Rank | Gene Set | Z-score |
---|---|---|
1 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 6.21977998 |
2 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 6.21977998 |
3 | antigen processing and presentation of endogenous antigen (GO:0019883) | 5.43941653 |
4 | response to peptidoglycan (GO:0032494) | 4.41421103 |
5 | negative regulation of cell killing (GO:0031342) | 4.23697176 |
6 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.23697176 |
7 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.10997338 |
8 | macrophage activation involved in immune response (GO:0002281) | 4.08398454 |
9 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 3.84869873 |
10 | detection of other organism (GO:0098543) | 3.76510113 |
11 | detection of bacterium (GO:0016045) | 3.71670176 |
12 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.68482493 |
13 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 3.62306070 |
14 | neutrophil activation involved in immune response (GO:0002283) | 3.59653753 |
15 | germinal center formation (GO:0002467) | 3.51188982 |
16 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.50356197 |
17 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 3.49194058 |
18 | pentose-phosphate shunt (GO:0006098) | 3.38118109 |
19 | regulation of gamma-delta T cell activation (GO:0046643) | 3.37803805 |
20 | positive regulation of interferon-alpha production (GO:0032727) | 3.31114013 |
21 | detection of external biotic stimulus (GO:0098581) | 3.27840561 |
22 | maternal placenta development (GO:0001893) | 3.26101403 |
23 | positive regulation of Cdc42 GTPase activity (GO:0043089) | 3.24384269 |
24 | response to type I interferon (GO:0034340) | 3.17748310 |
25 | DNA unwinding involved in DNA replication (GO:0006268) | 3.17542276 |
26 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.16954727 |
27 | leukocyte aggregation (GO:0070486) | 3.16619546 |
28 | low-density lipoprotein particle clearance (GO:0034383) | 3.14416762 |
29 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.14206058 |
30 | type I interferon signaling pathway (GO:0060337) | 3.12006176 |
31 | cellular response to type I interferon (GO:0071357) | 3.12006176 |
32 | regulation of interferon-alpha production (GO:0032647) | 3.11119300 |
33 | detection of molecule of bacterial origin (GO:0032490) | 3.09358142 |
34 | mannose metabolic process (GO:0006013) | 3.05579839 |
35 | NADPH regeneration (GO:0006740) | 3.05130256 |
36 | regulation of cholesterol storage (GO:0010885) | 3.03727846 |
37 | positive regulation of histone deacetylation (GO:0031065) | 3.03439824 |
38 | T cell apoptotic process (GO:0070231) | 3.01704787 |
39 | defense response to protozoan (GO:0042832) | 2.95305723 |
40 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.95183991 |
41 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 2.92540468 |
42 | NIK/NF-kappaB signaling (GO:0038061) | 2.92342436 |
43 | morphogenesis of an endothelium (GO:0003159) | 2.91216961 |
44 | endothelial tube morphogenesis (GO:0061154) | 2.91216961 |
45 | regulation of leukocyte degranulation (GO:0043300) | 2.90382284 |
46 | modulation by symbiont of host cellular process (GO:0044068) | 2.89947749 |
47 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 2.89748999 |
48 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 2.89748999 |
49 | modulation by symbiont of host immune response (GO:0052553) | 2.89748999 |
50 | positive regulation by symbiont of host defense response (GO:0052509) | 2.89748999 |
51 | modulation by symbiont of host defense response (GO:0052031) | 2.89748999 |
52 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 2.89748999 |
53 | response to protozoan (GO:0001562) | 2.88934692 |
54 | JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397) | 2.88134174 |
55 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 2.87127968 |
56 | detection of biotic stimulus (GO:0009595) | 2.86688146 |
57 | regulation of mast cell degranulation (GO:0043304) | 2.85835287 |
58 | viral transcription (GO:0019083) | 2.83786742 |
59 | epithelial cell differentiation involved in prostate gland development (GO:0060742) | 2.82851310 |
60 | protein localization to endosome (GO:0036010) | 2.82274007 |
61 | folic acid-containing compound biosynthetic process (GO:0009396) | 2.81646618 |
62 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 2.81379450 |
63 | positive regulation of natural killer cell differentiation (GO:0032825) | 2.81249945 |
64 | response to interferon-alpha (GO:0035455) | 2.81051571 |
65 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 2.80886588 |
66 | regulation of interferon-beta biosynthetic process (GO:0045357) | 2.77274901 |
67 | natural killer cell differentiation (GO:0001779) | 2.76379027 |
68 | response to host immune response (GO:0052572) | 2.73588085 |
69 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 2.73588085 |
70 | positive regulation of type 2 immune response (GO:0002830) | 2.73540449 |
71 | T-helper 1 type immune response (GO:0042088) | 2.73392561 |
72 | myeloid dendritic cell activation (GO:0001773) | 2.71731173 |
73 | apoptotic cell clearance (GO:0043277) | 2.71219600 |
74 | positive regulation of membrane protein ectodomain proteolysis (GO:0051044) | 2.70323666 |
75 | immunoglobulin mediated immune response (GO:0016064) | 2.67539507 |
76 | translational termination (GO:0006415) | 2.66958265 |
77 | macrophage activation (GO:0042116) | 2.66913809 |
78 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 2.66660783 |
79 | response to host (GO:0075136) | 2.66660783 |
80 | response to host defenses (GO:0052200) | 2.66660783 |
81 | regulation of T-helper 1 cell differentiation (GO:0045625) | 2.64598676 |
82 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.64260208 |
83 | regulation of type 2 immune response (GO:0002828) | 2.63454326 |
84 | cellular response to virus (GO:0098586) | 2.63256266 |
85 | regulation of response to interferon-gamma (GO:0060330) | 2.63232756 |
86 | granulocyte activation (GO:0036230) | 2.61825281 |
87 | response to laminar fluid shear stress (GO:0034616) | 2.61095820 |
88 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 2.61064742 |
