OCIAD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle maturation (GO:0016188)6.20737184
2regulation of short-term neuronal synaptic plasticity (GO:0048172)5.73184884
3positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.52635882
4synaptic vesicle exocytosis (GO:0016079)5.44118505
5synaptic vesicle docking involved in exocytosis (GO:0016081)5.16720442
6glutamate secretion (GO:0014047)5.16108700
7regulation of synaptic vesicle exocytosis (GO:2000300)5.10607867
8neuronal action potential propagation (GO:0019227)5.05103117
9locomotory exploration behavior (GO:0035641)4.86650400
10mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.68830680
11regulation of synaptic vesicle transport (GO:1902803)4.63279335
12positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.52696417
13neurotransmitter secretion (GO:0007269)4.50381036
14neuromuscular process controlling posture (GO:0050884)4.48147086
15positive regulation of synaptic transmission, dopaminergic (GO:0032226)4.41745897
16cell communication by electrical coupling involved in cardiac conduction (GO:0086064)4.39036133
17vocalization behavior (GO:0071625)4.17083776
18sodium ion export (GO:0071436)4.15688226
19activation of protein kinase A activity (GO:0034199)4.13591339
20mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.13186921
21membrane depolarization during cardiac muscle cell action potential (GO:0086012)4.07468062
22cell communication by electrical coupling (GO:0010644)4.04097559
23regulation of glutamate receptor signaling pathway (GO:1900449)4.03724071
24regulation of synapse structural plasticity (GO:0051823)4.01673123
25cellular potassium ion homeostasis (GO:0030007)3.99140193
26regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.98203057
27regulation of long-term neuronal synaptic plasticity (GO:0048169)3.93779048
28regulation of neuronal synaptic plasticity (GO:0048168)3.90348216
29energy coupled proton transport, down electrochemical gradient (GO:0015985)3.72820993
30ATP synthesis coupled proton transport (GO:0015986)3.72820993
31exploration behavior (GO:0035640)3.71737774
32gamma-aminobutyric acid transport (GO:0015812)3.70781242
33protein localization to synapse (GO:0035418)3.69146630
34regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.69009085
35respiratory electron transport chain (GO:0022904)3.64074218
36neurotransmitter-gated ion channel clustering (GO:0072578)3.61756933
37regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.58882895
38proline transport (GO:0015824)3.57422148
39electron transport chain (GO:0022900)3.56015130
40cerebellar Purkinje cell layer development (GO:0021680)3.55781635
41COPI coating of Golgi vesicle (GO:0048205)3.48855301
42Golgi transport vesicle coating (GO:0048200)3.48855301
43neurotransmitter transport (GO:0006836)3.46440949
44synaptic transmission, glutamatergic (GO:0035249)3.42271235
45cullin deneddylation (GO:0010388)3.41327156
46neuron-neuron synaptic transmission (GO:0007270)3.39239831
47ionotropic glutamate receptor signaling pathway (GO:0035235)3.37466788
48positive regulation of synapse maturation (GO:0090129)3.37012953
49positive regulation of membrane potential (GO:0045838)3.34132173
50response to pheromone (GO:0019236)3.32509044
51chaperone-mediated protein transport (GO:0072321)3.32492174
52NADH metabolic process (GO:0006734)3.28370219
53cerebellar Purkinje cell differentiation (GO:0021702)3.27586868
54regulation of neurotransmitter levels (GO:0001505)3.27271923
55layer formation in cerebral cortex (GO:0021819)3.26787856
56protein deneddylation (GO:0000338)3.26139765
57long-term memory (GO:0007616)3.20816762
58positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.15592711
59regulation of synaptic plasticity (GO:0048167)3.13481232
60detection of calcium ion (GO:0005513)3.12360857
61succinate metabolic process (GO:0006105)3.11515745
62positive regulation of synaptic transmission, GABAergic (GO:0032230)3.09977037
63membrane depolarization during action potential (GO:0086010)3.07285468
64regulation of synaptic transmission, dopaminergic (GO:0032225)3.06412757
65neuromuscular process controlling balance (GO:0050885)3.04231331
66cellular sodium ion homeostasis (GO:0006883)3.03973536
67regulation of excitatory postsynaptic membrane potential (GO:0060079)3.02504021
68long-term synaptic potentiation (GO:0060291)3.01191767
69regulation of neurotransmitter secretion (GO:0046928)3.00745791
70presynaptic membrane assembly (GO:0097105)3.00654923
71glycine transport (GO:0015816)2.98782050
72tricarboxylic acid cycle (GO:0006099)2.97765806
73negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.96056737
74vesicle transport along microtubule (GO:0047496)2.95601210
75regulation of sodium ion transmembrane transporter activity (GO:2000649)2.94281586
76potassium ion import (GO:0010107)2.92755245
77regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.92083833
78regulation of postsynaptic membrane potential (GO:0060078)2.91809512
79cell communication involved in cardiac conduction (GO:0086065)2.91732357
80ATP hydrolysis coupled proton transport (GO:0015991)2.90962976
81energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.90962976
82glutamate receptor signaling pathway (GO:0007215)2.90866166
83negative regulation of microtubule polymerization (GO:0031115)2.90799652
84presynaptic membrane organization (GO:0097090)2.90287229
85negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.88935277
86oxaloacetate metabolic process (GO:0006107)2.87961493
87neuron cell-cell adhesion (GO:0007158)2.85457373
88negative regulation of synaptic transmission, GABAergic (GO:0032229)2.85331246
89gamma-aminobutyric acid signaling pathway (GO:0007214)2.85185230
90regulation of neurotransmitter transport (GO:0051588)2.85182931
91protein neddylation (GO:0045116)2.84028876
