

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | lipopolysaccharide biosynthetic process (GO:0009103) | 7.43251974 |
| 2 | regulation of chemokine biosynthetic process (GO:0045073) | 7.28494590 |
| 3 | cellular extravasation (GO:0045123) | 6.82631061 |
| 4 | cellular response to exogenous dsRNA (GO:0071360) | 6.66020435 |
| 5 | positive regulation of chemokine biosynthetic process (GO:0045080) | 6.34340818 |
| 6 | lipopolysaccharide metabolic process (GO:0008653) | 6.33536858 |
| 7 | rRNA methylation (GO:0031167) | 5.60400084 |
| 8 | * detection of chemical stimulus involved in sensory perception of smell (GO:0050911) | 5.58720327 |
| 9 | ether lipid metabolic process (GO:0046485) | 5.36277387 |
| 10 | microglial cell activation (GO:0001774) | 5.31922270 |
| 11 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 5.23100353 |
| 12 | motile cilium assembly (GO:0044458) | 5.12408700 |
| 13 | reciprocal DNA recombination (GO:0035825) | 5.09252543 |
| 14 | reciprocal meiotic recombination (GO:0007131) | 5.09252543 |
| 15 | rRNA modification (GO:0000154) | 5.03665026 |
| 16 | synaptonemal complex assembly (GO:0007130) | 4.82722211 |
| 17 | centriole assembly (GO:0098534) | 4.72794425 |
| 18 | * sensory perception of smell (GO:0007608) | 4.71005903 |
| 19 | pyrimidine nucleotide catabolic process (GO:0006244) | 4.61877943 |
| 20 | killing of cells in other organism involved in symbiotic interaction (GO:0051883) | 4.55367198 |
| 21 | disruption of cells of other organism involved in symbiotic interaction (GO:0051818) | 4.55367198 |
| 22 | replication fork processing (GO:0031297) | 4.53295452 |
| 23 | pyrimidine dimer repair (GO:0006290) | 4.34364502 |
| 24 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 4.30022862 |
| 25 | protoporphyrinogen IX biosynthetic process (GO:0006782) | 4.23379610 |
| 26 | synaptonemal complex organization (GO:0070193) | 4.20428077 |
| 27 | resolution of meiotic recombination intermediates (GO:0000712) | 4.11650885 |
| 28 | glycerol ether metabolic process (GO:0006662) | 3.94777257 |
| 29 | negative regulation of chemokine production (GO:0032682) | 3.87091882 |
| 30 | chromosome organization involved in meiosis (GO:0070192) | 3.86141994 |
| 31 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 3.83633108 |
| 32 | cellular response to interferon-beta (GO:0035458) | 3.82932235 |
| 33 | * detection of chemical stimulus involved in sensory perception (GO:0050907) | 3.78887580 |
| 34 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 3.78080817 |
| 35 | regulation of MHC class II biosynthetic process (GO:0045346) | 3.73747216 |
| 36 | protoporphyrinogen IX metabolic process (GO:0046501) | 3.72669845 |
| 37 | neutrophil mediated immunity (GO:0002446) | 3.65520388 |
| 38 | ether metabolic process (GO:0018904) | 3.64433043 |
| 39 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.58028140 |
| 40 | telomere maintenance via telomerase (GO:0007004) | 3.47593678 |
| 41 | regulation of centriole replication (GO:0046599) | 3.43526276 |
| 42 | DNA topological change (GO:0006265) | 3.37751795 |
| 43 | cellular response to dsRNA (GO:0071359) | 3.34391615 |
| 44 | negative regulation of protein acetylation (GO:1901984) | 3.30362350 |
| 45 | alanine transport (GO:0032328) | 3.29281909 |
| 46 | proteasome assembly (GO:0043248) | 3.28411525 |
| 47 | mitotic recombination (GO:0006312) | 3.25861215 |
| 48 | centriole replication (GO:0007099) | 3.21846276 |
| 49 | mitochondrial DNA replication (GO:0006264) | 3.16352347 |
| 50 | aggressive behavior (GO:0002118) | 3.12795778 |
| 51 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.05033511 |
| 52 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.02320982 |
| 53 | telomere maintenance (GO:0000723) | 3.01918880 |
| 54 | negative regulation of interleukin-8 production (GO:0032717) | 3.01536701 |
| 55 | pseudouridine synthesis (GO:0001522) | 3.01320622 |
| 56 | response to interferon-beta (GO:0035456) | 2.99778880 |
| 57 | telomere organization (GO:0032200) | 2.99461521 |
| 58 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.98012370 |
| 59 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.98012370 |
| 60 | histone H3-K9 methylation (GO:0051567) | 2.97166338 |
| 61 | intra-S DNA damage checkpoint (GO:0031573) | 2.94626165 |
