

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | * type I interferon signaling pathway (GO:0060337) | 6.01387357 |
| 2 | * cellular response to type I interferon (GO:0071357) | 6.01387357 |
| 3 | * response to type I interferon (GO:0034340) | 5.93325104 |
| 4 | regulation of vitamin D biosynthetic process (GO:0060556) | 5.16210424 |
| 5 | regulation of interferon-alpha production (GO:0032647) | 5.09763205 |
| 6 | regulation of chronic inflammatory response (GO:0002676) | 5.07948168 |
| 7 | regulation of T-helper 1 cell differentiation (GO:0045625) | 5.00297191 |
| 8 | cellular response to interferon-alpha (GO:0035457) | 4.81543261 |
| 9 | * negative regulation of viral genome replication (GO:0045071) | 4.74852252 |
| 10 | negative regulation of interleukin-12 production (GO:0032695) | 4.72503300 |
| 11 | positive regulation of interferon-alpha production (GO:0032727) | 4.48281301 |
| 12 | response to interferon-alpha (GO:0035455) | 4.45888306 |
| 13 | response to peptidoglycan (GO:0032494) | 4.45345746 |
| 14 | regulation of cytokine secretion involved in immune response (GO:0002739) | 4.20111173 |
| 15 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 4.18392294 |
| 16 | regulation of vitamin metabolic process (GO:0030656) | 4.10570809 |
| 17 | positive regulation of type 2 immune response (GO:0002830) | 3.94165054 |
| 18 | positive regulation of chemokine biosynthetic process (GO:0045080) | 3.92882155 |
| 19 | positive regulation of heat generation (GO:0031652) | 3.89341097 |
| 20 | negative regulation of cytokine production involved in immune response (GO:0002719) | 3.84852493 |
| 21 | macrophage activation involved in immune response (GO:0002281) | 3.84009089 |
| 22 | NIK/NF-kappaB signaling (GO:0038061) | 3.81419670 |
| 23 | regulation of fever generation (GO:0031620) | 3.78159457 |
| 24 | regulation of chemokine biosynthetic process (GO:0045073) | 3.78023977 |
| 25 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 3.73110981 |
| 26 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.70781026 |
| 27 | * interferon-gamma-mediated signaling pathway (GO:0060333) | 3.67444331 |
| 28 | response to interferon-beta (GO:0035456) | 3.61895078 |
| 29 | immunoglobulin mediated immune response (GO:0016064) | 3.58834082 |
| 30 | myeloid dendritic cell differentiation (GO:0043011) | 3.54476123 |
| 31 | positive regulation of interferon-beta production (GO:0032728) | 3.53539262 |
| 32 | defense response to protozoan (GO:0042832) | 3.53462518 |
| 33 | cellular response to exogenous dsRNA (GO:0071360) | 3.53242867 |
| 34 | branching involved in labyrinthine layer morphogenesis (GO:0060670) | 3.50500915 |
| 35 | regulation of podosome assembly (GO:0071801) | 3.49605328 |
| 36 | cellular response to virus (GO:0098586) | 3.49470279 |
| 37 | regulation of type 2 immune response (GO:0002828) | 3.45525560 |
| 38 | response to protozoan (GO:0001562) | 3.41167622 |
| 39 | positive regulation of defense response to virus by host (GO:0002230) | 3.41064418 |
| 40 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.39182126 |
| 41 | regulation of RIG-I signaling pathway (GO:0039535) | 3.37894662 |
| 42 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.36338476 |
| 43 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.30214200 |
| 44 | germinal center formation (GO:0002467) | 3.29318791 |
| 45 | positive regulation of NF-kappaB import into nucleus (GO:0042346) | 3.28913273 |
| 46 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.26647356 |
| 47 | * negative regulation of viral process (GO:0048525) | 3.26383265 |
| 48 | negative regulation of cell killing (GO:0031342) | 3.26142324 |
| 49 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.26142324 |
| 50 | modulation by symbiont of host defense response (GO:0052031) | 3.25023879 |
| 51 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 3.25023879 |
| 52 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 3.25023879 |
| 53 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 3.25023879 |
| 54 | modulation by symbiont of host immune response (GO:0052553) | 3.25023879 |
| 55 | positive regulation by symbiont of host defense response (GO:0052509) | 3.25023879 |
| 56 | * regulation of viral genome replication (GO:0045069) | 3.21442067 |
| 57 | T cell migration (GO:0072678) | 3.21013160 |
| 58 | * defense response to virus (GO:0051607) | 3.19819122 |
| 59 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.19763989 |
