OCEL1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1L-phenylalanine metabolic process (GO:0006558)6.93495744
2erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)6.93495744
3L-phenylalanine catabolic process (GO:0006559)6.73888530
4erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)6.73888530
5aromatic amino acid family catabolic process (GO:0009074)5.63774189
6proteasome assembly (GO:0043248)5.51876792
7triglyceride-rich lipoprotein particle remodeling (GO:0034370)5.35825194
8cysteine metabolic process (GO:0006534)5.20273351
9serine family amino acid catabolic process (GO:0009071)5.08421897
10glyoxylate metabolic process (GO:0046487)5.05741356
11bile acid biosynthetic process (GO:0006699)4.94622396
12kynurenine metabolic process (GO:0070189)4.87853293
13tryptophan catabolic process (GO:0006569)4.87644219
14indole-containing compound catabolic process (GO:0042436)4.87644219
15indolalkylamine catabolic process (GO:0046218)4.87644219
16urea cycle (GO:0000050)4.85029623
17urea metabolic process (GO:0019627)4.85029623
18GDP-mannose metabolic process (GO:0019673)4.83252553
19sulfur amino acid catabolic process (GO:0000098)4.82969896
20glycine metabolic process (GO:0006544)4.77992537
21fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.77692099
22regulation of triglyceride catabolic process (GO:0010896)4.69104353
23alpha-linolenic acid metabolic process (GO:0036109)4.62960679
24tryptophan metabolic process (GO:0006568)4.54934803
25nitrogen cycle metabolic process (GO:0071941)4.49911239
26amino-acid betaine metabolic process (GO:0006577)4.44947315
27serine family amino acid metabolic process (GO:0009069)4.38284085
28bile acid metabolic process (GO:0008206)4.32820131
29lysine catabolic process (GO:0006554)4.28955562
30lysine metabolic process (GO:0006553)4.28955562
31negative regulation of fibrinolysis (GO:0051918)4.21355793
32high-density lipoprotein particle remodeling (GO:0034375)4.19850500
33homocysteine metabolic process (GO:0050667)4.17088091
34complement activation, alternative pathway (GO:0006957)4.16114152
35purine deoxyribonucleotide catabolic process (GO:0009155)4.15078432
36aromatic amino acid family metabolic process (GO:0009072)4.14629692
37L-fucose catabolic process (GO:0042355)4.12710828
38fucose catabolic process (GO:0019317)4.12710828
39L-fucose metabolic process (GO:0042354)4.12710828
40viral transcription (GO:0019083)4.11833413
41regulation of cholesterol homeostasis (GO:2000188)4.10906709
42regulation of fibrinolysis (GO:0051917)4.09618223
43short-chain fatty acid metabolic process (GO:0046459)4.08201453
44regulation of protein activation cascade (GO:2000257)4.08137152
45protein carboxylation (GO:0018214)4.05508557
46peptidyl-glutamic acid carboxylation (GO:0017187)4.05508557
47ethanol oxidation (GO:0006069)4.04452206
48alpha-amino acid catabolic process (GO:1901606)4.01417307
49serine family amino acid biosynthetic process (GO:0009070)3.97188334
50acylglycerol homeostasis (GO:0055090)3.94592519
51triglyceride homeostasis (GO:0070328)3.94592519
52regulation of bile acid biosynthetic process (GO:0070857)3.94264934
53translational termination (GO:0006415)3.89315237
54negative regulation of sterol transport (GO:0032372)3.88730344
55negative regulation of cholesterol transport (GO:0032375)3.88730344
56drug catabolic process (GO:0042737)3.86150881
57macromolecular complex remodeling (GO:0034367)3.80695738
58plasma lipoprotein particle remodeling (GO:0034369)3.80695738
59protein-lipid complex remodeling (GO:0034368)3.80695738
60regulation of complement activation (GO:0030449)3.78979555
61cellular ketone body metabolic process (GO:0046950)3.78666847
62cellular modified amino acid catabolic process (GO:0042219)3.77156447
63GTP biosynthetic process (GO:0006183)3.76385992
64cellular amino acid catabolic process (GO:0009063)3.74200154
65bile acid and bile salt transport (GO:0015721)3.73209199
66regulation of cholesterol esterification (GO:0010872)3.72874214
67fatty acid beta-oxidation (GO:0006635)3.70785082
68plasma lipoprotein particle clearance (GO:0034381)3.67013347
69ubiquinone biosynthetic process (GO:0006744)3.66243645
70drug transmembrane transport (GO:0006855)3.65966168
71reverse cholesterol transport (GO:0043691)3.65914002
72glutamate metabolic process (GO:0006536)3.62865047
73plasma lipoprotein particle assembly (GO:0034377)3.61451048
74phospholipid efflux (GO:0033700)3.57886898
75carnitine metabolic process (GO:0009437)3.56160305
76fatty acid oxidation (GO:0019395)3.56142321
77protein complex biogenesis (GO:0070271)3.56130448
78coenzyme catabolic process (GO:0009109)3.56066303
79behavioral response to nicotine (GO:0035095)3.56000460
80negative regulation of B cell apoptotic process (GO:0002903)3.55918557
81quinone biosynthetic process (GO:1901663)3.55680294
82respiratory chain complex IV assembly (GO:0008535)3.53591842
83imidazole-containing compound metabolic process (GO:0052803)3.53253741
84fatty acid catabolic process (GO:0009062)3.52915821
85monocarboxylic acid catabolic process (GO:0072329)3.51621040
86tyrosine metabolic process (GO:0006570)3.51200272
87UTP metabolic process (GO:0046051)3.50985638
88positive regulation of triglyceride lipase activity (GO:0061365)3.49971370
89positive regulation of lipoprotein lipase activity (GO:0051006)3.49971370
90base-excision repair, AP site formation (GO:0006285)3.48210906
91lipid oxidation (GO:0034440)3.48001252
92cholesterol homeostasis (GO:0042632)3.47278085
93carboxylic acid catabolic process (GO:0046395)3.46433734
94organic acid catabolic process (GO:0016054)3.46433734
95cytochrome complex assembly (GO:0017004)3.44903284
96cellular glucuronidation (GO:0052695)3.43505822
97positive regulation of triglyceride metabolic process (GO:0090208)3.43185070