| 62 | DNA synthesis involved in DNA repair (GO:0000731) | 2.93802140 |
| 63 | purine nucleobase biosynthetic process (GO:0009113) | 2.91905225 |
| 64 | double-strand break repair via homologous recombination (GO:0000724) | 2.89616895 |
| 65 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.88478611 |
| 66 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.88478611 |
| 67 | isotype switching (GO:0045190) | 2.88478611 |
| 68 | deoxyribonucleotide catabolic process (GO:0009264) | 2.88229467 |
| 69 | telomere maintenance via telomere lengthening (GO:0010833) | 2.86354381 |
| 70 | telomere maintenance via recombination (GO:0000722) | 2.84968370 |
| 71 | termination of RNA polymerase I transcription (GO:0006363) | 2.84523144 |
| 72 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.82988610 |
| 73 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.82936360 |
| 74 | ATP synthesis coupled proton transport (GO:0015986) | 2.82936360 |
| 75 | recombinational repair (GO:0000725) | 2.81382322 |
| 76 | non-recombinational repair (GO:0000726) | 2.80530118 |
| 77 | double-strand break repair via nonhomologous end joining (GO:0006303) | 2.80530118 |
| 78 | myeloid leukocyte mediated immunity (GO:0002444) | 2.79825996 |
| 79 | regulation of prostaglandin secretion (GO:0032306) | 2.78701579 |
| 80 | L-serine transport (GO:0015825) | 2.78550207 |
| 81 | oxidative phosphorylation (GO:0006119) | 2.78532174 |
| 82 | deoxyribose phosphate catabolic process (GO:0046386) | 2.78414400 |
| 83 | RNA-dependent DNA replication (GO:0006278) | 2.76865276 |
| 84 | regulation of memory T cell differentiation (GO:0043380) | 2.75609740 |
| 85 | positive regulation of mitochondrial fission (GO:0090141) | 2.72631909 |
| 86 | folic acid metabolic process (GO:0046655) | 2.70439747 |
| 87 | DNA replication checkpoint (GO:0000076) | 2.69363970 |
| 88 | protein K6-linked ubiquitination (GO:0085020) | 2.66477433 |
| 89 | DNA strand elongation (GO:0022616) | 2.64559817 |
| 90 | positive regulation of prostaglandin secretion (GO:0032308) | 2.62898997 |
| 91 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.62811469 |
| 92 | DNA recombination (GO:0006310) | 2.61400235 |
| 93 | somatic diversification of immunoglobulins (GO:0016445) | 2.59823944 |
| 94 | erythrocyte development (GO:0048821) | 2.59592957 |
| 95 | membrane protein intracellular domain proteolysis (GO:0031293) | 2.59311973 |
| 96 | nuclear pore complex assembly (GO:0051292) | 2.56552392 |
| 97 | negative regulation of telomere maintenance (GO:0032205) | 2.56186974 |
| 98 | striated muscle atrophy (GO:0014891) | 2.56081701 |
| 99 | response to UV-C (GO:0010225) | 2.54988630 |
| 100 | DNA replication initiation (GO:0006270) | 2.53166941 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 8.48205420 |
| 2 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.97892910 |
| 3 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.75210951 |
| 4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.70860964 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.25277327 |
| 6 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.25236323 |
| 7 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.09411709 |
| 8 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.74314706 |
| 9 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.68410218 |
| 10 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.57172338 |
| 11 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.48148402 |
| 12 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 2.39887962 |
| 13 | VDR_22108803_ChIP-Seq_LS180_Human | 2.39217745 |
| 14 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 2.38066493 |
| 15 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.37185587 |
| 16 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.35545574 |
| 17 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.25438721 |
| 18 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 2.22837504 |
| 19 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.16097137 |
| 20 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 2.11768916 |
| 21 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.09500598 |
| 22 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.08011733 |
| 23 | AR_21572438_ChIP-Seq_LNCaP_Human | 2.07129461 |
