OAF

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1L-phenylalanine catabolic process (GO:0006559)7.27500644
2erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.27500644
3L-phenylalanine metabolic process (GO:0006558)7.03494787
4erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)7.03494787
5aromatic amino acid family catabolic process (GO:0009074)6.51367301
6triglyceride-rich lipoprotein particle remodeling (GO:0034370)6.19522884
7indole-containing compound catabolic process (GO:0042436)5.84571114
8indolalkylamine catabolic process (GO:0046218)5.84571114
9tryptophan catabolic process (GO:0006569)5.84571114
10negative regulation of fibrinolysis (GO:0051918)5.76211921
11kynurenine metabolic process (GO:0070189)5.75548259
12bile acid biosynthetic process (GO:0006699)5.71341128
13glyoxylate metabolic process (GO:0046487)5.63886100
14tryptophan metabolic process (GO:0006568)5.50121194
15regulation of fibrinolysis (GO:0051917)5.48124644
16alpha-linolenic acid metabolic process (GO:0036109)5.46994343
17protein carboxylation (GO:0018214)5.41948718
18peptidyl-glutamic acid carboxylation (GO:0017187)5.41948718
19urea cycle (GO:0000050)5.41464869
20urea metabolic process (GO:0019627)5.41464869
21high-density lipoprotein particle remodeling (GO:0034375)5.41197739
22sulfur amino acid catabolic process (GO:0000098)5.32606113
23cysteine metabolic process (GO:0006534)5.28257674
24regulation of protein activation cascade (GO:2000257)5.20884429
25complement activation, alternative pathway (GO:0006957)5.15672193
26epoxygenase P450 pathway (GO:0019373)5.14863558
27nitrogen cycle metabolic process (GO:0071941)4.98421993
28serine family amino acid catabolic process (GO:0009071)4.92532057
29regulation of complement activation (GO:0030449)4.89147064
30bile acid metabolic process (GO:0008206)4.83848884
31reverse cholesterol transport (GO:0043691)4.79901604
32homocysteine metabolic process (GO:0050667)4.78563043
33regulation of cholesterol esterification (GO:0010872)4.72529398
34aromatic amino acid family metabolic process (GO:0009072)4.71306815
35regulation of triglyceride catabolic process (GO:0010896)4.68281448
36fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.66451839
37macromolecular complex remodeling (GO:0034367)4.66127786
38plasma lipoprotein particle remodeling (GO:0034369)4.66127786
39protein-lipid complex remodeling (GO:0034368)4.66127786
40tyrosine metabolic process (GO:0006570)4.58397137
41lysine catabolic process (GO:0006554)4.57598969
42lysine metabolic process (GO:0006553)4.57598969
43amino-acid betaine metabolic process (GO:0006577)4.48698689
44alpha-amino acid catabolic process (GO:1901606)4.48403295
45acylglycerol homeostasis (GO:0055090)4.47137189
46triglyceride homeostasis (GO:0070328)4.47137189
47glycine metabolic process (GO:0006544)4.42473843
48negative regulation of cholesterol transport (GO:0032375)4.41565829
49negative regulation of sterol transport (GO:0032372)4.41565829
50phospholipid efflux (GO:0033700)4.36111365
51plasma lipoprotein particle clearance (GO:0034381)4.34139755
52cellular glucuronidation (GO:0052695)4.32014799
53exogenous drug catabolic process (GO:0042738)4.31145326
54coenzyme catabolic process (GO:0009109)4.27865100
55cellular ketone body metabolic process (GO:0046950)4.22028319
56serine family amino acid biosynthetic process (GO:0009070)4.20771775
57serine family amino acid metabolic process (GO:0009069)4.18403835
58fibrinolysis (GO:0042730)4.17604736
59bile acid and bile salt transport (GO:0015721)4.15781923
60glutamate metabolic process (GO:0006536)4.15164021
61omega-hydroxylase P450 pathway (GO:0097267)4.15020449
62cellular amino acid catabolic process (GO:0009063)4.14333458
63imidazole-containing compound metabolic process (GO:0052803)4.10733743
64cellular modified amino acid catabolic process (GO:0042219)4.10709812
65amine catabolic process (GO:0009310)4.10094764
66cellular biogenic amine catabolic process (GO:0042402)4.10094764
67indolalkylamine metabolic process (GO:0006586)4.08883037
68ethanol oxidation (GO:0006069)4.02427313
69negative regulation of hemostasis (GO:1900047)4.01886626
70negative regulation of blood coagulation (GO:0030195)4.01886626
71cholesterol efflux (GO:0033344)4.01673424
72drug metabolic process (GO:0017144)3.94642910
73plasma lipoprotein particle assembly (GO:0034377)3.93906431
74low-density lipoprotein particle remodeling (GO:0034374)3.93745390
75dicarboxylic acid biosynthetic process (GO:0043650)3.90724230
76arginine metabolic process (GO:0006525)3.90340180
77benzene-containing compound metabolic process (GO:0042537)3.89571733
78aldehyde catabolic process (GO:0046185)3.84749314
79acute-phase response (GO:0006953)3.83342713
80glucuronate metabolic process (GO:0019585)3.82883863
81uronic acid metabolic process (GO:0006063)3.82883863
82negative regulation of coagulation (GO:0050819)3.80724625
83regulation of plasminogen activation (GO:0010755)3.79065877
84positive regulation of fatty acid beta-oxidation (GO:0032000)3.73800239
