NUTF2P7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1lactate metabolic process (GO:0006089)6.98345140
2proteasome assembly (GO:0043248)5.75487187
3activated T cell proliferation (GO:0050798)5.68833777
4protein-cofactor linkage (GO:0018065)5.49807319
5serotonin metabolic process (GO:0042428)4.84991948
6peptidyl-histidine modification (GO:0018202)4.79295170
7positive regulation of immune response to tumor cell (GO:0002839)4.70405444
8regulation of immune response to tumor cell (GO:0002837)4.70405444
9regulation of response to tumor cell (GO:0002834)4.70405444
10positive regulation of response to tumor cell (GO:0002836)4.70405444
11regulation of interferon-beta biosynthetic process (GO:0045357)4.53377563
12lung lobe morphogenesis (GO:0060463)4.43013516
13water-soluble vitamin biosynthetic process (GO:0042364)4.21010685
14primary amino compound metabolic process (GO:1901160)4.15689675
15regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)4.00587562
16regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)3.97927592
17response to interferon-beta (GO:0035456)3.96371316
18cellular response to interferon-beta (GO:0035458)3.88762252
19protein deneddylation (GO:0000338)3.88364102
20platelet dense granule organization (GO:0060155)3.83619797
21establishment of protein localization to mitochondrial membrane (GO:0090151)3.81999601
22chaperone-mediated protein transport (GO:0072321)3.77833609
23regulation of RIG-I signaling pathway (GO:0039535)3.71841366
24respiratory chain complex IV assembly (GO:0008535)3.70946584
25cullin deneddylation (GO:0010388)3.63953367
26positive regulation of T cell chemotaxis (GO:0010820)3.59334775
27regulation of T cell chemotaxis (GO:0010819)3.59334775
28cytokine biosynthetic process (GO:0042089)3.59118454
29regulation of G0 to G1 transition (GO:0070316)3.54154385
30protein neddylation (GO:0045116)3.52184738
31cellular response to dsRNA (GO:0071359)3.51594395
32modulation by symbiont of host immune response (GO:0052553)3.43516064
33positive regulation by symbiont of host defense response (GO:0052509)3.43516064
34modulation by symbiont of host defense response (GO:0052031)3.43516064
35modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.43516064
36modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.43516064
37positive regulation by organism of defense response of other organism involved in symbiotic interact3.43516064
38cellular response to exogenous dsRNA (GO:0071360)3.43343834
39cornea development in camera-type eye (GO:0061303)3.42486560
40NIK/NF-kappaB signaling (GO:0038061)3.42314090
41positive regulation of NF-kappaB import into nucleus (GO:0042346)3.42003194
42indolalkylamine metabolic process (GO:0006586)3.35256549
43detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.35028182
44hepatocyte apoptotic process (GO:0097284)3.33038940
45response to xenobiotic stimulus (GO:0009410)3.27935740
46positive regulation of chemokine biosynthetic process (GO:0045080)3.23182767
47GTP biosynthetic process (GO:0006183)3.19118897
48cytochrome complex assembly (GO:0017004)3.18962706
49phosphatidylserine acyl-chain remodeling (GO:0036150)3.16224670
50pseudouridine synthesis (GO:0001522)3.14118711
51necroptotic process (GO:0070266)3.13383623
52negative regulation of reactive oxygen species metabolic process (GO:2000378)3.09481750
53monoubiquitinated protein deubiquitination (GO:0035520)3.09464788
54Arp2/3 complex-mediated actin nucleation (GO:0034314)3.08572676
55T cell apoptotic process (GO:0070231)3.08198086
56regulation of sister chromatid cohesion (GO:0007063)3.02131773
57mitochondrial respiratory chain complex assembly (GO:0033108)3.00404107
58indole-containing compound metabolic process (GO:0042430)2.99435292
