NYAP2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)5.85994838
2vocalization behavior (GO:0071625)5.78236574
3synaptic vesicle exocytosis (GO:0016079)5.73840141
4neuron cell-cell adhesion (GO:0007158)5.72637666
5pyrimidine nucleobase catabolic process (GO:0006208)5.47129545
6positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.15011092
7protein localization to synapse (GO:0035418)5.11680447
8regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.06186958
9positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.95037184
10glutamate secretion (GO:0014047)4.90716300
11regulation of inhibitory postsynaptic membrane potential (GO:0060080)4.78748435
12regulation of synaptic vesicle exocytosis (GO:2000300)4.75821911
13synaptic vesicle maturation (GO:0016188)4.74853342
14nucleobase catabolic process (GO:0046113)4.69289335
15regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.59946510
16synaptic vesicle docking involved in exocytosis (GO:0016081)4.55770539
17regulation of glutamate receptor signaling pathway (GO:1900449)4.53326342
18G-protein coupled glutamate receptor signaling pathway (GO:0007216)4.52256519
19neurotransmitter secretion (GO:0007269)4.48786779
20glutamate receptor signaling pathway (GO:0007215)4.48399992
21behavioral response to nicotine (GO:0035095)4.40337397
22ionotropic glutamate receptor signaling pathway (GO:0035235)4.40024591
23neurotransmitter-gated ion channel clustering (GO:0072578)4.36516223
24positive regulation of synapse maturation (GO:0090129)4.31940387
25locomotory exploration behavior (GO:0035641)4.30653734
26neuron-neuron synaptic transmission (GO:0007270)4.23088303
27gamma-aminobutyric acid signaling pathway (GO:0007214)4.17713942
28regulation of synaptic vesicle transport (GO:1902803)4.12652897
29synaptic transmission, glutamatergic (GO:0035249)4.12214910
30presynaptic membrane assembly (GO:0097105)4.04420637
31negative regulation of synaptic transmission, GABAergic (GO:0032229)3.91721755
32startle response (GO:0001964)3.90639677
33postsynaptic membrane organization (GO:0001941)3.85688904
34response to histamine (GO:0034776)3.84699253
35cerebellar Purkinje cell differentiation (GO:0021702)3.82385297
36exploration behavior (GO:0035640)3.81883652
37neuron recognition (GO:0008038)3.81361512
38synaptic vesicle endocytosis (GO:0048488)3.80509429
39regulation of synapse structural plasticity (GO:0051823)3.77424348
40layer formation in cerebral cortex (GO:0021819)3.70514021
41neurotransmitter transport (GO:0006836)3.69501737
42presynaptic membrane organization (GO:0097090)3.67784339
43synapse assembly (GO:0007416)3.67470197
44regulation of postsynaptic membrane potential (GO:0060078)3.66281605
45membrane hyperpolarization (GO:0060081)3.65592721
46behavioral response to cocaine (GO:0048148)3.65372801
47neuronal action potential propagation (GO:0019227)3.64673088
48regulation of excitatory postsynaptic membrane potential (GO:0060079)3.64310574
49regulation of synapse maturation (GO:0090128)3.64292314
50regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.62331872
51regulation of synaptic transmission, glutamatergic (GO:0051966)3.62144048
52regulation of neuronal synaptic plasticity (GO:0048168)3.59260274
53regulation of long-term neuronal synaptic plasticity (GO:0048169)3.57377072
54membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.54489383
55response to pheromone (GO:0019236)3.52482561
56positive regulation of membrane potential (GO:0045838)3.51167248
57positive regulation of action potential (GO:0045760)3.50323766
58regulation of neurotransmitter secretion (GO:0046928)3.48618236
59axonal fasciculation (GO:0007413)3.45976738
60long-term synaptic potentiation (GO:0060291)3.43866058
61regulation of action potential (GO:0098900)3.43807122
62cellular potassium ion homeostasis (GO:0030007)3.42285747
63cerebellar granule cell differentiation (GO:0021707)3.39877147
64innervation (GO:0060384)3.39148725
65gamma-aminobutyric acid transport (GO:0015812)3.38926600
66regulation of neurotransmitter levels (GO:0001505)3.38149647
67negative regulation of cytosolic calcium ion concentration (GO:0051481)3.37284563
68positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.36754263
69negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.36180703
70fucose catabolic process (GO:0019317)3.35320404
71L-fucose metabolic process (GO:0042354)3.35320404
72L-fucose catabolic process (GO:0042355)3.35320404
73long-term memory (GO:0007616)3.34527259
74striatum development (GO:0021756)3.34218560
75tachykinin receptor signaling pathway (GO:0007217)3.31766747
76auditory behavior (GO:0031223)3.30250495
77regulation of vesicle fusion (GO:0031338)3.29952340
78dendritic spine morphogenesis (GO:0060997)3.27782372
79transmission of nerve impulse (GO:0019226)3.27090781
80membrane depolarization during action potential (GO:0086010)3.26880409
81regulation of neurotransmitter transport (GO:0051588)3.23902590
82proline transport (GO:0015824)3.23715273
83regulation of respiratory system process (GO:0044065)3.22629739
84positive regulation of neurotransmitter secretion (GO:0001956)3.22275361
85response to auditory stimulus (GO:0010996)3.21721295
86positive regulation of amino acid transport (GO:0051957)3.21716105
87retinal cone cell development (GO:0046549)3.21677299
88positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.21261686
89glycosphingolipid biosynthetic process (GO:0006688)3.20712091
90membrane depolarization (GO:0051899)3.19587396
91detection of light stimulus involved in sensory perception (GO:0050962)3.19427781
92detection of light stimulus involved in visual perception (GO:0050908)3.19427781
93reflex (GO:0060004)3.17427084
94regulation of voltage-gated calcium channel activity (GO:1901385)3.16490550
95positive regulation of neurotransmitter transport (GO:0051590)3.14850486
96synaptic transmission (GO:0007268)3.14066094
97mating behavior (GO:0007617)3.12937876
98protein polyglutamylation (GO:0018095)3.12705825
99nonmotile primary cilium assembly (GO:0035058)3.12026040
100establishment of mitochondrion localization (GO:0051654)3.11289768
101regulation of synaptic plasticity (GO:0048167)3.11248979
102learning (GO:0007612)3.09749474
103synaptic vesicle transport (GO:0048489)3.09640595
104establishment of synaptic vesicle localization (GO:0097480)3.09640595
105prepulse inhibition (GO:0060134)3.07910449
106positive regulation of synapse assembly (GO:0051965)3.07142687
107positive regulation of synaptic transmission, GABAergic (GO:0032230)3.04764047
108C4-dicarboxylate transport (GO:0015740)3.03354990
109cell migration in hindbrain (GO:0021535)3.03040627
110dendrite morphogenesis (GO:0048813)3.02518715
111neuronal action potential (GO:0019228)3.00655938
112intraspecies interaction between organisms (GO:0051703)2.99153791
113social behavior (GO:0035176)2.99153791
114neural tube formation (GO:0001841)2.98501767
115synapse organization (GO:0050808)2.98335930
116urinary tract smooth muscle contraction (GO:0014848)2.97917251
117cornea development in camera-type eye (GO:0061303)2.97801548
118detection of calcium ion (GO:0005513)2.97739936
119behavioral defense response (GO:0002209)2.97065347
120behavioral fear response (GO:0001662)2.97065347
121mechanosensory behavior (GO:0007638)2.95588670
122protein K11-linked deubiquitination (GO:0035871)2.94870237
123behavioral response to ethanol (GO:0048149)2.94276868
124righting reflex (GO:0060013)2.92881819
125negative regulation of telomere maintenance (GO:0032205)2.92731879
126cellular ketone body metabolic process (GO:0046950)2.92709108
127protein localization to cilium (GO:0061512)2.90364206
128neurofilament cytoskeleton organization (GO:0060052)2.88863972
129DNA deamination (GO:0045006)2.85655026
130cAMP catabolic process (GO:0006198)2.84939556
131dopamine transport (GO:0015872)2.84768953
132DNA double-strand break processing (GO:0000729)2.84123691
133regulation of glucokinase activity (GO:0033131)2.79130237
134regulation of hexokinase activity (GO:1903299)2.79130237
135inositol phosphate catabolic process (GO:0071545)2.76622831
136inner ear receptor stereocilium organization (GO:0060122)2.76618869
137synaptic transmission, cholinergic (GO:0007271)2.71714985
138spinal cord motor neuron differentiation (GO:0021522)2.69185536
139detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.66732762
140positive regulation of oligodendrocyte differentiation (GO:0048714)2.65769165
141platelet dense granule organization (GO:0060155)2.65666726
142axoneme assembly (GO:0035082)2.64988256
143photoreceptor cell development (GO:0042461)2.63827056
144regulation of telomere maintenance (GO:0032204)2.63027450
145protein-cofactor linkage (GO:0018065)2.62902089
146neuromuscular synaptic transmission (GO:0007274)2.62598230
147ketone body metabolic process (GO:1902224)2.62095466
148central nervous system projection neuron axonogenesis (GO:0021952)2.59428185
149piRNA metabolic process (GO:0034587)2.59201121
150regulation of feeding behavior (GO:0060259)2.57449170
151protein complex biogenesis (GO:0070271)2.55955412
152kidney morphogenesis (GO:0060993)2.55038221
153indolalkylamine metabolic process (GO:0006586)2.54469321
154sympathetic nervous system development (GO:0048485)2.54175313
155acrosome reaction (GO:0007340)2.53150936
156cyclic nucleotide catabolic process (GO:0009214)2.52915959
157epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.51857928
158central nervous system neuron axonogenesis (GO:0021955)2.51348251
159alanine transport (GO:0032328)2.50227572
160photoreceptor cell maintenance (GO:0045494)2.49624169
161adult feeding behavior (GO:0008343)2.48725189
162calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.47351341
163retinal ganglion cell axon guidance (GO:0031290)2.47184222
164DNA methylation involved in gamete generation (GO:0043046)2.46990807
165epithelial cilium movement (GO:0003351)2.45583362
166adult behavior (GO:0030534)2.44157698

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.27845690
2GBX2_23144817_ChIP-Seq_PC3_Human4.44820440
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.98230885
4JARID2_20064375_ChIP-Seq_MESCs_Mouse2.96237066
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.89310056
6REST_21632747_ChIP-Seq_MESCs_Mouse2.60529151
7EZH2_27304074_Chip-Seq_ESCs_Mouse2.50135734
8RNF2_18974828_ChIP-Seq_MESCs_Mouse2.48181306
9EZH2_18974828_ChIP-Seq_MESCs_Mouse2.48181306
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.47659337
11SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.46414307
12SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.46146982
13GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.41491285
14TAF15_26573619_Chip-Seq_HEK293_Human2.40294633
15SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.28639628
16MTF2_20144788_ChIP-Seq_MESCs_Mouse2.24939483
17ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.23361236
18EED_16625203_ChIP-ChIP_MESCs_Mouse2.22999696
19SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.22054969
20CTBP2_25329375_ChIP-Seq_LNCAP_Human2.19864530
21DROSHA_22980978_ChIP-Seq_HELA_Human2.17906215
22ZFP57_27257070_Chip-Seq_ESCs_Mouse2.15837930
23SUZ12_27294783_Chip-Seq_ESCs_Mouse2.13568594
24EZH2_27294783_Chip-Seq_ESCs_Mouse2.10154808
25FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.07372139
26CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.06502420
27RNF2_27304074_Chip-Seq_ESCs_Mouse2.04888920
28REST_18959480_ChIP-ChIP_MESCs_Mouse2.03106653
29CTBP1_25329375_ChIP-Seq_LNCAP_Human2.02455675
30RARB_27405468_Chip-Seq_BRAIN_Mouse1.98228678
31GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.98119683
32SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.93528453
33TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.90409358
34NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.89828667
35SALL1_21062744_ChIP-ChIP_HESCs_Human1.88604441
36SMAD4_21799915_ChIP-Seq_A2780_Human1.84141209
37EWS_26573619_Chip-Seq_HEK293_Human1.80629069
38IKZF1_21737484_ChIP-ChIP_HCT116_Human1.79471603
39IGF1R_20145208_ChIP-Seq_DFB_Human1.79283674
40AR_21572438_ChIP-Seq_LNCaP_Human1.78863173
41PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.78385641
42BMI1_23680149_ChIP-Seq_NPCS_Mouse1.75427950
43FLI1_27457419_Chip-Seq_LIVER_Mouse1.73610641
44P300_19829295_ChIP-Seq_ESCs_Human1.73508653
45HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.68805401
46CBX2_27304074_Chip-Seq_ESCs_Mouse1.67257931
47POU3F2_20337985_ChIP-ChIP_501MEL_Human1.63000927
48IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.59359140
49CBP_20019798_ChIP-Seq_JUKART_Human1.59359140
50RNF2_27304074_Chip-Seq_NSC_Mouse1.51349238
51SMAD3_21741376_ChIP-Seq_EPCs_Human1.50820098
52PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.50250232
53E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.47559889
54TP53_22573176_ChIP-Seq_HFKS_Human1.46290909
55RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.45387282
56MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.44776651
57FUS_26573619_Chip-Seq_HEK293_Human1.44736172
58PIAS1_25552417_ChIP-Seq_VCAP_Human1.43062569
59PCGF2_27294783_Chip-Seq_ESCs_Mouse1.42861138
60AR_25329375_ChIP-Seq_VCAP_Human1.41969053
61SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.39996756
62HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.38414586
63SMAD_19615063_ChIP-ChIP_OVARY_Human1.37011390
64TOP2B_26459242_ChIP-Seq_MCF-7_Human1.36202703
65SOX2_21211035_ChIP-Seq_LN229_Gbm1.34083079
66MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.34014070
67STAT3_23295773_ChIP-Seq_U87_Human1.32998472
68P53_22127205_ChIP-Seq_FIBROBLAST_Human1.31334343
69EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.31120061
70ZNF274_21170338_ChIP-Seq_K562_Hela1.30822153
71OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.30459769
72NOTCH1_21737748_ChIP-Seq_TLL_Human1.28955504
73NR3C1_23031785_ChIP-Seq_PC12_Mouse1.27681283
74SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.27279109
75EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.26806210
76NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.26344033
77KLF5_20875108_ChIP-Seq_MESCs_Mouse1.24597634
78TCF4_23295773_ChIP-Seq_U87_Human1.23559592
79IRF1_19129219_ChIP-ChIP_H3396_Human1.22567001
80CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.21982967
81TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.20708069
82GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.19634340
83AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.19488127
84TCF4_22108803_ChIP-Seq_LS180_Human1.18494690
85SUZ12_27294783_Chip-Seq_NPCs_Mouse1.18282005
86RING1B_27294783_Chip-Seq_ESCs_Mouse1.18162623
87AR_19668381_ChIP-Seq_PC3_Human1.17132081
88TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15972416
89POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.15972416
90UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.15358864
91ER_23166858_ChIP-Seq_MCF-7_Human1.14664482
92TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.13699434
93PCGF2_27294783_Chip-Seq_NPCs_Mouse1.12972095
94BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.12279454
95SMAD4_21741376_ChIP-Seq_EPCs_Human1.10159770
96MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.10067757
97NANOG_19829295_ChIP-Seq_ESCs_Human1.10045663
98SOX2_19829295_ChIP-Seq_ESCs_Human1.10045663
99RUNX2_22187159_ChIP-Seq_PCA_Human1.09998373
100CDX2_19796622_ChIP-Seq_MESCs_Mouse1.09185733
101ARNT_22903824_ChIP-Seq_MCF-7_Human1.08415871
102NANOG_18555785_Chip-Seq_ESCs_Mouse1.08237935
103ERG_21242973_ChIP-ChIP_JURKAT_Human1.07780211
104YAP1_20516196_ChIP-Seq_MESCs_Mouse1.07276759
105NFE2_27457419_Chip-Seq_LIVER_Mouse1.07234799
106POU5F1_16153702_ChIP-ChIP_HESCs_Human1.06208758
107JUN_21703547_ChIP-Seq_K562_Human1.04687205
108FLI1_21867929_ChIP-Seq_TH2_Mouse1.04661275
109EZH2_27294783_Chip-Seq_NPCs_Mouse1.04613161
