NUTM1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cell wall macromolecule catabolic process (GO:0016998)9.89981306
2cell wall macromolecule metabolic process (GO:0044036)9.89981306
3cilium or flagellum-dependent cell motility (GO:0001539)9.60306169
4multicellular organism reproduction (GO:0032504)9.52941449
5sperm-egg recognition (GO:0035036)9.47241972
6acrosome assembly (GO:0001675)9.07590090
7acrosome reaction (GO:0007340)9.02569690
8plasma membrane fusion (GO:0045026)8.98573735
9male meiosis (GO:0007140)8.82689760
10synaptonemal complex assembly (GO:0007130)8.75245254
11synaptonemal complex organization (GO:0070193)8.71512042
12meiotic chromosome segregation (GO:0045132)8.68496290
13binding of sperm to zona pellucida (GO:0007339)8.58909011
14axonemal dynein complex assembly (GO:0070286)8.52676441
15cell-cell recognition (GO:0009988)8.44262079
16spermatid development (GO:0007286)8.23747357
17epithelial cilium movement (GO:0003351)8.11412827
18DNA methylation involved in gamete generation (GO:0043046)7.89408481
19reproduction (GO:0000003)7.84792626
20motile cilium assembly (GO:0044458)7.77411912
21regulation of cilium movement (GO:0003352)7.10683787
22cilium movement (GO:0003341)6.72362084
23microtubule depolymerization (GO:0007019)6.47679464
24male meiosis I (GO:0007141)6.43601255
25epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)6.38415525
26single fertilization (GO:0007338)6.28068983
27meiotic nuclear division (GO:0007126)6.02845942
28spermatogenesis (GO:0007283)6.02040687
29male gamete generation (GO:0048232)6.00196308
30chromosome organization involved in meiosis (GO:0070192)5.98111573
31resolution of meiotic recombination intermediates (GO:0000712)5.93901136
32fertilization (GO:0009566)5.69874411
33gamete generation (GO:0007276)5.61268433
34regulation of meiosis I (GO:0060631)5.51213367
35DNA synthesis involved in DNA repair (GO:0000731)5.41016904
36meiosis I (GO:0007127)5.40735199
37negative regulation of inclusion body assembly (GO:0090084)5.33031655
38sperm capacitation (GO:0048240)5.32750978
39germ cell development (GO:0007281)5.28457420
40cellular process involved in reproduction in multicellular organism (GO:0022412)5.07034127
41regulation of posttranscriptional gene silencing (GO:0060147)4.70225578
42regulation of gene silencing by miRNA (GO:0060964)4.70225578
43regulation of gene silencing by RNA (GO:0060966)4.70225578
44monoubiquitinated protein deubiquitination (GO:0035520)4.69390457
45meiotic cell cycle (GO:0051321)4.68907713
46regulation of inclusion body assembly (GO:0090083)4.47158134
47gene silencing by RNA (GO:0031047)4.41474544
48multicellular organismal reproductive process (GO:0048609)4.40144509
49organic cation transport (GO:0015695)4.32656144
50regulation of microtubule-based movement (GO:0060632)4.31946600
51ventricular system development (GO:0021591)4.29608904
52meiotic cell cycle process (GO:1903046)4.24711149
53negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)4.23464725
54chromosome condensation (GO:0030261)4.21778643
55microtubule severing (GO:0051013)4.18380911
56DNA packaging (GO:0006323)4.13411163
57chromatin remodeling at centromere (GO:0031055)4.11482888
58calcium ion-dependent exocytosis (GO:0017156)4.11246477
59seminiferous tubule development (GO:0072520)4.11042109
60cell recognition (GO:0008037)4.00076094
61CENP-A containing nucleosome assembly (GO:0034080)3.89859265
62nuclear pore complex assembly (GO:0051292)3.88203780
63DNA strand renaturation (GO:0000733)3.69442652
64DNA alkylation (GO:0006305)3.62467611
65DNA methylation (GO:0006306)3.62467611
66gonadal mesoderm development (GO:0007506)3.62392312
67regulation of DNA endoreduplication (GO:0032875)3.58636575
68negative regulation of DNA-templated transcription, elongation (GO:0032785)3.57215465
69regulation of spindle checkpoint (GO:0090231)3.55258590
70microtubule polymerization or depolymerization (GO:0031109)3.54582184
71regulation of histone H3-K9 methylation (GO:0051570)3.54509033
72spermatid nucleus differentiation (GO:0007289)3.53819585
73mitotic sister chromatid cohesion (GO:0007064)3.53707895
74chaperone-mediated protein complex assembly (GO:0051131)3.52030417
75mitotic chromosome condensation (GO:0007076)3.50322438
76lung-associated mesenchyme development (GO:0060484)3.46005498
77glycerol ether metabolic process (GO:0006662)3.44065704
78nuclear pore organization (GO:0006999)3.40171764
79gene silencing (GO:0016458)3.38573612
80multicellular organismal development (GO:0007275)3.33831398
81genitalia morphogenesis (GO:0035112)3.32869495
82left/right pattern formation (GO:0060972)3.32750191
83sister chromatid cohesion (GO:0007062)3.25886065
84nucleus organization (GO:0006997)3.22154973
85synapsis (GO:0007129)3.20534615
86ether metabolic process (GO:0018904)3.15710781
87DNA replication checkpoint (GO:0000076)3.12045766
88protein K11-linked deubiquitination (GO:0035871)3.09165548
89glucocorticoid receptor signaling pathway (GO:0042921)3.08387794
90regulation of centriole replication (GO:0046599)3.06962710
91ATP-dependent chromatin remodeling (GO:0043044)3.06557745
92single strand break repair (GO:0000012)3.05290140
93intraciliary transport (GO:0042073)3.04870032
94protein polyglutamylation (GO:0018095)3.04631786
95oogenesis (GO:0048477)3.01637535
96oocyte maturation (GO:0001556)2.99928078
97DNA replication initiation (GO:0006270)2.99331849
98DNA replication-independent nucleosome assembly (GO:0006336)2.96563689
99DNA replication-independent nucleosome organization (GO:0034724)2.96563689
100regulation of meiotic cell cycle (GO:0051445)2.95351378
101rRNA methylation (GO:0031167)2.95194310
102somatic diversification of immune receptors via somatic mutation (GO:0002566)2.92710109
