OOSP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of female gonad development (GO:2000194)7.51563990
2regulation of meiosis (GO:0040020)7.10322257
3regulation of DNA methylation (GO:0044030)6.92107164
4mitotic chromosome condensation (GO:0007076)6.63339069
5female gamete generation (GO:0007292)6.44342056
6mitotic metaphase plate congression (GO:0007080)6.40174481
7retinal cone cell development (GO:0046549)6.36500903
8meiotic cell cycle (GO:0051321)6.34537814
9piRNA metabolic process (GO:0034587)6.33055580
10synapsis (GO:0007129)6.26404995
11regulation of cell maturation (GO:1903429)6.25391753
12regulation of histone H3-K27 methylation (GO:0061085)6.06064277
13negative regulation of meiosis (GO:0045835)6.00076898
14negative regulation of meiotic cell cycle (GO:0051447)5.78636412
15glycine transport (GO:0015816)5.76714179
16histone H2A monoubiquitination (GO:0035518)5.73453590
17centriole replication (GO:0007099)5.67243191
18regulation of meiotic cell cycle (GO:0051445)5.61145921
19regulation of histone H3-K9 methylation (GO:0051570)5.53359436
20positive regulation of gastrulation (GO:2000543)5.51673380
21metaphase plate congression (GO:0051310)5.39151563
22regulation of exit from mitosis (GO:0007096)5.30522402
23oocyte development (GO:0048599)5.29105952
24maturation of 5.8S rRNA (GO:0000460)5.28559219
25negative regulation of retinoic acid receptor signaling pathway (GO:0048387)5.22215870
26relaxation of smooth muscle (GO:0044557)5.22054299
27attachment of spindle microtubules to kinetochore (GO:0008608)5.20904084
28chromosome organization involved in meiosis (GO:0070192)5.11164129
29synaptonemal complex assembly (GO:0007130)5.07488429
30nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)5.05973511
31positive regulation of histone H3-K4 methylation (GO:0051571)5.04842928
32regulation of attachment of spindle microtubules to kinetochore (GO:0051988)5.01900808
33oogenesis (GO:0048477)5.00734169
34DNA damage induced protein phosphorylation (GO:0006975)4.99538972
35histone H2A ubiquitination (GO:0033522)4.95910710
36primitive streak formation (GO:0090009)4.94384012
37protein K6-linked ubiquitination (GO:0085020)4.91523263
38establishment of chromosome localization (GO:0051303)4.88430042
39regulation of meiosis I (GO:0060631)4.80387903
40positive regulation of megakaryocyte differentiation (GO:0045654)4.78677214
41mitotic sister chromatid segregation (GO:0000070)4.72610712
42labyrinthine layer development (GO:0060711)4.68777347
43regulation of sister chromatid cohesion (GO:0007063)4.68550125
44DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla4.68243737
45meiotic chromosome segregation (GO:0045132)4.64196635
46oocyte maturation (GO:0001556)4.61529665
47DNA damage response, signal transduction resulting in transcription (GO:0042772)4.60469653
48negative regulation of cAMP-mediated signaling (GO:0043951)4.59454663
49synaptonemal complex organization (GO:0070193)4.49208346
50protein localization to kinetochore (GO:0034501)4.38854417
51male meiosis (GO:0007140)4.35968830
52protein localization to chromosome, centromeric region (GO:0071459)4.33960313
53L-amino acid import (GO:0043092)4.20264865
54negative regulation of hormone biosynthetic process (GO:0032353)4.18344972
55negative regulation of hormone metabolic process (GO:0032351)4.18344972
56chromosome segregation (GO:0007059)4.15570861
57regulation of double-strand break repair via homologous recombination (GO:0010569)4.09831739
58negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)4.06164713
59translesion synthesis (GO:0019985)4.04970635
60regulation of retinoic acid receptor signaling pathway (GO:0048385)4.03696027
61somite rostral/caudal axis specification (GO:0032525)4.03422408
62neuron fate determination (GO:0048664)4.01488291
63meiotic nuclear division (GO:0007126)4.01391844
64pyrimidine-containing compound transmembrane transport (GO:0072531)4.01290379
65CENP-A containing nucleosome assembly (GO:0034080)4.01026101
66protein localization to chromosome (GO:0034502)4.00290983
67positive regulation of hematopoietic progenitor cell differentiation (GO:1901534)3.95049546
68kinetochore assembly (GO:0051382)3.93827714
69glycerophospholipid catabolic process (GO:0046475)3.92435061
70regulation of spindle organization (GO:0090224)3.92304406
71regulation of spindle checkpoint (GO:0090231)3.91086830
72chromatin assembly or disassembly (GO:0006333)3.91059302
73chromatin remodeling at centromere (GO:0031055)3.90678053
74negative regulation of DNA-templated transcription, elongation (GO:0032785)3.89214855
75negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)3.89214855
76negative regulation of cardiac muscle hypertrophy (GO:0010614)3.88659756
77positive regulation of chromosome segregation (GO:0051984)3.88157659
78regulation of acrosome reaction (GO:0060046)3.87792947
79centriole assembly (GO:0098534)3.87188208
80DNA replication-independent nucleosome organization (GO:0034724)3.84421994
81DNA replication-independent nucleosome assembly (GO:0006336)3.84421994
82regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.84392549
83genitalia morphogenesis (GO:0035112)3.83890790
84regulation of mitotic spindle checkpoint (GO:1903504)3.81279238
85regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.81279238
86sister chromatid segregation (GO:0000819)3.78999140
87regulation of mitotic spindle organization (GO:0060236)3.78985973
88DNA methylation involved in gamete generation (GO:0043046)3.78553366
89microtubule nucleation (GO:0007020)3.78519556
90kinetochore organization (GO:0051383)3.77494976
91histone exchange (GO:0043486)3.74647399
92regulation of steroid hormone secretion (GO:2000831)3.72795038
93regulation of RIG-I signaling pathway (GO:0039535)3.70164260
94type B pancreatic cell development (GO:0003323)3.64753101
95positive regulation of mitotic sister chromatid separation (GO:1901970)3.63593193
96positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.63593193
97positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.63593193
98negative regulation of histone methylation (GO:0031061)3.63496003
99dopamine biosynthetic process (GO:0042416)3.61304543
100establishment of spindle localization (GO:0051293)3.60690856
101regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.60074769
102multicellular organism reproduction (GO:0032504)3.58508648
103chaperone-mediated protein transport (GO:0072321)3.58463266
104spindle checkpoint (GO:0031577)3.55716246
105negative regulation of smooth muscle cell differentiation (GO:0051151)3.55261958
106female gonad development (GO:0008585)3.55076400
107monoubiquitinated protein deubiquitination (GO:0035520)3.53098776
108notochord development (GO:0030903)3.52899884
109positive regulation of sodium ion transmembrane transporter activity (GO:2000651)3.51899407
110mitotic nuclear envelope disassembly (GO:0007077)3.51229666
111centrosome duplication (GO:0051298)3.50498934
112regulation of chromosome segregation (GO:0051983)3.49400621
113microtubule severing (GO:0051013)3.47550653
114negative regulation of muscle hypertrophy (GO:0014741)3.45137805
115spermatid nucleus differentiation (GO:0007289)3.43334514
116sister chromatid cohesion (GO:0007062)3.40911593
117negative regulation of reproductive process (GO:2000242)3.40283556
118DNA replication checkpoint (GO:0000076)3.39271165
119myoblast migration (GO:0051451)3.34521106
120nucleus organization (GO:0006997)3.34096903
121membrane disassembly (GO:0030397)3.32934032
122nuclear envelope disassembly (GO:0051081)3.32934032
123gene silencing (GO:0016458)3.32681703
124negative regulation of execution phase of apoptosis (GO:1900118)3.31401505
125positive regulation of microtubule polymerization (GO:0031116)3.31115556
126regulation of transforming growth factor beta2 production (GO:0032909)3.30087739
127meiosis I (GO:0007127)3.28600849
128paraxial mesoderm development (GO:0048339)3.28411450
129regulation of glucocorticoid metabolic process (GO:0031943)3.26758088
130meiotic cell cycle process (GO:1903046)3.24762790
131DNA replication-dependent nucleosome assembly (GO:0006335)3.20391947
132DNA replication-dependent nucleosome organization (GO:0034723)3.20391947
133negative regulation of nuclear division (GO:0051784)3.17587637
134mitotic spindle checkpoint (GO:0071174)3.16879702
135positive regulation of histone methylation (GO:0031062)3.15455942
136negative regulation of cell division (GO:0051782)3.14629054
137positive regulation of DNA-dependent DNA replication (GO:2000105)3.13038069
138gene silencing by RNA (GO:0031047)3.12015751
139protein monoubiquitination (GO:0006513)3.11025236
140DNA alkylation (GO:0006305)3.08924625
141DNA methylation (GO:0006306)3.08924625
142snRNA transcription (GO:0009301)3.08827483
143positive regulation of granulocyte differentiation (GO:0030854)3.05070810
144base-excision repair, AP site formation (GO:0006285)3.04862995
145regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)3.03574656
146male meiosis I (GO:0007141)3.02134121
147postreplication repair (GO:0006301)3.02037424
148mitotic sister chromatid cohesion (GO:0007064)3.00126267
149cytoplasmic mRNA processing body assembly (GO:0033962)2.98926400
150negative regulation of chromosome segregation (GO:0051985)2.98906200
151positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.97973948
152negative regulation of cyclin-dependent protein serine/threonine kinase activity (GO:0045736)2.97629001
153phosphorelay signal transduction system (GO:0000160)2.95301343
154nucleotide-excision repair, DNA gap filling (GO:0006297)2.94789174
155endoderm development (GO:0007492)2.92327016
156regulation of mitotic metaphase/anaphase transition (GO:0030071)2.92246064
157regulation of chromatin silencing (GO:0031935)2.91272748
158regulation of histone H3-K4 methylation (GO:0051569)2.84911107
159relaxation of cardiac muscle (GO:0055119)2.82194690
160amino acid import (GO:0043090)2.82183197

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human9.53350165
2FOXM1_23109430_ChIP-Seq_U2OS_Human6.96978900
3FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse6.53010649
4BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse6.24345250
5FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human4.78746808
6E2F7_22180533_ChIP-Seq_HELA_Human4.05539042
7SMAD_19615063_ChIP-ChIP_OVARY_Human4.04587866
8KLF5_18264089_ChIP-ChIP_MESCs_Mouse3.90216318
9KLF4_18264089_ChIP-ChIP_MESCs_Mouse3.90216318
10KLF2_18264089_ChIP-ChIP_MESCs_Mouse3.90216318
11KAP1_22055183_ChIP-Seq_ESCs_Mouse3.84938556
12AR_21909140_ChIP-Seq_LNCAP_Human3.64580249
13MYCN_21190229_ChIP-Seq_SHEP-21N_Human3.27651453
14SALL1_21062744_ChIP-ChIP_HESCs_Human3.04120826
15NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.78292102
16HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.57960782
17GATA1_26923725_Chip-Seq_HPCs_Mouse2.48492337
18TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.35637645
19GBX2_23144817_ChIP-Seq_PC3_Human2.23594985
20E2F4_17652178_ChIP-ChIP_JURKAT_Human2.23336841
21NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.19652174
22STAT6_21828071_ChIP-Seq_BEAS2B_Human2.17719896
23RUNX1_26923725_Chip-Seq_HPCs_Mouse2.12750534
24GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.01394513
25LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.93945899
26MYC_18940864_ChIP-ChIP_HL60_Human1.93361323
27FLI1_27457419_Chip-Seq_LIVER_Mouse1.89835267
28IRF1_19129219_ChIP-ChIP_H3396_Human1.86755079
29STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.78925871
30MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.76105885
31CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.66705977
32EP300_21415370_ChIP-Seq_HL-1_Mouse1.59961094
33PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.59616332
34E2F1_21310950_ChIP-Seq_MCF-7_Human1.59510301
35NOTCH1_21737748_ChIP-Seq_TLL_Human1.58233708
36E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.57487985
37MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.55866618
38HTT_18923047_ChIP-ChIP_STHdh_Human1.54453815
39IGF1R_20145208_ChIP-Seq_DFB_Human1.48938455
40SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.48317559
41UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.46663773
42PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.44910387
43TOP2B_26459242_ChIP-Seq_MCF-7_Human1.40601670
44BP1_19119308_ChIP-ChIP_Hs578T_Human1.40340231
45IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.38944169
46CBP_20019798_ChIP-Seq_JUKART_Human1.38944169
47AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.36439574
48SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.36113871
49TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.35464954
50TP53_16413492_ChIP-PET_HCT116_Human1.35234125
51SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.35195034
52RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.34413889
53ELK4_26923725_Chip-Seq_MESODERM_Mouse1.33931869
54KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.33433014
55PCGF2_27294783_Chip-Seq_ESCs_Mouse1.33305871
56RNF2_27304074_Chip-Seq_NSC_Mouse1.32891892
57POU3F2_20337985_ChIP-ChIP_501MEL_Human1.32537863
58FOXM1_26456572_ChIP-Seq_MCF-7_Human1.30284348
59TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.28344306
60MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.27184441
61TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.25600884
62PRDM14_20953172_ChIP-Seq_ESCs_Human1.25327331
63CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.20311390
64CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.19592989
65* SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.18423236
66FUS_26573619_Chip-Seq_HEK293_Human1.17709530
67NANOG_21062744_ChIP-ChIP_HESCs_Human1.17526149
68TCF4_23295773_ChIP-Seq_U87_Human1.15537681
69GATA3_21867929_ChIP-Seq_TH1_Mouse1.12693993
70CDX2_22108803_ChIP-Seq_LS180_Human1.11685685
71CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.11563701
72CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.11418786
73GF1B_26923725_Chip-Seq_HPCs_Mouse1.11302900
74ERG_20517297_ChIP-Seq_VCAP_Human1.10709083
75P300_19829295_ChIP-Seq_ESCs_Human1.09503493
76PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.09425907
77STAT1_17558387_ChIP-Seq_HELA_Human1.08898528
78ESR1_15608294_ChIP-ChIP_MCF-7_Human1.08165962
79FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.07855964
80KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.07418845
81NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.06530267
82NANOG_18555785_Chip-Seq_ESCs_Mouse1.06375941
83STAT3_23295773_ChIP-Seq_U87_Human1.06158087
84SALL4_22934838_ChIP-ChIP_CD34+_Human1.05908241
85AUTS2_25519132_ChIP-Seq_293T-REX_Human1.05686964
86ESR1_20079471_ChIP-ChIP_T-47D_Human1.05421719
87SMAD4_21799915_ChIP-Seq_A2780_Human1.04973284
88ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.03169649
89NANOG_20526341_ChIP-Seq_ESCs_Human1.01631778
90TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00936877
91POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.00936877
92SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.99394500
93MYCN_18555785_ChIP-Seq_MESCs_Mouse0.99319014
94AR_25329375_ChIP-Seq_VCAP_Human0.98969372
95NFYA_21822215_ChIP-Seq_K562_Human0.98481841
96EWS_26573619_Chip-Seq_HEK293_Human0.96772062
97SUZ12_27294783_Chip-Seq_NPCs_Mouse0.96461055
98AHR_22903824_ChIP-Seq_MCF-7_Human0.96257766
99DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.95603144
100TP63_19390658_ChIP-ChIP_HaCaT_Human0.94784152
101PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.94617287
102TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.94424562
103E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.93935373
104CBP_21632823_ChIP-Seq_H3396_Human0.93574395
105FOXH1_21741376_ChIP-Seq_EPCs_Human0.92915348
106EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.92808545
107RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.92778688
108GATA3_26560356_Chip-Seq_TH1_Human0.92254784
109SETDB1_19884257_ChIP-Seq_MESCs_Mouse0.91335468
110TBX5_21415370_ChIP-Seq_HL-1_Mouse0.90724170
111KLF4_18555785_ChIP-Seq_MESCs_Mouse0.90419086
112GF1_26923725_Chip-Seq_HPCs_Mouse0.90041643
113PKCTHETA_26484144_Chip-Seq_BREAST_Human0.89613906
114VDR_22108803_ChIP-Seq_LS180_Human0.89581656
115SMRT_27268052_Chip-Seq_Bcells_Human0.89261280
116TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse0.87686717
117KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.87533218
118RUNX2_22187159_ChIP-Seq_PCA_Human0.87078148
119NFE2_27457419_Chip-Seq_LIVER_Mouse0.85673654
120ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.85409408
121CTBP2_25329375_ChIP-Seq_LNCAP_Human0.85037025
122EZH2_27294783_Chip-Seq_NPCs_Mouse0.84422676
123FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.83305774
124FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.82759296
125ZFP57_27257070_Chip-Seq_ESCs_Mouse0.81847726
126FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.81838185
127HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.81637407
128PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.81157997
129CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.79615509
130ARNT_22903824_ChIP-Seq_MCF-7_Human0.79399048
131TBL1_22424771_ChIP-Seq_293T_Human0.78890235
132CTCF_18555785_Chip-Seq_ESCs_Mouse0.78839163
133LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.78816157
134SMAD4_21741376_ChIP-Seq_EPCs_Human0.78548038
135KLF4_18555785_Chip-Seq_ESCs_Mouse0.77570390
136PADI4_21655091_ChIP-ChIP_MCF-7_Human0.77528188
137TAL1_26923725_Chip-Seq_HPCs_Mouse0.77430093
138ER_23166858_ChIP-Seq_MCF-7_Human0.77034301
139KDM2B_26808549_Chip-Seq_REH_Human0.76696421
140STAT3_18555785_Chip-Seq_ESCs_Mouse0.76495283
141TP63_23658742_ChIP-Seq_EP156T_Human0.76230224
142OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.75319494
143BMI1_23680149_ChIP-Seq_NPCS_Mouse0.74309574
144GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.74235333
145TBX3_20139965_ChIP-Seq_ESCs_Mouse0.73951783
146NANOG_18555785_ChIP-Seq_MESCs_Mouse0.73556661
147TBX3_20139965_ChIP-Seq_MESCs_Mouse0.73381700
148NR3C1_23031785_ChIP-Seq_PC12_Mouse0.73364974
149NANOG_19829295_ChIP-Seq_ESCs_Human0.72838289
150SOX2_19829295_ChIP-Seq_ESCs_Human0.72838289
151ZNF217_24962896_ChIP-Seq_MCF-7_Human0.72707219
152CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.72182899
153STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.71700750
154DROSHA_22980978_ChIP-Seq_HELA_Human0.70138180
155SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.69827934
156FOXA1_25329375_ChIP-Seq_VCAP_Human0.69289343
157FOXA1_27270436_Chip-Seq_PROSTATE_Human0.69289343

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003718_maternal_effect6.87055869
2MP0005451_abnormal_body_composition6.50882158
3MP0003646_muscle_fatigue5.20579335
4MP0008789_abnormal_olfactory_epithelium5.14548512
5MP0005499_abnormal_olfactory_system4.41663751
6MP0005394_taste/olfaction_phenotype4.41663751
7MP0002653_abnormal_ependyma_morphology4.23483732
8MP0002102_abnormal_ear_morphology4.11787560
9MP0003693_abnormal_embryo_hatching3.82064806
10MP0002139_abnormal_hepatobiliary_system3.52583658
11MP0005360_urolithiasis3.14580331
12MP0008877_abnormal_DNA_methylation3.13782621
13MP0005395_other_phenotype3.08787050
14MP0003077_abnormal_cell_cycle3.04654313
15MP0010094_abnormal_chromosome_stability3.03693048
16MP0002138_abnormal_hepatobiliary_system3.01456289
17MP0003111_abnormal_nucleus_morphology3.01343595
18MP0010030_abnormal_orbit_morphology2.88565269
19MP0003699_abnormal_female_reproductive2.87642007
20MP0001119_abnormal_female_reproductive2.74941734
21MP0002234_abnormal_pharynx_morphology2.67592773
22MP0005408_hypopigmentation2.62476021
23MP0004957_abnormal_blastocyst_morpholog2.48247423
24MP0000653_abnormal_sex_gland2.17107329
25MP0001929_abnormal_gametogenesis2.16713729
26MP0003183_abnormal_peptide_metabolism2.16638344
27MP0005410_abnormal_fertilization2.15068587
28MP0003879_abnormal_hair_cell2.11665560
29MP0002210_abnormal_sex_determination1.99228074
30MP0004264_abnormal_extraembryonic_tissu1.90600955
31MP0006292_abnormal_olfactory_placode1.81578051
32MP0003787_abnormal_imprinting1.80851070
33MP0001529_abnormal_vocalization1.79734351
34MP0002160_abnormal_reproductive_system1.75358908
35MP0003937_abnormal_limbs/digits/tail_de1.71054847
36MP0003123_paternal_imprinting1.70686122
37MP0001984_abnormal_olfaction1.66933094
38MP0004185_abnormal_adipocyte_glucose1.59654717
39MP0003121_genomic_imprinting1.54075802
40MP0008932_abnormal_embryonic_tissue1.53255253
41MP0000579_abnormal_nail_morphology1.52726220
42MP0005310_abnormal_salivary_gland1.49944318
43MP0002249_abnormal_larynx_morphology1.49666074
44MP0002161_abnormal_fertility/fecundity1.48747933
45MP0010234_abnormal_vibrissa_follicle1.48217753
46MP0003252_abnormal_bile_duct1.47294692
47MP0000350_abnormal_cell_proliferation1.45351608
48MP0000566_synostosis1.44954158
49MP0000762_abnormal_tongue_morphology1.43607831
50MP0008007_abnormal_cellular_replicative1.43141394
51MP0001293_anophthalmia1.40959465
52MP0001915_intracranial_hemorrhage1.38029614
53MP0004510_myositis1.34604119
54MP0001145_abnormal_male_reproductive1.34551696
55MP0002085_abnormal_embryonic_tissue1.29267075
56MP0000639_abnormal_adrenal_gland1.28834428
57MP0001730_embryonic_growth_arrest1.27391099
58MP0010368_abnormal_lymphatic_system1.26757396
59MP0001697_abnormal_embryo_size1.16165767
60MP0002233_abnormal_nose_morphology1.15423652
61MP0000462_abnormal_digestive_system1.12977058
62MP0001905_abnormal_dopamine_level1.12383965
63MP0002019_abnormal_tumor_incidence1.07146750
64MP0005085_abnormal_gallbladder_physiolo1.06913248
65MP0002084_abnormal_developmental_patter1.06169100
66MP0003315_abnormal_perineum_morphology1.05459201
67MP0005646_abnormal_pituitary_gland1.03889295
68MP0008260_abnormal_autophagy1.03528902
69MP0003950_abnormal_plasma_membrane1.02804009
70MP0002877_abnormal_melanocyte_morpholog0.98041884
71MP0001346_abnormal_lacrimal_gland0.97136334
72MP0002796_impaired_skin_barrier0.96660006
73MP0005380_embryogenesis_phenotype0.95086277
74MP0001672_abnormal_embryogenesis/_devel0.95086277
75MP0005389_reproductive_system_phenotype0.94140100
76MP0001849_ear_inflammation0.94136022
77MP0001986_abnormal_taste_sensitivity0.87693611
78MP0003890_abnormal_embryonic-extraembry0.85797826
79MP0004142_abnormal_muscle_tone0.82763771
80MP0003453_abnormal_keratinocyte_physiol0.81620973
81MP0001851_eye_inflammation0.81168733
82MP0005647_abnormal_sex_gland0.79835886
83MP0003119_abnormal_digestive_system0.78054227
84MP0000490_abnormal_crypts_of0.76354133
85MP0005621_abnormal_cell_physiology0.75814910
86MP0008057_abnormal_DNA_replication0.75752363
87MP0002272_abnormal_nervous_system0.74247035
88MP0010386_abnormal_urinary_bladder0.73621392
89MP0004145_abnormal_muscle_electrophysio0.71836017
90MP0000427_abnormal_hair_cycle0.70523356
91MP0003698_abnormal_male_reproductive0.70235196
92MP0003755_abnormal_palate_morphology0.68882309
93MP0009840_abnormal_foam_cell0.68457493
94MP0006072_abnormal_retinal_apoptosis0.68044854
95MP0003868_abnormal_feces_composition0.68011273
96MP0005551_abnormal_eye_electrophysiolog0.67870345
97MP0006276_abnormal_autonomic_nervous0.66239661
98MP0008058_abnormal_DNA_repair0.65935472
99MP0001324_abnormal_eye_pigmentation0.65123533
100MP0005501_abnormal_skin_physiology0.64931949
101MP0001666_abnormal_nutrient_absorption0.64902055
102MP0006138_congestive_heart_failure0.60747482
103MP0003763_abnormal_thymus_physiology0.60351309
104MP0005187_abnormal_penis_morphology0.60216704
105MP0003984_embryonic_growth_retardation0.59719898
106MP0000049_abnormal_middle_ear0.59268732
107MP0002080_prenatal_lethality0.58856863
108MP0002928_abnormal_bile_duct0.57994528
109MP0002088_abnormal_embryonic_growth/wei0.56340171
110MP0002090_abnormal_vision0.56259228
111MP0001502_abnormal_circadian_rhythm0.55171028
112MP0002086_abnormal_extraembryonic_tissu0.55047519
113MP0002177_abnormal_outer_ear0.54700863
114MP0005075_abnormal_melanosome_morpholog0.54303526
115MP0009250_abnormal_appendicular_skeleto0.54242347
116MP0000631_abnormal_neuroendocrine_gland0.54049596
117MP0002932_abnormal_joint_morphology0.52839327
118MP0003705_abnormal_hypodermis_morpholog0.52623567
119MP0005503_abnormal_tendon_morphology0.52256714
120MP0003861_abnormal_nervous_system0.52160989
121MP0003941_abnormal_skin_development0.52108156
122MP0004084_abnormal_cardiac_muscle0.50698220
123MP0010307_abnormal_tumor_latency0.49632123
124MP0005384_cellular_phenotype0.49488569
125MP0001756_abnormal_urination0.48763637
126MP0003656_abnormal_erythrocyte_physiolo0.47426787
127MP0002163_abnormal_gland_morphology0.47377201
128MP0002168_other_aberrant_phenotype0.46205634
129MP0001963_abnormal_hearing_physiology0.46018809
130MP0001664_abnormal_digestion0.46005242
131MP0000678_abnormal_parathyroid_gland0.45894806
132MP0002116_abnormal_craniofacial_bone0.45564148
133MP0010678_abnormal_skin_adnexa0.43471424
134MP0002638_abnormal_pupillary_reflex0.42782576
135MP0001919_abnormal_reproductive_system0.42486026
136MP0009697_abnormal_copulation0.41439713
137MP0002751_abnormal_autonomic_nervous0.41108475
138MP0002396_abnormal_hematopoietic_system0.40958222
139MP0000613_abnormal_salivary_gland0.40572465
140MP0002089_abnormal_postnatal_growth/wei0.40223518
141MP0003935_abnormal_craniofacial_develop0.40036431
142MP0003632_abnormal_nervous_system0.39957637
143MP0009384_cardiac_valve_regurgitation0.39562610
144MP0001944_abnormal_pancreas_morphology0.39109202
145MP0000377_abnormal_hair_follicle0.39037263
146MP0000313_abnormal_cell_death0.38908748
147MP0000733_abnormal_muscle_development0.38823472
148MP0004043_abnormal_pH_regulation0.36473145
149MP0009780_abnormal_chondrocyte_physiolo0.33993567
150MP0000026_abnormal_inner_ear0.33929640
151MP0003136_yellow_coat_color0.32976700
152MP0002127_abnormal_cardiovascular_syste0.31666044
153MP0003195_calcinosis0.29940289
154MP0000428_abnormal_craniofacial_morphol0.29901250
155MP0002735_abnormal_chemical_nociception0.27270891
156MP0002873_normal_phenotype0.27048341

Predicted human phenotypes

RankGene SetZ-score
1Male infertility (HP:0003251)8.41791492
2Cholecystitis (HP:0001082)5.61479514
3Abnormal gallbladder physiology (HP:0012438)5.61479514
4Birth length less than 3rd percentile (HP:0003561)5.34748127
5Breast hypoplasia (HP:0003187)4.88110240
6Papillary thyroid carcinoma (HP:0002895)4.73306897
7Osteomalacia (HP:0002749)4.72775530
8Abdominal situs inversus (HP:0003363)4.65238766
9Abnormality of abdominal situs (HP:0011620)4.65238766
10Chromsome breakage (HP:0040012)4.58209480
11Absent septum pellucidum (HP:0001331)4.39550382
12Septo-optic dysplasia (HP:0100842)4.38622831
13Enlarged penis (HP:0000040)4.36832428
14Short tibia (HP:0005736)4.31987447
15Adrenal hypoplasia (HP:0000835)4.25573003
16Hypophosphatemic rickets (HP:0004912)4.09821229
17Azoospermia (HP:0000027)4.08676220
18Median cleft lip (HP:0000161)4.00769794
19Chromosomal breakage induced by crosslinking agents (HP:0003221)3.97027178
20Abnormality of the septum pellucidum (HP:0007375)3.88804770
21Aplasia/Hypoplasia of the tibia (HP:0005772)3.85726006
22Gonadotropin excess (HP:0000837)3.82684613
23Patellar aplasia (HP:0006443)3.77312289
24Cortical dysplasia (HP:0002539)3.76130523
25Facial hemangioma (HP:0000329)3.75545655
26Stillbirth (HP:0003826)3.75240491
27Shawl scrotum (HP:0000049)3.75125369
28Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)3.64888394
29Fair hair (HP:0002286)3.64860978
30Abnormality of the labia minora (HP:0012880)3.59535904
31Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.48191404
32Capillary hemangiomas (HP:0005306)3.48103473
33Flat capital femoral epiphysis (HP:0003370)3.45680924
34Aplasia/Hypoplasia of the patella (HP:0006498)3.45227076
35Ankle contracture (HP:0006466)3.43557123
36Premature ovarian failure (HP:0008209)3.35636484
37Elevated circulating parathyroid hormone (PTH) level (HP:0003165)3.30823665
38Secondary amenorrhea (HP:0000869)3.24683776
39Infertility (HP:0000789)3.21563439
40Breast aplasia (HP:0100783)3.10590190
41Conjunctival telangiectasia (HP:0000524)3.09859329
42Aplasia/Hypoplasia of the breasts (HP:0010311)3.07786262
43Arterial tortuosity (HP:0005116)3.06861499
44Abnormal spermatogenesis (HP:0008669)3.06555224
45Abnormality of lateral ventricle (HP:0030047)2.96297737
46Urethral obstruction (HP:0000796)2.94443373
47Sensory axonal neuropathy (HP:0003390)2.92025278
48Abnormality of the fingertips (HP:0001211)2.89286148
49Acute myeloid leukemia (HP:0004808)2.87034701
50Aplasia/Hypoplasia of the sternum (HP:0006714)2.83087199
51Intrahepatic cholestasis (HP:0001406)2.80753060
52Impulsivity (HP:0100710)2.77684706
53Generalized hypopigmentation of hair (HP:0011358)2.71483961
54Abnormality of chromosome segregation (HP:0002916)2.70061162
55Pulmonary fibrosis (HP:0002206)2.67710487
56Sandal gap (HP:0001852)2.67603677
57Chronic bronchitis (HP:0004469)2.67408066
58Abnormality of chromosome stability (HP:0003220)2.64542237
59Abnormal lung lobation (HP:0002101)2.63736387
60Vascular tortuosity (HP:0004948)2.62786577
61Abnormal biliary tract physiology (HP:0012439)2.56378510
62Bile duct proliferation (HP:0001408)2.56378510
63Metaphyseal irregularity (HP:0003025)2.55968934
64Shallow orbits (HP:0000586)2.55963611
65Spondylolisthesis (HP:0003302)2.55130150
66Insulin-resistant diabetes mellitus (HP:0000831)2.53754856
67Muscle stiffness (HP:0003552)2.52620930
68Proximal tubulopathy (HP:0000114)2.51892538
69Oligodactyly (hands) (HP:0001180)2.50766274
70Spinal cord compression (HP:0002176)2.48709840
71Hypergonadotropic hypogonadism (HP:0000815)2.46906940
72Rhabdomyosarcoma (HP:0002859)2.45620431
73Bicornuate uterus (HP:0000813)2.45392070
74Abnormality of the vasculature of the conjunctiva (HP:0008054)2.45076025
75Thyroid carcinoma (HP:0002890)2.43540360
76Abnormality of aromatic amino acid family metabolism (HP:0004338)2.42788000
77Hip contracture (HP:0003273)2.42123205
78Deep venous thrombosis (HP:0002625)2.40436335
79Maternal diabetes (HP:0009800)2.37523284
80Heterotopia (HP:0002282)2.36946488
81Aplasia/Hypoplasia of the tongue (HP:0010295)2.34099004
82Overlapping toe (HP:0001845)2.32331642
83Rib fusion (HP:0000902)2.30449587
84Hydroureter (HP:0000072)2.28615089
85Abnormal ciliary motility (HP:0012262)2.28312860
86Prostate neoplasm (HP:0100787)2.26397108
87Fibular aplasia (HP:0002990)2.26390256
88Limb hypertonia (HP:0002509)2.24888245
89Aplasia/Hypoplasia of the uvula (HP:0010293)2.24134438
90Steatorrhea (HP:0002570)2.21136407
91Abnormality of the preputium (HP:0100587)2.20684955
92Lip pit (HP:0100267)2.20671963
93Malnutrition (HP:0004395)2.17522677
94Generalized aminoaciduria (HP:0002909)2.16897189
95Supernumerary spleens (HP:0009799)2.16770125
96Oligodactyly (HP:0012165)2.16612372
97Aplasia/Hypoplasia involving the musculature (HP:0001460)2.15741597
98Primary amenorrhea (HP:0000786)2.14394556
99Small intestinal stenosis (HP:0012848)2.10589555
100Duodenal stenosis (HP:0100867)2.10589555
101Abnormality of the fovea (HP:0000493)2.09646391
102Rhinitis (HP:0012384)2.08510592
103Myelodysplasia (HP:0002863)2.08501637
104Abnormality of the proximal phalanges of the hand (HP:0009834)2.08143836
105Meckel diverticulum (HP:0002245)2.07314637
106Carpal bone hypoplasia (HP:0001498)2.06877387
107Hypokinesia (HP:0002375)2.06702058
108Spontaneous abortion (HP:0005268)2.05853359
109Oral leukoplakia (HP:0002745)2.05535208
110Hypoplastic iliac wings (HP:0002866)2.05347534
111Loss of speech (HP:0002371)2.05084110
112Pancreatic fibrosis (HP:0100732)2.04644853
113Nonprogressive disorder (HP:0003680)2.04490434
114Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.04282682
115Aplastic anemia (HP:0001915)2.03942220
116Skin pits (HP:0100276)2.03754715
117Absent hand (HP:0004050)2.03324558
118Diminished motivation (HP:0000745)2.03116692
119Apathy (HP:0000741)2.02730623
120Bundle branch block (HP:0011710)2.02002009
121Absent radius (HP:0003974)2.01827356
122Absent forearm bone (HP:0003953)1.99955674
123Aplasia involving forearm bones (HP:0009822)1.99955674
124Congenital sensorineural hearing impairment (HP:0008527)1.99942420
125Fetal akinesia sequence (HP:0001989)1.98804603
126Amniotic constriction ring (HP:0009775)1.97985323
127Abnormality of placental membranes (HP:0011409)1.97985323
128Cystic hygroma (HP:0000476)1.97903246
129Short thumb (HP:0009778)1.95681590
130Cranial hyperostosis (HP:0004437)1.95198586
131Abnormality of the epiphysis of the femoral head (HP:0010574)1.94067784
132Nephroblastoma (Wilms tumor) (HP:0002667)1.91394579
133Aplasia/Hypoplasia of the macula (HP:0008059)1.91046000
134Sloping forehead (HP:0000340)1.91029026
135Abnormality of the ileum (HP:0001549)1.90935301
136Complete atrioventricular canal defect (HP:0001674)1.90292534
137Anomalous pulmonary venous return (HP:0010772)1.88814613
138Abnormality of monocarboxylic acid metabolism (HP:0010996)1.88779430
139Aplasia/Hypoplasia of the fovea (HP:0008060)1.88497401
140Hypoplasia of the fovea (HP:0007750)1.88497401
141Megaloblastic anemia (HP:0001889)1.88468444
142Anterior segment dysgenesis (HP:0007700)1.87713538
143Clitoromegaly (HP:0000057)1.86390925
144Wrist flexion contracture (HP:0001239)1.86038023
145Abnormality of small intestinal villus morphology (HP:0011472)1.84909402
146Villous atrophy (HP:0011473)1.84909402
147Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.84482241
148Short 1st metacarpal (HP:0010034)1.84482241
149Ectopic kidney (HP:0000086)1.83973462
150Abnormality of the labia (HP:0000058)1.83137304
151Postural tremor (HP:0002174)1.82848673
152Underdeveloped supraorbital ridges (HP:0009891)1.82336804
153Abnormality of the phalanges of the hallux (HP:0010057)1.81890014
154Lower limb hyperreflexia (HP:0002395)1.81871274
155Cafe-au-lait spot (HP:0000957)1.81802060
156Dysdiadochokinesis (HP:0002075)1.81286999
157Abnormality of the femoral head (HP:0003368)1.81127923
158Hypohidrosis (HP:0000966)1.80967674
159Neoplasm of the oral cavity (HP:0100649)1.80775798
160Abnormality of calcium-phosphate metabolism (HP:0100530)1.78991685
161Abnormality of the intervertebral disk (HP:0005108)1.78939262
162Midline defect of the nose (HP:0004122)1.78377627
163Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.77918426
164Abnormality of alanine metabolism (HP:0010916)1.77918426
165Hyperalaninemia (HP:0003348)1.77918426
166Posterior embryotoxon (HP:0000627)1.77784419
167Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.77021301
168Embryonal renal neoplasm (HP:0011794)1.75875935

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MOS4.90499455
2LATS14.74907989
3BMPR24.57370270
4TAOK34.47378295
5LATS24.12151867
6MAP3K64.08360000
7KSR23.37119170
8STK38L3.25157623
9NEK63.14164195
10MAP3K92.81821133
11PLK42.76271643
12MET2.66341380
13TTK2.48400983
14MAP3K132.39654858
15ERBB42.33970769
16EIF2AK32.21406407
17ARAF2.18524670
18CDC72.18512406
19MUSK2.15449683
20RAF12.08411342
21TAOK11.99698570
22BRAF1.99593161
23CDK81.96805741
24PRKCI1.71514300
25EEF2K1.71392793
26ZAK1.63475386
27DYRK21.56907275
28PRKD31.55749684
29STK31.50330068
30CDK91.46601312
31KSR11.37123564
32PAK61.36464595
33NEK21.34914446
34BUB11.31319116
35MELK1.30141752
36STK101.19864787
37MAPKAPK31.16351786
38CHEK21.15404628
39MST41.15007747
40MAP3K41.14566544
41TIE11.13715483
42TNIK1.13211409
43STK391.08788986
44PLK11.03868390
45STK381.00402578
46ABL20.90426179
47MAPK130.87890785
48PIM10.87660886
49MAP3K80.83190804
50RET0.81402920
51CSNK1G10.76390277
52MAP2K70.75411697
53PRKD20.74494105
54TRIM280.73184599
55DMPK0.69490546
56PINK10.69430562
57TYRO30.68168007
58BMPR1B0.67989255
59AURKB0.62009726
60MARK30.59609500
61CSNK1G20.59117196
62ACVR1B0.58377403
63CDK120.57617448
64NLK0.55936858
65LMTK20.55305585
66MAPKAPK50.53150305
67MAP2K40.52372900
68CSNK1G30.51634426
69AURKA0.51574390
70PRKG10.51272459
71PRKAA10.50709167
72HIPK20.49294353
73TNK20.49135729
74OXSR10.48768785
75NEK10.45814157
76NTRK30.44985713
77PRKAA20.41838382
78SGK20.41140979
79MAP3K50.40744311
80TGFBR10.39061466
81MARK20.38024795
82PKN10.36851117
83CSNK1A1L0.36157173
84STK240.35755777
85PLK30.34117887
86CDK70.33857244
87LRRK20.32849562
88CHUK0.32463735
89WNK10.31759851
90MAP3K10.31705994
91SGK4940.31240410
92SGK2230.31240410
93CDK40.30639763
94CHEK10.28927549
95ATM0.28666056
96EIF2AK20.28493525
97EGFR0.27253602
98MAPK110.26988576
99PRKACA0.26940072
100CDK30.25758737
101ABL10.25684005
102KIT0.24646860
103EIF2AK10.23348876
104CAMK2A0.22153343
105MAP2K10.21940833
106CDK50.21417484
107CDK10.20945737
108PTK20.20806314
109PRKACB0.20795608
110JAK30.20535808
111TRPM70.20062875
112TLK10.19336839
113PRKCZ0.19040631
114CDK20.18258692
115RPS6KB20.18214198
116NUAK10.16701009
117NTRK20.16594793
118BRSK10.16137385
119CSNK1E0.15521752
120PDK10.13973753
121PAK10.13678658
122CSNK1D0.13409766
123JAK20.12965938
124TRIB30.12530574
125SGK30.12231967
126CDK11A0.11648658
127SRPK10.10964550
128VRK10.10810107
129PBK0.10176082
130EPHA30.10041806
131AKT20.09864017
132CDK190.09569305
133CDK180.09366254
134NEK90.08422138
135PLK20.07026470
136ATR0.07016695
137MAPK10.06193178
138BRSK20.04169745
139AKT10.04040633
140CDK150.03826232

Predicted pathways (KEGG)

RankGene SetZ-score
1Cell cycle_Homo sapiens_hsa041104.37359012
2Caffeine metabolism_Homo sapiens_hsa002324.15393907
3Ovarian steroidogenesis_Homo sapiens_hsa049133.97448771
4RNA degradation_Homo sapiens_hsa030183.83767941
5Basal transcription factors_Homo sapiens_hsa030223.69050577
6Oocyte meiosis_Homo sapiens_hsa041143.07034714
7Circadian rhythm_Homo sapiens_hsa047103.00307896
8Vitamin B6 metabolism_Homo sapiens_hsa007502.86827772
9Progesterone-mediated oocyte maturation_Homo sapiens_hsa049142.70169645
10Pancreatic cancer_Homo sapiens_hsa052122.36919045
11Olfactory transduction_Homo sapiens_hsa047402.18740403
12alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.13302957
13RNA polymerase_Homo sapiens_hsa030202.12581753
14Linoleic acid metabolism_Homo sapiens_hsa005912.11019558
15TGF-beta signaling pathway_Homo sapiens_hsa043501.93676538
16Ether lipid metabolism_Homo sapiens_hsa005651.91183972
17Homologous recombination_Homo sapiens_hsa034401.81660556
18p53 signaling pathway_Homo sapiens_hsa041151.79665127
19Fanconi anemia pathway_Homo sapiens_hsa034601.77911422
20Base excision repair_Homo sapiens_hsa034101.76838447
21Dorso-ventral axis formation_Homo sapiens_hsa043201.72114004
22RNA transport_Homo sapiens_hsa030131.69041480
23GnRH signaling pathway_Homo sapiens_hsa049121.59315327
24MicroRNAs in cancer_Homo sapiens_hsa052061.49698557
25DNA replication_Homo sapiens_hsa030301.49177589
26Colorectal cancer_Homo sapiens_hsa052101.42660948
27Nicotine addiction_Homo sapiens_hsa050331.42324429
28Non-homologous end-joining_Homo sapiens_hsa034501.42204413
29Prolactin signaling pathway_Homo sapiens_hsa049171.41995919
30Nucleotide excision repair_Homo sapiens_hsa034201.34866439
31Cysteine and methionine metabolism_Homo sapiens_hsa002701.34277474
32mRNA surveillance pathway_Homo sapiens_hsa030151.32945345
33Choline metabolism in cancer_Homo sapiens_hsa052311.32311432
34Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.30183828
35Folate biosynthesis_Homo sapiens_hsa007901.29063272
36Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.28116631
37SNARE interactions in vesicular transport_Homo sapiens_hsa041301.12517468
38Renal cell carcinoma_Homo sapiens_hsa052111.09137262
39VEGF signaling pathway_Homo sapiens_hsa043701.09079985
40Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.07876780
41Synaptic vesicle cycle_Homo sapiens_hsa047211.07353130
42mTOR signaling pathway_Homo sapiens_hsa041501.03663096
43ABC transporters_Homo sapiens_hsa020101.00745026
44Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.98001413
45Vitamin digestion and absorption_Homo sapiens_hsa049770.94025355
46Phototransduction_Homo sapiens_hsa047440.93138028
47Adherens junction_Homo sapiens_hsa045200.91374241
48Long-term depression_Homo sapiens_hsa047300.90757379
49Endometrial cancer_Homo sapiens_hsa052130.87969162
50Notch signaling pathway_Homo sapiens_hsa043300.87467479
51Hippo signaling pathway_Homo sapiens_hsa043900.86477777
52FoxO signaling pathway_Homo sapiens_hsa040680.83892387
53Thyroid cancer_Homo sapiens_hsa052160.83502093
54Morphine addiction_Homo sapiens_hsa050320.82927747
55Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.81049940
56Glycerophospholipid metabolism_Homo sapiens_hsa005640.79680098
57Bladder cancer_Homo sapiens_hsa052190.79167908
58Fatty acid elongation_Homo sapiens_hsa000620.78645947
59GABAergic synapse_Homo sapiens_hsa047270.77367368
60Bile secretion_Homo sapiens_hsa049760.75559213
61Thyroid hormone signaling pathway_Homo sapiens_hsa049190.73323055
62Pyrimidine metabolism_Homo sapiens_hsa002400.73092494
63Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.72014453
64Non-small cell lung cancer_Homo sapiens_hsa052230.71770837
65Chronic myeloid leukemia_Homo sapiens_hsa052200.70123509
66Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.69797259
67Mismatch repair_Homo sapiens_hsa034300.69559280
68Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.68114336
69Ras signaling pathway_Homo sapiens_hsa040140.68044612
70Small cell lung cancer_Homo sapiens_hsa052220.67403247
71HTLV-I infection_Homo sapiens_hsa051660.67276020
72Phospholipase D signaling pathway_Homo sapiens_hsa040720.65354705
73Longevity regulating pathway - mammal_Homo sapiens_hsa042110.63597628
74Viral carcinogenesis_Homo sapiens_hsa052030.61725671
75MAPK signaling pathway_Homo sapiens_hsa040100.60708967
76Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.60346751
77Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.59614741
78Phosphatidylinositol signaling system_Homo sapiens_hsa040700.59146391
79Glycosaminoglycan degradation_Homo sapiens_hsa005310.58762304
80Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.58417860
81Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.57958523
82Hepatitis B_Homo sapiens_hsa051610.57685636
83Estrogen signaling pathway_Homo sapiens_hsa049150.53232539
84Purine metabolism_Homo sapiens_hsa002300.50638523
85Prostate cancer_Homo sapiens_hsa052150.49921458
86Shigellosis_Homo sapiens_hsa051310.46327394
87Herpes simplex infection_Homo sapiens_hsa051680.44289396
88Glioma_Homo sapiens_hsa052140.43876420
89Propanoate metabolism_Homo sapiens_hsa006400.43173834
90ErbB signaling pathway_Homo sapiens_hsa040120.42402606
91Wnt signaling pathway_Homo sapiens_hsa043100.39477359
92Regulation of actin cytoskeleton_Homo sapiens_hsa048100.38741553
93Regulation of autophagy_Homo sapiens_hsa041400.37211416
94Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.37166948
95Sphingolipid signaling pathway_Homo sapiens_hsa040710.34622615
96Taste transduction_Homo sapiens_hsa047420.33630573
97Arachidonic acid metabolism_Homo sapiens_hsa005900.33486316
98Melanoma_Homo sapiens_hsa052180.33090336
99Influenza A_Homo sapiens_hsa051640.31079729
100Serotonergic synapse_Homo sapiens_hsa047260.30746709
101cGMP-PKG signaling pathway_Homo sapiens_hsa040220.30076558
102Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.29684965
103Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.29599402
104Glutamatergic synapse_Homo sapiens_hsa047240.27555900
105Vascular smooth muscle contraction_Homo sapiens_hsa042700.26976895
106cAMP signaling pathway_Homo sapiens_hsa040240.26620057
107Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.26092209
108Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.25623742
109Transcriptional misregulation in cancer_Homo sapiens_hsa052020.24823543
110Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.24533534
111Epstein-Barr virus infection_Homo sapiens_hsa051690.24270711
112Sphingolipid metabolism_Homo sapiens_hsa006000.23650895
113Pathways in cancer_Homo sapiens_hsa052000.22645745
114Drug metabolism - other enzymes_Homo sapiens_hsa009830.22458283
115Tight junction_Homo sapiens_hsa045300.22032164
116Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.18824513
117Inositol phosphate metabolism_Homo sapiens_hsa005620.15643642
118TNF signaling pathway_Homo sapiens_hsa046680.15094872
119Arginine and proline metabolism_Homo sapiens_hsa003300.15010222
120Oxytocin signaling pathway_Homo sapiens_hsa049210.14417455
121Gap junction_Homo sapiens_hsa045400.12837942
122Long-term potentiation_Homo sapiens_hsa047200.12179744
123Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.11967823
124Jak-STAT signaling pathway_Homo sapiens_hsa046300.11542331
125Hedgehog signaling pathway_Homo sapiens_hsa043400.11100543
126Protein digestion and absorption_Homo sapiens_hsa049740.10023288
127Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.08683452
128Phagosome_Homo sapiens_hsa041450.08555953
129Pyruvate metabolism_Homo sapiens_hsa006200.07212687
130Cardiac muscle contraction_Homo sapiens_hsa042600.07108624
131Huntingtons disease_Homo sapiens_hsa050160.06208439
132B cell receptor signaling pathway_Homo sapiens_hsa046620.04426998
133Cholinergic synapse_Homo sapiens_hsa047250.02061493
134Dopaminergic synapse_Homo sapiens_hsa047280.00353294

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