

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of action potential (GO:0098900) | 9.99732255 |
| 2 | positive regulation of cardiac muscle hypertrophy (GO:0010613) | 8.65862429 |
| 3 | positive regulation of muscle hypertrophy (GO:0014742) | 8.65862429 |
| 4 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO | 8.57047889 |
| 5 | response to pheromone (GO:0019236) | 7.89457867 |
| 6 | endoplasmic reticulum calcium ion homeostasis (GO:0032469) | 7.56340146 |
| 7 | regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 7.43811325 |
| 8 | relaxation of muscle (GO:0090075) | 6.89703946 |
| 9 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880) | 6.65448831 |
| 10 | regulation of heart rate by cardiac conduction (GO:0086091) | 6.53996745 |
| 11 | regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314) | 5.64873351 |
| 12 | regulation of the force of heart contraction (GO:0002026) | 5.56204952 |
| 13 | fatty acid elongation (GO:0030497) | 5.31746252 |
| 14 | regulation of cardiac muscle hypertrophy (GO:0010611) | 5.24054462 |
| 15 | cardiac conduction (GO:0061337) | 5.23396392 |
| 16 | regulation of muscle hypertrophy (GO:0014743) | 5.03277294 |
| 17 | anatomical structure regression (GO:0060033) | 4.81488588 |
| 18 | regulation of histone deacetylation (GO:0031063) | 4.80647493 |
| 19 | protein localization to cilium (GO:0061512) | 4.58788337 |
| 20 | reverse cholesterol transport (GO:0043691) | 4.48572975 |
| 21 | platelet dense granule organization (GO:0060155) | 4.47099600 |
| 22 | keratinocyte development (GO:0003334) | 4.46366569 |
| 23 | regulation of sodium ion transmembrane transporter activity (GO:2000649) | 4.36526301 |
| 24 | regulation of cardiac muscle contraction (GO:0055117) | 4.05085606 |
| 25 | negative regulation of ion transmembrane transporter activity (GO:0032413) | 3.95728420 |
| 26 | kinetochore organization (GO:0051383) | 3.94211507 |
| 27 | DNA strand renaturation (GO:0000733) | 3.93811925 |
| 28 | kinetochore assembly (GO:0051382) | 3.88662261 |
| 29 | DNA integration (GO:0015074) | 3.79103747 |
| 30 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.74677678 |
| 31 | regulation of muscle adaptation (GO:0043502) | 3.61922916 |
| 32 | regulation of sodium ion transmembrane transport (GO:1902305) | 3.60350865 |
| 33 | regulation of membrane depolarization (GO:0003254) | 3.54871823 |
| 34 | multicellular organismal signaling (GO:0035637) | 3.54484227 |
| 35 | neural tube formation (GO:0001841) | 3.51131824 |
| 36 | peptidyl-arginine N-methylation (GO:0035246) | 3.37393952 |
| 37 | peptidyl-arginine methylation (GO:0018216) | 3.37393952 |
| 38 | negative regulation of transporter activity (GO:0032410) | 3.33003905 |
| 39 | hindbrain development (GO:0030902) | 3.30761981 |
| 40 | phospholipid efflux (GO:0033700) | 3.29385559 |
| 41 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 3.25853784 |
| 42 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 3.25853784 |
| 43 | regulation of translation, ncRNA-mediated (GO:0045974) | 3.25853784 |
| 44 | phospholipid homeostasis (GO:0055091) | 3.24291388 |
| 45 | proteasome assembly (GO:0043248) | 3.21514525 |
| 46 | regulation of protein deacetylation (GO:0090311) | 3.21382342 |
| 47 | cellular response to leptin stimulus (GO:0044320) | 3.19035818 |
| 48 | replication fork processing (GO:0031297) | 3.18678703 |
| 49 | regulation of striated muscle contraction (GO:0006942) | 3.17568321 |
| 50 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.14465473 |
| 51 | protein localization to kinetochore (GO:0034501) | 3.13883925 |
| 52 | regulation of cardiac muscle cell contraction (GO:0086004) | 3.13018336 |
| 53 | plasma lipoprotein particle assembly (GO:0034377) | 3.07131814 |
| 54 | regulation of cilium movement (GO:0003352) | 3.07003876 |
| 55 | negative regulation of ion transmembrane transport (GO:0034766) | 3.03015654 |
| 56 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.02977029 |
| 57 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.02977029 |
| 58 | actin-mediated cell contraction (GO:0070252) | 3.01767746 |
| 59 | glial cell proliferation (GO:0014009) | 2.98665549 |
| 60 | coenzyme catabolic process (GO:0009109) | 2.96296667 |
| 61 | L-methionine salvage (GO:0071267) | 2.96001580 |
| 62 | L-methionine biosynthetic process (GO:0071265) | 2.96001580 |