110PRDM14_20953172_ChIP-Seq_ESCs_Human1.04574759
111MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.04454171
112NR3C1_21868756_ChIP-Seq_MCF10A_Human1.04083794
113TAL1_26923725_Chip-Seq_HPCs_Mouse1.02537657
114CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.02515430
115RING1B_27294783_Chip-Seq_NPCs_Mouse1.02088888
116AHR_22903824_ChIP-Seq_MCF-7_Human1.02012618
117MYC_18940864_ChIP-ChIP_HL60_Human1.01626119
118RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.01531343
119TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.01481165
120ZNF217_24962896_ChIP-Seq_MCF-7_Human1.00937573
121FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.00660135
122P53_22387025_ChIP-Seq_ESCs_Mouse0.99894335
123RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.99533106
124TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99364231
125MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.97843621
126VDR_22108803_ChIP-Seq_LS180_Human0.96902870
127BCAT_22108803_ChIP-Seq_LS180_Human0.95854729
128RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.93565045
129E2F1_18555785_Chip-Seq_ESCs_Mouse0.93412256
130SMAD3_21741376_ChIP-Seq_ESCs_Human0.93057248
131VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.92902099
132KDM2B_26808549_Chip-Seq_REH_Human0.92649684
133EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.92539887
134CMYC_18555785_Chip-Seq_ESCs_Mouse0.90946427

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.94862660
2MP0003880_abnormal_central_pattern4.83301665
3MP0003635_abnormal_synaptic_transmissio3.84609556
4MP0009745_abnormal_behavioral_response3.30109436
5MP0009046_muscle_twitch3.24041788
6MP0004270_analgesia3.21753709
7MP0002063_abnormal_learning/memory/cond3.16342992
8MP0002064_seizures3.05272177
9MP0001984_abnormal_olfaction2.97435188
10MP0002572_abnormal_emotion/affect_behav2.84702728
11MP0001968_abnormal_touch/_nociception2.78036295
12MP0005423_abnormal_somatic_nervous2.75383724
13MP0001486_abnormal_startle_reflex2.68986143
14MP0002272_abnormal_nervous_system2.61688969
15MP0002734_abnormal_mechanical_nocicepti2.57647641
16MP0002822_catalepsy2.51467952
17MP0006276_abnormal_autonomic_nervous2.32699901
18MP0001501_abnormal_sleep_pattern2.30013076
19MP0005551_abnormal_eye_electrophysiolog2.23540507
20MP0002184_abnormal_innervation2.22749037
21MP0001188_hyperpigmentation2.22168448
22MP0002735_abnormal_chemical_nociception2.20527769
23MP0008877_abnormal_DNA_methylation2.16331522
24MP0002067_abnormal_sensory_capabilities2.10863776
25MP0002736_abnormal_nociception_after1.98770779
26MP0002557_abnormal_social/conspecific_i1.96694080
27MP0001440_abnormal_grooming_behavior1.95339950
28MP0001529_abnormal_vocalization1.87112426
29MP0000778_abnormal_nervous_system1.86155404
30MP0001502_abnormal_circadian_rhythm1.85991215
31MP0003787_abnormal_imprinting1.84669711
32MP0005645_abnormal_hypothalamus_physiol1.80944633
33MP0001970_abnormal_pain_threshold1.78724450
34MP0005386_behavior/neurological_phenoty1.77376594
35MP0004924_abnormal_behavior1.77376594
36MP0002733_abnormal_thermal_nociception1.76758401
37MP0005646_abnormal_pituitary_gland1.76654247
38MP0003195_calcinosis1.72604056
39MP0003879_abnormal_hair_cell1.68372462
40MP0004811_abnormal_neuron_physiology1.64539174
41MP0000569_abnormal_digit_pigmentation1.61104246
42MP0010386_abnormal_urinary_bladder1.59818897
43MP0008569_lethality_at_weaning1.58067706
44MP0002909_abnormal_adrenal_gland1.56321482
45MP0008875_abnormal_xenobiotic_pharmacok1.53107531
46MP0002882_abnormal_neuron_morphology1.52634698
47MP0003646_muscle_fatigue1.47765118
48MP0004043_abnormal_pH_regulation1.47093934
49MP0001905_abnormal_dopamine_level1.45489937
50MP0002653_abnormal_ependyma_morphology1.45265133
51MP0004742_abnormal_vestibular_system1.44192523
52MP0000955_abnormal_spinal_cord1.43670847
53MP0002638_abnormal_pupillary_reflex1.38819225
54MP0004142_abnormal_muscle_tone1.38743500
55MP0004133_heterotaxia1.35354744
56MP0002066_abnormal_motor_capabilities/c1.35077397
57MP0006072_abnormal_retinal_apoptosis1.34092648
58MP0003122_maternal_imprinting1.32021361
59MP0004858_abnormal_nervous_system1.30130242
60MP0002090_abnormal_vision1.29437361
61MP0006292_abnormal_olfactory_placode1.21781977
62MP0005499_abnormal_olfactory_system1.19863177
63MP0005394_taste/olfaction_phenotype1.19863177
64MP0000372_irregular_coat_pigmentation1.19064954
65MP0002234_abnormal_pharynx_morphology1.18491328
66MP0008995_early_reproductive_senescence1.18163311
67MP0009780_abnormal_chondrocyte_physiolo1.16927382
68MP0000631_abnormal_neuroendocrine_gland1.12982816
69MP0002229_neurodegeneration1.12945184
70MP0002152_abnormal_brain_morphology1.12943744
71MP0002752_abnormal_somatic_nervous1.12751804
72MP0003329_amyloid_beta_deposits1.11275883
73MP0005253_abnormal_eye_physiology1.10310603
74MP0004145_abnormal_muscle_electrophysio1.09131350
75MP0004885_abnormal_endolymph1.06731880
76MP0003633_abnormal_nervous_system1.03170540
77MP0004147_increased_porphyrin_level0.99348473
78MP0005084_abnormal_gallbladder_morpholo0.99278370
79MP0003718_maternal_effect0.99125326
80MP0002277_abnormal_respiratory_mucosa0.97132546
81MP0001963_abnormal_hearing_physiology0.96912037
82MP0002069_abnormal_eating/drinking_beha0.93893523
83MP0003631_nervous_system_phenotype0.91980567
