NUTF2P2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of isotype switching to IgG isotypes (GO:0048302)7.57887252
2positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)6.88754101
3regulation of immunoglobulin secretion (GO:0051023)6.63138651
4regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)5.93551018
5regulation of vitamin D biosynthetic process (GO:0060556)5.59040927
6auditory receptor cell differentiation (GO:0042491)5.39362138
7respiratory chain complex IV assembly (GO:0008535)5.14671651
8positive regulation of DNA recombination (GO:0045911)5.08202295
9negative regulation of B cell apoptotic process (GO:0002903)5.01107602
10positive regulation of isotype switching (GO:0045830)4.93753882
11regulation of regulatory T cell differentiation (GO:0045589)4.80854360
12protein complex biogenesis (GO:0070271)4.61479057
13regulation of vitamin metabolic process (GO:0030656)4.57686706
14positive regulation of cell fate commitment (GO:0010455)4.49254846
15regulation of podosome assembly (GO:0071801)4.44502847
16regulation of chemokine biosynthetic process (GO:0045073)4.37034204
17regulation of mitochondrial fission (GO:0090140)4.26005845
18mitochondrial respiratory chain complex assembly (GO:0033108)4.19339454
19L-fucose catabolic process (GO:0042355)4.00486913
20fucose catabolic process (GO:0019317)4.00486913
21L-fucose metabolic process (GO:0042354)4.00486913
22response to pheromone (GO:0019236)3.96053620
23mitochondrial respiratory chain complex I assembly (GO:0032981)3.93418164
24NADH dehydrogenase complex assembly (GO:0010257)3.93418164
25mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.93418164
26cytochrome complex assembly (GO:0017004)3.92172219
27mechanosensory behavior (GO:0007638)3.91785951
28water-soluble vitamin biosynthetic process (GO:0042364)3.76166172
29regulation of mitochondrial translation (GO:0070129)3.75744246
30pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130)3.73343736
31positive regulation of chemokine biosynthetic process (GO:0045080)3.67270337
32pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174)3.57209039
33UMP metabolic process (GO:0046049)3.57209039
34pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173)3.57209039
35UMP biosynthetic process (GO:0006222)3.57209039
36positive regulation of immunoglobulin production (GO:0002639)3.55295768
37regulation of MHC class II biosynthetic process (GO:0045346)3.53059510
38establishment of protein localization to mitochondrial membrane (GO:0090151)3.52844720
39microtubule depolymerization (GO:0007019)3.52556378
40DNA catabolic process, exonucleolytic (GO:0000738)3.52142391
41DNA double-strand break processing (GO:0000729)3.48769441
42mannosylation (GO:0097502)3.48059283
43regulation of chronic inflammatory response (GO:0002676)3.43783649
44regulation of isotype switching (GO:0045191)3.37600342
45pyrimidine nucleoside monophosphate metabolic process (GO:0009129)3.36226410
46negative regulation of monooxygenase activity (GO:0032769)3.32121783
47spermatid nucleus differentiation (GO:0007289)3.26967301
48positive regulation of interleukin-17 production (GO:0032740)3.26774397
49maturation of SSU-rRNA (GO:0030490)3.24731523
50rRNA modification (GO:0000154)3.24385828
51sperm motility (GO:0030317)3.19621726
52inner ear receptor cell differentiation (GO:0060113)3.18798063
53cellular extravasation (GO:0045123)3.15932698
54positive regulation of activated T cell proliferation (GO:0042104)3.12829298
55protein-cofactor linkage (GO:0018065)3.09998589
56microtubule polymerization or depolymerization (GO:0031109)3.06197580
57protein polyglutamylation (GO:0018095)3.03326437
58negative regulation of DNA recombination (GO:0045910)3.02053377