| 60 | regulation of mononuclear cell migration (GO:0071675) | 3.18174129 |
| 61 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.16123061 |
| 62 | cellular response to interferon-beta (GO:0035458) | 3.14317314 |
| 63 | regulation of interleukin-12 production (GO:0032655) | 3.11886848 |
| 64 | negative regulation of type I interferon production (GO:0032480) | 3.11156825 |
| 65 | granulocyte activation (GO:0036230) | 3.10555305 |
| 66 | negative regulation of T cell mediated immunity (GO:0002710) | 3.08707109 |
| 67 | lymphocyte chemotaxis (GO:0048247) | 3.08435215 |
| 68 | negative regulation of production of molecular mediator of immune response (GO:0002701) | 3.07644349 |
| 69 | neutrophil activation involved in immune response (GO:0002283) | 3.07594125 |
| 70 | regulation of immunoglobulin secretion (GO:0051023) | 3.07370046 |
| 71 | positive regulation of acute inflammatory response (GO:0002675) | 3.07183352 |
| 72 | regulation of T-helper cell differentiation (GO:0045622) | 3.06478037 |
| 73 | positive regulation of nitric oxide biosynthetic process (GO:0045429) | 3.06318071 |
| 74 | T-helper 1 type immune response (GO:0042088) | 3.04477921 |
| 75 | myeloid dendritic cell activation (GO:0001773) | 3.04273895 |
| 76 | regulation of membrane protein ectodomain proteolysis (GO:0051043) | 3.03964510 |
| 77 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 3.03908526 |
| 78 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.02332641 |
| 79 | negative regulation of myeloid cell apoptotic process (GO:0033033) | 3.01798981 |
| 80 | detection of other organism (GO:0098543) | 3.00553540 |
| 81 | * cellular response to interferon-gamma (GO:0071346) | 3.00083032 |
| 82 | regulation of interleukin-8 biosynthetic process (GO:0045414) | 2.99785789 |
| 83 | regulation of nitric oxide biosynthetic process (GO:0045428) | 2.99510849 |
| 84 | positive regulation of heterotypic cell-cell adhesion (GO:0034116) | 2.98829724 |
| 85 | negative regulation of toll-like receptor 4 signaling pathway (GO:0034144) | 2.97756803 |
| 86 | regulation of T cell tolerance induction (GO:0002664) | 2.97530081 |
| 87 | cellular response to lipopolysaccharide (GO:0071222) | 2.97027900 |
| 88 | positive regulation of membrane protein ectodomain proteolysis (GO:0051044) | 2.95630121 |
| 89 | positive regulation of interleukin-6 production (GO:0032755) | 2.94051002 |
| 90 | antigen processing and presentation of endogenous antigen (GO:0019883) | 2.93648913 |
| 91 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 2.91574541 |
| 92 | cellular response to molecule of bacterial origin (GO:0071219) | 2.90922822 |
| 93 | regulation of defense response to virus by host (GO:0050691) | 2.89399832 |
| 94 | regulation of heat generation (GO:0031650) | 2.89224634 |
| 95 | * response to interferon-gamma (GO:0034341) | 2.89009146 |
| 96 | interferon-gamma secretion (GO:0072643) | 2.88792614 |
| 97 | negative regulation of nitric oxide biosynthetic process (GO:0045019) | 2.88627549 |
| 98 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 2.87659301 |
| 99 | negative regulation of type 2 immune response (GO:0002829) | 2.87346499 |
| 100 | regulation of antigen processing and presentation (GO:0002577) | 2.86184075 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 7.81384601 |
| 2 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 5.76865565 |
| 3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 5.45027864 |
| 4 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.67386533 |
| 5 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 4.20570050 |
| 6 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 3.90958785 |
| 7 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.61151467 |
| 8 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.52915517 |
| 9 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.31595620 |
| 10 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.04361629 |
| 11 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 3.01103718 |
| 12 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.97399703 |
| 13 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.91733360 |
| 14 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.87143305 |
| 15 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.83386106 |
| 16 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.81295875 |
| 17 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.62795407 |