| 63 | amino acid salvage (GO:0043102) | 2.96001580 |
| 64 | cellular response to calcium ion (GO:0071277) | 2.95819821 |
| 65 | response to lipoprotein particle (GO:0055094) | 2.91396902 |
| 66 | tRNA methylation (GO:0030488) | 2.91328198 |
| 67 | regulation of calcium ion transmembrane transporter activity (GO:1901019) | 2.86535406 |
| 68 | regulation of calcium ion transmembrane transport (GO:1903169) | 2.86535406 |
| 69 | L-serine transport (GO:0015825) | 2.85648729 |
| 70 | C-terminal protein lipidation (GO:0006501) | 2.81201106 |
| 71 | lipopolysaccharide biosynthetic process (GO:0009103) | 2.79372923 |
| 72 | regulation of release of sequestered calcium ion into cytosol (GO:0051279) | 2.79221106 |
| 73 | oligodendrocyte development (GO:0014003) | 2.78681318 |
| 74 | negative regulation of transmembrane transport (GO:0034763) | 2.77782459 |
| 75 | ER overload response (GO:0006983) | 2.77729094 |
| 76 | mitochondrial RNA metabolic process (GO:0000959) | 2.72228907 |
| 77 | branch elongation of an epithelium (GO:0060602) | 2.66313849 |
| 78 | artery smooth muscle contraction (GO:0014824) | 2.63213718 |
| 79 | midbrain development (GO:0030901) | 2.58772846 |
| 80 | ventricular system development (GO:0021591) | 2.57978928 |
| 81 | peptidyl-threonine phosphorylation (GO:0018107) | 2.57814131 |
| 82 | S-adenosylmethionine metabolic process (GO:0046500) | 2.54731573 |
| 83 | tricarboxylic acid metabolic process (GO:0072350) | 2.53181223 |
| 84 | dicarboxylic acid catabolic process (GO:0043649) | 2.51977980 |
| 85 | positive regulation of p38MAPK cascade (GO:1900745) | 2.51346625 |
| 86 | cullin deneddylation (GO:0010388) | 2.50477820 |
| 87 | tricarboxylic acid cycle (GO:0006099) | 2.49794495 |
| 88 | histamine secretion (GO:0001821) | 2.48484279 |
| 89 | serine transport (GO:0032329) | 2.47303843 |
| 90 | protein-lipid complex assembly (GO:0065005) | 2.46815349 |
| 91 | protein K11-linked ubiquitination (GO:0070979) | 2.45093987 |
| 92 | response to leptin (GO:0044321) | 2.44236081 |
| 93 | regulation of sulfur metabolic process (GO:0042762) | 2.44109709 |
| 94 | pentose metabolic process (GO:0019321) | 2.43070206 |
| 95 | intraciliary transport (GO:0042073) | 2.42708233 |
| 96 | meiotic chromosome segregation (GO:0045132) | 2.42576038 |
| 97 | regulation of relaxation of muscle (GO:1901077) | 18.3274829 |
| 98 | negative regulation of sodium ion transport (GO:0010766) | 15.1087747 |
| 99 | regulation of cell communication by electrical coupling (GO:0010649) | 14.4579972 |
| 100 | relaxation of cardiac muscle (GO:0055119) | 12.1645329 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 7.89716209 |
| 2 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 5.18037133 |
| 3 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 3.59851914 |
| 4 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.87627760 |
| 5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.81461308 |
| 6 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.76148593 |
| 7 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.48230042 |
| 8 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.32655709 |
| 9 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.27002126 |
| 10 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.25046326 |
| 11 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.96678509 |
| 12 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.95973897 |
| 13 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.94668986 |
| 14 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.91092307 |
| 15 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.85413644 |
| 16 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.85284099 |
| 17 | VDR_22108803_ChIP-Seq_LS180_Human | 1.72239874 |
| 18 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.70153855 |
| 19 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.69967418 |
| 20 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.69506426 |
| 21 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.66864959 |
| 22 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.65603528 |
| 23 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.62884891 |
| 24 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.58821201 |
| 25 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.58774829 |
| 26 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.57482376 |