59centriole replication (GO:0007099)3.00096498
60mismatch repair (GO:0006298)2.96304805
61GTP biosynthetic process (GO:0006183)2.96098923
62regulation of immunoglobulin production (GO:0002637)2.92713795
63behavioral response to nicotine (GO:0035095)2.90273334
64mast cell activation (GO:0045576)2.88614476
65positive regulation of granulocyte differentiation (GO:0030854)2.88463206
66pyrimidine ribonucleoside biosynthetic process (GO:0046132)2.85267661
67hair cell differentiation (GO:0035315)2.83402258
68negative regulation of cell fate specification (GO:0009996)2.81256213
69DNA replication-dependent nucleosome organization (GO:0034723)2.79604002
70DNA replication-dependent nucleosome assembly (GO:0006335)2.79604002
71modulation of growth of symbiont involved in interaction with host (GO:0044144)2.77730836
72regulation of growth of symbiont in host (GO:0044126)2.77730836
73negative regulation of growth of symbiont in host (GO:0044130)2.77730836
74negative regulation of growth of symbiont involved in interaction with host (GO:0044146)2.77730836
75cobalamin metabolic process (GO:0009235)2.77627362
76negative regulation of phagocytosis (GO:0050765)2.76319358
77mast cell degranulation (GO:0043303)2.76285983
78mast cell activation involved in immune response (GO:0002279)2.76285983
79pyrimidine ribonucleotide biosynthetic process (GO:0009220)2.74511223
80recombinational repair (GO:0000725)2.73935279
81positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.73910640
82double-strand break repair via homologous recombination (GO:0000724)2.73175062
83fusion of sperm to egg plasma membrane (GO:0007342)2.72606479
84GPI anchor biosynthetic process (GO:0006506)2.71634791
85positive regulation of B cell mediated immunity (GO:0002714)2.71314888
86positive regulation of immunoglobulin mediated immune response (GO:0002891)2.71314888
87fucose metabolic process (GO:0006004)2.67352369
88RNA phosphodiester bond hydrolysis, endonucleolytic (GO:0090502)2.66864737
89GPI anchor metabolic process (GO:0006505)2.66623489
90cellular biogenic amine catabolic process (GO:0042402)2.66111022
91amine catabolic process (GO:0009310)2.66111022
92preassembly of GPI anchor in ER membrane (GO:0016254)2.66065319
93postreplication repair (GO:0006301)2.66037475
94RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.65588339
95tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.65588339
96DNA damage response, detection of DNA damage (GO:0042769)2.60225461
97negative regulation of heart contraction (GO:0045822)2.59285833
98cellular ketone body metabolic process (GO:0046950)2.58987362
99DNA ligation (GO:0006266)2.58596405
100CD4-positive, alpha-beta T cell differentiation (GO:0043367)2.57936563

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse5.57458300
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.40267474
3SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.66317371
4HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.57191027
5EST1_17652178_ChIP-ChIP_JURKAT_Human3.08794673
6NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.93162724
7JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.92886395
8GABP_17652178_ChIP-ChIP_JURKAT_Human2.76203361
9ETS1_20019798_ChIP-Seq_JURKAT_Human2.61769447
10HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.46965470
11E2F7_22180533_ChIP-Seq_HELA_Human2.46623021
12IGF1R_20145208_ChIP-Seq_DFB_Human2.31572441
13VDR_23849224_ChIP-Seq_CD4+_Human2.30099081
14NOTCH1_21737748_ChIP-Seq_TLL_Human2.15192545
15E2F4_17652178_ChIP-ChIP_JURKAT_Human2.13138389
16ZNF274_21170338_ChIP-Seq_K562_Hela2.13001192
17MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.08730338