85very-low-density lipoprotein particle assembly (GO:0034379)3.73357897
86positive regulation of lipid catabolic process (GO:0050996)3.71902485
87regulation of cholesterol homeostasis (GO:2000188)3.69832740
88blood coagulation, intrinsic pathway (GO:0007597)3.68755909
89cofactor catabolic process (GO:0051187)3.68211876
90ethanol metabolic process (GO:0006067)3.65603269
91ketone body metabolic process (GO:1902224)3.63994892
92intestinal cholesterol absorption (GO:0030299)3.63866901
93negative regulation of wound healing (GO:0061045)3.63800089
94cholesterol homeostasis (GO:0042632)3.63743400
95negative regulation of lipase activity (GO:0060192)3.63130709
96negative regulation of protein activation cascade (GO:2000258)3.62093198
97carboxylic acid catabolic process (GO:0046395)3.61707959
98organic acid catabolic process (GO:0016054)3.61707959
99complement activation, classical pathway (GO:0006958)3.60543342
100protein-lipid complex assembly (GO:0065005)3.60303183
101positive regulation of triglyceride lipase activity (GO:0061365)3.60151903
102positive regulation of lipoprotein lipase activity (GO:0051006)3.60151903
103protein activation cascade (GO:0072376)3.59583434
104complement activation (GO:0006956)3.59379800
105sterol homeostasis (GO:0055092)3.58495517
106plasma lipoprotein particle organization (GO:0071827)3.57905339
107regulation of bile acid biosynthetic process (GO:0070857)3.57286989
108phospholipid homeostasis (GO:0055091)3.56523035
109short-chain fatty acid metabolic process (GO:0046459)3.55470034
110acetyl-CoA metabolic process (GO:0006084)3.53131367
111cytolysis (GO:0019835)3.51450382
112intestinal absorption (GO:0050892)3.49771368
113drug catabolic process (GO:0042737)3.48487616
114basement membrane organization (GO:0071711)3.45454788
115positive regulation of fatty acid biosynthetic process (GO:0045723)3.43353616
116regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)3.38569862
117positive regulation of extracellular matrix organization (GO:1903055)3.37630089
118negative regulation of complement activation (GO:0045916)3.27773766
119protein-lipid complex subunit organization (GO:0071825)3.26989150
120regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.23125894
121positive regulation of hemostasis (GO:1900048)3.17759279
122positive regulation of blood coagulation (GO:0030194)3.17759279
123proline metabolic process (GO:0006560)3.16871881
124regulation of apoptotic cell clearance (GO:2000425)3.15632133
125hormone catabolic process (GO:0042447)3.15113622
126lipoprotein metabolic process (GO:0042157)3.09732395
127regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.06998552
128regulation of humoral immune response (GO:0002920)3.02972400
129adhesion of symbiont to host (GO:0044406)3.02238428
130fat-soluble vitamin biosynthetic process (GO:0042362)2.97737808
131positive regulation of coagulation (GO:0050820)2.95875001
132acute inflammatory response (GO:0002526)2.94032903
133positive regulation of triglyceride metabolic process (GO:0090208)2.92995871
134diacylglycerol metabolic process (GO:0046339)2.92209558
135flavonoid metabolic process (GO:0009812)2.85887790
136opsonization (GO:0008228)2.84418087
137low-density lipoprotein particle clearance (GO:0034383)2.84280538
138renal system process involved in regulation of systemic arterial blood pressure (GO:0003071)2.82340881
139phenylpropanoid metabolic process (GO:0009698)2.81652154
140protein heterotrimerization (GO:0070208)2.79325205
141glutamine family amino acid biosynthetic process (GO:0009084)2.76906692

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* RXR_22158963_ChIP-Seq_LIVER_Mouse8.20315675
2* PPARA_22158963_ChIP-Seq_LIVER_Mouse7.04843848
3EGR1_23403033_ChIP-Seq_LIVER_Mouse6.51091900
4* LXR_22158963_ChIP-Seq_LIVER_Mouse6.33491570
5PPARG_19300518_ChIP-PET_3T3-L1_Mouse5.21323406
6* FOXO1_23066095_ChIP-Seq_LIVER_Mouse4.91859882
7CEBPA_23403033_ChIP-Seq_LIVER_Mouse4.85949450
8NR1I2_20693526_ChIP-Seq_LIVER_Mouse3.94977144
9CEBPB_23403033_ChIP-Seq_LIVER_Mouse3.70452093
10TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.39432741
11* ELK3_25401928_ChIP-Seq_HUVEC_Human2.31764554
12CLOCK_20551151_ChIP-Seq_293T_Human2.22954899
13HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.05716439
14TCF7L2_21901280_ChIP-Seq_H4IIE_Rat2.00560831
15ESR1_17901129_ChIP-ChIP_LIVER_Mouse11.7535570
16RARG_19884340_ChIP-ChIP_MEFs_Mouse1.88804390
17TRIM28_21343339_ChIP-Seq_HEK293_Human1.70740486
18PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.64957818
19TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.60322707
20TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.55297187
21FOXA2_19822575_ChIP-Seq_HepG2_Human1.53535332
22UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.44538885
23THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.37806209
24TET1_21451524_ChIP-Seq_MESCs_Mouse1.36087839
25KDM2B_26808549_Chip-Seq_SUP-B15_Human1.34437533
26VDR_21846776_ChIP-Seq_THP-1_Human1.34083462