103somatic hypermutation of immunoglobulin genes (GO:0016446)2.92710109
104reciprocal DNA recombination (GO:0035825)2.91160341
105reciprocal meiotic recombination (GO:0007131)2.91160341
106DNA modification (GO:0006304)2.89647021
107pore complex assembly (GO:0046931)2.89593011
108protein localization to chromosome, centromeric region (GO:0071459)2.89575976
109negative regulation of DNA-dependent DNA replication (GO:2000104)2.88585919
110nucleotide transmembrane transport (GO:1901679)2.87372922
111DNA recombination (GO:0006310)2.86966863
112non-recombinational repair (GO:0000726)2.86668083
113double-strand break repair via nonhomologous end joining (GO:0006303)2.86668083
114positive regulation of meiosis (GO:0045836)2.85916686
115mitochondrial DNA replication (GO:0006264)2.85802475
116regulation of nuclear cell cycle DNA replication (GO:0033262)2.85408951
117histone exchange (GO:0043486)2.83574701
118protein localization to cilium (GO:0061512)2.83372530
119centriole replication (GO:0007099)2.81340354
120centriole assembly (GO:0098534)2.80992366
121chromosome organization (GO:0051276)2.80174928
122positive regulation of meiotic cell cycle (GO:0051446)2.79377480
123DNA biosynthetic process (GO:0071897)2.78029270
124membrane repolarization during action potential (GO:0086011)2.77567550
125regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.77402358
126nuclear division (GO:0000280)2.73865736
127DNA-dependent DNA replication (GO:0006261)2.73571427
128spindle assembly (GO:0051225)2.72081518
129DNA methylation or demethylation (GO:0044728)2.71721409
130establishment of protein localization to Golgi (GO:0072600)2.70988944
131heterochromatin organization (GO:0070828)2.70982078
132behavioral response to nicotine (GO:0035095)2.69129078
133protein K6-linked ubiquitination (GO:0085020)2.67570874
134somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.66696629
135isotype switching (GO:0045190)2.66696629
136somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.66696629
137oocyte development (GO:0048599)2.65539244
138DNA replication-dependent nucleosome assembly (GO:0006335)2.64597656
139DNA replication-dependent nucleosome organization (GO:0034723)2.64597656
140protein refolding (GO:0042026)2.63641814
141female gamete generation (GO:0007292)2.63070014
142proteasome assembly (GO:0043248)2.62785750
143microtubule-based movement (GO:0007018)2.60736956
144regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.60637904
145regulation of mitotic spindle checkpoint (GO:1903504)2.60637904
146negative regulation of meiosis (GO:0045835)2.60402219
147membrane repolarization during cardiac muscle cell action potential (GO:0086013)2.58597630
148attachment of spindle microtubules to kinetochore (GO:0008608)2.55971336
149regulation of meiosis (GO:0040020)2.55106230
150regulation of translation, ncRNA-mediated (GO:0045974)2.54490655
151fusion of sperm to egg plasma membrane (GO:0007342)11.8826934
152piRNA metabolic process (GO:0034587)11.1382469
153sperm motility (GO:0030317)10.5078944

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.59678365
2BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.79845376
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.57487416
4EZH2_22144423_ChIP-Seq_EOC_Human3.30287182
5NOTCH1_21737748_ChIP-Seq_TLL_Human2.93025388
6CREM_20920259_ChIP-Seq_GC1-SPG_Mouse2.84112800
7GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.83082943
8STAT6_21828071_ChIP-Seq_BEAS2B_Human2.71278401
9DCP1A_22483619_ChIP-Seq_HELA_Human2.43247699
10IGF1R_20145208_ChIP-Seq_DFB_Human2.41604056
11CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.37963601
12PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.36230915
13FLI1_27457419_Chip-Seq_LIVER_Mouse2.34745372
14KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.27474265
15MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.25203573
16GATA1_26923725_Chip-Seq_HPCs_Mouse2.20266879
17JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.13687143
18FOXM1_23109430_ChIP-Seq_U2OS_Human2.11106729
19VDR_23849224_ChIP-Seq_CD4+_Human2.08171986
20GABP_17652178_ChIP-ChIP_JURKAT_Human2.07859066
21POU5F1_18555785_ChIP-Seq_MESCs_Mouse2.06008259
22MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse10.7060490
23PCGF2_27294783_Chip-Seq_ESCs_Mouse1.94866012
24ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.93329389
25KAP1_22055183_ChIP-Seq_ESCs_Mouse1.91121755
26XRN2_22483619_ChIP-Seq_HELA_Human1.85700850
27E2F1_21310950_ChIP-Seq_MCF-7_Human1.85031101
28TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.84555559
29EWS_26573619_Chip-Seq_HEK293_Human1.82624334
30MYC_18940864_ChIP-ChIP_HL60_Human1.79956093
31GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.76856150
32ZNF274_21170338_ChIP-Seq_K562_Hela1.74342348
33TP63_19390658_ChIP-ChIP_HaCaT_Human1.74178861
34VDR_22108803_ChIP-Seq_LS180_Human1.69562393
35KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.66976461
36ELK4_26923725_Chip-Seq_MESODERM_Mouse1.66799328
37STAT1_17558387_ChIP-Seq_HELA_Human1.66335098
38KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.65579240
39FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.64188645
40FOXP3_21729870_ChIP-Seq_TREG_Human1.62519111
41E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.62391433
42E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.61502118
43PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.60277409
44NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.60221704
45ETS1_20019798_ChIP-Seq_JURKAT_Human1.60046485
46BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.59140938
47WDR5_24793694_ChIP-Seq_LNCAP_Human1.56918663
48TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.55072846
49RBPJ_22232070_ChIP-Seq_NCS_Mouse1.54852626
50EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.54816759
51FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.53044233
52HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.51561973
53EST1_17652178_ChIP-ChIP_JURKAT_Human1.51324300
54TTF2_22483619_ChIP-Seq_HELA_Human1.48215939
55MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.47751942
56RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.47714310
57MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.47440869
58RUNX1_26923725_Chip-Seq_HPCs_Mouse1.45203146
59POU5F1_16153702_ChIP-ChIP_HESCs_Human1.43893491
60ERA_21632823_ChIP-Seq_H3396_Human1.43234803
61GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.42444115
62GATA3_21867929_ChIP-Seq_CD8_Mouse1.39497536
63GATA3_21867929_ChIP-Seq_TH1_Mouse1.39233479
64RNF2_27304074_Chip-Seq_NSC_Mouse1.38877074
65NFE2_27457419_Chip-Seq_LIVER_Mouse1.36998878
66GABP_19822575_ChIP-Seq_HepG2_Human1.34426949
67FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.29015468
68TP53_22573176_ChIP-Seq_HFKS_Human1.28117771
69CBX2_27304074_Chip-Seq_ESCs_Mouse1.27400799
70EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.25958487
71MYC_19829295_ChIP-Seq_ESCs_Human1.25087086
72SOX2_22085726_ChIP-Seq_NPCs_Mouse1.25062505
73IRF1_19129219_ChIP-ChIP_H3396_Human1.23992877
74SUZ12_27294783_Chip-Seq_NPCs_Mouse1.21921064
75MYC_19079543_ChIP-ChIP_MESCs_Mouse1.21643003
76SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.21435959
77CREB1_15753290_ChIP-ChIP_HEK293T_Human1.21165369
78NANOG_20526341_ChIP-Seq_ESCs_Human1.20827434
79PHF8_20622854_ChIP-Seq_HELA_Human1.19453075
80PCGF2_27294783_Chip-Seq_NPCs_Mouse1.19419565
81TAL1_26923725_Chip-Seq_HPCs_Mouse1.19322425
82YY1_21170310_ChIP-Seq_MESCs_Mouse1.19221862
83FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.19130042
84KDM5A_27292631_Chip-Seq_BREAST_Human1.16488916
85SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.16477975
86TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.15340965
87LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.13262799
88RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.12917422
89KDM2B_26808549_Chip-Seq_REH_Human1.12409229
90CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.12023156
91SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.11122445
92MYC_19030024_ChIP-ChIP_MESCs_Mouse1.10529245
93IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.10321626
94CBP_20019798_ChIP-Seq_JUKART_Human1.10321626
95MYC_18555785_ChIP-Seq_MESCs_Mouse1.09864827
96P53_21459846_ChIP-Seq_SAOS-2_Human1.09671060
97CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.09115673
98RUNX2_22187159_ChIP-Seq_PCA_Human1.08245156
99FOXA1_21572438_ChIP-Seq_LNCaP_Human1.07538425
100TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06927100
101POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.06927100
102GF1_26923725_Chip-Seq_HPCs_Mouse1.04496748
103CRX_20693478_ChIP-Seq_RETINA_Mouse1.04424815
104SOX2_16153702_ChIP-ChIP_HESCs_Human1.04361225
105FLI1_21867929_ChIP-Seq_TH2_Mouse1.03770799
106TAF15_26573619_Chip-Seq_HEK293_Human1.03187584
107GATA1_22025678_ChIP-Seq_K562_Human1.02742356
108RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human1.02683588
109EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.00816438
110CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.00777688
111OCT4_20526341_ChIP-Seq_ESCs_Human1.00256202
112SPI1_26923725_Chip-Seq_HPCs_Mouse0.99058019
113NANOG_18555785_Chip-Seq_ESCs_Mouse0.98572559
114THAP11_20581084_ChIP-Seq_MESCs_Mouse0.97656350
115BCAT_22108803_ChIP-Seq_LS180_Human0.97573934
116P68_20966046_ChIP-Seq_HELA_Human0.97364786
117CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.97219296
118MYC_18358816_ChIP-ChIP_MESCs_Mouse0.97145398
119SRF_21415370_ChIP-Seq_HL-1_Mouse0.96536774
120FUS_26573619_Chip-Seq_HEK293_Human0.96435347
121NELFA_20434984_ChIP-Seq_ESCs_Mouse0.95731123
122SALL1_21062744_ChIP-ChIP_HESCs_Human0.95602633
123AUTS2_25519132_ChIP-Seq_293T-REX_Human0.94907824
124LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.94493225
125OCT4_18555785_Chip-Seq_ESCs_Mouse0.94454870
126FLI1_21867929_ChIP-Seq_CD8_Mouse0.94258729
127BCL6_27268052_Chip-Seq_Bcells_Human0.94004005
128EZH2_27294783_Chip-Seq_NPCs_Mouse0.93736388
129RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.93453742
130CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.93310221
131GATA3_21878914_ChIP-Seq_MCF-7_Human0.93051198
132E2F1_18555785_ChIP-Seq_MESCs_Mouse0.92827700
133NFYB_21822215_ChIP-Seq_K562_Human0.92574551
134MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.91795308
135ERG_20517297_ChIP-Seq_VCAP_Human0.91570317
136CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.90983353
137CTBP2_25329375_ChIP-Seq_LNCAP_Human0.90981799
138KLF4_18555785_Chip-Seq_ESCs_Mouse0.90875475
139ZFP57_27257070_Chip-Seq_ESCs_Mouse0.90868176
140PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.90647534
141GATA3_26560356_Chip-Seq_TH1_Human0.90302460
142STAT3_18555785_ChIP-Seq_MESCs_Mouse0.90098599
143HOXB7_26014856_ChIP-Seq_BT474_Human0.90046253
144OCT4_21477851_ChIP-Seq_ESCs_Mouse0.89723972
145DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.89602756
146ETV1_20927104_ChIP-Seq_GIST48_Human0.89474105
147NCOR_22424771_ChIP-Seq_293T_Human0.89225978
148REST_21632747_ChIP-Seq_MESCs_Mouse0.87839117
149ESRRB_18555785_Chip-Seq_ESCs_Mouse0.87806881
150MYCN_18555785_ChIP-Seq_MESCs_Mouse0.86798491
151SOX2_21211035_ChIP-Seq_LN229_Human0.86281791
152POU3F2_20337985_ChIP-ChIP_501MEL_Human0.85721491
153RXRA_24833708_ChIP-Seq_LIVER_Mouse0.85565451
154EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.85340426
155TBL1_22424771_ChIP-Seq_293T_Human0.85185378
156FOXH1_21741376_ChIP-Seq_EPCs_Human0.85153898