18MYC_18555785_ChIP-Seq_MESCs_Mouse2.00764357
19FOXP3_21729870_ChIP-Seq_TREG_Human1.95532132
20ELF1_17652178_ChIP-ChIP_JURKAT_Human1.93476099
21MYC_18940864_ChIP-ChIP_HL60_Human1.92132500
22ELK1_19687146_ChIP-ChIP_HELA_Human1.88074629
23EWS_26573619_Chip-Seq_HEK293_Human1.85045876
24THAP11_20581084_ChIP-Seq_MESCs_Mouse1.79451243
25TP53_22573176_ChIP-Seq_HFKS_Human1.78695159
26CREB1_15753290_ChIP-ChIP_HEK293T_Human1.75426141
27CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.73503165
28PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.70844304
29FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.59643789
30MYC_18358816_ChIP-ChIP_MESCs_Mouse1.58205583
31YY1_21170310_ChIP-Seq_MESCs_Mouse1.57475955
32DCP1A_22483619_ChIP-Seq_HELA_Human1.57241198
33LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.56267571
34CTBP1_25329375_ChIP-Seq_LNCAP_Human1.53158155
35TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.52980103
36YY1_22570637_ChIP-Seq_MALME-3M_Human1.46706367
37ERA_21632823_ChIP-Seq_H3396_Human1.43905954
38PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.42505730
39TAF15_26573619_Chip-Seq_HEK293_Human1.41701333
40BP1_19119308_ChIP-ChIP_Hs578T_Human1.37812272
41SRF_21415370_ChIP-Seq_HL-1_Mouse1.36827163
42GABP_19822575_ChIP-Seq_HepG2_Human1.36478435
43FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.36337214
44MYC_19030024_ChIP-ChIP_MESCs_Mouse1.34926428
45CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.34646254
46EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.34126896
47NANOG_20526341_ChIP-Seq_ESCs_Human1.33664937
48GBX2_23144817_ChIP-Seq_PC3_Human1.32594718
49MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.30792890
50POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.29925679
51NANOG_19829295_ChIP-Seq_ESCs_Human1.29499531
52SOX2_19829295_ChIP-Seq_ESCs_Human1.29499531
53FLI1_27457419_Chip-Seq_LIVER_Mouse1.28597002
54FOXA1_27270436_Chip-Seq_PROSTATE_Human1.26641284
55FOXA1_25329375_ChIP-Seq_VCAP_Human1.26641284
56GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.25584335
57NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.24340566
58FUS_26573619_Chip-Seq_HEK293_Human1.21315231
59TTF2_22483619_ChIP-Seq_HELA_Human1.21272063
60EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.21092911
61MYC_19829295_ChIP-Seq_ESCs_Human1.20628189
62PHF8_20622853_ChIP-Seq_HELA_Human1.20342361
63GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.17464500
64CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.17458951
65UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.15959200
66PCGF2_27294783_Chip-Seq_NPCs_Mouse1.15561799
67RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.15414211
68HNFA_21074721_ChIP-Seq_CACO-2_Human1.15024633
69GATA6_21074721_ChIP-Seq_CACO-2_Human1.14792467
70CBX2_22325352_ChIP-Seq_293T-Rex_Human1.11207653
71NCOR_22424771_ChIP-Seq_293T_Human1.11100297
72EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.07855097
73NFE2_27457419_Chip-Seq_LIVER_Mouse1.07442302
74PCGF2_27294783_Chip-Seq_ESCs_Mouse1.07373206
75XRN2_22483619_ChIP-Seq_HELA_Human1.03709609
76ER_23166858_ChIP-Seq_MCF-7_Human1.02381378
77RBPJ_21746931_ChIP-Seq_IB4_Human1.02340397
78ETV1_20927104_ChIP-Seq_GIST48_Human1.02207051
79PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.01987369
80CTBP2_25329375_ChIP-Seq_LNCAP_Human1.01771970
81CBP_20019798_ChIP-Seq_JUKART_Human1.00400881
82IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.00400881
83POU3F2_20337985_ChIP-ChIP_501MEL_Human1.00223392
84P53_21459846_ChIP-Seq_SAOS-2_Human0.97163418
85CTCF_20526341_ChIP-Seq_ESCs_Human0.95466809
86GATA3_26560356_Chip-Seq_TH2_Human0.94528929
