OR10AA1P

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1detection of molecule of bacterial origin (GO:0032490)5.75561186
2regulation of B cell receptor signaling pathway (GO:0050855)5.51440186
3modulation by symbiont of host immune response (GO:0052553)5.20539898
4positive regulation by symbiont of host defense response (GO:0052509)5.20539898
5modulation by symbiont of host defense response (GO:0052031)5.20539898
6modulation by organism of immune response of other organism involved in symbiotic interaction (GO:005.20539898
7modulation by organism of defense response of other organism involved in symbiotic interaction (GO:05.20539898
8positive regulation by organism of defense response of other organism involved in symbiotic interact5.20539898
9pyrimidine-containing compound transmembrane transport (GO:0072531)4.95279285
10microglial cell activation (GO:0001774)4.92150597
11negative regulation of cAMP-mediated signaling (GO:0043951)4.75117489
12positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)4.70430656
13fucose catabolic process (GO:0019317)4.15147229
14L-fucose metabolic process (GO:0042354)4.15147229
15L-fucose catabolic process (GO:0042355)4.15147229
16positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)4.04707284
17regulation of interferon-beta biosynthetic process (GO:0045357)4.02748076
18positive regulation of gamma-delta T cell activation (GO:0046645)4.00835664
19macrophage activation involved in immune response (GO:0002281)3.90286716
20negative regulation of cell killing (GO:0031342)3.85730435
21negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.85730435
22macrophage activation (GO:0042116)3.83357210
23neutrophil mediated immunity (GO:0002446)3.80677051
24antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.75469584
25detection of external biotic stimulus (GO:0098581)3.74460526
26protein K11-linked deubiquitination (GO:0035871)3.73726136
27negative T cell selection (GO:0043383)3.71275182
28regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.55825761
29myeloid leukocyte mediated immunity (GO:0002444)3.51741836
30regulation of interleukin-12 biosynthetic process (GO:0045075)3.51490743
31opioid receptor signaling pathway (GO:0038003)3.51257316
32water-soluble vitamin biosynthetic process (GO:0042364)3.49974281
33protein targeting to Golgi (GO:0000042)3.47896397
34regulation of nitric-oxide synthase biosynthetic process (GO:0051769)3.46118759
35negative regulation of interleukin-12 production (GO:0032695)3.42108258
36regulation of interleukin-6 biosynthetic process (GO:0045408)3.39560008
37establishment of protein localization to Golgi (GO:0072600)3.38247809
38positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.37382682
39positive regulation of interleukin-8 biosynthetic process (GO:0045416)3.37215516
40response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.35996389
41response to host immune response (GO:0052572)3.35996389
42positive regulation of toll-like receptor signaling pathway (GO:0034123)3.35116043
43cellular extravasation (GO:0045123)3.32240899
44neural tube formation (GO:0001841)3.29756427
45regulation of gamma-delta T cell differentiation (GO:0045586)3.28721102
46detection of biotic stimulus (GO:0009595)3.24374897
47neutrophil activation involved in immune response (GO:0002283)3.23899125
48retrograde transport, vesicle recycling within Golgi (GO:0000301)3.20859648
49negative thymic T cell selection (GO:0045060)3.19051173
50dopamine transport (GO:0015872)3.15372522
51pantothenate metabolic process (GO:0015939)3.13054486
52regulation of gamma-delta T cell activation (GO:0046643)3.10493039
53negative regulation of B cell proliferation (GO:0030889)3.06900248
54phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.06516157
55T-helper 1 type immune response (GO:0042088)3.05747019
56regulation of cilium movement (GO:0003352)3.05159522
57hepatocyte apoptotic process (GO:0097284)3.02838075
58NAD biosynthetic process (GO:0009435)3.01567586
59negative regulation of T cell mediated immunity (GO:0002710)3.01382755
60defense response to protozoan (GO:0042832)2.97831908
61positive T cell selection (GO:0043368)2.95770872
62positive regulation of T cell mediated cytotoxicity (GO:0001916)2.95097994
63positive regulation of interferon-alpha production (GO:0032727)2.90691391
64response to host (GO:0075136)2.88948445
65response to host defenses (GO:0052200)2.88948445
66response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.88948445
67negative regulation of lymphocyte mediated immunity (GO:0002707)2.88728344
68piRNA metabolic process (GO:0034587)2.86884318
69negative regulation of cytosolic calcium ion concentration (GO:0051481)2.86768938
70negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642)2.86096017
71vitamin transmembrane transport (GO:0035461)2.84548994
72behavioral response to nicotine (GO:0035095)2.83584441
73positive regulation of interleukin-1 beta secretion (GO:0050718)2.82677354
74response to interleukin-15 (GO:0070672)2.82541166
75regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.81084286
76detection of other organism (GO:0098543)2.79402038
77interferon-gamma production (GO:0032609)2.79371214
78activated T cell proliferation (GO:0050798)2.78884790
79regulation of ER to Golgi vesicle-mediated transport (GO:0060628)2.77995622
80monoubiquitinated protein deubiquitination (GO:0035520)2.74606273
81regulation of interferon-alpha production (GO:0032647)2.74467990
82positive regulation of interferon-beta production (GO:0032728)2.73624461
83protein localization to Golgi apparatus (GO:0034067)2.69573720
84myeloid cell activation involved in immune response (GO:0002275)2.69063144
85negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.67390076
86regulation of T cell mediated cytotoxicity (GO:0001914)2.65172925
87striated muscle atrophy (GO:0014891)2.63848597
88adult feeding behavior (GO:0008343)2.63041177
89cellular response to interleukin-15 (GO:0071350)2.63003818
90necroptotic process (GO:0070266)2.62674263
91behavioral response to ethanol (GO:0048149)2.62637970
92positive regulation of interleukin-1 secretion (GO:0050716)2.62294846
93regulation of alpha-beta T cell proliferation (GO:0046640)2.62112218
94cellular ketone body metabolic process (GO:0046950)2.61746231
95negative regulation of glycoprotein biosynthetic process (GO:0010561)2.61669345
96neutrophil activation (GO:0042119)2.60054105
97negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)2.59979469
98regulation of memory T cell differentiation (GO:0043380)2.59705139
99production of molecular mediator involved in inflammatory response (GO:0002532)2.55747947
100alkaloid metabolic process (GO:0009820)2.55288729

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human4.12107125
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.36165821
3IRF8_21731497_ChIP-ChIP_J774_Mouse3.18413401
4SMAD_19615063_ChIP-ChIP_OVARY_Human3.15070940
5STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.02143750
6BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.80868104
7FLI1_27457419_Chip-Seq_LIVER_Mouse2.76510688
8VDR_22108803_ChIP-Seq_LS180_Human2.68001021
9RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.44811224
10ZNF274_21170338_ChIP-Seq_K562_Hela2.44479683
11PCGF2_27294783_Chip-Seq_ESCs_Mouse2.28516387
12GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.27188650
13IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.23209336
14RUNX_20019798_ChIP-Seq_JUKART_Human2.16743384
15IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.14045844
16POU3F2_20337985_ChIP-ChIP_501MEL_Human2.02965338
17IRF8_27001747_Chip-Seq_BMDM_Mouse1.98027383
18STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.92515014
19NFE2_27457419_Chip-Seq_LIVER_Mouse1.90243308
20SALL1_21062744_ChIP-ChIP_HESCs_Human1.88333198
21PCGF2_27294783_Chip-Seq_NPCs_Mouse1.87996808
22ER_23166858_ChIP-Seq_MCF-7_Human1.86844798
23SUZ12_27294783_Chip-Seq_NPCs_Mouse1.85908377
24EZH2_27294783_Chip-Seq_NPCs_Mouse1.85123671
25MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.84209503
26GBX2_23144817_ChIP-Seq_PC3_Human1.80191508
27NOTCH1_21737748_ChIP-Seq_TLL_Human1.75946361
28GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.69351940
29IRF1_19129219_ChIP-ChIP_H3396_Human1.66221707
30POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.65737667
31TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.65737667
32GATA3_26560356_Chip-Seq_TH2_Human1.58914878
33CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.58278273
34TAF15_26573619_Chip-Seq_HEK293_Human1.50524456
35MYB_26560356_Chip-Seq_TH2_Human1.49392481
36SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.49188930
37BCAT_22108803_ChIP-Seq_LS180_Human1.46992113
38SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.42926751
39FUS_26573619_Chip-Seq_HEK293_Human1.39737936
40CRX_20693478_ChIP-Seq_RETINA_Mouse1.38280189
41EGR1_23403033_ChIP-Seq_LIVER_Mouse1.36941539
42GATA3_27048872_Chip-Seq_THYMUS_Human1.36388077
43SPI1_23547873_ChIP-Seq_NB4_Human1.35739801
44FLI1_21867929_ChIP-Seq_TH2_Mouse1.34748789
45FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.34327994
46ZFP57_27257070_Chip-Seq_ESCs_Mouse1.32905821
47PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.30854456
48OCT4_21477851_ChIP-Seq_ESCs_Mouse1.30833516
49STAT3_23295773_ChIP-Seq_U87_Human1.30483862
50P300_19829295_ChIP-Seq_ESCs_Human1.29132894
51SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.26997850
52VDR_24787735_ChIP-Seq_THP-1_Human1.25428950
53AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.25124683
54TCF4_23295773_ChIP-Seq_U87_Human1.22476839
55PRDM14_20953172_ChIP-Seq_ESCs_Human1.21316341
56LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.21263156
57CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.19992067
58IGF1R_20145208_ChIP-Seq_DFB_Human1.19944584
59FOXA1_21572438_ChIP-Seq_LNCaP_Human1.19696871
60EWS_26573619_Chip-Seq_HEK293_Human1.19644918
61MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.18936156
62UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.18220786
63Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.17094704
64CDX2_22108803_ChIP-Seq_LS180_Human1.15898122
65P53_22387025_ChIP-Seq_ESCs_Mouse1.15593033
66IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.14856496
67CBP_20019798_ChIP-Seq_JUKART_Human1.14856496
68SMRT_27268052_Chip-Seq_Bcells_Human1.14792636
69FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.13989706
70NANOG_18555785_Chip-Seq_ESCs_Mouse1.13300916
71MYB_26560356_Chip-Seq_TH1_Human1.13013834
72CDX2_19796622_ChIP-Seq_MESCs_Mouse1.12905091
73BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.11727456
74GATA1_22025678_ChIP-Seq_K562_Human1.11165204
75STAT3_18555785_Chip-Seq_ESCs_Mouse1.09268486
76NANOG_19829295_ChIP-Seq_ESCs_Human1.08999465
77SOX2_19829295_ChIP-Seq_ESCs_Human1.08999465
78E2F1_18555785_Chip-Seq_ESCs_Mouse1.08209542
79EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.07950150
80SCL_19346495_ChIP-Seq_HPC-7_Human1.07890417
81HTT_18923047_ChIP-ChIP_STHdh_Human1.07225586
82TP53_16413492_ChIP-PET_HCT116_Human1.06674611
83SMAD4_21799915_ChIP-Seq_A2780_Human1.06606287
84SPI1_23127762_ChIP-Seq_K562_Human1.06587493
85P300_18555785_Chip-Seq_ESCs_Mouse1.06056989
86TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.05963669
87GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human1.05472926
88EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.05000235
89TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.04009653
90CTCF_18555785_Chip-Seq_ESCs_Mouse1.02220256
91FOXA1_25329375_ChIP-Seq_VCAP_Human1.02050432
92FOXA1_27270436_Chip-Seq_PROSTATE_Human1.02050432
93TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.01112851
94TP53_22573176_ChIP-Seq_HFKS_Human1.00989690
95FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.00629365
96CMYC_18555785_Chip-Seq_ESCs_Mouse0.99824730
97SALL4_22934838_ChIP-ChIP_CD34+_Human0.99306062
98SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.98883508
99EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.98830581
100MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.98167528

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation5.99803919
2MP0003724_increased_susceptibility_to5.14929499
3MP0003195_calcinosis3.47307576
4MP0008877_abnormal_DNA_methylation3.30229759
5MP0003787_abnormal_imprinting3.20910907
6MP0009278_abnormal_bone_marrow2.96417086
7MP0003191_abnormal_cellular_cholesterol2.92496317
8MP0004381_abnormal_hair_follicle2.39117971
9MP0009764_decreased_sensitivity_to2.37462266
10MP0000015_abnormal_ear_pigmentation2.31718966
11MP0001835_abnormal_antigen_presentation2.29637635
12MP0001800_abnormal_humoral_immune2.17502925
13MP0009785_altered_susceptibility_to2.17497628
14MP0000427_abnormal_hair_cycle2.08952438
15MP0005671_abnormal_response_to1.97141536
16MP0000685_abnormal_immune_system1.92065803
17MP0002723_abnormal_immune_serum1.84233849
18MP0005174_abnormal_tail_pigmentation1.79786381
19MP0008260_abnormal_autophagy1.78341631
20MP0005310_abnormal_salivary_gland1.77144058
21MP0002419_abnormal_innate_immunity1.73688171
22MP0002876_abnormal_thyroid_physiology1.73549621
23MP0003172_abnormal_lysosome_physiology1.70324153
24MP0005397_hematopoietic_system_phenotyp1.69805145
25MP0001545_abnormal_hematopoietic_system1.69805145
26MP0002452_abnormal_antigen_presenting1.66187223
27MP0002148_abnormal_hypersensitivity_rea1.66169686
28MP0005025_abnormal_response_to1.65623635
29MP0002653_abnormal_ependyma_morphology1.65582438
30MP0002420_abnormal_adaptive_immunity1.62421483
31MP0001819_abnormal_immune_cell1.62131013
32MP0005075_abnormal_melanosome_morpholog1.60836187
33MP0003436_decreased_susceptibility_to1.56933866
34MP0002132_abnormal_respiratory_system1.54887407
35MP0003221_abnormal_cardiomyocyte_apopto1.54720335
36MP0002277_abnormal_respiratory_mucosa1.54395688
37MP0004484_altered_response_of1.53825467
38MP0005000_abnormal_immune_tolerance1.51446959
39MP0009333_abnormal_splenocyte_physiolog1.39278959
40MP0005387_immune_system_phenotype1.39260487
41MP0001790_abnormal_immune_system1.39260487
42MP0008057_abnormal_DNA_replication1.38969769
43MP0002405_respiratory_system_inflammati1.36043757
44MP0004883_abnormal_blood_vessel1.32672233
45MP0001533_abnormal_skeleton_physiology1.31790348
46MP0002396_abnormal_hematopoietic_system1.30328621
47MP0003646_muscle_fatigue1.29919160
48MP0000716_abnormal_immune_system1.29726649
49MP0003763_abnormal_thymus_physiology1.29063169
50MP0003656_abnormal_erythrocyte_physiolo1.25050410
51MP0002166_altered_tumor_susceptibility1.22814027
52MP0000604_amyloidosis1.19665278
53MP0002398_abnormal_bone_marrow1.19166154
54MP0003329_amyloid_beta_deposits1.17866170
55MP0001845_abnormal_inflammatory_respons1.16845468
56MP0002095_abnormal_skin_pigmentation1.16231851
57MP0006082_CNS_inflammation1.15482371
58MP0000689_abnormal_spleen_morphology1.13288445
59MP0003632_abnormal_nervous_system1.12393805
60MP0001968_abnormal_touch/_nociception1.08432955
61MP0002722_abnormal_immune_system1.06877787
62MP0004885_abnormal_endolymph1.05491001
63MP0004130_abnormal_muscle_cell1.00762985
64MP0001986_abnormal_taste_sensitivity0.99363988
65MP0003690_abnormal_glial_cell0.96777039
66MP0005164_abnormal_response_to0.95772228
67MP0000703_abnormal_thymus_morphology0.95442094
68MP0004142_abnormal_muscle_tone0.93286938
69MP0002429_abnormal_blood_cell0.92757806
70MP0003121_genomic_imprinting0.89572019
71MP0001851_eye_inflammation0.87702170
72MP0004043_abnormal_pH_regulation0.86207170
73MP0003631_nervous_system_phenotype0.85655374
74MP0003866_abnormal_defecation0.84419568
75MP0004742_abnormal_vestibular_system0.83150059
76MP0001501_abnormal_sleep_pattern0.82323643
77MP0002332_abnormal_exercise_endurance0.81025531
78MP0009780_abnormal_chondrocyte_physiolo0.80772268
79MP0006035_abnormal_mitochondrial_morpho0.79771103
80MP0000372_irregular_coat_pigmentation0.78139446
81MP0002693_abnormal_pancreas_physiology0.77992203
82MP0000383_abnormal_hair_follicle0.77372479
83MP0005464_abnormal_platelet_physiology0.77088429
84MP0009840_abnormal_foam_cell0.76192336
85MP0009765_abnormal_xenobiotic_induced0.75286265
86MP0005360_urolithiasis0.74631470
87MP0002006_tumorigenesis0.74230405
88MP0005187_abnormal_penis_morphology0.74019877
89MP0003633_abnormal_nervous_system0.71494166
90MP0001664_abnormal_digestion0.70656313
91MP0003828_pulmonary_edema0.69848561
92MP0005389_reproductive_system_phenotype0.69366502
93MP0006276_abnormal_autonomic_nervous0.69264176
94MP0008469_abnormal_protein_level0.68820478
95MP0005376_homeostasis/metabolism_phenot0.68099317
96MP0005551_abnormal_eye_electrophysiolog0.66526383
97MP0002638_abnormal_pupillary_reflex0.64883812
98MP0002928_abnormal_bile_duct0.63514646
99MP0003880_abnormal_central_pattern0.62515448
100MP0009745_abnormal_behavioral_response0.60040511

Predicted human phenotypes

RankGene SetZ-score
1Orchitis (HP:0100796)4.64338988
2Stomatitis (HP:0010280)4.54880517
3Optic neuritis (HP:0100653)4.51223291
4Retrobulbar optic neuritis (HP:0100654)4.51223291
5Myositis (HP:0100614)4.42451563
6Recurrent bacterial skin infections (HP:0005406)4.05946369
7Elevated erythrocyte sedimentation rate (HP:0003565)3.78473798
8Recurrent abscess formation (HP:0002722)3.73639672
9Concave nail (HP:0001598)3.50222560
10Gastrointestinal infarctions (HP:0005244)3.45757827
11Intestinal atresia (HP:0011100)3.41700135
12Autoimmune hemolytic anemia (HP:0001890)3.41175230
13Parkinsonism with favorable response to dopaminergic medication (HP:0002548)3.35993126
14Abnormality of T cell number (HP:0011839)3.32119533
15T lymphocytopenia (HP:0005403)3.28741779
16Thyroid-stimulating hormone excess (HP:0002925)3.24712733
17Keratoconjunctivitis sicca (HP:0001097)3.17668860
18Keratoconjunctivitis (HP:0001096)3.17558950
19Arterial thrombosis (HP:0004420)3.17144867
20Recurrent gram-negative bacterial infections (HP:0005420)3.15545577
21Volvulus (HP:0002580)3.15155109
22Decreased central vision (HP:0007663)3.11152234
23Recurrent fungal infections (HP:0002841)2.97440760
24Mutism (HP:0002300)2.91468700
25Eczematoid dermatitis (HP:0000976)2.82645401
26Pancreatic cysts (HP:0001737)2.77795871
27Methylmalonic acidemia (HP:0002912)2.74719583
28Large for gestational age (HP:0001520)2.74610751
29Inability to walk (HP:0002540)2.63399368
30Mediastinal lymphadenopathy (HP:0100721)2.62622737
31Hyperglycinemia (HP:0002154)2.61423002
32Encephalitis (HP:0002383)2.60322671
33Hemoptysis (HP:0002105)2.59880461
34Recurrent skin infections (HP:0001581)2.54955306
35Chronic mucocutaneous candidiasis (HP:0002728)2.51847567
36Recurrent cutaneous fungal infections (HP:0011370)2.51847567
37Chest pain (HP:0100749)2.51363754
38Gaze-evoked nystagmus (HP:0000640)2.50986326
39Gangrene (HP:0100758)2.49938486
40Pancreatic islet-cell hyperplasia (HP:0004510)2.47712776
41Peritonitis (HP:0002586)2.46618139
42Tubular atrophy (HP:0000092)2.45468242
43Tented upper lip vermilion (HP:0010804)2.44438214
44Attenuation of retinal blood vessels (HP:0007843)2.43719671
45Abnormal delayed hypersensitivity skin test (HP:0002963)2.42773245
46Abnormality of T cells (HP:0002843)2.41770230
47Pulmonary infiltrates (HP:0002113)2.38438238
48Gingival bleeding (HP:0000225)2.37840982
49Facial diplegia (HP:0001349)2.36687359
50Keratitis (HP:0000491)2.33745383
51Anorexia (HP:0002039)2.33402424
52Broad alveolar ridges (HP:0000187)2.33104673
53Abnormality of midbrain morphology (HP:0002418)2.32326360
54Molar tooth sign on MRI (HP:0002419)2.32326360
55Pulmonary embolism (HP:0002204)2.31500759
56Stomach cancer (HP:0012126)2.28077403
57Postural instability (HP:0002172)2.26204592
58Vasculitis (HP:0002633)2.25045757
59True hermaphroditism (HP:0010459)2.24040046
60Pancreatic fibrosis (HP:0100732)2.15089213
61Disproportionate short-trunk short stature (HP:0003521)2.13255968
62Gingivitis (HP:0000230)2.12555450
63Absent rod-and cone-mediated responses on ERG (HP:0007688)2.09345659
64Hypochromic microcytic anemia (HP:0004840)2.09134427
65IgG deficiency (HP:0004315)2.05848010
66Hip dysplasia (HP:0001385)2.04530761
67Episodic fever (HP:0001954)2.04119764
68Hypoproteinemia (HP:0003075)2.01497201
69Recurrent bronchitis (HP:0002837)1.99578019
70Neoplasm of the tracheobronchial system (HP:0100552)1.99301728
71Methylmalonic aciduria (HP:0012120)1.98449356
72Leukocytosis (HP:0001974)1.98363922
73Meningitis (HP:0001287)1.97907227
74Genetic anticipation (HP:0003743)1.96888793
75Chronic diarrhea (HP:0002028)1.96172228
76Spontaneous abortion (HP:0005268)1.95614295
77Visual hallucinations (HP:0002367)1.93841056
78Progressive inability to walk (HP:0002505)1.91030091
79Abnormality of dental color (HP:0011073)1.90439068
80Chronic obstructive pulmonary disease (HP:0006510)1.89895928
81Obstructive lung disease (HP:0006536)1.89895928
82Ketosis (HP:0001946)1.89590844
83Abnormal rod and cone electroretinograms (HP:0008323)1.89420725
84Pustule (HP:0200039)1.88740176
85Abnormality of the endocardium (HP:0004306)1.87407192
86Embryonal renal neoplasm (HP:0011794)1.86009563
87Nephroblastoma (Wilms tumor) (HP:0002667)1.85817238
88Abnormality of macrophages (HP:0004311)1.82042814
89Thyroiditis (HP:0100646)1.79555764
90Urticaria (HP:0001025)1.79238918
91Cheilitis (HP:0100825)1.79095254
92Abolished electroretinogram (ERG) (HP:0000550)1.78518814
93Abnormality of the ileum (HP:0001549)1.78158346
94Furrowed tongue (HP:0000221)1.76707472
95Abnormality of T cell physiology (HP:0011840)1.76123636
96Nephronophthisis (HP:0000090)1.74767534
97Periodontitis (HP:0000704)1.74740135
98Abnormality of the renal cortex (HP:0011035)1.74721285
99Macular degeneration (HP:0000608)1.74160775
100Alveolar cell carcinoma (HP:0006519)1.73793692

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK4.90017289
2ADRBK24.61997828
3MAP2K33.11785569
4TXK3.03930146
5BLK3.01366728
6RIPK42.30899648
7PINK12.16515803
8IRAK12.04357504
9IRAK42.00486884
10MAP4K11.92577611
11ZAK1.84796689
12MAP3K61.81987569
13DAPK21.70516956
14CAMKK21.69710956
15FES1.66897449
16PTK2B1.56689090
17TAOK31.55229873
18GRK61.52841510
19MAP2K61.48555962
20ACVR1B1.47976095
21JAK31.46639282
22IKBKE1.40346433
23BMPR1B1.38185993
24FGR1.37306948
25MAP3K21.32323736
26NUAK11.31301877
27ADRBK11.30761312
28PIK3CG1.30712573
29PIK3CA1.27579355
30IRAK21.26226957
31ITK1.25891231
32SYK1.23899389
33PLK21.23678693
34CASK1.21163983
35MAP2K41.21097744
36CSK1.19432943
37HCK1.16274627
38GRK51.12337632
39JAK21.11922622
40LYN1.10936805
41TEC1.08219607
42PAK31.06839010
43WNK11.04541188
44STK381.00140917
45BTK0.99592196
46KIT0.97719798
47OXSR10.94346320
48RAF10.93168154
49JAK10.88927505
50CAMKK10.88714041
51FGFR30.87826327
52WNK40.87602472
53TYK20.85308828
54ERBB20.84864058
55MAP3K30.84853110
56MAP3K50.82285863
57LCK0.81630888
58SGK20.80720731
59GRK10.78735201
60DYRK30.77254939
61EPHA30.75434387
62BMPR20.74105333
63PRKCQ0.70734401
64PIM10.70023542
65DYRK1A0.69505259
66RPS6KA50.69197377
67STK40.67294285
68PDK10.67016713
69STK38L0.66373710
70TGFBR10.66368833
71ZAP700.66119048
72PRKCE0.65911265
73YES10.65126956
74TLK10.64989659
75IKBKB0.63461984
76EPHB10.60065914
77CSF1R0.59590440
78WNK30.59007292
79NLK0.58183398
80CLK10.57565549
81ERBB30.53844320
82MATK0.53783714
83FGFR20.50708471
84MAP3K110.48996345
85SGK30.48892998
86TNK20.48523866
87MAPK130.48078667
88ERN10.47750434
89GRK70.47744757
90MAP3K10.43558732
91STK110.43327462
92CAMK40.41875411
93BCR0.41590411
94MARK30.40163185
95CDK190.39929927
96ALK0.39829760
97CHUK0.39435965
98ABL10.38103394
99KSR20.35761981
100CAMK10.35545637

Predicted pathways (KEGG)

RankGene SetZ-score
1Taurine and hypotaurine metabolism_Homo sapiens_hsa004304.22023821
2Butanoate metabolism_Homo sapiens_hsa006502.69893244
3NOD-like receptor signaling pathway_Homo sapiens_hsa046212.45304752
4Leishmaniasis_Homo sapiens_hsa051402.37797268
5Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.10192475
6Type I diabetes mellitus_Homo sapiens_hsa049402.10152881
7Staphylococcus aureus infection_Homo sapiens_hsa051502.03830652
8Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.96961066
9Dorso-ventral axis formation_Homo sapiens_hsa043201.88309230
10Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.86055908
11Allograft rejection_Homo sapiens_hsa053301.85795221
12Graft-versus-host disease_Homo sapiens_hsa053321.80690210
13Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.79727318
14Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.76219986
15Osteoclast differentiation_Homo sapiens_hsa043801.75955492
16Measles_Homo sapiens_hsa051621.75326128
17Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.73189007
18Tuberculosis_Homo sapiens_hsa051521.72050178
19Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.71748021
20Autoimmune thyroid disease_Homo sapiens_hsa053201.70706779
21Jak-STAT signaling pathway_Homo sapiens_hsa046301.69325896
22RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.67316514
23alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.66380440
24T cell receptor signaling pathway_Homo sapiens_hsa046601.60979996
25Legionellosis_Homo sapiens_hsa051341.58254720
26Linoleic acid metabolism_Homo sapiens_hsa005911.56603618
27Toll-like receptor signaling pathway_Homo sapiens_hsa046201.56547860
28ABC transporters_Homo sapiens_hsa020101.51064968
29NF-kappa B signaling pathway_Homo sapiens_hsa040641.43190583
30B cell receptor signaling pathway_Homo sapiens_hsa046621.39576183
31Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.37553500
32Primary immunodeficiency_Homo sapiens_hsa053401.37532488
33Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.26880538
34Nitrogen metabolism_Homo sapiens_hsa009101.26292295
35Hematopoietic cell lineage_Homo sapiens_hsa046401.26270669
36Olfactory transduction_Homo sapiens_hsa047401.20583765
37Intestinal immune network for IgA production_Homo sapiens_hsa046721.14744789
38Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.11603026
39Malaria_Homo sapiens_hsa051441.07795891
40Caffeine metabolism_Homo sapiens_hsa002321.07305041
41Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.07251551
42Arachidonic acid metabolism_Homo sapiens_hsa005901.05112928
43Toxoplasmosis_Homo sapiens_hsa051451.05108720
44Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.04223551
45Regulation of autophagy_Homo sapiens_hsa041401.01316674
46Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.94710272
47TNF signaling pathway_Homo sapiens_hsa046680.94067902
48Non-small cell lung cancer_Homo sapiens_hsa052230.90393931
49Basal transcription factors_Homo sapiens_hsa030220.89286480
50Influenza A_Homo sapiens_hsa051640.88095485
51Chemokine signaling pathway_Homo sapiens_hsa040620.87469435
52FoxO signaling pathway_Homo sapiens_hsa040680.86997640
53Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.86985095
54Ether lipid metabolism_Homo sapiens_hsa005650.85702260
55Fatty acid biosynthesis_Homo sapiens_hsa000610.80007472
56Vitamin digestion and absorption_Homo sapiens_hsa049770.79482087
57Phagosome_Homo sapiens_hsa041450.78439027
58Apoptosis_Homo sapiens_hsa042100.78030463
59Hepatitis C_Homo sapiens_hsa051600.76436592
60Rheumatoid arthritis_Homo sapiens_hsa053230.76160486
61Steroid hormone biosynthesis_Homo sapiens_hsa001400.74295125
62Herpes simplex infection_Homo sapiens_hsa051680.71300400
63Platelet activation_Homo sapiens_hsa046110.68778749
64Taste transduction_Homo sapiens_hsa047420.67987937
65Hepatitis B_Homo sapiens_hsa051610.67404296
66Phototransduction_Homo sapiens_hsa047440.62039865
67Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.61624829
68Prolactin signaling pathway_Homo sapiens_hsa049170.57783375
69Morphine addiction_Homo sapiens_hsa050320.57384365
70Asthma_Homo sapiens_hsa053100.57225907
71Antigen processing and presentation_Homo sapiens_hsa046120.54051385
72Carbohydrate digestion and absorption_Homo sapiens_hsa049730.53795939
73Homologous recombination_Homo sapiens_hsa034400.50462677
74p53 signaling pathway_Homo sapiens_hsa041150.50372125
75Transcriptional misregulation in cancer_Homo sapiens_hsa052020.49328517
76Glycerophospholipid metabolism_Homo sapiens_hsa005640.48048988
77Sphingolipid signaling pathway_Homo sapiens_hsa040710.46836426
78Insulin resistance_Homo sapiens_hsa049310.46558705
79Choline metabolism in cancer_Homo sapiens_hsa052310.45961476
80SNARE interactions in vesicular transport_Homo sapiens_hsa041300.45010784
81Adipocytokine signaling pathway_Homo sapiens_hsa049200.44650444
82Tryptophan metabolism_Homo sapiens_hsa003800.44292644
83Phosphatidylinositol signaling system_Homo sapiens_hsa040700.42406010
84Inositol phosphate metabolism_Homo sapiens_hsa005620.42344775
85MAPK signaling pathway_Homo sapiens_hsa040100.39961329
86Collecting duct acid secretion_Homo sapiens_hsa049660.39804255
87Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.39548783
88Acute myeloid leukemia_Homo sapiens_hsa052210.39503771
89Primary bile acid biosynthesis_Homo sapiens_hsa001200.39475439
90Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.38112882
91Systemic lupus erythematosus_Homo sapiens_hsa053220.37599164
92African trypanosomiasis_Homo sapiens_hsa051430.36325604
93Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.36317129
94VEGF signaling pathway_Homo sapiens_hsa043700.35317534
95Mineral absorption_Homo sapiens_hsa049780.34644139
96Pertussis_Homo sapiens_hsa051330.34156587
97Leukocyte transendothelial migration_Homo sapiens_hsa046700.32655112
98Glycosaminoglycan degradation_Homo sapiens_hsa005310.32374794
99Ras signaling pathway_Homo sapiens_hsa040140.30275706
100Neurotrophin signaling pathway_Homo sapiens_hsa047220.29827896

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »