:0100760)2.05595100
89Absent radius (HP:0003974)2.01423034
90Protruding tongue (HP:0010808)2.01031530
91Respiratory insufficiency due to defective ciliary clearance (HP:0200073)12.4927404
92Dynein arm defect of respiratory motile cilia (HP:0012255)11.4318838
93Absent/shortened dynein arms (HP:0200106)11.4318838
94Abnormality of dental color (HP:0011073)1.99699200
95Stage 5 chronic kidney disease (HP:0003774)1.98565325
96Abnormal rod and cone electroretinograms (HP:0008323)1.96316127
97Choroideremia (HP:0001139)1.96168426
98Abnormality of the duodenum (HP:0002246)1.94886521
99Renal dysplasia (HP:0000110)1.94865123
100Congenital hepatic fibrosis (HP:0002612)1.94513942
101Patellar aplasia (HP:0006443)1.93583849
102Absent forearm bone (HP:0003953)1.92911497
103Aplasia involving forearm bones (HP:0009822)1.92911497
104Medial flaring of the eyebrow (HP:0010747)1.92357670
105Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.91440373
106Abnormal albumin level (HP:0012116)1.90511402
107Hypoalbuminemia (HP:0003073)1.90511402
108Abnormality of the renal cortex (HP:0011035)1.90339261
109Volvulus (HP:0002580)1.90279346
110Facial cleft (HP:0002006)1.89734975
111Spontaneous abortion (HP:0005268)1.88786684
112Clumsiness (HP:0002312)1.84523663
113Polyuria (HP:0000103)1.83672377
114Aplasia/Hypoplasia of the patella (HP:0006498)1.82522600
115Absent speech (HP:0001344)1.81817892
116Abnormality of the dental root (HP:0006486)1.80740620
117Taurodontia (HP:0000679)1.80740620
118Abnormality of permanent molar morphology (HP:0011071)1.80740620
119Resting tremor (HP:0002322)1.76302941
120Febrile seizures (HP:0002373)1.75328392
121Oculomotor apraxia (HP:0000657)1.75122313
122Median cleft lip (HP:0000161)1.74070608
123Breast carcinoma (HP:0003002)1.72243334
124Type I transferrin isoform profile (HP:0003642)1.72020691
125J-shaped sella turcica (HP:0002680)1.71941067
126Short thumb (HP:0009778)1.71580631
127Abnormality of the frontal sinuses (HP:0002687)1.71342804
128Sandal gap (HP:0001852)1.71103455
129Male pseudohermaphroditism (HP:0000037)1.71061690
130Abnormality of molar morphology (HP:0011070)1.69692793
131Abnormality of molar (HP:0011077)1.69692793
132Aplasia/Hypoplasia of the fibula (HP:0006492)1.68204087
133Heterotopia (HP:0002282)1.68108608
134Abnormality of potassium homeostasis (HP:0011042)1.66116829
135Short thorax (HP:0010306)1.63058371
136Abnormality of dentin (HP:0010299)1.62281299
137Ectopic kidney (HP:0000086)1.61284603
138Facial diplegia (HP:0001349)1.61120654
139Abnormality of the dental pulp (HP:0006479)1.57368334
140Selective tooth agenesis (HP:0001592)1.55057438
141Microglossia (HP:0000171)1.52605495
142Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.52466216
143Tubulointerstitial fibrosis (HP:0005576)1.51769065
144Deformed sella turcica (HP:0002681)1.50806562
145Short femoral neck (HP:0100864)1.48639949
146Postaxial hand polydactyly (HP:0001162)1.48384661
147Dyschromatopsia (HP:0007641)1.48204890
148Bell-shaped thorax (HP:0001591)1.44653464
149Broad distal phalanx of finger (HP:0009836)1.43270447
150Polydipsia (HP:0001959)1.42535959
151Abnormal drinking behavior (HP:0030082)1.42535959
152Flattened epiphyses (HP:0003071)1.39693414
153Abnormality of the epiphyses of the phalanges of the hand (HP:0005920)1.39079356
154Abnormality involving the epiphyses of the upper limbs (HP:0003839)1.39051250
155Nephroblastoma (Wilms tumor) (HP:0002667)1.38288814
156Sloping forehead (HP:0000340)1.37948979
157Pancreatic fibrosis (HP:0100732)1.36686232
158Cystic liver disease (HP:0006706)1.35883107
159Aplasia/Hypoplasia of the tongue (HP:0010295)1.32860593
160Short nail (HP:0001799)1.32695128
161Acute myeloid leukemia (HP:0004808)1.31327734
162Abnormality of the epiphyses of the hand (HP:0005924)1.28384570
163Nephropathy (HP:0000112)1.27957442
164Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)1.25968035
165Conjunctival telangiectasia (HP:0000524)1.25320579
166Abnormal biliary tract physiology (HP:0012439)1.25184309
167Bile duct proliferation (HP:0001408)1.25184309
168Embryonal renal neoplasm (HP:0011794)1.24645007