| 27 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.56620622 |
| 28 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.55834888 |
| 29 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.55778981 |
| 30 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.55070998 |
| 31 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.54186955 |
| 32 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.53296413 |
| 33 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.49596576 |
| 34 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.48620774 |
| 35 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.45441159 |
| 36 | P300_19829295_ChIP-Seq_ESCs_Human | 1.43266730 |
| 37 | TP53_16413492_ChIP-PET_HCT116_Human | 1.42258721 |
| 38 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.39068482 |
| 39 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.38917957 |
| 40 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.38003648 |
| 41 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.30694806 |
| 42 | RXR_22108803_ChIP-Seq_LS180_Human | 1.30678081 |
| 43 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.29213465 |
| 44 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.27908729 |
| 45 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.27488748 |
| 46 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.26788278 |
| 47 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.25972229 |
| 48 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.25642336 |
| 49 | FUS_26573619_Chip-Seq_HEK293_Human | 1.25071031 |
| 50 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.24227635 |
| 51 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.18578250 |
| 52 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.18578250 |
| 53 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.15796122 |
| 54 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.13673579 |
| 55 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.12221089 |
| 56 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.11437561 |
| 57 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.11393155 |
| 58 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.11107088 |
| 59 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.10526975 |
| 60 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.09236412 |
| 61 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.08304270 |
| 62 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.07729229 |
| 63 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.07588863 |
| 64 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.07584749 |
| 65 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.06784523 |
| 66 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.06437092 |
| 67 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 1.06301509 |
| 68 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.05504358 |
| 69 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.05302058 |
| 70 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.03679053 |
| 71 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.03309868 |
| 72 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.02040712 |
| 73 | AR_25329375_ChIP-Seq_VCAP_Human | 1.01805489 |
| 74 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.01204949 |
| 75 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.99751664 |
| 76 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.99418122 |
| 77 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.98865581 |
| 78 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.98360702 |
| 79 | STAT3_23295773_ChIP-Seq_U87_Human | 0.97998707 |
| 80 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.97788973 |
| 81 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.97788973 |
| 82 | KDM2B_26808549_Chip-Seq_REH_Human | 0.97124362 |
| 83 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.96594568 |
| 84 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.96366630 |
| 85 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.96113564 |
| 86 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 0.95721581 |
| 87 | SOX9_26525672_Chip-Seq_HEART_Mouse | 0.95663609 |
| 88 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.95279552 |
| 89 | FOXP3_21729870_ChIP-Seq_TREG_Human | 0.93369135 |
| 90 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.92593274 |