84MP0005409_darkened_coat_color0.90470632
85MP0004233_abnormal_muscle_weight0.87764724
86MP0002938_white_spotting0.85840866
87MP0004085_abnormal_heartbeat0.85282631
88MP0008872_abnormal_physiological_respon0.84830142
89MP0000427_abnormal_hair_cycle0.84689663
90MP0003119_abnormal_digestive_system0.84131669
91MP0001177_atelectasis0.82784436
92MP0004215_abnormal_myocardial_fiber0.81518647
93MP0005195_abnormal_posterior_eye0.80508587
94MP0003698_abnormal_male_reproductive0.80288915
95MP0008789_abnormal_olfactory_epithelium0.79281597
96MP0008874_decreased_physiological_sensi0.76519615
97MP0005187_abnormal_penis_morphology0.76200992
98MP0000751_myopathy0.74106599
99MP0002751_abnormal_autonomic_nervous0.70248502
100MP0000647_abnormal_sebaceous_gland0.68990438
101MP0005391_vision/eye_phenotype0.68608953
102MP0000026_abnormal_inner_ear0.68520389
103MP0002837_dystrophic_cardiac_calcinosis0.66995512
104MP0003136_yellow_coat_color0.66840983
105MP0003011_delayed_dark_adaptation0.66821773
106MP0002876_abnormal_thyroid_physiology0.66778376
107MP0005535_abnormal_body_temperature0.66321349
108MP0001943_abnormal_respiration0.65164900
109MP0003861_abnormal_nervous_system0.63766369
110MP0003121_genomic_imprinting0.63733465
111MP0003634_abnormal_glial_cell0.63241349
112MP0003632_abnormal_nervous_system0.61529511
113MP0001664_abnormal_digestion0.61432089
114MP0002082_postnatal_lethality0.59332952
115MP0010770_preweaning_lethality0.59332952
116MP0001485_abnormal_pinna_reflex0.58633478
117MP0010769_abnormal_survival0.56703657
118MP0001986_abnormal_taste_sensitivity0.54865712
119MP0010768_mortality/aging0.54546389
120MP0003137_abnormal_impulse_conducting0.54277974
121MP0002102_abnormal_ear_morphology0.53335868
122MP0005248_abnormal_Harderian_gland0.51919005
123MP0004484_altered_response_of0.51146092

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.91524164
2Febrile seizures (HP:0002373)5.98093139
3Epileptic encephalopathy (HP:0200134)5.93053520
4Focal seizures (HP:0007359)5.55819614
5Myokymia (HP:0002411)5.06706310
6Congenital stationary night blindness (HP:0007642)5.04817977
7Atonic seizures (HP:0010819)4.90374191
8Absence seizures (HP:0002121)4.76685927
9Hyperventilation (HP:0002883)4.65256660
10Visual hallucinations (HP:0002367)4.54285560
11Dialeptic seizures (HP:0011146)4.31361150
12Progressive cerebellar ataxia (HP:0002073)4.24879166
13Generalized tonic-clonic seizures (HP:0002069)3.85908656
14Pancreatic cysts (HP:0001737)3.79863454
15Broad-based gait (HP:0002136)3.77066858
16Abnormality of midbrain morphology (HP:0002418)3.57181995
17Molar tooth sign on MRI (HP:0002419)3.57181995
18Pancreatic fibrosis (HP:0100732)3.44848872
19True hermaphroditism (HP:0010459)3.32253630
20Gaze-evoked nystagmus (HP:0000640)3.31811811
21Abnormality of macular pigmentation (HP:0008002)3.28654451
22Type II lissencephaly (HP:0007260)3.24750845
23Limb dystonia (HP:0002451)3.22688716
24Drooling (HP:0002307)3.16616700
25Excessive salivation (HP:0003781)3.16616700
26Nephronophthisis (HP:0000090)3.11201025
27Central scotoma (HP:0000603)3.05365856
28Epileptiform EEG discharges (HP:0011182)3.00793298
29Truncal ataxia (HP:0002078)2.96196824
30Severe visual impairment (HP:0001141)2.93972953
31Poor eye contact (HP:0000817)2.87822400
32EEG with generalized epileptiform discharges (HP:0011198)2.84758427
33Action tremor (HP:0002345)2.83674299
34Absent speech (HP:0001344)2.81110192
35Gait imbalance (HP:0002141)2.79474031
36Retinal dysplasia (HP:0007973)2.75983184
37Dysdiadochokinesis (HP:0002075)2.71574558
38Amblyopia (HP:0000646)2.71446053
39Impaired social interactions (HP:0000735)2.71086009
40Abnormal social behavior (HP:0012433)2.71086009
41Protruding tongue (HP:0010808)2.65481628
42Pendular nystagmus (HP:0012043)2.62833317
43Mutism (HP:0002300)2.62204891
44Pachygyria (HP:0001302)2.60910246
45Hemiparesis (HP:0001269)2.60632822
46Abnormality of the renal medulla (HP:0100957)2.59973335
47Abnormality of the labia minora (HP:0012880)2.59220158
48Abolished electroretinogram (ERG) (HP:0000550)2.59156902
49Genetic anticipation (HP:0003743)2.56806891
50Abnormality of the renal cortex (HP:0011035)2.55364007
51Hypsarrhythmia (HP:0002521)2.53031978
52Depression (HP:0000716)2.51614038
53Attenuation of retinal blood vessels (HP:0007843)2.51530641
54Anxiety (HP:0000739)2.49388733
55Inability to walk (HP:0002540)2.48341243
56Fetal akinesia sequence (HP:0001989)2.47662340
57Decreased central vision (HP:0007663)2.47004633
58Ankle clonus (HP:0011448)2.41370094
59Urinary bladder sphincter dysfunction (HP:0002839)2.40676677
60Medial flaring of the eyebrow (HP:0010747)2.40550397
61Congenital primary aphakia (HP:0007707)2.40153421
62Polyphagia (HP:0002591)2.37479501
63Progressive inability to walk (HP:0002505)2.36644838
64Renal cortical cysts (HP:0000803)2.35206696
65Abnormal eating behavior (HP:0100738)2.34058034
66Nephrogenic diabetes insipidus (HP:0009806)2.33723518
67Chronic hepatic failure (HP:0100626)2.31215951
68Cerebellar dysplasia (HP:0007033)2.30793784
69Impaired smooth pursuit (HP:0007772)2.30231854
70Blue irides (HP:0000635)2.28783362
713-Methylglutaconic aciduria (HP:0003535)2.28686425
72Abnormal rod and cone electroretinograms (HP:0008323)2.26679864
73Acute necrotizing encephalopathy (HP:0006965)2.26540450