87ETV2_25802403_ChIP-Seq_MESCs_Mouse0.92929929
88NFYB_21822215_ChIP-Seq_K562_Human0.92848392
89AUTS2_25519132_ChIP-Seq_293T-REX_Human0.91864266
90E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.91439199
91GATA3_21878914_ChIP-Seq_MCF-7_Human0.90856917
92FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.90795740
93KLF5_20875108_ChIP-Seq_MESCs_Mouse0.90618898
94RAC3_21632823_ChIP-Seq_H3396_Human0.90208769
95P300_19829295_ChIP-Seq_ESCs_Human0.89824753
96SUZ12_27294783_Chip-Seq_NPCs_Mouse0.88976430
97SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.87946084
98TAF2_19829295_ChIP-Seq_ESCs_Human0.87005775
99VDR_22108803_ChIP-Seq_LS180_Human0.86787482
100PADI4_21655091_ChIP-ChIP_MCF-7_Human0.84881137

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004147_increased_porphyrin_level4.41455456
2MP0001873_stomach_inflammation3.74250977
3MP0004782_abnormal_surfactant_physiolog3.71691881
4MP0000465_gastrointestinal_hemorrhage3.43497506
5MP0001835_abnormal_antigen_presentation3.06690385
6MP0005410_abnormal_fertilization3.02190725
7MP0001986_abnormal_taste_sensitivity2.75931563
8MP0008872_abnormal_physiological_respon2.60994345
9MP0003646_muscle_fatigue2.48549929
10MP0001853_heart_inflammation2.45311231
11MP0008058_abnormal_DNA_repair2.35348011
12MP0009780_abnormal_chondrocyte_physiolo2.35298128
13MP0004742_abnormal_vestibular_system2.34878391
14MP0003718_maternal_effect2.34096623
15MP0000372_irregular_coat_pigmentation2.31848634
16MP0005670_abnormal_white_adipose2.12622112
17MP0008877_abnormal_DNA_methylation2.10430991
18MP0008875_abnormal_xenobiotic_pharmacok2.08394429
19MP0002653_abnormal_ependyma_morphology2.06987317
20MP0002277_abnormal_respiratory_mucosa2.05249210
21MP0004142_abnormal_muscle_tone1.88535638
22MP0001905_abnormal_dopamine_level1.85987246
23MP0004043_abnormal_pH_regulation1.85491388
24MP0005171_absent_coat_pigmentation1.76981516
25MP0003283_abnormal_digestive_organ1.74825632
26MP0003786_premature_aging1.73952964
27MP0010094_abnormal_chromosome_stability1.70076747
28MP0001502_abnormal_circadian_rhythm1.68409229
29MP0005360_urolithiasis1.67153535
30MP0004084_abnormal_cardiac_muscle1.59072204
31MP0003300_gastrointestinal_ulcer1.59051300
32MP0001485_abnormal_pinna_reflex1.56792595
33MP0005387_immune_system_phenotype1.53671736
34MP0001790_abnormal_immune_system1.53671736
35MP0005551_abnormal_eye_electrophysiolog1.51634450
36MP0004133_heterotaxia1.49780973
37MP0002234_abnormal_pharynx_morphology1.48939440
38MP0001348_abnormal_lacrimal_gland1.43682147
39MP0000427_abnormal_hair_cycle1.42012772
40MP0003880_abnormal_central_pattern1.35116408
41MP0009333_abnormal_splenocyte_physiolog1.32548556
42MP0005367_renal/urinary_system_phenotyp1.26281172
43MP0000516_abnormal_urinary_system1.26281172
44MP0003011_delayed_dark_adaptation1.22708026
45MP0005636_abnormal_mineral_homeostasis1.21691184
46MP0008057_abnormal_DNA_replication1.21063808
47MP0002138_abnormal_hepatobiliary_system1.21032995
48MP0001968_abnormal_touch/_nociception1.17059169
49MP0003938_abnormal_ear_development1.14106874
50MP0005084_abnormal_gallbladder_morpholo1.13876922
51MP0003698_abnormal_male_reproductive1.08145261
52MP0006054_spinal_hemorrhage1.07783340
53MP0001929_abnormal_gametogenesis1.07400525
54MP0003806_abnormal_nucleotide_metabolis1.07175986
55MP0009785_altered_susceptibility_to1.06709604
56MP0000604_amyloidosis1.06461349
57MP0002184_abnormal_innervation1.06078485
58MP0005332_abnormal_amino_acid1.04039443
59MP0006276_abnormal_autonomic_nervous1.02717705
60MP0001800_abnormal_humoral_immune1.02054819
61MP0003878_abnormal_ear_physiology1.01022887
62MP0005377_hearing/vestibular/ear_phenot1.01022887