| 91 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.92401039 |
| 92 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.89868681 |
| 93 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.89235522 |
| 94 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.88538827 |
| 95 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.88538827 |
| 96 | VDR_23849224_ChIP-Seq_CD4+_Human | 0.87739121 |
| 97 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.87615057 |
| 98 | EWS_26573619_Chip-Seq_HEK293_Human | 0.86501538 |
| 99 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 0.85010358 |
| 100 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.82078634 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002254_reproductive_system_inflammat | 8.88522127 |
| 2 | MP0003880_abnormal_central_pattern | 5.36337960 |
| 3 | MP0005423_abnormal_somatic_nervous | 4.74400494 |
| 4 | MP0008995_early_reproductive_senescence | 4.13151459 |
| 5 | MP0004484_altered_response_of | 3.56631155 |
| 6 | MP0003136_yellow_coat_color | 3.27762389 |
| 7 | MP0001661_extended_life_span | 3.21788401 |
| 8 | MP0001984_abnormal_olfaction | 2.99104659 |
| 9 | MP0000372_irregular_coat_pigmentation | 2.75637843 |
| 10 | MP0008877_abnormal_DNA_methylation | 2.42763270 |
| 11 | MP0005166_decreased_susceptibility_to | 2.24738918 |
| 12 | MP0000579_abnormal_nail_morphology | 2.18043822 |
| 13 | MP0001485_abnormal_pinna_reflex | 2.10539683 |
| 14 | MP0005075_abnormal_melanosome_morpholog | 1.93190891 |
| 15 | MP0005551_abnormal_eye_electrophysiolog | 1.93001185 |
| 16 | MP0003191_abnormal_cellular_cholesterol | 1.92012065 |
| 17 | MP0003786_premature_aging | 1.81629940 |
| 18 | MP0003122_maternal_imprinting | 1.73779293 |
| 19 | MP0000383_abnormal_hair_follicle | 1.68325571 |
| 20 | MP0002132_abnormal_respiratory_system | 1.57025923 |
| 21 | MP0005275_abnormal_skin_tensile | 1.55553916 |
| 22 | MP0000647_abnormal_sebaceous_gland | 1.53191875 |
| 23 | MP0000604_amyloidosis | 1.51447938 |
| 24 | MP0004133_heterotaxia | 1.44719935 |
| 25 | MP0008260_abnormal_autophagy | 1.44625452 |
| 26 | MP0002163_abnormal_gland_morphology | 1.41734476 |
| 27 | MP0005253_abnormal_eye_physiology | 1.40530979 |
| 28 | MP0003646_muscle_fatigue | 1.37032408 |
| 29 | MP0002736_abnormal_nociception_after | 1.33907018 |
| 30 | MP0004019_abnormal_vitamin_homeostasis | 1.33615483 |
| 31 | MP0005645_abnormal_hypothalamus_physiol | 1.30419190 |
| 32 | MP0000427_abnormal_hair_cycle | 1.30008729 |
| 33 | MP0004043_abnormal_pH_regulation | 1.27518811 |
| 34 | MP0006054_spinal_hemorrhage | 1.24413704 |
| 35 | MP0004215_abnormal_myocardial_fiber | 1.21506064 |
| 36 | MP0001764_abnormal_homeostasis | 1.20648280 |
| 37 | MP0002938_white_spotting | 1.18768702 |
| 38 | MP0003941_abnormal_skin_development | 1.18273506 |
| 39 | MP0008057_abnormal_DNA_replication | 1.15428513 |
| 40 | MP0001666_abnormal_nutrient_absorption | 1.14531679 |
| 41 | MP0002090_abnormal_vision | 1.13733799 |
| 42 | MP0001873_stomach_inflammation | 1.12905183 |
| 43 | MP0003693_abnormal_embryo_hatching | 1.11683817 |
| 44 | MP0004885_abnormal_endolymph | 1.06299096 |
| 45 | MP0005410_abnormal_fertilization | 1.02910187 |
| 46 | MP0001486_abnormal_startle_reflex | 1.01424908 |
| 47 | MP0003186_abnormal_redox_activity | 1.00783708 |
| 48 | MP0002295_abnormal_pulmonary_circulatio | 1.00768357 |
| 49 | MP0001324_abnormal_eye_pigmentation | 1.00260927 |
| 50 | MP0010094_abnormal_chromosome_stability | 0.94980318 |
| 51 | MP0000749_muscle_degeneration | 0.93256569 |
| 52 | MP0001853_heart_inflammation | 0.92338141 |
| 53 | MP0008872_abnormal_physiological_respon | 0.91113327 |
| 54 | MP0001968_abnormal_touch/_nociception | 0.90826124 |
| 55 | MP0001986_abnormal_taste_sensitivity | 0.89191383 |
| 56 | MP0005636_abnormal_mineral_homeostasis | 0.88924058 |
| 57 | MP0003111_abnormal_nucleus_morphology | 0.88726937 |
| 58 | MP0001756_abnormal_urination | 0.83832792 |
| 59 | MP0006072_abnormal_retinal_apoptosis | 0.83247372 |
| 60 | MP0003221_abnormal_cardiomyocyte_apopto | 0.82714963 |
| 61 | MP0003385_abnormal_body_wall | 0.80263935 |
| 62 | MP0010329_abnormal_lipoprotein_level | 0.79366297 |
| 63 | MP0009703_decreased_birth_body | 0.76926513 |
| 64 | MP0001849_ear_inflammation | 0.76592931 |
| 65 | MP0009697_abnormal_copulation | 0.75367907 |
| 66 | MP0004883_abnormal_blood_vessel | 0.75328228 |