74Oligodactyly (hands) (HP:0001180)2.22696171
75Dysmetria (HP:0001310)2.21959133
76Impaired vibration sensation in the lower limbs (HP:0002166)2.21075613
77Supranuclear gaze palsy (HP:0000605)2.20413003
78Abnormal hair whorl (HP:0010721)2.20268419
79Cystic liver disease (HP:0006706)2.17982056
80Progressive macrocephaly (HP:0004481)2.16717222
81Intestinal atresia (HP:0011100)2.16498256
82Postural instability (HP:0002172)2.13278462
83Torticollis (HP:0000473)2.12145981
84Pheochromocytoma (HP:0002666)2.11278020
85Specific learning disability (HP:0001328)2.10667469
86Sclerocornea (HP:0000647)2.09952431
87Stereotypic behavior (HP:0000733)2.09118627
88Abnormality of salivation (HP:0100755)2.08123303
89Anencephaly (HP:0002323)2.05533548
90Abnormality of ocular smooth pursuit (HP:0000617)2.05170066
91Dysmetric saccades (HP:0000641)2.04710176
92Aplasia/Hypoplasia of the tibia (HP:0005772)2.03071826
93Polydipsia (HP:0001959)2.02730337
94Abnormal drinking behavior (HP:0030082)2.02730337
95Scanning speech (HP:0002168)1.99691347
96Abnormal mitochondria in muscle tissue (HP:0008316)1.99358154
97Generalized myoclonic seizures (HP:0002123)1.98705900
98Abnormal biliary tract physiology (HP:0012439)1.98533515
99Bile duct proliferation (HP:0001408)1.98533515
100Agitation (HP:0000713)1.96951689
101Postaxial hand polydactyly (HP:0001162)1.96376169
102Ketoacidosis (HP:0001993)1.96294871
103Optic disc pallor (HP:0000543)1.96141738
104Optic nerve hypoplasia (HP:0000609)1.94940053
105Status epilepticus (HP:0002133)1.94258494
106Exotropia (HP:0000577)1.94022854
107Tubular atrophy (HP:0000092)1.93591332
108Widely spaced teeth (HP:0000687)1.92824282
109Polymicrogyria (HP:0002126)1.92765807
110Acute encephalopathy (HP:0006846)1.92183819
111Methylmalonic acidemia (HP:0002912)1.92131606
112Focal dystonia (HP:0004373)1.91685655
113Spastic gait (HP:0002064)1.90888212
114Bradykinesia (HP:0002067)1.89408913
115Hypothermia (HP:0002045)1.89129613
116Incomplete penetrance (HP:0003829)1.87976378
117Mitochondrial inheritance (HP:0001427)1.87666760
118Genital tract atresia (HP:0001827)1.87653710
119Narrow forehead (HP:0000341)1.87193807
120Scotoma (HP:0000575)1.86765485
121Vaginal atresia (HP:0000148)1.86132732
122Abnormality of binocular vision (HP:0011514)1.85307861
123Diplopia (HP:0000651)1.85307861
124Prolonged QT interval (HP:0001657)1.84623414
125Hyperthyroidism (HP:0000836)1.83371438
126Lissencephaly (HP:0001339)1.82088267
127Inappropriate behavior (HP:0000719)1.82036051
128Postaxial foot polydactyly (HP:0001830)1.82012390
129Severe muscular hypotonia (HP:0006829)1.81679719
130Occipital encephalocele (HP:0002085)1.81311409
131Septo-optic dysplasia (HP:0100842)1.80279587
132Poor coordination (HP:0002370)1.79609720
133Neuroendocrine neoplasm (HP:0100634)1.78177022
134Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.77865249
135Aplasia/Hypoplasia of the brainstem (HP:0007362)1.77071450
136Hypoplasia of the brainstem (HP:0002365)1.77071450
137Male pseudohermaphroditism (HP:0000037)1.76691815
138Spastic tetraplegia (HP:0002510)1.76456042
139Increased CSF lactate (HP:0002490)1.75996703
140Keratoconus (HP:0000563)1.75924611
141Increased corneal curvature (HP:0100692)1.75924611
142Abnormality of the corticospinal tract (HP:0002492)1.75902532
143Muscular hypotonia of the trunk (HP:0008936)1.75222603
144Short tibia (HP:0005736)1.74571147
145Aplasia/Hypoplasia of the tongue (HP:0010295)1.74214910
146Urinary urgency (HP:0000012)1.73779747
147Generalized hypopigmentation of hair (HP:0011358)1.73501146
148Patellar aplasia (HP:0006443)1.73046763
149Anterior segment dysgenesis (HP:0007700)1.72734996
150Craniofacial dystonia (HP:0012179)1.72716599
151Bony spicule pigmentary retinopathy (HP:0007737)1.72580897
152Ketosis (HP:0001946)1.72367797
153Retinitis pigmentosa (HP:0000510)1.71345821
154Aplasia/Hypoplasia of the lens (HP:0008063)1.69934332
155Hypoventilation (HP:0002791)1.69674903
156Thickened helices (HP:0000391)1.69666063
157Failure to thrive in infancy (HP:0001531)1.68871933
158Autism (HP:0000717)1.68782942

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK4.27909335
2FRK4.23680027
3NTRK33.96244572
4MAP3K43.76228362
5MARK13.71553077
6MAP2K73.47933150
7EPHA43.35086490
8MAP3K92.65722880
9MINK12.51793946
10MAP4K22.44090551
11TRIM282.37969528
12MAP3K122.31486315
13DAPK22.14766605
14NTRK22.11364251
15MAP2K42.07853885
16PAK61.92902425
17MAPK131.81653922
18PRPF4B1.81119780
19SIK31.74711480
20TNIK1.68466334
21SIK21.62257405
22PNCK1.57455163
23PLK21.56869912
24GRK11.52181022
25KSR11.50637738
26DAPK11.47624527
27GRK51.47205608
28CSNK1G11.38530790
29CDK51.38404847
30ZAK1.33284106
31WNK41.31071909
32NUAK11.28329670
33CDK191.25946784
34CAMKK21.25437851
35PRKCG1.20941626
36CAMKK11.20454334
37AKT31.20223630
38ACVR1B1.18661139
39CCNB11.17117089
40PHKG11.15383256
41PHKG21.15383256
42CAMK2A1.15016292
43MAP3K61.13581299
44SGK4941.08200978
45SGK2231.08200978
46TXK1.04288624
47SGK21.03684411
48RIPK41.03615704
49FES1.01689335
50CSNK1G20.98528978
51STK380.98342036
52MKNK20.94506366
53NTRK10.94195066
54WNK30.93202719
55UHMK10.92386377
56STK390.91626854
57DYRK1A0.90294352
58CDK180.89478668
59KSR20.87715920
60CAMK2B0.86874903
61BCR0.86772859
62ARAF0.86650343
63TAOK10.85129568
64CAMK10.84341516
65CDK140.82876723
66CDK150.82163916