27HNF4A_19822575_ChIP-Seq_HepG2_Human1.33901834
28MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.33660962
29ESR1_15608294_ChIP-ChIP_MCF-7_Human1.32508262
30GATA2_21666600_ChIP-Seq_HMVEC_Human1.27911998
31CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.25823327
32KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.25247475
33TP53_22127205_ChIP-Seq_IMR90_Human1.22043690
34TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.21163763
35HTT_18923047_ChIP-ChIP_STHdh_Human1.20666276
36KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.18766418
37STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.16517759
38SMC1_22415368_ChIP-Seq_MEFs_Mouse1.15117069
39* DNAJC2_21179169_ChIP-ChIP_NT2_Human1.13869469
40GATA1_22025678_ChIP-Seq_K562_Human1.13222187
41KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.10764414
42ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.10543599
43* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.10457517
44SA1_27219007_Chip-Seq_ERYTHROID_Human1.09239092
45RXRA_24833708_ChIP-Seq_LIVER_Mouse1.07846825
46P68_20966046_ChIP-Seq_HELA_Human1.07007620
47CTCF_27219007_Chip-Seq_ERYTHROID_Human1.06640655
48STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.06561196
49ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.06301894
50SRY_22984422_ChIP-ChIP_TESTIS_Rat1.03456049
51KDM2B_26808549_Chip-Seq_K562_Human1.02334547
52SMC4_20622854_ChIP-Seq_HELA_Human1.01888089
53UBF1/2_26484160_Chip-Seq_HMECs_Human1.00086035
54* CTCF_27219007_Chip-Seq_Bcells_Human0.99202147
55* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.98925974
56* ZNF263_19887448_ChIP-Seq_K562_Human0.98849324
57HIF1A_21447827_ChIP-Seq_MCF-7_Human0.98118188
58EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.96334250
59CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.94844209
60ELF1_20517297_ChIP-Seq_JURKAT_Human0.94229762
61SALL4_18804426_ChIP-ChIP_XEN_Mouse0.94034024
62JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.93984928
63NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.93562939
64NRF2_20460467_ChIP-Seq_MEFs_Mouse0.93562939
65SA1_27219007_Chip-Seq_Bcells_Human0.92697689
66RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.92100595
67TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.91952597
68* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.91865946
69BCL6_27268052_Chip-Seq_Bcells_Human0.91597633
70SOX2_27498859_Chip-Seq_STOMACH_Mouse0.91546563
71KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.91040754
72BCOR_27268052_Chip-Seq_Bcells_Human0.90635195
73VDR_24763502_ChIP-Seq_THP-1_Human0.89991141
74RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.87881181
75SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.87852151
76NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.87248843
77* JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.86901661
78* JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.84931669
79GATA4_25053715_ChIP-Seq_YYC3_Human0.84381858
80ESR2_21235772_ChIP-Seq_MCF-7_Human0.83312324
81* LXR_22292898_ChIP-Seq_THP-1_Human0.79998153
82BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.78013411
83STAT3_1855785_ChIP-Seq_MESCs_Mouse0.75990135
84SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.74071942
85TP63_17297297_ChIP-ChIP_HaCaT_Human0.73917039
86* AUTS2_25519132_ChIP-Seq_293T-REX_Human0.72638471
87AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.66946282
88RARA_24833708_ChIP-Seq_LIVER_Mouse0.66782481
89IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.65846163
90* RAD21_21589869_ChIP-Seq_MESCs_Mouse0.64145693
91Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.63737307
92* ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.63290799
93ESR1_21235772_ChIP-Seq_MCF-7_Human0.63058417
94* PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.62413577
95RARB_24833708_ChIP-Seq_LIVER_Mouse0.61283634
96FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.60455706
97PPAR_26484153_Chip-Seq_NCI-H1993_Human0.60048609
98NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.59336851
99RACK7_27058665_Chip-Seq_MCF-7_Human0.59093091
100IRF8_22096565_ChIP-ChIP_GC-B_Human0.59024350
101* ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.58654639
102FOXO3_23340844_ChIP-Seq_DLD1_Human0.57812950
103FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.56630585
104RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.55762633
105EGR1_19032775_ChIP-ChIP_M12_Human0.55750680
106NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.55150688
107CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.53148714
108SOX2_20726797_ChIP-Seq_SW620_Human0.52513835
109PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.52422554
110TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.50214668
111CEBPB_22108803_ChIP-Seq_LS180_Human0.49124037
112CDX2_20551321_ChIP-Seq_CACO-2_Human0.48695072
113PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.48315531
114CSB_26484114_Chip-Seq_FIBROBLAST_Human0.47570322
115AR_20517297_ChIP-Seq_VCAP_Human0.47549103
116FOXA1_25552417_ChIP-Seq_VCAP_Human0.47023681
117FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.46459347
118GATA6_25053715_ChIP-Seq_YYC3_Human0.46190240
119FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.46084440
120SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.45963496
121ATF3_27146783_Chip-Seq_COLON_Human0.45852051
122* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.44652519
123TBX20_22080862_ChIP-Seq_HEART_Mouse0.44074013
124TBX20_22328084_ChIP-Seq_HEART_Mouse0.44074013
125BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.43863753
126STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.43795341
127GATA1_19941826_ChIP-Seq_K562_Human0.43435687
128MYC_19915707_ChIP-ChIP_AK7_Human0.42859343
129BRD4_27068464_Chip-Seq_AML-cells_Mouse0.41579991
130SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.41577193
131KAP1_22055183_ChIP-Seq_ESCs_Mouse0.41393919
132* CBP_21632823_ChIP-Seq_H3396_Human0.41070658
133P53_21459846_ChIP-Seq_SAOS-2_Human0.40320182
134SMC3_22415368_ChIP-Seq_MEFs_Mouse0.40165780
135GATA3_24758297_ChIP-Seq_MCF-7_Human0.39902843
136NFIB_24661679_ChIP-Seq_LUNG_Mouse0.39897148
137CJUN_26792858_Chip-Seq_BT549_Human0.39610951
138ERG_21242973_ChIP-ChIP_JURKAT_Human0.39609397
139GATA2_19941826_ChIP-Seq_K562_Human0.39545270
140P63_26484246_Chip-Seq_KERATINOCYTES_Human0.38852972

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system8.10825320
2MP0005360_urolithiasis7.26994345
3MP0005085_abnormal_gallbladder_physiolo6.00805632
4MP0005365_abnormal_bile_salt5.78338397
5MP0008875_abnormal_xenobiotic_pharmacok4.64459649
6MP0003806_abnormal_nucleotide_metabolis3.98732932
7MP0003252_abnormal_bile_duct3.84015838
8MP0010329_abnormal_lipoprotein_level3.37981885
9MP0009840_abnormal_foam_cell3.30980368
10MP0005083_abnormal_biliary_tract2.90420490
11MP0003195_calcinosis2.84422403
12MP0005332_abnormal_amino_acid2.70112333
13MP0001666_abnormal_nutrient_absorption2.40065485
14MP0003191_abnormal_cellular_cholesterol2.10019799
15MP0003705_abnormal_hypodermis_morpholog2.08682388
16MP0000609_abnormal_liver_physiology2.07562645
17MP0002118_abnormal_lipid_homeostasis1.97984608
18MP0005058_abnormal_lysosome_morphology1.96895361
19MP0004019_abnormal_vitamin_homeostasis1.95085140
20MP0005257_abnormal_intraocular_pressure1.91603669
21MP0003868_abnormal_feces_composition1.86218847
22MP0004858_abnormal_nervous_system1.83384530
23MP0002138_abnormal_hepatobiliary_system1.79076536
24MP0001958_emphysema1.76320617
25MP0005319_abnormal_enzyme/_coenzyme1.75751777
26MP0008438_abnormal_cutaneous_collagen1.73970491
27MP0009697_abnormal_copulation1.55325889
28MP0005584_abnormal_enzyme/coenzyme_acti1.44438167
29MP0003011_delayed_dark_adaptation1.42072710
30MP0001764_abnormal_homeostasis1.38608136
31MP0006054_spinal_hemorrhage1.35581720
32MP0003656_abnormal_erythrocyte_physiolo1.33174979
33MP0003566_abnormal_cell_adhesion1.31080924
34MP0010368_abnormal_lymphatic_system1.28640811
35MP0003186_abnormal_redox_activity1.28404286
36MP0005451_abnormal_body_composition1.21876377
37MP0000598_abnormal_liver_morphology1.18742050
38MP0009643_abnormal_urine_homeostasis1.17769083
39MP0009053_abnormal_anal_canal1.09434327
40MP0003172_abnormal_lysosome_physiology1.07689381
41MP0002254_reproductive_system_inflammat1.06771402
42MP0005508_abnormal_skeleton_morphology1.06317379
43MP0009384_cardiac_valve_regurgitation1.03791610
44MP0002089_abnormal_postnatal_growth/wei1.02521084
45MP0005647_abnormal_sex_gland1.00503908
46MP0002249_abnormal_larynx_morphology0.97668194
47MP0009764_decreased_sensitivity_to0.97082218
48MP0009763_increased_sensitivity_to0.96695263
49MP0000003_abnormal_adipose_tissue0.95941744
50MP0002933_joint_inflammation0.95596543
51MP0000604_amyloidosis0.93338519
52MP0000751_myopathy0.89680849
53MP0005670_abnormal_white_adipose0.88860987
54MP0005375_adipose_tissue_phenotype0.87115272
55MP0000013_abnormal_adipose_tissue0.85696652
56MP0005220_abnormal_exocrine_pancreas0.85492524
57MP0000858_altered_metastatic_potential0.84084471
58MP0005636_abnormal_mineral_homeostasis0.82876942
59MP0005084_abnormal_gallbladder_morpholo0.82112752
60MP0001533_abnormal_skeleton_physiology0.81915728
61MP0002998_abnormal_bone_remodeling0.81791245
62MP0000678_abnormal_parathyroid_gland0.80268217
63MP0005275_abnormal_skin_tensile0.80095187
64MP0002971_abnormal_brown_adipose0.79298033
65MP0008469_abnormal_protein_level0.79128195
66MP0009642_abnormal_blood_homeostasis0.78961760
67MP0001849_ear_inflammation0.78400735
68MP0010030_abnormal_orbit_morphology0.77537262
69MP0005390_skeleton_phenotype0.77095107
70MP0005408_hypopigmentation0.75114875
71MP0005409_darkened_coat_color0.73807555
72MP0003091_abnormal_cell_migration0.73661267
73MP0005376_homeostasis/metabolism_phenot0.72389469
74MP0003950_abnormal_plasma_membrane0.71637205
75MP0002060_abnormal_skin_morphology0.71593888
76MP0009780_abnormal_chondrocyte_physiolo0.70539472
77MP0001243_abnormal_dermal_layer0.69046454