59response to host immune response (GO:0052572)2.98785628
60response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.98785628
61regulation of Golgi to plasma membrane protein transport (GO:0042996)2.96184743
62lymphocyte apoptotic process (GO:0070227)2.95084219
63positive regulation of protein homooligomerization (GO:0032464)2.94280803
64regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)2.87434297
65calcium-mediated signaling using intracellular calcium source (GO:0035584)2.86603738
66negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.85863360
67negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)2.84905909
68cytokine metabolic process (GO:0042107)2.84760192
69positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)2.84456077
70meiotic chromosome segregation (GO:0045132)2.83887212
71mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.78231813
72DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.76988172
73actin nucleation (GO:0045010)2.74451999
74mitochondrial respiratory chain complex I assembly (GO:0032981)2.74165501
75NADH dehydrogenase complex assembly (GO:0010257)2.74165501
76mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.74165501
77rRNA modification (GO:0000154)2.73083261
78negative regulation of necroptotic process (GO:0060546)2.72886121
79DNA deamination (GO:0045006)2.72735712
80regulation of cellular amino acid metabolic process (GO:0006521)2.72436225
81type B pancreatic cell proliferation (GO:0044342)2.72367267
82glycine transport (GO:0015816)2.72241845
83establishment of integrated proviral latency (GO:0075713)2.71973872
84regulation of acyl-CoA biosynthetic process (GO:0050812)2.71605779
85microglial cell activation (GO:0001774)2.71129910
86protein complex biogenesis (GO:0070271)2.70999068
87cellular response to lithium ion (GO:0071285)2.70449636
88positive regulation of mitotic sister chromatid separation (GO:1901970)2.70135990
89positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.70135990
90positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.70135990
91purine nucleoside triphosphate biosynthetic process (GO:0009145)2.66585022
92purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.66565576
93positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.65183444
94negative regulation of systemic arterial blood pressure (GO:0003085)2.64964790
95intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.64887014
96signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.64887014
97ATP synthesis coupled proton transport (GO:0015986)2.64679693
98energy coupled proton transport, down electrochemical gradient (GO:0015985)2.64679693
99antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.64071603
100regulation of cofactor metabolic process (GO:0051193)2.62613430

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse5.55861340
2RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse5.03167432
3VDR_22108803_ChIP-Seq_LS180_Human4.28986867
4GABP_17652178_ChIP-ChIP_JURKAT_Human3.58579261
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.18081992
6IGF1R_20145208_ChIP-Seq_DFB_Human3.02012397
7ZNF274_21170338_ChIP-Seq_K562_Hela3.01543011
8EST1_17652178_ChIP-ChIP_JURKAT_Human2.68377769
9ELK1_19687146_ChIP-ChIP_HELA_Human2.58991924
10JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.38220100
11HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.34262916
12CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.27735078
13BCAT_22108803_ChIP-Seq_LS180_Human2.20317252
14IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.17653659
15GBX2_23144817_ChIP-Seq_PC3_Human2.14399347
16EWS_26573619_Chip-Seq_HEK293_Human2.06602365
17GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.03547016
18IRF8_21731497_ChIP-ChIP_J774_Mouse2.03048501
19ZFP57_27257070_Chip-Seq_ESCs_Mouse1.94601143
20NOTCH1_21737748_ChIP-Seq_TLL_Human1.78624924
21NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.78199475
22FLI1_27457419_Chip-Seq_LIVER_Mouse1.77361114
23P300_19829295_ChIP-Seq_ESCs_Human1.75440654
24BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.72832436
25SALL1_21062744_ChIP-ChIP_HESCs_Human1.72094193
26UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.69688597
27VDR_23849224_ChIP-Seq_CD4+_Human1.68878147
28ETS1_20019798_ChIP-Seq_JURKAT_Human1.66220289
29SMAD_19615063_ChIP-ChIP_OVARY_Human1.58225288
30STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.54549742
31POU5F1_16153702_ChIP-ChIP_HESCs_Human1.48668117
32TCF4_22108803_ChIP-Seq_LS180_Human1.45032871
33POU3F2_20337985_ChIP-ChIP_501MEL_Human1.40777438
34EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.38578881
35MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.36983756
36SRF_21415370_ChIP-Seq_HL-1_Mouse1.36977086
37FOXA1_25329375_ChIP-Seq_VCAP_Human1.31239428
38FOXA1_27270436_Chip-Seq_PROSTATE_Human1.31239428
39CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.28037744
40TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.27726018
41FUS_26573619_Chip-Seq_HEK293_Human1.25311213
42HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.24358519
43TAF15_26573619_Chip-Seq_HEK293_Human1.24101064
44AR_20517297_ChIP-Seq_VCAP_Human1.21682381
45MYC_18940864_ChIP-ChIP_HL60_Human1.21398561
46TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.20797725
47FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.20211282
48IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.18687564
49PCGF2_27294783_Chip-Seq_ESCs_Mouse1.18666861
50AUTS2_25519132_ChIP-Seq_293T-REX_Human1.18508202
51CTBP2_25329375_ChIP-Seq_LNCAP_Human1.17039047
52CTBP1_25329375_ChIP-Seq_LNCAP_Human1.14311268
53KLF5_20875108_ChIP-Seq_MESCs_Mouse1.13857035
54CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.13122085
55IRF8_22096565_ChIP-ChIP_GC-B_Human1.12577572
56CDX2_22108803_ChIP-Seq_LS180_Human1.11598354
57CBP_20019798_ChIP-Seq_JUKART_Human1.11365200
58IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.11365200
59NFE2_27457419_Chip-Seq_LIVER_Mouse1.10484161
60PCGF2_27294783_Chip-Seq_NPCs_Mouse1.07930828
61MYC_18555785_ChIP-Seq_MESCs_Mouse1.07624234
62POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.07358387
63TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07358387
64SMAD4_21741376_ChIP-Seq_EPCs_Human1.06284645
65CREB1_15753290_ChIP-ChIP_HEK293T_Human1.05880897
66GATA3_26560356_Chip-Seq_TH2_Human1.05654143
67SOX2_19829295_ChIP-Seq_ESCs_Human1.05325780
68NANOG_19829295_ChIP-Seq_ESCs_Human1.05325780
69FOXP3_21729870_ChIP-Seq_TREG_Human1.04930312
70OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.03457706
71STAT3_18555785_Chip-Seq_ESCs_Mouse1.03362466
72FOXA1_21572438_ChIP-Seq_LNCaP_Human1.01759059
73HOXB4_20404135_ChIP-ChIP_EML_Mouse1.01019797
74FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.00294381
75ER_23166858_ChIP-Seq_MCF-7_Human0.99352857
76LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.99174694
77FOXH1_21741376_ChIP-Seq_EPCs_Human0.98793812
78ELF5_23300383_ChIP-Seq_T47D_Human0.98138085
79SUZ12_27294783_Chip-Seq_NPCs_Mouse0.97947105
80CBP_21632823_ChIP-Seq_H3396_Human0.96571799
81STAT4_19710469_ChIP-ChIP_TH1__Mouse0.96542254
82HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.95803181
83PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.95661349
84HOXB7_26014856_ChIP-Seq_BT474_Human0.95459110
85MYC_19829295_ChIP-Seq_ESCs_Human0.95079946
86GATA2_21666600_ChIP-Seq_HMVEC_Human0.94247383