89 | negative regulation of leukocyte mediated immunity (GO:0002704) | 2.59639277 |
90 | regulation of T cell tolerance induction (GO:0002664) | 2.59537042 |
91 | positive thymic T cell selection (GO:0045059) | 2.59374488 |
92 | myeloid cell activation involved in immune response (GO:0002275) | 2.59149186 |
93 | regulation of translational fidelity (GO:0006450) | 2.57546187 |
94 | regulation of protein heterodimerization activity (GO:0043497) | 2.55847805 |
95 | positive regulation of cellular amide metabolic process (GO:0034250) | 2.55511681 |
96 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 2.54838589 |
97 | barbed-end actin filament capping (GO:0051016) | 2.54255857 |
98 | ribosomal small subunit assembly (GO:0000028) | 2.52969099 |
99 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 2.52939633 |
100 | cellular extravasation (GO:0045123) | 2.52390115 |
101 | negative regulation of type 2 immune response (GO:0002829) | 2.52155845 |
102 | translational elongation (GO:0006414) | 2.51679504 |
103 | activation of MAPKKK activity (GO:0000185) | 2.49963235 |
104 | regulation of mast cell activation involved in immune response (GO:0033006) | 2.49806852 |
105 | negative regulation of toll-like receptor signaling pathway (GO:0034122) | 2.49511365 |
106 | regulation of antigen processing and presentation (GO:0002577) | 2.49141229 |
107 | modulation by virus of host process (GO:0019054) | 2.48940161 |
108 | lymphocyte apoptotic process (GO:0070227) | 2.48715412 |
109 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.48704632 |
110 | regulation of necroptotic process (GO:0060544) | 2.48473420 |
111 | negative regulation of toll-like receptor 4 signaling pathway (GO:0034144) | 2.48197032 |
112 | positive regulation of B cell differentiation (GO:0045579) | 2.47058342 |
113 | neutrophil activation (GO:0042119) | 2.46667712 |
114 | negative regulation of innate immune response (GO:0045824) | 2.46455095 |
115 | COPI coating of Golgi vesicle (GO:0048205) | 2.46376997 |
116 | Golgi transport vesicle coating (GO:0048200) | 2.46376997 |
117 | cellular response to interferon-alpha (GO:0035457) | 2.45731487 |
118 | negative regulation of cell size (GO:0045792) | 2.44773418 |
119 | negative regulation of myeloid cell apoptotic process (GO:0033033) | 2.44412357 |
120 | respiratory burst (GO:0045730) | 2.43392356 |
121 | regulation of interferon-gamma-mediated signaling pathway (GO:0060334) | 2.43159996 |
122 | sexual reproduction (GO:0019953) | 2.42940123 |
123 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 2.41934088 |
124 | negative regulation of viral release from host cell (GO:1902187) | 2.40884251 |
125 | positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557) | 2.40743685 |
126 | regulation of vitamin D biosynthetic process (GO:0060556) | 2.40626774 |
127 | regulation of cholesterol homeostasis (GO:2000188) | 2.40412139 |
128 | regulation of fatty acid beta-oxidation (GO:0031998) | 2.40355443 |
129 | positive regulation of protein deacetylation (GO:0090312) | 2.39554576 |
130 | negative regulation of T cell mediated immunity (GO:0002710) | 2.39382879 |
131 | interferon-gamma secretion (GO:0072643) | 2.38682923 |
132 | regulation of superoxide anion generation (GO:0032928) | 2.38668413 |
133 | positive regulation of antigen processing and presentation (GO:0002579) | 2.38507027 |
134 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 2.36763452 |
135 | B cell mediated immunity (GO:0019724) | 2.36329290 |
136 | heterochromatin organization (GO:0070828) | 2.36113976 |
137 | 4-hydroxyproline metabolic process (GO:0019471) | 2.33573888 |
138 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 2.33222873 |
139 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.30395657 |
140 | response to muramyl dipeptide (GO:0032495) | 2.26408562 |
141 | positive regulation of triglyceride biosynthetic process (GO:0010867) | 2.24778520 |
142 | positive regulation of nuclease activity (GO:0032075) | 2.23871450 |
143 | apoptotic process involved in morphogenesis (GO:0060561) | 2.22545485 |
144 | negative regulation of interleukin-12 production (GO:0032695) | 2.22348995 |
145 | leukocyte apoptotic process (GO:0071887) | 2.21496430 |
146 | basement membrane organization (GO:0071711) | 2.21296110 |
147 | myeloid cell homeostasis (GO:0002262) | 2.20777952 |
148 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 2.19998909 |
149 | positive regulation of interferon-beta production (GO:0032728) | 2.19806127 |
150 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.19768261 |
151 | positive regulation of lipid storage (GO:0010884) | 2.18262860 |
152 | negative regulation of fibrinolysis (GO:0051918) | 2.17882381 |
153 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO | 2.17791946 |
154 | peptidyl-lysine dimethylation (GO:0018027) | 2.17728043 |
155 | negative regulation of cytokine production involved in immune response (GO:0002719) | 2.16755631 |
156 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.16162671 |
157 | myeloid dendritic cell differentiation (GO:0043011) | 2.14545847 |
158 | platelet aggregation (GO:0070527) | 2.13355043 |
159 | viral life cycle (GO:0019058) | 2.12494445 |
160 | RNA stabilization (GO:0043489) | 2.12381419 |
161 | mRNA stabilization (GO:0048255) | 2.12381419 |
162 | regulation of nuclease activity (GO:0032069) | 2.11779257 |
163 | cell adhesion mediated by integrin (GO:0033627) | 2.10841509 |
164 | pinocytosis (GO:0006907) | 2.10562605 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 3.34365623 |
2 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 3.11531621 |
3 | MYC_22102868_ChIP-Seq_BL_Human | 3.11393043 |
4 | E2F7_22180533_ChIP-Seq_HELA_Human | 3.06691550 |
5 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.96543428 |
6 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.92095659 |
7 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.68255499 |
8 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 2.52827674 |
9 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 2.29499761 |
10 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.28131178 |
11 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 2.20091663 |
12 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.19506437 |
13 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.10047459 |
14 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.10004167 |
15 | MAF_26560356_Chip-Seq_TH1_Human | 1.99465380 |
16 | * IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.99325212 |
17 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.91115181 |
18 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.89578397 |
19 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.86928916 |
20 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.85055216 |
21 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.82804792 |
22 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.80376071 |
23 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.79041576 |
24 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.78565794 |
25 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.78284839 |
26 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.78248204 |
27 | UTX_26944678_Chip-Seq_JUKART_Human | 1.77846603 |
28 | * LXR_22292898_ChIP-Seq_THP-1_Human | 1.77830959 |
29 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.75797117 |
30 | * KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.73883138 |
31 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.64676620 |
32 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.64513126 |
33 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.63228522 |
34 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.62386086 |
35 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.61178084 |
36 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.58903317 |
37 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.58694002 |
38 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.57687479 |
39 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.57458766 |
40 | KDM2B_26808549_Chip-Seq_K562_Human | 1.54592382 |
41 | * ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.54041524 |
42 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.52561629 |
43 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.49951716 |
44 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.49233960 |
45 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.48605838 |
46 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.46554610 |
47 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.41982763 |
48 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.41303492 |
49 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.41128349 |
50 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.40627051 |
51 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.40572507 |
52 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.40520026 |
53 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.38508306 |
54 | MAF_26560356_Chip-Seq_TH2_Human | 1.38329672 |
55 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.38269793 |
56 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.36855047 |
57 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.36686414 |
58 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.36438931 |
59 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.35921454 |
60 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.35538988 |
61 | * SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.34105026 |
62 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.33980451 |
63 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.32839547 |
64 | MYB_26560356_Chip-Seq_TH2_Human | 1.32384842 |
65 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.31817950 |
66 | ATF3_27146783_Chip-Seq_COLON_Human | 1.31107683 |
67 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.30647755 |
68 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.30228096 |
69 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.28133972 |
70 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.26610392 |
71 | MYB_26560356_Chip-Seq_TH1_Human | 1.25607411 |
72 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.25538451 |
73 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.24362268 |
74 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.24179620 |
75 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.21943215 |
76 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.21450136 |
77 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.21224241 |
78 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.20643196 |
79 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.20460069 |
80 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.20028078 |
81 | * SPI1_23547873_ChIP-Seq_NB4_Human | 1.19707619 |
82 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.17881378 |
83 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.17072176 |
84 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.17065598 |
85 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.16699129 |
86 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.15885252 |
87 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.15470449 |
88 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.14982431 |
89 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.14307842 |
90 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.13993699 |
91 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.13760369 |
92 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.12862464 |
93 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.12640101 |
94 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.11689322 |
95 | * SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.11035894 |
96 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.10538265 |
97 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.10298472 |
98 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.09334564 |
99 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.07407111 |
100 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.07134677 |
101 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.07114796 |
102 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.05504435 |
103 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.05500928 |
104 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 1.05448573 |
105 | GATA1_19941826_ChIP-Seq_K562_Human | 1.05424779 |
106 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.03868752 |
107 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.03707554 |
108 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.03209450 |
109 | * SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.02968199 |
110 | SPI1_23127762_ChIP-Seq_K562_Human | 1.02564427 |
111 | * FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.02277899 |
112 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.01786011 |
113 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.01093363 |
114 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.99982842 |
115 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.99810644 |
116 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 0.99196256 |
117 | * ZFP281_18757296_ChIP-ChIP_E14_Mouse | 0.98673013 |
118 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 0.98357101 |
119 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.98123538 |
120 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.97325122 |
121 | * ZFX_18555785_ChIP-Seq_MESCs_Mouse | 0.97273696 |
122 | P68_20966046_ChIP-Seq_HELA_Human | 0.96341460 |
123 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.96324014 |
124 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.96292923 |
125 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.96168342 |
126 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.96166492 |
127 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 0.94928462 |
128 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.94442890 |
129 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.94433747 |
130 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.93445528 |
131 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.91282604 |
132 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 0.91102191 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003705_abnormal_hypodermis_morpholog | 3.86770000 |
2 | MP0005451_abnormal_body_composition | 2.92770292 |
3 | MP0003303_peritoneal_inflammation | 2.84156889 |
4 | MP0009840_abnormal_foam_cell | 2.80325712 |
5 | MP0000685_abnormal_immune_system | 2.45332593 |
6 | MP0010352_gastrointestinal_tract_polyps | 2.38405613 |
7 | MP0008438_abnormal_cutaneous_collagen | 2.37821400 |
8 | MP0003436_decreased_susceptibility_to | 2.36640575 |
9 | MP0003300_gastrointestinal_ulcer | 2.32991588 |
10 | MP0001835_abnormal_antigen_presentation | 2.23336916 |
11 | MP0009278_abnormal_bone_marrow | 2.16053124 |
12 | MP0003191_abnormal_cellular_cholesterol | 2.09819057 |
13 | MP0008260_abnormal_autophagy | 2.04177113 |
14 | MP0005076_abnormal_cell_differentiation | 1.98567990 |
15 | MP0009785_altered_susceptibility_to | 1.80493175 |
16 | MP0004510_myositis | 1.75272945 |
17 | MP0001790_abnormal_immune_system | 1.69001927 |
18 | MP0005387_immune_system_phenotype | 1.69001927 |
19 | MP0001800_abnormal_humoral_immune | 1.68295063 |
20 | MP0003075_altered_response_to | 1.67318853 |
21 | MP0003566_abnormal_cell_adhesion | 1.67011060 |
22 | MP0005360_urolithiasis | 1.66870296 |
23 | MP0004947_skin_inflammation | 1.65395914 |
24 | MP0005023_abnormal_wound_healing | 1.60932185 |
25 | MP0005025_abnormal_response_to | 1.59220385 |
26 | MP0002452_abnormal_antigen_presenting | 1.59085678 |
27 | MP0004808_abnormal_hematopoietic_stem | 1.56817313 |
28 | MP0005058_abnormal_lysosome_morphology | 1.52822475 |
29 | MP0005000_abnormal_immune_tolerance | 1.52597333 |
30 | MP0010307_abnormal_tumor_latency | 1.46918963 |
31 | MP0005464_abnormal_platelet_physiology | 1.44650150 |
32 | MP0001545_abnormal_hematopoietic_system | 1.43825182 |
33 | MP0005397_hematopoietic_system_phenotyp | 1.43825182 |
34 | MP0002723_abnormal_immune_serum | 1.43546792 |
35 | MP0009333_abnormal_splenocyte_physiolog | 1.43264087 |
36 | MP0002419_abnormal_innate_immunity | 1.39582315 |
37 | MP0002398_abnormal_bone_marrow | 1.38856732 |
38 | MP0001819_abnormal_immune_cell | 1.38589696 |
39 | MP0002166_altered_tumor_susceptibility | 1.38494715 |
40 | MP0006054_spinal_hemorrhage | 1.37376607 |
41 | MP0002420_abnormal_adaptive_immunity | 1.37364781 |
42 | MP0001533_abnormal_skeleton_physiology | 1.36316368 |
43 | MP0006082_CNS_inflammation | 1.34745550 |
44 | MP0005310_abnormal_salivary_gland | 1.33149810 |
45 | MP0001849_ear_inflammation | 1.32911824 |
46 | MP0003183_abnormal_peptide_metabolism | 1.31130624 |
47 | MP0005083_abnormal_biliary_tract | 1.31023166 |
48 | MP0009764_decreased_sensitivity_to | 1.28783715 |
49 | MP0010155_abnormal_intestine_physiology | 1.26434584 |
50 | MP0000858_altered_metastatic_potential | 1.26138692 |
51 | MP0002139_abnormal_hepatobiliary_system | 1.25978930 |
52 | MP0002405_respiratory_system_inflammati | 1.25625567 |
53 | MP0000733_abnormal_muscle_development | 1.25274793 |
54 | MP0002722_abnormal_immune_system | 1.23702865 |
55 | MP0000716_abnormal_immune_system | 1.23089155 |
56 | MP0003091_abnormal_cell_migration | 1.22217446 |
57 | MP0005671_abnormal_response_to | 1.21995738 |
58 | MP0004858_abnormal_nervous_system | 1.21509210 |
59 | MP0000689_abnormal_spleen_morphology | 1.18213516 |
60 | MP0002396_abnormal_hematopoietic_system | 1.16734149 |
61 | MP0003448_altered_tumor_morphology | 1.16701279 |
62 | MP0010234_abnormal_vibrissa_follicle | 1.16640174 |
63 | MP0002429_abnormal_blood_cell | 1.16495092 |
64 | MP0003763_abnormal_thymus_physiology | 1.15459270 |
65 | MP0001853_heart_inflammation | 1.14449473 |
66 | MP0005166_decreased_susceptibility_to | 1.14141072 |
67 | MP0003329_amyloid_beta_deposits | 1.14024894 |
68 | MP0003690_abnormal_glial_cell | 1.14023555 |
69 | MP0003279_aneurysm | 1.13682466 |
70 | MP0001845_abnormal_inflammatory_respons | 1.12831191 |
71 | MP0008469_abnormal_protein_level | 1.08500342 |
72 | MP0000609_abnormal_liver_physiology | 1.06819078 |
73 | MP0000703_abnormal_thymus_morphology | 1.04546553 |
74 | MP0000598_abnormal_liver_morphology | 1.03526860 |
75 | MP0001958_emphysema | 1.03034509 |
76 | MP0003172_abnormal_lysosome_physiology | 1.02566456 |
77 | MP0000604_amyloidosis | 1.02232353 |
78 | MP0003866_abnormal_defecation | 1.01567959 |
79 | MP0001915_intracranial_hemorrhage | 1.01309860 |
80 | MP0002148_abnormal_hypersensitivity_rea | 1.00831296 |
81 | MP0002254_reproductive_system_inflammat | 0.99999317 |
82 | MP0003828_pulmonary_edema | 0.99874344 |
83 | MP0001851_eye_inflammation | 0.97061508 |
84 | MP0001730_embryonic_growth_arrest | 0.96508052 |
85 | MP0005666_abnormal_adipose_tissue | 0.94734741 |
86 | MP0000343_altered_response_to | 0.94281372 |
87 | MP0002006_tumorigenesis | 0.94221867 |
88 | MP0004381_abnormal_hair_follicle | 0.92624472 |
89 | MP0000465_gastrointestinal_hemorrhage | 0.92579424 |
90 | MP0003221_abnormal_cardiomyocyte_apopto | 0.92519134 |
91 | MP0002933_joint_inflammation | 0.92269207 |
92 | MP0004197_abnormal_fetal_growth/weight/ | 0.90021899 |
93 | MP0004185_abnormal_adipocyte_glucose | 0.89576067 |
94 | MP0001663_abnormal_digestive_system | 0.87414523 |
95 | MP0000767_abnormal_smooth_muscle | 0.86719401 |
96 | MP0005164_abnormal_response_to | 0.86697757 |
97 | MP0003453_abnormal_keratinocyte_physiol | 0.86494993 |
98 | MP0001348_abnormal_lacrimal_gland | 0.85012586 |
99 | MP0000490_abnormal_crypts_of | 0.84725682 |
100 | MP0003077_abnormal_cell_cycle | 0.84343279 |
101 | MP0004883_abnormal_blood_vessel | 0.83747739 |
102 | MP0010368_abnormal_lymphatic_system | 0.83485331 |
103 | MP0008874_decreased_physiological_sensi | 0.82926897 |
104 | MP0002877_abnormal_melanocyte_morpholog | 0.82824735 |
105 | MP0010329_abnormal_lipoprotein_level | 0.82536829 |
106 | MP0002019_abnormal_tumor_incidence | 0.80494479 |
107 | MP0005275_abnormal_skin_tensile | 0.80361460 |
108 | MP0005319_abnormal_enzyme/_coenzyme | 0.78336108 |
109 | MP0008961_abnormal_basal_metabolism | 0.77332600 |
110 | MP0005390_skeleton_phenotype | 0.76919705 |
111 | MP0003724_increased_susceptibility_to | 0.76844848 |
112 | MP0002998_abnormal_bone_remodeling | 0.76542189 |
113 | MP0008004_abnormal_stomach_pH | 0.76374489 |
114 | MP0002332_abnormal_exercise_endurance | 0.76357749 |
115 | MP0002089_abnormal_postnatal_growth/wei | 0.76294890 |
116 | MP0002138_abnormal_hepatobiliary_system | 0.75918218 |
117 | MP0000350_abnormal_cell_proliferation | 0.75076550 |
118 | MP0002132_abnormal_respiratory_system | 0.74896205 |
119 | MP0010630_abnormal_cardiac_muscle | 0.74123486 |
120 | MP0002088_abnormal_embryonic_growth/wei | 0.73746817 |
121 | MP0002086_abnormal_extraembryonic_tissu | 0.73683193 |
122 | MP0009763_increased_sensitivity_to | 0.73347771 |
123 | MP0001873_stomach_inflammation | 0.73254120 |
124 | MP0005375_adipose_tissue_phenotype | 0.72877188 |
125 | MP0003795_abnormal_bone_structure | 0.72661720 |
126 | MP0000249_abnormal_blood_vessel | 0.71665514 |
127 | MP0003806_abnormal_nucleotide_metabolis | 0.71078835 |
128 | MP0003656_abnormal_erythrocyte_physiolo | 0.69728681 |
129 | MP0000678_abnormal_parathyroid_gland | 0.69593305 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormality of glycolipid metabolism (HP:0010969) | 3.70383977 |
2 | Abnormality of liposaccharide metabolism (HP:0010968) | 3.70383977 |
3 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 3.70383977 |
4 | Orchitis (HP:0100796) | 3.62649658 |
5 | Chronic otitis media (HP:0000389) | 3.62298681 |
6 | Protrusio acetabuli (HP:0003179) | 3.60951315 |
7 | Cerebral aneurysm (HP:0004944) | 3.33334612 |
8 | Optic neuritis (HP:0100653) | 3.21336387 |
9 | Retrobulbar optic neuritis (HP:0100654) | 3.21336387 |
10 | Dysostosis multiplex (HP:0000943) | 3.21333509 |
11 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.19905626 |
12 | Abnormality of the nasal mucosa (HP:0000433) | 3.01457009 |
13 | Peritonitis (HP:0002586) | 2.99214183 |
14 | Loss of speech (HP:0002371) | 2.98388670 |
15 | Nasal polyposis (HP:0100582) | 2.97276903 |
16 | Obstructive lung disease (HP:0006536) | 2.80003933 |
17 | Chronic obstructive pulmonary disease (HP:0006510) | 2.80003933 |
18 | Eczematoid dermatitis (HP:0000976) | 2.78530663 |
19 | Gingivitis (HP:0000230) | 2.78366014 |
20 | Increased IgE level (HP:0003212) | 2.76651115 |
21 | Hyperacusis (HP:0010780) | 2.71292782 |
22 | Increased density of long bones (HP:0006392) | 2.67819312 |
23 | Deep venous thrombosis (HP:0002625) | 2.65142844 |
24 | Gastrointestinal infarctions (HP:0005244) | 2.61109334 |
25 | Meningitis (HP:0001287) | 2.59068990 |
26 | Shallow orbits (HP:0000586) | 2.59060951 |
27 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.55705021 |
28 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.55705021 |
29 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.55705021 |
30 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.52552935 |
31 | Stomatitis (HP:0010280) | 2.51640868 |
32 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.51136815 |
33 | Mucopolysacchariduria (HP:0008155) | 2.51136815 |
34 | Recurrent skin infections (HP:0001581) | 2.50941451 |
35 | Interstitial pulmonary disease (HP:0006530) | 2.50836969 |
36 | Amyloidosis (HP:0011034) | 2.46335599 |
37 | Purpura (HP:0000979) | 2.45668562 |
38 | Vasculitis (HP:0002633) | 2.41001911 |
39 | Axonal loss (HP:0003447) | 2.37526789 |
40 | Cellulitis (HP:0100658) | 2.35486608 |
41 | Hematochezia (HP:0002573) | 2.35181619 |
42 | Vertebral compression fractures (HP:0002953) | 2.34683549 |
43 | Spastic diplegia (HP:0001264) | 2.32392185 |
44 | Aortic aneurysm (HP:0004942) | 2.31561168 |
45 | Hemorrhage of the eye (HP:0011885) | 2.31399389 |
46 | Premature rupture of membranes (HP:0001788) | 2.31149291 |
47 | Upper limb amyotrophy (HP:0009129) | 2.29721162 |
48 | Distal upper limb amyotrophy (HP:0007149) | 2.29721162 |
49 | Autoimmune thrombocytopenia (HP:0001973) | 2.29541733 |
50 | Hand muscle atrophy (HP:0009130) | 2.29088334 |
51 | Thrombocytosis (HP:0001894) | 2.28272611 |
52 | Malnutrition (HP:0004395) | 2.27878530 |
53 | Recurrent bronchitis (HP:0002837) | 2.24275750 |
54 | Dilatation of the ascending aorta (HP:0005111) | 2.23373324 |
55 | Keratoconjunctivitis sicca (HP:0001097) | 2.21968633 |
56 | Ulnar bowing (HP:0003031) | 2.21870119 |