| 67 | MP0001502_abnormal_circadian_rhythm | 0.73650269 |
| 68 | MP0004381_abnormal_hair_follicle | 0.71687300 |
| 69 | MP0005391_vision/eye_phenotype | 0.69146915 |
| 70 | MP0003121_genomic_imprinting | 0.69108120 |
| 71 | MP0010678_abnormal_skin_adnexa | 0.68020660 |
| 72 | MP0004145_abnormal_muscle_electrophysio | 0.67223344 |
| 73 | MP0000639_abnormal_adrenal_gland | 0.66479053 |
| 74 | MP0002136_abnormal_kidney_physiology | 0.65471808 |
| 75 | MP0003119_abnormal_digestive_system | 0.65443718 |
| 76 | MP0002734_abnormal_mechanical_nocicepti | 0.65378485 |
| 77 | MP0003718_maternal_effect | 0.65298448 |
| 78 | MP0005365_abnormal_bile_salt | 0.65011791 |
| 79 | MP0005195_abnormal_posterior_eye | 0.64482870 |
| 80 | MP0008058_abnormal_DNA_repair | 0.64082441 |
| 81 | MP0005379_endocrine/exocrine_gland_phen | 0.63902171 |
| 82 | MP0005197_abnormal_uvea_morphology | 0.61904350 |
| 83 | MP0005310_abnormal_salivary_gland | 0.61450081 |
| 84 | MP0005330_cardiomyopathy | 0.58522532 |
| 85 | MP0002138_abnormal_hepatobiliary_system | 0.57508078 |
| 86 | MP0006292_abnormal_olfactory_placode | 0.56415147 |
| 87 | MP0003937_abnormal_limbs/digits/tail_de | 0.56186674 |
| 88 | MP0000049_abnormal_middle_ear | 0.54094706 |
| 89 | MP0003077_abnormal_cell_cycle | 0.53388556 |
| 90 | MP0005332_abnormal_amino_acid | 0.53050118 |
| 91 | MP0004957_abnormal_blastocyst_morpholog | 0.51604239 |
| 92 | MP0001915_intracranial_hemorrhage | 0.49633707 |
| 93 | MP0000751_myopathy | 0.46726094 |
| 94 | MP0001727_abnormal_embryo_implantation | 0.46636924 |
| 95 | MP0001851_eye_inflammation | 0.45585247 |
| 96 | MP0002229_neurodegeneration | 0.44977851 |
| 97 | MP0003950_abnormal_plasma_membrane | 0.44013328 |
| 98 | MP0003806_abnormal_nucleotide_metabolis | 0.43774032 |
| 99 | MP0002653_abnormal_ependyma_morphology | 0.41577101 |
| 100 | MP0005084_abnormal_gallbladder_morpholo | 0.41159936 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Hypoalphalipoproteinemia (HP:0003233) | 5.65476210 |
| 2 | Congenital, generalized hypertrichosis (HP:0004540) | 4.43201162 |
| 3 | Facial diplegia (HP:0001349) | 4.38940724 |
| 4 | Amelogenesis imperfecta (HP:0000705) | 4.22039704 |
| 5 | Pili torti (HP:0003777) | 4.17490077 |
| 6 | Acute lymphatic leukemia (HP:0006721) | 4.12645653 |
| 7 | Cerebral hypomyelination (HP:0006808) | 4.09136277 |
| 8 | Follicular hyperkeratosis (HP:0007502) | 4.08749524 |
| 9 | High pitched voice (HP:0001620) | 3.95937982 |
| 10 | Action tremor (HP:0002345) | 3.93340464 |
| 11 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 3.69072153 |
| 12 | Short tibia (HP:0005736) | 3.40433965 |
| 13 | CNS hypomyelination (HP:0003429) | 3.30923237 |
| 14 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.25519401 |
| 15 | Abnormality of alanine metabolism (HP:0010916) | 3.25519401 |
| 16 | Hyperalaninemia (HP:0003348) | 3.25519401 |
| 17 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 3.17589492 |
| 18 | Hypolipoproteinemia (HP:0010981) | 3.15467476 |
| 19 | Hyperglycinemia (HP:0002154) | 3.13260112 |
| 20 | Nephronophthisis (HP:0000090) | 3.03198165 |
| 21 | CNS demyelination (HP:0007305) | 2.91806339 |
| 22 | Methylmalonic acidemia (HP:0002912) | 2.85367191 |
| 23 | Hepatocellular necrosis (HP:0001404) | 2.81916202 |
| 24 | Delusions (HP:0000746) | 2.81462549 |
| 25 | Abnormal hair laboratory examination (HP:0003328) | 2.77006276 |
| 26 | Brittle hair (HP:0002299) | 2.76415389 |
| 27 | Methylmalonic aciduria (HP:0012120) | 2.76379427 |
| 28 | Occipital encephalocele (HP:0002085) | 2.66259894 |
| 29 | Hepatic necrosis (HP:0002605) | 2.60302830 |
| 30 | Cerebellar dysplasia (HP:0007033) | 2.50120348 |
| 31 | Concave nail (HP:0001598) | 2.49783639 |
| 32 | Abnormality of the ischium (HP:0003174) | 2.47305795 |
| 33 | Sparse eyelashes (HP:0000653) | 2.46953615 |
| 34 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 2.44795402 |
| 35 | Absent epiphyses (HP:0010577) | 2.44795402 |
| 36 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.35086031 |
| 37 | Double outlet right ventricle (HP:0001719) | 2.31629559 |
| 38 | Congenital malformation of the right heart (HP:0011723) | 2.31629559 |
| 39 | Duplicated collecting system (HP:0000081) | 2.31569845 |
| 40 | Abnormality of the level of lipoprotein cholesterol (HP:0010979) | 2.31155798 |
| 41 | Molar tooth sign on MRI (HP:0002419) | 2.28299420 |
