ODF3L2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of skeletal muscle contraction (GO:0014819)9.93089232
2skeletal muscle contraction (GO:0003009)9.48156222
3fusion of sperm to egg plasma membrane (GO:0007342)9.44236047
4sperm capacitation (GO:0048240)9.37001727
5chromosome condensation (GO:0030261)9.04093473
6sarcoplasmic reticulum calcium ion transport (GO:0070296)9.03660056
7skeletal muscle adaptation (GO:0043501)8.88858373
8DNA packaging (GO:0006323)8.76300208
9actin-mediated cell contraction (GO:0070252)8.36586258
10spermatid nucleus differentiation (GO:0007289)8.14546499
11single strand break repair (GO:0000012)8.03787104
12spermatid development (GO:0007286)7.82918260
13multicellular organism reproduction (GO:0032504)7.51844883
14skeletal muscle fiber development (GO:0048741)7.45389948
15plasma membrane fusion (GO:0045026)7.11914600
16sperm-egg recognition (GO:0035036)7.07316031
17microtubule depolymerization (GO:0007019)7.04117466
18reproduction (GO:0000003)6.96625201
19response to pheromone (GO:0019236)6.96411710
20protein polyglutamylation (GO:0018095)6.92124921
21binding of sperm to zona pellucida (GO:0007339)6.63895511
22creatine metabolic process (GO:0006600)6.57364878
23rRNA methylation (GO:0031167)6.53989602
24sexual reproduction (GO:0019953)6.44799632
25glycogen catabolic process (GO:0005980)6.44540688
26protein targeting to Golgi (GO:0000042)6.42681264
27negative regulation of inclusion body assembly (GO:0090084)6.40649431
28myotube cell development (GO:0014904)6.22761721
29calcium ion-dependent exocytosis (GO:0017156)6.22148524
30phosphatidylethanolamine biosynthetic process (GO:0006646)6.21182176
31actin filament-based movement (GO:0030048)6.20710022
32microtubule severing (GO:0051013)6.18982084
33establishment of protein localization to Golgi (GO:0072600)6.08598041
34glucan catabolic process (GO:0009251)6.02509639
35positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)6.02442433
36microtubule polymerization or depolymerization (GO:0031109)5.99164457
37retrograde transport, vesicle recycling within Golgi (GO:0000301)5.98199441
38spermatogenesis (GO:0007283)5.88223582
39male gamete generation (GO:0048232)5.85918645
40cell-cell recognition (GO:0009988)5.74355253
41phosphatidylethanolamine metabolic process (GO:0046337)5.73909001
42plasma membrane repair (GO:0001778)5.66039016
43cellular polysaccharide catabolic process (GO:0044247)5.58239822
44axonemal dynein complex assembly (GO:0070286)5.55903733
45skeletal muscle tissue regeneration (GO:0043403)5.48134078
46regulation of cilium movement (GO:0003352)5.47853965
47response to stimulus involved in regulation of muscle adaptation (GO:0014874)5.47294647
48rRNA modification (GO:0000154)5.45746982
49gamete generation (GO:0007276)5.39387207
50striated muscle contraction (GO:0006941)5.38553607
51polysaccharide catabolic process (GO:0000272)5.26423904
52response to muscle activity (GO:0014850)5.21797425
53striated muscle atrophy (GO:0014891)5.18845428
54regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)5.17753532
55cellular ketone body metabolic process (GO:0046950)5.14706819
56sarcomere organization (GO:0045214)5.11580063
57centriole replication (GO:0007099)5.09245658
58single fertilization (GO:0007338)5.07484139
59regulation of cell communication by electrical coupling (GO:0010649)5.03095191
60purine nucleotide salvage (GO:0032261)5.00275149
61regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)4.99923542
62glycogen biosynthetic process (GO:0005978)4.92458350
63glucan biosynthetic process (GO:0009250)4.92458350
64carnitine shuttle (GO:0006853)4.80115687
65cartilage development involved in endochondral bone morphogenesis (GO:0060351)4.79310883
66myofibril assembly (GO:0030239)4.78565256
67regulation of inclusion body assembly (GO:0090083)4.74676021
68positive regulation of mitochondrial calcium ion concentration (GO:0051561)4.74524529
69muscle contraction (GO:0006936)4.63962148
70neuronal action potential propagation (GO:0019227)4.62551332
71regulation of transcription involved in cell fate commitment (GO:0060850)4.60962734
72response to gravity (GO:0009629)4.57500778
73germ cell development (GO:0007281)4.56820419
74protein localization to Golgi apparatus (GO:0034067)4.55783846
75ketone body metabolic process (GO:1902224)4.51611017
76motile cilium assembly (GO:0044458)4.49857065
77IMP metabolic process (GO:0046040)4.48001919
78RNA destabilization (GO:0050779)4.46710443
79muscle atrophy (GO:0014889)4.45778915
80striated muscle adaptation (GO:0014888)4.44942153
81centriole assembly (GO:0098534)4.43103436
82response to inactivity (GO:0014854)4.40377900
83cell wall macromolecule catabolic process (GO:0016998)4.38894741
84fertilization (GO:0009566)4.38216057
85regulation of Rab GTPase activity (GO:0032313)4.35702937
86positive regulation of Rab GTPase activity (GO:0032851)4.35702937
87cellular process involved in reproduction in multicellular organism (GO:0022412)4.34530247
88glycogen metabolic process (GO:0005977)4.32222315
89multicellular organismal reproductive process (GO:0048609)4.30049557
90glucan metabolic process (GO:0044042)4.23254289
91cellular glucan metabolic process (GO:0006073)4.23254289
92nucleus organization (GO:0006997)4.19888962
93muscle fiber development (GO:0048747)4.18939655
94chromatin silencing (GO:0006342)4.17966661
95cilium or flagellum-dependent cell motility (GO:0001539)4.16229271
96cell wall macromolecule metabolic process (GO:0044036)4.11846403
97muscle system process (GO:0003012)4.10053581
98cellular response to dexamethasone stimulus (GO:0071549)4.01507617
99fatty acid transmembrane transport (GO:1902001)4.01037574
100regulation of microtubule-based movement (GO:0060632)3.98658623
101negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.94904533
102pyrimidine ribonucleoside catabolic process (GO:0046133)3.92731950
103regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.89448224
104regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)3.85899260
105polyamine biosynthetic process (GO:0006596)3.79763491
106carnitine transmembrane transport (GO:1902603)3.78468682