87EZH2_27294783_Chip-Seq_NPCs_Mouse0.92166016
88MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.91815054
89RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.91090304
90TP53_22573176_ChIP-Seq_HFKS_Human0.90528161
91STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.89950060
92SALL4_22934838_ChIP-ChIP_CD34+_Human0.89443638
93PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.89164513
94SUZ12_18555785_Chip-Seq_ESCs_Mouse0.88841482
95SMAD4_21799915_ChIP-Seq_A2780_Human0.87305735
96SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.86745951
97PRDM14_20953172_ChIP-Seq_ESCs_Human0.85421965
98AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.84360630
99GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.84071274
100RUNX1_27457419_Chip-Seq_LIVER_Mouse0.83820526

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006054_spinal_hemorrhage4.53030802
2MP0003787_abnormal_imprinting2.95898336
3MP0005167_abnormal_blood-brain_barrier2.80574958
4MP0000465_gastrointestinal_hemorrhage2.77987334
5MP0006072_abnormal_retinal_apoptosis2.58695638
6MP0005671_abnormal_response_to2.49673909
7MP0002163_abnormal_gland_morphology2.32764965
8MP0000372_irregular_coat_pigmentation2.31197098
9MP0002102_abnormal_ear_morphology2.29381043
10MP0001835_abnormal_antigen_presentation2.23049308
11MP0001879_abnormal_lymphatic_vessel2.16507625
12MP0004147_increased_porphyrin_level2.14851560
13MP0005253_abnormal_eye_physiology2.10867712
14MP0005165_increased_susceptibility_to2.08185850
15MP0008877_abnormal_DNA_methylation2.07986289
16MP0010368_abnormal_lymphatic_system2.04338006
17MP0001346_abnormal_lacrimal_gland2.01219239
18MP0001764_abnormal_homeostasis2.01198074
19MP0009333_abnormal_splenocyte_physiolog1.98962360
20MP0008007_abnormal_cellular_replicative1.94526228
21MP0001873_stomach_inflammation1.91901053
22MP0003186_abnormal_redox_activity1.85974921
23MP0003195_calcinosis1.76314879
24MP0001348_abnormal_lacrimal_gland1.75863637
25MP0003693_abnormal_embryo_hatching1.71658619
26MP0005551_abnormal_eye_electrophysiolog1.69708849
27MP0001790_abnormal_immune_system1.67529859
28MP0005387_immune_system_phenotype1.67529859
29MP0005379_endocrine/exocrine_gland_phen1.67512902
30MP0004885_abnormal_endolymph1.63759979
31MP0004142_abnormal_muscle_tone1.62472368
32MP0002877_abnormal_melanocyte_morpholog1.59823199
33MP0005083_abnormal_biliary_tract1.59096718
34MP0001968_abnormal_touch/_nociception1.55487450
35MP0004145_abnormal_muscle_electrophysio1.52901039
36MP0004957_abnormal_blastocyst_morpholog1.52771257
37MP0002876_abnormal_thyroid_physiology1.52388641
38MP0005084_abnormal_gallbladder_morpholo1.52302029
39MP0003656_abnormal_erythrocyte_physiolo1.49361424
40MP0002736_abnormal_nociception_after1.47779450
41MP0004215_abnormal_myocardial_fiber1.46496903
42MP0004484_altered_response_of1.44991827
43MP0005075_abnormal_melanosome_morpholog1.44384744
44MP0006082_CNS_inflammation1.44205342
45MP0006036_abnormal_mitochondrial_physio1.37949656
46MP0003646_muscle_fatigue1.33673556
47MP0008775_abnormal_heart_ventricle1.32733212
48MP0002254_reproductive_system_inflammat1.26939642
49MP0004084_abnormal_cardiac_muscle1.26433725
50MP0008058_abnormal_DNA_repair1.17689092
51MP0002138_abnormal_hepatobiliary_system1.12381348
52MP0005360_urolithiasis1.11231285
53MP0001800_abnormal_humoral_immune1.10633038
54MP0002723_abnormal_immune_serum1.09779698
55MP0002396_abnormal_hematopoietic_system1.08520666
56MP0002148_abnormal_hypersensitivity_rea1.06540007
57MP0000647_abnormal_sebaceous_gland1.04818834
58MP0008875_abnormal_xenobiotic_pharmacok1.03564251
59MP0009053_abnormal_anal_canal1.01561662
60MP0002452_abnormal_antigen_presenting1.01299256
61MP0001191_abnormal_skin_condition0.97219961