92positive regulation of potassium ion transmembrane transport (GO:1901381)2.83704716
93regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.82094350
94positive regulation of neurotransmitter transport (GO:0051590)2.81652451
95membrane repolarization (GO:0086009)2.81156833
96neuromuscular process (GO:0050905)2.79829500
97innervation (GO:0060384)2.78717369
98establishment of integrated proviral latency (GO:0075713)2.78614455
99oxidative phosphorylation (GO:0006119)2.78099653
100regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)2.77327253
101positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.75952008
102response to auditory stimulus (GO:0010996)2.75576739
103regulation of vesicle fusion (GO:0031338)2.75541155
104protein maturation by protein folding (GO:0022417)2.74905010
105regulation of synaptic transmission, glutamatergic (GO:0051966)2.74902301
106positive regulation of synaptic transmission (GO:0050806)2.73673137
107G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.72827338
108synaptic transmission (GO:0007268)2.72736009
109axon cargo transport (GO:0008088)2.72462591
110negative regulation of cytosolic calcium ion concentration (GO:0051481)2.72313742
111proteasome assembly (GO:0043248)2.70601813
112organelle transport along microtubule (GO:0072384)2.68854883
113regulation of synaptic transmission (GO:0050804)2.68561896
114membrane hyperpolarization (GO:0060081)2.68225310
115signal release (GO:0023061)2.67636118
116protein complex biogenesis (GO:0070271)2.66052751
117water-soluble vitamin biosynthetic process (GO:0042364)2.64992921
118protein-cofactor linkage (GO:0018065)2.64800259
119establishment of protein localization to mitochondrial membrane (GO:0090151)2.64371668
120L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.62388601
121DNA damage response, detection of DNA damage (GO:0042769)2.60901942
122organelle disassembly (GO:1903008)2.58346822
123hydrogen ion transmembrane transport (GO:1902600)2.56618280
124ribonucleoprotein complex disassembly (GO:0032988)2.54940782
125mitochondrial respiratory chain complex assembly (GO:0033108)2.52030918
126aldehyde catabolic process (GO:0046185)2.51236036
127ATP biosynthetic process (GO:0006754)2.45382040
128mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.45338331
129mitochondrial respiratory chain complex I assembly (GO:0032981)2.45338331
130NADH dehydrogenase complex assembly (GO:0010257)2.45338331
131L-methionine biosynthetic process (GO:0071265)2.44108206
132amino acid salvage (GO:0043102)2.44108206
133L-methionine salvage (GO:0071267)2.44108206
134postsynaptic membrane organization (GO:0001941)2.43208723
135pyrimidine nucleobase catabolic process (GO:0006208)2.41836056
136regulation of mitochondrial translation (GO:0070129)2.40029530
137respiratory chain complex IV assembly (GO:0008535)2.39919699
138positive regulation of mitochondrial fission (GO:0090141)2.36047486
139neurofilament cytoskeleton organization (GO:0060052)2.34151902
140regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)2.33656992
141protein localization to cilium (GO:0061512)2.32569859
142regulation of cell communication by electrical coupling (GO:0010649)2.31432366
143protein targeting to mitochondrion (GO:0006626)2.31152481
144neurotransmitter uptake (GO:0001504)2.30290608
145proton transport (GO:0015992)2.29806593
146short-term memory (GO:0007614)2.27972030
147hydrogen transport (GO:0006818)2.26785360
148regulation of cofactor metabolic process (GO:0051193)2.25359426
149regulation of coenzyme metabolic process (GO:0051196)2.25359426
150establishment of viral latency (GO:0019043)2.25138178
151auditory behavior (GO:0031223)2.24038724
152protein localization to mitochondrion (GO:0070585)2.23755281
153cerebellar granule cell differentiation (GO:0021707)2.21701520
154establishment of protein localization to mitochondrion (GO:0072655)2.21334838
155substantia nigra development (GO:0021762)2.20965314
156nucleobase catabolic process (GO:0046113)2.20188359
157peptidyl-cysteine modification (GO:0018198)2.19717458
158intracellular protein transmembrane import (GO:0044743)2.18836647
159purine nucleoside triphosphate biosynthetic process (GO:0009145)2.17683218
160regulation of acyl-CoA biosynthetic process (GO:0050812)2.16885438
161G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.16339539
162nonmotile primary cilium assembly (GO:0035058)2.14614231
163purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.13884140

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.61395941
2E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.82999688
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.43137291
4RARB_27405468_Chip-Seq_BRAIN_Mouse3.35359459
5RBPJ_22232070_ChIP-Seq_NCS_Mouse3.15274345
6REST_21632747_ChIP-Seq_MESCs_Mouse3.11230319
7REST_18959480_ChIP-ChIP_MESCs_Mouse3.10418869
8ESRRB_18555785_ChIP-Seq_MESCs_Mouse2.99421280
9SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.97650726
10* GABP_17652178_ChIP-ChIP_JURKAT_Human2.97383551
11SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.92964527
12MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.89932885
13CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.69093351
14SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.63072390
15* EST1_17652178_ChIP-ChIP_JURKAT_Human2.61415458
16GBX2_23144817_ChIP-Seq_PC3_Human2.54660592
17MTF2_20144788_ChIP-Seq_MESCs_Mouse2.52732243
18JARID2_20064375_ChIP-Seq_MESCs_Mouse2.51004452
19NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.49383106
20DROSHA_22980978_ChIP-Seq_HELA_Human2.49041815
21JARID2_20075857_ChIP-Seq_MESCs_Mouse2.45143592
22RNF2_18974828_ChIP-Seq_MESCs_Mouse2.42428434
23EZH2_18974828_ChIP-Seq_MESCs_Mouse2.42428434
24SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.28935154
25HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.28782047
26FUS_26573619_Chip-Seq_HEK293_Human2.27005807
27CREB1_15753290_ChIP-ChIP_HEK293T_Human2.26954768
28SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.25537574
29IKZF1_21737484_ChIP-ChIP_HCT116_Human2.23702214
30* POU3F2_20337985_ChIP-ChIP_501MEL_Human2.21269098
31EZH2_27294783_Chip-Seq_ESCs_Mouse2.10896938
32EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.07959688
33SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.07265184
34SUZ12_27294783_Chip-Seq_ESCs_Mouse2.06068044
35DNAJC2_21179169_ChIP-ChIP_NT2_Human2.02948202
36ELK1_19687146_ChIP-ChIP_HELA_Human2.02126108
37NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.99593908
38ETS1_20019798_ChIP-Seq_JURKAT_Human1.97835858
39ZFP57_27257070_Chip-Seq_ESCs_Mouse1.96872997
40ERG_21242973_ChIP-ChIP_JURKAT_Human1.95645504
41CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.93387842
42MYC_18555785_ChIP-Seq_MESCs_Mouse1.88409946
43EZH2_27304074_Chip-Seq_ESCs_Mouse1.83892540
44EWS_26573619_Chip-Seq_HEK293_Human1.78215639
45IGF1R_20145208_ChIP-Seq_DFB_Human1.77646842
46ZFP281_18757296_ChIP-ChIP_E14_Mouse1.76962802
47PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.75269036
48CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.73904279
49* JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.73111962
50* ZNF274_21170338_ChIP-Seq_K562_Hela1.69623015
51EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.68456842
52RNF2_27304074_Chip-Seq_ESCs_Mouse1.68255307
53NR3C1_23031785_ChIP-Seq_PC12_Mouse1.68181727
54SALL1_21062744_ChIP-ChIP_HESCs_Human1.67425150
55EED_16625203_ChIP-ChIP_MESCs_Mouse1.64071422
56HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.53133627
57RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.52612593
58MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.49677777
59P300_19829295_ChIP-Seq_ESCs_Human1.49094586
60FLI1_27457419_Chip-Seq_LIVER_Mouse1.49041799
61ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.48295246
62* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.47746331
63VDR_22108803_ChIP-Seq_LS180_Human1.46940472
64FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.45854430
65SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.45445200
66VDR_23849224_ChIP-Seq_CD4+_Human1.42606052
67DCP1A_22483619_ChIP-Seq_HELA_Human1.41212189
68BMI1_23680149_ChIP-Seq_NPCS_Mouse1.36438695
69MYC_18940864_ChIP-ChIP_HL60_Human1.36339622
70RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.33814915
71* CTBP2_25329375_ChIP-Seq_LNCAP_Human1.33106351
72LXR_22292898_ChIP-Seq_THP-1_Human1.30900962
73PADI4_21655091_ChIP-ChIP_MCF-7_Human1.30654680
74RNF2_27304074_Chip-Seq_NSC_Mouse1.29811718
75PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.29809635
76YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.27717819
77TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.27434354
78TET1_21490601_ChIP-Seq_MESCs_Mouse1.25495793
79OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.25362323
80* SOX2_21211035_ChIP-Seq_LN229_Gbm1.23173958
81TTF2_22483619_ChIP-Seq_HELA_Human1.20415043
82WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.20152159
83GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.18836434
84TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.18815501
85* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.17792866
86ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.17735112
87KDM2B_26808549_Chip-Seq_K562_Human1.16749445
88SMAD4_21799915_ChIP-Seq_A2780_Human1.15939057
89SOX2_16153702_ChIP-ChIP_HESCs_Human1.15846195
90SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.15173333
91CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.13426049
92PCGF2_27294783_Chip-Seq_ESCs_Mouse1.13035639
93TOP2B_26459242_ChIP-Seq_MCF-7_Human1.12385265
94GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12260882
95PIAS1_25552417_ChIP-Seq_VCAP_Human1.12256224
96MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.12036010
97SRF_21415370_ChIP-Seq_HL-1_Mouse1.11350887
98AR_19668381_ChIP-Seq_PC3_Human1.11240943
99* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.11055741
100* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.10453405
101AR_21572438_ChIP-Seq_LNCaP_Human1.10021046
102POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.09418019
103* SMC4_20622854_ChIP-Seq_HELA_Human1.08861063
104DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.07682422
105XRN2_22483619_ChIP-Seq_HELA_Human1.07654931
106* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.06370090
107HTT_18923047_ChIP-ChIP_STHdh_Human1.06232765
108SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.06022769
109* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.05846211
110RING1B_27294783_Chip-Seq_ESCs_Mouse1.05513258
111MYC_19079543_ChIP-ChIP_MESCs_Mouse1.05163610
112POU5F1_16153702_ChIP-ChIP_HESCs_Human1.05123205
113MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.04716637
114CTCF_27219007_Chip-Seq_Bcells_Human1.04491810
115NANOG_18555785_Chip-Seq_ESCs_Mouse1.03500266
116ZNF263_19887448_ChIP-Seq_K562_Human1.02866340
117AR_25329375_ChIP-Seq_VCAP_Human1.02203863
118POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.02060343
119CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.01269723
120SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.99822621
121FOXP3_21729870_ChIP-Seq_TREG_Human0.99024351
122CBX2_27304074_Chip-Seq_ESCs_Mouse0.98251441
123* CTBP1_25329375_ChIP-Seq_LNCAP_Human0.98069335
124WT1_25993318_ChIP-Seq_PODOCYTE_Human0.97470044
125TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.97375771
126GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.97110405
127GABP_19822575_ChIP-Seq_HepG2_Human0.96706357
128SMAD3_21741376_ChIP-Seq_EPCs_Human0.95967521
129* MYCN_18555785_ChIP-Seq_MESCs_Mouse0.95930322
130* OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.95834779
131TAF15_26573619_Chip-Seq_HEK293_Human0.95782859
132KLF5_20875108_ChIP-Seq_MESCs_Mouse0.95285164
133NANOG_16153702_ChIP-ChIP_HESCs_Human0.94009919
134* MYC_18358816_ChIP-ChIP_MESCs_Mouse0.93647977
135TAL1_26923725_Chip-Seq_HPCs_Mouse0.93445732
136GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.93067395
137ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.91899862
138UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.90711378
139KLF4_19829295_ChIP-Seq_ESCs_Human0.90654858
140* JUN_21703547_ChIP-Seq_K562_Human0.90590735
141P53_22387025_ChIP-Seq_ESCs_Mouse0.90054708
142AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.89615488
143CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.89134381
144EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.89126606
145ELF1_20517297_ChIP-Seq_JURKAT_Human0.88052358
146THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.87429763
147PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.87414644
148KDM2B_26808549_Chip-Seq_SUP-B15_Human0.85827707
149* SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.85395867
150PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.84808051
151TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.84223624
152SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.84021127
153CTCF_18555785_ChIP-Seq_MESCs_Mouse0.82845985
154RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.81161389
155YAP1_20516196_ChIP-Seq_MESCs_Mouse0.80570373
156* STAT3_23295773_ChIP-Seq_U87_Human0.80034897
157SRY_22984422_ChIP-ChIP_TESTIS_Rat0.79453534
158P68_20966046_ChIP-Seq_HELA_Human0.78047244
159SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.77892043
160TET1_21451524_ChIP-Seq_MESCs_Mouse0.77180399
161SMAD4_21741376_ChIP-Seq_HESCs_Human0.77173228
162SMAD4_21741376_ChIP-Seq_ESCs_Human0.77001694
163REST_19997604_ChIP-ChIP_NEURONS_Mouse0.76578114
164SOX2_21211035_ChIP-Seq_LN229_Human0.75616995
165* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.75291872
166CREB1_26743006_Chip-Seq_LNCaP_Human0.74456934
167* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.74358838
168SMAD3_21741376_ChIP-Seq_ESCs_Human0.74200419
169MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.74182532
170SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.73961101
171TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.72922686
172MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.72513442
173OCT4_19829295_ChIP-Seq_ESCs_Human0.72347295
174PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.72226359
175THAP11_20581084_ChIP-Seq_MESCs_Mouse0.72041263

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.16327851
2MP0003635_abnormal_synaptic_transmissio3.84771647
3MP0003880_abnormal_central_pattern3.40625552
4MP0004270_analgesia3.40478032
5MP0002064_seizures2.93779661
6MP0002063_abnormal_learning/memory/cond2.92149524
7MP0009745_abnormal_behavioral_response2.90425520
8MP0009780_abnormal_chondrocyte_physiolo2.89625744
9MP0002909_abnormal_adrenal_gland2.82183974
10MP0009046_muscle_twitch2.79511132
11MP0001968_abnormal_touch/_nociception2.75765828
12MP0002822_catalepsy2.53402018
13MP0002837_dystrophic_cardiac_calcinosis2.47984062
14MP0002272_abnormal_nervous_system2.45281480
15MP0002572_abnormal_emotion/affect_behav2.37469360
16MP0002734_abnormal_mechanical_nocicepti2.33986595
17MP0003329_amyloid_beta_deposits2.30532222
18MP0002736_abnormal_nociception_after2.14693339
19MP0000013_abnormal_adipose_tissue2.13921202
20MP0001501_abnormal_sleep_pattern2.13099340
21MP0002733_abnormal_thermal_nociception2.02963404
22MP0003941_abnormal_skin_development2.00071882
23MP0008877_abnormal_DNA_methylation1.96780132
24MP0000751_myopathy1.93189912
25MP0008569_lethality_at_weaning1.89430775
26MP0003183_abnormal_peptide_metabolism1.87969762
27MP0001970_abnormal_pain_threshold1.85067619
28MP0001188_hyperpigmentation1.83579514
29MP0002735_abnormal_chemical_nociception1.83147789
30MP0005423_abnormal_somatic_nervous1.77528048
31MP0005646_abnormal_pituitary_gland1.77456179
32MP0004858_abnormal_nervous_system1.77003102
33MP0002067_abnormal_sensory_capabilities1.75721685
34MP0004811_abnormal_neuron_physiology1.75398981
35MP0001486_abnormal_startle_reflex1.73273774
36MP0004043_abnormal_pH_regulation1.63464043
37MP0003122_maternal_imprinting1.63106988
38MP0003879_abnormal_hair_cell1.62477598
39MP0004924_abnormal_behavior1.58339711
40MP0005386_behavior/neurological_phenoty1.58339711
41MP0001440_abnormal_grooming_behavior1.55506255
42MP0002184_abnormal_innervation1.52589146
43MP0003283_abnormal_digestive_organ1.48182036
44MP0004215_abnormal_myocardial_fiber1.47647189
45MP0004145_abnormal_muscle_electrophysio1.45155764
46MP0005187_abnormal_penis_morphology1.41690720
47MP0000955_abnormal_spinal_cord1.41535659
48MP0004233_abnormal_muscle_weight1.41350368
49MP0004147_increased_porphyrin_level1.40320718
50MP0002557_abnormal_social/conspecific_i1.38975265
51MP0006276_abnormal_autonomic_nervous1.38715580
52MP0006072_abnormal_retinal_apoptosis1.38635495
53MP0003121_genomic_imprinting1.36825531
54MP0008961_abnormal_basal_metabolism1.34755073
55MP0008058_abnormal_DNA_repair1.34544928
56MP0004142_abnormal_muscle_tone1.32790061
57MP0002066_abnormal_motor_capabilities/c1.29757358
58MP0003633_abnormal_nervous_system1.28458151
59MP0001984_abnormal_olfaction1.25905441
60MP0003890_abnormal_embryonic-extraembry1.25286077
61MP0010386_abnormal_urinary_bladder1.24430645
62MP0003646_muscle_fatigue1.21167727
63MP0004084_abnormal_cardiac_muscle1.18570848
64MP0004036_abnormal_muscle_relaxation1.18532372
65MP0001529_abnormal_vocalization1.17915172
66MP0009697_abnormal_copulation1.17123443
67MP0002882_abnormal_neuron_morphology1.16419317
68MP0003136_yellow_coat_color1.16043801