107negative regulation of skeletal muscle tissue development (GO:0048642)3.76057096
108response to dexamethasone (GO:0071548)3.74795418
109actomyosin structure organization (GO:0031032)3.72943917
110response to activity (GO:0014823)3.71738894
111cytidine metabolic process (GO:0046087)3.66665387
112cytidine catabolic process (GO:0006216)3.66665387
113cytidine deamination (GO:0009972)3.66665387
114regulation of centriole replication (GO:0046599)3.65598026
115cellular response to pH (GO:0071467)3.61493632
116response to acidic pH (GO:0010447)3.60739774
117epithelial cilium movement (GO:0003351)3.59150818
118neuromuscular synaptic transmission (GO:0007274)3.56923911
119regulation of acyl-CoA biosynthetic process (GO:0050812)3.55968754
120cellular carbohydrate catabolic process (GO:0044275)3.51698969
121muscle adaptation (GO:0043500)3.50146364
122organic cation transport (GO:0015695)3.47075497
123musculoskeletal movement (GO:0050881)3.45942814
124multicellular organismal movement (GO:0050879)3.45942814
125cell aggregation (GO:0098743)3.45904289
126cartilage condensation (GO:0001502)3.45904289
127cranial nerve morphogenesis (GO:0021602)3.45769855
128seminiferous tubule development (GO:0072520)3.45707917
129cerebral cortex neuron differentiation (GO:0021895)3.45293341
130microtubule nucleation (GO:0007020)3.44896987
131negative regulation of phosphoprotein phosphatase activity (GO:0032515)3.44228396
132carnitine transport (GO:0015879)3.44084078
133amino-acid betaine transport (GO:0015838)3.44084078
134regulation of female gonad development (GO:2000194)3.41654432
135nucleosome disassembly (GO:0006337)3.38227414
136protein-DNA complex disassembly (GO:0032986)3.38227414
137IMP biosynthetic process (GO:0006188)3.38003617
138keratan sulfate catabolic process (GO:0042340)3.37779097
139histone H3-K9 demethylation (GO:0033169)3.29727921
140negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.29624781
141regulation of skeletal muscle cell differentiation (GO:2001014)3.27894767
142chondrocyte development (GO:0002063)3.27762015
143coenzyme catabolic process (GO:0009109)3.27424161
144muscle organ morphogenesis (GO:0048644)3.26657344
145membrane protein intracellular domain proteolysis (GO:0031293)3.26207153
146glycerol ether metabolic process (GO:0006662)3.24765294
147short-term memory (GO:0007614)3.21954429
148regulation of coenzyme metabolic process (GO:0051196)3.21069348
149regulation of cofactor metabolic process (GO:0051193)3.21069348
150negative regulation of Rho protein signal transduction (GO:0035024)3.16985332
151regulation of calcium ion transmembrane transporter activity (GO:1901019)3.16863400
152regulation of calcium ion transmembrane transport (GO:1903169)3.16863400
153regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)3.15661673
154muscle cell cellular homeostasis (GO:0046716)3.14917236
155negative regulation of muscle hypertrophy (GO:0014741)3.14048628
156regulation of striated muscle contraction (GO:0006942)3.13085075
157negative regulation of cell size (GO:0045792)3.12864461
158cilium movement (GO:0003341)3.12374861
159negative regulation of histone methylation (GO:0031061)3.11584496
160positive regulation of myotube differentiation (GO:0010831)3.10951272
161muscle organ development (GO:0007517)3.09620031
162cellular polysaccharide metabolic process (GO:0044264)3.09598399
163muscle structure development (GO:0061061)3.07560868
164cellular polysaccharide biosynthetic process (GO:0033692)3.07540635
165peptidyl-threonine dephosphorylation (GO:0035970)3.06407912
166polysaccharide biosynthetic process (GO:0000271)3.05137110
167regulation of cardioblast proliferation (GO:0003264)3.03651204
168regulation of secondary heart field cardioblast proliferation (GO:0003266)3.03651204
169homeostasis of number of cells within a tissue (GO:0048873)3.03285588
170multicellular organismal development (GO:0007275)3.02954330
171striated muscle cell development (GO:0055002)3.02478371
172positive regulation of vascular permeability (GO:0043117)3.01440973
173cardiac muscle contraction (GO:0060048)3.01339992
174DNA methylation involved in gamete generation (GO:0043046)3.00918956
175mitochondrial fission (GO:0000266)2.98881869
176otic vesicle formation (GO:0030916)2.97964794
177ether metabolic process (GO:0018904)2.96474452
178positive regulation of skeletal muscle tissue development (GO:0048643)2.95169120
179myotube differentiation (GO:0014902)2.94206367
180vesicle transport along microtubule (GO:0047496)2.92609141
181cellular carbohydrate biosynthetic process (GO:0034637)2.92574318
182piRNA metabolic process (GO:0034587)2.92488289
183polysaccharide metabolic process (GO:0005976)2.91524844
184drinking behavior (GO:0042756)2.89544918
185calcium ion import (GO:0070509)2.89498795
186negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)2.89103520
187regulation of somitogenesis (GO:0014807)2.88578510
188regulation of interleukin-13 production (GO:0032656)2.87810189
189mitochondrial calcium ion homeostasis (GO:0051560)2.87462235
190positive regulation of calcium ion transmembrane transporter activity (GO:1901021)2.87133864
191outer ear morphogenesis (GO:0042473)2.83826380
192tooth mineralization (GO:0034505)2.82826429
193antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.82408589
194acrosome reaction (GO:0007340)11.1234899
195sperm motility (GO:0030317)11.1157022
196actin-myosin filament sliding (GO:0033275)10.2569988
197muscle filament sliding (GO:0030049)10.2569988

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.85905657
2BP1_19119308_ChIP-ChIP_Hs578T_Human4.83579512
3AR_21572438_ChIP-Seq_LNCaP_Human3.85662958
4SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.80920381
5MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human3.47287134
6EZH2_22144423_ChIP-Seq_EOC_Human3.06561271
7PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.60031783
8ESR1_20079471_ChIP-ChIP_T-47D_Human2.28291001
9CDX2_19796622_ChIP-Seq_MESCs_Mouse2.11148035
10POU5F1_26923725_Chip-Seq_MESODERM_Mouse2.09063781
11TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.09063781
12EZH2_27304074_Chip-Seq_ESCs_Mouse2.06874071
13NANOG_20526341_ChIP-Seq_ESCs_Human2.04016173
14ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.99057743
15* ELF1_20517297_ChIP-Seq_JURKAT_Human1.99027572
16RAC3_21632823_ChIP-Seq_H3396_Human1.95219134
17ESR1_21235772_ChIP-Seq_MCF-7_Human1.94137596
18BCL6_27268052_Chip-Seq_Bcells_Human1.89853621
19RNF2_18974828_ChIP-Seq_MESCs_Mouse1.88114416
20EZH2_18974828_ChIP-Seq_MESCs_Mouse1.88114416
21SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.87358603
22ESR2_21235772_ChIP-Seq_MCF-7_Human1.86404551
23CTBP2_25329375_ChIP-Seq_LNCAP_Human1.84264162
24RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.82772155
25TBX20_22080862_ChIP-Seq_HEART_Mouse1.82488345
26TBX20_22328084_ChIP-Seq_HEART_Mouse1.82488345
27* P68_20966046_ChIP-Seq_HELA_Human1.80339816
28EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.79849222
29* ERA_21632823_ChIP-Seq_H3396_Human1.79533979
30TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.78416011
31SMAD_19615063_ChIP-ChIP_OVARY_Human1.78267726
32EZH2_27294783_Chip-Seq_ESCs_Mouse1.76835733
33EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.76248706
34PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.74305330
35* BCOR_27268052_Chip-Seq_Bcells_Human1.73429561
36CTCF_20526341_ChIP-Seq_ESCs_Human1.72140799
37SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.72138673
38VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.70383359
39TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.69660591
40* SMC4_20622854_ChIP-Seq_HELA_Human1.69348022
41PHF8_20622854_ChIP-Seq_HELA_Human1.69299433
42TAF2_19829295_ChIP-Seq_ESCs_Human1.69008459
43EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.68269853
44CTCF_27219007_Chip-Seq_Bcells_Human1.62489999
45* E2F1_20622854_ChIP-Seq_HELA_Human1.62181507
46TP63_22573176_ChIP-Seq_HFKS_Human1.61668886
47SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.60367575
48MTF2_20144788_ChIP-Seq_MESCs_Mouse1.59718066
49JARID2_20075857_ChIP-Seq_MESCs_Mouse1.58717270
50ZNF274_21170338_ChIP-Seq_K562_Hela1.57943336
51SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.57913389
52* LXR_22292898_ChIP-Seq_THP-1_Human1.55283179
53EED_16625203_ChIP-ChIP_MESCs_Mouse1.52269688
54TRIM28_21343339_ChIP-Seq_HEK293_Human1.49647581
55MYC_19829295_ChIP-Seq_ESCs_Human1.49609576
56* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.48936193
57SUZ12_27294783_Chip-Seq_ESCs_Mouse1.48663726
58JARID2_20064375_ChIP-Seq_MESCs_Mouse1.48183736
59FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.46283851
60P63_20808887_ChIP-Seq_KERATINOCYTES_Human1.44569193
61EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.44505126
62RARG_19884340_ChIP-ChIP_MEFs_Mouse1.44123593
63DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.43371086
64AUTS2_25519132_ChIP-Seq_293T-REX_Human1.42943163
65PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.42112292
66P300_27268052_Chip-Seq_Bcells_Human1.41946232
67KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse1.39607525
68UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.39565953
69SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.38155793
70THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.37116691
71* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.35806800
72BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.34867220
73NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.34460980
74RUNX1_26923725_Chip-Seq_HPCs_Mouse1.34292139
75FUS_26573619_Chip-Seq_HEK293_Human1.34189022
76FOXH1_21741376_ChIP-Seq_ESCs_Human1.33154894
77ZNF263_19887448_ChIP-Seq_K562_Human1.32345864
78ERG_20517297_ChIP-Seq_VCAP_Human1.31709070
79STAT6_21828071_ChIP-Seq_BEAS2B_Human1.30806350
80CTCF_21964334_ChIP-Seq_BJAB-B_Human1.29711219
81SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.29253065
82MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.28936404
83ERG_21242973_ChIP-ChIP_JURKAT_Human1.27979631
84* SOX2_22085726_ChIP-Seq_NPCs_Mouse1.27150904
85ETV2_25802403_ChIP-Seq_MESCs_Mouse1.25294941
86CTBP1_25329375_ChIP-Seq_LNCAP_Human1.25005055
87CEBPB_22108803_ChIP-Seq_LS180_Human1.24755875
88P53_21459846_ChIP-Seq_SAOS-2_Human1.24625643
89TP53_20018659_ChIP-ChIP_R1E_Mouse1.24357585
90SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.24139507
91AR_25329375_ChIP-Seq_VCAP_Human1.23783977
92DNAJC2_21179169_ChIP-ChIP_NT2_Human1.23741578
93RARB_27405468_Chip-Seq_BRAIN_Mouse1.23511247
94EP300_21415370_ChIP-Seq_HL-1_Mouse1.23204390
95TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.22929584
96SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.22454464
97TDRD3_21172665_ChIP-Seq_MCF-7_Human1.22058896
98MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.21638419
99SMC1_22415368_ChIP-Seq_MEFs_Mouse1.21189531
100CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.20546898
101SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.20160113
102SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.19665702
103OCT4_19829295_ChIP-Seq_ESCs_Human1.19121964
104HNFA_21074721_ChIP-Seq_CACO-2_Human1.18430729
105P53_22127205_ChIP-Seq_FIBROBLAST_Human1.16717168
106KLF4_19829295_ChIP-Seq_ESCs_Human1.16392779
107GATA3_21878914_ChIP-Seq_MCF-7_Human1.16227774
108ARNT_22903824_ChIP-Seq_MCF-7_Human1.15842158
109SMAD4_21741376_ChIP-Seq_EPCs_Human1.15170044
110RBPJ_21746931_ChIP-Seq_IB4_Human1.14929421
111SMAD3_21741376_ChIP-Seq_ESCs_Human1.14795177
112SA1_27219007_Chip-Seq_ERYTHROID_Human1.14235672
113CBX2_22325352_ChIP-Seq_293T-Rex_Human1.13839844
114* SMC3_22415368_ChIP-Seq_MEFs_Mouse1.13680097
115WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.12401933
116HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.11719027
117CTCF_21964334_Chip-Seq_Bcells_Human1.11441176
118RXR_22108803_ChIP-Seq_LS180_Human1.10985647
119SOX2_21211035_ChIP-Seq_LN229_Gbm1.10891513
120KDM2B_26808549_Chip-Seq_K562_Human1.10316911
121* OCT4_20526341_ChIP-Seq_ESCs_Human1.09850422
122SPI1_20517297_ChIP-Seq_HL60_Human1.09252038
123TP63_19390658_ChIP-ChIP_HaCaT_Human1.08641962
124RNF2_27304074_Chip-Seq_ESCs_Mouse1.07328270
125CJUN_26792858_Chip-Seq_BT549_Human1.07181711
126* DROSHA_22980978_ChIP-Seq_HELA_Human1.05784431
127SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.05660686
128ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.05554127
129PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.05115002
130ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.04929917
131NRF2_20460467_ChIP-Seq_MEFs_Mouse1.04391818
132NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.04391818
133TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.03038814
134NFYB_21822215_ChIP-Seq_K562_Human1.02362483
135TET1_21451524_ChIP-Seq_MESCs_Mouse1.01899159
136CSB_26484114_Chip-Seq_FIBROBLAST_Human1.01755635
137SOX11_22085726_ChIP-Seq_ESNs_Mouse1.01136006
138ETV1_20927104_ChIP-Seq_GIST48_Human1.00922257
139MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.00821702
140CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.00780662
141GATA3_21867929_ChIP-Seq_CD8_Mouse1.00772468
142FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.00487138
143NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.99952503
144GATA1_22025678_ChIP-Seq_K562_Human0.99883175
145HIF1A_21447827_ChIP-Seq_MCF-7_Human0.99481453
146RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.99205194
147CLOCK_20551151_ChIP-Seq_293T_Human0.99096168
148P63_26484246_Chip-Seq_KERATINOCYTES_Human0.98465326
149CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.97349359
150RAD21_21589869_ChIP-Seq_MESCs_Mouse0.96516725
151E2F1_17053090_ChIP-ChIP_MCF-7_Human0.96169584
152TET1_21490601_ChIP-Seq_MESCs_Mouse0.95502849
153CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.95411608
154GATA6_21074721_ChIP-Seq_CACO-2_Human0.95251695
155SMAD4_21741376_ChIP-Seq_ESCs_Human0.94819468
156YY1_22570637_ChIP-Seq_MALME-3M_Human0.94004643
157UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.91017323
158SA1_27219007_Chip-Seq_Bcells_Human0.90113399
159NFIB_24661679_ChIP-Seq_LUNG_Mouse0.89118451
160SMAD3_21741376_ChIP-Seq_EPCs_Human0.88753276
161PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.88723454
162CBP_20019798_ChIP-Seq_JUKART_Human0.88223214
163IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.88223214
164* CREB1_26743006_Chip-Seq_LNCaP_Human0.87553387
165WDR5_24793694_ChIP-Seq_LNCAP_Human0.86752579
166ZFP281_18757296_ChIP-ChIP_E14_Mouse0.85116274
167EGR1_19032775_ChIP-ChIP_M12_Human0.83435346
168RING1B_27294783_Chip-Seq_ESCs_Mouse0.83245115
169EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.82922131
170ER_23166858_ChIP-Seq_MCF-7_Human0.82578540
171TP53_18474530_ChIP-ChIP_U2OS_Human0.81991590
172SMAD4_21741376_ChIP-Seq_HESCs_Human0.81857225
173REST_18959480_ChIP-ChIP_MESCs_Mouse0.81693084
174CBX2_27304074_Chip-Seq_ESCs_Mouse0.80953920

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004145_abnormal_muscle_electrophysio7.54008208
2MP0003646_muscle_fatigue7.14667405
3MP0000751_myopathy5.66077531
4MP0000749_muscle_degeneration5.50886695
5MP0003698_abnormal_male_reproductive3.91178124
6MP0000747_muscle_weakness3.86898322
7MP0002106_abnormal_muscle_physiology3.77920787
8MP0005377_hearing/vestibular/ear_phenot3.69388310
9MP0003878_abnormal_ear_physiology3.69388310
10MP0004036_abnormal_muscle_relaxation3.60928985
11MP0001929_abnormal_gametogenesis3.57106586
12MP0004130_abnormal_muscle_cell3.44037406
13MP0000759_abnormal_skeletal_muscle3.31955503
14MP0002837_dystrophic_cardiac_calcinosis3.23565273
15MP0005369_muscle_phenotype3.19954638
16MP0002269_muscular_atrophy3.05845625
17MP0003718_maternal_effect3.04231641
18MP0004087_abnormal_muscle_fiber2.94165022
19MP0005620_abnormal_muscle_contractility2.68343397
20MP0005451_abnormal_body_composition2.66996298
21MP0004134_abnormal_chest_morphology2.54233540
22MP0001348_abnormal_lacrimal_gland2.49979484
23MP0000678_abnormal_parathyroid_gland2.47090564
24MP0000750_abnormal_muscle_regeneration2.45877544
25MP0002161_abnormal_fertility/fecundity2.36697403
26MP0004233_abnormal_muscle_weight2.29142591
27MP0002108_abnormal_muscle_morphology2.19042289
28MP0002822_catalepsy2.01025793
29MP0005410_abnormal_fertilization10.5630143
30MP0002332_abnormal_exercise_endurance1.98244477
31MP0002249_abnormal_larynx_morphology1.82879464
32MP0009250_abnormal_appendicular_skeleto1.80536679
33MP0004270_analgesia1.76693047
34MP0004185_abnormal_adipocyte_glucose1.70562934
35MP0002210_abnormal_sex_determination1.68570086
36MP0000733_abnormal_muscle_development1.64403999
37MP0003879_abnormal_hair_cell1.64286112
38MP0006036_abnormal_mitochondrial_physio1.64090664
39MP0005330_cardiomyopathy1.54026190
40MP0005423_abnormal_somatic_nervous1.51488102
41MP0003011_delayed_dark_adaptation1.50200905
42MP0004484_altered_response_of1.47204756
43MP0008877_abnormal_DNA_methylation1.47108542
44MP0002127_abnormal_cardiovascular_syste1.43950780
45MP0001299_abnormal_eye_distance/1.37196864
46MP0008789_abnormal_olfactory_epithelium1.36175362
47MP0002933_joint_inflammation1.34848818
48MP0005503_abnormal_tendon_morphology1.34171652
49MP0002132_abnormal_respiratory_system1.31747741
50MP0000653_abnormal_sex_gland1.30830211
51MP0009780_abnormal_chondrocyte_physiolo1.29756757
52MP0001145_abnormal_male_reproductive1.28857315
53MP0004084_abnormal_cardiac_muscle1.24793864
54MP0002282_abnormal_trachea_morphology1.19292003
55MP0005666_abnormal_adipose_tissue1.18123100
56MP0001485_abnormal_pinna_reflex1.17926381
57MP0000762_abnormal_tongue_morphology1.17724532
58MP0005395_other_phenotype1.17309727
59MP0004859_abnormal_synaptic_plasticity1.13351476
60MP0002972_abnormal_cardiac_muscle1.11113205
61MP0005379_endocrine/exocrine_gland_phen1.09997826
62MP0002089_abnormal_postnatal_growth/wei1.08783113
63MP0004510_myositis1.06460090
64MP0000013_abnormal_adipose_tissue1.06149430
65MP0002971_abnormal_brown_adipose1.06062826
66MP0002909_abnormal_adrenal_gland1.05888885
67MP0000049_abnormal_middle_ear1.04410785
68MP0000163_abnormal_cartilage_morphology1.03648609
69MP0000534_abnormal_ureter_morphology1.03079793
70MP0002735_abnormal_chemical_nociception1.02588547
71MP0003806_abnormal_nucleotide_metabolis0.98211593
72MP0005375_adipose_tissue_phenotype0.95895683
73MP0003656_abnormal_erythrocyte_physiolo0.95457310
74MP0004215_abnormal_myocardial_fiber0.95398240
75MP0002896_abnormal_bone_mineralization0.94357316
76MP0005083_abnormal_biliary_tract0.91937397
77MP0005394_taste/olfaction_phenotype0.91398589
78MP0005499_abnormal_olfactory_system0.91398589
79MP0002115_abnormal_skeleton_extremities0.91308079
80MP0000343_altered_response_to0.88094336
81MP0003221_abnormal_cardiomyocyte_apopto0.87814645
82MP0000026_abnormal_inner_ear0.87785658
83MP0005266_abnormal_metabolism0.87778377
84MP0001765_abnormal_ion_homeostasis0.84454266
85MP0005645_abnormal_hypothalamus_physiol0.81032279
86MP0002138_abnormal_hepatobiliary_system0.80286753
87MP0010630_abnormal_cardiac_muscle0.80028003
88MP0003950_abnormal_plasma_membrane0.77667750
89MP0003137_abnormal_impulse_conducting0.77188382
90MP0000681_abnormal_thyroid_gland0.76196309
91MP0001270_distended_abdomen0.75810355
92MP0002229_neurodegeneration0.75023698
93MP0001984_abnormal_olfaction0.73149910
94MP0004085_abnormal_heartbeat0.72576345
95MP0004147_increased_porphyrin_level0.70385383
96MP0009053_abnormal_anal_canal0.69910159
97MP0001544_abnormal_cardiovascular_syste0.69198550
98MP0005385_cardiovascular_system_phenoty0.69198550
99MP0005310_abnormal_salivary_gland0.68884045
100MP0003699_abnormal_female_reproductive0.68851812
101MP0000003_abnormal_adipose_tissue0.68789909
102MP0003122_maternal_imprinting0.68493572
103MP0004142_abnormal_muscle_tone0.67683881
104MP0003123_paternal_imprinting0.66958401
105MP0003705_abnormal_hypodermis_morpholog0.66639471
106MP0005334_abnormal_fat_pad0.65752478
107MP0000955_abnormal_spinal_cord0.64837675
108MP0004742_abnormal_vestibular_system0.64285226
109MP0002078_abnormal_glucose_homeostasis0.63747503
110MP0002067_abnormal_sensory_capabilities0.63282159
111MP0005551_abnormal_eye_electrophysiolog0.62762173
112MP0002734_abnormal_mechanical_nocicepti0.62735316
113MP0002109_abnormal_limb_morphology0.62325302
114MP0003959_abnormal_lean_body0.60242703
115MP0004043_abnormal_pH_regulation0.57236602
116MP0002113_abnormal_skeleton_development0.54012886
117MP0001968_abnormal_touch/_nociception0.52587319
118MP0003077_abnormal_cell_cycle0.52442829
119MP0003755_abnormal_palate_morphology0.50854734
120MP0002114_abnormal_axial_skeleton0.49276464
121MP0001879_abnormal_lymphatic_vessel0.49073711
122MP0005670_abnormal_white_adipose0.48488899
123MP0002557_abnormal_social/conspecific_i0.48224274
124MP0002272_abnormal_nervous_system0.47590869
125MP0008569_lethality_at_weaning0.47279773
126MP0001943_abnormal_respiration0.46597638
127MP0006035_abnormal_mitochondrial_morpho0.45717921
128MP0005636_abnormal_mineral_homeostasis0.45613416
129MP0003195_calcinosis0.43094663
130MP0001905_abnormal_dopamine_level0.43044134
131MP0002066_abnormal_motor_capabilities/c0.42959909
132MP0005452_abnormal_adipose_tissue0.42941035
133MP0008961_abnormal_basal_metabolism0.42578708
134MP0005508_abnormal_skeleton_morphology0.42190499
135MP0008995_early_reproductive_senescence0.42119010
136MP0002733_abnormal_thermal_nociception0.41830885
137MP0000230_abnormal_systemic_arterial0.41787515
138MP0006138_congestive_heart_failure0.41604584
139MP0003635_abnormal_synaptic_transmissio0.39438858
140MP0005275_abnormal_skin_tensile0.39329237
141MP0000920_abnormal_myelination0.38609978
142MP0005584_abnormal_enzyme/coenzyme_acti0.37957001
143MP0008775_abnormal_heart_ventricle0.37655317
144MP0000266_abnormal_heart_morphology0.37232522
145MP0009384_cardiac_valve_regurgitation0.36089091
146MP0005535_abnormal_body_temperature0.35835203
147MP0001963_abnormal_hearing_physiology0.35550779
148MP0002234_abnormal_pharynx_morphology0.35262996
149MP0003948_abnormal_gas_homeostasis0.35242961
150MP0003045_fibrosis0.35064731
151MP0005166_decreased_susceptibility_to0.34789744
152MP0001440_abnormal_grooming_behavior0.33960977
153MP0003787_abnormal_imprinting0.33321649
154MP0009115_abnormal_fat_cell0.32253742
155MP0001486_abnormal_startle_reflex0.31976411
156MP0008004_abnormal_stomach_pH0.31888377

Predicted human phenotypes

RankGene SetZ-score
1Muscle fiber inclusion bodies (HP:0100299)8.35928598
2Exercise-induced myalgia (HP:0003738)7.80835665
3Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)7.80562666
4Nemaline bodies (HP:0003798)7.13484897
5Exercise-induced muscle cramps (HP:0003710)7.01264858
6Ulnar deviation of the wrist (HP:0003049)6.57917840
7Severe visual impairment (HP:0001141)6.36381581
8Distal arthrogryposis (HP:0005684)6.22956015
9Type 1 muscle fiber predominance (HP:0003803)5.87571790
10Muscle hypertrophy of the lower extremities (HP:0008968)5.87282337
11Muscle fiber splitting (HP:0003555)5.38008372
12Round ear (HP:0100830)5.25016664
13Myopathic facies (HP:0002058)5.21893717
14Calf muscle hypertrophy (HP:0008981)4.95879931
15Dynein arm defect of respiratory motile cilia (HP:0012255)4.89695248
16Absent/shortened dynein arms (HP:0200106)4.89695248
17Calcaneovalgus deformity (HP:0001848)4.80585452
18Myoglobinuria (HP:0002913)4.67102490
19Absent phalangeal crease (HP:0006109)4.59771313
20Tubulointerstitial nephritis (HP:0001970)4.59764356
21Hypoplastic ischia (HP:0003175)4.58306142
22Difficulty running (HP:0009046)4.45664582
23Epiphyseal dysplasia (HP:0002656)4.36342241
24Muscle stiffness (HP:0003552)4.29890837
25Deformed tarsal bones (HP:0008119)4.29779021
26Male infertility (HP:0003251)4.26013517
27Aplasia/Hypoplasia of the pubic bone (HP:0009104)4.13316690
28Abnormality of the ischium (HP:0003174)4.00731492
29Hyporeflexia of lower limbs (HP:0002600)3.95035203
30Infertility (HP:0000789)3.91152159
31Irregular epiphyses (HP:0010582)3.88023146
32EMG: myopathic abnormalities (HP:0003458)3.87912363
33Chronic hepatic failure (HP:0100626)3.84419022
34Myotonia (HP:0002486)3.81191564
35Abnormal finger flexion creases (HP:0006143)3.80805256
36Attenuation of retinal blood vessels (HP:0007843)3.77248051
37Rhabdomyolysis (HP:0003201)3.75319566
38Bony spicule pigmentary retinopathy (HP:0007737)3.70717113
39Abnormal ciliary motility (HP:0012262)3.67521567