169Large eyes (HP:0001090)1.23975540
170Retrobulbar optic neuritis (HP:0100654)1.22714009

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK38.41472424
2PDK48.41472424
3FRK5.68829130
4PDK25.54373091
5TESK14.24730173
6PRKD33.16375224
7ICK2.76134754
8TLK12.50848916
9PNCK2.48835712
10NEK22.46974289
11PTK2B2.40546736
12PLK22.35661918
13TRIM282.19752336
14MAP4K21.93243350
15WNK41.80763018
16TAOK31.75720355
17STK391.74040765
18AKT31.73940439
19NTRK31.63722299
20CDC71.54163159
21STK31.53938523
22WEE11.48323668
23NUAK11.40681703
24WNK31.35919354
25ADRBK21.34617749
26MAPKAPK31.31110357
27CASK1.25574113
28CDK121.24215134
29MAPK131.21632157
30OXSR11.21594023
31MAP3K41.13841602
32PIK3CG1.12663063
33MAPK151.12548621
34PINK11.09586656
35PASK1.08295289
36TTK1.06559075
37CCNB11.05571494
38WNK11.03878425
39ATR1.03659600
40CAMK1G0.96595574
41DYRK1B0.95075961
42ERBB30.92750522
43PDPK10.92281179
44MAP2K20.90856205
45CLK10.90008337
46EEF2K0.89610330
47VRK10.86926135
48SIK20.85392909
49IKBKB0.85312713
50TIE10.83071280
51CHEK10.82794397
52MAP4K10.81582064
53BRSK20.76187615
54STK380.75484410
55PDK10.73686815
56MET0.73607563
57PIK3CA0.70132078
58DYRK30.65674909
59BMPR1B0.62617574
60STK160.60340023
61STK100.60133848
62ATM0.58863692
63CHEK20.58406978
64ADRBK10.53990883
65SGK20.53939489
66PAK20.53322355
67GRK60.52371700
68PLK10.51808391
69BRD40.50951784
70MAP2K10.50164026
71PLK40.48385330
72GRK50.48205812
73MTOR0.47447120
74INSRR0.46649324
75CDK190.45620495
76SRPK10.45516217
77STK40.45392079
78STK38L0.44005920
79EIF2AK30.43925813
80BTK0.43829227
81RPS6KB20.42655182
82PRKCI0.42396974
83MARK10.42326989
84RPS6KA40.41132227
85IRAK10.40378806
86PIM10.40337207
87ZAP700.39688764
88MAP3K140.38427187
89CDK40.38121078
90PBK0.38097186
91ZAK0.37937311
92TEC0.37703086
93EPHB10.37570680
94CSNK1D0.36835634
95PRKG10.35943778
96IRAK20.34168525
97TESK20.34044124
98CAMK10.33999741
99PRKCE0.33115915
100MAP3K20.32549790
101EIF2AK10.32319476
102TYRO30.31873997
103MARK30.31748153
104SGK10.31437290
105MAP3K100.31104477
106MAPK110.30892789
107RPS6KA60.29927030
108BRAF0.29773967
109TRPM70.29713764
110CDK30.28252545
111PRKCG0.28207307
112PRKAA10.27595645
113MKNK20.27291051
114SGK4940.27173075
115SGK2230.27173075
116PAK10.27151009
117CSF1R0.26775962
118NEK60.25970723
119CDK70.25470069
120MAPK10.25345162
121CAMK2A0.24922184
122MKNK10.24674988
123PDGFRB0.24281813
124RPS6KB10.24048515
125CAMK1D0.24012779
126AURKB0.23902470
127CDK20.22622477
128PRKCQ0.21725464
129CDK10.21666529
130CHUK0.20641114
131TYK20.20314247
132MUSK0.19741507
133YES10.18898030
134CSK0.18484744
135ACVR1B0.17918673
136MAPKAPK50.16991657
137GRK10.16669221
138TSSK60.16346488
139TXK0.15727603
140PAK40.15600804
141JAK30.15366953
142MAPK70.14925508
143CDK60.14863269
144HCK0.14109150
145TBK10.13341087
146EIF2AK20.12884855
147KIT0.11641829
148MAP2K30.11631077
149PRKDC0.11128813
150GSK3B0.10909868
151PIM20.10841289
152RPS6KA50.10808362
153PLK30.10629935
154MAPK80.10277446
155SYK0.10181441

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007503.81648996
2Fanconi anemia pathway_Homo sapiens_hsa034603.50425991
3Basal transcription factors_Homo sapiens_hsa030223.11891691
4Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.92919236
5Glycolysis / Gluconeogenesis_Homo sapiens_hsa000102.86774896
6Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.56726549
7Dorso-ventral axis formation_Homo sapiens_hsa043202.44030844
8Taste transduction_Homo sapiens_hsa047422.39181322
9Sulfur relay system_Homo sapiens_hsa041222.31670092
10Fatty acid biosynthesis_Homo sapiens_hsa000612.30499193
11Olfactory transduction_Homo sapiens_hsa047402.29329993
12Pyruvate metabolism_Homo sapiens_hsa006202.28051104
13Antigen processing and presentation_Homo sapiens_hsa046122.27778787
14Nitrogen metabolism_Homo sapiens_hsa009102.05556120
15* RNA transport_Homo sapiens_hsa030132.02617642
16Phototransduction_Homo sapiens_hsa047442.00219693
17Butanoate metabolism_Homo sapiens_hsa006501.99466407
18Selenocompound metabolism_Homo sapiens_hsa004501.98043570
19RNA polymerase_Homo sapiens_hsa030201.94811213
20Pentose phosphate pathway_Homo sapiens_hsa000301.92464844