67CDK30.81128612
68BMPR20.79724783
69OBSCN0.77957052
70BCKDK0.76667930
71DYRK30.73846772
72ERBB30.72759022
73PRKCE0.72657946
74OXSR10.72032586
75CDK11A0.70314825
76CAMK1G0.66733806
77CAMK2D0.66463779
78NME10.65724136
79SRPK10.65238152
80INSRR0.65152067
81PAK30.64637698
82SGK10.63720156
83EPHA30.63233524
84TNK20.62745390
85TAOK30.62711766
86GRK70.62234305
87SGK30.61708109
88STK110.60318821
89CSNK1G30.60292652
90STK38L0.57912970
91TLK10.56345006
92MARK20.53745065
93EIF2AK30.53343686
94PRKAA10.53074116
95PKN10.52536211
96FGFR20.51450869
97BRAF0.49941046
98PTK2B0.49734106
99CAMK40.49198829
100ADRBK20.48256125
101RET0.48247066
102PRKCZ0.47841731
103MAP3K20.46976546
104PINK10.46427489
105TGFBR10.46245317
106CAMK2G0.46110390
107LATS20.45345268
108CSNK1A10.45317551
109RPS6KA30.45298690
110LIMK10.45199632
111CSNK1A1L0.43383108
112ADRBK10.43361719
113FGR0.43062292
114MAP3K130.42493569
115FER0.42470234
116PRKG10.42203717
117CSNK1D0.40808064
118PRKCH0.40773336
119DYRK20.40277021
120PRKCB0.39116320
121IRAK20.38914419
122PRKACA0.38614663
123VRK10.37576218
124MAPK100.37437971
125PRKD30.37138638
126MUSK0.36412879
127PRKACB0.35311892
128BMPR1B0.34716550
129MAPKAPK50.34448056
130TAOK20.34314427
131TYRO30.33870362
132MKNK10.33416332
133TIE10.32994258
134RPS6KA50.32549453
135CSNK1E0.32440556
136PIM20.30816899
137PRKCA0.30382280
138MAP2K60.29772021
139PRKCI0.28291365

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.52966112
2Synaptic vesicle cycle_Homo sapiens_hsa047213.71088307
3GABAergic synapse_Homo sapiens_hsa047273.11696125
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047233.02393245
5Olfactory transduction_Homo sapiens_hsa047402.97633660
6Morphine addiction_Homo sapiens_hsa050322.84900406
7Circadian entrainment_Homo sapiens_hsa047132.75286360
8Glutamatergic synapse_Homo sapiens_hsa047242.55483349
9Maturity onset diabetes of the young_Homo sapiens_hsa049502.53149115
10Amphetamine addiction_Homo sapiens_hsa050312.31942988
11Long-term potentiation_Homo sapiens_hsa047202.31102906
12Dopaminergic synapse_Homo sapiens_hsa047282.21084943
13Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.17430220
14Serotonergic synapse_Homo sapiens_hsa047262.10313917
15Salivary secretion_Homo sapiens_hsa049702.08274599
16Insulin secretion_Homo sapiens_hsa049112.08015771
17Cholinergic synapse_Homo sapiens_hsa047252.04392650
18Taste transduction_Homo sapiens_hsa047422.01413279
19Collecting duct acid secretion_Homo sapiens_hsa049661.99329587
20Linoleic acid metabolism_Homo sapiens_hsa005911.96222053
21Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.95039852
22Protein export_Homo sapiens_hsa030601.94751460
23alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.93866753
24Renin secretion_Homo sapiens_hsa049241.80573767
25Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.78083172
26Basal transcription factors_Homo sapiens_hsa030221.75650625
27Phototransduction_Homo sapiens_hsa047441.72688219
28Cocaine addiction_Homo sapiens_hsa050301.68612629
29Aldosterone synthesis and secretion_Homo sapiens_hsa049251.68495368
30Long-term depression_Homo sapiens_hsa047301.65598313
31Oxytocin signaling pathway_Homo sapiens_hsa049211.63720962
32Nitrogen metabolism_Homo sapiens_hsa009101.63541343
33Calcium signaling pathway_Homo sapiens_hsa040201.60747678
34Ether lipid metabolism_Homo sapiens_hsa005651.56517285
35Regulation of autophagy_Homo sapiens_hsa041401.51252879
36Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.50074835
37Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.49268738
38Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.47223662
39Gastric acid secretion_Homo sapiens_hsa049711.43839836
40Selenocompound metabolism_Homo sapiens_hsa004501.40413883
41Gap junction_Homo sapiens_hsa045401.33044632
42GnRH signaling pathway_Homo sapiens_hsa049121.31397644
43Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.23064337
44Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.21390146
45Axon guidance_Homo sapiens_hsa043601.21221233
46cAMP signaling pathway_Homo sapiens_hsa040241.20782669
47Vibrio cholerae infection_Homo sapiens_hsa051101.18656739
48Tryptophan metabolism_Homo sapiens_hsa003801.18203834
49RNA polymerase_Homo sapiens_hsa030201.16717890
50Cardiac muscle contraction_Homo sapiens_hsa042601.16038751
51Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.15053394
52Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.14627545
53Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.11400806
54Propanoate metabolism_Homo sapiens_hsa006401.06226299
55Circadian rhythm_Homo sapiens_hsa047101.02469704
56Type II diabetes mellitus_Homo sapiens_hsa049301.01881572
57cGMP-PKG signaling pathway_Homo sapiens_hsa040221.00005123
58Phosphatidylinositol signaling system_Homo sapiens_hsa040700.99679318
59Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.99238181
60ErbB signaling pathway_Homo sapiens_hsa040120.98150493
61Fanconi anemia pathway_Homo sapiens_hsa034600.97181914
62ABC transporters_Homo sapiens_hsa020100.94695085
63Huntingtons disease_Homo sapiens_hsa050160.93037603
64Estrogen signaling pathway_Homo sapiens_hsa049150.91224090
65Glioma_Homo sapiens_hsa052140.89043514
66Vascular smooth muscle contraction_Homo sapiens_hsa042700.88440175
67Caffeine metabolism_Homo sapiens_hsa002320.87304153
68Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.87081458
69Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.82993174
70RNA degradation_Homo sapiens_hsa030180.82105063
71Peroxisome_Homo sapiens_hsa041460.81820011
72Dilated cardiomyopathy_Homo sapiens_hsa054140.80897703
73Type I diabetes mellitus_Homo sapiens_hsa049400.80607049
74Steroid biosynthesis_Homo sapiens_hsa001000.77876094
75Melanogenesis_Homo sapiens_hsa049160.77028527
76Steroid hormone biosynthesis_Homo sapiens_hsa001400.73536331
77Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.71537996
78Primary bile acid biosynthesis_Homo sapiens_hsa001200.71394738
79Alcoholism_Homo sapiens_hsa050340.70992518
80Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.70865600
81MAPK signaling pathway_Homo sapiens_hsa040100.70812452
82Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.68745430
83Oocyte meiosis_Homo sapiens_hsa041140.68337751
84Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.66761442
85Chemical carcinogenesis_Homo sapiens_hsa052040.65571423
86Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.64804788
87Alzheimers disease_Homo sapiens_hsa050100.64163653
88Choline metabolism in cancer_Homo sapiens_hsa052310.63995089
89Sulfur metabolism_Homo sapiens_hsa009200.63358386
90Phospholipase D signaling pathway_Homo sapiens_hsa040720.63167460
91Pancreatic secretion_Homo sapiens_hsa049720.62304718
92Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.60924225
93Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.58512242
94Oxidative phosphorylation_Homo sapiens_hsa001900.57786296
95Ras signaling pathway_Homo sapiens_hsa040140.57257826
96beta-Alanine metabolism_Homo sapiens_hsa004100.56897285
97Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.56713959
98Dorso-ventral axis formation_Homo sapiens_hsa043200.56659885
99Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.56614956
100Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.54155353
101Thyroid hormone synthesis_Homo sapiens_hsa049180.53837845
102Retinol metabolism_Homo sapiens_hsa008300.52492672
103Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.52150204
104Inositol phosphate metabolism_Homo sapiens_hsa005620.52059935
105Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.49645046
106Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.49050780
107Homologous recombination_Homo sapiens_hsa034400.48148318
108Purine metabolism_Homo sapiens_hsa002300.47408342
109Metabolic pathways_Homo sapiens_hsa011000.47379301
110Arachidonic acid metabolism_Homo sapiens_hsa005900.46363601
111Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.45582184
112Glucagon signaling pathway_Homo sapiens_hsa049220.44510794
113Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.44359539
114Rheumatoid arthritis_Homo sapiens_hsa053230.43677929
115Fatty acid elongation_Homo sapiens_hsa000620.42885637
116Neurotrophin signaling pathway_Homo sapiens_hsa047220.42089707
117Endometrial cancer_Homo sapiens_hsa052130.41683274
118Rap1 signaling pathway_Homo sapiens_hsa040150.41332721
119Wnt signaling pathway_Homo sapiens_hsa043100.40931176
120African trypanosomiasis_Homo sapiens_hsa051430.40105534
121Thyroid hormone signaling pathway_Homo sapiens_hsa049190.39943741
122Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.39569197
123Fat digestion and absorption_Homo sapiens_hsa049750.38684263
124Parkinsons disease_Homo sapiens_hsa050120.38250175
125Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.38167002
126Mineral absorption_Homo sapiens_hsa049780.37929674
127Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.37270333
128SNARE interactions in vesicular transport_Homo sapiens_hsa041300.37250463
129Fatty acid metabolism_Homo sapiens_hsa012120.36941712
130Sphingolipid signaling pathway_Homo sapiens_hsa040710.36338755
131Ovarian steroidogenesis_Homo sapiens_hsa049130.35935090
132Renal cell carcinoma_Homo sapiens_hsa052110.35510707
133Carbohydrate digestion and absorption_Homo sapiens_hsa049730.35111736
134Colorectal cancer_Homo sapiens_hsa052100.34826908
135VEGF signaling pathway_Homo sapiens_hsa043700.33206347
136mTOR signaling pathway_Homo sapiens_hsa041500.32839346
137Non-homologous end-joining_Homo sapiens_hsa034500.32180595
138Fatty acid biosynthesis_Homo sapiens_hsa000610.32136155
139Phagosome_Homo sapiens_hsa041450.31360171
140One carbon pool by folate_Homo sapiens_hsa006700.29275194
141Longevity regulating pathway - mammal_Homo sapiens_hsa042110.28675442
142Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.27170424
143Insulin signaling pathway_Homo sapiens_hsa049100.26839203
144Melanoma_Homo sapiens_hsa052180.26602618
145Butanoate metabolism_Homo sapiens_hsa006500.26549531
146Non-small cell lung cancer_Homo sapiens_hsa052230.26048240
147Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.25927880
148Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.25395077
149Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.25214016
150Hedgehog signaling pathway_Homo sapiens_hsa043400.25170254
151Proteasome_Homo sapiens_hsa030500.24116141
152Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.23551579
153Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.22539765

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