98flavonoid metabolic process (GO:0009812)3.42213129
99DNA deamination (GO:0045006)3.41460971
100sterol homeostasis (GO:0055092)3.40850381
1012-oxoglutarate metabolic process (GO:0006103)3.39436562
102cellular biogenic amine catabolic process (GO:0042402)3.39280136
103amine catabolic process (GO:0009310)3.39280136
104positive regulation of fatty acid beta-oxidation (GO:0032000)3.39208126
105urate metabolic process (GO:0046415)3.38846795
106positive regulation of lipid catabolic process (GO:0050996)3.36463398
107aldehyde catabolic process (GO:0046185)3.34850290
108translational elongation (GO:0006414)3.33390653
109aspartate family amino acid catabolic process (GO:0009068)3.33130040
110regulation of triglyceride metabolic process (GO:0090207)3.32684510
111negative regulation of telomere maintenance (GO:0032205)3.31972129
112exogenous drug catabolic process (GO:0042738)3.31845482
113DNA damage response, detection of DNA damage (GO:0042769)3.31475091
114drug transport (GO:0015893)3.31072602
115very-low-density lipoprotein particle assembly (GO:0034379)3.30421359
116intestinal cholesterol absorption (GO:0030299)3.30395400
117mitochondrial respiratory chain complex I assembly (GO:0032981)3.29940926
118NADH dehydrogenase complex assembly (GO:0010257)3.29940926
119mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.29940926
120benzene-containing compound metabolic process (GO:0042537)3.29647165
121phospholipid homeostasis (GO:0055091)3.29161060
122acetyl-CoA metabolic process (GO:0006084)3.27761590
123UTP biosynthetic process (GO:0006228)3.26774216
124mannosylation (GO:0097502)3.16617604
125mitochondrial respiratory chain complex assembly (GO:0033108)3.15728155
126ubiquinone metabolic process (GO:0006743)3.12659338
127fucosylation (GO:0036065)3.09698220
128mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.98780953
129electron transport chain (GO:0022900)2.91230082
130respiratory electron transport chain (GO:0022904)2.88336830
131energy coupled proton transport, down electrochemical gradient (GO:0015985)2.84135943
132ATP synthesis coupled proton transport (GO:0015986)2.84135943
133deoxyribonucleotide catabolic process (GO:0009264)2.82082399
134purine deoxyribonucleotide metabolic process (GO:0009151)2.80043572
135cellular response to ATP (GO:0071318)2.77009848
136transepithelial transport (GO:0070633)2.74128356
137metallo-sulfur cluster assembly (GO:0031163)2.71110844
138iron-sulfur cluster assembly (GO:0016226)2.71110844
139platelet dense granule organization (GO:0060155)2.69275852
140fucose metabolic process (GO:0006004)2.69140036
141regulation of B cell apoptotic process (GO:0002902)2.66898037
142mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.66488914
143cellular response to zinc ion (GO:0071294)2.66055952
144axonemal dynein complex assembly (GO:0070286)2.63596004
145arginine metabolic process (GO:0006525)2.59899150
146amino acid salvage (GO:0043102)2.59644943
147L-methionine salvage (GO:0071267)2.59644943
148L-methionine biosynthetic process (GO:0071265)2.59644943
149nucleoside transmembrane transport (GO:1901642)2.58459911
1503-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)2.57993659
151purine ribonucleoside bisphosphate metabolic process (GO:0034035)2.57993659
152phosphatidylglycerol biosynthetic process (GO:0006655)2.56596308
153folic acid metabolic process (GO:0046655)2.55682535
154quinone metabolic process (GO:1901661)2.54977581
155nucleotide transmembrane transport (GO:1901679)2.51548296
156nucleoside diphosphate phosphorylation (GO:0006165)2.51394800
157negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.50321744
158deoxyribose phosphate catabolic process (GO:0046386)2.50212126
159guanosine-containing compound biosynthetic process (GO:1901070)2.49476427
160preassembly of GPI anchor in ER membrane (GO:0016254)2.44256048
161RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.43429958
162tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.43429958
163water-soluble vitamin biosynthetic process (GO:0042364)2.40477234
164purine nucleoside triphosphate biosynthetic process (GO:0009145)2.39491504
165L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.39199678
166hydrogen ion transmembrane transport (GO:1902600)2.38349982
167GPI anchor biosynthetic process (GO:0006506)2.38173522
168regulation of guanylate cyclase activity (GO:0031282)2.37232571
169glutathione derivative metabolic process (GO:1901685)2.36818613
170glutathione derivative biosynthetic process (GO:1901687)2.36818613
171viral protein processing (GO:0019082)2.35994247
172S-adenosylmethionine metabolic process (GO:0046500)2.34835657
173purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.34671068
174dolichol-linked oligosaccharide biosynthetic process (GO:0006488)2.33019540
175NAD biosynthetic process (GO:0009435)2.32370696
176detection of light stimulus involved in visual perception (GO:0050908)2.30486500
177detection of light stimulus involved in sensory perception (GO:0050962)2.30486500
178CTP biosynthetic process (GO:0006241)2.28125333
179CTP metabolic process (GO:0046036)2.28125333
180negative regulation of T cell differentiation in thymus (GO:0033085)2.27893714
181proton transport (GO:0015992)2.27577626

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse8.85083889
2RXR_22158963_ChIP-Seq_LIVER_Mouse6.13997217
3PPARA_22158963_ChIP-Seq_LIVER_Mouse5.62345552
4LXR_22158963_ChIP-Seq_LIVER_Mouse4.72393071
5PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.56758155
6EGR1_23403033_ChIP-Seq_LIVER_Mouse4.37664030
7FOXO1_23066095_ChIP-Seq_LIVER_Mouse4.08265948
8CEBPA_23403033_ChIP-Seq_LIVER_Mouse3.83380064
9E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.33182949
10JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.81132408
11SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.76879403
12CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.72072429
13NR1I2_20693526_ChIP-Seq_LIVER_Mouse2.62456821
14NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.44239041
15HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.29710730
16CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human2.28866235
17KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.09775396
18TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.06197657
19* SRF_21415370_ChIP-Seq_HL-1_Mouse1.98424378
20* TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.93439338
21GABP_17652178_ChIP-ChIP_JURKAT_Human1.90458139
22YY1_22570637_ChIP-Seq_MALME-3M_Human1.90109655
23EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.88346556
24ETS1_20019798_ChIP-Seq_JURKAT_Human1.87475408
25TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.85018093
26PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.82144467
27VDR_21846776_ChIP-Seq_THP-1_Human1.79418838
28LXR_22292898_ChIP-Seq_THP-1_Human1.74135586
29EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.73379250
30P300_27268052_Chip-Seq_Bcells_Human1.73245776
31CTCF_20526341_ChIP-Seq_ESCs_Human1.72382886
32RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.71023406
33ERA_21632823_ChIP-Seq_H3396_Human1.66491005
34BP1_19119308_ChIP-ChIP_Hs578T_Human1.65538457
35RARG_19884340_ChIP-ChIP_MEFs_Mouse1.65249639
36IRF8_22096565_ChIP-ChIP_GC-B_Human1.63221678
37* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.61063488
38STAT6_21828071_ChIP-Seq_BEAS2B_Human1.55504771
39ZNF263_19887448_ChIP-Seq_K562_Human1.51017622
40SA1_27219007_Chip-Seq_Bcells_Human1.50398545
41* TAF2_19829295_ChIP-Seq_ESCs_Human1.46792331
42GABP_19822575_ChIP-Seq_HepG2_Human1.46342221
43YY1_21170310_ChIP-Seq_MESCs_Mouse1.46330599
44TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.44723577
45VDR_23849224_ChIP-Seq_CD4+_Human1.36520129
46* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.35441276
47STAT3_1855785_ChIP-Seq_MESCs_Mouse1.35139548
48EST1_17652178_ChIP-ChIP_JURKAT_Human1.35042292
49NANOG_20526341_ChIP-Seq_ESCs_Human1.31641436
50CTCF_27219007_Chip-Seq_Bcells_Human1.30578540
51LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.29532900
52MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.29349086
53THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.28443654
54* ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.27856910
55SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.26645819
56ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.25527721
57FOXP3_21729870_ChIP-Seq_TREG_Human1.25167054
58FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.24601208
59TET1_21451524_ChIP-Seq_MESCs_Mouse1.24200846
60NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.20410610
61SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.18547128
62SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.18215170
63THAP11_20581084_ChIP-Seq_MESCs_Mouse1.17674130
64RACK7_27058665_Chip-Seq_MCF-7_Human1.17663431
65SOX2_27498859_Chip-Seq_STOMACH_Mouse1.17378380
66RAC3_21632823_ChIP-Seq_H3396_Human1.16243984
67BCOR_27268052_Chip-Seq_Bcells_Human1.15764810
68RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human1.15594631
69SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.15470378
70SOX2_21211035_ChIP-Seq_LN229_Human1.15399518
71OCT4_20526341_ChIP-Seq_ESCs_Human1.14743801
72PU.1_20513432_ChIP-Seq_Bcells_Mouse1.11604058
73PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.10602901
74BRD4_27068464_Chip-Seq_AML-cells_Mouse1.10299163
75ELK3_25401928_ChIP-Seq_HUVEC_Human1.10061356
76HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.09654402
77ETS1_21867929_ChIP-Seq_TH2_Mouse1.09612517
78BCL6_27268052_Chip-Seq_Bcells_Human1.09498607
79SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.09447746
80RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.09374579
81HNF4A_19822575_ChIP-Seq_HepG2_Human1.09011933
82DCP1A_22483619_ChIP-Seq_HELA_Human1.08865603
83TP63_17297297_ChIP-ChIP_HaCaT_Human1.08649036
84SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.08510809
85PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.08349063
86SMC4_20622854_ChIP-Seq_HELA_Human1.08303862
87CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.07590482
88STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.06117123
89IRF8_21731497_ChIP-ChIP_J774_Mouse1.06083482
90P68_20966046_ChIP-Seq_HELA_Human1.05829277
91TCF7_22412390_ChIP-Seq_EML_Mouse1.05817077
92SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.05589193
93CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.05113207
94RXRA_24833708_ChIP-Seq_LIVER_Mouse1.04942104
95SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.04702679
96UTX_26944678_Chip-Seq_JUKART_Human1.04165102
97SA1_27219007_Chip-Seq_ERYTHROID_Human1.04005619
98PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.01515938
99* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.01288594
100MYC_22102868_ChIP-Seq_BL_Human1.01279139
101CTCF_21964334_Chip-Seq_Bcells_Human1.00969444
102GATA1_22025678_ChIP-Seq_K562_Human1.00357855
103CDX2_20551321_ChIP-Seq_CACO-2_Human1.00272077
104CTCF_21964334_ChIP-Seq_BJAB-B_Human0.99570454
105CLOCK_20551151_ChIP-Seq_293T_Human0.99477378
106GATA1_22383799_ChIP-Seq_G1ME_Mouse0.99256878
107FOXA2_19822575_ChIP-Seq_HepG2_Human0.98257564
108FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.98211529
109SRY_22984422_ChIP-ChIP_TESTIS_Rat0.98024568
110* MAF_26560356_Chip-Seq_TH1_Human0.97971016
111MAF_26560356_Chip-Seq_TH2_Human0.97847972
112ELF1_20517297_ChIP-Seq_JURKAT_Human0.96610626
113* VDR_24763502_ChIP-Seq_THP-1_Human0.96048352
114E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.95842171
115TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.93349186
116CTCF_27219007_Chip-Seq_ERYTHROID_Human0.92690293
117GATA2_22383799_ChIP-Seq_G1ME_Mouse0.91163938
118GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.90471891
119GATA4_25053715_ChIP-Seq_YYC3_Human0.89970236
120GATA6_25053715_ChIP-Seq_YYC3_Human0.89655914
121SPI1_20517297_ChIP-Seq_HL60_Human0.88529872
122XRN2_22483619_ChIP-Seq_HELA_Human0.87568731
123CTCF_26484167_Chip-Seq_Bcells_Mouse0.87099891
124* KDM2B_26808549_Chip-Seq_SUP-B15_Human0.87018816
125CTCF_18555785_ChIP-Seq_MESCs_Mouse0.86972200
126PHF8_20622854_ChIP-Seq_HELA_Human0.86378492
127RAD21_21589869_ChIP-Seq_MESCs_Mouse0.85670176
128DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.85289393
129ATF3_27146783_Chip-Seq_COLON_Human0.84684946
130E2F1_20622854_ChIP-Seq_HELA_Human0.83915155
131CREB1_26743006_Chip-Seq_LNCaP_Human0.83826850
132* KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.80645330
133* MYC_18358816_ChIP-ChIP_MESCs_Mouse0.80600047
134SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.80047509
135P53_21459846_ChIP-Seq_SAOS-2_Human0.78433739
136RARB_24833708_ChIP-Seq_LIVER_Mouse0.78020075
137BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.77781221
138RARA_24833708_ChIP-Seq_LIVER_Mouse0.77501571
139SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.77427359
140HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.77399827
141GATA1_19941827_ChIP-Seq_MEL_Mouse0.77094097
142FOXP1_21924763_ChIP-Seq_HESCs_Human0.76795889
143CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.76345863
144STAT1_20625510_ChIP-Seq_HELA_Human0.75720463
145BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.75566856
146ELF1_17652178_ChIP-ChIP_JURKAT_Human0.75311500
147* NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.75192987
148* MYC_18555785_ChIP-Seq_MESCs_Mouse0.74534045
149RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.74453908

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005360_urolithiasis7.18945641
2MP0002139_abnormal_hepatobiliary_system7.02041079
3MP0005085_abnormal_gallbladder_physiolo5.40234521
4MP0005365_abnormal_bile_salt5.11701937
5MP0008875_abnormal_xenobiotic_pharmacok4.24124503
6MP0003252_abnormal_bile_duct3.48713946
7MP0005083_abnormal_biliary_tract3.39769561
8MP0009840_abnormal_foam_cell3.12808184
9MP0010329_abnormal_lipoprotein_level2.97045734
10MP0003806_abnormal_nucleotide_metabolis2.96106716
11MP0001986_abnormal_taste_sensitivity2.89231124
12MP0001666_abnormal_nutrient_absorption2.73722884
13MP0005332_abnormal_amino_acid2.65034506
14MP0009379_abnormal_foot_pigmentation2.39038451
15MP0002876_abnormal_thyroid_physiology2.31182755
16MP0002138_abnormal_hepatobiliary_system2.20581644
17MP0004019_abnormal_vitamin_homeostasis2.18336026
18MP0003195_calcinosis2.12614133
19MP0004147_increased_porphyrin_level2.12432199
20MP0000609_abnormal_liver_physiology2.05237899
21MP0003191_abnormal_cellular_cholesterol2.02866947
22MP0003011_delayed_dark_adaptation1.86442125
23MP0005319_abnormal_enzyme/_coenzyme1.86219470
24MP0002736_abnormal_nociception_after1.83723840
25MP0002118_abnormal_lipid_homeostasis1.82686937
26MP0001968_abnormal_touch/_nociception1.77418251
27MP0009643_abnormal_urine_homeostasis1.67461553
28MP0003868_abnormal_feces_composition1.56756160
29MP0001764_abnormal_homeostasis1.47066054
30MP0002277_abnormal_respiratory_mucosa1.46765808
31MP0006082_CNS_inflammation1.46566439
32MP0005584_abnormal_enzyme/coenzyme_acti1.45472639
33MP0002653_abnormal_ependyma_morphology1.44606896
34MP0005410_abnormal_fertilization1.44129221
35MP0005551_abnormal_eye_electrophysiolog1.43521419
36MP0002837_dystrophic_cardiac_calcinosis1.42253650
37MP0005670_abnormal_white_adipose1.42165051
38MP0002148_abnormal_hypersensitivity_rea1.36118475
39MP0003300_gastrointestinal_ulcer1.35402995
40MP0001919_abnormal_reproductive_system1.34899523
41MP0003656_abnormal_erythrocyte_physiolo1.33796439
42MP0005671_abnormal_response_to1.33149280
43MP0005636_abnormal_mineral_homeostasis1.32079114
44MP0001790_abnormal_immune_system1.30371899
45MP0005387_immune_system_phenotype1.30371899
46MP0006036_abnormal_mitochondrial_physio1.30353378
47MP0003186_abnormal_redox_activity1.29089263
48MP0002735_abnormal_chemical_nociception1.27718155
49MP0005423_abnormal_somatic_nervous1.23693034
50MP0003172_abnormal_lysosome_physiology1.22684714
51MP0009785_altered_susceptibility_to1.21871304
52MP0009333_abnormal_splenocyte_physiolog1.21516390
53MP0005666_abnormal_adipose_tissue1.16353686
54MP0003705_abnormal_hypodermis_morpholog1.13552516
55MP0002723_abnormal_immune_serum1.12878797
56MP0000598_abnormal_liver_morphology1.11047893
57MP0001905_abnormal_dopamine_level1.10465282
58MP0001800_abnormal_humoral_immune1.10156922
59MP0005451_abnormal_body_composition1.10130009
60MP0005389_reproductive_system_phenotype1.09275971
61MP0001502_abnormal_circadian_rhythm1.08459659
62MP0002419_abnormal_innate_immunity1.06574197
63MP0008469_abnormal_protein_level1.03856683
64MP0000538_abnormal_urinary_bladder1.02375966
65MP0002160_abnormal_reproductive_system1.01885323
66MP0002796_impaired_skin_barrier1.01683834
67MP0001663_abnormal_digestive_system1.01281595
68MP0005084_abnormal_gallbladder_morpholo1.00556379
69MP0001835_abnormal_antigen_presentation0.98865455
70MP0002452_abnormal_antigen_presenting0.97283594
71MP0004130_abnormal_muscle_cell0.95927884
72MP0009764_decreased_sensitivity_to0.95568475
73MP0002693_abnormal_pancreas_physiology0.94518146
74MP0005220_abnormal_exocrine_pancreas0.94385559
75MP0001756_abnormal_urination0.94187121
76MP0009763_increased_sensitivity_to0.92717673