21Glucagon signaling pathway_Homo sapiens_hsa049221.90452764
22mRNA surveillance pathway_Homo sapiens_hsa030151.89562311
23Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.80981072
24alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.76547725
25Nicotine addiction_Homo sapiens_hsa050331.74752089
26Maturity onset diabetes of the young_Homo sapiens_hsa049501.73861648
27Circadian rhythm_Homo sapiens_hsa047101.69798790
28Linoleic acid metabolism_Homo sapiens_hsa005911.65429473
29Homologous recombination_Homo sapiens_hsa034401.60316141
30Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.59337126
31Oocyte meiosis_Homo sapiens_hsa041141.58767650
32Cell cycle_Homo sapiens_hsa041101.55868056
33Legionellosis_Homo sapiens_hsa051341.53609000
34Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.53241864
35Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.51950809
36Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.51269732
37Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.43303633
38Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.36071184
39Measles_Homo sapiens_hsa051621.34434848
40Herpes simplex infection_Homo sapiens_hsa051681.32143929
41Tryptophan metabolism_Homo sapiens_hsa003801.31057443
42B cell receptor signaling pathway_Homo sapiens_hsa046621.29101596
43RNA degradation_Homo sapiens_hsa030181.28769214
44Alcoholism_Homo sapiens_hsa050341.28029736
45Propanoate metabolism_Homo sapiens_hsa006401.27518228
46DNA replication_Homo sapiens_hsa030301.24751663
47Circadian entrainment_Homo sapiens_hsa047131.24191773
48Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.24003615
49Base excision repair_Homo sapiens_hsa034101.20641751
50Lysine degradation_Homo sapiens_hsa003101.20632745
51Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.20052157
52Influenza A_Homo sapiens_hsa051641.17474924
53Spliceosome_Homo sapiens_hsa030401.15583748
54Toxoplasmosis_Homo sapiens_hsa051451.12236818
55Systemic lupus erythematosus_Homo sapiens_hsa053221.12162353
56Purine metabolism_Homo sapiens_hsa002301.11567580
57Glycerolipid metabolism_Homo sapiens_hsa005611.08195725
58Carbohydrate digestion and absorption_Homo sapiens_hsa049731.06370067
59Calcium signaling pathway_Homo sapiens_hsa040201.05199659
60NF-kappa B signaling pathway_Homo sapiens_hsa040641.04938804
61Viral carcinogenesis_Homo sapiens_hsa052031.03183846
62Pyrimidine metabolism_Homo sapiens_hsa002401.02577288
63Serotonergic synapse_Homo sapiens_hsa047261.02543996
64Glutamatergic synapse_Homo sapiens_hsa047241.00609194
65Epstein-Barr virus infection_Homo sapiens_hsa051690.99872028
66Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.97106034
67Steroid hormone biosynthesis_Homo sapiens_hsa001400.96123752
68Morphine addiction_Homo sapiens_hsa050320.94976997
69Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.94595851
70Primary bile acid biosynthesis_Homo sapiens_hsa001200.94289754
71Mismatch repair_Homo sapiens_hsa034300.94071924
72Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.93641800
73Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.93164622
74Primary immunodeficiency_Homo sapiens_hsa053400.92371653
75Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.91889684
76Intestinal immune network for IgA production_Homo sapiens_hsa046720.91798043
77HTLV-I infection_Homo sapiens_hsa051660.90526558
78One carbon pool by folate_Homo sapiens_hsa006700.90073501
79Fructose and mannose metabolism_Homo sapiens_hsa000510.89276877
80Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.89188344
81Non-homologous end-joining_Homo sapiens_hsa034500.89118705
82Sphingolipid metabolism_Homo sapiens_hsa006000.88782932
83Fatty acid metabolism_Homo sapiens_hsa012120.86581923
84Fatty acid degradation_Homo sapiens_hsa000710.86243153
85Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.83111191
86p53 signaling pathway_Homo sapiens_hsa041150.82942442
87Allograft rejection_Homo sapiens_hsa053300.82820585
88Glycosaminoglycan degradation_Homo sapiens_hsa005310.81213019
89T cell receptor signaling pathway_Homo sapiens_hsa046600.80399653
90Nucleotide excision repair_Homo sapiens_hsa034200.76367866