| 24 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.05123725 |
| 25 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.03310706 |
| 26 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.01464412 |
| 27 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.00116308 |
| 28 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.93097108 |
| 29 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.92192669 |
| 30 | EWS_26573619_Chip-Seq_HEK293_Human | 1.84332480 |
| 31 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.83790558 |
| 32 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.81611094 |
| 33 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.80849491 |
| 34 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.77882326 |
| 35 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.74662461 |
| 36 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.74119737 |
| 37 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.72327979 |
| 38 | GATA1_22025678_ChIP-Seq_K562_Human | 1.65852926 |
| 39 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.62447276 |
| 40 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.59360323 |
| 41 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.57912064 |
| 42 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.55560884 |
| 43 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.53377386 |
| 44 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.50760210 |
| 45 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.45398338 |
| 46 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.44348420 |
| 47 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.40459625 |
| 48 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.36205118 |
| 49 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.34247790 |
| 50 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.30822809 |
| 51 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.30432174 |
| 52 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.30307439 |
| 53 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.30001559 |
| 54 | FUS_26573619_Chip-Seq_HEK293_Human | 1.27338899 |
| 55 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.25638682 |
| 56 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.24147855 |
| 57 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.23761610 |
| 58 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.20568930 |
| 59 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.17739831 |
| 60 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.16424850 |
| 61 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.14072046 |
| 62 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.08364070 |
| 63 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.08233218 |
| 64 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.07942674 |
| 65 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.06000869 |
| 66 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.05734531 |
| 67 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.03661126 |
| 68 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.02196131 |
| 69 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.00845280 |
| 70 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.99497753 |
| 71 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.97377266 |
| 72 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 0.96754090 |
| 73 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.95932284 |
| 74 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.94955046 |
| 75 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.94375402 |
| 76 | AR_20517297_ChIP-Seq_VCAP_Human | 0.94283005 |
| 77 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.92702728 |
| 78 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.92105791 |
| 79 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.91020948 |
| 80 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.89372114 |
| 81 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.89271288 |
| 82 | NCOR_22424771_ChIP-Seq_293T_Human | 0.88640164 |
| 83 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.88607614 |
| 84 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.86035379 |
| 85 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.85757361 |
| 86 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.85757361 |
| 87 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 0.85348079 |
| 88 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.85137747 |
| 89 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.84727618 |
| 90 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.84727618 |
| 91 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.84586689 |
| 92 | AR_21909140_ChIP-Seq_LNCAP_Human | 0.83103734 |
| 93 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.82373474 |
| 94 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.81163772 |
| 95 | STAT3_23295773_ChIP-Seq_U87_Human | 0.80450391 |
| 96 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.79693132 |
| 97 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.78111650 |
| 98 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.77830766 |
| 99 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.77528161 |
| 100 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.76949966 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0004147_increased_porphyrin_level | 5.23392506 |
| 2 | MP0008877_abnormal_DNA_methylation | 4.58039407 |
| 3 | MP0010094_abnormal_chromosome_stability | 4.02261656 |
| 4 | MP0008995_early_reproductive_senescence | 3.80260495 |
| 5 | MP0008058_abnormal_DNA_repair | 3.42635720 |
| 6 | MP0003123_paternal_imprinting | 3.40918437 |
| 7 | MP0003786_premature_aging | 3.06522830 |
| 8 | MP0002396_abnormal_hematopoietic_system | 2.69211154 |
| 9 | MP0009697_abnormal_copulation | 2.64571583 |
| 10 | MP0001986_abnormal_taste_sensitivity | 2.62751782 |
| 11 | MP0006035_abnormal_mitochondrial_morpho | 2.55257915 |
| 12 | MP0008057_abnormal_DNA_replication | 2.49109782 |
| 13 | MP0003195_calcinosis | 2.33293026 |
| 14 | MP0006036_abnormal_mitochondrial_physio | 2.26156540 |
| 15 | MP0001545_abnormal_hematopoietic_system | 2.23554987 |
| 16 | MP0005397_hematopoietic_system_phenotyp | 2.23554987 |
| 17 | MP0005083_abnormal_biliary_tract | 2.20489893 |
| 18 | MP0003111_abnormal_nucleus_morphology | 2.18332386 |
| 19 | MP0000427_abnormal_hair_cycle | 1.85639314 |
| 20 | MP0005167_abnormal_blood-brain_barrier | 1.82016237 |
| 21 | MP0001502_abnormal_circadian_rhythm | 1.81726167 |
| 22 | MP0003718_maternal_effect | 1.80962143 |
| 23 | MP0003121_genomic_imprinting | 1.76490619 |
| 24 | MP0006292_abnormal_olfactory_placode | 1.74326390 |
| 25 | MP0008775_abnormal_heart_ventricle | 1.72810409 |
| 26 | MP0003693_abnormal_embryo_hatching | 1.68021953 |
| 27 | MP0001727_abnormal_embryo_implantation | 1.57674266 |
| 28 | MP0008872_abnormal_physiological_respon | 1.53372765 |
| 29 | MP0003656_abnormal_erythrocyte_physiolo | 1.51701799 |
| 30 | MP0002160_abnormal_reproductive_system | 1.51002801 |
| 31 | MP0003122_maternal_imprinting | 1.50481231 |
| 32 | MP0003077_abnormal_cell_cycle | 1.42490162 |
| 33 | MP0002638_abnormal_pupillary_reflex | 1.39539346 |
| 34 | MP0006072_abnormal_retinal_apoptosis | 1.36115703 |
| 35 | MP0008007_abnormal_cellular_replicative | 1.33379484 |
| 36 | MP0002132_abnormal_respiratory_system | 1.30880900 |
| 37 | MP0008875_abnormal_xenobiotic_pharmacok | 1.26795242 |
| 38 | MP0005377_hearing/vestibular/ear_phenot | 1.26642775 |
| 39 | MP0003878_abnormal_ear_physiology | 1.26642775 |
| 40 | MP0004215_abnormal_myocardial_fiber | 1.26500209 |
| 41 | MP0000013_abnormal_adipose_tissue | 1.24300818 |
| 42 | MP0001929_abnormal_gametogenesis | 1.22044342 |
| 43 | MP0005075_abnormal_melanosome_morpholog | 1.21912322 |
| 44 | MP0010307_abnormal_tumor_latency | 1.21167796 |
| 45 | MP0005174_abnormal_tail_pigmentation | 1.21133412 |
| 46 | MP0003943_abnormal_hepatobiliary_system | 1.19004130 |
| 47 | MP0000372_irregular_coat_pigmentation | 1.18041781 |
| 48 | MP0002210_abnormal_sex_determination | 1.17413175 |
| 49 | MP0000678_abnormal_parathyroid_gland | 1.14190139 |
| 50 | MP0000015_abnormal_ear_pigmentation | 1.14105437 |
| 51 | MP0000358_abnormal_cell_content/ | 1.11458823 |
| 52 | MP0002095_abnormal_skin_pigmentation | 1.10497658 |
| 53 | MP0000313_abnormal_cell_death | 1.06936005 |
| 54 | MP0004043_abnormal_pH_regulation | 1.05763979 |
| 55 | MP0003950_abnormal_plasma_membrane | 1.02995217 |
| 56 | MP0001697_abnormal_embryo_size | 1.01910492 |
| 57 | MP0004084_abnormal_cardiac_muscle | 1.01607046 |