| 42 | Abnormality of midbrain morphology (HP:0002418) | 2.28299420 |
| 43 | Large for gestational age (HP:0001520) | 2.27174403 |
| 44 | Disproportionate short-trunk short stature (HP:0003521) | 2.26502378 |
| 45 | Severe muscular hypotonia (HP:0006829) | 2.25108477 |
| 46 | Ectropion (HP:0000656) | 2.24969558 |
| 47 | Type I transferrin isoform profile (HP:0003642) | 2.24933363 |
| 48 | Postaxial foot polydactyly (HP:0001830) | 2.24804304 |
| 49 | Abnormality of the renal medulla (HP:0100957) | 2.23729839 |
| 50 | Hepatoblastoma (HP:0002884) | 2.22705849 |
| 51 | Premature ovarian failure (HP:0008209) | 2.22700500 |
| 52 | Fragile skin (HP:0001030) | 2.22130669 |
| 53 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.21619141 |
| 54 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.21619141 |
| 55 | Impaired pain sensation (HP:0007328) | 2.19366506 |
| 56 | Abnormality of pain sensation (HP:0010832) | 2.19366506 |
| 57 | Disinhibition (HP:0000734) | 2.18007488 |
| 58 | Abnormality of the renal collecting system (HP:0004742) | 2.15743226 |
| 59 | Microretrognathia (HP:0000308) | 2.14036434 |
| 60 | Emotional lability (HP:0000712) | 2.13832766 |
| 61 | True hermaphroditism (HP:0010459) | 2.13545638 |
| 62 | Pancreatic fibrosis (HP:0100732) | 2.12559041 |
| 63 | Tubulointerstitial nephritis (HP:0001970) | 2.11984702 |
| 64 | Pancreatic cysts (HP:0001737) | 2.11074372 |
| 65 | Abnormality of serum amino acid levels (HP:0003112) | 2.09346377 |
| 66 | Abnormal protein glycosylation (HP:0012346) | 2.04576359 |
| 67 | Abnormal glycosylation (HP:0012345) | 2.04576359 |
| 68 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.04576359 |
| 69 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.04576359 |
| 70 | Woolly hair (HP:0002224) | 2.00547787 |
| 71 | Ulnar claw (HP:0001178) | 1.93383918 |
| 72 | Acute encephalopathy (HP:0006846) | 1.92081094 |
| 73 | Lactic acidosis (HP:0003128) | 1.91103878 |
| 74 | Neutropenia (HP:0001875) | 1.90826640 |
| 75 | Secondary amenorrhea (HP:0000869) | 1.88201511 |
| 76 | Myokymia (HP:0002411) | 1.86605029 |
| 77 | Lethargy (HP:0001254) | 1.84391227 |
| 78 | Absent radius (HP:0003974) | 1.83261417 |
| 79 | Anal stenosis (HP:0002025) | 1.82971350 |
| 80 | Optic nerve hypoplasia (HP:0000609) | 1.82722423 |
| 81 | Abnormality of the lower motor neuron (HP:0002366) | 1.82014054 |
| 82 | Progressive inability to walk (HP:0002505) | 1.79128000 |
| 83 | Small hand (HP:0200055) | 1.78780433 |
| 84 | Intestinal atresia (HP:0011100) | 1.75145458 |
| 85 | Mitochondrial inheritance (HP:0001427) | 1.74768538 |
| 86 | Stage 5 chronic kidney disease (HP:0003774) | 1.74069573 |
| 87 | Increased CSF lactate (HP:0002490) | 1.73292145 |
| 88 | Areflexia of lower limbs (HP:0002522) | 1.72723309 |
| 89 | Aplasia involving forearm bones (HP:0009822) | 1.71937171 |
| 90 | Absent forearm bone (HP:0003953) | 1.71937171 |
| 91 | Postaxial hand polydactyly (HP:0001162) | 1.70679890 |
| 92 | Median cleft lip (HP:0000161) | 1.69371780 |
| 93 | Central scotoma (HP:0000603) | 1.67805536 |
| 94 | Preaxial hand polydactyly (HP:0001177) | 1.67331568 |
| 95 | Hypoplastic female external genitalia (HP:0012815) | 1.66833617 |
| 96 | Spastic tetraparesis (HP:0001285) | 1.66491672 |
| 97 | Absent eyebrow (HP:0002223) | 1.65524638 |
| 98 | Medial flaring of the eyebrow (HP:0010747) | 1.63368743 |
| 99 | Abnormality of macular pigmentation (HP:0008002) | 1.63113211 |
| 100 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.62145139 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TRIM28 | 5.89290603 |
| 2 | SIK3 | 5.34535055 |
| 3 | MAP4K2 | 4.00931559 |
| 4 | TNIK | 3.03186834 |
| 5 | PINK1 | 2.61746359 |
| 6 | BCR | 2.51287627 |
| 7 | NEK6 | 2.47367495 |
| 8 | STK16 | 2.18146000 |
| 9 | KSR1 | 2.09105542 |
| 10 | CAMK2D | 2.08378302 |
| 11 | PDK2 | 10.0601138 |
| 12 | RPS6KB1 | 1.90903308 |
| 13 | GRK1 | 1.87798025 |
| 14 | FRK | 1.76797961 |
| 15 | MST1R | 1.76189463 |
| 16 | BCKDK | 1.58741849 |
| 17 | WEE1 | 1.54853626 |
| 18 | FES | 1.38185012 |
| 19 | ZAK | 1.30465247 |
| 20 | MINK1 | 1.29183107 |
| 21 | NEK1 | 1.21502208 |
| 22 | NEK9 | 1.13483881 |
| 23 | NLK | 1.13320198 |
| 24 | MET | 1.13016660 |
| 25 | NTRK2 | 0.95435201 |
| 26 | SRPK1 | 0.94006721 |
| 27 | STK39 | 0.92806921 |
| 28 | NEK2 | 0.91504367 |
| 29 | BMPR1B | 0.90814407 |