| 18 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.39524676 |
| 19 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.19397714 |
| 20 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.09507541 |
| 21 | GATA1_22025678_ChIP-Seq_K562_Human | 2.03058227 |
| 22 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 2.01666224 |
| 23 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.01569106 |
| 24 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.91525045 |
| 25 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.75774628 |
| 26 | MYB_26560356_Chip-Seq_TH2_Human | 1.73330815 |
| 27 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.71698971 |
| 28 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.68391496 |
| 29 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.68191292 |
| 30 | * MAF_26560356_Chip-Seq_TH1_Human | 1.67694529 |
| 31 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.66766599 |
| 32 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.65207280 |
| 33 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.61420810 |
| 34 | SPI1_23127762_ChIP-Seq_K562_Human | 1.57995214 |
| 35 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.48592632 |
| 36 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.47638829 |
| 37 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.46384112 |
| 38 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.39000872 |
| 39 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.37062986 |
| 40 | MYB_26560356_Chip-Seq_TH1_Human | 1.36764945 |
| 41 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.36481297 |
| 42 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.31043109 |
| 43 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.30494347 |
| 44 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.30256783 |
| 45 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.29547754 |
| 46 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.24882637 |
| 47 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.24627411 |
| 48 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.24594839 |
| 49 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.23018843 |
| 50 | UTX_26944678_Chip-Seq_JUKART_Human | 1.20851711 |
| 51 | GATA3_26560356_Chip-Seq_TH2_Human | 1.20224507 |
| 52 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.19432614 |
| 53 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.18750176 |
| 54 | MAF_26560356_Chip-Seq_TH2_Human | 1.18416508 |
| 55 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.16600584 |
| 56 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.16475056 |
| 57 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.15403369 |
| 58 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.15344765 |
| 59 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.14183194 |
| 60 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.14149235 |
| 61 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.13781459 |
| 62 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.12637253 |
| 63 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.11527364 |
| 64 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.11176204 |
| 65 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.10025666 |
| 66 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.09861072 |
| 67 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.08041819 |
| 68 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.07566971 |
| 69 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.00901178 |
| 70 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.00144190 |
| 71 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.00014397 |
| 72 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.99902735 |
| 73 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.99732716 |
| 74 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.97354276 |
| 75 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.97116630 |
| 76 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.96878999 |
| 77 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.94563338 |
| 78 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.94098626 |
| 79 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 0.93341060 |
| 80 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.92988379 |
| 81 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.91696111 |