63MP0001486_abnormal_startle_reflex1.00390950
64MP0001529_abnormal_vocalization0.98955465
65MP0000569_abnormal_digit_pigmentation0.98593554
66MP0005310_abnormal_salivary_gland0.92594346
67MP0005671_abnormal_response_to0.92180942
68MP0003183_abnormal_peptide_metabolism0.89481364
69MP0000490_abnormal_crypts_of0.87222586
70MP0001663_abnormal_digestive_system0.86769452
71MP0009745_abnormal_behavioral_response0.86434353
72MP0001765_abnormal_ion_homeostasis0.85033206
73MP0000049_abnormal_middle_ear0.84558316
74MP0002148_abnormal_hypersensitivity_rea0.81897619
75MP0001879_abnormal_lymphatic_vessel0.80903105
76MP0002557_abnormal_social/conspecific_i0.80082890
77MP0003077_abnormal_cell_cycle0.77189110
78MP0002736_abnormal_nociception_after0.76512544
79MP0003763_abnormal_thymus_physiology0.75270719
80MP0006036_abnormal_mitochondrial_physio0.75034348
81MP0004215_abnormal_myocardial_fiber0.74968881
82MP0002095_abnormal_skin_pigmentation0.72747949
83MP0002405_respiratory_system_inflammati0.71015898
84MP0000230_abnormal_systemic_arterial0.69221207
85MP0002210_abnormal_sex_determination0.68747580
86MP0004885_abnormal_endolymph0.68197354
87MP0003959_abnormal_lean_body0.66292533
88MP0008007_abnormal_cellular_replicative0.65906819
89MP0003693_abnormal_embryo_hatching0.65587798
90MP0009765_abnormal_xenobiotic_induced0.65372069
91MP0000653_abnormal_sex_gland0.65268741
92MP0002572_abnormal_emotion/affect_behav0.64908505
93MP0002272_abnormal_nervous_system0.64662638
94MP0005166_decreased_susceptibility_to0.64055738
95MP0008789_abnormal_olfactory_epithelium0.64020318
96MP0001501_abnormal_sleep_pattern0.63308925
97MP0002161_abnormal_fertility/fecundity0.63100942
98MP0006292_abnormal_olfactory_placode0.63019247
99MP0003186_abnormal_redox_activity0.61760688
100MP0000371_diluted_coat_color0.59730265

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)5.44150521
2Chromsome breakage (HP:0040012)5.28154183
3Microvesicular hepatic steatosis (HP:0001414)5.20494899
4Renal Fanconi syndrome (HP:0001994)4.26041952
5Duplicated collecting system (HP:0000081)4.19132273
6Lipid accumulation in hepatocytes (HP:0006561)3.91465593
7Renal cortical cysts (HP:0000803)3.91349168
8Increased hepatocellular lipid droplets (HP:0006565)3.86915847
9B lymphocytopenia (HP:0010976)3.81986826
10Tubulointerstitial nephritis (HP:0001970)3.81683961
11Abnormality of the renal collecting system (HP:0004742)3.70303487
12Pili torti (HP:0003777)3.50743393
13Hepatocellular necrosis (HP:0001404)3.47885076
14Meckel diverticulum (HP:0002245)3.45503849
15Abnormality of the ileum (HP:0001549)3.40181194
16Abnormality of B cell number (HP:0010975)3.35144501
17Pendular nystagmus (HP:0012043)3.30449820
18Reticulocytopenia (HP:0001896)3.21117780
19Increased intramyocellular lipid droplets (HP:0012240)3.19795457
20Hepatic necrosis (HP:0002605)3.17602002
21Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.10795737
22Aplasia/Hypoplasia of the uvula (HP:0010293)3.10083430
23Abnormality of DNA repair (HP:0003254)3.07626383
24Increased muscle lipid content (HP:0009058)2.97061554
25Methylmalonic aciduria (HP:0012120)2.94558259
26Fibular aplasia (HP:0002990)2.93302221
27Mitochondrial inheritance (HP:0001427)2.89925281
28Increased CSF lactate (HP:0002490)2.86809695
29Congenital, generalized hypertrichosis (HP:0004540)2.82044322
30Exertional dyspnea (HP:0002875)2.81550969
31Hyperglycinemia (HP:0002154)2.73633609
32Abnormal rod and cone electroretinograms (HP:0008323)2.68805182
33Pancreatic cysts (HP:0001737)2.67215108
34Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.66559381
35Hypoplasia of the radius (HP:0002984)2.62863508
36Increased serum pyruvate (HP:0003542)2.62002053