40Abnormality of the calf musculature (HP:0001430)3.60652401
41Increased connective tissue (HP:0009025)3.59603481
42Abnormal respiratory motile cilium physiology (HP:0012261)3.57759232
43Resting tremor (HP:0002322)3.56513245
44Abnormality of the calcaneus (HP:0008364)3.43379787
45Parkinsonism with favorable response to dopaminergic medication (HP:0002548)3.41290233
46Cone-rod dystrophy (HP:0000548)3.39378980
47Abnormal respiratory motile cilium morphology (HP:0005938)3.37661275
48Abnormal respiratory epithelium morphology (HP:0012253)3.37661275
49Hypoalphalipoproteinemia (HP:0003233)3.35770670
50Bell-shaped thorax (HP:0001591)3.25303502
51Impulsivity (HP:0100710)3.22388195
52Nasal polyposis (HP:0100582)3.19241835
53Abnormality of macular pigmentation (HP:0008002)3.10790957
54Waddling gait (HP:0002515)3.05962737
55Shoulder girdle muscle weakness (HP:0003547)3.02914102
56Malignant hyperthermia (HP:0002047)3.02358853
57Abnormality of skeletal muscle fiber size (HP:0012084)2.98926578
58Unilateral renal agenesis (HP:0000122)2.98344858
59Rimmed vacuoles (HP:0003805)2.98263111
60Abnormal spermatogenesis (HP:0008669)2.95820295
61Pelvic girdle muscle weakness (HP:0003749)2.95045051
62Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.94185214
63Ventricular tachycardia (HP:0004756)2.92721966
64Facial shape deformation (HP:0011334)2.90871037
65Potter facies (HP:0002009)2.90871037
66Double outlet right ventricle (HP:0001719)2.88616260
67Congenital malformation of the right heart (HP:0011723)2.88616260
68Insulin-resistant diabetes mellitus (HP:0000831)2.84691260
69Neck muscle weakness (HP:0000467)2.83563535
70Azoospermia (HP:0000027)2.83077512
71Abnormality of the musculature of the pelvis (HP:0001469)2.82598992
72Abnormality of the hip-girdle musculature (HP:0001445)2.82598992
73Aplasia/Hypoplasia of the earlobes (HP:0009906)2.82564343
74Increased variability in muscle fiber diameter (HP:0003557)2.81126291
75Small epiphyses (HP:0010585)2.78891182
76Cupped ribs (HP:0000887)2.78792967
77Abnormality of the left ventricular outflow tract (HP:0011103)2.70562016
78Subaortic stenosis (HP:0001682)2.70562016
79Difficulty climbing stairs (HP:0003551)2.69894529
80Progressive sensorineural hearing impairment (HP:0000408)2.66232833
81Truncal obesity (HP:0001956)2.65720452
82Distal lower limb muscle weakness (HP:0009053)2.65376376
83Abnormal rod and cone electroretinograms (HP:0008323)2.65015543
84Hyperkalemia (HP:0002153)2.61438784
85Abnormality of potassium homeostasis (HP:0011042)2.59964823
86Abnormality of the nasal mucosa (HP:0000433)2.59908242
87Postural instability (HP:0002172)2.59540298
88Vitreoretinal degeneration (HP:0000655)2.57450974
89Hip contracture (HP:0003273)2.55381736
90Flat acetabular roof (HP:0003180)2.54070229
91Abnormality of the aortic arch (HP:0012303)2.53469032
92Generalized aminoaciduria (HP:0002909)2.52229831
93Hyperuricemia (HP:0002149)2.50178095
94Increased purine levels (HP:0004368)2.50178095
95Abnormal tarsal ossification (HP:0008369)2.49726136
96Areflexia of lower limbs (HP:0002522)2.46362650
97Limited hip movement (HP:0008800)2.42275638
98Renal dysplasia (HP:0000110)2.34276735
99Hypoplasia of the thymus (HP:0000778)2.33166401
100Metaphyseal cupping (HP:0003021)2.32057985
101Abnormality of the pubic bones (HP:0003172)2.31390785
102Abnormality of the parathyroid morphology (HP:0011766)2.30852306
103Nonprogressive disorder (HP:0003680)2.30821278
104Renovascular hypertension (HP:0100817)2.26900954
105Delayed epiphyseal ossification (HP:0002663)2.26262616
106Genu varum (HP:0002970)2.25874684
107Stridor (HP:0010307)2.24987199
108Proximal amyotrophy (HP:0007126)2.24594995
109Asymmetric septal hypertrophy (HP:0001670)2.23001520
110Amelogenesis imperfecta (HP:0000705)2.21086490
111Limb-girdle muscle atrophy (HP:0003797)2.20429763
112Abnormality of the vertebral endplates (HP:0005106)2.19880545
113Anterior segment dysgenesis (HP:0007700)2.19707645
114Flat capital femoral epiphysis (HP:0003370)2.17262024
115Limb-girdle muscle weakness (HP:0003325)2.17195330
116Centrally nucleated skeletal muscle fibers (HP:0003687)2.16423786
117Frequent falls (HP:0002359)2.14265762
118Periauricular skin pits (HP:0100277)2.14030878
119Preauricular pit (HP:0004467)2.14030878
120Paralysis (HP:0003470)2.12444047
121Abnormal urine output (HP:0012590)2.11947662
122Muscular dystrophy (HP:0003560)2.08695066
123Enlarged epiphyses (HP:0010580)2.08464041
124Mild short stature (HP:0003502)2.07662573
125Abnormality involving the epiphyses of the lower limbs (HP:0006500)2.04022079
126Abnormality of femoral epiphyses (HP:0006499)2.04022079
127Muscle fiber atrophy (HP:0100295)2.03974002
128Rhinitis (HP:0012384)2.02704283
129Distal lower limb amyotrophy (HP:0008944)2.00232490
130Ovoid vertebral bodies (HP:0003300)1.99648895
131Hypophosphatemic rickets (HP:0004912)1.99209127
132Skin pits (HP:0100276)1.98959566
133Fetal akinesia sequence (HP:0001989)1.98340009
134Bowel incontinence (HP:0002607)1.97559197
135Hypoplastic heart (HP:0001961)1.97415020
136Stage 5 chronic kidney disease (HP:0003774)1.96928664
137Tubulointerstitial abnormality (HP:0001969)1.96472563
138Abnormality of dental color (HP:0011073)1.96379511
139Metatarsus adductus (HP:0001840)1.96263736
140Osteomalacia (HP:0002749)1.95798316
141Slender build (HP:0001533)1.95063381
142Scapular winging (HP:0003691)1.94764876
143Mesomelia (HP:0003027)1.92796471
144Abnormality of the shoulder girdle musculature (HP:0001435)1.92729653
145Abnormality of the epiphysis of the femoral head (HP:0010574)1.92409461
146Hypoplastic left heart (HP:0004383)1.92224431
147Hyponatremia (HP:0002902)1.91662496
148Menstrual irregularities (HP:0000858)1.91462939
149Long clavicles (HP:0000890)1.89543539
150Ulnar deviation of finger (HP:0009465)1.87051932
151Sudden death (HP:0001699)1.86902173
152Irregular vertebral endplates (HP:0003301)1.86851520
153Neonatal short-limb short stature (HP:0008921)1.86723443
154EMG: neuropathic changes (HP:0003445)1.85533543
155Abnormality of the costochondral junction (HP:0000919)1.85011236
156Subcapsular cataract (HP:0000523)1.84144812
157Abnormal large intestine physiology (HP:0012700)1.80415158
158Spinal rigidity (HP:0003306)1.79467434
159Abnormality of the neuromuscular junction (HP:0003398)1.74968528
160Fatigable weakness (HP:0003473)1.74968528
161Ulnar deviation of the hand or of fingers of the hand (HP:0001193)1.73807498
162Abnormality of the femoral head (HP:0003368)1.73034472
163Mildly elevated creatine phosphokinase (HP:0008180)1.72184469
164Short femoral neck (HP:0100864)1.71191720
165Achilles tendon contracture (HP:0001771)1.71020493
166Metaphyseal dysplasia (HP:0100255)1.69518369
167Carpal bone hypoplasia (HP:0001498)1.68787829
168Gowers sign (HP:0003391)1.68030166
169Osteoarthritis (HP:0002758)1.65916262

Predicted kinase interactions (KEA)

RankGene SetZ-score
1OBSCN7.71123827
2PLK47.21584287
3NME16.22880389
4TESK15.82606954
5PHKG15.61139698
6PHKG25.61139698
7TTN5.19697524
8STK383.30663888
9BRD42.97505191
10MAP3K32.60419301
11PRKD32.56188440
12PIK3CG2.40473990
13MAP2K32.24164940
14MAP4K22.19114162
15DYRK1B1.92964489
16MAPK121.92459975
17MAPK151.90789237
18PIK3CA1.71904915
19NEK11.70615949
20PDK21.69490138
21STK241.67822645
22PINK11.67384606
23MAP3K71.62864638
24EPHB11.62566183
25DDR21.58038567
26MAP2K41.52969321
27ARAF1.52593208
28MST1R1.51215986
29CDK121.46547189
30MAP2K61.45189122
31PDK31.40316979
32PDK41.40316979
33BRAF1.39174117
34TRIB31.37152347
35WNK11.35019897
36BCKDK1.32733874
37CDK71.22172490
38TAOK11.20821822
39STK38L1.19421440
40DMPK1.05138413
41MUSK1.04190992
42TNIK0.98628453
43PTK2B0.95103110
44ERBB30.91591987
45PRKAA10.86817278
46PRKAA20.86554841
47AKT30.80019131
48MAP3K130.78912832
49PKN10.75837911
50TYRO30.72509197
51SIK10.70037772
52MET0.69986173
53CAMK1D0.68538079
54NEK90.64584287
55CAMK2G0.63746044
56LIMK10.62967670
57SIK20.62800889
58MAP3K80.62608210
59EEF2K0.62521313
60KSR20.61080924
61MTOR0.58621125
62TRPM70.58458254
63LATS10.56048916
64RPS6KA10.55010167
65MARK10.54790507
66MAPK40.53196653
67RPS6KA20.52437095
68NTRK30.50935532
69PNCK0.50872605
70GSK3B0.50167662
71CDK20.48525688
72MAPKAPK30.48140875
73PAK60.47322887
74TESK20.47207588
75CDK10.47207376
76KSR10.45143112
77CAMK40.44694942
78WNK40.44646850
79SGK10.44372503
80NEK60.44080132
81MAPK70.41576366
82MAP3K110.40421758
83TIE10.39265074
84MAP2K20.38841591
85PRKG10.38263634
86ICK0.38076986
87ROCK10.37591236
88MAPK110.37179380
89CHEK10.36923788
90MAPK80.35852682
91MAP3K20.35377922
92MAPK10.35034913
93AURKA0.33881989
94CDK90.31894500
95AKT20.31083908
96SGK2230.30503163
97SGK4940.30503163
98PDPK10.30115193
99CDK190.29641460
100STK110.29013294
101LMTK20.28150115
102PRKG20.28104434
103DYRK1A0.26739222
104PDK10.26684025
105MAPK140.26368808
106PTK60.26021798
107RPS6KA30.25841987
108GSK3A0.25391051
109PRKACB0.25338607
110OXSR10.24882512
111PRKCZ0.24790063
112PRKACA0.23715982
113TAOK20.23657967
114LATS20.23070716
115INSRR0.22471757
116MAP2K10.22284819
117BRSK10.21855154
118MAP3K10.21526455
119STK390.21006085
120CAMKK20.20672136
121PLK20.20057978
122ROCK20.19863809
123RPS6KC10.18946541
124RPS6KL10.18946541
125GRK70.18889210
126CAMK2A0.18613944
127PAK10.17949588
128PRKACG0.17726671
129CSNK1D0.17615487
130CDK30.17457786
131ILK0.17288780
132STK30.17023701
133TAF10.17023450
134CDK50.16264542
135MAP3K90.15659565
136CAMK2D0.14912866
137CAMK2B0.14704787
138PAK30.14577241
139CSNK1G20.14468411
140CAMK1G0.14462085
141UHMK10.11786333
142MAPK100.11579276
143MOS0.11293935
144CSNK1G30.10589382
145MAP3K60.09764447
146CSNK1A1L0.09367370
147MAP3K40.06086979
148MAPK130.05212389
149MARK20.04643409
150PRKD10.04158259
151MAP3K50.04153755
152PRKCA0.03736034
153BCR0.03463848
154CAMK10.03376157

Predicted pathways (KEGG)

RankGene SetZ-score
1Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054103.61294210
2Starch and sucrose metabolism_Homo sapiens_hsa005003.24698904
3Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054123.24267785
4Citrate cycle (TCA cycle)_Homo sapiens_hsa000203.18087246
5Cardiac muscle contraction_Homo sapiens_hsa042603.00180977
6Dilated cardiomyopathy_Homo sapiens_hsa054142.99158549
72-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.62835633
8Oxytocin signaling pathway_Homo sapiens_hsa049212.39814996
9Glucagon signaling pathway_Homo sapiens_hsa049222.29732859
10Circadian rhythm_Homo sapiens_hsa047102.25536501
11Insulin signaling pathway_Homo sapiens_hsa049102.01114096
12Propanoate metabolism_Homo sapiens_hsa006401.93885314
13Arginine and proline metabolism_Homo sapiens_hsa003301.90950626
14Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.88433293
15Glycerophospholipid metabolism_Homo sapiens_hsa005641.82697189
16Phenylalanine metabolism_Homo sapiens_hsa003601.80030890
17Calcium signaling pathway_Homo sapiens_hsa040201.79405452
18Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.77175270
19Galactose metabolism_Homo sapiens_hsa000521.77004959
20Insulin resistance_Homo sapiens_hsa049311.76157858
21Sulfur metabolism_Homo sapiens_hsa009201.73916072
22Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.63300813
23Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.60455971
24Carbon metabolism_Homo sapiens_hsa012001.57930493
25RNA transport_Homo sapiens_hsa030131.52881386
26Adipocytokine signaling pathway_Homo sapiens_hsa049201.52525960
27AMPK signaling pathway_Homo sapiens_hsa041521.50992596
28Parkinsons disease_Homo sapiens_hsa050121.45323323
29Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.42158187
30Dorso-ventral axis formation_Homo sapiens_hsa043201.39144706
31ECM-receptor interaction_Homo sapiens_hsa045121.38686800
32Fructose and mannose metabolism_Homo sapiens_hsa000511.37623962
33Alzheimers disease_Homo sapiens_hsa050101.34348834
34Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.34060070
35Taste transduction_Homo sapiens_hsa047421.32441663
36Gastric acid secretion_Homo sapiens_hsa049711.31363063
37cGMP-PKG signaling pathway_Homo sapiens_hsa040221.30778381
38Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.30403718
39Oxidative phosphorylation_Homo sapiens_hsa001901.29631263
40Focal adhesion_Homo sapiens_hsa045101.25711854
41Phototransduction_Homo sapiens_hsa047441.23920713