| 82 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.90683941 |
| 83 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 0.88412554 |
| 84 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.87893763 |
| 85 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 0.87457816 |
| 86 | GATA1_19941826_ChIP-Seq_K562_Human | 0.85689804 |
| 87 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.80222199 |
| 88 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 0.77758884 |
| 89 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.75570978 |
| 90 | * SOX2_20726797_ChIP-Seq_SW620_Human | 0.75382966 |
| 91 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 0.75280125 |
| 92 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.75071706 |
| 93 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 0.74904679 |
| 94 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.74904679 |
| 95 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 0.74904679 |
| 96 | * ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 0.74360422 |
| 97 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.73765079 |
| 98 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.72098329 |
| 99 | * STAT1_20625510_ChIP-Seq_HELA_Human | 0.71605694 |
| 100 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.69845698 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003303_peritoneal_inflammation | 5.57673396 |
| 2 | MP0003724_increased_susceptibility_to | 4.24588921 |
| 3 | MP0006082_CNS_inflammation | 4.07896487 |
| 4 | MP0009785_altered_susceptibility_to | 3.84698737 |
| 5 | MP0003436_decreased_susceptibility_to | 3.65652668 |
| 6 | MP0001835_abnormal_antigen_presentation | 3.50863319 |
| 7 | MP0002148_abnormal_hypersensitivity_rea | 3.45446570 |
| 8 | MP0004510_myositis | 3.05351257 |
| 9 | MP0005671_abnormal_response_to | 2.95978254 |
| 10 | MP0005000_abnormal_immune_tolerance | 2.94032505 |
| 11 | MP0005387_immune_system_phenotype | 2.82676651 |
| 12 | MP0001790_abnormal_immune_system | 2.82676651 |
| 13 | MP0005025_abnormal_response_to | 2.76983416 |
| 14 | MP0003300_gastrointestinal_ulcer | 2.52602861 |
| 15 | MP0002419_abnormal_innate_immunity | 2.50825528 |
| 16 | MP0001800_abnormal_humoral_immune | 2.40825735 |
| 17 | MP0002723_abnormal_immune_serum | 2.38367796 |
| 18 | MP0009764_decreased_sensitivity_to | 2.34723860 |
| 19 | MP0002452_abnormal_antigen_presenting | 2.26677521 |
| 20 | MP0004947_skin_inflammation | 2.26392491 |
| 21 | MP0001533_abnormal_skeleton_physiology | 2.14342537 |
| 22 | MP0005058_abnormal_lysosome_morphology | 2.09011632 |
| 23 | MP0002139_abnormal_hepatobiliary_system | 2.01786129 |
| 24 | MP0005451_abnormal_body_composition | 2.00459261 |
| 25 | MP0008004_abnormal_stomach_pH | 1.98750273 |
| 26 | MP0010155_abnormal_intestine_physiology | 1.98485203 |
| 27 | MP0003075_altered_response_to | 1.97346095 |
| 28 | MP0001819_abnormal_immune_cell | 1.93275712 |
| 29 | MP0002420_abnormal_adaptive_immunity | 1.92564157 |
| 30 | MP0002332_abnormal_exercise_endurance | 1.85621399 |
| 31 | MP0000685_abnormal_immune_system | 1.84739413 |
| 32 | MP0001845_abnormal_inflammatory_respons | 1.84552534 |
| 33 | MP0008469_abnormal_protein_level | 1.75789487 |
| 34 | MP0001853_heart_inflammation | 1.74370883 |
| 35 | MP0009333_abnormal_splenocyte_physiolog | 1.70742064 |
| 36 | MP0009840_abnormal_foam_cell | 1.68012131 |
| 37 | MP0003195_calcinosis | 1.63996571 |
| 38 | MP0000343_altered_response_to | 1.58423117 |
| 39 | MP0002405_respiratory_system_inflammati | 1.57227552 |
| 40 | MP0003453_abnormal_keratinocyte_physiol | 1.55801456 |
| 41 | MP0009278_abnormal_bone_marrow | 1.53205916 |
| 42 | MP0003448_altered_tumor_morphology | 1.49953467 |
| 43 | MP0003806_abnormal_nucleotide_metabolis | 1.45405345 |
| 44 | MP0002254_reproductive_system_inflammat | 1.43971579 |
| 45 | MP0000716_abnormal_immune_system | 1.41506277 |
| 46 | MP0006054_spinal_hemorrhage | 1.38224648 |
| 47 | MP0005310_abnormal_salivary_gland | 1.36390319 |
| 48 | MP0005166_decreased_susceptibility_to | 1.34227802 |
| 49 | MP0003191_abnormal_cellular_cholesterol | 1.33578993 |
| 50 | MP0001545_abnormal_hematopoietic_system | 1.31753224 |
| 51 | MP0005397_hematopoietic_system_phenotyp | 1.31753224 |
| 52 | MP0003763_abnormal_thymus_physiology | 1.27974613 |
| 53 | MP0002398_abnormal_bone_marrow | 1.26159666 |
| 54 | MP0000858_altered_metastatic_potential | 1.26016522 |
| 55 | MP0005167_abnormal_blood-brain_barrier | 1.21125428 |