37Type II lissencephaly (HP:0007260)2.61583262
38Generalized aminoaciduria (HP:0002909)2.59993396
39Absent thumb (HP:0009777)2.57914023
40Severe visual impairment (HP:0001141)2.57675458
41Methylmalonic acidemia (HP:0002912)2.55647194
42Cerebellar dysplasia (HP:0007033)2.51774082
43Delayed CNS myelination (HP:0002188)2.49625510
44Hypoplastic ischia (HP:0003175)2.49479535
45Poor head control (HP:0002421)2.49420418
46Abnormality of renal resorption (HP:0011038)2.47431487
47Increased serum lactate (HP:0002151)2.47047697
48Abnormality of glycolysis (HP:0004366)2.46629553
49Absent forearm bone (HP:0003953)2.46423307
50Aplasia involving forearm bones (HP:0009822)2.46423307
51Pancytopenia (HP:0001876)2.45832840
52Hyperalaninemia (HP:0003348)2.45129021
53Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.45129021
54Abnormality of alanine metabolism (HP:0010916)2.45129021
55Cleft eyelid (HP:0000625)2.43946032
56Abnormality of the renal cortex (HP:0011035)2.42962602
57Abnormality of the preputium (HP:0100587)2.41111006
58Absent radius (HP:0003974)2.41014722
59Acute myeloid leukemia (HP:0004808)2.36788953
60Short thumb (HP:0009778)2.34890747
61Absent rod-and cone-mediated responses on ERG (HP:0007688)2.34481291
62Abnormality of chromosome stability (HP:0003220)2.32139326
63Thrombocytosis (HP:0001894)2.32090449
64Ureteral duplication (HP:0000073)2.29577078
65Large for gestational age (HP:0001520)2.29452333
66Abnormality of the pons (HP:0007361)2.28269809
67Dry hair (HP:0011359)2.28243660
68Neutropenia (HP:0001875)2.25808786
69Aplasia/Hypoplasia of the ulna (HP:0006495)2.25644338
70Pancreatic fibrosis (HP:0100732)2.24723324
71Abnormal number of erythroid precursors (HP:0012131)2.22472826
72Abnormal mitochondria in muscle tissue (HP:0008316)2.21919034
73Exercise intolerance (HP:0003546)2.20873667
74Horseshoe kidney (HP:0000085)2.18858570
75Duodenal stenosis (HP:0100867)2.15488120
76Small intestinal stenosis (HP:0012848)2.15488120
77IgG deficiency (HP:0004315)2.14848866
78Conical tooth (HP:0000698)2.14365788
79Abnormality of pyrimidine metabolism (HP:0004353)2.11598666
80Aplasia/hypoplasia of the uterus (HP:0008684)2.10618363
81Ectopic kidney (HP:0000086)2.06446296
82Stomatitis (HP:0010280)2.06357743
83Hypoplasia of the pons (HP:0012110)2.04890670
84Abnormality of the prostate (HP:0008775)2.04666801
85Abnormality of midbrain morphology (HP:0002418)2.03037072
86Molar tooth sign on MRI (HP:0002419)2.03037072
87Duplication of thumb phalanx (HP:0009942)2.02254829
88Forearm undergrowth (HP:0009821)2.01784844
89Ragged-red muscle fibers (HP:0003200)2.01643389
90Abnormality of dicarboxylic acid metabolism (HP:0010995)2.00639369
91Dicarboxylic aciduria (HP:0003215)2.00639369
92Clubbing of toes (HP:0100760)1.99390102
93Supernumerary bones of the axial skeleton (HP:0009144)1.98238140
94Tachypnea (HP:0002789)1.98018400
95Abnormality of cells of the erythroid lineage (HP:0012130)1.96911532
96Abnormality of the ischium (HP:0003174)1.96110776
97Acute necrotizing encephalopathy (HP:0006965)1.96079495
98Abnormality of urine glucose concentration (HP:0011016)1.91595599
99Glycosuria (HP:0003076)1.91595599
100Lactic acidosis (HP:0003128)1.90772685

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K24.50482695
2TXK4.44185505
3TRIM284.20972060
4INSRR3.40641359
5PIK3CG3.22358045
6PNCK2.67711395
7WEE12.55831289
8PBK2.50471456
9MAP4K12.49651120
10SRPK12.31936785
11BCKDK2.24135289
12WNK32.21706077
13MUSK2.11185666
14BUB12.10018179
15PLK42.07883586
16ZAK1.99465606
17SIK31.89934414
18EIF2AK11.84007783
19MAP3K41.77065847
20SCYL21.71595556
21TSSK61.69981084
22VRK21.49577623
23NEK91.45666253
24GRK11.43915968
25TLK11.36526147