42Oocyte meiosis_Homo sapiens_hsa041141.22702352
43Vascular smooth muscle contraction_Homo sapiens_hsa042701.21940211
44Pyruvate metabolism_Homo sapiens_hsa006201.17354067
45Biosynthesis of amino acids_Homo sapiens_hsa012301.09499727
46Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.07940937
47Insulin secretion_Homo sapiens_hsa049111.05487807
48Protein digestion and absorption_Homo sapiens_hsa049741.05013541
49Inositol phosphate metabolism_Homo sapiens_hsa005621.03538220
50Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.03043125
51Tight junction_Homo sapiens_hsa045301.00941628
52Olfactory transduction_Homo sapiens_hsa047400.97454643
53GnRH signaling pathway_Homo sapiens_hsa049120.96231372
54Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.92478824
55Long-term depression_Homo sapiens_hsa047300.92210659
56Synaptic vesicle cycle_Homo sapiens_hsa047210.91747372
57Thyroid hormone signaling pathway_Homo sapiens_hsa049190.90700059
58Caffeine metabolism_Homo sapiens_hsa002320.90403629
59Viral myocarditis_Homo sapiens_hsa054160.89289231
60Renin secretion_Homo sapiens_hsa049240.87977575
61Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.86586444
62Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.86439287
63Circadian entrainment_Homo sapiens_hsa047130.85095250
64Longevity regulating pathway - mammal_Homo sapiens_hsa042110.82762102
65Basal transcription factors_Homo sapiens_hsa030220.82014819
66Fatty acid degradation_Homo sapiens_hsa000710.81218724
67Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.80816015
68Endocytosis_Homo sapiens_hsa041440.79171371
69Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.76786720
70Arginine biosynthesis_Homo sapiens_hsa002200.74985823
71Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.73955207
72GABAergic synapse_Homo sapiens_hsa047270.73745697
73Aldosterone synthesis and secretion_Homo sapiens_hsa049250.73416082
74FoxO signaling pathway_Homo sapiens_hsa040680.71317445
75Phosphatidylinositol signaling system_Homo sapiens_hsa040700.71221358
76Fatty acid metabolism_Homo sapiens_hsa012120.71193398
77Fatty acid biosynthesis_Homo sapiens_hsa000610.68600924
78Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.67952635
79Tyrosine metabolism_Homo sapiens_hsa003500.66891985
80HIF-1 signaling pathway_Homo sapiens_hsa040660.66122935
81Purine metabolism_Homo sapiens_hsa002300.65816036
82Morphine addiction_Homo sapiens_hsa050320.64320099
83Hedgehog signaling pathway_Homo sapiens_hsa043400.62932654
84MAPK signaling pathway_Homo sapiens_hsa040100.61895242
85Butanoate metabolism_Homo sapiens_hsa006500.61801408
86Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.60345127
87Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.59722900
88Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.59303107
89Type II diabetes mellitus_Homo sapiens_hsa049300.58298332
90Nicotine addiction_Homo sapiens_hsa050330.56144426
91Central carbon metabolism in cancer_Homo sapiens_hsa052300.55812021
92Cholinergic synapse_Homo sapiens_hsa047250.55090810
93Huntingtons disease_Homo sapiens_hsa050160.53812188
94Long-term potentiation_Homo sapiens_hsa047200.52693346
95ABC transporters_Homo sapiens_hsa020100.50970381
96Fat digestion and absorption_Homo sapiens_hsa049750.50704335
97Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.49205346
98Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.49148444
99mTOR signaling pathway_Homo sapiens_hsa041500.48774305
100Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.48313765
101Amphetamine addiction_Homo sapiens_hsa050310.48237937
102Salivary secretion_Homo sapiens_hsa049700.47654680
103Gap junction_Homo sapiens_hsa045400.47276421
104Pentose phosphate pathway_Homo sapiens_hsa000300.46589612
105Platelet activation_Homo sapiens_hsa046110.45058109
106Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.43919916
107Pentose and glucuronate interconversions_Homo sapiens_hsa000400.43413693
108Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.40185874
109Regulation of actin cytoskeleton_Homo sapiens_hsa048100.39771408
110Bile secretion_Homo sapiens_hsa049760.39231675
111Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.39212842
112Glycerolipid metabolism_Homo sapiens_hsa005610.39210248
113Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.38698198
114Dopaminergic synapse_Homo sapiens_hsa047280.38240295
115Melanogenesis_Homo sapiens_hsa049160.37532785
116Ovarian steroidogenesis_Homo sapiens_hsa049130.37252459
117Estrogen signaling pathway_Homo sapiens_hsa049150.36171650
118Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.35144413
119cAMP signaling pathway_Homo sapiens_hsa040240.34007133
120Renin-angiotensin system_Homo sapiens_hsa046140.33333946
121Renal cell carcinoma_Homo sapiens_hsa052110.32622567
122Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.31646793
123PPAR signaling pathway_Homo sapiens_hsa033200.31580724
124Maturity onset diabetes of the young_Homo sapiens_hsa049500.31551930
125VEGF signaling pathway_Homo sapiens_hsa043700.31499823
126Glutamatergic synapse_Homo sapiens_hsa047240.30691717
127Metabolic pathways_Homo sapiens_hsa011000.30403995
128Vibrio cholerae infection_Homo sapiens_hsa051100.29772897
129Nitrogen metabolism_Homo sapiens_hsa009100.29172690
130mRNA surveillance pathway_Homo sapiens_hsa030150.29139407
131Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.28937538
132Leukocyte transendothelial migration_Homo sapiens_hsa046700.28791766
133Sulfur relay system_Homo sapiens_hsa041220.28598528
134Phagosome_Homo sapiens_hsa041450.28142016
135Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.28085233
136Pancreatic secretion_Homo sapiens_hsa049720.27979400
137TGF-beta signaling pathway_Homo sapiens_hsa043500.27586516
138Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.26895686
139Amoebiasis_Homo sapiens_hsa051460.26839087
140Proteoglycans in cancer_Homo sapiens_hsa052050.26694770
141Peroxisome_Homo sapiens_hsa041460.21511013
142Antigen processing and presentation_Homo sapiens_hsa046120.20801209

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