78MP0005334_abnormal_fat_pad0.68975882
79MP0003279_aneurysm0.68241226
80MP0005503_abnormal_tendon_morphology0.68179042
81MP0002078_abnormal_glucose_homeostasis0.68006686
82MP0004130_abnormal_muscle_cell0.66727723
83MP0002108_abnormal_muscle_morphology0.66311833
84MP0002132_abnormal_respiratory_system0.63910739
85MP0005023_abnormal_wound_healing0.63712136
86MP0005165_increased_susceptibility_to0.63468896
87MP0001661_extended_life_span0.62947088
88MP0000681_abnormal_thyroid_gland0.62694321
89MP0004782_abnormal_surfactant_physiolog0.62004992
90MP0003183_abnormal_peptide_metabolism0.61454968
91MP0005666_abnormal_adipose_tissue0.61293661
92MP0000566_synostosis0.60743752
93MP0003879_abnormal_hair_cell0.60611474
94MP0000163_abnormal_cartilage_morphology0.60485081
95MP0006036_abnormal_mitochondrial_physio0.60350787
96MP0000639_abnormal_adrenal_gland0.58697098
97MP0009765_abnormal_xenobiotic_induced0.58372374
98MP0001756_abnormal_urination0.55171214
99MP0003690_abnormal_glial_cell0.53930583
100MP0003329_amyloid_beta_deposits0.53925566
101MP0001542_abnormal_bone_strength0.53486966
102MP0003724_increased_susceptibility_to0.52451583
103MP0002295_abnormal_pulmonary_circulatio0.52423570
104MP0009379_abnormal_foot_pigmentation0.51732231
105MP0005248_abnormal_Harderian_gland0.50921266
106MP0005266_abnormal_metabolism0.50871611
107MP0005395_other_phenotype0.50460186
108MP0005595_abnormal_vascular_smooth0.47036226
109MP0005448_abnormal_energy_balance0.46353880
110MP0009672_abnormal_birth_weight0.45790212
111MP0004272_abnormal_basement_membrane0.45675014
112MP0002876_abnormal_thyroid_physiology0.44870297
113MP0002168_other_aberrant_phenotype0.44309386
114MP0005535_abnormal_body_temperature0.44150961
115MP0009115_abnormal_fat_cell0.43551896
116MP0002928_abnormal_bile_duct0.43129017
117MP0002136_abnormal_kidney_physiology0.42767694
118MP0000249_abnormal_blood_vessel0.42738710
119MP0005164_abnormal_response_to0.42331973
120MP0003436_decreased_susceptibility_to0.42110333
121MP0003638_abnormal_response/metabolism_0.41242867
122MP0005464_abnormal_platelet_physiology0.40057657
123MP0003075_altered_response_to0.39211520
124MP0008873_increased_physiological_sensi0.38812771
125MP0002970_abnormal_white_adipose0.37158186
126MP0004883_abnormal_blood_vessel0.37134674
127MP0002796_impaired_skin_barrier0.36623695
128MP0002282_abnormal_trachea_morphology0.36553694
129MP0002837_dystrophic_cardiac_calcinosis0.36241980
130MP0000579_abnormal_nail_morphology0.34094350
131MP0002896_abnormal_bone_mineralization0.33714554
132MP0001915_intracranial_hemorrhage0.33660856
133MP0005166_decreased_susceptibility_to0.33284750
134MP0000767_abnormal_smooth_muscle0.33211566
135MP0001853_heart_inflammation0.32676191

Predicted human phenotypes

RankGene SetZ-score
1Deep venous thrombosis (HP:0002625)7.28635169
2Abnormality of aromatic amino acid family metabolism (HP:0004338)7.05194384
3Intrahepatic cholestasis (HP:0001406)6.96592416
4Xanthomatosis (HP:0000991)6.42139308
5Abnormality of monocarboxylic acid metabolism (HP:0010996)6.37116839
6Prolonged partial thromboplastin time (HP:0003645)6.11997381
7Hypobetalipoproteinemia (HP:0003563)5.95299483
8Hyperlipoproteinemia (HP:0010980)5.32073749
9Complement deficiency (HP:0004431)5.14491174
10Hypolipoproteinemia (HP:0010981)4.76278101
11Hypoalphalipoproteinemia (HP:0003233)4.45283926
12Joint hemorrhage (HP:0005261)4.42524756
13Hyperammonemia (HP:0001987)4.39369948
14Abnormality of the level of lipoprotein cholesterol (HP:0010979)4.29729683
15Abnormality of the common coagulation pathway (HP:0010990)4.28336614
16Epidermoid cyst (HP:0200040)4.20283214
17Hyperglycinemia (HP:0002154)4.19859942
18Abnormality of glutamine family amino acid metabolism (HP:0010902)4.17243144
19Ketosis (HP:0001946)4.10467736
20Abnormality of methionine metabolism (HP:0010901)4.04881726
21Abnormality of complement system (HP:0005339)4.04829458
22Abnormality of sulfur amino acid metabolism (HP:0004339)4.04449944
23Abnormality of aspartate family amino acid metabolism (HP:0010899)3.91342567
24Abnormality of glycine metabolism (HP:0010895)3.82705032
25Abnormality of serine family amino acid metabolism (HP:0010894)3.82705032
26Fat malabsorption (HP:0002630)3.82543782
27Hyperglycinuria (HP:0003108)3.77477132
28Hypoglycemic coma (HP:0001325)3.76566880
29Abnormality of the intrinsic pathway (HP:0010989)3.71972721
30Vertebral compression fractures (HP:0002953)3.60361852
31Abnormality of pyrimidine metabolism (HP:0004353)3.50171968
32Myocardial infarction (HP:0001658)3.41942617
33Hypercholesterolemia (HP:0003124)3.38446937
34Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.23117224
35Conjugated hyperbilirubinemia (HP:0002908)3.19762566
36Abnormality of fatty-acid metabolism (HP:0004359)3.18990480
37Hyperbilirubinemia (HP:0002904)3.13438839
38Cervical subluxation (HP:0003308)3.04586848
39Hepatocellular carcinoma (HP:0001402)2.98397239
40Delayed CNS myelination (HP:0002188)2.98146490
41Abnormality of serum amino acid levels (HP:0003112)2.92983729