| 30 | BUB1 | 0.90544969 |
| 31 | PTK2B | 0.79599864 |
| 32 | MAPK7 | 0.78505270 |
| 33 | TTK | 0.75619232 |
| 34 | TRPM7 | 0.74248964 |
| 35 | WNK4 | 0.72669882 |
| 36 | PBK | 0.70298367 |
| 37 | PAK3 | 0.63673306 |
| 38 | STK3 | 0.59111193 |
| 39 | MUSK | 0.53134782 |
| 40 | CDK3 | 0.52841664 |
| 41 | VRK2 | 0.52491028 |
| 42 | BRSK1 | 0.51953572 |
| 43 | OBSCN | 0.51426408 |
| 44 | CDK9 | 0.46575275 |
| 45 | PRKCG | 0.45331836 |
| 46 | BRSK2 | 0.44877131 |
| 47 | FGR | 0.44701746 |
| 48 | MAPK12 | 0.43491785 |
| 49 | STK4 | 0.42582385 |
| 50 | KSR2 | 0.41760209 |
| 51 | OXSR1 | 0.41734184 |
| 52 | TIE1 | 0.40054405 |
| 53 | ATR | 0.38468629 |
| 54 | PLK1 | 0.37948030 |
| 55 | MAP3K2 | 0.36015543 |
| 56 | ERBB4 | 0.35325055 |
| 57 | ADRBK2 | 0.33769996 |
| 58 | MAPK9 | 0.33151910 |
| 59 | CDK7 | 0.33047844 |
| 60 | CCNB1 | 0.30988379 |
| 61 | PRKCB | 0.30945630 |
| 62 | ICK | 0.29858929 |
| 63 | EIF2AK2 | 0.29593384 |
| 64 | PLK3 | 0.29221856 |
| 65 | PRKCE | 0.28339712 |
| 66 | CSF1R | 0.28241826 |
| 67 | CDK8 | 0.25733087 |
| 68 | PDK1 | 0.25633527 |
| 69 | WNK3 | 0.25064004 |
| 70 | MELK | 0.23094109 |
| 71 | PDPK1 | 0.21545578 |
| 72 | STK38 | 0.21344368 |
| 73 | LMTK2 | 0.19182972 |
| 74 | MAP3K14 | 0.18889857 |
| 75 | MST4 | 0.18620249 |
| 76 | PIK3CA | 0.17633793 |
| 77 | PRKACG | 0.17283489 |
| 78 | BRD4 | 0.17262758 |
| 79 | CSNK2A1 | 0.16894838 |
| 80 | PRKACA | 0.15576743 |
| 81 | CHEK1 | 0.13079523 |
| 82 | CAMK2A | 0.12957026 |
| 83 | CDK2 | 0.12594401 |
| 84 | PLK4 | 0.12383610 |
| 85 | MARK1 | 0.11361830 |
| 86 | INSR | 0.10898339 |
| 87 | EGFR | 0.09433114 |
| 88 | MAP2K2 | 0.07975128 |
| 89 | MAP3K8 | 0.07975093 |
| 90 | MAP2K6 | 0.07942762 |
| 91 | TGFBR1 | 0.07308188 |
| 92 | CDK18 | 0.06953908 |
| 93 | GSK3B | 0.06911207 |
| 94 | AKT3 | 0.06351060 |
| 95 | MAP4K1 | 0.05014287 |
| 96 | CDK19 | 0.04827556 |
| 97 | CSNK2A2 | 0.04701324 |
| 98 | PKN1 | 0.04624395 |
| 99 | MAPK10 | 0.03837887 |
| 100 | MTOR | 0.03023939 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 3.66017167 |
| 2 | Fatty acid elongation_Homo sapiens_hsa00062 | 3.28313577 |
| 3 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 3.13145107 |
| 4 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.62901396 |
| 5 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 2.59720243 |
| 6 | Oocyte meiosis_Homo sapiens_hsa04114 | 2.55719229 |
| 7 | Olfactory transduction_Homo sapiens_hsa04740 | 2.44836676 |
| 8 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 2.31487147 |
| 9 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.03414784 |
| 10 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 2.02623561 |
| 11 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.97012117 |
| 12 | Insulin secretion_Homo sapiens_hsa04911 | 1.86358402 |
| 13 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 1.82159717 |
| 14 | Glioma_Homo sapiens_hsa05214 | 1.81920532 |
| 15 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.80699878 |
| 16 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.79043972 |
| 17 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.73705855 |
| 18 | Basal transcription factors_Homo sapiens_hsa03022 | 1.70358148 |
| 19 | Proteasome_Homo sapiens_hsa03050 | 1.69049748 |
| 20 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.68418252 |
| 21 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.66780990 |
| 22 | Renin-angiotensin system_Homo sapiens_hsa04614 | 1.52581257 |
| 23 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.52056113 |
| 24 | RNA polymerase_Homo sapiens_hsa03020 | 1.52005006 |
| 25 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.50498161 |
| 26 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.46882825 |
| 27 | Protein export_Homo sapiens_hsa03060 | 1.46477315 |
| 28 | Circadian entrainment_Homo sapiens_hsa04713 | 1.43915448 |
| 29 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.41119013 |
| 30 | Homologous recombination_Homo sapiens_hsa03440 | 1.37223926 |
| 31 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.36141829 |
| 32 | Long-term potentiation_Homo sapiens_hsa04720 | 1.33470017 |
| 33 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.33019982 |
| 34 | Melanogenesis_Homo sapiens_hsa04916 | 1.32788721 |
| 35 | Mismatch repair_Homo sapiens_hsa03430 | 1.26504177 |
| 36 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.24273063 |
| 37 | ABC transporters_Homo sapiens_hsa02010 | 1.16612123 |
| 38 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 1.16526250 |
| 39 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.14800497 |
| 40 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.10454605 |
| 41 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.09856647 |
| 42 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.08956140 |
| 43 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.07284117 |
| 44 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.07236809 |
| 45 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.05377003 |
| 46 | Peroxisome_Homo sapiens_hsa04146 | 1.00269803 |
| 47 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.94279745 |
| 48 | Parkinsons disease_Homo sapiens_hsa05012 | 0.94009713 |
| 49 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.93273075 |
| 50 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.93193265 |
| 51 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.93009206 |
| 52 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.88126908 |
| 53 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.87820480 |
| 54 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.86803202 |
| 55 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.82661421 |
| 56 | Retinol metabolism_Homo sapiens_hsa00830 | 0.82040676 |
| 57 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.81831258 |
| 58 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.81828264 |
| 59 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.81640479 |
| 60 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.80100670 |
| 61 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.80075934 |
| 62 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.79590621 |
| 63 | Lysine degradation_Homo sapiens_hsa00310 | 0.78845676 |
| 64 | Carbon metabolism_Homo sapiens_hsa01200 | 0.76321161 |
| 65 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.76002437 |
| 66 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.75878402 |
| 67 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.75228911 |
| 68 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.71492541 |
| 69 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.71356728 |
| 70 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.70860154 |
| 71 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.70801783 |
| 72 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.70665269 |
| 73 | Phototransduction_Homo sapiens_hsa04744 | 0.69044975 |
| 74 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.68389468 |
| 75 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.68170283 |
| 76 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.65856698 |
| 77 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.64548393 |
| 78 | Cell cycle_Homo sapiens_hsa04110 | 0.61473961 |
| 79 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.59743744 |
| 80 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.59304313 |
| 81 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.58908985 |
| 82 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.58809343 |
| 83 | RNA degradation_Homo sapiens_hsa03018 | 0.58762909 |
| 84 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.56048944 |
| 85 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.55331922 |
| 86 | Mineral absorption_Homo sapiens_hsa04978 | 0.55151116 |
| 87 | Purine metabolism_Homo sapiens_hsa00230 | 0.54417140 |
| 88 | Huntingtons disease_Homo sapiens_hsa05016 | 0.54111083 |
| 89 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.53228431 |
| 90 | Spliceosome_Homo sapiens_hsa03040 | 0.52175738 |
| 91 | RNA transport_Homo sapiens_hsa03013 | 0.49483709 |
| 92 | Metabolic pathways_Homo sapiens_hsa01100 | 0.45767921 |
| 93 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.44164599 |
| 94 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.43824365 |
| 95 | Alzheimers disease_Homo sapiens_hsa05010 | 0.42683184 |
| 96 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.41457592 |
| 97 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.39768393 |
| 98 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.39154176 |
| 99 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.37421572 |
| 100 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.36892734 |