157FOXP1_21924763_ChIP-Seq_HESCs_Human0.85031333
158SOX9_26525672_Chip-Seq_HEART_Mouse0.84394627
159VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.83819264
160UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.83570818
161ESET_19884257_ChIP-Seq_ESCs_Mouse0.83540549
162TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.82897620
163E2F4_17652178_ChIP-ChIP_JURKAT_Human0.82693082
164YY1_22570637_ChIP-Seq_MALME-3M_Human0.82686239
165AR_21909140_ChIP-Seq_LNCAP_Human0.82358631
166EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.82304912
167BCOR_27268052_Chip-Seq_Bcells_Human0.82175863
168EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.81283335
169PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.81075592
170OCT4_19829295_ChIP-Seq_ESCs_Human0.81013137
171GF1B_26923725_Chip-Seq_HPCs_Mouse0.80910481
172ELK1_19687146_ChIP-ChIP_HELA_Human0.80315864
173P53_22387025_ChIP-Seq_ESCs_Mouse0.80117628
174RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.79964617

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008877_abnormal_DNA_methylation7.19506541
2MP0001929_abnormal_gametogenesis5.62083727
3MP0003698_abnormal_male_reproductive5.60331465
4MP0003136_yellow_coat_color4.33387504
5MP0002210_abnormal_sex_determination4.30702355
6MP0001145_abnormal_male_reproductive3.58239708
7MP0002161_abnormal_fertility/fecundity3.25898421
8MP0000653_abnormal_sex_gland3.25237188
9MP0005174_abnormal_tail_pigmentation3.24486030
10MP0000013_abnormal_adipose_tissue3.17831647
11MP0003011_delayed_dark_adaptation2.67796011
12MP0002653_abnormal_ependyma_morphology2.56509529
13MP0008995_early_reproductive_senescence2.55420705
14MP0010094_abnormal_chromosome_stability2.17386597
15MP0005171_absent_coat_pigmentation2.06941821
16MP0008058_abnormal_DNA_repair2.05843450
17MP0002160_abnormal_reproductive_system2.04571164
18MP0005410_abnormal_fertilization12.4610302
19MP0003111_abnormal_nucleus_morphology1.90659240
20MP0001485_abnormal_pinna_reflex1.87103688
21MP0005670_abnormal_white_adipose1.79749696
22MP0005423_abnormal_somatic_nervous1.71874928
23MP0005623_abnormal_meninges_morphology1.68028546
24MP0003786_premature_aging1.67771268
25MP0001188_hyperpigmentation1.65010361
26MP0003646_muscle_fatigue1.59872704
27MP0000003_abnormal_adipose_tissue1.57427515
28MP0010030_abnormal_orbit_morphology1.56965524
29MP0002102_abnormal_ear_morphology1.56842057
30MP0008057_abnormal_DNA_replication1.48952877
31MP0003693_abnormal_embryo_hatching1.47732393
32MP0004215_abnormal_myocardial_fiber1.44989136
33MP0000015_abnormal_ear_pigmentation1.40092111
34MP0005409_darkened_coat_color1.38245643
35MP0003077_abnormal_cell_cycle1.35106383
36MP0005377_hearing/vestibular/ear_phenot1.34054965
37MP0003878_abnormal_ear_physiology1.34054965
38MP0003195_calcinosis1.33361706
39MP0003718_maternal_effect1.31098221
40MP0000383_abnormal_hair_follicle1.28231921
41MP0004233_abnormal_muscle_weight1.27527506
42MP0004957_abnormal_blastocyst_morpholog1.23905823
43MP0005083_abnormal_biliary_tract1.20229700
44MP0005167_abnormal_blood-brain_barrier1.19124035
45MP0002009_preneoplasia1.16891193
46MP0003763_abnormal_thymus_physiology1.15666806
47MP0003699_abnormal_female_reproductive1.15479419
48MP0003123_paternal_imprinting1.15236473
49MP0005647_abnormal_sex_gland1.14898280
50MP0001730_embryonic_growth_arrest1.13920631
51MP0005389_reproductive_system_phenotype1.13823495
52MP0008007_abnormal_cellular_replicative1.11732657
53MP0005084_abnormal_gallbladder_morpholo1.10561429
54MP0001119_abnormal_female_reproductive1.07559148
55MP0002638_abnormal_pupillary_reflex1.00749718
56MP0005253_abnormal_eye_physiology0.98651676
57MP0002938_white_spotting0.94043033
58MP0002282_abnormal_trachea_morphology0.92689568
59MP0001324_abnormal_eye_pigmentation0.89224067
60MP0003787_abnormal_imprinting0.88038508
61MP0010307_abnormal_tumor_latency0.84503663
62MP0000647_abnormal_sebaceous_gland0.83054540
63MP0003115_abnormal_respiratory_system0.82434733
64MP0008932_abnormal_embryonic_tissue0.79954031
65MP0002084_abnormal_developmental_patter0.70315995
66MP0004145_abnormal_muscle_electrophysio0.69994522
67MP0005645_abnormal_hypothalamus_physiol0.69957992
68MP0002254_reproductive_system_inflammat0.69945651
69MP0005380_embryogenesis_phenotype0.69513832
70MP0001672_abnormal_embryogenesis/_devel0.69513832
71MP0001697_abnormal_embryo_size0.67955820
72MP0003121_genomic_imprinting0.66961169
73MP0002085_abnormal_embryonic_tissue0.66650145
74MP0003567_abnormal_fetal_cardiomyocyte0.65871156
75MP0004019_abnormal_vitamin_homeostasis0.65813138
76MP0000566_synostosis0.65014045
77MP0000490_abnormal_crypts_of0.64953036
78MP0005551_abnormal_eye_electrophysiolog0.64507823
79MP0001486_abnormal_startle_reflex0.63201730
80MP0004808_abnormal_hematopoietic_stem0.62281510
81MP0010678_abnormal_skin_adnexa0.61526816
82MP0001293_anophthalmia0.60587573
83MP0006292_abnormal_olfactory_placode0.59398210
84MP0000350_abnormal_cell_proliferation0.59392724
85MP0002095_abnormal_skin_pigmentation0.59377510
86MP0001765_abnormal_ion_homeostasis0.59131986
87MP0003137_abnormal_impulse_conducting0.58632765
88MP0003183_abnormal_peptide_metabolism0.57467731
89MP0001727_abnormal_embryo_implantation0.56327583
90MP0009672_abnormal_birth_weight0.56093699
91MP0009046_muscle_twitch0.55733766
92MP0003315_abnormal_perineum_morphology0.55511843
93MP0002234_abnormal_pharynx_morphology0.55457162
94MP0001661_extended_life_span0.55448731
95MP0005395_other_phenotype0.55219088
96MP0001984_abnormal_olfaction0.54458430
97MP0003984_embryonic_growth_retardation0.53660324
98MP0005451_abnormal_body_composition0.53370880
99MP0000313_abnormal_cell_death0.52371185
100MP0003861_abnormal_nervous_system0.52284119
101MP0005666_abnormal_adipose_tissue0.50936615