26GRK71.35464170
27SIK21.26573240
28WNK41.23328023
29MAP2K61.20582715
30TAF11.14324847
31CDK81.13674309
32MAP2K71.13529542
33RPS6KA41.11005052
34STK41.08392071
35CDC71.04539915
36ADRBK21.02672678
37NME10.99314358
38BCR0.96512820
39PLK20.94895780
40ATR0.93819617
41VRK10.91900516
42PAK40.91545284
43TNIK0.89203819
44OXSR10.83890140
45BMPR1B0.83609646
46PINK10.83490894
47STK38L0.78739918
48MAPK130.78206993
49EPHA40.77943284
50NEK10.76326514
51STK390.74553484
52PLK10.72507447
53CAMK10.72404124
54NEK20.71119776
55BRD40.70570307
56NUAK10.69426761
57CSNK1A1L0.68839705
58TAOK30.66418356
59TESK10.65817766
60STK160.65685815
61CCNB10.63383338
62CDK40.61509730
63CSNK1G30.58899002
64DYRK20.58770977
65CAMK40.58542676
66RPS6KA50.57193348
67PLK30.56797032
68DAPK10.53262577
69MARK30.52159329
70FES0.50067588
71TTK0.49865872
72CSNK2A20.45910282
73PAK30.45334024
74BRSK20.45277085
75CSNK1G20.44633952
76CSNK2A10.40514086
77EIF2AK30.40437113
78CDK30.40202001
79DDR20.37857649
80ADRBK10.36329279
81TEC0.33935253
82AURKB0.33500993
83PRKCH0.33116117
84MAPK150.32015996
85KIT0.31302807
86CHEK10.30171489
87ATM0.28669031
88PRKCG0.28267926
89DAPK20.28076853
90BRSK10.27976634
91ZAP700.27671307
92MAPKAPK30.27471229
93MAP2K40.26432238
94GRK50.25419801
95MATK0.25349536
96ABL20.25250197
97SYK0.23844155
98CAMK2A0.22563316
99TNK20.22349740
100CSNK1G10.21861226

Predicted pathways (KEGG)

RankGene SetZ-score
1Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005633.49429601
2Proteasome_Homo sapiens_hsa030502.92555723
3Asthma_Homo sapiens_hsa053102.88977412
4DNA replication_Homo sapiens_hsa030302.79846285
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.74240036
6Mismatch repair_Homo sapiens_hsa034302.69960441
7Base excision repair_Homo sapiens_hsa034102.65321898
8Selenocompound metabolism_Homo sapiens_hsa004502.52040531
9Allograft rejection_Homo sapiens_hsa053302.50303912
10Sulfur metabolism_Homo sapiens_hsa009202.49079042
11Fanconi anemia pathway_Homo sapiens_hsa034602.43917701
12Nucleotide excision repair_Homo sapiens_hsa034202.35962312
13Homologous recombination_Homo sapiens_hsa034402.35759478
14Intestinal immune network for IgA production_Homo sapiens_hsa046722.33275264
15Autoimmune thyroid disease_Homo sapiens_hsa053202.28109345
16Basal transcription factors_Homo sapiens_hsa030222.23636997
17Protein export_Homo sapiens_hsa030602.19785809
18RNA polymerase_Homo sapiens_hsa030202.16602141
19Ribosome_Homo sapiens_hsa030102.07884722
20Pyrimidine metabolism_Homo sapiens_hsa002402.07153999
21Oxidative phosphorylation_Homo sapiens_hsa001902.04001958
22Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.94109465
23Nitrogen metabolism_Homo sapiens_hsa009101.82236818
24Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.75954852
25Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.73041494
26Sulfur relay system_Homo sapiens_hsa041221.69884507
27Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.66448455
28Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.52832856
29Parkinsons disease_Homo sapiens_hsa050121.49198709
30Folate biosynthesis_Homo sapiens_hsa007901.48332176
31Caffeine metabolism_Homo sapiens_hsa002321.26028335
32Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.21417664
33Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.12188184
34Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.11991022
35Jak-STAT signaling pathway_Homo sapiens_hsa046301.11832800
36Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.10218829
37T cell receptor signaling pathway_Homo sapiens_hsa046601.09278455
38One carbon pool by folate_Homo sapiens_hsa006701.08481356
39Type I diabetes mellitus_Homo sapiens_hsa049401.06977258