69MP0000604_amyloidosis1.15524370
70MP0004130_abnormal_muscle_cell1.14646698
71MP0005645_abnormal_hypothalamus_physiol1.14362637
72MP0000631_abnormal_neuroendocrine_gland1.13116167
73MP0000566_synostosis1.12926497
74MP0003172_abnormal_lysosome_physiology1.10961187
75MP0003186_abnormal_redox_activity1.09158049
76MP0000747_muscle_weakness1.08792604
77MP0005535_abnormal_body_temperature1.06847158
78MP0005394_taste/olfaction_phenotype1.06242240
79MP0005499_abnormal_olfactory_system1.06242240
80MP0008789_abnormal_olfactory_epithelium1.04081316
81MP0001502_abnormal_circadian_rhythm1.03827791
82MP0004085_abnormal_heartbeat1.01968823
83MP0005551_abnormal_eye_electrophysiolog1.00004390
84MP0008995_early_reproductive_senescence0.99857406
85MP0001177_atelectasis0.99174749
86MP0005253_abnormal_eye_physiology0.98805424
87MP0001944_abnormal_pancreas_morphology0.96376039
88MP0003631_nervous_system_phenotype0.96256913
89MP0002269_muscular_atrophy0.96050107
90MP0002229_neurodegeneration0.95753172
91MP0006036_abnormal_mitochondrial_physio0.95697687
92MP0004133_heterotaxia0.94834614
93MP0002078_abnormal_glucose_homeostasis0.93016076
94MP0002069_abnormal_eating/drinking_beha0.92955697
95MP0004885_abnormal_endolymph0.91807774
96MP0001485_abnormal_pinna_reflex0.91472346
97MP0004742_abnormal_vestibular_system0.90256648
98MP0003137_abnormal_impulse_conducting0.89593216
99MP0001905_abnormal_dopamine_level0.85990889
100MP0000749_muscle_degeneration0.85782493
101MP0002102_abnormal_ear_morphology0.85764923
102MP0002638_abnormal_pupillary_reflex0.85225964
103MP0008874_decreased_physiological_sensi0.84171107
104MP0003787_abnormal_imprinting0.84139824
105MP0000778_abnormal_nervous_system0.83118385
106MP0003075_altered_response_to0.82800717
107MP0009379_abnormal_foot_pigmentation0.82389476
108MP0008872_abnormal_physiological_respon0.82206252
109MP0002876_abnormal_thyroid_physiology0.81324987
110MP0004957_abnormal_blastocyst_morpholog0.80227055
111MP0006035_abnormal_mitochondrial_morpho0.79665440
112MP0002752_abnormal_somatic_nervous0.79539635
113MP0002693_abnormal_pancreas_physiology0.79530345
114MP0002152_abnormal_brain_morphology0.77698538
115MP0002234_abnormal_pharynx_morphology0.77459699
116MP0003786_premature_aging0.77171370
117MP0000647_abnormal_sebaceous_gland0.77097632
118MP0003119_abnormal_digestive_system0.76662386
119MP0005379_endocrine/exocrine_gland_phen0.75196466
120MP0001299_abnormal_eye_distance/0.74579579
121MP0000003_abnormal_adipose_tissue0.74546246
122MP0008932_abnormal_embryonic_tissue0.73335138
123MP0002938_white_spotting0.72589616
124MP0003634_abnormal_glial_cell0.71318764
125MP0003123_paternal_imprinting0.71167826
126MP0005330_cardiomyopathy0.70903305
127MP0002233_abnormal_nose_morphology0.70122302
128MP0001765_abnormal_ion_homeostasis0.69646714
129MP0005620_abnormal_muscle_contractility0.68953850
130MP0001963_abnormal_hearing_physiology0.68912084
131MP0001664_abnormal_digestion0.66524404
132MP0003953_abnormal_hormone_level0.65682059
133MP0002090_abnormal_vision0.64480386
134MP0002653_abnormal_ependyma_morphology0.64281426
135MP0002972_abnormal_cardiac_muscle0.63881909
136MP0000230_abnormal_systemic_arterial0.63407339

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)5.89946577
2Myokymia (HP:0002411)5.69960095
3Visual hallucinations (HP:0002367)4.88028715
4Focal seizures (HP:0007359)4.17729067
5Atonic seizures (HP:0010819)4.12168923
6Acute necrotizing encephalopathy (HP:0006965)3.95356870
7Pheochromocytoma (HP:0002666)3.78412349
8Epileptic encephalopathy (HP:0200134)3.63362033
9Progressive macrocephaly (HP:0004481)3.62241902
10Absence seizures (HP:0002121)3.55317935
11Abnormal mitochondria in muscle tissue (HP:0008316)3.54221997
12Depression (HP:0000716)3.53290935
13Neuroendocrine neoplasm (HP:0100634)3.52903788
14Acute encephalopathy (HP:0006846)3.43978836
15Generalized tonic-clonic seizures (HP:0002069)3.19205113
16Ankle clonus (HP:0011448)3.11171900
17Febrile seizures (HP:0002373)3.07329605
18Papilledema (HP:0001085)3.02642013
19Mitochondrial inheritance (HP:0001427)3.02406305
20Anxiety (HP:0000739)3.02155312
21Impaired vibration sensation in the lower limbs (HP:0002166)3.00261379
22Ventricular fibrillation (HP:0001663)2.98458485
23Dialeptic seizures (HP:0011146)2.97161066
24Action tremor (HP:0002345)2.96801502
25Supranuclear gaze palsy (HP:0000605)2.95190566
26Poor eye contact (HP:0000817)2.91251293
27Gait imbalance (HP:0002141)2.87781253
28Progressive cerebellar ataxia (HP:0002073)2.87738070
29Abnormal eating behavior (HP:0100738)2.84313153
30Decreased activity of mitochondrial respiratory chain (HP:0008972)2.81734502
31Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.81734502
32Increased hepatocellular lipid droplets (HP:0006565)2.80630655
33Increased CSF lactate (HP:0002490)2.79674624
34Truncal ataxia (HP:0002078)2.76828873
35Abnormal social behavior (HP:0012433)2.74591019
36Impaired social interactions (HP:0000735)2.74591019
37Increased serum pyruvate (HP:0003542)2.73008259
38Abnormality of the lower motor neuron (HP:0002366)2.71134032
39Hepatocellular necrosis (HP:0001404)2.68274142
40Hepatic necrosis (HP:0002605)2.66115759
41Abnormality of the labia minora (HP:0012880)2.64790059
423-Methylglutaconic aciduria (HP:0003535)2.64734940
43Cerebral edema (HP:0002181)2.63780782
44Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.63638634
45Resting tremor (HP:0002322)2.62728686
46Neoplasm of the peripheral nervous system (HP:0100007)2.62530169
47Abnormality of glycolysis (HP:0004366)2.61045507
48Hypoglycemic coma (HP:0001325)2.60487707
49Torticollis (HP:0000473)2.57392100
50Medial flaring of the eyebrow (HP:0010747)2.57198817
51Focal dystonia (HP:0004373)2.54696148
52Congenital primary aphakia (HP:0007707)2.53428735
53Hyperinsulinemic hypoglycemia (HP:0000825)2.53375877
54Exercise-induced muscle cramps (HP:0003710)2.52607549
55Lipid accumulation in hepatocytes (HP:0006561)2.50523862
56Limb dystonia (HP:0002451)2.50001492
57Epileptiform EEG discharges (HP:0011182)2.45585441
58Postural instability (HP:0002172)2.45337410
59Cerebral hypomyelination (HP:0006808)2.43721280
60Agitation (HP:0000713)2.42140095
61Hemiplegia (HP:0002301)2.41574652
62Bradykinesia (HP:0002067)2.41261344
63Craniofacial dystonia (HP:0012179)2.40481444
64Degeneration of the lateral corticospinal tracts (HP:0002314)2.38482674
65Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.38482674
66Nephrogenic diabetes insipidus (HP:0009806)2.37418447
67EEG with generalized epileptiform discharges (HP:0011198)2.37173265
68Dysmetric saccades (HP:0000641)2.36902845
69Methylmalonic acidemia (HP:0002912)2.34087569
70Hypsarrhythmia (HP:0002521)2.32926692
71Bundle branch block (HP:0011710)2.32100097
72Dysdiadochokinesis (HP:0002075)2.32033636
73Mutism (HP:0002300)2.30137142
74Urinary urgency (HP:0000012)2.27674992
75Impaired smooth pursuit (HP:0007772)2.25056347
76Hypercortisolism (HP:0001578)2.23825730
77Dysmetria (HP:0001310)2.23769941
78Status epilepticus (HP:0002133)2.23001440
79Gaze-evoked nystagmus (HP:0000640)2.21038866
80Spastic gait (HP:0002064)2.18736045
81Polyphagia (HP:0002591)2.17785547
82Progressive inability to walk (HP:0002505)2.16395028
83Urinary bladder sphincter dysfunction (HP:0002839)2.14348137
84Spinal canal stenosis (HP:0003416)2.14264926
85Ketoacidosis (HP:0001993)2.13318059
86Abnormality of the corticospinal tract (HP:0002492)2.12742510
87Hypoglycemic seizures (HP:0002173)2.12323354
88Lactic acidosis (HP:0003128)2.11386912
89Oligomenorrhea (HP:0000876)2.11358404
90Neuronal loss in central nervous system (HP:0002529)2.10501755
91Ragged-red muscle fibers (HP:0003200)2.10062437
92Genital tract atresia (HP:0001827)2.09516212
93Impaired pain sensation (HP:0007328)2.08633878
94Abnormality of pain sensation (HP:0010832)2.08633878
95Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.08579648
96Abnormality of alanine metabolism (HP:0010916)2.08579648
97Hyperalaninemia (HP:0003348)2.08579648
98CNS hypomyelination (HP:0003429)2.08365621
99Scanning speech (HP:0002168)2.07393594
100Vaginal atresia (HP:0000148)2.06232605
101Leukodystrophy (HP:0002415)2.06125174
102Broad-based gait (HP:0002136)2.03101022
103Exercise-induced myalgia (HP:0003738)2.03012272
104Hyperventilation (HP:0002883)2.01434191
105Poor suck (HP:0002033)2.00799822
106Gout (HP:0001997)2.00312782
107Abnormal gallbladder physiology (HP:0012438)1.99222715
108Cholecystitis (HP:0001082)1.99222715
109Insomnia (HP:0100785)1.98944355
110Abnormal EKG (HP:0003115)1.98447813
111Megalencephaly (HP:0001355)1.98199212
112Myotonia (HP:0002486)1.97589889
113Delusions (HP:0000746)1.96611443
114Emotional lability (HP:0000712)1.96375834
115Psychosis (HP:0000709)1.96210790
116Hypothermia (HP:0002045)1.95630971
117Exercise intolerance (HP:0003546)1.95477115
118Rigidity (HP:0002063)1.94269689
119Abnormality of ocular smooth pursuit (HP:0000617)1.93259769
120Impaired vibratory sensation (HP:0002495)1.92951229
121Failure to thrive in infancy (HP:0001531)1.92325643
122Clonus (HP:0002169)1.92251508
123Increased intramyocellular lipid droplets (HP:0012240)1.92235752
124Postural tremor (HP:0002174)1.90724531
125Respiratory failure (HP:0002878)1.89696714
126Increased serum lactate (HP:0002151)1.89315857
127Abnormality of the anterior horn cell (HP:0006802)1.89033245
128Degeneration of anterior horn cells (HP:0002398)1.89033245
129Optic nerve hypoplasia (HP:0000609)1.88734661
130Growth hormone excess (HP:0000845)1.87145251
131Abnormality of binocular vision (HP:0011514)1.86860085
132Diplopia (HP:0000651)1.86860085
133Athetosis (HP:0002305)1.86548631
134Renal Fanconi syndrome (HP:0001994)1.85469934
135Optic disc pallor (HP:0000543)1.83458577
136Abnormality of serum amino acid levels (HP:0003112)1.82543431
137Intention tremor (HP:0002080)1.81580153
138Abnormality of methionine metabolism (HP:0010901)1.81473032
139Unsteady gait (HP:0002317)1.81455411
140Amblyopia (HP:0000646)1.80866913
141Type II lissencephaly (HP:0007260)1.80382029
142Tetraplegia (HP:0002445)1.80325973
143Sudden death (HP:0001699)1.79884156
144Gait ataxia (HP:0002066)1.79866797
145Global brain atrophy (HP:0002283)1.78826815
146Lower limb muscle weakness (HP:0007340)1.78552187
147Menstrual irregularities (HP:0000858)1.78367597
148Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.77900352
149Muscular hypotonia of the trunk (HP:0008936)1.76916876
150Myoglobinuria (HP:0002913)1.76633223
151Genetic anticipation (HP:0003743)1.76399332
152Mucopolysacchariduria (HP:0008155)1.76233126
153Specific learning disability (HP:0001328)1.75417806
154Postnatal microcephaly (HP:0005484)1.75069847
155Hyperglycinemia (HP:0002154)1.74771728
156Hyperglycinuria (HP:0003108)1.74307715
157Rimmed vacuoles (HP:0003805)1.73028820
158Cortical dysplasia (HP:0002539)1.72903609
159X-linked dominant inheritance (HP:0001423)1.72721219
160Lethargy (HP:0001254)1.71880948
161Microvesicular hepatic steatosis (HP:0001414)1.71666860
162Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.71230884
163CNS demyelination (HP:0007305)1.71224705
164Abnormality of vitamin B metabolism (HP:0004340)1.67834372
165Atrophy/Degeneration involving motor neurons (HP:0007373)1.67516839
166Abnormality of serine family amino acid metabolism (HP:0010894)1.65618739
167Abnormality of glycine metabolism (HP:0010895)1.65618739
168Abnormality of the vitamin B12 metabolism (HP:0004341)1.64708131
169Morphological abnormality of the pyramidal tract (HP:0002062)1.64599521

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK34.18739014
2MAP3K93.76117006
3MINK12.82875936
4MAP3K42.74461354
5MAP3K122.73016260
6EPHA42.67603122
7KSR22.52342098
8MAP2K72.42576006
9ARAF2.22485051
10CDK192.21563270
11CAMKK12.18324070
12BCR2.17897300
13DAPK22.14748223
14NTRK12.13567852
15MAP2K42.12768463
16PRKD32.12520627
17NEK12.05501860
18SRPK12.02993835
19DAPK12.02902579
20CAMKK22.01075718
21TNIK1.99970177
22MARK11.95177370
23TRIB31.90732397
24PAK61.89460953
25SCYL21.86513473
26ERBB31.74516715
27EIF2AK11.70403267
28MST41.69197524
29KSR11.67400332
30TRIM281.61464012
31PNCK1.61054124
32CSNK1G21.58572542
33NTRK21.55317794
34LMTK21.41409994
35CDK51.38520536
36CSNK1G31.35962763
37UHMK11.35868012
38PLK31.35476213
39PKN21.33817714
40PHKG11.32865916
41PHKG21.32865916
42MAP4K21.31518575
43MAP3K21.30460419
44DYRK21.29455749
45MKNK11.29132149
46STK161.28827486
47GRK51.24695267
48STK381.24222010
49PRKCG1.20646143
50RET1.20392581
51TTK1.20132230
52CSNK1G11.18718864
53CCNB11.16196029
54MKNK21.15970728
55PBK1.15696326
56BUB11.14822309
57PDK31.08405309
58PDK41.08405309
59CSNK1A1L1.08057160
60OXSR11.07909515
61PRKCH1.07672762
62PASK1.04242077
63PINK11.02922189
64MAP3K11.02591778
65TAOK11.01696304
66RAF11.01151837
67BRAF1.00283051
68EIF2AK30.98296968
69CDC70.98201329
70BMPR1B0.97382255
71CDK140.95116697
72CDK180.93484265
73FES0.90176120
74PRPF4B0.88803185
75CDK150.88061724
76BRSK10.87270336
77PLK20.86017486
78CAMK10.84766575
79VRK10.83389272
80PAK30.81404837
81VRK20.80574083
82ALK0.78705744
83NME10.78541464
84TESK10.78371866
85OBSCN0.77774811
86LATS20.77140990
87MAPKAPK30.77075954
88PRKCE0.76927398
89CAMK2A0.76844744
90CDK11A0.75667055
91CASK0.74772335
92STK38L0.72049216
93DAPK30.69517607
94CSNK1E0.67693457
95BCKDK0.67608659
96PDK10.67504856
97FER0.66821991
98RPS6KA40.66709832
99MAP3K130.65060383
100PLK10.63927947
101CAMK2B0.63109659
102PDPK10.62065243
103INSRR0.61824556
104MAPKAPK50.59437164
105TSSK60.58093009
106PLK40.56616192
107SGK4940.56274493
108SGK2230.56274493
109CAMK2D0.55781081
110LIMK10.53958359
111MAPK130.53855654
112CDK30.53854090
113MAP2K10.53482353
114STK390.51998040
115CAMK2G0.51919121
116MAP3K70.51822778
117MAP3K110.50037916
118SIK30.49660458
119FGFR20.48849708
120DYRK30.48206263
121LATS10.47886511
122WNK40.45514150
123PTK2B0.45253601
124HIPK20.44671215
125CDC42BPA0.44080877
126RIPK10.43503164
127STK110.42552357
128RIPK40.42494704
129PRKG10.41736206
130NUAK10.41319659
131PDGFRA0.40884457
132SGK30.40862516
133CSNK1A10.40752091
134PIM20.40701988
135TYRO30.40632976
136CSNK2A20.39423571
137PRKDC0.38258821
138WNK30.38070603
139TNK20.37843745
140PRKACA0.37680035
141RPS6KA30.37541383
142ZAK0.36927897
143PRKCZ0.36434595
144PRKACB0.36122613
145DYRK1A0.35778297
146FLT30.35555690
147MARK20.35443535
148RPS6KA20.34767508
149WNK10.33962908
150MAP2K60.32129582
151SGK20.31396862

Predicted pathways (KEGG)

RankGene SetZ-score
1Synaptic vesicle cycle_Homo sapiens_hsa047213.85882347
2Protein export_Homo sapiens_hsa030603.40981455
3Nicotine addiction_Homo sapiens_hsa050333.00632350
4Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.82922256
5Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.58686642
6GABAergic synapse_Homo sapiens_hsa047272.56888705
7Olfactory transduction_Homo sapiens_hsa047402.53636723
8Insulin secretion_Homo sapiens_hsa049112.39042183
9Circadian entrainment_Homo sapiens_hsa047132.37045773
10Long-term potentiation_Homo sapiens_hsa047202.33622152
11Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.26178754
12Morphine addiction_Homo sapiens_hsa050322.10837981
13Amphetamine addiction_Homo sapiens_hsa050312.09796647
14Dopaminergic synapse_Homo sapiens_hsa047282.05027816
15Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.02423536
16Proteasome_Homo sapiens_hsa030501.97091512
17Collecting duct acid secretion_Homo sapiens_hsa049661.96410516
18Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.94675431
19Glutamatergic synapse_Homo sapiens_hsa047241.90791216
20Huntingtons disease_Homo sapiens_hsa050161.90343724
21Vibrio cholerae infection_Homo sapiens_hsa051101.79297884
22Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.79257619
23Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.73940961
24Salivary secretion_Homo sapiens_hsa049701.67652892
25Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.67646736
26Fatty acid elongation_Homo sapiens_hsa000621.65329253
27Cholinergic synapse_Homo sapiens_hsa047251.61540115
282-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.61494241
29Ribosome_Homo sapiens_hsa030101.59632608
30Aldosterone synthesis and secretion_Homo sapiens_hsa049251.59331181
31Gastric acid secretion_Homo sapiens_hsa049711.58005926
32Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.56610798
33Taste transduction_Homo sapiens_hsa047421.55732451
34Cocaine addiction_Homo sapiens_hsa050301.46416396
35Nitrogen metabolism_Homo sapiens_hsa009101.41472670
36Oxytocin signaling pathway_Homo sapiens_hsa049211.29866998
37Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.28111861
38Long-term depression_Homo sapiens_hsa047301.25275304
39Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.25020476
40Cysteine and methionine metabolism_Homo sapiens_hsa002701.23882399
41Type II diabetes mellitus_Homo sapiens_hsa049301.23527559
42Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.22765450
43Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.22390382
44Renin secretion_Homo sapiens_hsa049241.21996936
45Basal transcription factors_Homo sapiens_hsa030221.19623469
46Calcium signaling pathway_Homo sapiens_hsa040201.19542809
47Serotonergic synapse_Homo sapiens_hsa047261.18456685
48Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.15121167
49Cardiac muscle contraction_Homo sapiens_hsa042601.14397761
50Gap junction_Homo sapiens_hsa045401.08143736
51GnRH signaling pathway_Homo sapiens_hsa049121.07673035
52Folate biosynthesis_Homo sapiens_hsa007901.05983952
53Vitamin B6 metabolism_Homo sapiens_hsa007501.05605076
54Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.05324258
55cAMP signaling pathway_Homo sapiens_hsa040241.02126593
56Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.00564587
57Estrogen signaling pathway_Homo sapiens_hsa049151.00045362
58RNA polymerase_Homo sapiens_hsa030200.97683102
59Mismatch repair_Homo sapiens_hsa034300.97377248
60Phototransduction_Homo sapiens_hsa047440.94767153
61Sulfur metabolism_Homo sapiens_hsa009200.94415135
62Peroxisome_Homo sapiens_hsa041460.91652173
63Spliceosome_Homo sapiens_hsa030400.91473624
64Maturity onset diabetes of the young_Homo sapiens_hsa049500.91164593
65Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.91139503
66cGMP-PKG signaling pathway_Homo sapiens_hsa040220.90593618
67Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.88167386
68RNA transport_Homo sapiens_hsa030130.87634294
69Carbohydrate digestion and absorption_Homo sapiens_hsa049730.87619806
70beta-Alanine metabolism_Homo sapiens_hsa004100.87348696
71Glucagon signaling pathway_Homo sapiens_hsa049220.87204255
72Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.86886168
73Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.86515323
74Oocyte meiosis_Homo sapiens_hsa041140.86364027
75Glioma_Homo sapiens_hsa052140.85808847
76RNA degradation_Homo sapiens_hsa030180.84904258
77Selenocompound metabolism_Homo sapiens_hsa004500.84702177
78Pancreatic secretion_Homo sapiens_hsa049720.84361110
79Arginine and proline metabolism_Homo sapiens_hsa003300.83393314
80Thyroid hormone synthesis_Homo sapiens_hsa049180.81816772
81Steroid biosynthesis_Homo sapiens_hsa001000.80176367
82Nucleotide excision repair_Homo sapiens_hsa034200.79975546
83Phosphatidylinositol signaling system_Homo sapiens_hsa040700.77377175
84Carbon metabolism_Homo sapiens_hsa012000.76251563
85Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.76109241
86One carbon pool by folate_Homo sapiens_hsa006700.75749420
87Dilated cardiomyopathy_Homo sapiens_hsa054140.73384220
88Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.73278489
89Fatty acid metabolism_Homo sapiens_hsa012120.72796112
90Insulin signaling pathway_Homo sapiens_hsa049100.72647891
91Pyruvate metabolism_Homo sapiens_hsa006200.70065429
92Type I diabetes mellitus_Homo sapiens_hsa049400.69444782
93Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.68440163
94Butanoate metabolism_Homo sapiens_hsa006500.67628112
95Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.66583421
96Metabolic pathways_Homo sapiens_hsa011000.65594768
97Vascular smooth muscle contraction_Homo sapiens_hsa042700.63941695
98Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.62889602
99Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.62871323
100Neurotrophin signaling pathway_Homo sapiens_hsa047220.62527867
101Melanogenesis_Homo sapiens_hsa049160.61710570
102Primary bile acid biosynthesis_Homo sapiens_hsa001200.60798183
103ErbB signaling pathway_Homo sapiens_hsa040120.60361201
104Oxidative phosphorylation_Homo sapiens_hsa001900.59407280
105N-Glycan biosynthesis_Homo sapiens_hsa005100.59147431
106Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.58639503
107Parkinsons disease_Homo sapiens_hsa050120.57661545
108Arginine biosynthesis_Homo sapiens_hsa002200.57204725
109Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.57169951
110Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.56786328
111Biosynthesis of amino acids_Homo sapiens_hsa012300.56509071
112Purine metabolism_Homo sapiens_hsa002300.56020191
113Caffeine metabolism_Homo sapiens_hsa002320.55259512
114Endocytosis_Homo sapiens_hsa041440.54880157
115Phenylalanine metabolism_Homo sapiens_hsa003600.54281651
116Pentose and glucuronate interconversions_Homo sapiens_hsa000400.53839378
117Bile secretion_Homo sapiens_hsa049760.53688926
118Fatty acid degradation_Homo sapiens_hsa000710.53677041
119mTOR signaling pathway_Homo sapiens_hsa041500.53014299
120Glutathione metabolism_Homo sapiens_hsa004800.52177561
121Lysosome_Homo sapiens_hsa041420.51610842
122Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.51343058
123Alzheimers disease_Homo sapiens_hsa050100.51053169
124Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.50705764
125Prion diseases_Homo sapiens_hsa050200.48523302
126Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.48279440
127Central carbon metabolism in cancer_Homo sapiens_hsa052300.47756917
128SNARE interactions in vesicular transport_Homo sapiens_hsa041300.47717988
129mRNA surveillance pathway_Homo sapiens_hsa030150.46685673
130Circadian rhythm_Homo sapiens_hsa047100.45695646
131Chemical carcinogenesis_Homo sapiens_hsa052040.45401648
132VEGF signaling pathway_Homo sapiens_hsa043700.44707098
133Retinol metabolism_Homo sapiens_hsa008300.44474990
134Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.43546668
135Phospholipase D signaling pathway_Homo sapiens_hsa040720.42268431
136Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.41647391
137Mineral absorption_Homo sapiens_hsa049780.40641043
138Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.39390249
139Thyroid hormone signaling pathway_Homo sapiens_hsa049190.38441242
140Regulation of autophagy_Homo sapiens_hsa041400.38222881
141Longevity regulating pathway - mammal_Homo sapiens_hsa042110.37617115
142Alcoholism_Homo sapiens_hsa050340.34250778
143Endometrial cancer_Homo sapiens_hsa052130.31508650
144Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.31173928
145MAPK signaling pathway_Homo sapiens_hsa040100.30134756
146Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.30035825
147AMPK signaling pathway_Homo sapiens_hsa041520.28708940
148Fructose and mannose metabolism_Homo sapiens_hsa000510.28567797
149Propanoate metabolism_Homo sapiens_hsa006400.28367646

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