| 56 | MP0003690_abnormal_glial_cell | 1.20229617 |
| 57 | MP0009763_increased_sensitivity_to | 1.16950362 |
| 58 | MP0002998_abnormal_bone_remodeling | 1.15124032 |
| 59 | MP0003172_abnormal_lysosome_physiology | 1.12338139 |
| 60 | MP0005164_abnormal_response_to | 1.11090181 |
| 61 | MP0005464_abnormal_platelet_physiology | 1.10931446 |
| 62 | MP0000604_amyloidosis | 1.08679288 |
| 63 | MP0003656_abnormal_erythrocyte_physiolo | 1.07952283 |
| 64 | MP0002429_abnormal_blood_cell | 1.06613500 |
| 65 | MP0002138_abnormal_hepatobiliary_system | 1.03789385 |
| 66 | MP0000689_abnormal_spleen_morphology | 1.01171817 |
| 67 | MP0002722_abnormal_immune_system | 0.99431334 |
| 68 | MP0009765_abnormal_xenobiotic_induced | 0.90355553 |
| 69 | MP0001501_abnormal_sleep_pattern | 0.89715163 |
| 70 | MP0005390_skeleton_phenotype | 0.88622399 |
| 71 | MP0003091_abnormal_cell_migration | 0.86560552 |
| 72 | MP0001542_abnormal_bone_strength | 0.86414681 |
| 73 | MP0005165_increased_susceptibility_to | 0.84565151 |
| 74 | MP0004883_abnormal_blood_vessel | 0.77710047 |
| 75 | MP0001663_abnormal_digestive_system | 0.77312947 |
| 76 | MP0003646_muscle_fatigue | 0.75909964 |
| 77 | MP0002933_joint_inflammation | 0.74992937 |
| 78 | MP0005666_abnormal_adipose_tissue | 0.73993127 |
| 79 | MP0005023_abnormal_wound_healing | 0.73881519 |
| 80 | MP0008874_decreased_physiological_sensi | 0.71760198 |
| 81 | MP0002277_abnormal_respiratory_mucosa | 0.71300994 |
| 82 | MP0001873_stomach_inflammation | 0.70898903 |
| 83 | MP0003045_fibrosis | 0.70487789 |
| 84 | MP0005535_abnormal_body_temperature | 0.68428951 |
| 85 | MP0000920_abnormal_myelination | 0.68280989 |
| 86 | MP0004808_abnormal_hematopoietic_stem | 0.66073257 |
| 87 | MP0008260_abnormal_autophagy | 0.63912810 |
| 88 | MP0005266_abnormal_metabolism | 0.63362919 |
| 89 | MP0003183_abnormal_peptide_metabolism | 0.62049752 |
| 90 | MP0002877_abnormal_melanocyte_morpholog | 0.61927493 |
| 91 | MP0003221_abnormal_cardiomyocyte_apopto | 0.59198458 |
| 92 | MP0001851_eye_inflammation | 0.58535945 |
| 93 | MP0000249_abnormal_blood_vessel | 0.58219378 |
| 94 | MP0000465_gastrointestinal_hemorrhage | 0.55958484 |
| 95 | MP0000609_abnormal_liver_physiology | 0.55945981 |
| 96 | MP0005647_abnormal_sex_gland | 0.55788812 |
| 97 | MP0005319_abnormal_enzyme/_coenzyme | 0.54680574 |
| 98 | MP0003866_abnormal_defecation | 0.53619286 |
| 99 | MP0010352_gastrointestinal_tract_polyps | 0.53106267 |
| 100 | MP0000703_abnormal_thymus_morphology | 0.52411511 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Optic neuritis (HP:0100653) | 6.30588268 |
| 2 | Retrobulbar optic neuritis (HP:0100654) | 6.30588268 |
| 3 | Orchitis (HP:0100796) | 6.15905398 |
| 4 | Myositis (HP:0100614) | 5.58635920 |
| 5 | Abnormality of liposaccharide metabolism (HP:0010968) | 5.21660220 |
| 6 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 5.21660220 |
| 7 | Abnormality of glycolipid metabolism (HP:0010969) | 5.21660220 |
| 8 | Stomatitis (HP:0010280) | 4.98506551 |
| 9 | Abnormality of macrophages (HP:0004311) | 4.88394144 |
| 10 | Recurrent bacterial skin infections (HP:0005406) | 4.72660716 |
| 11 | Keratoconjunctivitis sicca (HP:0001097) | 4.46134353 |
| 12 | Eczematoid dermatitis (HP:0000976) | 4.42504736 |
| 13 | Recurrent abscess formation (HP:0002722) | 4.26120526 |
| 14 | Keratoconjunctivitis (HP:0001096) | 4.09988169 |
| 15 | Mediastinal lymphadenopathy (HP:0100721) | 3.98708868 |
| 16 | Systemic lupus erythematosus (HP:0002725) | 3.93486287 |
| 17 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.88602736 |
| 18 | Increased IgM level (HP:0003496) | 3.80042480 |
| 19 | Loss of speech (HP:0002371) | 3.73587768 |
| 20 | Autoimmune thrombocytopenia (HP:0001973) | 3.67200465 |
| 21 | Vacuolated lymphocytes (HP:0001922) | 3.58572956 |
| 22 | Gangrene (HP:0100758) | 3.52212365 |
| 23 | Vasculitis (HP:0002633) | 3.51043365 |
| 24 | Pulmonary infiltrates (HP:0002113) | 3.50495935 |
| 25 | Autoimmune hemolytic anemia (HP:0001890) | 3.37577726 |
| 26 | T lymphocytopenia (HP:0005403) | 3.29660880 |
| 27 | Disinhibition (HP:0000734) | 3.28038458 |
| 28 | Parakeratosis (HP:0001036) | 3.25303019 |
| 29 | Dysostosis multiplex (HP:0000943) | 3.24721119 |
| 30 | Abnormality of T cell number (HP:0011839) | 3.22170016 |
| 31 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.17833443 |
| 32 | Recurrent viral infections (HP:0004429) | 3.14935639 |