62MP0003136_yellow_coat_color0.97089174
63MP0005389_reproductive_system_phenotype0.96522464
64MP0005410_abnormal_fertilization0.94836096
65MP0004742_abnormal_vestibular_system0.94574953
66MP0008057_abnormal_DNA_replication0.93854621
67MP0009697_abnormal_copulation0.93838393
68MP0004036_abnormal_muscle_relaxation0.92445323
69MP0010094_abnormal_chromosome_stability0.91305720
70MP0006276_abnormal_autonomic_nervous0.90681969
71MP0004134_abnormal_chest_morphology0.88805054
72MP0003943_abnormal_hepatobiliary_system0.86608932
73MP0005595_abnormal_vascular_smooth0.86433970
74MP0003315_abnormal_perineum_morphology0.85953333
75MP0009764_decreased_sensitivity_to0.85613043
76MP0005408_hypopigmentation0.84681036
77MP0000749_muscle_degeneration0.82837145
78MP0005670_abnormal_white_adipose0.79525342
79MP0003252_abnormal_bile_duct0.79153869
80MP0008872_abnormal_physiological_respon0.78171192
81MP0000685_abnormal_immune_system0.77995131
82MP0001544_abnormal_cardiovascular_syste0.77392029
83MP0005385_cardiovascular_system_phenoty0.77392029
84MP0002420_abnormal_adaptive_immunity0.76804159
85MP0002419_abnormal_innate_immunity0.76709376
86MP0005187_abnormal_penis_morphology0.75903701
87MP0000015_abnormal_ear_pigmentation0.75747243
88MP0001919_abnormal_reproductive_system0.75651264
89MP0001819_abnormal_immune_cell0.74934957
90MP0005171_absent_coat_pigmentation0.73427528
91MP0003638_abnormal_response/metabolism_0.73125342
92MP0001529_abnormal_vocalization0.72835853
93MP0004272_abnormal_basement_membrane0.71775959
94MP0005195_abnormal_posterior_eye0.71399795
95MP0001986_abnormal_taste_sensitivity0.70614417
96MP0009046_muscle_twitch0.70034503
97MP0002090_abnormal_vision0.69064600
98MP0005647_abnormal_sex_gland0.68218731
99MP0002837_dystrophic_cardiac_calcinosis0.68001722
100MP0004019_abnormal_vitamin_homeostasis0.65610572

Predicted human phenotypes

RankGene SetZ-score
1Increased IgM level (HP:0003496)4.49812220
2Abnormal delayed hypersensitivity skin test (HP:0002963)3.84440409
3Acute necrotizing encephalopathy (HP:0006965)3.57316450
4Acute encephalopathy (HP:0006846)3.43608036
5Hyperlipoproteinemia (HP:0010980)3.39185596
6Autoimmune thrombocytopenia (HP:0001973)3.31008857
7Short tibia (HP:0005736)3.26126681
8Pancreatic fibrosis (HP:0100732)3.26046386
9Long clavicles (HP:0000890)3.18299954
10Cerebral hemorrhage (HP:0001342)2.98434148
11Progressive macrocephaly (HP:0004481)2.97214429
12Aplasia/Hypoplasia of the tibia (HP:0005772)2.95652552
13Abnormal mitochondria in muscle tissue (HP:0008316)2.94216349
14Abnormality of T cell physiology (HP:0011840)2.89680324
15Volvulus (HP:0002580)2.84832866
16Microglossia (HP:0000171)2.82848159
17Median cleft lip (HP:0000161)2.73106356
18Reduced antithrombin III activity (HP:0001976)2.69465662
19Autoimmune hemolytic anemia (HP:0001890)2.63722352
20Large eyes (HP:0001090)2.63703239
21Absent rod-and cone-mediated responses on ERG (HP:0007688)2.63410711
22Constricted visual fields (HP:0001133)2.61812969
23Vitreoretinal degeneration (HP:0000655)2.56639906
24Progressive inability to walk (HP:0002505)2.55214695
25Abnormality of alanine metabolism (HP:0010916)2.54127923
26Hyperalaninemia (HP:0003348)2.54127923
27Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.54127923
28Degeneration of anterior horn cells (HP:0002398)2.48281014
29Abnormality of the anterior horn cell (HP:0006802)2.48281014
30Cerebral edema (HP:0002181)2.46702490
31Abnormality of midbrain morphology (HP:0002418)2.46532303
32Molar tooth sign on MRI (HP:0002419)2.46532303
33Optic disc pallor (HP:0000543)2.45081510
34Dyschromatopsia (HP:0007641)2.44430425
35Stenosis of the external auditory canal (HP:0000402)2.44376138
36Pancreatic cysts (HP:0001737)2.42939951
37Mitochondrial inheritance (HP:0001427)2.40963864
38Abnormal protein glycosylation (HP:0012346)2.37604786
39Abnormal glycosylation (HP:0012345)2.37604786
40Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.37604786
41Abnormal protein N-linked glycosylation (HP:0012347)2.37604786
42Short 4th metacarpal (HP:0010044)2.36354363
43Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.36354363
44Increased CSF lactate (HP:0002490)2.35982964
45Lactic acidosis (HP:0003128)2.33988167
46Abnormal finger flexion creases (HP:0006143)2.33552230
47Abnormality of chromosome segregation (HP:0002916)2.30033432
48Aplasia/Hypoplasia of the tongue (HP:0010295)2.25950935
49Eosinophilia (HP:0001880)2.22422810
5011 pairs of ribs (HP:0000878)2.21130442
51Pancreatic islet-cell hyperplasia (HP:0004510)2.18840481
52Pulmonary infiltrates (HP:0002113)2.18382876
53Inability to walk (HP:0002540)2.18210887
54Hypochromic anemia (HP:0001931)2.18120518
55Increased serum lactate (HP:0002151)2.17813972
56Decreased electroretinogram (ERG) amplitude (HP:0000654)2.17336978
57Abnormal lung lobation (HP:0002101)2.15002959
58Keratoconus (HP:0000563)2.14891475
59Increased corneal curvature (HP:0100692)2.14891475
60Type I transferrin isoform profile (HP:0003642)2.14589690
61Severe muscular hypotonia (HP:0006829)2.10983383
62Fatigue (HP:0012378)2.08678387
63Hypoalphalipoproteinemia (HP:0003233)2.07690526
643-Methylglutaconic aciduria (HP:0003535)2.04473964
65Attenuation of retinal blood vessels (HP:0007843)2.01557109
66Chronic otitis media (HP:0000389)2.00626432
67Myocardial infarction (HP:0001658)1.98732423
68Hepatocellular necrosis (HP:0001404)1.98185858
69Central scotoma (HP:0000603)1.97759460
70Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.97728451
71Metaphyseal dysplasia (HP:0100255)1.96279219
72Chronic sinusitis (HP:0011109)1.96230082
73Entropion (HP:0000621)1.95475862
74Hypoproteinemia (HP:0003075)1.94139274
75Absent/shortened dynein arms (HP:0200106)1.93682221
76Dynein arm defect of respiratory motile cilia (HP:0012255)1.93682221
77Congenital ichthyosiform erythroderma (HP:0007431)1.93324878
78IgG deficiency (HP:0004315)1.93294350
79Exertional dyspnea (HP:0002875)1.92248584
80Scotoma (HP:0000575)1.91617648
81Abnormality of the renal cortex (HP:0011035)1.89914227
82True hermaphroditism (HP:0010459)1.88801993
83Abnormality of the renal medulla (HP:0100957)1.81596263
84Leukodystrophy (HP:0002415)1.80877736
85Abnormality of T cells (HP:0002843)1.79516056
86Spinal muscular atrophy (HP:0007269)1.78184691
87Submucous cleft hard palate (HP:0000176)1.76475925
88Wide intermamillary distance (HP:0006610)1.76342739
89Anencephaly (HP:0002323)1.75749784
90Abnormality of T cell number (HP:0011839)1.74721635
91Large for gestational age (HP:0001520)1.74621481
92Chronic hepatic failure (HP:0100626)1.74393970
93Parakeratosis (HP:0001036)1.73434031
94Abnormal foot bone ossification (HP:0010675)1.73287556
95Breast carcinoma (HP:0003002)1.72502476
96Ectopic kidney (HP:0000086)1.72354315
97Abnormality of the prostate (HP:0008775)1.70950983
98Nephronophthisis (HP:0000090)1.70490826
99Prostate neoplasm (HP:0100787)1.68612507
100Generalized tonic-clonic seizures (HP:0002069)1.67409880

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MST44.47780414
2TIE14.12060777
3VRK24.02176570
4ACVR1B3.99669775
5MAP3K123.65973822
6BCR3.36863224
7NUAK12.51292694
8TXK2.15945258
9TAF11.95650968
10TEC1.83111581
11TGFBR21.78685948
12RPS6KA41.78190799
13KSR11.70131929
14MYLK1.63492081
15MARK31.52335423
16VRK11.50513763
17BMPR1B1.41882522
18FER1.41210961
19STK161.39313034
20PAK41.38740632
21CSNK1G31.38307636
22GRK11.31833474
23WNK41.26214354
24HIPK21.25243349
25GRK61.22863973