40Phototransduction_Homo sapiens_hsa047441.06618553
412-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.05214470
42Huntingtons disease_Homo sapiens_hsa050161.04845240
43Spliceosome_Homo sapiens_hsa030401.02593987
44Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.01933882
45Vitamin B6 metabolism_Homo sapiens_hsa007500.99631928
46Purine metabolism_Homo sapiens_hsa002300.98027400
47Graft-versus-host disease_Homo sapiens_hsa053320.96465901
48Non-homologous end-joining_Homo sapiens_hsa034500.96339054
49Hematopoietic cell lineage_Homo sapiens_hsa046400.95175749
50RNA transport_Homo sapiens_hsa030130.93828615
51Cysteine and methionine metabolism_Homo sapiens_hsa002700.92561252
52Cardiac muscle contraction_Homo sapiens_hsa042600.92436850
53Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.91945720
54Tryptophan metabolism_Homo sapiens_hsa003800.89748963
55Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.88508041
56Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.87967397
57Olfactory transduction_Homo sapiens_hsa047400.80001559
58Alzheimers disease_Homo sapiens_hsa050100.78095130
59Circadian rhythm_Homo sapiens_hsa047100.77766278
60Peroxisome_Homo sapiens_hsa041460.75933713
61Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.73979629
62Arginine biosynthesis_Homo sapiens_hsa002200.67255220
63Arginine and proline metabolism_Homo sapiens_hsa003300.67234981
64RNA degradation_Homo sapiens_hsa030180.64759144
65Nicotine addiction_Homo sapiens_hsa050330.63058370
66Steroid hormone biosynthesis_Homo sapiens_hsa001400.62978321
67Metabolic pathways_Homo sapiens_hsa011000.61259538
68Biosynthesis of amino acids_Homo sapiens_hsa012300.59187939
69Fatty acid biosynthesis_Homo sapiens_hsa000610.58724373
70Regulation of autophagy_Homo sapiens_hsa041400.56882861
71Linoleic acid metabolism_Homo sapiens_hsa005910.55407139
72Mineral absorption_Homo sapiens_hsa049780.53907758
73Transcriptional misregulation in cancer_Homo sapiens_hsa052020.53248310
74Retinol metabolism_Homo sapiens_hsa008300.51828102
75Primary immunodeficiency_Homo sapiens_hsa053400.46421543
76Taste transduction_Homo sapiens_hsa047420.45274403
77Propanoate metabolism_Homo sapiens_hsa006400.43857165
78Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.40977670
79Glutathione metabolism_Homo sapiens_hsa004800.39375251
80Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.32821112
81Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.28792924
82Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.27623209
83Salivary secretion_Homo sapiens_hsa049700.27307579
84Antigen processing and presentation_Homo sapiens_hsa046120.26907331
85Maturity onset diabetes of the young_Homo sapiens_hsa049500.26278196
86Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.24073649
87Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.21485005
88Fatty acid elongation_Homo sapiens_hsa000620.21465519
89Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.21374277
90Renin-angiotensin system_Homo sapiens_hsa046140.20894981
91Chemical carcinogenesis_Homo sapiens_hsa052040.19143689
92Protein digestion and absorption_Homo sapiens_hsa049740.15804056
93Epstein-Barr virus infection_Homo sapiens_hsa051690.15767887
94Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.15532401
95Butanoate metabolism_Homo sapiens_hsa006500.15484781
96ABC transporters_Homo sapiens_hsa020100.13868283
97Systemic lupus erythematosus_Homo sapiens_hsa053220.13184233
98Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.10607081
99mRNA surveillance pathway_Homo sapiens_hsa030150.06944584
100Measles_Homo sapiens_hsa051620.06710988

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »