OBP2B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein localization to cilium (GO:0061512)7.99425264
2cardiac right ventricle morphogenesis (GO:0003215)6.85427544
3regulation of female gonad development (GO:2000194)6.74021072
4one-carbon compound transport (GO:0019755)6.33700804
5endothelial cell chemotaxis (GO:0035767)5.85456712
6ethanol oxidation (GO:0006069)5.80530860
7fibroblast migration (GO:0010761)5.74257239
8positive regulation of male gonad development (GO:2000020)5.43818205
9regulation of cholesterol biosynthetic process (GO:0045540)5.40164491
10atrioventricular valve morphogenesis (GO:0003181)5.16285159
11negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)5.00430584
12regulation of cell proliferation involved in kidney development (GO:1901722)4.98483187
13cellular response to gonadotropin stimulus (GO:0071371)4.97199506
14cellular glucuronidation (GO:0052695)4.88058751
15glucuronate metabolic process (GO:0019585)4.85062062
16uronic acid metabolic process (GO:0006063)4.85062062
17positive regulation of digestive system process (GO:0060456)4.75229683
18calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)4.69630754
19positive regulation of metanephros development (GO:0072216)4.66901876
20epoxygenase P450 pathway (GO:0019373)4.66555463
21activation of protein kinase A activity (GO:0034199)4.61449709
22metanephric mesenchyme development (GO:0072075)4.60102375
23antibacterial humoral response (GO:0019731)4.54469748
24negative regulation of smooth muscle cell differentiation (GO:0051151)4.52376885
25adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)4.51494370
26glomerular basement membrane development (GO:0032836)4.49864998
27ethanol metabolic process (GO:0006067)4.44184129
28regulation of male gonad development (GO:2000018)4.42539976
29cornea development in camera-type eye (GO:0061303)4.33289333
30heart valve morphogenesis (GO:0003179)4.30101381
31antimicrobial humoral response (GO:0019730)4.20532176
32notochord development (GO:0030903)4.19820505
33kidney mesenchyme development (GO:0072074)4.19584353
34activation of Rac GTPase activity (GO:0032863)4.14067248
35parturition (GO:0007567)4.13215584
36regulation of sodium ion transmembrane transport (GO:1902305)4.11885775
37flavonoid metabolic process (GO:0009812)4.11851590
38positive regulation of odontogenesis (GO:0042482)4.10281972
39gas transport (GO:0015669)4.09447020
40tachykinin receptor signaling pathway (GO:0007217)4.09181201
41establishment of apical/basal cell polarity (GO:0035089)4.07123582
42negative regulation of macroautophagy (GO:0016242)4.06825802
43regulation of gonadotropin secretion (GO:0032276)3.98177538
44exogenous drug catabolic process (GO:0042738)3.94557662
45lateral ventricle development (GO:0021670)3.92632113
46negative regulation of metanephros development (GO:0072217)3.90517627
47regulation of glomerulus development (GO:0090192)3.88715169
48diaphragm development (GO:0060539)3.78219814
49regulation of sodium ion transmembrane transporter activity (GO:2000649)3.74798688
50renal absorption (GO:0070293)3.70376085
51branching involved in prostate gland morphogenesis (GO:0060442)3.66577464
52sex determination (GO:0007530)3.61051982
53mating behavior (GO:0007617)3.59348000
54face development (GO:0060324)3.57957786
55hemidesmosome assembly (GO:0031581)3.57948806
56water-soluble vitamin biosynthetic process (GO:0042364)3.54722041
57alkaloid metabolic process (GO:0009820)3.54045234
58post-embryonic morphogenesis (GO:0009886)3.52903049
59negative regulation of mesenchymal cell apoptotic process (GO:2001054)3.52573448
60regulation of cholesterol metabolic process (GO:0090181)3.51138986
61cell morphogenesis involved in neuron differentiation (GO:0048667)3.49909983
62negative regulation of cytosolic calcium ion concentration (GO:0051481)3.49348825
63molting cycle (GO:0042303)3.47486447
64hair cycle (GO:0042633)3.47486447
65basic amino acid transport (GO:0015802)3.42496221
66amyloid precursor protein catabolic process (GO:0042987)3.42152502
67response to gonadotropin (GO:0034698)3.41771674
68positive regulation of p38MAPK cascade (GO:1900745)3.40849328
69bundle of His cell to Purkinje myocyte communication (GO:0086069)3.40254173
70positive regulation of hormone biosynthetic process (GO:0046886)3.39051326
71membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.38291463
72protein insertion into membrane (GO:0051205)3.37738250
73negative regulation of astrocyte differentiation (GO:0048712)3.37072046
74regulation of sodium ion transport (GO:0002028)3.36913608
75cAMP biosynthetic process (GO:0006171)3.36424622
76cellular potassium ion homeostasis (GO:0030007)3.35941387
77hormone catabolic process (GO:0042447)3.35183194
78membrane repolarization during cardiac muscle cell action potential (GO:0086013)3.33303616
79establishment of skin barrier (GO:0061436)3.33011911
80GDP-mannose metabolic process (GO:0019673)3.32964900
81drug catabolic process (GO:0042737)3.32710998
82endocardial cushion development (GO:0003197)3.32245869
83glomerulus development (GO:0032835)3.31233767
84regulation of cardioblast differentiation (GO:0051890)3.31022947
85skeletal muscle organ development (GO:0060538)3.30931396
86metanephric epithelium development (GO:0072207)3.29295270
87water transport (GO:0006833)3.29214277
88omega-hydroxylase P450 pathway (GO:0097267)3.26450800
89establishment of monopolar cell polarity (GO:0061162)3.26433894
90establishment or maintenance of monopolar cell polarity (GO:0061339)3.26433894
91G-protein coupled receptor internalization (GO:0002031)3.26213805
92Notch signaling involved in heart development (GO:0061314)3.26057900
93camera-type eye morphogenesis (GO:0048593)3.25269661
94cellular response to ATP (GO:0071318)3.21546577
95regulation of heart rate by cardiac conduction (GO:0086091)3.19057477
96epithelial cell differentiation involved in kidney development (GO:0035850)3.17532196
97negative regulation of kidney development (GO:0090185)3.17142694
98tight junction assembly (GO:0070830)3.15837916
99layer formation in cerebral cortex (GO:0021819)3.15785611
100cardiac ventricle morphogenesis (GO:0003208)3.15114814
101amyloid precursor protein metabolic process (GO:0042982)3.13101179
102negative regulation of lipase activity (GO:0060192)3.12941089
103mesonephros development (GO:0001823)3.09477785
104muscle cell fate commitment (GO:0042693)3.09360704
105negative regulation of microtubule polymerization (GO:0031115)3.08504934
106regulation of water loss via skin (GO:0033561)3.07352955
107mRNA cleavage (GO:0006379)3.07220172
108regulation of sarcomere organization (GO:0060297)3.06550750
109macroautophagy (GO:0016236)3.06492579
110male sex determination (GO:0030238)3.05587794
111regulation of metanephros development (GO:0072215)3.04378093
112pseudouridine synthesis (GO:0001522)3.03916413
113negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)3.02980198
114relaxation of cardiac muscle (GO:0055119)3.02772869
115outer ear morphogenesis (GO:0042473)3.00545497
116response to follicle-stimulating hormone (GO:0032354)2.99433589
117desmosome organization (GO:0002934)2.99207711
118regulation of mesenchymal cell apoptotic process (GO:2001053)2.99023634
119nephron tubule formation (GO:0072079)2.98713780
120epithelial cell fate commitment (GO:0072148)2.98094468
121cellular response to follicle-stimulating hormone stimulus (GO:0071372)2.97715749
122negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)2.94249829
123mRNA polyadenylation (GO:0006378)2.94147537
124histone mRNA catabolic process (GO:0071044)2.91814697
125positive regulation of mesonephros development (GO:0061213)2.91668819
126ovulation cycle (GO:0042698)2.90646926
127membrane repolarization during action potential (GO:0086011)2.90091550
128mesenchymal to epithelial transition (GO:0060231)2.89395102
129response to vitamin A (GO:0033189)2.89119989
130cardiac chamber morphogenesis (GO:0003206)2.88981297
131cardiac conduction (GO:0061337)2.86828603
132regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:00033392.86615295
133toxin metabolic process (GO:0009404)2.86143769
134negative regulation of autophagy (GO:0010507)2.86051088
135fluid transport (GO:0042044)2.85574518
136eyelid development in camera-type eye (GO:0061029)2.84324994
137sodium ion export (GO:0071436)2.84192118
138positive regulation of cell size (GO:0045793)2.82061611
139dopamine receptor signaling pathway (GO:0007212)2.81170687
140cytokine biosynthetic process (GO:0042089)2.80650121
141negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.80033359
142chemical homeostasis within a tissue (GO:0048875)2.80000224
143regulation of steroid hormone biosynthetic process (GO:0090030)2.79886714
144protein localization to endosome (GO:0036010)2.79174969
145positive regulation of steroid biosynthetic process (GO:0010893)2.78716090
146vitamin transmembrane transport (GO:0035461)2.76508198
147potassium ion homeostasis (GO:0055075)2.76502317
148mammary gland development (GO:0030879)2.75989472
149negative regulation of T cell receptor signaling pathway (GO:0050860)2.75941164
150negative regulation of dendrite morphogenesis (GO:0050774)2.75494199
151negative regulation of sodium ion transport (GO:0010766)2.74949337
152cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.74201109
153L-ascorbic acid metabolic process (GO:0019852)2.73847387
154negative regulation of DNA-templated transcription, elongation (GO:0032785)2.72856637
155sulfur amino acid catabolic process (GO:0000098)2.70799378
156regulation of p38MAPK cascade (GO:1900744)2.70727475
157regulation of mesonephros development (GO:0061217)2.70398698
158cardiac epithelial to mesenchymal transition (GO:0060317)2.69921188
159keratinocyte development (GO:0003334)2.69198472
160seminiferous tubule development (GO:0072520)2.65880353
161primary alcohol catabolic process (GO:0034310)2.64841829
162peptide biosynthetic process (GO:0043043)2.62565952
163cellular copper ion homeostasis (GO:0006878)2.62159742
164regulation of receptor binding (GO:1900120)2.61822893
165inner cell mass cell proliferation (GO:0001833)2.61060816
166axonal fasciculation (GO:0007413)2.59329395
167cell communication involved in cardiac conduction (GO:0086065)2.58675616
168regulation of secondary heart field cardioblast proliferation (GO:0003266)2.56459482
169regulation of cardioblast proliferation (GO:0003264)2.56459482
170positive regulation of hormone metabolic process (GO:0032352)2.55438442
171glutamate secretion (GO:0014047)2.54319607
172calcium-mediated signaling using intracellular calcium source (GO:0035584)2.53860783
173cellular response to glucagon stimulus (GO:0071377)2.52690708
174neuron cell-cell adhesion (GO:0007158)2.52642052
175response to caffeine (GO:0031000)2.49806899
176cytoskeletal anchoring at plasma membrane (GO:0007016)2.47562024
177carnitine metabolic process (GO:0009437)2.46635463
178endoplasmic reticulum calcium ion homeostasis (GO:0032469)2.44625020
179semaphorin-plexin signaling pathway (GO:0071526)2.41968595
180positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.40415551
181ectoderm development (GO:0007398)2.39074678
182short-chain fatty acid metabolic process (GO:0046459)2.35938944
183positive regulation of steroid metabolic process (GO:0045940)2.32692694
184positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.32246076
185cAMP metabolic process (GO:0046058)2.31859486
186cilium morphogenesis (GO:0060271)2.31158280
187forebrain neuron development (GO:0021884)2.29923373
188apoptotic cell clearance (GO:0043277)2.29434483
189behavioral response to cocaine (GO:0048148)2.27520396
190CDP-diacylglycerol biosynthetic process (GO:0016024)2.25449516
191atrial cardiac muscle cell action potential (GO:0086014)2.22001855
192polyol transport (GO:0015791)2.19731753
193cellular response to electrical stimulus (GO:0071257)2.18496554
194neuron recognition (GO:0008038)2.17258348
195membrane repolarization (GO:0086009)2.17076115
196cellular response to epidermal growth factor stimulus (GO:0071364)2.16395018
197cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.16060750
198* sensory perception of smell (GO:0007608)19.6780158
199* sensory perception of chemical stimulus (GO:0007606)10.4677825

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_21235772_ChIP-Seq_MCF-7_Human3.56286192
2TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse3.40139903
3SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.33879477
4TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.33670772
5TP63_17297297_ChIP-ChIP_HaCaT_Human3.26439219
6DROSHA_22980978_ChIP-Seq_HELA_Human3.16725792
7TRIM28_21343339_ChIP-Seq_HEK293_Human2.85525015
8ZNF263_19887448_ChIP-Seq_K562_Human2.55624561
9ERG_21242973_ChIP-ChIP_JURKAT_Human2.51052474
10CHD7_19251738_ChIP-ChIP_MESCs_Mouse2.48719986
11MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.36297604
12CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human2.19109192
13CLOCK_20551151_ChIP-Seq_293T_Human2.02251196
14EZH2_22144423_ChIP-Seq_EOC_Human2.00071958
15SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.88055447
16RNF2_18974828_ChIP-Seq_MESCs_Mouse1.87130311
17EZH2_18974828_ChIP-Seq_MESCs_Mouse1.87130311
18BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.84881998
19ESR2_21235772_ChIP-Seq_MCF-7_Human1.84806737
20ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.83310700
21RXR_22108803_ChIP-Seq_LS180_Human1.81842315
22LXR_22158963_ChIP-Seq_LIVER_Mouse1.76887848
23LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.73669179
24RXR_22158963_ChIP-Seq_LIVER_Mouse1.67462324
25KDM2B_26808549_Chip-Seq_K562_Human1.64450592
26P63_26484246_Chip-Seq_KERATINOCYTES_Human1.64250661
27EED_16625203_ChIP-ChIP_MESCs_Mouse1.63890615
28IKZF1_21737484_ChIP-ChIP_HCT116_Human1.61558964
29KDM2B_26808549_Chip-Seq_SUP-B15_Human1.57037817
30SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.54491840
31ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.53258680
32MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.52465405
33SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.49439790
34TP53_20018659_ChIP-ChIP_R1E_Mouse1.49436973
35MTF2_20144788_ChIP-Seq_MESCs_Mouse1.48010720
36ZNF217_24962896_ChIP-Seq_MCF-7_Human1.47182725
37SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.46807067
38SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.46688032
39SOX2_27498859_Chip-Seq_STOMACH_Mouse1.46272171
40TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.45984140
41CREB1_26743006_Chip-Seq_LNCaP_Human1.42826408
42SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.40204547
43HIF1A_21447827_ChIP-Seq_MCF-7_Human1.37540500
44KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.37460463
45ELK3_25401928_ChIP-Seq_HUVEC_Human1.36523299
46RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.36161848
47AHR_22903824_ChIP-Seq_MCF-7_Human1.34356964
48ETV2_25802403_ChIP-Seq_MESCs_Mouse1.34051936
49SCL_19346495_ChIP-Seq_HPC-7_Human1.33169973
50TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.32065764
51UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.30958778
52FOXO3_23340844_ChIP-Seq_DLD1_Human1.30368629
53SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.30272872
54SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.30272872
55STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.28891988
56NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.28359861
57AR_21572438_ChIP-Seq_LNCaP_Human1.28310191
58YY1_22570637_ChIP-Seq_MALME-3M_Human1.28166659
59WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.27891011
60STAT6_21828071_ChIP-Seq_BEAS2B_Human1.27097010
61ZFP281_18757296_ChIP-ChIP_E14_Mouse1.25765725
62RARB_27405468_Chip-Seq_BRAIN_Mouse1.25691320
63ESR1_15608294_ChIP-ChIP_MCF-7_Human1.25248820
64VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.25194370
65SMC4_20622854_ChIP-Seq_HELA_Human1.24865364
66SA1_27219007_Chip-Seq_ERYTHROID_Human1.24443001
67NOTCH1_21737748_ChIP-Seq_TLL_Human1.24436858
68JARID2_20075857_ChIP-Seq_MESCs_Mouse1.23814232
69CBX2_27304074_Chip-Seq_ESCs_Mouse1.23557214
70SUZ12_27294783_Chip-Seq_ESCs_Mouse1.22338182
71CDX2_19796622_ChIP-Seq_MESCs_Mouse1.21788849
72FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.21703233
73JARID2_20064375_ChIP-Seq_MESCs_Mouse1.21631384
74TAF15_26573619_Chip-Seq_HEK293_Human1.21512440
75ESR1_20079471_ChIP-ChIP_T-47D_Human1.20991741
76PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.20745432
77RUNX1_27514584_Chip-Seq_MCF-7_Human1.20582935
78RARG_19884340_ChIP-ChIP_MEFs_Mouse1.20526809
79SOX9_24532713_ChIP-Seq_HFSC_Mouse1.20481318
80SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.19987548
81RING1B_27294783_Chip-Seq_NPCs_Mouse1.19536742
82CTCF_27219007_Chip-Seq_ERYTHROID_Human1.19151421
83TP63_22573176_ChIP-Seq_HFKS_Human1.18043935
84AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.17869778
85EP300_21415370_ChIP-Seq_HL-1_Mouse1.17457183
86BCL6_27268052_Chip-Seq_Bcells_Human1.16553991
87GATA3_24758297_ChIP-Seq_MCF-7_Human1.16269618
88BMI1_23680149_ChIP-Seq_NPCS_Mouse1.15991868
89P300_27058665_Chip-Seq_ZR-75-30cells_Human1.14680122
90ERG_20517297_ChIP-Seq_VCAP_Human1.14167323
91P68_20966046_ChIP-Seq_HELA_Human1.13690859
92PPARA_22158963_ChIP-Seq_LIVER_Mouse1.11966979
93LXR_22292898_ChIP-Seq_THP-1_Human1.10746074
94ARNT_22903824_ChIP-Seq_MCF-7_Human1.10713499
95GATA3_27048872_Chip-Seq_THYMUS_Human1.09651038
96WT1_25993318_ChIP-Seq_PODOCYTE_Human1.08910819
97RING1B_27294783_Chip-Seq_ESCs_Mouse1.08313223
98* JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.07523055
99GATA6_21074721_ChIP-Seq_CACO-2_Human1.06041509
100SMAD4_21741376_ChIP-Seq_HESCs_Human1.04729020
101DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.04396802
102ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.04352166
103RNF2_27304074_Chip-Seq_ESCs_Mouse1.04090823
104ISL1_27105846_Chip-Seq_CPCs_Mouse1.03518278
105SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.03250225
106STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.02677345
107BCOR_27268052_Chip-Seq_Bcells_Human1.02664185
108KDM2B_26808549_Chip-Seq_JURKAT_Human1.01864214
109EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.01179272
110OCT4_19829295_ChIP-Seq_ESCs_Human1.00460583
111RACK7_27058665_Chip-Seq_MCF-7_Human0.98693431
112ZFP281_27345836_Chip-Seq_ESCs_Mouse0.98631178
113EZH2_27294783_Chip-Seq_ESCs_Mouse0.98457716
114PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.98153483
115GATA1_22025678_ChIP-Seq_K562_Human0.97621391
116KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.97412304
117FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.97384295
118EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.97291139
119NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.97131137
120FOXA2_19822575_ChIP-Seq_HepG2_Human0.97103120
121SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.97077503
122TCF7_22412390_ChIP-Seq_EML_Mouse0.97062344
123CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.97014313
124TET1_21451524_ChIP-Seq_MESCs_Mouse0.96214155
125ATF3_27146783_Chip-Seq_COLON_Human0.94577483
126CTCF_27219007_Chip-Seq_Bcells_Human0.94144361
127CJUN_26792858_Chip-Seq_BT549_Human0.94134220
128RNF2_27304074_Chip-Seq_NSC_Mouse0.94069835
129TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.93904302
130SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.93551631