26TRIM281.21304852
27CSNK1A1L1.16938370
28ADRBK21.16314314
29STK391.14261569
30SRPK11.14220414
31FRK1.13695955
32PTK2B1.12883668
33CSNK1G11.11557991
34NEK11.09850821
35DAPK11.09323713
36CCNB11.08915855
37ERBB31.08588864
38FES1.07173137
39TLK11.06403571
40BUB11.02772551
41ARAF1.01057600
42CDK30.99581658
43CSNK1G20.98944383
44OXSR10.96802597
45SCYL20.95527834
46BLK0.92389271
47BCKDK0.91227538
48TYK20.90172408
49PLK30.89857623
50NTRK30.87875603
51MAPK130.87134600
52CLK10.86677477
53MAP3K80.83395834
54RAF10.80992995
55PRKCE0.80320149
56MAP3K20.80185022
57GRK50.79838520
58MINK10.79199804
59SIK30.76057892
60ILK0.75882188
61PDK20.73028652
62KDR0.72899588
63MAPKAPK50.71443337
64PINK10.69537966
65EPHB10.68460174
66EPHB20.67746616
67LIMK10.67404696
68MAP3K30.64596665
69TSSK60.62826779
70EIF2AK10.62703549
71EIF2AK30.61918894
72MUSK0.61792455
73DAPK30.57373213
74DYRK20.55608880
75PRKCI0.54595169
76DYRK30.50178497
77AURKB0.47429839
78NME20.45681320
79CDK90.45542574
80PLK20.42354605
81PAK30.42019312
82RPS6KA50.41061192
83CSNK1A10.40795596
84INSRR0.39705966
85ERBB40.39672661
86IKBKB0.37744239
87KSR20.33179874
88ATR0.31382851
89MAPKAPK20.31229131
90PIK3CA0.29543634
91STK100.29208768
92CAMK2G0.29132029
93EIF2AK20.25388261
94SMG10.25058189
95ERBB20.24333621
96PBK0.24110247
97WEE10.22787445
98CAMK1D0.22278323
99CDK80.21931060
100IGF1R0.21633340

Predicted pathways (KEGG)

RankGene SetZ-score
1Asthma_Homo sapiens_hsa053104.06711305
2Proteasome_Homo sapiens_hsa030504.02968074
3Fatty acid elongation_Homo sapiens_hsa000623.36017883
4Allograft rejection_Homo sapiens_hsa053303.25089606
5Autoimmune thyroid disease_Homo sapiens_hsa053203.11267448
6Graft-versus-host disease_Homo sapiens_hsa053323.10038733
7Non-homologous end-joining_Homo sapiens_hsa034502.86629028
8Intestinal immune network for IgA production_Homo sapiens_hsa046722.62629510
9Type I diabetes mellitus_Homo sapiens_hsa049402.36728298
10Oxidative phosphorylation_Homo sapiens_hsa001902.22101527
11Propanoate metabolism_Homo sapiens_hsa006402.12056744
12Antigen processing and presentation_Homo sapiens_hsa046121.99168842
13Pyruvate metabolism_Homo sapiens_hsa006201.86394427
14Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.75905253
15Rheumatoid arthritis_Homo sapiens_hsa053231.74936624
16Protein export_Homo sapiens_hsa030601.70092689
17Parkinsons disease_Homo sapiens_hsa050121.69090114
18Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.59909857
19Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.59523664
20Homologous recombination_Homo sapiens_hsa034401.50363358
21Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.46434237
22Viral myocarditis_Homo sapiens_hsa054161.43679157
23RNA polymerase_Homo sapiens_hsa030201.43653261
24Tryptophan metabolism_Homo sapiens_hsa003801.40610430
25Collecting duct acid secretion_Homo sapiens_hsa049661.37976068
26Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.34330295
27Mismatch repair_Homo sapiens_hsa034301.27879307
28N-Glycan biosynthesis_Homo sapiens_hsa005101.26634133
29Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.25991499
30Alzheimers disease_Homo sapiens_hsa050101.20889541
31Huntingtons disease_Homo sapiens_hsa050161.20691181
32Fanconi anemia pathway_Homo sapiens_hsa034601.18106213
33Nucleotide excision repair_Homo sapiens_hsa034201.18088612
34Nitrogen metabolism_Homo sapiens_hsa009101.15592162
35Staphylococcus aureus infection_Homo sapiens_hsa051501.14902351
36SNARE interactions in vesicular transport_Homo sapiens_hsa041301.14387493
37Glutathione metabolism_Homo sapiens_hsa004801.12393120
38Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.09271537
39Fat digestion and absorption_Homo sapiens_hsa049751.07595008