| 33 | Increased cerebral lipofuscin (HP:0011813) | 3.11139672 |
| 34 | Encephalitis (HP:0002383) | 3.04345999 |
| 35 | Hypergammaglobulinemia (HP:0010702) | 3.00705679 |
| 36 | Hemoptysis (HP:0002105) | 3.00283210 |
| 37 | Recurrent fungal infections (HP:0002841) | 2.97845057 |
| 38 | Increased IgE level (HP:0003212) | 2.92709673 |
| 39 | Arterial thrombosis (HP:0004420) | 2.92030796 |
| 40 | Interstitial pulmonary disease (HP:0006530) | 2.86103189 |
| 41 | Recurrent skin infections (HP:0001581) | 2.84924433 |
| 42 | Increased serum ferritin (HP:0003281) | 2.76837604 |
| 43 | Meningitis (HP:0001287) | 2.72564673 |
| 44 | Anorexia (HP:0002039) | 2.71264907 |
| 45 | Gastrointestinal infarctions (HP:0005244) | 2.64912264 |
| 46 | Joint swelling (HP:0001386) | 2.63810162 |
| 47 | Nuclear cataract (HP:0100018) | 2.63166449 |
| 48 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.60287160 |
| 49 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.60287160 |
| 50 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.60287160 |
| 51 | Abnormality of the pleura (HP:0002103) | 2.59476421 |
| 52 | Obstructive lung disease (HP:0006536) | 2.57385428 |
| 53 | Chronic obstructive pulmonary disease (HP:0006510) | 2.57385428 |
| 54 | Abnormality of the pericardium (HP:0001697) | 2.56198687 |
| 55 | Amyloidosis (HP:0011034) | 2.52706931 |
| 56 | Mutism (HP:0002300) | 2.51905019 |
| 57 | Gingivitis (HP:0000230) | 2.51691494 |
| 58 | Basal ganglia calcification (HP:0002135) | 2.48610219 |
| 59 | Polyneuropathy (HP:0001271) | 2.48355587 |
| 60 | Hematochezia (HP:0002573) | 2.45150640 |
| 61 | Urticaria (HP:0001025) | 2.40447794 |
| 62 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.40208090 |
| 63 | Leukocytosis (HP:0001974) | 2.39708924 |
| 64 | Mucopolysacchariduria (HP:0008155) | 2.39461481 |
| 65 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.39461481 |
| 66 | Progressive neurologic deterioration (HP:0002344) | 2.37017959 |
| 67 | Pulmonary embolism (HP:0002204) | 2.36087490 |
| 68 | Episodic fever (HP:0001954) | 2.33138078 |
| 69 | Keratitis (HP:0000491) | 2.32072916 |
| 70 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.31353998 |
| 71 | Acne (HP:0001061) | 2.27054458 |
| 72 | Purpura (HP:0000979) | 2.26821230 |
| 73 | Abnormality of iron homeostasis (HP:0011031) | 2.25058413 |
| 74 | Neurofibrillary tangles (HP:0002185) | 2.24167262 |
| 75 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.23671135 |
| 76 | Glomerulonephritis (HP:0000099) | 2.19612117 |
| 77 | Glomerulopathy (HP:0100820) | 2.18234192 |
| 78 | Vertigo (HP:0002321) | 2.16933927 |
| 79 | Abnormality of B cell number (HP:0010975) | 2.13729050 |
| 80 | Abnormality of the endocardium (HP:0004306) | 2.11494468 |
| 81 | Chronic otitis media (HP:0000389) | 2.11207685 |
| 82 | Hepatosplenomegaly (HP:0001433) | 2.10394497 |
| 83 | Recurrent bronchitis (HP:0002837) | 2.09409392 |
| 84 | Recurrent cutaneous fungal infections (HP:0011370) | 2.07123286 |
| 85 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.07123286 |
| 86 | Petechiae (HP:0000967) | 2.06792007 |
| 87 | Nausea (HP:0002018) | 2.04934060 |
| 88 | Abnormality of T cells (HP:0002843) | 2.03223619 |
| 89 | Axonal loss (HP:0003447) | 2.02881035 |
| 90 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.02585140 |
| 91 | Arthralgia (HP:0002829) | 2.02146294 |
| 92 | Eosinophilia (HP:0001880) | 2.02101760 |
| 93 | Pustule (HP:0200039) | 1.97651022 |
| 94 | Memory impairment (HP:0002354) | 1.95821586 |
| 95 | B lymphocytopenia (HP:0010976) | 1.94442785 |
| 96 | Apathy (HP:0000741) | 1.93545671 |
| 97 | Nasal polyposis (HP:0100582) | 1.93256407 |
| 98 | Peritonitis (HP:0002586) | 1.89346958 |
| 99 | Granulocytopenia (HP:0001913) | 1.88457392 |
| 100 | Diminished motivation (HP:0000745) | 1.84932767 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRAK3 | 4.86332441 |
| 2 | GRK7 | 3.25982529 |
| 3 | MAP3K14 | 3.25179259 |
| 4 | TYK2 | 3.17406104 |
| 5 | IKBKE | 3.16633156 |
| 6 | TBK1 | 3.13804746 |
| 7 | RIPK1 | 3.04131424 |
| 8 | IRAK4 | 3.00739402 |
| 9 | TAOK2 | 2.80847929 |
| 10 | TXK | 2.51273391 |
| 11 | MAP4K1 | 2.50859743 |
| 12 | NME2 | 2.39458315 |
| 13 | RIPK4 | 2.38777210 |
| 14 | BLK | 2.24080946 |
| 15 | IKBKB | 2.23749555 |
| 16 | MAP3K3 | 2.17879967 |
| 17 | MATK | 2.15636906 |
| 18 | PRPF4B | 2.15016819 |
| 19 | JAK3 | 2.09902950 |
| 20 | DDR2 | 2.08033246 |
| 21 | BMPR2 | 2.05617721 |