131FOXM1_26456572_ChIP-Seq_MCF-7_Human0.93497354
132ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.93417539
133RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.93024903
134MYC_19915707_ChIP-ChIP_AK7_Human0.91935330
135PIAS1_25552417_ChIP-Seq_VCAP_Human0.91660741
136VDR_24787735_ChIP-Seq_THP-1_Human0.91629459
137KDM2B_26808549_Chip-Seq_DND41_Human0.90766992
138SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.90495937
139KLF5_25053715_ChIP-Seq_YYC3_Human0.90341981
140GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.90224806
141P300_27268052_Chip-Seq_Bcells_Human0.90067282
142FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.88324752
143EZH2_27304074_Chip-Seq_ESCs_Mouse0.87907656
144RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.87773000
145THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.87761522
146ELK4_26923725_Chip-Seq_MESODERM_Mouse0.84037976
147BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.83370782
148EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.83261143
149GATA1_19941827_ChIP-Seq_MEL86_Mouse0.82937425
150GATA1_19941826_ChIP-Seq_K562_Human0.82480467
151SMAD3_21741376_ChIP-Seq_HESCs_Human0.81554784
152ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.80361587

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation6.87228069
2MP0005394_taste/olfaction_phenotype6.61972296
3MP0005499_abnormal_olfactory_system6.61972296
4MP0008875_abnormal_xenobiotic_pharmacok5.88775184
5MP0009384_cardiac_valve_regurgitation4.81443114
6MP0008789_abnormal_olfactory_epithelium4.60453459
7MP0003828_pulmonary_edema3.08254608
8MP0000579_abnormal_nail_morphology2.91856822
9MP0006138_congestive_heart_failure2.81918416
10MP0002254_reproductive_system_inflammat2.80164634
11MP0000566_synostosis2.68157696
12MP0003315_abnormal_perineum_morphology2.41153368
13MP0006276_abnormal_autonomic_nervous2.38133267
14MP0003806_abnormal_nucleotide_metabolis2.37004434
15MP0001501_abnormal_sleep_pattern2.19362498
16MP0008995_early_reproductive_senescence2.15986935
17MP0001873_stomach_inflammation2.01899496
18MP0003045_fibrosis2.00688550
19MP0001984_abnormal_olfaction13.3747250
20MP0000467_abnormal_esophagus_morphology1.98691425
21MP0003567_abnormal_fetal_cardiomyocyte1.95407890
22MP0003091_abnormal_cell_migration1.94671453
23MP0010234_abnormal_vibrissa_follicle1.94113933
24MP0001853_heart_inflammation1.86547952
25MP0002089_abnormal_postnatal_growth/wei1.78725127
26MP0000537_abnormal_urethra_morphology1.77655831
27MP0009379_abnormal_foot_pigmentation1.70927328
28MP0000678_abnormal_parathyroid_gland1.65319690
29MP0005365_abnormal_bile_salt1.60635317
30MP0004381_abnormal_hair_follicle1.59140551
31MP0000767_abnormal_smooth_muscle1.56179262
32MP0002139_abnormal_hepatobiliary_system1.56164377
33MP0010030_abnormal_orbit_morphology1.55559508
34MP0002735_abnormal_chemical_nociception1.54313965
35MP0002098_abnormal_vibrissa_morphology1.48857687
36MP0003936_abnormal_reproductive_system1.46551710
37MP0000013_abnormal_adipose_tissue1.46265360
38MP0001340_abnormal_eyelid_morphology1.43863063
39MP0010386_abnormal_urinary_bladder1.42484737
40MP0005595_abnormal_vascular_smooth1.40235885
41MP0002909_abnormal_adrenal_gland1.38689662
42MP0000639_abnormal_adrenal_gland1.38272810
43MP0002233_abnormal_nose_morphology1.37590691
44MP0004264_abnormal_extraembryonic_tissu1.37097671
45MP0003329_amyloid_beta_deposits1.27171664
46MP0003943_abnormal_hepatobiliary_system1.26699525
47MP0001485_abnormal_pinna_reflex1.25572893
48MP0000751_myopathy1.23974231
49MP0000383_abnormal_hair_follicle1.23439995
50MP0000538_abnormal_urinary_bladder1.22707031
51MP0005670_abnormal_white_adipose1.21317821
52MP0005623_abnormal_meninges_morphology1.15449857
53MP0002933_joint_inflammation1.15322976
54MP0005310_abnormal_salivary_gland1.13753425
55MP0002822_catalepsy1.12525680
56MP0000470_abnormal_stomach_morphology1.12266112
57MP0004859_abnormal_synaptic_plasticity1.10885389
58MP0003453_abnormal_keratinocyte_physiol1.09229139
59MP0001216_abnormal_epidermal_layer1.08853176
60MP0003075_altered_response_to1.08723837
61MP0002249_abnormal_larynx_morphology1.08143713
62MP0000026_abnormal_inner_ear1.07052619
63MP0009333_abnormal_splenocyte_physiolog1.06130886
64MP0001346_abnormal_lacrimal_gland1.04846853
65MP0002796_impaired_skin_barrier1.04316129
66MP0004858_abnormal_nervous_system1.04012688
67MP0002060_abnormal_skin_morphology1.03392520
68MP0005620_abnormal_muscle_contractility1.03334693
69MP0005174_abnormal_tail_pigmentation1.03065918
70MP0001765_abnormal_ion_homeostasis1.01787361
71MP0002127_abnormal_cardiovascular_syste0.99252389
72MP0003566_abnormal_cell_adhesion0.98738735
73MP0003755_abnormal_palate_morphology0.95942587
74MP0001963_abnormal_hearing_physiology0.95934534
75MP0010329_abnormal_lipoprotein_level0.95547060
76MP0002111_abnormal_tail_morphology0.95412964
77MP0002184_abnormal_innervation0.95226436
78MP0002653_abnormal_ependyma_morphology0.94756978
79MP0003123_paternal_imprinting0.93633491
80MP0002108_abnormal_muscle_morphology0.93271982
81MP0000604_amyloidosis0.92318095
82MP0002972_abnormal_cardiac_muscle0.91965495
83MP0001348_abnormal_lacrimal_gland0.89943006
84MP0003115_abnormal_respiratory_system0.89062438
85MP0003221_abnormal_cardiomyocyte_apopto0.88353580
86MP0003635_abnormal_synaptic_transmissio0.87506468
87MP0000049_abnormal_middle_ear0.85564378
88MP0002063_abnormal_learning/memory/cond0.84780101
89MP0002136_abnormal_kidney_physiology0.84604913
90MP0002168_other_aberrant_phenotype0.84296453
91MP0000427_abnormal_hair_cycle0.80713045
92MP0000367_abnormal_coat/_hair0.80382056
93MP0000432_abnormal_head_morphology0.79009865
94MP0000534_abnormal_ureter_morphology0.78476769
95MP0004043_abnormal_pH_regulation0.78362600
96MP0001727_abnormal_embryo_implantation0.77210016
97MP0002229_neurodegeneration0.77135128
98MP0004270_analgesia0.77083999
99MP0002932_abnormal_joint_morphology0.77028435
100MP0001784_abnormal_fluid_regulation0.75834028
101MP0004133_heterotaxia0.75774646
102MP0009780_abnormal_chondrocyte_physiolo0.75284927
103MP0009840_abnormal_foam_cell0.75182817
104MP0005584_abnormal_enzyme/coenzyme_acti0.74611516
105MP0001664_abnormal_digestion0.73775948
106MP0002896_abnormal_bone_mineralization0.72619835
107MP0000613_abnormal_salivary_gland0.72600848
108MP0003303_peritoneal_inflammation0.71223927
109MP0009046_muscle_twitch0.71102516
110MP0002116_abnormal_craniofacial_bone0.70247738
111MP0008569_lethality_at_weaning0.68828987
112MP0009745_abnormal_behavioral_response0.68489669
113MP0003690_abnormal_glial_cell0.67735971
114MP0005058_abnormal_lysosome_morphology0.67507237
115MP0003638_abnormal_response/metabolism_0.67382839
116MP0000465_gastrointestinal_hemorrhage0.66776141
117MP0004947_skin_inflammation0.66572872
118MP0002877_abnormal_melanocyte_morpholog0.64741287
119MP0003119_abnormal_digestive_system0.64341433
120MP0001440_abnormal_grooming_behavior0.63870293
121MP0005367_renal/urinary_system_phenotyp0.63796832
122MP0000516_abnormal_urinary_system0.63796832
123MP0002277_abnormal_respiratory_mucosa0.63145785
124MP0005187_abnormal_penis_morphology0.63124010
125MP0000377_abnormal_hair_follicle0.62691084
126MP0001299_abnormal_eye_distance/0.62137456
127MP0003633_abnormal_nervous_system0.61798045
128MP0004883_abnormal_blood_vessel0.61471988
129MP0005360_urolithiasis0.61431537
130MP0009931_abnormal_skin_appearance0.60965254
131MP0004885_abnormal_endolymph0.60351592
132MP0002882_abnormal_neuron_morphology0.59920448
133MP0003705_abnormal_hypodermis_morpholog0.58992850
134MP0002064_seizures0.58289885
135MP0002752_abnormal_somatic_nervous0.58021192
136MP0003942_abnormal_urinary_system0.57898179
137MP0006054_spinal_hemorrhage0.57847046
138MP0005266_abnormal_metabolism0.57555203
139MP0002734_abnormal_mechanical_nocicepti0.56531558
140MP0004134_abnormal_chest_morphology0.55048431
141MP0008874_decreased_physiological_sensi0.54008805
142MP0005167_abnormal_blood-brain_barrier0.53936773
143MP0000778_abnormal_nervous_system0.53124071
144MP0001849_ear_inflammation0.53026155
145MP0002272_abnormal_nervous_system0.51292710
146MP0003300_gastrointestinal_ulcer0.50660630
147MP0001486_abnormal_startle_reflex0.50026755
148MP0004085_abnormal_heartbeat0.49764109
149MP0005248_abnormal_Harderian_gland0.49230022
150MP0008961_abnormal_basal_metabolism0.47788174
151MP0005085_abnormal_gallbladder_physiolo0.46351556
152MP0003634_abnormal_glial_cell0.45696218
153MP0002557_abnormal_social/conspecific_i0.45503584
154MP0003283_abnormal_digestive_organ0.44069620
155MP0003279_aneurysm0.43898652
156MP0002837_dystrophic_cardiac_calcinosis0.43268711
157MP0001542_abnormal_bone_strength0.43257962
158MP0002572_abnormal_emotion/affect_behav0.42691164
159MP0002118_abnormal_lipid_homeostasis0.41684186
160MP0003195_calcinosis0.39387065
161MP0002295_abnormal_pulmonary_circulatio0.39158193
162MP0009643_abnormal_urine_homeostasis0.39157098
163MP0004811_abnormal_neuron_physiology0.39135173
164MP0003631_nervous_system_phenotype0.38995332
165MP0003252_abnormal_bile_duct0.38802364
166MP0000762_abnormal_tongue_morphology0.38393015
167MP0002234_abnormal_pharynx_morphology0.37535564
168MP0002282_abnormal_trachea_morphology0.37330328
169MP0000609_abnormal_liver_physiology0.37242370
170MP0002152_abnormal_brain_morphology0.36799615
171MP0005508_abnormal_skeleton_morphology0.36707438
172MP0004272_abnormal_basement_membrane0.35280895
173MP0002067_abnormal_sensory_capabilities0.35224059
174MP0005166_decreased_susceptibility_to0.34684742
175MP0008438_abnormal_cutaneous_collagen0.34633007
176MP0002090_abnormal_vision0.34547548
177MP0005275_abnormal_skin_tensile0.34008053
178MP0005410_abnormal_fertilization0.33804454
179MP0003186_abnormal_redox_activity0.33411873
180MP0005319_abnormal_enzyme/_coenzyme0.32530600
181MP0002092_abnormal_eye_morphology0.32385555
182MP0001177_atelectasis0.32230085
183MP0004019_abnormal_vitamin_homeostasis0.32192093
184MP0000920_abnormal_myelination0.32162319

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)5.52254657
2Ulnar bowing (HP:0003031)5.32413994
3Decreased circulating renin level (HP:0003351)4.85304648
4Mesangial abnormality (HP:0001966)4.68080063
5Chromsome breakage (HP:0040012)4.65459224
6Hypoplastic ischia (HP:0003175)4.56257563
7Testicular neoplasm (HP:0010788)4.48607332
8Bronchomalacia (HP:0002780)4.47186346
9Gonadal dysgenesis (HP:0000133)4.46931490
10Bifid scrotum (HP:0000048)4.46669257
11Synostosis involving the elbow (HP:0003938)4.39143699
12Humeroradial synostosis (HP:0003041)4.39143699
13Epiphyseal dysplasia (HP:0002656)4.36183022
14Anomalous pulmonary venous return (HP:0010772)4.35457300
15Atrioventricular block (HP:0001678)4.29343768
16Genetic anticipation (HP:0003743)4.11808094
17Duplicated collecting system (HP:0000081)4.11141334
18Abnormality of the renal collecting system (HP:0004742)4.09431100
19Limb dystonia (HP:0002451)4.08064166
20Palpitations (HP:0001962)4.00573626
21Aplasia/Hypoplasia of the pubic bone (HP:0009104)3.96389116
22Congenital stationary night blindness (HP:0007642)3.88414639
23Prolonged QT interval (HP:0001657)3.84038583
24Increased neuronal autofluorescent lipopigment (HP:0002074)3.82974696
25Vacuolated lymphocytes (HP:0001922)3.81524694
26Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)3.76676331
27Abnormality of the ischium (HP:0003174)3.75165908
28Abnormality of cochlea (HP:0000375)3.74860198
29Abnormality of the pulmonary veins (HP:0011718)3.71147084
30True hermaphroditism (HP:0010459)3.69994045
31Syncope (HP:0001279)3.69787755
32Abnormal biliary tract physiology (HP:0012439)3.67543128
33Bile duct proliferation (HP:0001408)3.67543128
34Abnormal sex determination (HP:0012244)3.67092373
35Sex reversal (HP:0012245)3.67092373
36Spastic paraparesis (HP:0002313)3.62385297
37Morphological abnormality of the inner ear (HP:0011390)3.54072329
38Germ cell neoplasia (HP:0100728)3.48339958
39Reticulocytopenia (HP:0001896)3.45379209
40Abnormality of dentin (HP:0010299)3.35681882
41Hypoplastic left heart (HP:0004383)3.32715904
42Glossoptosis (HP:0000162)3.31840345
43Torticollis (HP:0000473)3.24038827
44Bowed forearm bones (HP:0003956)3.19177632
45Bowing of the arm (HP:0006488)3.19177632
46Abnormality of sodium homeostasis (HP:0010931)3.17198770
47Increased cerebral lipofuscin (HP:0011813)3.15798143
48Cervical subluxation (HP:0003308)3.13535537
49Impaired smooth pursuit (HP:0007772)3.10826289
50Dysphonia (HP:0001618)3.08150637
51Choanal stenosis (HP:0000452)3.06693862
52Vaginal fistula (HP:0004320)3.00541810
53Vitreoretinal degeneration (HP:0000655)2.90020023
54Atonic seizures (HP:0010819)2.89943168
55Hyperaldosteronism (HP:0000859)2.82672630
56Male pseudohermaphroditism (HP:0000037)2.82616865
57Heart block (HP:0012722)2.81432888
58Craniofacial dystonia (HP:0012179)2.81275335
59Abnormal EKG (HP:0003115)2.77622764
60Optic nerve coloboma (HP:0000588)2.76828455
61Labial hypoplasia (HP:0000066)2.75670104
62Lip pit (HP:0100267)2.74187665
63Ureteral duplication (HP:0000073)2.73895597
64Protrusio acetabuli (HP:0003179)2.73314357
65Depressed nasal tip (HP:0000437)2.71320811
66Abnormality of renin-angiotensin system (HP:0000847)2.69209715
67Femoral bowing (HP:0002980)2.68878097
68Poikilocytosis (HP:0004447)2.67251489
69Abnormal atrioventricular conduction (HP:0005150)2.65651013
70Focal dystonia (HP:0004373)2.62607286
71Abnormality of pyrimidine metabolism (HP:0004353)2.59120024
72Flat capital femoral epiphysis (HP:0003370)2.56921271
73Neonatal short-limb short stature (HP:0008921)2.56531634
74Hypoplastic heart (HP:0001961)2.54350047
75Primary atrial arrhythmia (HP:0001692)2.54349556
76Vertebral clefting (HP:0008428)2.53095392
77Bilateral sensorineural hearing impairment (HP:0008619)2.51971540
78Turricephaly (HP:0000262)2.51541857
79Abnormality of the lower motor neuron (HP:0002366)2.50938152
80Diplopia (HP:0000651)2.50435702
81Abnormality of binocular vision (HP:0011514)2.50435702
82Cerebral inclusion bodies (HP:0100314)2.50238372
83Hypoplasia of the iris (HP:0007676)2.49701506
84Paraparesis (HP:0002385)2.47579171
85Aplastic anemia (HP:0001915)2.47335446
86Absent epiphyses (HP:0010577)2.47199867
87Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.47199867
88Mixed hearing impairment (HP:0000410)2.43667314
89Atrial fibrillation (HP:0005110)2.41242326
90Supraventricular tachycardia (HP:0004755)2.39352469
91Bell-shaped thorax (HP:0001591)2.39219401
92Hypoplastic female external genitalia (HP:0012815)2.35774155
93Urethral obstruction (HP:0000796)2.35140675
94Supraventricular arrhythmia (HP:0005115)2.34976416
95Polycythemia (HP:0001901)2.32627493
96Broad metatarsal (HP:0001783)2.32493056
97Global brain atrophy (HP:0002283)2.31118104
98Deep venous thrombosis (HP:0002625)2.30134626
99Abnormality of macular pigmentation (HP:0008002)2.26352313
100Abnormality of the phalanges of the 2nd finger (HP:0009541)2.26236258
101Arterial tortuosity (HP:0005116)2.26025468
102Arnold-Chiari malformation (HP:0002308)2.24196451
103Preauricular pit (HP:0004467)2.21420329
104Periauricular skin pits (HP:0100277)2.21420329
105Anosmia (HP:0000458)2.20691694
106Arthropathy (HP:0003040)2.17897769
107Abnormal drinking behavior (HP:0030082)2.17434098
108Polydipsia (HP:0001959)2.17434098
109Hypotrichosis (HP:0001006)2.17204111
110Transposition of the great arteries (HP:0001669)2.16196505
111Abnormal connection of the cardiac segments (HP:0011545)2.16196505
112Abnormal ventriculo-arterial connection (HP:0011563)2.16196505
113Abnormality of the proximal phalanges of the hand (HP:0009834)2.14653461
114Exostoses (HP:0100777)2.14184941
115Concave nail (HP:0001598)2.10584508
116Enlarged epiphyses (HP:0010580)2.09932032
117Neurofibrillary tangles (HP:0002185)2.09912599
118Wormian bones (HP:0002645)2.09244591
119Ketoacidosis (HP:0001993)2.06368528
120Vascular tortuosity (HP:0004948)2.05549549
121Bony spicule pigmentary retinopathy (HP:0007737)2.04909256
122Urinary bladder sphincter dysfunction (HP:0002839)2.03486905
123Right ventricular cardiomyopathy (HP:0011663)2.03242095
124Hypoplasia of the uterus (HP:0000013)2.02859687
125Cerebral aneurysm (HP:0004944)2.02435562
126Annular pancreas (HP:0001734)2.00663707
127Abnormality of the axillary hair (HP:0100134)2.00082709
128Abnormality of secondary sexual hair (HP:0009888)2.00082709
129Tracheomalacia (HP:0002779)2.00070842
130Insomnia (HP:0100785)1.99138573
131Abnormality of DNA repair (HP:0003254)1.97895936
132Shallow orbits (HP:0000586)1.96910958
133Clubbing of toes (HP:0100760)1.96399718
134Molar tooth sign on MRI (HP:0002419)1.94488345
135Abnormality of midbrain morphology (HP:0002418)1.94488345
136Short thumb (HP:0009778)1.92334777
137Ectopic kidney (HP:0000086)1.91930022
138Focal segmental glomerulosclerosis (HP:0000097)1.91538676
139Hemiparesis (HP:0001269)1.91016796
140Short 5th finger (HP:0009237)1.90820867
141Supranuclear gaze palsy (HP:0000605)1.90525815
142Tarsal synostosis (HP:0008368)1.90264632
143Hypothermia (HP:0002045)1.89337493
144Abnormality of the pubic bones (HP:0003172)1.88920065
145Scrotal hypoplasia (HP:0000046)1.88906390
146Aplasia/Hypoplasia of the uvula (HP:0010293)1.88719995
147Amyloidosis (HP:0011034)1.88343430
148Truncal obesity (HP:0001956)1.88168277
149Hypokalemia (HP:0002900)1.88145113
150Ventricular fibrillation (HP:0001663)1.86479679
151Renal tubular acidosis (HP:0001947)1.84690818
152Plantar hyperkeratosis (HP:0007556)1.84407181
153Abnormality of the preputium (HP:0100587)1.84038909
154Abnormal respiratory epithelium morphology (HP:0012253)1.82515216
155Abnormal respiratory motile cilium morphology (HP:0005938)1.82515216
156Flattened epiphyses (HP:0003071)1.82494547
157Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.82398686
158Degeneration of the lateral corticospinal tracts (HP:0002314)1.82398686
159Xanthomatosis (HP:0000991)1.82297145
160Follicular hyperkeratosis (HP:0007502)1.81318623
161Hypercalciuria (HP:0002150)1.81022145
162Abnormality of the vitreous humor (HP:0004327)1.80582977
163Abnormality of monocarboxylic acid metabolism (HP:0010996)1.80099541
164Bulbar palsy (HP:0001283)1.78888609
165Delayed CNS myelination (HP:0002188)1.78437871
166Beaking of vertebral bodies (HP:0004568)1.78290690
167Bradycardia (HP:0001662)1.77437370
168Hypercortisolism (HP:0001578)1.76177813
169Milia (HP:0001056)1.75894009
170Absence seizures (HP:0002121)1.75636200
171Aplasia/Hypoplasia of the 5th finger (HP:0006262)1.75514279
172Premature rupture of membranes (HP:0001788)1.75353286
173Thoracolumbar scoliosis (HP:0002944)1.75094979
174Spastic diplegia (HP:0001264)1.73066485
175Generalized tonic-clonic seizures (HP:0002069)1.72345407
176Abnormal respiratory motile cilium physiology (HP:0012261)1.71912717
177Depression (HP:0000716)1.71566615
178Adrenal overactivity (HP:0002717)1.69023456
179Insidious onset (HP:0003587)1.68506306
180Termporal pattern (HP:0011008)1.68506306
181Morphological abnormality of the middle ear (HP:0008609)1.67087474
182Synostosis involving bones of the feet (HP:0009140)1.66376206
183Synostosis involving bones of the lower limbs (HP:0009138)1.66376206
184Abnormality of potassium homeostasis (HP:0011042)1.66107488
185Abnormal ciliary motility (HP:0012262)1.65806913
186Enlarged penis (HP:0000040)1.64797481
187Osteolytic defects of the hand bones (HP:0009699)1.63039433
188Osteolytic defects of the phalanges of the hand (HP:0009771)1.63039433
189Abnormal cartilage morphology (HP:0002763)1.62337704
190Hyperglycinuria (HP:0003108)1.61808181
191Ankle contracture (HP:0006466)1.61664130
192Back pain (HP:0003418)1.59231081
193Ketosis (HP:0001946)1.59199369
194Chronic bronchitis (HP:0004469)1.57849894
195Aortic dissection (HP:0002647)1.57353207
196Abnormality of glycine metabolism (HP:0010895)1.56588752

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA27.18165371
2GRK16.42184179
3STK38L3.40271441
4TYRO33.37420081
5MAPK153.34730693
6RIPK13.06573522
7PAK32.92504347
8SIK12.58124060
9TRIB32.57536370
10CAMK2D2.33738720
11STK392.32498543
12ADRBK22.31414630
13CAMK2B2.29536080
14SIK22.28380792
15DAPK21.94246680
16LMTK21.94038082
17PKN21.83109519
18HIPK21.75678306
19MAP3K11.70416598
20CAMK2G1.67438087
21CSNK1A1L1.65668972
22ERBB31.64914842
23DDR21.61829576
24STK381.57027427
25MAP3K31.56303068
26FRK1.55302638
27EEF2K1.55037772
28LATS11.52772830
29TGFBR21.45477057
30FER1.45070168
31MAP3K21.43436257
32NTRK11.40133541
33GRK61.37738806
34TBK11.37629018
35SIK31.37458215
36ERBB41.35859975
37IKBKB1.35463889
38TNK21.34957787
39CSNK1G21.27242937
40CSNK1G31.25607617
41PAK61.25306482
42ALK1.25200291
43EPHB11.21366034
44WEE11.18249941
45CHUK1.17572133
46CSNK1G11.15904215
47MAP2K41.13250090
48FGFR21.12062423
49OXSR11.11800394
50NME11.10809489
51PRKD21.10539750
52MINK11.09890224
53MST1R1.09558752
54MAP3K41.09515826
55MAP3K71.08484306
56MAPKAPK31.08317450
57TESK11.07760039
58NEK11.05941969
59TAOK21.05779937
60MAP2K11.05512841
61CDK41.04516551
62TTN1.04329902
63RPS6KA61.02633631
64ABL21.01010361
65PRKCG0.97240205
66DYRK1A0.96739240
67KSR20.95589327
68RPS6KC10.94906305
69RPS6KL10.94906305
70SCYL20.94819220
71LRRK20.94460878
72ERN10.93936934
73PTK60.93000858
74PRKD10.89666002
75FGFR30.89548256
76PRKCH0.88301193
77PRKD30.88090976
78CAMKK10.85112008
79MAPK70.84982737
80BRSK20.84712182
81PTK2B0.83350667
82PDGFRA0.82317419
83PRKG20.81898080
84PDK40.80974266
85PDK30.80974266
86ROCK20.80119086
87TAOK30.77907749
88TSSK60.75258007
89PDPK10.73868197
90NME20.73124896
91CAMK2A0.72221578
92CDK50.71538537
93WNK40.69556504
94TTK0.69293065
95MTOR0.68822763
96MARK20.68657540
97CDK60.67631416
98BMX0.67565236
99FYN0.65724138
100RET0.65569751
101EPHB20.65514836
102MARK10.64169949
103MAP3K60.63537119
104MAP3K100.61887025
105RPS6KA20.61767880
106NTRK30.59915850
107IKBKE0.59423013
108PHKG10.58731768
109PHKG20.58731768
110RPS6KA10.57826495
111ITK0.57745513
112PAK20.57076101
113PRKCI0.56296151
114DAPK10.55838777
115TRPM70.54643738
116MAPKAPK20.53856073
117ICK0.53168112
118LATS20.52076104
119MAP3K90.51639955
120MAP2K20.49843699
121ERBB20.49657092
122MAPK120.49572298
123MAP3K140.49426448
124WNK10.49356486
125STK30.49258369
126RPS6KB20.48720043
127CSK0.48608984
128SMG10.47747379
129TAOK10.47508806
130ADRBK10.47327728
131PTK20.46835420
132INSRR0.46676357
133MET0.46500514
134GSK3A0.46022369
135PKN10.45950005
136MYLK0.45510054
137LIMK10.44993820
138DYRK1B0.44433154
139STK240.44083414
140KDR0.43748573
141ILK0.42725380
142PAK40.42636750
143UHMK10.42298253
144MAP2K30.41964488
145DAPK30.41880547
146FGR0.41774927
147PDK20.41743193
148IRAK10.40930900
149CSNK1E0.38966056
150PRKACG0.38329781
151MST40.37572124
152PRKCZ0.36871769
153PDGFRB0.36465641
154IRAK30.33666714
155TESK20.33336683
156MAP2K60.31635433
157MAP3K110.30843446
158KIT0.27928662
159ROCK10.25831854
160EGFR0.24891535
161MAP3K80.24523073
162PRKCE0.24137489
163MAPK30.22500247
164DYRK30.21816437
165CSNK1A10.21106400
166NEK60.20828766

Predicted pathways (KEGG)

RankGene SetZ-score
1Olfactory transduction_Homo sapiens_hsa047406.15037237
2Glutathione metabolism_Homo sapiens_hsa004803.21011497
3Caffeine metabolism_Homo sapiens_hsa002323.13765468
4Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.09591474
5Pentose and glucuronate interconversions_Homo sapiens_hsa000402.88888773
6Thyroid hormone synthesis_Homo sapiens_hsa049182.88715219
7Butanoate metabolism_Homo sapiens_hsa006502.79771975
8Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.73230179
9Vasopressin-regulated water reabsorption_Homo sapiens_hsa049622.51249096
10Cyanoamino acid metabolism_Homo sapiens_hsa004602.45123302
11Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.43910713
12Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.33543032
13ECM-receptor interaction_Homo sapiens_hsa045122.13250127
14Phototransduction_Homo sapiens_hsa047442.07808944
15Other glycan degradation_Homo sapiens_hsa005112.05558003
16Arachidonic acid metabolism_Homo sapiens_hsa005901.99921722
17Vitamin B6 metabolism_Homo sapiens_hsa007501.98768929
18Notch signaling pathway_Homo sapiens_hsa043301.92396052
19Salivary secretion_Homo sapiens_hsa049701.76451411
20Sphingolipid metabolism_Homo sapiens_hsa006001.75969737
21Protein digestion and absorption_Homo sapiens_hsa049741.73981580
22Tight junction_Homo sapiens_hsa045301.73308324
23Bile secretion_Homo sapiens_hsa049761.72802398
24Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.67323246
25Sulfur metabolism_Homo sapiens_hsa009201.66903623
26Lysine degradation_Homo sapiens_hsa003101.65046908
27Vibrio cholerae infection_Homo sapiens_hsa051101.62520292
28Histidine metabolism_Homo sapiens_hsa003401.57391732
29Steroid hormone biosynthesis_Homo sapiens_hsa001401.52986215
30Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.49763191
31Nitrogen metabolism_Homo sapiens_hsa009101.49656661
32beta-Alanine metabolism_Homo sapiens_hsa004101.46584100
33Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.41005065
34Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.40707539
35Linoleic acid metabolism_Homo sapiens_hsa005911.40502428
36Hepatitis C_Homo sapiens_hsa051601.39172590
37Gastric acid secretion_Homo sapiens_hsa049711.36787623
38Leukocyte transendothelial migration_Homo sapiens_hsa046701.30437876
39Bladder cancer_Homo sapiens_hsa052191.26222378
40Chemical carcinogenesis_Homo sapiens_hsa052041.22996393
41Morphine addiction_Homo sapiens_hsa050321.22031600
42Ether lipid metabolism_Homo sapiens_hsa005651.20414052
43Hedgehog signaling pathway_Homo sapiens_hsa043401.16812007
44Circadian entrainment_Homo sapiens_hsa047131.11411034
45Collecting duct acid secretion_Homo sapiens_hsa049661.10420858
46TNF signaling pathway_Homo sapiens_hsa046681.09173473
47alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.06234071
48Insulin secretion_Homo sapiens_hsa049111.04599250
49Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.01931557
50Drug metabolism - other enzymes_Homo sapiens_hsa009831.01348068
51GABAergic synapse_Homo sapiens_hsa047271.00811036
52Dopaminergic synapse_Homo sapiens_hsa047280.96577640
53Vitamin digestion and absorption_Homo sapiens_hsa049770.96496793
54Synaptic vesicle cycle_Homo sapiens_hsa047210.96378843
55Pyruvate metabolism_Homo sapiens_hsa006200.94638284
56Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.92110672
57Aldosterone synthesis and secretion_Homo sapiens_hsa049250.91595530
58Starch and sucrose metabolism_Homo sapiens_hsa005000.91470115
59Tryptophan metabolism_Homo sapiens_hsa003800.91257748
60Focal adhesion_Homo sapiens_hsa045100.90625863
61Estrogen signaling pathway_Homo sapiens_hsa049150.90584313
62Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.90230064
63Fatty acid degradation_Homo sapiens_hsa000710.88987218
64MAPK signaling pathway_Homo sapiens_hsa040100.88979427
65Small cell lung cancer_Homo sapiens_hsa052220.86712938
66Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.86519358
67Propanoate metabolism_Homo sapiens_hsa006400.85738776
68Retinol metabolism_Homo sapiens_hsa008300.84551650
69Serotonergic synapse_Homo sapiens_hsa047260.84434735
70Transcriptional misregulation in cancer_Homo sapiens_hsa052020.84378580
71ABC transporters_Homo sapiens_hsa020100.82132517
72Basal cell carcinoma_Homo sapiens_hsa052170.81032701
73Phospholipase D signaling pathway_Homo sapiens_hsa040720.79385693
74cAMP signaling pathway_Homo sapiens_hsa040240.79153039
75Fructose and mannose metabolism_Homo sapiens_hsa000510.77774752
76Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.76922063
77Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.75173563
78Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.74994173
79Primary bile acid biosynthesis_Homo sapiens_hsa001200.74936300
80Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.74604062
81Arginine biosynthesis_Homo sapiens_hsa002200.73694910
82Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.71051863
83Glutamatergic synapse_Homo sapiens_hsa047240.70640136
84Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.70293920
85Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.70036705
86Neurotrophin signaling pathway_Homo sapiens_hsa047220.69452926
87Cholinergic synapse_Homo sapiens_hsa047250.68647038
88Ovarian steroidogenesis_Homo sapiens_hsa049130.64043535
892-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.63263347
90Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.63117729
91Toll-like receptor signaling pathway_Homo sapiens_hsa046200.62302149
92Thyroid hormone signaling pathway_Homo sapiens_hsa049190.62247323
93Renin secretion_Homo sapiens_hsa049240.61512529
94GnRH signaling pathway_Homo sapiens_hsa049120.61335897
95cGMP-PKG signaling pathway_Homo sapiens_hsa040220.61290478
96PI3K-Akt signaling pathway_Homo sapiens_hsa041510.60995093
97ErbB signaling pathway_Homo sapiens_hsa040120.60730487
98Hippo signaling pathway_Homo sapiens_hsa043900.60117694
99NF-kappa B signaling pathway_Homo sapiens_hsa040640.60003737
100Taste transduction_Homo sapiens_hsa047420.58578595
101Inositol phosphate metabolism_Homo sapiens_hsa005620.58328030
102Axon guidance_Homo sapiens_hsa043600.57747391
103Dilated cardiomyopathy_Homo sapiens_hsa054140.56057064
104Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.53835061
105Choline metabolism in cancer_Homo sapiens_hsa052310.53238690
106Melanogenesis_Homo sapiens_hsa049160.53109008
107Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.52435533
108Ras signaling pathway_Homo sapiens_hsa040140.52280941
109HIF-1 signaling pathway_Homo sapiens_hsa040660.51790735
110Toxoplasmosis_Homo sapiens_hsa051450.51572949
111Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.50836386
112Pancreatic secretion_Homo sapiens_hsa049720.50696267
113mTOR signaling pathway_Homo sapiens_hsa041500.50402173
114Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.50272877
115Prostate cancer_Homo sapiens_hsa052150.49236384
116Gap junction_Homo sapiens_hsa045400.48144751
117Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.48066854
118Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.47567283
119Amphetamine addiction_Homo sapiens_hsa050310.46894388
120Oxytocin signaling pathway_Homo sapiens_hsa049210.46086828
121Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.45922291
122B cell receptor signaling pathway_Homo sapiens_hsa046620.44344666
123VEGF signaling pathway_Homo sapiens_hsa043700.43730895
124Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.40888770
125Phenylalanine metabolism_Homo sapiens_hsa003600.39111857
126Calcium signaling pathway_Homo sapiens_hsa040200.38806443
127PPAR signaling pathway_Homo sapiens_hsa033200.38664585
128Glycerolipid metabolism_Homo sapiens_hsa005610.38514004
129Prion diseases_Homo sapiens_hsa050200.38159816
130Chronic myeloid leukemia_Homo sapiens_hsa052200.37294344
131Vascular smooth muscle contraction_Homo sapiens_hsa042700.36221958
132Longevity regulating pathway - mammal_Homo sapiens_hsa042110.35335970
133Fatty acid biosynthesis_Homo sapiens_hsa000610.35165571
134Amoebiasis_Homo sapiens_hsa051460.33972053
135Arginine and proline metabolism_Homo sapiens_hsa003300.33951109
136Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.33088824
137Rap1 signaling pathway_Homo sapiens_hsa040150.31352704
138Selenocompound metabolism_Homo sapiens_hsa004500.30739078
139Long-term potentiation_Homo sapiens_hsa047200.30724856
140Cocaine addiction_Homo sapiens_hsa050300.30405910
141Adherens junction_Homo sapiens_hsa045200.30400119
142Insulin resistance_Homo sapiens_hsa049310.29134149
143Platelet activation_Homo sapiens_hsa046110.28655184
144Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.27864524
145Fatty acid metabolism_Homo sapiens_hsa012120.26433284
146Carbohydrate digestion and absorption_Homo sapiens_hsa049730.24643072
147Dorso-ventral axis formation_Homo sapiens_hsa043200.23404803
148Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.23069469
149Sulfur relay system_Homo sapiens_hsa041220.22314152
150Adipocytokine signaling pathway_Homo sapiens_hsa049200.21739066
151Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.21478279
152Type II diabetes mellitus_Homo sapiens_hsa049300.21371253
153Cysteine and methionine metabolism_Homo sapiens_hsa002700.21144502
154Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.18562041

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