42Ketoacidosis (HP:0001993)2.91941233
43Skin nodule (HP:0200036)2.87344683
44Steatorrhea (HP:0002570)2.84627972
45Abnormality of nucleobase metabolism (HP:0010932)2.81783981
46Spontaneous abortion (HP:0005268)2.70395173
47Aortic dissection (HP:0002647)2.68419595
48Aortic aneurysm (HP:0004942)2.68291620
49Vascular calcification (HP:0004934)2.66605265
50Ankle contracture (HP:0006466)2.65208202
51Vascular tortuosity (HP:0004948)2.63306679
52Mitral stenosis (HP:0001718)2.61242319
53Nephritis (HP:0000123)2.59995120
54Cardiovascular calcification (HP:0011915)2.56670563
55Systemic lupus erythematosus (HP:0002725)2.53266655
56Abnormality of carpal bone ossification (HP:0006257)2.51273986
57Cerebral aneurysm (HP:0004944)2.51157876
58Blue sclerae (HP:0000592)2.51009661
59Metabolic acidosis (HP:0001942)2.49975362
60Abnormality of purine metabolism (HP:0004352)2.47589988
61Hypochromic microcytic anemia (HP:0004840)2.47050732
62Protrusio acetabuli (HP:0003179)2.46546010
63Urinary glycosaminoglycan excretion (HP:0003541)2.46444333
64Mucopolysacchariduria (HP:0008155)2.46444333
65Abnormality of dicarboxylic acid metabolism (HP:0010995)2.44181440
66Dicarboxylic aciduria (HP:0003215)2.44181440
67Abnormality of mucopolysaccharide metabolism (HP:0011020)2.42070024
68Abnormality of polysaccharide metabolism (HP:0011012)2.42070024
69Abnormality of glycosaminoglycan metabolism (HP:0004371)2.42070024
70Abnormal gallbladder morphology (HP:0012437)2.36239438
71Lethargy (HP:0001254)2.36211961
72Hypoglycemic seizures (HP:0002173)2.35063102
73Neonatal short-limb short stature (HP:0008921)2.34807887
74Spastic diplegia (HP:0001264)2.33384166
75Abnormal delivery (HP:0001787)2.31687983
76Cholelithiasis (HP:0001081)2.30732928
77Follicular hyperkeratosis (HP:0007502)2.29878316
78Wormian bones (HP:0002645)2.29866231
79Abnormality of the acetabulum (HP:0003170)2.29388158
80Amyloidosis (HP:0011034)2.27488924
81Acanthocytosis (HP:0001927)2.26888644
82Peritonitis (HP:0002586)2.26339726
83Arterial tortuosity (HP:0005116)2.24417367
84Soft skin (HP:0000977)2.22846478
85Achilles tendon contracture (HP:0001771)2.22586265
86Premature rupture of membranes (HP:0001788)2.21958027
87Coxa vara (HP:0002812)2.21904804
88Purpura (HP:0000979)2.21770801
89Glomerulonephritis (HP:0000099)2.21577118
90Broad metatarsal (HP:0001783)2.21062503
91Abnormal cartilage morphology (HP:0002763)2.20840328
92Dysostosis multiplex (HP:0000943)2.20391153
93Late onset (HP:0003584)2.20092233
94Neonatal onset (HP:0003623)2.19902166
95Cholecystitis (HP:0001082)2.19158459
96Abnormal gallbladder physiology (HP:0012438)2.19158459
97Fragile skin (HP:0001030)2.18455315
98Malnutrition (HP:0004395)2.17711514
99Menorrhagia (HP:0000132)2.17188745
100Spinal rigidity (HP:0003306)2.16910751
101Abnormality of proline metabolism (HP:0010907)2.15925617
102Hydroxyprolinuria (HP:0003080)2.15925617
103Joint stiffness (HP:0001387)2.15059915
104Gout (HP:0001997)2.15021359
105Polycythemia (HP:0001901)2.14906113
106Bladder diverticulum (HP:0000015)2.13293641
107Abnormality of the Achilles tendon (HP:0005109)2.13244013
108Enlarged kidneys (HP:0000105)2.11902321
109Irritability (HP:0000737)2.09681341
110Shallow orbits (HP:0000586)2.08802976
111Esophageal varix (HP:0002040)2.08328667
112Cerebral edema (HP:0002181)2.07622992
113Flat acetabular roof (HP:0003180)2.05906081
114Gingival bleeding (HP:0000225)2.04327631
115Pancreatitis (HP:0001733)2.02928079
116Back pain (HP:0003418)2.02888450
117Ulnar bowing (HP:0003031)2.02340312
118Aneurysm (HP:0002617)2.02265138
119Nonimmune hydrops fetalis (HP:0001790)2.01661519
120Opisthotonus (HP:0002179)2.01063101
121Sensorimotor neuropathy (HP:0007141)1.99084333
122Abnormal ossification of hand bones (HP:0005921)1.97419320
123Hypophosphatemic rickets (HP:0004912)1.95138894
124Increased variability in muscle fiber diameter (HP:0003557)1.95128124
125Abnormality of the gallbladder (HP:0005264)1.92657089
126Thrombophlebitis (HP:0004418)1.92452058
127Distal upper limb amyotrophy (HP:0007149)1.92317451
128Upper limb amyotrophy (HP:0009129)1.92317451
129Abnormality of iron homeostasis (HP:0011031)1.92059194
130Abnormality of dentin (HP:0010299)1.91037025
131Hemorrhage of the eye (HP:0011885)1.90778842
132Type 1 muscle fiber predominance (HP:0003803)1.89357235
133Hypertriglyceridemia (HP:0002155)1.88988941
134Recurrent gram-negative bacterial infections (HP:0005420)1.88827594
135Hyperinsulinemic hypoglycemia (HP:0000825)1.88237395
136Brushfield spots (HP:0001088)1.87858898
137Vomiting (HP:0002013)1.87703533
138J-shaped sella turcica (HP:0002680)1.87698510
139Rickets (HP:0002748)1.86433962
140Increased connective tissue (HP:0009025)1.85816913
141Abnormality of transition element cation homeostasis (HP:0011030)1.85790632
142Ovoid vertebral bodies (HP:0003300)1.85680176
143Biconcave vertebral bodies (HP:0004586)1.84029917
144Elbow flexion contracture (HP:0002987)1.83262103
145Generalized aminoaciduria (HP:0002909)1.82849492
146Hyperglycemia (HP:0003074)1.82253701