| 22 | MAP3K11 | 2.05432931 |
| 23 | JAK1 | 1.98649862 |
| 24 | CSK | 1.92655439 |
| 25 | TAOK1 | 1.90967806 |
| 26 | PIM2 | 1.87902856 |
| 27 | MOS | 1.77514908 |
| 28 | MAP2K3 | 1.58949219 |
| 29 | ERN1 | 1.57172693 |
| 30 | IRAK1 | 1.55830795 |
| 31 | FGR | 1.45345246 |
| 32 | IRAK2 | 1.37434907 |
| 33 | ZAP70 | 1.32280932 |
| 34 | CHUK | 1.28708469 |
| 35 | ADRBK2 | 1.26500323 |
| 36 | TGFBR2 | 1.20118107 |
| 37 | JAK2 | 1.15552825 |
| 38 | STK10 | 1.07367698 |
| 39 | CDC42BPA | 1.04936135 |
| 40 | FGFR4 | 1.03290568 |
| 41 | LYN | 1.02907056 |
| 42 | MAP3K1 | 1.02287293 |
| 43 | SYK | 0.99503086 |
| 44 | MAP3K13 | 0.97731807 |
| 45 | LCK | 0.96156421 |
| 46 | TESK2 | 0.90922239 |
| 47 | MAP3K5 | 0.89349539 |
| 48 | EPHB1 | 0.86740183 |
| 49 | BTK | 0.82288888 |
| 50 | KIT | 0.80173700 |
| 51 | HCK | 0.79755153 |
| 52 | CLK1 | 0.79279611 |
| 53 | HIPK2 | 0.77966664 |
| 54 | EPHA3 | 0.74913144 |
| 55 | SIK3 | 0.73027034 |
| 56 | ACVR1B | 0.71631800 |
| 57 | PIM1 | 0.68176928 |
| 58 | MARK3 | 0.67941293 |
| 59 | MAP2K6 | 0.67526153 |
| 60 | FES | 0.66471505 |
| 61 | CSF1R | 0.62702255 |
| 62 | ABL2 | 0.62377797 |
| 63 | TYRO3 | 0.59791920 |
| 64 | TNK2 | 0.58781417 |
| 65 | ARAF | 0.56789949 |
| 66 | FGFR3 | 0.54391616 |
| 67 | BMX | 0.51372932 |
| 68 | LATS2 | 0.51130823 |
| 69 | DYRK3 | 0.51125347 |
| 70 | TAOK3 | 0.50828205 |
| 71 | PKN1 | 0.46747339 |
| 72 | ITK | 0.46369240 |
| 73 | EIF2AK2 | 0.40033909 |
| 74 | MAPK4 | 0.36253934 |
| 75 | PDK1 | 0.36236952 |
| 76 | DAPK2 | 0.34674157 |
| 77 | TESK1 | 0.34543850 |
| 78 | CAMKK2 | 0.28801054 |
| 79 | MAPK7 | 0.28270373 |
| 80 | EGFR | 0.27824144 |
| 81 | ABL1 | 0.27316909 |
| 82 | FYN | 0.27092133 |
| 83 | CDK6 | 0.26987213 |
| 84 | INSR | 0.25257548 |
| 85 | STK24 | 0.24230370 |
| 86 | TEC | 0.24167306 |
| 87 | MAPK11 | 0.23615908 |
| 88 | MAPKAPK2 | 0.23269564 |
| 89 | DYRK1B | 0.22576902 |
| 90 | PDPK1 | 0.22335198 |
| 91 | PRKCQ | 0.22280292 |
| 92 | PRKCD | 0.21782624 |
| 93 | PDGFRB | 0.20750776 |
| 94 | PAK4 | 0.18921528 |
| 95 | PDGFRA | 0.16287565 |
| 96 | MAP3K6 | 0.15547784 |
| 97 | TRIB3 | 0.14946334 |
| 98 | MST4 | 0.14629477 |
| 99 | CDK4 | 0.14628329 |
| 100 | SIK2 | 0.11446520 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 3.29883339 |
| 2 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 3.21581266 |
| 3 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.88970614 |
| 4 | Allograft rejection_Homo sapiens_hsa05330 | 2.82624375 |
| 5 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.80878412 |
| 6 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.62818548 |
| 7 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 2.62297107 |
| 8 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.61859992 |
| 9 | Leishmaniasis_Homo sapiens_hsa05140 | 2.49404378 |
| 10 | Malaria_Homo sapiens_hsa05144 | 2.47222399 |
| 11 | TNF signaling pathway_Homo sapiens_hsa04668 | 2.40571341 |
| 12 | African trypanosomiasis_Homo sapiens_hsa05143 | 2.35268349 |
| 13 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 2.35116319 |
| 14 | Asthma_Homo sapiens_hsa05310 | 2.29748932 |
| 15 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.27058466 |
| 16 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.24142702 |
| 17 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.23728177 |
| 18 | Influenza A_Homo sapiens_hsa05164 | 2.20693197 |
| 19 | Measles_Homo sapiens_hsa05162 | 2.18041278 |
| 20 | Legionellosis_Homo sapiens_hsa05134 | 2.12783290 |
| 21 | Pertussis_Homo sapiens_hsa05133 | 2.05373618 |
| 22 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.95807760 |
| 23 | Tuberculosis_Homo sapiens_hsa05152 | 1.89157902 |
| 24 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.84095631 |
| 25 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.83673437 |
| 26 | Other glycan degradation_Homo sapiens_hsa00511 | 1.79690321 |
| 27 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.77202472 |
| 28 | Hepatitis C_Homo sapiens_hsa05160 | 1.70785125 |
| 29 | Salmonella infection_Homo sapiens_hsa05132 | 1.68747680 |
| 30 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.66508641 |
| 31 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.57249907 |
| 32 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.55042655 |
| 33 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.54685076 |
| 34 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.53785725 |