77MP0002132_abnormal_respiratory_system0.92466476
78MP0005377_hearing/vestibular/ear_phenot0.91350396
79MP0003878_abnormal_ear_physiology0.91350396
80MP0009642_abnormal_blood_homeostasis0.91312676
81MP0003718_maternal_effect0.91306449
82MP0001819_abnormal_immune_cell0.90947098
83MP0005000_abnormal_immune_tolerance0.90941125
84MP0002420_abnormal_adaptive_immunity0.90231236
85MP0010386_abnormal_urinary_bladder0.89638420
86MP0003786_premature_aging0.89338409
87MP0001873_stomach_inflammation0.87630099
88MP0002136_abnormal_kidney_physiology0.86768464
89MP0005253_abnormal_eye_physiology0.86407562
90MP0004142_abnormal_muscle_tone0.85738387
91MP0005381_digestive/alimentary_phenotyp0.85016128
92MP0002928_abnormal_bile_duct0.84685161
93MP0009384_cardiac_valve_regurgitation0.84323215
94MP0004381_abnormal_hair_follicle0.83433164
95MP0002971_abnormal_brown_adipose0.83430536
96MP0004185_abnormal_adipocyte_glucose0.83148329
97MP0003436_decreased_susceptibility_to0.82985315
98MP0005171_absent_coat_pigmentation0.82773000
99MP0002254_reproductive_system_inflammat0.82678293
100MP0003724_increased_susceptibility_to0.81372314
101MP0002733_abnormal_thermal_nociception0.81131401
102MP0005334_abnormal_fat_pad0.81079067
103MP0004145_abnormal_muscle_electrophysio0.79250322
104MP0004133_heterotaxia0.77454492
105MP0001765_abnormal_ion_homeostasis0.76896813
106MP0003075_altered_response_to0.76513261
107MP0005075_abnormal_melanosome_morpholog0.75175829
108MP0002909_abnormal_adrenal_gland0.74448364
109MP0002078_abnormal_glucose_homeostasis0.73443377
110MP0003303_peritoneal_inflammation0.72676176
111MP0010155_abnormal_intestine_physiology0.72230141
112MP0005375_adipose_tissue_phenotype0.72057041
113MP0005647_abnormal_sex_gland0.71564412
114MP0000604_amyloidosis0.70810019
115MP0005408_hypopigmentation0.70348948
116MP0009053_abnormal_anal_canal0.66289124
117MP0005464_abnormal_platelet_physiology0.61986784
118MP0005376_homeostasis/metabolism_phenot0.60653025
119MP0000685_abnormal_immune_system0.57667735
120MP0005501_abnormal_skin_physiology0.55320137
121MP0005330_cardiomyopathy0.55144173
122MP0001944_abnormal_pancreas_morphology0.53862126
123MP0001845_abnormal_inflammatory_respons0.53823750
124MP0003866_abnormal_defecation0.52388582
125MP0010368_abnormal_lymphatic_system0.50259388
126MP0006035_abnormal_mitochondrial_morpho0.49909811
127MP0005535_abnormal_body_temperature0.48812150
128MP0009765_abnormal_xenobiotic_induced0.48655808
129MP0001661_extended_life_span0.48363229
130MP0009672_abnormal_birth_weight0.48170229
131MP0002060_abnormal_skin_morphology0.48113446
132MP0005174_abnormal_tail_pigmentation0.47645750
133MP0005058_abnormal_lysosome_morphology0.47226611
134MP0003638_abnormal_response/metabolism_0.47052693
135MP0005166_decreased_susceptibility_to0.45368914
136MP0008961_abnormal_basal_metabolism0.44406176
137MP0000477_abnormal_intestine_morphology0.44042071
138MP0009115_abnormal_fat_cell0.43702423
139MP0001853_heart_inflammation0.43427919
140MP0002166_altered_tumor_susceptibility0.43364888
141MP0008872_abnormal_physiological_respon0.43005072
142MP0000230_abnormal_systemic_arterial0.42112801
143MP0005448_abnormal_energy_balance0.41105217
144MP0004043_abnormal_pH_regulation0.40827010
145MP0000462_abnormal_digestive_system0.39997395
146MP0003453_abnormal_keratinocyte_physiol0.39663931
147MP0002135_abnormal_kidney_morphology0.38832946
148MP0005025_abnormal_response_to0.38157772

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)6.36704605
2Intrahepatic cholestasis (HP:0001406)5.66023210
3Abnormality of monocarboxylic acid metabolism (HP:0010996)5.35273813
4Xanthomatosis (HP:0000991)5.24466533
5Deep venous thrombosis (HP:0002625)5.10075674
6Hyperglycinemia (HP:0002154)4.72261732
7Hypobetalipoproteinemia (HP:0003563)4.70295347
8Prolonged partial thromboplastin time (HP:0003645)4.59832745
9Hyperglycinuria (HP:0003108)4.32185268
10Abnormality of glycine metabolism (HP:0010895)4.16958169
11Abnormality of serine family amino acid metabolism (HP:0010894)4.16958169
12Ketosis (HP:0001946)4.14219920
13Hyperammonemia (HP:0001987)4.06942694
14Hyperlipoproteinemia (HP:0010980)4.02540640
15Mesangial abnormality (HP:0001966)4.02442959
16Abnormality of glutamine family amino acid metabolism (HP:0010902)3.82425887
17Complement deficiency (HP:0004431)3.78990700
18Increased hepatocellular lipid droplets (HP:0006565)3.55403742
19Hypoglycemic coma (HP:0001325)3.47683582
20Renal Fanconi syndrome (HP:0001994)3.45227989
21Hypolipoproteinemia (HP:0010981)3.41109052
22Abnormality of fatty-acid metabolism (HP:0004359)3.36995229
23Delayed CNS myelination (HP:0002188)3.32633756
24Fat malabsorption (HP:0002630)3.26804238
25Decreased electroretinogram (ERG) amplitude (HP:0000654)3.22283016
26Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.19858582
27Ketoacidosis (HP:0001993)3.17600380
28Joint hemorrhage (HP:0005261)3.12457808
29Abnormality of the level of lipoprotein cholesterol (HP:0010979)3.10506549
30Abnormal mitochondria in muscle tissue (HP:0008316)3.10172802
31Acute necrotizing encephalopathy (HP:0006965)3.07698228
32Malnutrition (HP:0004395)3.06998364
33Increased CSF lactate (HP:0002490)3.06737840
34Elevated erythrocyte sedimentation rate (HP:0003565)3.05133522
35Abnormality of the common coagulation pathway (HP:0010990)3.05011186
36Abnormality of dicarboxylic acid metabolism (HP:0010995)3.04985156
37Dicarboxylic aciduria (HP:0003215)3.04985156
38Abnormality of complement system (HP:0005339)3.04233727
39Epidermoid cyst (HP:0200040)3.01214617
40Congenital stationary night blindness (HP:0007642)2.93827536
41Hypoalphalipoproteinemia (HP:0003233)2.88607516
42Abnormality of sulfur amino acid metabolism (HP:0004339)2.87567052
43Hyperbilirubinemia (HP:0002904)2.87159597
44Abnormality of pyrimidine metabolism (HP:0004353)2.84826157
45Abnormal hemoglobin (HP:0011902)2.82835827
46Hypercholesterolemia (HP:0003124)2.82325007
47Abnormality of aspartate family amino acid metabolism (HP:0010899)2.81557943
48Gout (HP:0001997)2.76674965
49Exertional dyspnea (HP:0002875)2.75877770
50Hepatic necrosis (HP:0002605)2.73793781
51Cerebral edema (HP:0002181)2.73769549
52Attenuation of retinal blood vessels (HP:0007843)2.72529470
53Acanthocytosis (HP:0001927)2.70161467
54Late onset (HP:0003584)2.70076705
55Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.69345530
56Abnormality of nucleobase metabolism (HP:0010932)2.68177408
57Increased muscle lipid content (HP:0009058)2.67202551
58Metabolic acidosis (HP:0001942)2.63675148
59Macrocytic anemia (HP:0001972)2.63652660
60Lethargy (HP:0001254)2.61204452
61Abnormality of purine metabolism (HP:0004352)2.59853034
62Generalized aminoaciduria (HP:0002909)2.58867345
63Abnormality of serum amino acid levels (HP:0003112)2.55630441
64Glycosuria (HP:0003076)2.51689592
65Abnormality of urine glucose concentration (HP:0011016)2.51689592
66Hyperphosphaturia (HP:0003109)2.50592652
67Reduced antithrombin III activity (HP:0001976)2.48609208
68Conjugated hyperbilirubinemia (HP:0002908)2.47803351
69Increased serum lactate (HP:0002151)2.38804646
70Progressive macrocephaly (HP:0004481)2.37638260
71Lactic acidosis (HP:0003128)2.37396810
72Abnormality of the intrinsic pathway (HP:0010989)2.37046282
73Myocardial infarction (HP:0001658)2.35142244
74Vomiting (HP:0002013)2.34759747
75Hepatocellular necrosis (HP:0001404)2.30714343
76Reticulocytopenia (HP:0001896)2.30190135
77Abnormality of methionine metabolism (HP:0010901)2.30159124
78Increased intramyocellular lipid droplets (HP:0012240)2.29509902
79Abnormality of renal resorption (HP:0011038)2.29189654
80Hemorrhage of the eye (HP:0011885)2.27369987
81Abnormality of the Achilles tendon (HP:0005109)2.26749350
82Ileus (HP:0002595)2.23245463
83Lipid accumulation in hepatocytes (HP:0006561)2.21539254
84Chronic hepatic failure (HP:0100626)2.21383160
85Decreased central vision (HP:0007663)2.21204894
86Type I transferrin isoform profile (HP:0003642)2.20172567
87Optic disc pallor (HP:0000543)2.16681649
88Steatorrhea (HP:0002570)2.16327547
89Menorrhagia (HP:0000132)2.16128530
90Ragged-red muscle fibers (HP:0003200)2.15913348
91Acute encephalopathy (HP:0006846)2.15476027
92Abnormal respiratory motile cilium physiology (HP:0012261)2.15012432
93Spontaneous abortion (HP:0005268)2.14464865
94Exercise intolerance (HP:0003546)2.13888282
95Skin nodule (HP:0200036)2.12746158
96Systemic lupus erythematosus (HP:0002725)2.11235510
97Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.10677597
98Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.10638340
99Decreased activity of mitochondrial respiratory chain (HP:0008972)2.10638340
100Poikilocytosis (HP:0004447)2.10562254
101Stomatitis (HP:0010280)2.08558422
102Progressive microcephaly (HP:0000253)2.08016753
103Abnormal urine phosphate concentration (HP:0012599)2.06292613
104Hypophosphatemic rickets (HP:0004912)2.05325443
105Hepatocellular carcinoma (HP:0001402)2.05307885
106Microretrognathia (HP:0000308)2.05072938
107Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.04857791
108Abnormal ciliary motility (HP:0012262)2.04612495
109Bony spicule pigmentary retinopathy (HP:0007737)2.03463378
110Abnormality of midbrain morphology (HP:0002418)2.02509377
111Molar tooth sign on MRI (HP:0002419)2.02509377
112Dynein arm defect of respiratory motile cilia (HP:0012255)2.01699464
113Absent/shortened dynein arms (HP:0200106)2.01699464
114Nephronophthisis (HP:0000090)2.01189204
115Pancreatitis (HP:0001733)2.00338418
116Vascular calcification (HP:0004934)2.00314929
117Abnormal gallbladder morphology (HP:0012437)2.00286344
118Cholelithiasis (HP:0001081)1.99917486
119Large eyes (HP:0001090)1.99731123
1203-Methylglutaconic aciduria (HP:0003535)1.99481828
121Proximal tubulopathy (HP:0000114)1.98092134
122Abnormal respiratory motile cilium morphology (HP:0005938)1.97798618
123Abnormal respiratory epithelium morphology (HP:0012253)1.97798618
124Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.95234929
125Abnormal protein N-linked glycosylation (HP:0012347)1.95234929
126Abnormal protein glycosylation (HP:0012346)1.95234929
127Abnormal glycosylation (HP:0012345)1.95234929
128Facial diplegia (HP:0001349)1.93402656
129Abnormality of polysaccharide metabolism (HP:0011012)1.93195020
130Abnormality of glycosaminoglycan metabolism (HP:0004371)1.93195020
131Abnormality of mucopolysaccharide metabolism (HP:0011020)1.93195020
132Neonatal onset (HP:0003623)1.92180753
133Testicular atrophy (HP:0000029)1.90297334
134True hermaphroditism (HP:0010459)1.88750125
135Abnormality of dental color (HP:0011073)1.88406559
136Esophageal varix (HP:0002040)1.87819250
137Abnormality of reticulocytes (HP:0004312)1.86427582
138Polycythemia (HP:0001901)1.85736637
139Respiratory difficulties (HP:0002880)1.85222974
140Petechiae (HP:0000967)1.85063855
141Abnormality of cells of the erythroid lineage (HP:0012130)1.84224215
142Abnormality of proline metabolism (HP:0010907)1.84072413
143Hydroxyprolinuria (HP:0003080)1.84072413
144Irritability (HP:0000737)1.83830455
145Mitochondrial inheritance (HP:0001427)1.83357233
146Abnormality of the gallbladder (HP:0005264)1.83229479
147Abnormality of transition element cation homeostasis (HP:0011030)1.82899293
148Pancreatic cysts (HP:0001737)1.82655054
149Increased serum ferritin (HP:0003281)1.82571889
150Spastic diplegia (HP:0001264)1.82014719
151Myositis (HP:0100614)1.80901704
152Impaired platelet aggregation (HP:0003540)1.80575114
153Abnormal platelet function (HP:0011869)1.80575114
154Alkalosis (HP:0001948)1.80295882
155Nausea (HP:0002018)1.80267413
156Glomerulonephritis (HP:0000099)1.80151919
157Cerebral palsy (HP:0100021)1.79776759
158Abnormal rod and cone electroretinograms (HP:0008323)1.79560127
159Abnormal albumin level (HP:0012116)1.78935596
160Hypoalbuminemia (HP:0003073)1.78935596
161Pallor (HP:0000980)1.78924530
162Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.78916457
163Abnormality of alanine metabolism (HP:0010916)1.78916457
164Hyperalaninemia (HP:0003348)1.78916457
165Abnormal number of erythroid precursors (HP:0012131)1.78264644
166CNS demyelination (HP:0007305)1.76335806

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TLK17.13427121
2BCKDK4.03604423
3ERN13.59190581
4TRIB33.17903659
5MAP3K103.12325489
6PKN22.85257229
7VRK22.62736315
8FGFR42.49981128
9TESK22.44560699
10NME22.44281697
11SIK12.33146896
12MUSK2.29258751
13FLT32.17000723
14ACVR1B2.02081120
15TXK1.97492730
16CDK191.97205492
17TAOK31.95724561
18LMTK21.76731034
19ADRBK21.69180732
20GRK11.64703354
21PIM21.62201420
22PIK3CG1.62153558
23WNK41.60113844
24PINK11.57712629
25DAPK31.51713827
26INSRR1.45850157
27MST1R1.45411607
28MAP4K21.44357540
29GRK61.41432320
30TESK11.40545453
31MAPK111.39153717
32LRRK21.38965366
33BMPR1B1.34262670
34MAP3K111.33242270
35TNK21.32092813
36PTK61.25318241
37TTN1.24532153
38ARAF1.21100374
39OXSR11.19830206
40MAP3K71.16541175
41CAMKK21.14845459
42MAPK151.13144421
43TYK21.12962509
44EPHB11.10228360
45DYRK1B1.10103420
46ZAK1.07632197
47NME11.07521963
48TBK11.06182886
49KDR1.04071426
50MAP4K11.03275881
51EEF2K1.02946702
52ADRBK11.02599649
53IRAK31.01828480
54NEK91.01621327
55SIK21.00502487
56IRAK40.98572340
57PDK30.95722110
58PDK40.95722110
59TGFBR20.91896237
60MYLK0.91861453
61LIMK10.91000187
62PRKAA20.89750406
63MAP2K30.88649844
64MAP3K120.87198801
65EPHB20.86903138
66BTK0.86669108
67SYK0.85731319
68ILK0.79502305
69JAK20.78947950
70IRAK10.76894141
71ICK0.76629078
72ERBB40.76409522
73RIPK40.76054284
74TAOK10.74752949
75BLK0.74538468
76MAP2K20.73469410
77PDK20.73151316
78PTK2B0.70832777
79EPHA20.69762239
80CCNB10.69154826
81RPS6KA40.69089997
82ZAP700.67930799
83SIK30.67031965
84RIPK10.65810850
85FRK0.65247444
86LYN0.64637582
87ABL20.63719014
88RPS6KA60.60196842
89IKBKE0.59841143
90ERBB20.58901915
91MATK0.57934560
92RPS6KA20.55236438
93PDPK10.55033118
94PRKG20.54794650
95CSF1R0.54462316
96TEC0.54069373
97BRAF0.53844325
98PRKCI0.53593377
99RPS6KA50.51534316
100CDK40.50982716
101DAPK10.50962702
102CAMK1D0.50644566
103STK390.49399607
104PRKD10.49274201
105DYRK30.49104761
106STK100.48119930
107PRKD20.46937770
108FES0.46834501
109MAPK40.45712386
110MAPK120.45628618
111MAP2K60.45298929
112MAP3K80.44481313
113PTK20.44462711
114NLK0.44453893
115MAPKAPK30.43775226
116LCK0.43647884
117MAP2K70.43468924
118NUAK10.43374316
119AURKA0.43286396
120PAK10.42815844
121DYRK20.42555117
122RPS6KC10.42308593
123RPS6KL10.42308593
124KIT0.41311122
125CSK0.41162018
126JAK10.40932578
127TRIM280.39613855
128CSNK1G30.38192579
129PKN10.38069094
130STK40.37520068
131MAP3K10.37492451
132TIE10.36767411
133HIPK20.36224112
134PRKACA0.35965471
135PRKCD0.35172776
136PRKCQ0.35053982
137STK160.34396993
138RPS6KB20.34335264
139MAP3K30.33789230
140MAP3K140.33725995
141PRKCA0.33276944
142IRAK20.32854012
143PHKG20.31387731
144PHKG10.31387731
145MAP2K40.29779442
146EPHA30.28791579
147ITK0.28201369
148CAMK40.27610951
149MTOR0.26918625
150NEK20.26717128
151IKBKB0.26524060
152PDK10.25800094
153CDC42BPA0.25728424
154CDK90.25674290
155DAPK20.23906201

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001203.95608457
2Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.18079269
3Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.80247659
4Fatty acid degradation_Homo sapiens_hsa000712.72611034
5Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.71855051
6Nitrogen metabolism_Homo sapiens_hsa009102.67631562
7Tryptophan metabolism_Homo sapiens_hsa003802.55199308
8Arginine biosynthesis_Homo sapiens_hsa002202.53481420
9Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.43367165
10Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.41013745
11Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.39346750
12Sulfur relay system_Homo sapiens_hsa041222.33665009
13Pentose and glucuronate interconversions_Homo sapiens_hsa000402.30735564
14Complement and coagulation cascades_Homo sapiens_hsa046102.15567612
15Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.08661266
16Propanoate metabolism_Homo sapiens_hsa006402.08158232
17Butanoate metabolism_Homo sapiens_hsa006502.07744231
18Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.07327327
19Peroxisome_Homo sapiens_hsa041462.00760366
20Selenocompound metabolism_Homo sapiens_hsa004501.95867198
21PPAR signaling pathway_Homo sapiens_hsa033201.94774145
22Caffeine metabolism_Homo sapiens_hsa002321.93304878
23Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.91844983
24Ribosome_Homo sapiens_hsa030101.91460797
25Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.88732086
26Cyanoamino acid metabolism_Homo sapiens_hsa004601.81496681
27Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.81234445
28Histidine metabolism_Homo sapiens_hsa003401.71059063
29Folate biosynthesis_Homo sapiens_hsa007901.70621288
30Fatty acid metabolism_Homo sapiens_hsa012121.69280301
31Chemical carcinogenesis_Homo sapiens_hsa052041.66997734
32Drug metabolism - other enzymes_Homo sapiens_hsa009831.66498463
33Maturity onset diabetes of the young_Homo sapiens_hsa049501.65565562
34Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.60645148
35Fat digestion and absorption_Homo sapiens_hsa049751.59909951
36Pyruvate metabolism_Homo sapiens_hsa006201.59042684