147Atrophic scars (HP:0001075)1.82157985
148Poikilocytosis (HP:0004447)1.82018290
149Mildly elevated creatine phosphokinase (HP:0008180)1.81185901
150Ectopia lentis (HP:0001083)1.79447669
151Dilatation of the ascending aorta (HP:0005111)1.79269956
152Slender build (HP:0001533)1.78478702
153Wrist flexion contracture (HP:0001239)1.77260637
154Abnormal hand bone ossification (HP:0010660)1.76138081
155Thin bony cortex (HP:0002753)1.72906776
156Abnormal tarsal ossification (HP:0008369)1.71729662
157Ileus (HP:0002595)1.70814139
158Stridor (HP:0010307)1.70785340

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK6.40010497
2ERN14.79942298
3SIK14.52512379
4TRIB33.80819418
5FGFR43.77251979
6PKN23.27954033
7ERBB42.42823128
8EPHA22.36584888
9MYLK2.22188359
10LMTK22.15571189
11TAOK32.13808851
12INSRR2.13557206
13FLT32.13160682
14LATS12.11337322
15NEK92.10059778
16MST1R1.92661164
17PTK61.75365677
18MAPK111.69215164
19PRPF4B1.65199658
20PIK3CG1.63373801
21ABL21.55173489
22PAK41.47458502
23MAP2K41.46356724
24PRKD21.37154860
25CDC42BPA1.33889674
26MAP3K101.32203388
27AKT31.32136300
28KDR1.30899868
29NTRK11.30445563
30PDGFRA1.30282361
31DDR21.26768929
32STK38L1.25058073
33MET1.24394148
34TYK21.20685770
35PIM21.20624124
36LATS21.20476056
37TESK11.18120839
38MAP3K31.17002744
39SMG11.12916645
40FRK1.12264001
41MAP2K31.11662550
42TBK11.10600937
43EEF2K1.10158955
44MAP3K61.04376312
45PRKAA21.02588288
46PTK21.01957609
47ZAP701.00981997
48ERBB20.99930160
49EPHB10.96485111
50BMX0.96097675
51DYRK1B0.95822243
52CDK60.94053650
53MAPK40.91703347
54PDGFRB0.91084563
55MAPKAPK30.90696196
56MAP3K70.89729701
57JAK20.89654683
58MAP3K110.88880595
59FGFR20.88036831
60ARAF0.87548870
61EPHA30.87114522
62EPHB20.85751615
63MOS0.84097674
64NME20.83592705
65STK380.82606411
66CSK0.82321830
67RIPK10.80056372
68KIT0.79279591
69TGFBR20.74822263
70JAK10.72558312
71MAPK120.71900186
72FER0.71707493
73ILK0.71453570
74TTN0.70396914
75WNK40.69716454
76JAK30.67742641
77MAP3K10.66186170
78PRKD30.64771018
79GRK60.63775280
80GRK50.62553341
81DAPK20.61708257
82TAOK20.61252615
83CAMK1D0.60642005
84PRKCZ0.60592651
85RPS6KA20.59502933
86LIMK10.59468830
87GSK3A0.59015419
88TESK20.58130848
89EIF2AK10.57544155
90PAK20.57461818
91MAP3K20.55798690
92IRAK30.55798086
93MTOR0.55095838
94PRKACG0.54711140
95TIE10.54581944
96MAP3K130.53288829
97STK30.53127126
98RET0.51796375
99RPS6KC10.51507595
100RPS6KL10.51507595
101MAP2K10.51409228
102PDK10.50484811
103KSR20.48399614
104ADRBK10.46389023
105CAMK2G0.45053829
106SRC0.43496294
107PDPK10.42839709
108PINK10.42183154
109MAPK150.42051108
110IGF1R0.41805745
111CDK80.41779421
112MAPK70.41734983
113CDK40.41465340
114MAP3K50.41349675
115PRKAA10.41143258
116LRRK20.40871129
117PDK20.40408321
118PTK2B0.38613048
119RPS6KA60.37638623
120FGFR30.37197874
121DAPK30.37094044
122PIK3CA0.36998245
123MAP3K140.36138314
124FGFR10.36032321
125ROCK10.35730843
126IRAK20.34754347
127PAK30.33947091
128RPS6KA40.33446855
129PBK0.33265589
130ICK0.33107277
131TRPM70.32538139
132PRKG20.31381384
133EGFR0.30955308
134TLK10.30197154
135CSF1R0.29021446
136MAP2K20.28531553
137ABL10.26790372
138PRKD10.24989970
139MAP3K80.24176723
140PRKCQ0.22276631
141SGK30.21710683
142MAP2K60.20670450
143INSR0.19075788

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001204.45660987
2Nitrogen metabolism_Homo sapiens_hsa009103.67334459
3Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.36359969
4Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.27285875
5Arginine biosynthesis_Homo sapiens_hsa002203.03672433
6Complement and coagulation cascades_Homo sapiens_hsa046102.78823938
7Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.65208785
8Tryptophan metabolism_Homo sapiens_hsa003802.64705079
9Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.64006298
10Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.58865757
11Fatty acid degradation_Homo sapiens_hsa000712.57217243
12Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.39081214
13Pentose and glucuronate interconversions_Homo sapiens_hsa000402.27787667
14Butanoate metabolism_Homo sapiens_hsa006502.05900670
15Peroxisome_Homo sapiens_hsa041462.04627961
16Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.04564924
17PPAR signaling pathway_Homo sapiens_hsa033201.92788907
18Chemical carcinogenesis_Homo sapiens_hsa052041.90866714
19Propanoate metabolism_Homo sapiens_hsa006401.88785008
20Steroid hormone biosynthesis_Homo sapiens_hsa001401.88014850
21Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.86502331
22Fatty acid metabolism_Homo sapiens_hsa012121.85262659
23Histidine metabolism_Homo sapiens_hsa003401.81709549
24Other glycan degradation_Homo sapiens_hsa005111.69733900
25Drug metabolism - other enzymes_Homo sapiens_hsa009831.69590285
26Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.67441001
27Caffeine metabolism_Homo sapiens_hsa002321.64435083
28Staphylococcus aureus infection_Homo sapiens_hsa051501.64107385
29beta-Alanine metabolism_Homo sapiens_hsa004101.63916821