102MP0002080_prenatal_lethality0.50903300
103MP0003943_abnormal_hepatobiliary_system0.49744901
104MP0003936_abnormal_reproductive_system0.49348981
105MP0002088_abnormal_embryonic_growth/wei0.48839661
106MP0004381_abnormal_hair_follicle0.46813240
107MP0008875_abnormal_xenobiotic_pharmacok0.46158297
108MP0001986_abnormal_taste_sensitivity0.45857566
109MP0000026_abnormal_inner_ear0.45856134
110MP0003890_abnormal_embryonic-extraembry0.45575030
111MP0006035_abnormal_mitochondrial_morpho0.45344882
112MP0002751_abnormal_autonomic_nervous0.44599276
113MP0005397_hematopoietic_system_phenotyp0.44096565
114MP0001545_abnormal_hematopoietic_system0.44096565
115MP0000358_abnormal_cell_content/0.43228354
116MP0001529_abnormal_vocalization0.40162093
117MP0004197_abnormal_fetal_growth/weight/0.40130890
118MP0009278_abnormal_bone_marrow0.39428322
119MP0003937_abnormal_limbs/digits/tail_de0.38121308
120MP0002269_muscular_atrophy0.37787881
121MP0003879_abnormal_hair_cell0.37290037
122MP0000569_abnormal_digit_pigmentation0.36136928
123MP0009703_decreased_birth_body0.34885124
124MP0002971_abnormal_brown_adipose0.33229712
125MP0002086_abnormal_extraembryonic_tissu0.32932760
126MP0003329_amyloid_beta_deposits0.32505989
127MP0004742_abnormal_vestibular_system0.32118082
128MP0003942_abnormal_urinary_system0.31469683
129MP0006072_abnormal_retinal_apoptosis0.31026883
130MP0000432_abnormal_head_morphology0.30777371
131MP0000534_abnormal_ureter_morphology0.29872641
132MP0009115_abnormal_fat_cell0.29574839
133MP0001440_abnormal_grooming_behavior0.28436726
134MP0002092_abnormal_eye_morphology0.28416672
135MP0005391_vision/eye_phenotype0.27978617
136MP0002152_abnormal_brain_morphology0.27726805
137MP0000427_abnormal_hair_cycle0.27526741
138MP0005076_abnormal_cell_differentiation0.27451091
139MP0001919_abnormal_reproductive_system0.27393454
140MP0002019_abnormal_tumor_incidence0.27320284
141MP0004036_abnormal_muscle_relaxation0.26883075
142MP0000462_abnormal_digestive_system0.26744639
143MP0005187_abnormal_penis_morphology0.25140353
144MP0001915_intracranial_hemorrhage0.24057310
145MP0003119_abnormal_digestive_system0.23797542

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)8.50976266
2Abnormal respiratory epithelium morphology (HP:0012253)8.30746311
3Abnormal respiratory motile cilium morphology (HP:0005938)8.30746311
4Rhinitis (HP:0012384)7.15873920
5Infertility (HP:0000789)6.78866598
6Chronic bronchitis (HP:0004469)6.68804709
7Abnormal ciliary motility (HP:0012262)6.66206380
8Male infertility (HP:0003251)5.76612344
9Nasal polyposis (HP:0100582)5.44215557
10Abnormal spermatogenesis (HP:0008669)4.93733284
11Birth length less than 3rd percentile (HP:0003561)4.39081982
12Abnormality of the nasal mucosa (HP:0000433)4.34397637
13Testicular atrophy (HP:0000029)4.34072500
14Azoospermia (HP:0000027)4.26237599
15Bronchiectasis (HP:0002110)4.23838075
16Nephronophthisis (HP:0000090)4.06092522
17Bronchitis (HP:0012387)4.05465817
18Rectal fistula (HP:0100590)3.96849865
19Rectovaginal fistula (HP:0000143)3.96849865
20Impulsivity (HP:0100710)3.79593150
21Intestinal fistula (HP:0100819)3.73820911
22Abnormality of DNA repair (HP:0003254)3.39421611
23Gonadotropin excess (HP:0000837)3.35217089
24Absent radius (HP:0003974)3.34842898
25Vaginal fistula (HP:0004320)3.30635495
26Poikiloderma (HP:0001029)3.28861279
27Duplicated collecting system (HP:0000081)3.25530488
28Attenuation of retinal blood vessels (HP:0007843)3.19008550
29Aplasia involving forearm bones (HP:0009822)3.12749546
30Absent forearm bone (HP:0003953)3.12749546
31Sensory axonal neuropathy (HP:0003390)3.06258392
32Abnormality of the renal medulla (HP:0100957)3.04442480
33Patellar aplasia (HP:0006443)3.03211086
34Abnormality of the renal collecting system (HP:0004742)2.99868805
35Recurrent otitis media (HP:0000403)2.97843799
36Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.87380180
37Degeneration of the lateral corticospinal tracts (HP:0002314)2.87380180
38Recurrent sinusitis (HP:0011108)2.87322163
39Congenital stationary night blindness (HP:0007642)2.85350717
40Menstrual irregularities (HP:0000858)2.81360451
41Rib fusion (HP:0000902)2.79095058
42Aplasia/Hypoplasia of the patella (HP:0006498)2.77777227
43Bony spicule pigmentary retinopathy (HP:0007737)2.77239178
44Tubulointerstitial nephritis (HP:0001970)2.74412048
45Volvulus (HP:0002580)2.63937135
46Abnormality of the lower motor neuron (HP:0002366)2.61963538
47Medial flaring of the eyebrow (HP:0010747)2.57644880
48Molar tooth sign on MRI (HP:0002419)2.56240174
49Abnormality of midbrain morphology (HP:0002418)2.56240174
50Premature ovarian failure (HP:0008209)2.47375943
51Progressive external ophthalmoplegia (HP:0000590)2.46262498
52Absent thumb (HP:0009777)2.42235932
53Tubular atrophy (HP:0000092)2.35048577
54Recurrent bronchitis (HP:0002837)2.29906556
55Abnormality of the duodenum (HP:0002246)2.29784109
56Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.28842181
57Clubbing of toes (HP:0100760)2.27929434
58Abnormality of the corticospinal tract (HP:0002492)2.27839484
59Rimmed vacuoles (HP:0003805)2.27250241
60Microvesicular hepatic steatosis (HP:0001414)2.24349274
61Annular pancreas (HP:0001734)2.23691615
62Abnormality of the labia majora (HP:0012881)2.22796693
63Scotoma (HP:0000575)2.21640463
64Shoulder girdle muscle weakness (HP:0003547)2.20642946
65Duplication of thumb phalanx (HP:0009942)2.20386494
66Hypoplasia of the capital femoral epiphysis (HP:0003090)2.20283471
67Short chin (HP:0000331)2.19375746
68Abnormal biliary tract physiology (HP:0012439)2.18368286
69Bile duct proliferation (HP:0001408)2.18368286
70Abnormality of the labia minora (HP:0012880)2.17803909
71Hypergonadotropic hypogonadism (HP:0000815)2.17044393
72Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.15480459
73Heterotopia (HP:0002282)2.14491431
74Supernumerary spleens (HP:0009799)2.11658203
75Capillary hemangiomas (HP:0005306)2.11103288
76External ophthalmoplegia (HP:0000544)2.10411078
77Tubulointerstitial abnormality (HP:0001969)2.09696515
78Colon cancer (HP:0003003)2.07433579
79Breast hypoplasia (HP:0003187)2.06176568
80Anteriorly placed anus (HP:0001545)2.02420447
81Amyotrophic lateral sclerosis (HP:0007354)2.02007528
82Respiratory insufficiency due to defective ciliary clearance (HP:0200073)12.2739634
83Absent/shortened dynein arms (HP:0200106)11.8347728
84Dynein arm defect of respiratory motile cilia (HP:0012255)11.8347728
85Absent septum pellucidum (HP:0001331)1.98556278
86Agnosia (HP:0010524)1.98431084
87Progressive muscle weakness (HP:0003323)1.98105889
88Short thumb (HP:0009778)1.96438530
89Short humerus (HP:0005792)1.95085710
90Abnormality of pyrimidine metabolism (HP:0004353)1.93524933
91Aplasia/hypoplasia of the humerus (HP:0006507)1.92803866
92Genetic anticipation (HP:0003743)1.91545415
93Rhabdomyosarcoma (HP:0002859)1.90576318
94Depressed nasal tip (HP:0000437)1.89998618
95Stage 5 chronic kidney disease (HP:0003774)1.89028293
96Malnutrition (HP:0004395)1.87622012
97Hypoplastic labia majora (HP:0000059)1.86807560
98Abnormal lung lobation (HP:0002101)1.84933646
99Spastic tetraparesis (HP:0001285)1.84468110
100Septo-optic dysplasia (HP:0100842)1.81427865
101Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.81370788
102Abnormality of alanine metabolism (HP:0010916)1.81370788
103Hyperalaninemia (HP:0003348)1.81370788
104Ependymoma (HP:0002888)1.78887252
105Microglossia (HP:0000171)1.75762358
106Triphalangeal thumb (HP:0001199)1.75643440
107Congenital primary aphakia (HP:0007707)1.75261392
108Colitis (HP:0002583)1.74661285
109Non-midline cleft lip (HP:0100335)1.74443455
110Horizontal nystagmus (HP:0000666)1.73667953
111Facial cleft (HP:0002006)1.73405907
112Basal cell carcinoma (HP:0002671)1.73229879
113Gait imbalance (HP:0002141)1.73172032
114Impaired vibratory sensation (HP:0002495)1.73171515
115Postaxial foot polydactyly (HP:0001830)1.71158956
116Abnormality of the septum pellucidum (HP:0007375)1.71099256
117Chronic hepatic failure (HP:0100626)1.70392535
118Poor coordination (HP:0002370)1.70168890
119Hypoalbuminemia (HP:0003073)1.69743698
120Abnormal albumin level (HP:0012116)1.69743698
121Abnormality of the carotid arteries (HP:0005344)1.68035166
122Metabolic alkalosis (HP:0200114)1.67307168
123Papillary thyroid carcinoma (HP:0002895)1.67142427
124Absent epiphyses (HP:0010577)1.67048617
125Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.67048617
126Impaired vibration sensation in the lower limbs (HP:0002166)1.65815147
127Neoplasm of striated muscle (HP:0009728)1.64567356
128Short ribs (HP:0000773)1.59306869
129Pancreatic fibrosis (HP:0100732)1.59075963
130Fibular hypoplasia (HP:0003038)1.57416999
131Ectopic kidney (HP:0000086)1.52489706
132Facial hemangioma (HP:0000329)1.52101710
133Oculomotor apraxia (HP:0000657)1.49888594
134Cholecystitis (HP:0001082)1.46631604
135Abnormal gallbladder physiology (HP:0012438)1.46631604
136Chromsome breakage (HP:0040012)1.46565666
137Aplasia/Hypoplasia of the lens (HP:0008063)1.46121235
138Truncal obesity (HP:0001956)1.45574219
139Tubulointerstitial fibrosis (HP:0005576)1.45522510
140Nephrogenic diabetes insipidus (HP:0009806)1.44966219
141Short nail (HP:0001799)1.43346868
142Genital tract atresia (HP:0001827)1.42578417
143Postaxial hand polydactyly (HP:0001162)1.41642623
144Aplasia/Hypoplasia of the uvula (HP:0010293)1.40263260
145Vaginal atresia (HP:0000148)1.40234097
146Difficulty climbing stairs (HP:0003551)1.40157030
147Chromosomal breakage induced by crosslinking agents (HP:0003221)1.40106642
148Sloping forehead (HP:0000340)1.40057013
149Male pseudohermaphroditism (HP:0000037)1.39690888
150Abnormality of ocular smooth pursuit (HP:0000617)1.39022202
151Abnormality of the renal cortex (HP:0011035)1.37842725
152Congenital hepatic fibrosis (HP:0002612)1.37555963
153Renal dysplasia (HP:0000110)1.36453815
154Bundle branch block (HP:0011710)1.36333935
155Broad distal phalanx of finger (HP:0009836)1.35586513
156Abnormality of the phalanges of the hallux (HP:0010057)1.34993533
157Abnormality of chromosome stability (HP:0003220)1.31231261
158Degeneration of anterior horn cells (HP:0002398)1.30736022
159Abnormality of the anterior horn cell (HP:0006802)1.30736022
160Abnormality of permanent molar morphology (HP:0011071)1.29960708
161Abnormality of the dental root (HP:0006486)1.29960708
162Taurodontia (HP:0000679)1.29960708
163Meckel diverticulum (HP:0002245)1.27712364
164Nephroblastoma (Wilms tumor) (HP:0002667)1.27173744
165Aplasia/Hypoplasia of the tongue (HP:0010295)1.25464291
16611 pairs of ribs (HP:0000878)1.23815103
167Dyschromatopsia (HP:0007641)1.23455874
168Abnormality of the preputium (HP:0100587)1.22501986
169Upper motor neuron abnormality (HP:0002127)1.21528676
170Tongue fasciculations (HP:0001308)1.20319124
171Congenital malformation of the right heart (HP:0011723)1.19353741
172Double outlet right ventricle (HP:0001719)1.19353741
173Cleft eyelid (HP:0000625)1.19039366
174Abnormality of the ileum (HP:0001549)1.18791703
175Abnormality of molar morphology (HP:0011070)1.18694487
176Abnormality of molar (HP:0011077)1.18694487
177Oligodactyly (hands) (HP:0001180)1.17500817
178Small intestinal stenosis (HP:0012848)1.17155868
179Duodenal stenosis (HP:0100867)1.17155868
180Primary amenorrhea (HP:0000786)1.17027965
181Easy fatigability (HP:0003388)1.16998346

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK47.12446583
2PDK37.12446583
3PRKD35.36930910
4TESK14.87099784
5PDK24.47014132
6ICK3.69318633
7ZAK2.68974329
8NEK22.53288732
9PNCK2.51473822
10BMPR1B2.15266302
11PTK2B2.11656008
12ACVR1B2.08279022
13TAOK32.07250739
14CDC72.06192343
15CDK122.03299634
16PBK1.92815999
17CSF1R1.88217270
18CDK191.86224188
19WNK41.80869085
20STK391.75605522
21TAF11.70509922
22PLK41.69199484
23TTK1.66139435
24STK381.65118603
25WEE11.46116417
26FRK1.39041575
27OXSR11.37162960
28TLK11.35596207
29TGFBR11.34732673
30TYRO31.34394461
31STK31.28691367
32STK161.27852968
33MST41.27702278
34CHEK21.23489984
35DYRK31.15519406
36MKNK11.14593821
37STK38L1.13205222
38ADRBK21.06957558
39PLK11.05537767
40BUB11.01997094
41DYRK1B0.99737652
42CHEK10.97804282
43LATS20.93220334
44EIF2AK30.92678214
45MAP3K40.89497620
46MAPK110.87404649
47NUAK10.86495953
48EEF2K0.85114330
49CAMK1G0.81316706
50LATS10.79606622
51FGFR10.76020367
52ATM0.74537924
53PDK10.74116224
54WNK10.73267862
55STK240.71722742
56BRSK20.71491887
57TXK0.70818871
58ATR0.66956318
59CCNB10.66689632
60TSSK60.66362866
61MAP3K60.63284874
62RPS6KA50.62949483
63TRIM280.60783096
64CDK40.54862966
65PIK3CG0.53118726
66CLK10.52133866
67INSRR0.51770445
68GRK10.51132345
69PASK0.50845343
70PAK10.50760759
71WNK30.50461047
72TESK20.49941668
73MTOR0.49609214
74TIE10.47786397
75BMX0.47557220
76VRK10.47508935
77PLK30.46651512
78FGFR20.46100401
79BRSK10.46021821
80MAP3K90.45775460
81BRAF0.42824610
82LMTK20.42699266
83TAOK10.40631223
84IRAK10.40613197
85MUSK0.40328044
86MST1R0.39893858
87PHKG10.39277213
88PHKG20.39277213
89AURKA0.38866329
90ADRBK10.38484304
91RPS6KA60.37922213
92PAK60.37716508
93PRKAA10.37396925
94AURKB0.37385634
95NEK60.37296179
96CDK70.37225079
97MAPK150.37002113
98NTRK20.36757206
99PDPK10.36155009
100CDK20.35931267
101IGF1R0.35746986
102CDK10.34669865
103PINK10.34273548
104PAK20.31074940
105CAMK10.30335827
106IRAK20.29797894
107PTK60.29627368
108MELK0.29494022
109VRK20.28562132
110MAP2K20.27822015
111MARK30.27200861
112BRD40.26958214
113MAP2K60.26210147
114RIPK40.25327659
115CDK90.22418932
116MAP3K100.21519543
117PRKCI0.20704208
118GSK3B0.20367487
119MAP2K70.19913261
120CSNK1D0.19761884
121MAPKAPK50.19583503
122PAK40.16907020
123STK110.16744182
124EIF2AK10.16351126
125MARK20.16274466
126RIPK10.15253349
127SRPK10.14717076
128CSNK2A20.14450919
129CSNK2A10.14159179
130MAP2K40.13919838
131CSNK1E0.13660671
132PRKDC0.13206939
133MAP3K50.12763879
134MKNK20.12281803
135PRKCG0.12006226
136RPS6KB10.11501660
137CDK30.10212963
138PDGFRB0.09030385
139MAPK100.08944211
140DYRK20.08868638
141PLK20.08803062
142CAMK1D0.07047313
143MAPK80.06768498
144ERBB40.06674772
145DYRK1A0.06585338
146RPS6KA10.06331497

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007504.88667561
2Basal transcription factors_Homo sapiens_hsa030224.48742450
3Sulfur relay system_Homo sapiens_hsa041223.11924719
4Fatty acid biosynthesis_Homo sapiens_hsa000613.10223266
5Fanconi anemia pathway_Homo sapiens_hsa034602.98462334
6Linoleic acid metabolism_Homo sapiens_hsa005912.87265764
7alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.86263009
8RNA transport_Homo sapiens_hsa030132.80513960
9Glycolysis / Gluconeogenesis_Homo sapiens_hsa000102.76875453
10Oocyte meiosis_Homo sapiens_hsa041142.75804867
11Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.70085182
12Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.51321940
13Dorso-ventral axis formation_Homo sapiens_hsa043202.50436854
14Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.44856349
15Nitrogen metabolism_Homo sapiens_hsa009102.40286135
16mRNA surveillance pathway_Homo sapiens_hsa030152.35981872
17Pyruvate metabolism_Homo sapiens_hsa006202.24520836
18Cell cycle_Homo sapiens_hsa041102.12554355
19Glucagon signaling pathway_Homo sapiens_hsa049222.00338582
20Glycerophospholipid metabolism_Homo sapiens_hsa005641.92189440
21Pentose phosphate pathway_Homo sapiens_hsa000301.87140533
22Selenocompound metabolism_Homo sapiens_hsa004501.86489898
23Homologous recombination_Homo sapiens_hsa034401.86174165
24Glycerolipid metabolism_Homo sapiens_hsa005611.69347524
25Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.68400731
26Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.63421370
27Propanoate metabolism_Homo sapiens_hsa006401.57630900
28Ether lipid metabolism_Homo sapiens_hsa005651.55581431
29Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.54827664
30RNA degradation_Homo sapiens_hsa030181.46457917
31Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.45341687
32Purine metabolism_Homo sapiens_hsa002301.40942166
33Lysine degradation_Homo sapiens_hsa003101.37746132
34Cysteine and methionine metabolism_Homo sapiens_hsa002701.36122958
35Carbohydrate digestion and absorption_Homo sapiens_hsa049731.35465621
36ABC transporters_Homo sapiens_hsa020101.30298899
37Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.24907873
38Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.24625311
39Amphetamine addiction_Homo sapiens_hsa050311.19384426
40Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.18080184
41Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.16159917
42Glycosaminoglycan degradation_Homo sapiens_hsa005311.16057891
43Huntingtons disease_Homo sapiens_hsa050161.13853291
44DNA replication_Homo sapiens_hsa030301.13241143
45Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.12860385
46Non-homologous end-joining_Homo sapiens_hsa034501.11868361
47One carbon pool by folate_Homo sapiens_hsa006701.11500677
48Mineral absorption_Homo sapiens_hsa049781.11237156
49Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.08461366
50Pyrimidine metabolism_Homo sapiens_hsa002401.06173663
51Fatty acid degradation_Homo sapiens_hsa000711.05776242
52Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.02781938
53Spliceosome_Homo sapiens_hsa030401.02399060
54RNA polymerase_Homo sapiens_hsa030201.01494013
55Hedgehog signaling pathway_Homo sapiens_hsa043400.98715853
56Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.92652811
57Nucleotide excision repair_Homo sapiens_hsa034200.91837486
58Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.90828416
59Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.90600891
60p53 signaling pathway_Homo sapiens_hsa041150.87649204
61Nicotine addiction_Homo sapiens_hsa050330.86077766
62Fat digestion and absorption_Homo sapiens_hsa049750.86028813
63PPAR signaling pathway_Homo sapiens_hsa033200.85276335
64Butanoate metabolism_Homo sapiens_hsa006500.83319343
65Antigen processing and presentation_Homo sapiens_hsa046120.82817269
66Hippo signaling pathway_Homo sapiens_hsa043900.81345607
67Tryptophan metabolism_Homo sapiens_hsa003800.81068764
68Regulation of autophagy_Homo sapiens_hsa041400.80552720
69Phototransduction_Homo sapiens_hsa047440.77989780
70Biosynthesis of amino acids_Homo sapiens_hsa012300.74897289
71Retinol metabolism_Homo sapiens_hsa008300.74396046
72Base excision repair_Homo sapiens_hsa034100.73835094
73beta-Alanine metabolism_Homo sapiens_hsa004100.73833390
74Long-term potentiation_Homo sapiens_hsa047200.73302829
75Estrogen signaling pathway_Homo sapiens_hsa049150.70191459
76Olfactory transduction_Homo sapiens_hsa047400.68391364
77Carbon metabolism_Homo sapiens_hsa012000.66649378
78Thyroid hormone signaling pathway_Homo sapiens_hsa049190.66443994
79Epstein-Barr virus infection_Homo sapiens_hsa051690.65422185
80Arachidonic acid metabolism_Homo sapiens_hsa005900.65039042
81Fructose and mannose metabolism_Homo sapiens_hsa000510.61384166
82Folate biosynthesis_Homo sapiens_hsa007900.60875421
83Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.60486946
84Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.58740461
85Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.57738471
86Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.57651292
87Renin secretion_Homo sapiens_hsa049240.56206762
88Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.56135026
89Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.54806170
90Proteasome_Homo sapiens_hsa030500.54090779
91Mismatch repair_Homo sapiens_hsa034300.53561338
92Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.53190722
93Inositol phosphate metabolism_Homo sapiens_hsa005620.52933076
94VEGF signaling pathway_Homo sapiens_hsa043700.52538712
95Fatty acid elongation_Homo sapiens_hsa000620.51184006
96Glutathione metabolism_Homo sapiens_hsa004800.50526311
97cGMP-PKG signaling pathway_Homo sapiens_hsa040220.49589809
98Phosphatidylinositol signaling system_Homo sapiens_hsa040700.48994446
99Primary immunodeficiency_Homo sapiens_hsa053400.48640482
100Ovarian steroidogenesis_Homo sapiens_hsa049130.48385563
101Cardiac muscle contraction_Homo sapiens_hsa042600.47205470
102Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.46040371
103Maturity onset diabetes of the young_Homo sapiens_hsa049500.42476634
104Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.40328944
105Fatty acid metabolism_Homo sapiens_hsa012120.40037852
106AMPK signaling pathway_Homo sapiens_hsa041520.39301083
107Caffeine metabolism_Homo sapiens_hsa002320.37573915
108Central carbon metabolism in cancer_Homo sapiens_hsa052300.37374083
109Viral carcinogenesis_Homo sapiens_hsa052030.35425170
110Vitamin digestion and absorption_Homo sapiens_hsa049770.33222327
111Adipocytokine signaling pathway_Homo sapiens_hsa049200.33038392
112Vascular smooth muscle contraction_Homo sapiens_hsa042700.32185197
113Herpes simplex infection_Homo sapiens_hsa051680.31816177
114Collecting duct acid secretion_Homo sapiens_hsa049660.30875604
115Peroxisome_Homo sapiens_hsa041460.29768182
116Wnt signaling pathway_Homo sapiens_hsa043100.28988376
117cAMP signaling pathway_Homo sapiens_hsa040240.27716058
118Circadian rhythm_Homo sapiens_hsa047100.27516948
119Chemical carcinogenesis_Homo sapiens_hsa052040.26639567
120Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.26364372
121NF-kappa B signaling pathway_Homo sapiens_hsa040640.26156485
122Calcium signaling pathway_Homo sapiens_hsa040200.26084275
123Tight junction_Homo sapiens_hsa045300.25160123
124Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.23602227
125Systemic lupus erythematosus_Homo sapiens_hsa053220.23404019
126Adherens junction_Homo sapiens_hsa045200.23075954
127Longevity regulating pathway - mammal_Homo sapiens_hsa042110.22595873
128Metabolic pathways_Homo sapiens_hsa011000.22482524
129Endocytosis_Homo sapiens_hsa041440.22400296
130HTLV-I infection_Homo sapiens_hsa051660.21855070
131Renin-angiotensin system_Homo sapiens_hsa046140.21511865
132Thyroid hormone synthesis_Homo sapiens_hsa049180.21140177
133Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.18838692
134Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.18250954
135Prostate cancer_Homo sapiens_hsa052150.17835472
136Cocaine addiction_Homo sapiens_hsa050300.16613878
137Colorectal cancer_Homo sapiens_hsa052100.15771905
138Steroid biosynthesis_Homo sapiens_hsa001000.15314006
139Intestinal immune network for IgA production_Homo sapiens_hsa046720.15221548
140Influenza A_Homo sapiens_hsa051640.14428815
141Sphingolipid metabolism_Homo sapiens_hsa006000.14300401
142Drug metabolism - other enzymes_Homo sapiens_hsa009830.13827548
143Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.13768246
144Basal cell carcinoma_Homo sapiens_hsa052170.13415419
145TGF-beta signaling pathway_Homo sapiens_hsa043500.13211170
146Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.12462140
147Protein digestion and absorption_Homo sapiens_hsa049740.12459074
148Taste transduction_Homo sapiens_hsa047420.12252934

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