37Glycosaminoglycan degradation_Homo sapiens_hsa005311.56588808
38beta-Alanine metabolism_Homo sapiens_hsa004101.56499368
39Proteasome_Homo sapiens_hsa030501.55138879
40Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.53013278
41Sulfur metabolism_Homo sapiens_hsa009201.45248476
42Bile secretion_Homo sapiens_hsa049761.44247383
43Retinol metabolism_Homo sapiens_hsa008301.43707230
44Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.40713635
452-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.37233264
46Carbon metabolism_Homo sapiens_hsa012001.37096173
47Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.35032194
48Staphylococcus aureus infection_Homo sapiens_hsa051501.29684346
49Steroid hormone biosynthesis_Homo sapiens_hsa001401.26621660
50One carbon pool by folate_Homo sapiens_hsa006701.25518301
51Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.24222890
52Starch and sucrose metabolism_Homo sapiens_hsa005001.21266838
53Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.19840848
54Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.15104513
55Phenylalanine metabolism_Homo sapiens_hsa003601.14544873
56ABC transporters_Homo sapiens_hsa020101.13163012
57Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.09364766
58Lysine degradation_Homo sapiens_hsa003101.08207608
59Base excision repair_Homo sapiens_hsa034101.07944118
60Biosynthesis of amino acids_Homo sapiens_hsa012301.04898666
61Intestinal immune network for IgA production_Homo sapiens_hsa046721.02720867
62Tyrosine metabolism_Homo sapiens_hsa003501.01798960
63Pentose phosphate pathway_Homo sapiens_hsa000301.00052116
64Primary immunodeficiency_Homo sapiens_hsa053400.99496954
65Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.99147363
66RNA polymerase_Homo sapiens_hsa030200.97567890
67Fatty acid elongation_Homo sapiens_hsa000620.96916756
68Cysteine and methionine metabolism_Homo sapiens_hsa002700.95261600
69Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.91578130
70Vitamin digestion and absorption_Homo sapiens_hsa049770.89959653
71Glutathione metabolism_Homo sapiens_hsa004800.89402218
72Arginine and proline metabolism_Homo sapiens_hsa003300.88794055
73Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.85486178
74Phototransduction_Homo sapiens_hsa047440.83335332
75Collecting duct acid secretion_Homo sapiens_hsa049660.82332922
76Lysosome_Homo sapiens_hsa041420.82164761
77Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.81406093
78Glycerolipid metabolism_Homo sapiens_hsa005610.80750014
79Oxidative phosphorylation_Homo sapiens_hsa001900.79418361
80Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.77503820
81Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.71772546
82Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.71540488
83SNARE interactions in vesicular transport_Homo sapiens_hsa041300.70785149
84Parkinsons disease_Homo sapiens_hsa050120.70169434
85Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.70113460
86Asthma_Homo sapiens_hsa053100.69423815
87Allograft rejection_Homo sapiens_hsa053300.66322248
88Autoimmune thyroid disease_Homo sapiens_hsa053200.63857531
89Steroid biosynthesis_Homo sapiens_hsa001000.62305007
90Regulation of autophagy_Homo sapiens_hsa041400.61495329
91Galactose metabolism_Homo sapiens_hsa000520.59237586
92Graft-versus-host disease_Homo sapiens_hsa053320.57804458
93Metabolic pathways_Homo sapiens_hsa011000.57704577
94Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.52032772
95Rheumatoid arthritis_Homo sapiens_hsa053230.49286240
96Sphingolipid metabolism_Homo sapiens_hsa006000.49009904
97Alzheimers disease_Homo sapiens_hsa050100.47544937
98Ether lipid metabolism_Homo sapiens_hsa005650.47186661
99RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.45471111
100Type I diabetes mellitus_Homo sapiens_hsa049400.45041087
101Fructose and mannose metabolism_Homo sapiens_hsa000510.44916790
102Fanconi anemia pathway_Homo sapiens_hsa034600.43667930
103Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.42048182
104Systemic lupus erythematosus_Homo sapiens_hsa053220.41103019
105Adipocytokine signaling pathway_Homo sapiens_hsa049200.39734315
106Insulin resistance_Homo sapiens_hsa049310.38285477
107Huntingtons disease_Homo sapiens_hsa050160.34687613
108Fatty acid biosynthesis_Homo sapiens_hsa000610.33753381
109Vitamin B6 metabolism_Homo sapiens_hsa007500.31544686
110Bladder cancer_Homo sapiens_hsa052190.30247663
111alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.28980175
112Linoleic acid metabolism_Homo sapiens_hsa005910.19589725
113Renin-angiotensin system_Homo sapiens_hsa046140.18875345
114Protein export_Homo sapiens_hsa030600.16714072
115Carbohydrate digestion and absorption_Homo sapiens_hsa049730.15913779
116AMPK signaling pathway_Homo sapiens_hsa041520.15290191
117Glucagon signaling pathway_Homo sapiens_hsa049220.13965830
118Cardiac muscle contraction_Homo sapiens_hsa042600.10888722
119Pyrimidine metabolism_Homo sapiens_hsa002400.09220401
120Arachidonic acid metabolism_Homo sapiens_hsa005900.06934114
121Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.06422437
122Other glycan degradation_Homo sapiens_hsa005110.05148225
123Insulin signaling pathway_Homo sapiens_hsa049100.04513190
124Glycerophospholipid metabolism_Homo sapiens_hsa005640.01846549
125Mineral absorption_Homo sapiens_hsa049780.01351829
126Acute myeloid leukemia_Homo sapiens_hsa052210.01149883
127Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141-0.0114274
128Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512-0.0084536
129Prion diseases_Homo sapiens_hsa05020-0.0073051
130Protein digestion and absorption_Homo sapiens_hsa04974-0.0002888

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