57 | Recurrent viral infections (HP:0004429) | 2.21265426 |
58 | Vacuolated lymphocytes (HP:0001922) | 2.18646337 |
59 | Gastrointestinal stroma tumor (HP:0100723) | 2.18529936 |
60 | Cervical subluxation (HP:0003308) | 2.17617754 |
61 | Neurofibrillary tangles (HP:0002185) | 2.17436199 |
62 | Myocardial infarction (HP:0001658) | 2.17129334 |
63 | Nuclear cataract (HP:0100018) | 2.17066995 |
64 | Aneurysm (HP:0002617) | 2.15416653 |
65 | Pulmonary infiltrates (HP:0002113) | 2.15070546 |
66 | Neuronal loss in central nervous system (HP:0002529) | 2.14522503 |
67 | Glomerulonephritis (HP:0000099) | 2.14367855 |
68 | Mitral valve prolapse (HP:0001634) | 2.14289138 |
69 | Spontaneous hematomas (HP:0007420) | 2.14157496 |
70 | Polycythemia (HP:0001901) | 2.12677596 |
71 | Recurrent abscess formation (HP:0002722) | 2.11376313 |
72 | Polygenic inheritance (HP:0010982) | 2.11068929 |
73 | Urticaria (HP:0001025) | 2.10640774 |
74 | Multiple enchondromatosis (HP:0005701) | 2.10229659 |
75 | Broad face (HP:0000283) | 2.09405485 |
76 | Abnormality of the peritoneum (HP:0002585) | 2.06925321 |
77 | J-shaped sella turcica (HP:0002680) | 2.06658221 |
78 | Recurrent bacterial skin infections (HP:0005406) | 2.05252695 |
79 | Ankle contracture (HP:0006466) | 2.04903349 |
80 | Colitis (HP:0002583) | 2.04748241 |
81 | Emphysema (HP:0002097) | 2.03960438 |
82 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.03560249 |
83 | Subacute progressive viral hepatitis (HP:0006572) | 2.00581056 |
84 | Gastrointestinal inflammation (HP:0004386) | 2.00449072 |
85 | Cerebral inclusion bodies (HP:0100314) | 1.99966995 |
86 | Segmental peripheral demyelination/remyelination (HP:0003481) | 1.98627097 |
87 | Genu recurvatum (HP:0002816) | 1.97000824 |
88 | Ectopia lentis (HP:0001083) | 1.95406673 |
89 | Keratoconjunctivitis (HP:0001096) | 1.94205742 |
90 | Radial bowing (HP:0002986) | 1.93604564 |
91 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 1.93524963 |
92 | Short 4th metacarpal (HP:0010044) | 1.93524963 |
93 | Hemoptysis (HP:0002105) | 1.93499610 |
94 | Obstructive sleep apnea (HP:0002870) | 1.93083496 |
95 | Thin bony cortex (HP:0002753) | 1.92966993 |
96 | Hepatosplenomegaly (HP:0001433) | 1.91696732 |
97 | Systemic lupus erythematosus (HP:0002725) | 1.90984568 |
98 | Arterial thrombosis (HP:0004420) | 1.90246896 |
99 | Encephalitis (HP:0002383) | 1.89865560 |
100 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 1.89573485 |
101 | Xanthomatosis (HP:0000991) | 1.89242827 |
102 | Pathologic fracture (HP:0002756) | 1.88871343 |
103 | Bladder diverticulum (HP:0000015) | 1.88612286 |
104 | Recurrent cutaneous fungal infections (HP:0011370) | 1.88571146 |
105 | Chronic mucocutaneous candidiasis (HP:0002728) | 1.88571146 |
106 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 1.87944097 |
107 | Petechiae (HP:0000967) | 1.87786304 |
108 | Broad metatarsal (HP:0001783) | 1.87329947 |
109 | Abnormality of the Achilles tendon (HP:0005109) | 1.85049956 |
110 | Pustule (HP:0200039) | 1.84638101 |
111 | Verrucae (HP:0200043) | 1.84295612 |
112 | Papilloma (HP:0012740) | 1.84295612 |
113 | Epistaxis (HP:0000421) | 1.84039315 |
114 | Persistence of primary teeth (HP:0006335) | 1.83831622 |
115 | Disinhibition (HP:0000734) | 1.83609519 |
116 | Prolonged bleeding time (HP:0003010) | 1.82973490 |
117 | Bone pain (HP:0002653) | 1.82826936 |
118 | Increased serum ferritin (HP:0003281) | 1.82749678 |
119 | Slow saccadic eye movements (HP:0000514) | 1.82626989 |
120 | Bicuspid aortic valve (HP:0001647) | 1.82619011 |
121 | Recurrent fungal infections (HP:0002841) | 1.82223112 |
122 | Esophageal varix (HP:0002040) | 1.81483019 |
123 | Myositis (HP:0100614) | 1.81455234 |
124 | Achilles tendon contracture (HP:0001771) | 1.81412080 |
125 | Thoracic kyphosis (HP:0002942) | 1.81130024 |
126 | Aortic dissection (HP:0002647) | 1.80574412 |
127 | Complement deficiency (HP:0004431) | 1.80424747 |
128 | Bowing of the arm (HP:0006488) | 1.80303235 |
129 | Bowed forearm bones (HP:0003956) | 1.80303235 |
130 | Hypertriglyceridemia (HP:0002155) | 1.80055669 |
131 | Supranuclear gaze palsy (HP:0000605) | 1.79513671 |
132 | Abnormal cartilage morphology (HP:0002763) | 1.77221020 |
133 | Lymphangioma (HP:0100764) | 1.77036991 |
134 | Restrictive lung disease (HP:0002091) | 1.76985403 |
135 | Abnormality of the thoracic spine (HP:0100711) | 1.76372282 |
136 | Chest pain (HP:0100749) | 1.76121339 |
137 | Inflammation of the large intestine (HP:0002037) | 1.75680946 |
138 | Pulmonary embolism (HP:0002204) | 1.75420641 |
139 | Osteomyelitis (HP:0002754) | 1.75254462 |
140 | Blue sclerae (HP:0000592) | 1.75027749 |
141 | Disproportionate tall stature (HP:0001519) | 1.74595512 |
142 | Increased connective tissue (HP:0009025) | 1.74533053 |
143 | Long toe (HP:0010511) | 1.74530753 |
144 | Abnormality of the 4th metacarpal (HP:0010012) | 1.73561183 |
145 | Hallux valgus (HP:0001822) | 1.73414693 |
146 | Abnormality of macrophages (HP:0004311) | 1.73037615 |
147 | Increased cerebral lipofuscin (HP:0011813) | 1.72625908 |
148 | Abnormal platelet volume (HP:0011876) | 1.71091813 |
149 | Abnormality of iron homeostasis (HP:0011031) | 1.70026177 |
150 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.69825624 |
151 | Osteolytic defects of the hand bones (HP:0009699) | 1.69825624 |
152 | Mediastinal lymphadenopathy (HP:0100721) | 1.69411680 |
153 | Deviation of the hallux (HP:0010051) | 1.69408732 |
154 | Abnormality of complement system (HP:0005339) | 1.68716499 |
155 | Striae distensae (HP:0001065) | 1.68288231 |
156 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 1.67789577 |
157 | Spinal cord lesions (HP:0100561) | 1.67228173 |
158 | Syringomyelia (HP:0003396) | 1.67228173 |
159 | Mesangial abnormality (HP:0001966) | 1.66753153 |
160 | Increased mean platelet volume (HP:0011877) | 1.66533985 |
161 | Mitral stenosis (HP:0001718) | 1.65498077 |
162 | Cortical dysplasia (HP:0002539) | 1.65138792 |
163 | Tetraparesis (HP:0002273) | 1.64909168 |
164 | Biconcave vertebral bodies (HP:0004586) | 1.64442430 |
165 | Camptodactyly of toe (HP:0001836) | 1.63589113 |
166 | Bowel diverticulosis (HP:0005222) | 1.63373099 |
167 | Renal duplication (HP:0000075) | 1.63342938 |
168 | Viral hepatitis (HP:0006562) | 1.59555386 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRIB3 | 4.41134946 |
2 | PKN2 | 4.02815726 |
3 | MAP3K10 | 3.90807948 |
4 | ERN1 | 3.25870524 |
5 | PRPF4B | 3.17402600 |
6 | EEF2K | 3.09935624 |
7 | IRAK3 | 2.93565129 |
8 | RIPK4 | 2.74211865 |
9 | MAP4K1 | 2.66174814 |
10 | FGFR4 | 2.60169869 |
11 | TBK1 | 2.27754795 |
12 | TYK2 | 2.20054847 |
13 | SMG1 | 2.15708340 |
14 | IRAK4 | 2.15260356 |
15 | TTN | 2.02134548 |
16 | LRRK2 | 1.91375231 |
17 | PTK6 | 1.87560694 |
18 | BLK | 1.83463655 |
19 | TAOK2 | 1.73695967 |
20 | JAK3 | 1.73541997 |
21 | MAP3K13 | 1.58590186 |
22 | STK10 | 1.52703812 |
23 | RPS6KA4 | 1.52474498 |
24 | SCYL2 | 1.52342642 |
25 | SIK1 | 1.49854527 |
26 | ZAP70 | 1.41630806 |
27 | MAP2K3 | 1.40297088 |
28 | PDGFRA | 1.37140443 |
29 | FLT3 | 1.36518030 |
30 | TNK2 | 1.32675593 |
31 | RIPK1 | 1.32053562 |
32 | TESK2 | 1.31130448 |
33 | NME2 | 1.30883035 |
34 | KIT | 1.30243740 |
35 | MAP3K1 | 1.29473062 |
36 | PAK4 | 1.27218874 |
37 | CDC42BPA | 1.26834396 |
38 | IKBKE | 1.26648752 |
39 | TGFBR1 | 1.24033912 |
40 | NEK2 | 1.23222640 |
41 | GRK6 | 1.22130871 |
42 | EPHB1 | 1.20196070 |
43 | JAK1 | 1.18977512 |
44 | FGFR3 | 1.17409898 |
45 | SIK3 | 1.14095702 |
46 | FGR | 1.12599195 |
47 | KDR | 1.11960948 |
48 | BMX | 1.11419791 |
49 | TGFBR2 | 1.09375648 |
50 | IRAK2 | 1.09162841 |
51 | MARK2 | 1.07974012 |
52 | MAP3K11 | 1.07210605 |
53 | BCKDK | 1.04146233 |
54 | MAP3K8 | 1.02386153 |
55 | PASK | 1.02133400 |
56 | PRKD2 | 1.01422438 |
57 | TESK1 | 1.00956702 |
58 | FES | 1.00383333 |
59 | BTK | 0.96535598 |
60 | PDPK1 | 0.95647963 |
61 | CSF1R | 0.93189797 |
62 | EPHA2 | 0.86338174 |
63 | CDK4 | 0.85911697 |
64 | CDC7 | 0.83309869 |
65 | ALK | 0.82660780 |
66 | ILK | 0.81849032 |
67 | HCK | 0.81007663 |
68 | DYRK1B | 0.80622976 |
69 | TAOK1 | 0.79146451 |
70 | ITK | 0.79014900 |
71 | DDR2 | 0.78135445 |
72 | JAK2 | 0.76964859 |
73 | CSK | 0.76871586 |
74 | PDK1 | 0.76641149 |
75 | RPS6KB2 | 0.75680016 |
76 | MAP3K14 | 0.74621414 |
77 | CDK12 | 0.74535973 |
78 | ICK | 0.74172812 |
79 | MAP3K6 | 0.73655340 |
80 | CDK6 | 0.72926260 |
81 | PAK2 | 0.72573399 |
82 | IKBKB | 0.72422031 |
83 | MOS | 0.71519945 |
84 | SIK2 | 0.69947150 |
85 | MTOR | 0.69907550 |
86 | RPS6KC1 | 0.69222472 |
87 | RPS6KL1 | 0.69222472 |
88 | ARAF | 0.68528744 |
89 | CHUK | 0.66835432 |
90 | RPS6KA2 | 0.65870882 |
91 | MAP3K3 | 0.63721861 |
92 | SYK | 0.63457460 |
93 | PIM1 | 0.63301165 |
94 | PTK2 | 0.63259427 |
95 | GRK7 | 0.62476413 |
96 | STK4 | 0.62212433 |
97 | MARK3 | 0.61088628 |
98 | FGFR1 | 0.60682895 |
99 | IRAK1 | 0.57169179 |
100 | PIM2 | 0.56458284 |
101 | CAMKK1 | 0.56100171 |
102 | EPHA3 | 0.55500005 |
103 | MAPK11 | 0.54094505 |
104 | LCK | 0.53961608 |
105 | MAP2K2 | 0.53944346 |
106 | RET | 0.53219721 |
107 | MAPK12 | 0.52690207 |
108 | MAP2K6 | 0.51898748 |
109 | RPS6KA6 | 0.50918739 |
110 | PDGFRB | 0.48261046 |
111 | EPHB2 | 0.48227701 |
112 | NEK9 | 0.47529606 |
113 | KSR2 | 0.45464938 |
114 | PRKG2 | 0.45250438 |
115 | MAPK7 | 0.44754214 |
116 | NEK1 | 0.44198604 |
117 | MAP3K7 | 0.42932380 |
118 | DAPK3 | 0.41237645 |
119 | EGFR | 0.41218497 |
120 | TYRO3 | 0.39564968 |
121 | MAPKAPK3 | 0.39264493 |
122 | BUB1 | 0.37326242 |
123 | LYN | 0.34103179 |
124 | DYRK3 | 0.33102040 |
125 | RPS6KA1 | 0.32798573 |
126 | MAPKAPK2 | 0.29650589 |
127 | PAK1 | 0.29025019 |
128 | HIPK2 | 0.27968945 |
129 | MST1R | 0.27076343 |
130 | STK3 | 0.27042817 |
131 | MAP3K5 | 0.25414649 |
132 | CLK1 | 0.24814108 |
133 | MATK | 0.24573206 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Other glycan degradation_Homo sapiens_hsa00511 | 2.91509006 |
2 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 2.18587695 |
3 | Leishmaniasis_Homo sapiens_hsa05140 | 2.07822652 |
4 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.86378368 |
5 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.86065834 |
6 | Allograft rejection_Homo sapiens_hsa05330 | 1.82037652 |
7 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.76958077 |
8 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.65032189 |
9 | Measles_Homo sapiens_hsa05162 | 1.64103757 |
10 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.64060601 |
11 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.58419103 |
12 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.57339410 |
13 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.54719125 |
14 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.52120202 |
15 | Legionellosis_Homo sapiens_hsa05134 | 1.51477753 |
16 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.51097429 |
17 | Sulfur relay system_Homo sapiens_hsa04122 | 1.49769082 |
18 | Viral myocarditis_Homo sapiens_hsa05416 | 1.47439526 |
19 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.47411417 |
20 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.45180523 |
21 | Apoptosis_Homo sapiens_hsa04210 | 1.43961474 |
22 | Shigellosis_Homo sapiens_hsa05131 | 1.40967429 |
23 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.39029450 |
24 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.38725906 |
25 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.37989194 |
26 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.37226249 |
27 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.36789207 |
28 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.34013450 |
29 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.32066776 |
30 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.28718233 |
31 | Influenza A_Homo sapiens_hsa05164 | 1.25778182 |
32 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.23454081 |
33 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.22542419 |
34 | Hepatitis B_Homo sapiens_hsa05161 | 1.20890953 |
35 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.20819375 |
36 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.19969452 |
37 | Asthma_Homo sapiens_hsa05310 | 1.15970148 |
38 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.14984616 |
39 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 1.14841518 |
40 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.13431046 |
41 | Pertussis_Homo sapiens_hsa05133 | 1.12813807 |
42 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.11847311 |
43 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.11758744 |
44 | DNA replication_Homo sapiens_hsa03030 | 1.11142177 |
45 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.10632213 |
46 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.09130744 |
47 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.06907007 |
48 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.06456803 |
49 | Bladder cancer_Homo sapiens_hsa05219 | 1.05986880 |
50 | Malaria_Homo sapiens_hsa05144 | 1.04875535 |
51 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.04598347 |
52 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.02145725 |
53 | HTLV-I infection_Homo sapiens_hsa05166 | 1.01611807 |
54 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 1.01423366 |
55 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.01348674 |
56 | Ribosome_Homo sapiens_hsa03010 | 1.01161017 |
57 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.01055956 |
58 | Phagosome_Homo sapiens_hsa04145 | 0.99963707 |
59 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.99928398 |
60 | Insulin resistance_Homo sapiens_hsa04931 | 0.97346993 |
61 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.95347737 |
62 | Tuberculosis_Homo sapiens_hsa05152 | 0.95102115 |
63 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.93969408 |
64 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.92974840 |
65 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.92904720 |
66 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.91289933 |
67 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.90093798 |
68 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.90029514 |
69 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.90019645 |
70 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.87671359 |
71 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.87038097 |
72 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.85091134 |
73 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.83874452 |
74 | Lysine degradation_Homo sapiens_hsa00310 | 0.83779826 |
75 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.82798500 |
76 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.81451795 |
77 | Amoebiasis_Homo sapiens_hsa05146 | 0.81430517 |
78 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.81161212 |
79 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.80567552 |
80 | Focal adhesion_Homo sapiens_hsa04510 | 0.80432257 |
81 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.79643937 |
82 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.79179917 |
83 | Hepatitis C_Homo sapiens_hsa05160 | 0.78790655 |
84 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.78500823 |
85 | Salmonella infection_Homo sapiens_hsa05132 | 0.78313831 |
86 | Spliceosome_Homo sapiens_hsa03040 | 0.77784027 |
87 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.76179956 |
88 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.75715710 |
89 | Lysosome_Homo sapiens_hsa04142 | 0.75541416 |
90 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.75496992 |
91 | Carbon metabolism_Homo sapiens_hsa01200 | 0.74971805 |
92 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.74808462 |
93 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.74062773 |
94 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.73205453 |
95 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.73003103 |
96 | Endocytosis_Homo sapiens_hsa04144 | 0.72328549 |
97 | Platelet activation_Homo sapiens_hsa04611 | 0.71901805 |
98 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.71676878 |
99 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.71657870 |
100 | Endometrial cancer_Homo sapiens_hsa05213 | 0.71515406 |
101 | Colorectal cancer_Homo sapiens_hsa05210 | 0.69568038 |
102 | Galactose metabolism_Homo sapiens_hsa00052 | 0.69180561 |
103 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.68519449 |
104 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.68294196 |
105 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.66463593 |
106 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.66306783 |
107 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.65865038 |
108 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.64428225 |
109 | Base excision repair_Homo sapiens_hsa03410 | 0.62969061 |
110 | Thyroid cancer_Homo sapiens_hsa05216 | 0.62186207 |
111 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.62043337 |
112 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.61007891 |
113 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.60543403 |
114 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.60132834 |
115 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.60067368 |
116 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.59251764 |
117 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.59098041 |
118 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.56819462 |
119 | Adherens junction_Homo sapiens_hsa04520 | 0.56385334 |
120 | Glioma_Homo sapiens_hsa05214 | 0.55567898 |
121 | Prion diseases_Homo sapiens_hsa05020 | 0.54335416 |
122 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.54234290 |
123 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.53578481 |
124 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.51868415 |
125 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.51445106 |
126 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.50878663 |
127 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.47441954 |
128 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.46644871 |
129 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.45163552 |
130 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.43412423 |
131 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.43179275 |
132 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.42987148 |
133 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.42509711 |