| 35 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.51256448 |
| 36 | Lysosome_Homo sapiens_hsa04142 | 1.42454388 |
| 37 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.37035609 |
| 38 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.25064762 |
| 39 | Hepatitis B_Homo sapiens_hsa05161 | 1.24670853 |
| 40 | Viral myocarditis_Homo sapiens_hsa05416 | 1.18815833 |
| 41 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.12664895 |
| 42 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.11753199 |
| 43 | Prion diseases_Homo sapiens_hsa05020 | 1.11246562 |
| 44 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.08386389 |
| 45 | Shigellosis_Homo sapiens_hsa05131 | 1.04518491 |
| 46 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.99363378 |
| 47 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.97635750 |
| 48 | Apoptosis_Homo sapiens_hsa04210 | 0.95308112 |
| 49 | Phagosome_Homo sapiens_hsa04145 | 0.91536172 |
| 50 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.85931842 |
| 51 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.81548218 |
| 52 | Amoebiasis_Homo sapiens_hsa05146 | 0.80568699 |
| 53 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.78696090 |
| 54 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.77986745 |
| 55 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.77102578 |
| 56 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.75898409 |
| 57 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.74837470 |
| 58 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.74315212 |
| 59 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.72940672 |
| 60 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.65787393 |
| 61 | Bladder cancer_Homo sapiens_hsa05219 | 0.65368735 |
| 62 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.59119715 |
| 63 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.58172204 |
| 64 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.56247229 |
| 65 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.52514472 |
| 66 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.44345219 |
| 67 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.44201229 |
| 68 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.43757456 |
| 69 | HTLV-I infection_Homo sapiens_hsa05166 | 0.40572409 |
| 70 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.38437074 |
| 71 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.37964543 |
| 72 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.37915439 |
| 73 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.30744467 |
| 74 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.30509931 |
| 75 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.29943455 |
| 76 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.29139365 |
| 77 | Insulin resistance_Homo sapiens_hsa04931 | 0.26393344 |
| 78 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.26081915 |
| 79 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.25450979 |
| 80 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.25202627 |
| 81 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.24637367 |
| 82 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.24502215 |
| 83 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.24272664 |
| 84 | Endocytosis_Homo sapiens_hsa04144 | 0.23354648 |
| 85 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.23200750 |
| 86 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.21218552 |
| 87 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.20084103 |
| 88 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.18076916 |
| 89 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.18007474 |
| 90 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.17919382 |
| 91 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.15151068 |
| 92 | Galactose metabolism_Homo sapiens_hsa00052 | 0.14823316 |
| 93 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.14768918 |
| 94 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.10174908 |
| 95 | Platelet activation_Homo sapiens_hsa04611 | 0.08222645 |
| 96 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.07933016 |
| 97 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.07736138 |
| 98 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.07427556 |
| 99 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.06454718 |
| 100 | Mineral absorption_Homo sapiens_hsa04978 | 0.05798709 |