91Small cell lung cancer_Homo sapiens_hsa052220.75431169
92Transcriptional misregulation in cancer_Homo sapiens_hsa052020.74971330
93Huntingtons disease_Homo sapiens_hsa050160.73559745
94Glycerophospholipid metabolism_Homo sapiens_hsa005640.72062877
95Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.71971596
96NOD-like receptor signaling pathway_Homo sapiens_hsa046210.69565943
97ABC transporters_Homo sapiens_hsa020100.69513038
98Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.69256889
99beta-Alanine metabolism_Homo sapiens_hsa004100.67864442
100Malaria_Homo sapiens_hsa051440.67201488
101TGF-beta signaling pathway_Homo sapiens_hsa043500.66546507
102Jak-STAT signaling pathway_Homo sapiens_hsa046300.66027770
103Retinol metabolism_Homo sapiens_hsa008300.65994605
104Regulation of autophagy_Homo sapiens_hsa041400.65676896
105Viral myocarditis_Homo sapiens_hsa054160.63954809
106Salmonella infection_Homo sapiens_hsa051320.62365806
107Osteoclast differentiation_Homo sapiens_hsa043800.62075591
108Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.61775224
109Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.61017054
110Cysteine and methionine metabolism_Homo sapiens_hsa002700.60111254
111Chemical carcinogenesis_Homo sapiens_hsa052040.60067406
112Graft-versus-host disease_Homo sapiens_hsa053320.59106533
113Renin secretion_Homo sapiens_hsa049240.59097630
114cAMP signaling pathway_Homo sapiens_hsa040240.58537281
115Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.58367758
116Long-term depression_Homo sapiens_hsa047300.56354165
117Insulin secretion_Homo sapiens_hsa049110.56134436
118Salivary secretion_Homo sapiens_hsa049700.55966796
119TNF signaling pathway_Homo sapiens_hsa046680.54848052
120Ether lipid metabolism_Homo sapiens_hsa005650.54794579
121HIF-1 signaling pathway_Homo sapiens_hsa040660.54274047
122Estrogen signaling pathway_Homo sapiens_hsa049150.54150635
123Peroxisome_Homo sapiens_hsa041460.53809921
124Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.53413000
125Central carbon metabolism in cancer_Homo sapiens_hsa052300.53142322
126GABAergic synapse_Homo sapiens_hsa047270.50708218
127Shigellosis_Homo sapiens_hsa051310.49868956
128Hematopoietic cell lineage_Homo sapiens_hsa046400.49830777
129Cholinergic synapse_Homo sapiens_hsa047250.48323445
130Dopaminergic synapse_Homo sapiens_hsa047280.47721937
131Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.46611278
132Phosphatidylinositol signaling system_Homo sapiens_hsa040700.46159261
133Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.45830435
134mTOR signaling pathway_Homo sapiens_hsa041500.45695056
135Arachidonic acid metabolism_Homo sapiens_hsa005900.45196929
136VEGF signaling pathway_Homo sapiens_hsa043700.45142431
137Leishmaniasis_Homo sapiens_hsa051400.44233667
138Ovarian steroidogenesis_Homo sapiens_hsa049130.43678584
139PPAR signaling pathway_Homo sapiens_hsa033200.43617750
140Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.42871500
141Inositol phosphate metabolism_Homo sapiens_hsa005620.42345672
142Toll-like receptor signaling pathway_Homo sapiens_hsa046200.41129309
143Type II diabetes mellitus_Homo sapiens_hsa049300.41046342
144Amphetamine addiction_Homo sapiens_hsa050310.40668228
145Metabolic pathways_Homo sapiens_hsa011000.40152396
146cGMP-PKG signaling pathway_Homo sapiens_hsa040220.38908002
147Mineral absorption_Homo sapiens_hsa049780.38906618
148Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.38899000
149Gastric acid secretion_Homo sapiens_hsa049710.36299865
150Hedgehog signaling pathway_Homo sapiens_hsa043400.35866687
151Rheumatoid arthritis_Homo sapiens_hsa053230.35775932
152Hepatitis B_Homo sapiens_hsa051610.35238644
153Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.35202638
154Thyroid hormone signaling pathway_Homo sapiens_hsa049190.34739112
155Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.31217857
156Carbon metabolism_Homo sapiens_hsa012000.27871734
157RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.27731105

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