30Selenocompound metabolism_Homo sapiens_hsa004501.62975190
31Retinol metabolism_Homo sapiens_hsa008301.62825011
32Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.56512682
33Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.54115065
34Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.54040844
352-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.51941271
36Phenylalanine metabolism_Homo sapiens_hsa003601.50094095
37Bile secretion_Homo sapiens_hsa049761.46122494
38Sulfur metabolism_Homo sapiens_hsa009201.44827551
39Tyrosine metabolism_Homo sapiens_hsa003501.38767967
40Pyruvate metabolism_Homo sapiens_hsa006201.34547935
41Starch and sucrose metabolism_Homo sapiens_hsa005001.33456048
42Cysteine and methionine metabolism_Homo sapiens_hsa002701.29982349
43Folate biosynthesis_Homo sapiens_hsa007901.27287992
44Fatty acid elongation_Homo sapiens_hsa000621.24836075
45Biosynthesis of amino acids_Homo sapiens_hsa012301.24186217
46Steroid biosynthesis_Homo sapiens_hsa001001.22225868
47Sulfur relay system_Homo sapiens_hsa041221.17831849
48Carbon metabolism_Homo sapiens_hsa012001.15859090
49Fat digestion and absorption_Homo sapiens_hsa049751.14720884
50ABC transporters_Homo sapiens_hsa020101.06863871
51Cyanoamino acid metabolism_Homo sapiens_hsa004601.06569322
52Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.04934200
53Arginine and proline metabolism_Homo sapiens_hsa003301.04446522
54One carbon pool by folate_Homo sapiens_hsa006700.96863539
55Maturity onset diabetes of the young_Homo sapiens_hsa049500.92537510
56Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.92224169
57Vitamin B6 metabolism_Homo sapiens_hsa007500.90701856
58Lysine degradation_Homo sapiens_hsa003100.86722939
59Vitamin digestion and absorption_Homo sapiens_hsa049770.84425347
60Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.82621952
61Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.82478498
62Pertussis_Homo sapiens_hsa051330.81273182
63Mineral absorption_Homo sapiens_hsa049780.74015906
64Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.73184931
65Glutathione metabolism_Homo sapiens_hsa004800.70112005
66Glycerolipid metabolism_Homo sapiens_hsa005610.63004064
67Fatty acid biosynthesis_Homo sapiens_hsa000610.60970430
68Pentose phosphate pathway_Homo sapiens_hsa000300.59393828
69Focal adhesion_Homo sapiens_hsa045100.55478692
70Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.49486448
71Metabolic pathways_Homo sapiens_hsa011000.44117233
72N-Glycan biosynthesis_Homo sapiens_hsa005100.42705315
73Lysosome_Homo sapiens_hsa041420.39511282
74Prion diseases_Homo sapiens_hsa050200.36900770
75Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.35379996
76Sphingolipid metabolism_Homo sapiens_hsa006000.33978872
77Galactose metabolism_Homo sapiens_hsa000520.33706320
78Adipocytokine signaling pathway_Homo sapiens_hsa049200.27535743
79Insulin resistance_Homo sapiens_hsa049310.26920672
80Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.25701240
81Fructose and mannose metabolism_Homo sapiens_hsa000510.22676123
82alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.18955277
83Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.17704641
84African trypanosomiasis_Homo sapiens_hsa051430.17620443
85AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.15376896
86PI3K-Akt signaling pathway_Homo sapiens_hsa041510.14646401
87Proteoglycans in cancer_Homo sapiens_hsa052050.14431489
88Linoleic acid metabolism_Homo sapiens_hsa005910.13025249
89Glucagon signaling pathway_Homo sapiens_hsa049220.09205585
90AMPK signaling pathway_Homo sapiens_hsa041520.07854411
91Glycerophospholipid metabolism_Homo sapiens_hsa005640.06129850
92Bladder cancer_Homo sapiens_hsa052190.04628965
93Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.02887692
94Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.02321532
95Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.00211585
96Longevity regulating pathway - mammal_Homo sapiens_hsa04211-0.2122431
97Thyroid hormone synthesis_Homo sapiens_hsa04918-0.1852611
98Hepatitis C_Homo sapiens_hsa05160-0.1793145
99Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604-0.1547091
100Arachidonic acid metabolism_Homo sapiens_hsa00590-0.1314838
101Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532-0.1285155
102Renin-angiotensin system_Homo sapiens_hsa04614-0.1263302
103Systemic lupus erythematosus_Homo sapiens_hsa05322-0.1251620
104Malaria_Homo sapiens_hsa05144-0.0883224
105Insulin signaling pathway_Homo sapiens_hsa04910-0.0701125
106Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932-0.0679368
107Amoebiasis_Homo sapiens_hsa05146-0.0679023
108Ovarian steroidogenesis_Homo sapiens_hsa04913-0.0646087
109Central carbon metabolism in cancer_Homo sapiens_hsa05230-0.0445370
110Glycosaminoglycan degradation_Homo sapiens_hsa00531-0.0415192
111ECM-receptor interaction_Homo sapiens_hsa04512-0.0281418
112Protein digestion and absorption_Homo sapiens_hsa04974-0.0201848

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