40Fatty acid metabolism_Homo sapiens_hsa012121.06742019
41Cysteine and methionine metabolism_Homo sapiens_hsa002701.04866466
42Steroid biosynthesis_Homo sapiens_hsa001001.02997661
43Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.98495001
44Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.91351872
45Hematopoietic cell lineage_Homo sapiens_hsa046400.89263738
46Cyanoamino acid metabolism_Homo sapiens_hsa004600.82350028
47Phototransduction_Homo sapiens_hsa047440.80775537
48Toxoplasmosis_Homo sapiens_hsa051450.80360520
49Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.80086753
50Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.78851961
51Pyrimidine metabolism_Homo sapiens_hsa002400.76733437
52Chemical carcinogenesis_Homo sapiens_hsa052040.71714687
53Primary immunodeficiency_Homo sapiens_hsa053400.70306138
54Basal transcription factors_Homo sapiens_hsa030220.69059013
55Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.68851025
56alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.65794218
57Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.65028027
58Linoleic acid metabolism_Homo sapiens_hsa005910.63769207
59Drug metabolism - other enzymes_Homo sapiens_hsa009830.63186790
60Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.62658092
61Renin-angiotensin system_Homo sapiens_hsa046140.61599991
62Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.61325556
63Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.60576956
64Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.59919319
65Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.58585139
66One carbon pool by folate_Homo sapiens_hsa006700.58385465
67Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.57540918
68Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.56209098
69Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.56178050
70Glycerolipid metabolism_Homo sapiens_hsa005610.55427340
71Olfactory transduction_Homo sapiens_hsa047400.55394048
72Herpes simplex infection_Homo sapiens_hsa051680.55319772
73Influenza A_Homo sapiens_hsa051640.55296866
74Purine metabolism_Homo sapiens_hsa002300.53793264
75Butanoate metabolism_Homo sapiens_hsa006500.53582938
76Steroid hormone biosynthesis_Homo sapiens_hsa001400.53520405
77Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.52253574
78Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.51465738
79Salivary secretion_Homo sapiens_hsa049700.50768608
80NOD-like receptor signaling pathway_Homo sapiens_hsa046210.50717035
81Ribosome_Homo sapiens_hsa030100.48710664
82Cardiac muscle contraction_Homo sapiens_hsa042600.46803848
83Metabolic pathways_Homo sapiens_hsa011000.44128383
84Epstein-Barr virus infection_Homo sapiens_hsa051690.43329976
85Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.42808895
86Selenocompound metabolism_Homo sapiens_hsa004500.42125290
87Phagosome_Homo sapiens_hsa041450.41767155
88Tuberculosis_Homo sapiens_hsa051520.35194735
89Vibrio cholerae infection_Homo sapiens_hsa051100.34459283
90Leishmaniasis_Homo sapiens_hsa051400.32687321
91Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.32374734
92Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.31522789
93Sulfur metabolism_Homo sapiens_hsa009200.31099455
94Pentose and glucuronate interconversions_Homo sapiens_hsa000400.30764741
95Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.30328948
96Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.30130596
97Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.28147178
98Retinol metabolism_Homo sapiens_hsa008300.27750559
99RNA transport_Homo sapiens_hsa030130.27184233
100Pancreatic secretion_Homo sapiens_hsa049720.25452301

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »