NXPH3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1daunorubicin metabolic process (GO:0044597)8.06401719
2polyketide metabolic process (GO:0030638)8.06401719
3doxorubicin metabolic process (GO:0044598)8.06401719
4synaptic vesicle maturation (GO:0016188)6.38594312
5proline transport (GO:0015824)6.13221690
6cellular potassium ion homeostasis (GO:0030007)6.06190511
7sodium ion export (GO:0071436)5.83644957
8membrane depolarization during cardiac muscle cell action potential (GO:0086012)5.52697427
9regulation of mammary gland epithelial cell proliferation (GO:0033599)5.36634673
10cerebellar granule cell differentiation (GO:0021707)5.31522244
11maintenance of protein location in nucleus (GO:0051457)5.27074843
12regulation of response to osmotic stress (GO:0047484)5.25107860
13aminoglycoside antibiotic metabolic process (GO:0030647)5.21642330
14regulation of synaptic vesicle transport (GO:1902803)5.12773135
15somite rostral/caudal axis specification (GO:0032525)5.08850954
16negative regulation of epidermis development (GO:0045683)4.77417034
17regulation of neuronal synaptic plasticity (GO:0048168)4.70567854
18postsynaptic membrane organization (GO:0001941)4.56406465
19cell communication by electrical coupling involved in cardiac conduction (GO:0086064)4.55476680
20regulation of cilium movement (GO:0003352)4.55390989
21histone H4-K5 acetylation (GO:0043981)4.50525131
22histone H4-K8 acetylation (GO:0043982)4.50525131
23ionotropic glutamate receptor signaling pathway (GO:0035235)4.46622056
24neuronal action potential propagation (GO:0019227)4.45079374
25muscle organ morphogenesis (GO:0048644)4.41847616
26L-amino acid import (GO:0043092)4.33446615
27regulation of long-term neuronal synaptic plasticity (GO:0048169)4.32891901
28neurotransmitter-gated ion channel clustering (GO:0072578)4.32488207
29negative regulation of G2/M transition of mitotic cell cycle (GO:0010972)4.32278925
30glutamate secretion (GO:0014047)4.31719367
31regulation of synapse maturation (GO:0090128)4.29092315
32regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)4.25159877
33potassium ion import (GO:0010107)4.21750694
34response to dietary excess (GO:0002021)4.16849766
35negative regulation of telomerase activity (GO:0051974)4.12895160
36potassium ion homeostasis (GO:0055075)4.12582250
37phenol-containing compound catabolic process (GO:0019336)4.12267489
38neurotransmitter transport (GO:0006836)4.09865421
39histone H4-K12 acetylation (GO:0043983)4.09541242
40amino acid import (GO:0043090)4.06376027
41neuromuscular process controlling balance (GO:0050885)4.05162192
42regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.02388728
43auditory behavior (GO:0031223)4.02115530
44negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147)3.99373268
45cell communication by electrical coupling (GO:0010644)3.97896515
46regulation of MHC class I biosynthetic process (GO:0045343)3.97721680
47microtubule severing (GO:0051013)3.95430996
48positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.92999516
49negative regulation of synaptic transmission, GABAergic (GO:0032229)3.89056714
50regulation of ARF protein signal transduction (GO:0032012)3.82278322
51regulation of short-term neuronal synaptic plasticity (GO:0048172)3.80727740
52negative regulation of cell cycle G2/M phase transition (GO:1902750)3.78923461
53calcium-mediated signaling using intracellular calcium source (GO:0035584)3.78810219
54protein polyglutamylation (GO:0018095)3.77775457
55axon ensheathment in central nervous system (GO:0032291)3.77725500
56central nervous system myelination (GO:0022010)3.77725500
57neuron cell-cell adhesion (GO:0007158)3.77634863
58positive regulation of membrane potential (GO:0045838)3.75927965
59regulation of neurotransmitter levels (GO:0001505)3.74558941
60regulation of excitatory postsynaptic membrane potential (GO:0060079)3.74481572
61hormone catabolic process (GO:0042447)3.73385231
62neuronal ion channel clustering (GO:0045161)3.72234068
63synaptic transmission, glutamatergic (GO:0035249)3.67262322
64negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.66969380
65detection of temperature stimulus (GO:0016048)3.66383075
66dendritic spine morphogenesis (GO:0060997)3.65817744
67locomotory exploration behavior (GO:0035641)3.65066738
68cellular sodium ion homeostasis (GO:0006883)3.64406415
69mitochondrion distribution (GO:0048311)3.64054649
70regulation of synaptic plasticity (GO:0048167)3.62742717
71regulation of telomere maintenance via telomerase (GO:0032210)3.62042703
72long-term memory (GO:0007616)3.57585122
73synaptic vesicle endocytosis (GO:0048488)3.57337510
74ventricular system development (GO:0021591)3.57128907
75positive regulation of dendritic spine development (GO:0060999)3.56632449
76regulation of neurotransmitter secretion (GO:0046928)3.56406114
77rRNA transcription (GO:0009303)3.50424433
78glutamate receptor signaling pathway (GO:0007215)3.50006204
79layer formation in cerebral cortex (GO:0021819)3.49426606
80gamma-aminobutyric acid transport (GO:0015812)3.48707692
81regulation of microtubule-based movement (GO:0060632)3.47882049
82synaptic vesicle docking involved in exocytosis (GO:0016081)3.46969331
83histone H4-K16 acetylation (GO:0043984)3.46537263
84notochord development (GO:0030903)3.45260058
85tachykinin receptor signaling pathway (GO:0007217)3.44843624
86regulation of postsynaptic membrane potential (GO:0060078)3.44313883
87cytoskeletal anchoring at plasma membrane (GO:0007016)3.44125846
88regulation of vesicle fusion (GO:0031338)3.43981837
89cytidine catabolic process (GO:0006216)3.41965400
90cytidine deamination (GO:0009972)3.41965400
91cytidine metabolic process (GO:0046087)3.41965400
92negative regulation of epidermal cell differentiation (GO:0045605)3.41078447
93regulation of voltage-gated calcium channel activity (GO:1901385)3.37093048
94regulation of nuclear cell cycle DNA replication (GO:0033262)3.34464106
95cerebellar Purkinje cell differentiation (GO:0021702)3.33171762
96synaptic vesicle exocytosis (GO:0016079)3.30429529
97positive regulation of neurotransmitter secretion (GO:0001956)3.29353893
98neuromuscular process controlling posture (GO:0050884)3.26770654
99positive regulation of neurotransmitter transport (GO:0051590)3.26600685
100neuron-neuron synaptic transmission (GO:0007270)3.25692197
101positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.24479157
102protein localization to kinetochore (GO:0034501)3.24323878
103regulation of neurotransmitter transport (GO:0051588)3.23844293
104positive regulation of muscle cell apoptotic process (GO:0010661)3.23571624
105heterochromatin organization (GO:0070828)3.22271191
106cerebral cortex neuron differentiation (GO:0021895)3.22199846
107membrane depolarization during action potential (GO:0086010)3.22152491
108gamma-aminobutyric acid signaling pathway (GO:0007214)3.21270883
109response to auditory stimulus (GO:0010996)3.20510520
110cardiovascular system development (GO:0072358)3.17828167
111cerebellar Purkinje cell layer development (GO:0021680)3.16541520
112membrane depolarization (GO:0051899)3.15066905
113positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.14439787
114arachidonic acid secretion (GO:0050482)3.11435492
115icosanoid secretion (GO:0032309)3.11435492
116positive regulation of axon extension (GO:0045773)3.10604727
117branching involved in mammary gland duct morphogenesis (GO:0060444)3.09953941
118vocalization behavior (GO:0071625)3.05626095
119mechanosensory behavior (GO:0007638)3.04937309
120regulation of dendritic spine morphogenesis (GO:0061001)3.04615182
121activation of protein kinase A activity (GO:0034199)3.04596978
122cell differentiation in hindbrain (GO:0021533)3.04572276
123glomerular visceral epithelial cell development (GO:0072015)3.03534633
124neuromuscular process (GO:0050905)3.02121175
125cell communication involved in cardiac conduction (GO:0086065)3.01537559
126negative regulation of peptidyl-serine phosphorylation (GO:0033137)3.01235910
127regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)3.01029301
128neurotransmitter uptake (GO:0001504)3.00206232
129negative regulation of potassium ion transmembrane transport (GO:1901380)2.99820973
130primitive streak formation (GO:0090009)2.99566621
131coenzyme catabolic process (GO:0009109)2.98560896
132maintenance of protein localization in organelle (GO:0072595)2.96634122
133regulation of synaptic transmission (GO:0050804)2.96133163
134regulation of synaptic vesicle exocytosis (GO:2000300)2.96110740
135regulation of apoptotic process involved in morphogenesis (GO:1902337)2.95257617
136positive regulation of synapse maturation (GO:0090129)2.94644708
137protein localization to cilium (GO:0061512)2.94007529
138regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.93987507
139regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.93399172
140protein localization to synapse (GO:0035418)2.93204052
141regulation of dendritic spine development (GO:0060998)2.92985911
142phosphatidylinositol 3-kinase signaling (GO:0014065)2.90954915
143nucleoside transmembrane transport (GO:1901642)2.89903602
144negative regulation of dendrite morphogenesis (GO:0050774)2.89866450
145acidic amino acid transport (GO:0015800)2.89789288
146positive regulation of dendrite development (GO:1900006)2.89543490
147sensory perception of smell (GO:0007608)2.89188435
148cell fate commitment involved in formation of primary germ layer (GO:0060795)2.89072690
149pre-miRNA processing (GO:0031054)2.88817559
150intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (GO:0070059)2.88779076
151presynaptic membrane organization (GO:0097090)2.85595862
152positive regulation of dendritic spine morphogenesis (GO:0061003)2.83440660
153regulation of odontogenesis of dentin-containing tooth (GO:0042487)2.83115728
154cellular modified amino acid catabolic process (GO:0042219)2.82849690
155long-term synaptic potentiation (GO:0060291)2.81654255
156exploration behavior (GO:0035640)2.80715147
157hypotonic response (GO:0006971)2.80204514
158mating behavior (GO:0007617)2.79022283
159regulation of synaptic transmission, glutamatergic (GO:0051966)2.78739416
160dendritic spine organization (GO:0097061)2.78070185
161chemosensory behavior (GO:0007635)2.77726192
162presynaptic membrane assembly (GO:0097105)2.75347983
163signal release (GO:0023061)2.75203287
164epoxygenase P450 pathway (GO:0019373)2.74999077
165glomerular epithelial cell development (GO:0072310)2.74919308
166quinone metabolic process (GO:1901661)2.74254867
167interferon-gamma production (GO:0032609)2.74187364
168transepithelial transport (GO:0070633)2.73499949
169cell migration in hindbrain (GO:0021535)2.72902031
170neurotransmitter secretion (GO:0007269)2.72542641
171mitochondrion localization (GO:0051646)2.72504777
172positive regulation of protein deacetylation (GO:0090312)2.70135904
173regulation of intracellular estrogen receptor signaling pathway (GO:0033146)2.69827910
174positive regulation of histone deacetylation (GO:0031065)2.69812342
175ovulation cycle (GO:0042698)2.69370752
176cell migration involved in gastrulation (GO:0042074)2.68482809
177positive regulation of macrophage cytokine production (GO:0060907)2.67985899
178pyrimidine ribonucleoside catabolic process (GO:0046133)2.67950709
179mitotic sister chromatid segregation (GO:0000070)2.64805503
180regulation of glutamate receptor signaling pathway (GO:1900449)2.64702933
181regulation of synapse structural plasticity (GO:0051823)2.64420568

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human5.23925447
2KLF2_18264089_ChIP-ChIP_MESCs_Mouse4.96985954
3KLF5_18264089_ChIP-ChIP_MESCs_Mouse4.96985954
4KLF4_18264089_ChIP-ChIP_MESCs_Mouse4.96985954
5SMAD3_22036565_ChIP-Seq_ESCs_Mouse3.08126697
6* NACC1_18358816_ChIP-ChIP_MESCs_Mouse2.80809541
7EZH2_22144423_ChIP-Seq_EOC_Human2.59546016
8* SOX2_18358816_ChIP-ChIP_MESCs_Mouse2.46614497
9EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.42748565
10* ZFP281_18757296_ChIP-ChIP_E14_Mouse2.30146058
11NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.22867333
12IKZF1_21737484_ChIP-ChIP_HCT116_Human2.21942622
13* ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.10497684
14EZH2_18974828_ChIP-Seq_MESCs_Mouse2.04899479
15RNF2_18974828_ChIP-Seq_MESCs_Mouse2.04899479
16POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.02380475
17TP63_19390658_ChIP-ChIP_HaCaT_Human1.97345820
18* ZFP281_27345836_Chip-Seq_ESCs_Mouse1.96872582
19* TCF3_18692474_ChIP-Seq_MESCs_Mouse1.95948373
20ERG_21242973_ChIP-ChIP_JURKAT_Human1.95169946
21* NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.91255027
22* KDM2B_26808549_Chip-Seq_K562_Human1.87058819
23* RARB_27405468_Chip-Seq_BRAIN_Mouse1.85534649
24NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.83466800
25SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.83103466
26MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.83002644
27* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.76816375
28TCF3_18692474_ChIP-Seq_MEFs_Mouse1.71168266
29* REST_21632747_ChIP-Seq_MESCs_Mouse1.70539236
30* SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.69748379
31TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.66947115
32* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.65326984
33* SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.63448151
34* RING1B_27294783_Chip-Seq_NPCs_Mouse1.63112986
35* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.60811816
36JARID2_20064375_ChIP-Seq_MESCs_Mouse1.60046221
37REST_18959480_ChIP-ChIP_MESCs_Mouse1.59969965
38CDX2_20551321_ChIP-Seq_CACO-2_Human1.59474636
39* TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.58872576
40RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.58194481
41RNF2_27304074_Chip-Seq_ESCs_Mouse1.57209331
42PRDM14_21183938_ChIP-Seq_MESCs_Mouse1.56334491
43ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.56062588
44SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.55760299
45POU5F1_16518401_ChIP-PET_MESCs_Mouse1.49946782
46SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.49597359
47ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.47463623
48PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.47307855
49* NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.45520152
50GBX2_23144817_ChIP-Seq_PC3_Human1.45486694
51* JARID2_20075857_ChIP-Seq_MESCs_Mouse1.45314966
52GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.43751317
53TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.43148902
54NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.40733258
55MTF2_20144788_ChIP-Seq_MESCs_Mouse1.38671293
56RNF2_27304074_Chip-Seq_NSC_Mouse1.38665172
57* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.37639333
58EZH2_27304074_Chip-Seq_ESCs_Mouse1.37082132
59TRIM28_21343339_ChIP-Seq_HEK293_Human1.36437343
60SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.35395772
61E2F1_17053090_ChIP-ChIP_MCF-7_Human1.35357407
62CTCF_27219007_Chip-Seq_Bcells_Human1.35158683
63SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.34509244
64SMC4_20622854_ChIP-Seq_HELA_Human1.34143994
65KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.33036948
66* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.32584774
67TP53_20018659_ChIP-ChIP_R1E_Mouse1.30288874
68PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.29977908
69EZH2_27294783_Chip-Seq_ESCs_Mouse1.27184384
70EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.23157156
71STAT6_21828071_ChIP-Seq_BEAS2B_Human1.21032769
72TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.20376262
73* ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.19180857
74* RING1B_27294783_Chip-Seq_ESCs_Mouse1.18642242
75* LXR_22292898_ChIP-Seq_THP-1_Human1.18545255
76OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.17456382
77NANOG_18692474_ChIP-Seq_MESCs_Mouse1.17401145
78NANOG_16518401_ChIP-PET_MESCs_Mouse1.17276616
79* TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.15410314
80ESR2_21235772_ChIP-Seq_MCF-7_Human1.15310355
81HIF1A_21447827_ChIP-Seq_MCF-7_Human1.12642532
82* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.12446085
83* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.12114830
84DNAJC2_21179169_ChIP-ChIP_NT2_Human1.11618342
85TBX3_20139965_ChIP-Seq_ESCs_Mouse1.11406320
86NR3C1_23031785_ChIP-Seq_PC12_Mouse1.11287921
87RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.10914690
88TBX3_20139965_ChIP-Seq_MESCs_Mouse1.10236706
89GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.09196907
90POU5F1_18692474_ChIP-Seq_MESCs_Mouse1.08514456
91SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.08034133
92RARG_19884340_ChIP-ChIP_MEFs_Mouse1.07610936
93SMAD3_21741376_ChIP-Seq_HESCs_Human1.02516223
94RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.01248693
95KDM2B_26808549_Chip-Seq_DND41_Human1.01073823
96PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.01033178
97* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.00967744
98ESR1_21235772_ChIP-Seq_MCF-7_Human1.00772224
99* POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.00526119
100DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.00431921
101* AR_19668381_ChIP-Seq_PC3_Human1.00255320
102AR_21572438_ChIP-Seq_LNCaP_Human1.00202397
103TP53_23651856_ChIP-Seq_MEFs_Mouse0.99303094
104* ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.97072966
105TET1_21490601_ChIP-Seq_MESCs_Mouse0.96814678
106CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.96616001
107TP53_22127205_ChIP-Seq_IMR90_Human0.96103770
108OCT4_19829295_ChIP-Seq_ESCs_Human0.95397650
109CTNNB1_20460455_ChIP-Seq_HCT116_Human0.94199289
110DROSHA_22980978_ChIP-Seq_HELA_Human0.93428000
111SETDB1_19884255_ChIP-Seq_MESCs_Mouse0.92149730
112SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.92132092
113IRF1_19129219_ChIP-ChIP_H3396_Human0.91882387
114CREB1_26743006_Chip-Seq_LNCaP_Human0.91283944
115NANOG_18692474_ChIP-Seq_MEFs_Mouse0.91164038
116EED_16625203_ChIP-ChIP_MESCs_Mouse0.90442137
117NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.90080512
118THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.89837620
119TCF7_22412390_ChIP-Seq_EML_Mouse0.89434838
120ELK4_26923725_Chip-Seq_MESODERM_Mouse0.89210851
121* SOX2_18692474_ChIP-Seq_MESCs_Mouse0.88984885
122CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.88486378
123UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.88299198
124BMI1_23680149_ChIP-Seq_NPCS_Mouse0.88219861
125SOX3_22085726_ChIP-Seq_NPCs_Mouse0.88059506
126KLF4_19829295_ChIP-Seq_ESCs_Human0.87981143
127YAP1_20516196_ChIP-Seq_MESCs_Mouse0.87567767
128* DPY_21335234_ChIP-Seq_ESCs_Mouse0.87168990
129PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.86128491
130P68_20966046_ChIP-Seq_HELA_Human0.83820083
131KDM2B_26808549_Chip-Seq_JURKAT_Human0.82120774
132SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.81593190
133SRY_22984422_ChIP-ChIP_TESTIS_Rat0.80921896
134* MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.80480671
135CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.79469200
136ZNF217_24962896_ChIP-Seq_MCF-7_Human0.76806088
137SMAD4_21741376_ChIP-Seq_ESCs_Human0.76242241
138BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.74617243
139EP300_21415370_ChIP-Seq_HL-1_Mouse0.74137188
140VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.74061717
141RUNX1_26923725_Chip-Seq_HPCs_Mouse0.73539828
142SOX2_21211035_ChIP-Seq_LN229_Gbm0.72872893
143* GATA1_26923725_Chip-Seq_HPCs_Mouse0.71811721
144TET1_21451524_ChIP-Seq_MESCs_Mouse0.71626283
145CDX2_19796622_ChIP-Seq_MESCs_Mouse0.70647138
146* MYC_27129775_Chip-Seq_CORNEA_Mouse0.70406540

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004858_abnormal_nervous_system4.43393743
2MP0005394_taste/olfaction_phenotype4.16225740
3MP0005499_abnormal_olfactory_system4.16225740
4MP0004859_abnormal_synaptic_plasticity4.05915715
5MP0006292_abnormal_olfactory_placode3.33684589
6MP0002254_reproductive_system_inflammat3.09471599
7MP0003122_maternal_imprinting3.03777152
8MP0003011_delayed_dark_adaptation2.99454294
9MP0004264_abnormal_extraembryonic_tissu2.87574703
10MP0003890_abnormal_embryonic-extraembry2.79136564
11MP0003329_amyloid_beta_deposits2.75696748
12MP0004270_analgesia2.72449329
13MP0008569_lethality_at_weaning2.57617199
14MP0003879_abnormal_hair_cell2.43018356
15MP0002735_abnormal_chemical_nociception2.35923336
16MP0003635_abnormal_synaptic_transmissio2.35448165
17MP0002653_abnormal_ependyma_morphology2.26113546
18MP0008961_abnormal_basal_metabolism2.14659007
19MP0001984_abnormal_olfaction2.13945154
20MP0003690_abnormal_glial_cell2.06153175
21MP0002332_abnormal_exercise_endurance2.00216849
22* MP0002063_abnormal_learning/memory/cond1.94592705
23MP0008789_abnormal_olfactory_epithelium1.92996169
24MP0009780_abnormal_chondrocyte_physiolo1.92172989
25MP0005623_abnormal_meninges_morphology1.86870397
26MP0002572_abnormal_emotion/affect_behav1.85150728
27MP0002736_abnormal_nociception_after1.82568247
28MP0000920_abnormal_myelination1.82057722
29MP0003121_genomic_imprinting1.80397817
30MP0009046_muscle_twitch1.78294298
31MP0005075_abnormal_melanosome_morpholog1.77200282
32MP0002734_abnormal_mechanical_nocicepti1.76158812
33MP0003938_abnormal_ear_development1.75814350
34MP0000678_abnormal_parathyroid_gland1.75517562
35MP0003705_abnormal_hypodermis_morpholog1.75355755
36MP0003283_abnormal_digestive_organ1.71428835
37MP0001502_abnormal_circadian_rhythm1.70156965
38MP0005257_abnormal_intraocular_pressure1.69110582
39MP0006035_abnormal_mitochondrial_morpho1.65246348
40MP0002064_seizures1.64444687
41MP0002909_abnormal_adrenal_gland1.62260156
42MP0003633_abnormal_nervous_system1.61430134
43MP0002184_abnormal_innervation1.60287709
44MP0000778_abnormal_nervous_system1.54925596
45MP0003183_abnormal_peptide_metabolism1.54405858
46MP0005646_abnormal_pituitary_gland1.52149628
47MP0001348_abnormal_lacrimal_gland1.49657037
48MP0000955_abnormal_spinal_cord1.49090747
49MP0009745_abnormal_behavioral_response1.48021371
50MP0003880_abnormal_central_pattern1.47522542
51MP0003787_abnormal_imprinting1.43729619
52MP0003631_nervous_system_phenotype1.39786735
53MP0002733_abnormal_thermal_nociception1.39430480
54MP0010030_abnormal_orbit_morphology1.36843161
55MP0002233_abnormal_nose_morphology1.36021630
56* MP0001486_abnormal_startle_reflex1.34288640
57MP0004924_abnormal_behavior1.33333899
58MP0005386_behavior/neurological_phenoty1.33333899
59MP0000604_amyloidosis1.31334668
60MP0001177_atelectasis1.30264382
61MP0004043_abnormal_pH_regulation1.29075058
62MP0001986_abnormal_taste_sensitivity1.26358255
63MP0010352_gastrointestinal_tract_polyps1.26223153
64MP0001849_ear_inflammation1.25632891
65MP0003137_abnormal_impulse_conducting1.23551229
66MP0004811_abnormal_neuron_physiology1.23248054
67MP0002932_abnormal_joint_morphology1.22802948
68MP0005167_abnormal_blood-brain_barrier1.22390677
69MP0003123_paternal_imprinting1.17713419
70MP0002272_abnormal_nervous_system1.16094991
71MP0001970_abnormal_pain_threshold1.12870591
72MP0005423_abnormal_somatic_nervous1.12706193
73MP0000751_myopathy1.12604317
74MP0003119_abnormal_digestive_system1.12120005
75MP0003632_abnormal_nervous_system1.11274666
76MP0002127_abnormal_cardiovascular_syste1.10637659
77MP0002882_abnormal_neuron_morphology1.08454727
78MP0000049_abnormal_middle_ear1.07978375
79MP0004742_abnormal_vestibular_system1.06822695
80MP0000762_abnormal_tongue_morphology1.05808305
81MP0001440_abnormal_grooming_behavior1.05446643
82MP0001293_anophthalmia1.04350746
83MP0003861_abnormal_nervous_system1.02093340
84MP0001501_abnormal_sleep_pattern1.01904601
85MP0004130_abnormal_muscle_cell0.99575643
86MP0006276_abnormal_autonomic_nervous0.99165138
87MP0003075_altered_response_to0.98091567
88MP0005248_abnormal_Harderian_gland0.98088951
89MP0002752_abnormal_somatic_nervous0.97918797
90MP0008770_decreased_survivor_rate0.97822668
91MP0002114_abnormal_axial_skeleton0.96313671
92MP0002557_abnormal_social/conspecific_i0.95241846
93MP0001958_emphysema0.92948043
94MP0003755_abnormal_palate_morphology0.92603402
95MP0002092_abnormal_eye_morphology0.92224036
96MP0001968_abnormal_touch/_nociception0.89492853
97MP0001963_abnormal_hearing_physiology0.88481519
98MP0005380_embryogenesis_phenotype0.87804819
99MP0001672_abnormal_embryogenesis/_devel0.87804819
100MP0008872_abnormal_physiological_respon0.87558363
101MP0002751_abnormal_autonomic_nervous0.87310989
102MP0008874_decreased_physiological_sensi0.87040491
103MP0002152_abnormal_brain_morphology0.86832997
104MP0002081_perinatal_lethality0.85757186
105MP0004147_increased_porphyrin_level0.84922091
106MP0002229_neurodegeneration0.84825665
107MP0003935_abnormal_craniofacial_develop0.84224983
108MP0005409_darkened_coat_color0.82891120
109MP0005535_abnormal_body_temperature0.81422283
110MP0004085_abnormal_heartbeat0.80903721
111MP0002088_abnormal_embryonic_growth/wei0.80878848
112MP0003942_abnormal_urinary_system0.80841153
113MP0004885_abnormal_endolymph0.80670019
114MP0004133_heterotaxia0.80142437
115MP0001905_abnormal_dopamine_level0.79659975
116MP0000428_abnormal_craniofacial_morphol0.79049205
117MP0000534_abnormal_ureter_morphology0.78901862
118MP0002067_abnormal_sensory_capabilities0.78773129
119MP0004145_abnormal_muscle_electrophysio0.78497004
120MP0003984_embryonic_growth_retardation0.78413339
121MP0002116_abnormal_craniofacial_bone0.76934619
122MP0005503_abnormal_tendon_morphology0.76875686
123MP0002277_abnormal_respiratory_mucosa0.76362466
124MP0006082_CNS_inflammation0.74018264
125MP0000579_abnormal_nail_morphology0.72535794
126MP0000631_abnormal_neuroendocrine_gland0.72115832
127MP0001346_abnormal_lacrimal_gland0.72115796
128* MP0002066_abnormal_motor_capabilities/c0.71900608
129MP0004142_abnormal_muscle_tone0.70882571
130MP0001299_abnormal_eye_distance/0.70704469
131MP0002822_catalepsy0.70443699
132MP0002089_abnormal_postnatal_growth/wei0.69954270
133MP0002085_abnormal_embryonic_tissue0.68385545
134MP0002970_abnormal_white_adipose0.67431544
135MP0002069_abnormal_eating/drinking_beha0.66776984
136MP0002638_abnormal_pupillary_reflex0.66079871
137MP0003634_abnormal_glial_cell0.65683177
138MP0004510_myositis0.63700156
139MP0002249_abnormal_larynx_morphology0.63538038
140MP0002084_abnormal_developmental_patter0.62914679
141MP0000747_muscle_weakness0.61406597
142MP0004957_abnormal_blastocyst_morpholog0.61244770
143MP0005266_abnormal_metabolism0.61221933
144MP0003279_aneurysm0.60574381
145MP0010386_abnormal_urinary_bladder0.59116823
146MP0005551_abnormal_eye_electrophysiolog0.58246479
147MP0000566_synostosis0.57973527
148MP0001485_abnormal_pinna_reflex0.57274682
149MP0002295_abnormal_pulmonary_circulatio0.55715498
150MP0010769_abnormal_survival0.53630521
151MP0003172_abnormal_lysosome_physiology0.50754762
152MP0003045_fibrosis0.49818005
153MP0005187_abnormal_penis_morphology0.49441044
154MP0010768_mortality/aging0.49324326
155MP0005388_respiratory_system_phenotype0.49174561
156MP0002133_abnormal_respiratory_system0.49174561
157MP0002090_abnormal_vision0.48346527
158MP0010770_preweaning_lethality0.47789883

Predicted human phenotypes

RankGene SetZ-score
1Bilateral microphthalmos (HP:0007633)6.45172352
2Abnormality of the lower motor neuron (HP:0002366)5.91182820
3Hepatoblastoma (HP:0002884)5.77713800
4Abnormality of binocular vision (HP:0011514)4.90441526
5Diplopia (HP:0000651)4.90441526
6Hypochromic microcytic anemia (HP:0004840)4.89910561
7Supranuclear gaze palsy (HP:0000605)4.73867257
8Neurofibrillary tangles (HP:0002185)4.70825107
9Action tremor (HP:0002345)4.65611555
10Obstructive sleep apnea (HP:0002870)4.34208965
11Annular pancreas (HP:0001734)4.12854240
12Rib fusion (HP:0000902)3.88766736
13Amyotrophic lateral sclerosis (HP:0007354)3.88698119
14Ankle clonus (HP:0011448)3.87421269
15Multiple enchondromatosis (HP:0005701)3.77689823
16Ependymoma (HP:0002888)3.74945444
17Cerebral inclusion bodies (HP:0100314)3.67870660
18Mutism (HP:0002300)3.55261802
19Torticollis (HP:0000473)3.50041007
20Abnormal eating behavior (HP:0100738)3.49467894
21Hyperventilation (HP:0002883)3.40347223
22Progressive cerebellar ataxia (HP:0002073)3.39794560
23Truncal ataxia (HP:0002078)3.33508733
24Astrocytoma (HP:0009592)3.27315013
25Abnormality of the astrocytes (HP:0100707)3.27315013
26Spastic gait (HP:0002064)3.27283542
27Bifid tongue (HP:0010297)3.23785646
28Hemiplegia (HP:0002301)3.17390397
29Absence seizures (HP:0002121)3.16798113
30Limb dystonia (HP:0002451)3.10335966
31Postural instability (HP:0002172)3.07722578
32Febrile seizures (HP:0002373)3.05957077
33Amblyopia (HP:0000646)3.05543281
34Horizontal nystagmus (HP:0000666)3.04439378
35Neoplasm of striated muscle (HP:0009728)2.98482088
36Dysmetria (HP:0001310)2.95143233
37Epileptic encephalopathy (HP:0200134)2.94675469
38Generalized hypotonia (HP:0001290)2.91176703
39Akinesia (HP:0002304)2.88508993
40Nephroblastoma (Wilms tumor) (HP:0002667)2.85213241
41Cerebral hypomyelination (HP:0006808)2.85041264
42Myokymia (HP:0002411)2.82687532
43Focal dystonia (HP:0004373)2.82368972
44Papilledema (HP:0001085)2.80405192
45Focal seizures (HP:0007359)2.79577076
46Urinary bladder sphincter dysfunction (HP:0002839)2.78493730
47Renal duplication (HP:0000075)2.77035682
48Neoplasm of the heart (HP:0100544)2.76891773
49Insomnia (HP:0100785)2.74761822
50Decreased number of large peripheral myelinated nerve fibers (HP:0003387)2.70230746
51Anomalous pulmonary venous return (HP:0010772)2.69117338
52Intention tremor (HP:0002080)2.69029096
53Craniofacial dystonia (HP:0012179)2.68959538
54Depression (HP:0000716)2.66920765
55Neuronal loss in central nervous system (HP:0002529)2.66260053
56Abnormality of the corticospinal tract (HP:0002492)2.64027621
57Embryonal renal neoplasm (HP:0011794)2.64017084
58Testicular atrophy (HP:0000029)2.56542023
59Partial duplication of thumb phalanx (HP:0009944)2.52668326
60Rhabdomyosarcoma (HP:0002859)2.52266521
61Anxiety (HP:0000739)2.51023608
62Hemiparesis (HP:0001269)2.50627299
63Sleep apnea (HP:0010535)2.49928470
64Rectal fistula (HP:0100590)2.49866944
65Rectovaginal fistula (HP:0000143)2.49866944
66Poor eye contact (HP:0000817)2.48524562
67Hand muscle atrophy (HP:0009130)2.47604663
68Tetraplegia (HP:0002445)2.46345251
69Atonic seizures (HP:0010819)2.45882147
70Aplasia/Hypoplasia of the fovea (HP:0008060)2.40926163
71Hypoplasia of the fovea (HP:0007750)2.40926163
72Abnormality of the phalanges of the hallux (HP:0010057)2.39736580
73Abnormality of the salivary glands (HP:0010286)2.38232292
74Bradykinesia (HP:0002067)2.37966433
75Stereotypic behavior (HP:0000733)2.36924716
76Peripheral hypomyelination (HP:0007182)2.36117744
77Ventricular fibrillation (HP:0001663)2.35072086
78Impaired smooth pursuit (HP:0007772)2.35051826
79Resting tremor (HP:0002322)2.34940491
80Fused cervical vertebrae (HP:0002949)2.32933590
81Visual hallucinations (HP:0002367)2.31889112
82Rigidity (HP:0002063)2.29154760
83Ragged-red muscle fibers (HP:0003200)2.28224105
84Sensory axonal neuropathy (HP:0003390)2.27724369
85Abnormality of the pulmonary veins (HP:0011718)2.27611541
86Bundle branch block (HP:0011710)2.27446321
87Abnormality of the pubic bones (HP:0003172)2.27248082
88Shawl scrotum (HP:0000049)2.25655816
89Dialeptic seizures (HP:0011146)2.24600660
90Glioma (HP:0009733)2.24235452
91Difficulty running (HP:0009046)2.23668703
92Large earlobe (HP:0009748)2.22647796
93Turricephaly (HP:0000262)2.20688798
94Partial duplication of the phalanx of hand (HP:0009999)2.19514369
95Intestinal fistula (HP:0100819)2.19236964
96Bronchomalacia (HP:0002780)2.18552203
97Lower limb muscle weakness (HP:0007340)2.18225069
98Dysdiadochokinesis (HP:0002075)2.18084667
99Clonus (HP:0002169)2.17614463
100Achilles tendon contracture (HP:0001771)2.17566951
101Vaginal fistula (HP:0004320)2.16700017
102Shallow orbits (HP:0000586)2.16304581
103Scanning speech (HP:0002168)2.15929142
104Diminished motivation (HP:0000745)2.14799765
105Upper limb amyotrophy (HP:0009129)2.14537667
106Distal upper limb amyotrophy (HP:0007149)2.14537667
107Preauricular skin tag (HP:0000384)2.14223685
108Abnormality of chromosome segregation (HP:0002916)2.14111633
109Cerebral aneurysm (HP:0004944)2.13668790
110Dysmetric saccades (HP:0000641)2.13665106
111Short humerus (HP:0005792)2.12299466
112Heart block (HP:0012722)2.11568590
113Preauricular pit (HP:0004467)2.10793186
114Periauricular skin pits (HP:0100277)2.10793186
115Hyperinsulinemic hypoglycemia (HP:0000825)2.10253882
116Impaired social interactions (HP:0000735)2.09436024
117Abnormal social behavior (HP:0012433)2.09436024
118Abnormality of ocular smooth pursuit (HP:0000617)2.08972879
119Malignant neoplasm of the central nervous system (HP:0100836)2.08636392
120Aplasia involving bones of the extremities (HP:0009825)2.07738259
121Aplasia involving bones of the upper limbs (HP:0009823)2.07738259
122Aplasia of the phalanges of the hand (HP:0009802)2.07738259
123Aplasia/Hypoplasia of the sternum (HP:0006714)2.07525605
124Aplasia/hypoplasia of the humerus (HP:0006507)2.04121590
125Spinal canal stenosis (HP:0003416)2.03624444
126Epileptiform EEG discharges (HP:0011182)2.03355667
127Abnormal atrioventricular conduction (HP:0005150)2.02423725
128Urinary urgency (HP:0000012)2.02334085
129Spastic tetraparesis (HP:0001285)2.01857627
130Hypopigmentation of the fundus (HP:0007894)2.01262642
131Abnormal lung lobation (HP:0002101)2.01108637
132Atrophy/Degeneration involving motor neurons (HP:0007373)2.00325967
133Delusions (HP:0000746)1.99756382
134Abnormality of the musculature of the hand (HP:0001421)1.97338898
135Hyperacusis (HP:0010780)1.96853482
136Lower limb amyotrophy (HP:0007210)1.96030927
137Broad metatarsal (HP:0001783)1.95288097
138Lower limb asymmetry (HP:0100559)1.93429194
139Abnormality of the fovea (HP:0000493)1.93070537
140Pointed chin (HP:0000307)1.92316642
141Skin tags (HP:0010609)1.91903966
142Choreoathetosis (HP:0001266)1.91827620
143Abnormality of the Achilles tendon (HP:0005109)1.91279300
144Apathy (HP:0000741)1.91244225
145Abnormal cartilage morphology (HP:0002763)1.90011212
146Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.89932786
147Generalized tonic-clonic seizures (HP:0002069)1.89483920
148Open mouth (HP:0000194)1.89215985
149Concave nail (HP:0001598)1.88489400
150Nervous tissue neoplasm (HP:0030060)1.87016437
151Neuroectodermal neoplasm (HP:0030061)1.87016437
152Neuroepithelial neoplasm (HP:0030063)1.87016437
153Trismus (HP:0000211)1.86898610
154Impaired vibration sensation in the lower limbs (HP:0002166)1.86247973
155Genetic anticipation (HP:0003743)1.85739696
156Embryonal neoplasm (HP:0002898)1.85389429
157Supernumerary nipples (HP:0002558)1.85065855
158Prolonged QT interval (HP:0001657)1.84642951
159Focal motor seizures (HP:0011153)1.84184210
160Rapidly progressive (HP:0003678)1.84147498
161Drooling (HP:0002307)1.83524685
162Excessive salivation (HP:0003781)1.83524685
163Abnormality of the distal phalanx of the thumb (HP:0009617)1.81519513
164Atrioventricular block (HP:0001678)1.81419076
165Lymphangioma (HP:0100764)1.80061829
166Broad-based gait (HP:0002136)1.79134672
167Angiofibromas (HP:0010615)1.78665306
168Adenoma sebaceum (HP:0009720)1.78665306
169Status epilepticus (HP:0002133)1.77505781
170EEG with generalized epileptiform discharges (HP:0011198)1.77402025
171Dysphonia (HP:0001618)1.76993307
172Pseudobulbar signs (HP:0002200)1.76585161
173Pendular nystagmus (HP:0012043)1.75875988
174Abnormality of the motor neurons (HP:0002450)1.75392267
175Gaze-evoked nystagmus (HP:0000640)1.74926712
176Polyphagia (HP:0002591)1.67899359
177Abnormality of the periventricular white matter (HP:0002518)1.67376275
178Abnormal EKG (HP:0003115)1.66680014
179Slow progression (HP:0003677)1.66277396
180Increased circulating renin level (HP:0000848)1.65831273

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK125.92610558
2GRK55.58497885
3GRK63.75056069
4TYRO33.04839810
5ERN12.99065922
6ADRBK22.73411225
7GRK12.67939346
8MAP3K92.67460572
9MARK12.59552018
10NTRK12.40069251
11CASK2.17062848
12MAP2K41.93527883
13NTRK31.90592668
14MAPK71.83151970
15CSF1R1.81973188
16TGFBR21.76916073
17MATK1.72557990
18MARK21.69764941
19WNK11.67609227
20GRK71.67489480
21DAPK21.62630122
22EPHA41.57990302
23MOS1.54844125
24ARAF1.51716411
25CAMK41.50970884
26LATS21.50296149
27PAK61.48095593
28SGK2231.45590973
29SGK4941.45590973
30PRKD31.37626928
31CAMK2B1.29561550
32CAMKK21.25509699
33MAP3K41.24991335
34ALK1.19700018
35MINK11.19260175
36MAP3K131.19234966
37NTRK21.18836517
38TTK1.15690116
39SGK21.09292146
40PRKG21.06913290
41SGK31.00965859
42PKN11.00420972
43ADRBK11.00189689
44RIPK40.99164684
45CAMK2G0.97658785
46STK380.96259839
47MAPK120.94751072
48TAOK10.92041668
49NEK60.91025347
50HIPK20.89684951
51MAP3K70.89409494
52PAK40.88053217
53SIK20.87523650
54PHKG20.86720249
55PHKG10.86720249
56DAPK10.85886589
57DAPK30.85757061
58PRKCG0.83803901
59MAP2K60.83123039
60CAMK2A0.83117108
61PDPK10.82293022
62MAPKAPK30.82015995
63RIPK10.81923038
64KSR20.81307104
65PAK30.81212972
66PRPF4B0.79903163
67CDK190.78911020
68CAMKK10.78878912
69CDK50.77913652
70AKT30.77466077
71STK100.76765003
72CDK150.75655702
73MAP3K100.73107831
74MAPK130.72938422
75SGK10.72922238
76FGFR30.72311225
77CDK180.71913650
78PINK10.69426546
79CDK11A0.67857936
80LIMK10.67856918
81MAP2K70.67436664
82CDK140.63200548
83LMTK20.59133241
84ROCK20.59081697
85FGFR20.58870786
86RET0.58119447
87CAMK2D0.57955707
88TESK10.57426130
89AKT20.56314708
90DYRK1A0.56126506
91PDGFRA0.55793757
92BRAF0.55617252
93CHEK20.54474666
94ICK0.53533383
95RPS6KA20.50564558
96PRKCH0.50206256
97DYRK20.48814247
98UHMK10.48612300
99MAP3K110.48390732
100CAMK1D0.46712487
101CAMK10.46016359
102EEF2K0.45726406
103STK110.45071951
104CDK70.45066392
105KSR10.42823698
106ROCK10.41107338
107PTK20.40455000
108MAPK100.39997202
109PRKCI0.39691199
110MAP3K10.39154314
111PRKCZ0.39044568
112ERBB20.38317276
113CAMK1G0.37966595
114BRSK10.37537418
115BMX0.36980684
116PRKD10.36697348
117TRIB30.36422009
118SIK10.36407288
119TNK20.34647767
120DDR20.33478012
121PRKD20.32929520
122PAK20.32774587
123RPS6KA30.31738744
124MAPK40.31661708
125PDK10.31376938
126MAP2K10.30548092
127MTOR0.29949404
128BMPR20.29639709
129FES0.29616223
130MAPKAPK50.29411212
131IRAK20.28951311
132NEK10.27979423
133CSNK1E0.27942176
134PLK20.27395719
135OXSR10.25541200
136PRKAA10.24781140
137CHEK10.24707840
138IGF1R0.24701343
139MAP3K20.24438469
140GSK3B0.24078854
141PRKACG0.23487448
142PLK10.22730563
143FYN0.21317585
144CSNK1G20.19526181

Predicted pathways (KEGG)

RankGene SetZ-score
1Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006034.13950763
2Vitamin B6 metabolism_Homo sapiens_hsa007503.15037720
3Olfactory transduction_Homo sapiens_hsa047402.94785160
4Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.61383201
5Synaptic vesicle cycle_Homo sapiens_hsa047212.26411403
6Glutamatergic synapse_Homo sapiens_hsa047242.18184563
7GABAergic synapse_Homo sapiens_hsa047272.07119655
8Long-term potentiation_Homo sapiens_hsa047201.96039745
9Fructose and mannose metabolism_Homo sapiens_hsa000511.96022225
10Nicotine addiction_Homo sapiens_hsa050331.85244127
11Circadian entrainment_Homo sapiens_hsa047131.74890855
12Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.72189608
13Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.66519493
14Taste transduction_Homo sapiens_hsa047421.66334968
15Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.66090621
16mTOR signaling pathway_Homo sapiens_hsa041501.66053126
17Salivary secretion_Homo sapiens_hsa049701.63438905
18Dopaminergic synapse_Homo sapiens_hsa047281.59641877
19Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.58625826
20Morphine addiction_Homo sapiens_hsa050321.51462432
21Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.50330616
22GnRH signaling pathway_Homo sapiens_hsa049121.44386513
23Serotonergic synapse_Homo sapiens_hsa047261.43989254
24Phospholipase D signaling pathway_Homo sapiens_hsa040721.41546050
25Amphetamine addiction_Homo sapiens_hsa050311.35839816
26Long-term depression_Homo sapiens_hsa047301.34967604
27Oxytocin signaling pathway_Homo sapiens_hsa049211.33649458
28Axon guidance_Homo sapiens_hsa043601.31308666
29cAMP signaling pathway_Homo sapiens_hsa040241.25882141
30Gastric acid secretion_Homo sapiens_hsa049711.25245163
31Insulin secretion_Homo sapiens_hsa049111.25017008
32Phosphatidylinositol signaling system_Homo sapiens_hsa040701.24308834
33Calcium signaling pathway_Homo sapiens_hsa040201.23717646
34Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.21920099
35Cholinergic synapse_Homo sapiens_hsa047251.20295483
36Renin secretion_Homo sapiens_hsa049241.18867614
37Aldosterone synthesis and secretion_Homo sapiens_hsa049251.16567452
38Galactose metabolism_Homo sapiens_hsa000521.15980871
39Gap junction_Homo sapiens_hsa045401.11351466
40Ovarian steroidogenesis_Homo sapiens_hsa049131.09603923
41Rap1 signaling pathway_Homo sapiens_hsa040151.04925402
42Choline metabolism in cancer_Homo sapiens_hsa052311.03965891
43Glioma_Homo sapiens_hsa052141.03068453
44Pancreatic secretion_Homo sapiens_hsa049721.00455000
45Prion diseases_Homo sapiens_hsa050200.99920918
46VEGF signaling pathway_Homo sapiens_hsa043700.99565091
47Thyroid hormone signaling pathway_Homo sapiens_hsa049190.98752206
48Arachidonic acid metabolism_Homo sapiens_hsa005900.96808019
49Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.94502173
50Vascular smooth muscle contraction_Homo sapiens_hsa042700.94401830
51Inositol phosphate metabolism_Homo sapiens_hsa005620.93642042
52ErbB signaling pathway_Homo sapiens_hsa040120.93312277
53Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.89202622
54Estrogen signaling pathway_Homo sapiens_hsa049150.84441224
55Regulation of actin cytoskeleton_Homo sapiens_hsa048100.84252482
56Melanogenesis_Homo sapiens_hsa049160.84156616
57Non-small cell lung cancer_Homo sapiens_hsa052230.83724280
58Ras signaling pathway_Homo sapiens_hsa040140.83391371
59cGMP-PKG signaling pathway_Homo sapiens_hsa040220.83125785
60Carbohydrate digestion and absorption_Homo sapiens_hsa049730.81990674
61Neurotrophin signaling pathway_Homo sapiens_hsa047220.81751256
62Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.80049247
63Hedgehog signaling pathway_Homo sapiens_hsa043400.79979071
64Dilated cardiomyopathy_Homo sapiens_hsa054140.78803182
65Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.78540884
66Cocaine addiction_Homo sapiens_hsa050300.77800424
67Thyroid cancer_Homo sapiens_hsa052160.77765524
68Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.77734351
69Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.76818736
70Cardiac muscle contraction_Homo sapiens_hsa042600.76103936
71Dorso-ventral axis formation_Homo sapiens_hsa043200.75957753
72Central carbon metabolism in cancer_Homo sapiens_hsa052300.73264892
73Sphingolipid signaling pathway_Homo sapiens_hsa040710.72129570
74Collecting duct acid secretion_Homo sapiens_hsa049660.70770874
75Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.70249156
76Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.69966845
77Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.69110100
78Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.68952165
79Longevity regulating pathway - mammal_Homo sapiens_hsa042110.68587581
80Endometrial cancer_Homo sapiens_hsa052130.67749357
81Wnt signaling pathway_Homo sapiens_hsa043100.67239657
82Vibrio cholerae infection_Homo sapiens_hsa051100.66176916
83Hippo signaling pathway_Homo sapiens_hsa043900.65479038
84Linoleic acid metabolism_Homo sapiens_hsa005910.64871663
85Oocyte meiosis_Homo sapiens_hsa041140.64630385
86MAPK signaling pathway_Homo sapiens_hsa040100.64079230
87Glucagon signaling pathway_Homo sapiens_hsa049220.64032351
88Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.64018523
89Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.63865741
90alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.63803107
91Colorectal cancer_Homo sapiens_hsa052100.60026740
92Circadian rhythm_Homo sapiens_hsa047100.58013535
93Bile secretion_Homo sapiens_hsa049760.57220955
94Tight junction_Homo sapiens_hsa045300.56454883
95Basal cell carcinoma_Homo sapiens_hsa052170.56272721
96Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.53934063
97Arginine and proline metabolism_Homo sapiens_hsa003300.51392983
98Pathways in cancer_Homo sapiens_hsa052000.51222672
99Endocytosis_Homo sapiens_hsa041440.50274175
100Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.49850458
101Type II diabetes mellitus_Homo sapiens_hsa049300.49690363
102Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.49545297
103AMPK signaling pathway_Homo sapiens_hsa041520.48089073
104Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.47278311
105Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.46586452
106Bladder cancer_Homo sapiens_hsa052190.46396774
107Thyroid hormone synthesis_Homo sapiens_hsa049180.45485554
108Proteoglycans in cancer_Homo sapiens_hsa052050.45073416
109Renal cell carcinoma_Homo sapiens_hsa052110.44661345
110Insulin signaling pathway_Homo sapiens_hsa049100.44395439
111Pancreatic cancer_Homo sapiens_hsa052120.44318260
112Nitrogen metabolism_Homo sapiens_hsa009100.40386020
113Glycerophospholipid metabolism_Homo sapiens_hsa005640.40098094
114mRNA surveillance pathway_Homo sapiens_hsa030150.39440065
115Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.38098807
116Histidine metabolism_Homo sapiens_hsa003400.35121079
117Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.33596497
118Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.33002813
119Focal adhesion_Homo sapiens_hsa045100.32756557
120Alcoholism_Homo sapiens_hsa050340.32595808
121Mineral absorption_Homo sapiens_hsa049780.32357003
122Protein digestion and absorption_Homo sapiens_hsa049740.31867469
123Arginine biosynthesis_Homo sapiens_hsa002200.31814482
124ECM-receptor interaction_Homo sapiens_hsa045120.31302649
125Amoebiasis_Homo sapiens_hsa051460.28976682

Most similar genes based on co-expression Upload to Enrichr

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