| 58 | MP0003186_abnormal_redox_activity | 1.00136832 |
| 59 | MP0005646_abnormal_pituitary_gland | 0.99669050 |
| 60 | MP0001145_abnormal_male_reproductive | 0.97368272 |
| 61 | MP0000653_abnormal_sex_gland | 0.95135212 |
| 62 | MP0004957_abnormal_blastocyst_morpholog | 0.93683447 |
| 63 | MP0005645_abnormal_hypothalamus_physiol | 0.91891184 |
| 64 | MP0001881_abnormal_mammary_gland | 0.89534710 |
| 65 | MP0009703_decreased_birth_body | 0.88247389 |
| 66 | MP0001661_extended_life_span | 0.86763564 |
| 67 | MP0005464_abnormal_platelet_physiology | 0.86275343 |
| 68 | MP0001293_anophthalmia | 0.85957091 |
| 69 | MP0009046_muscle_twitch | 0.85578320 |
| 70 | MP0005551_abnormal_eye_electrophysiolog | 0.83746268 |
| 71 | MP0004133_heterotaxia | 0.83383779 |
| 72 | MP0001730_embryonic_growth_arrest | 0.82426611 |
| 73 | MP0003698_abnormal_male_reproductive | 0.81937460 |
| 74 | MP0005266_abnormal_metabolism | 0.80865599 |
| 75 | MP0005647_abnormal_sex_gland | 0.79863194 |
| 76 | MP0001486_abnormal_startle_reflex | 0.79012590 |
| 77 | MP0002139_abnormal_hepatobiliary_system | 0.77948635 |
| 78 | MP0005389_reproductive_system_phenotype | 0.76853158 |
| 79 | MP0005253_abnormal_eye_physiology | 0.76178584 |
| 80 | MP0008961_abnormal_basal_metabolism | 0.73103504 |
| 81 | MP0005085_abnormal_gallbladder_physiolo | 0.72609687 |
| 82 | MP0008932_abnormal_embryonic_tissue | 0.72472433 |
| 83 | MP0003646_muscle_fatigue | 0.72070392 |
| 84 | MP0004264_abnormal_extraembryonic_tissu | 0.71898754 |
| 85 | MP0002019_abnormal_tumor_incidence | 0.69560836 |
| 86 | MP0001853_heart_inflammation | 0.68630377 |
| 87 | MP0009379_abnormal_foot_pigmentation | 0.67267424 |
| 88 | MP0000631_abnormal_neuroendocrine_gland | 0.63236633 |
| 89 | MP0004019_abnormal_vitamin_homeostasis | 0.61082381 |
| 90 | MP0005451_abnormal_body_composition | 0.61052116 |
| 91 | MP0002084_abnormal_developmental_patter | 0.60917482 |
| 92 | MP0003806_abnormal_nucleotide_metabolis | 0.60871141 |
| 93 | MP0003252_abnormal_bile_duct | 0.60610828 |
| 94 | MP0003303_peritoneal_inflammation | 0.60323041 |
| 95 | MP0002332_abnormal_exercise_endurance | 0.57503773 |
| 96 | MP0003984_embryonic_growth_retardation | 0.57456363 |
| 97 | MP0009765_abnormal_xenobiotic_induced | 0.56008719 |
| 98 | MP0003724_increased_susceptibility_to | 0.55510602 |
| 99 | MP0000516_abnormal_urinary_system | 0.55121239 |
| 100 | MP0005367_renal/urinary_system_phenotyp | 0.55121239 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Chromsome breakage (HP:0040012) | 6.98195379 |
| 2 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 4.79511840 |
| 3 | Abnormality of chromosome stability (HP:0003220) | 4.74004717 |
| 4 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 4.34282092 |
| 5 | Congenital stationary night blindness (HP:0007642) | 4.30951056 |
| 6 | Meckel diverticulum (HP:0002245) | 4.15976951 |
| 7 | Abnormality of the ileum (HP:0001549) | 3.84682246 |
| 8 | Abnormality of the preputium (HP:0100587) | 3.74745054 |
| 9 | Small intestinal stenosis (HP:0012848) | 3.68799877 |
| 10 | Duodenal stenosis (HP:0100867) | 3.68799877 |
| 11 | Central scotoma (HP:0000603) | 3.45087920 |
| 12 | Thrombocytosis (HP:0001894) | 3.28617971 |
| 13 | Eosinophilia (HP:0001880) | 3.21248970 |
| 14 | Clubbing of toes (HP:0100760) | 3.17499537 |
| 15 | Pancreatic fibrosis (HP:0100732) | 3.02956462 |
| 16 | Decreased central vision (HP:0007663) | 2.98957238 |
| 17 | Nephronophthisis (HP:0000090) | 2.96992760 |
| 18 | Abnormality of the duodenum (HP:0002246) | 2.92437219 |
| 19 | Granulocytopenia (HP:0001913) | 2.88195634 |
| 20 | Pancreatic cysts (HP:0001737) | 2.85894142 |
| 21 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 2.83698567 |
| 22 | Constricted visual fields (HP:0001133) | 2.83310626 |
| 23 | Birth length less than 3rd percentile (HP:0003561) | 2.81802233 |
| 24 | Abnormality of the renal medulla (HP:0100957) | 2.77183646 |
| 25 | Dyschromatopsia (HP:0007641) | 2.76047705 |
| 26 | Abnormality of the carotid arteries (HP:0005344) | 2.74314035 |
| 27 | True hermaphroditism (HP:0010459) | 2.73059752 |
| 28 | Cone-rod dystrophy (HP:0000548) | 2.68388966 |
| 29 | Biliary tract neoplasm (HP:0100574) | 2.56805376 |
| 30 | Neoplasm of the small intestine (HP:0100833) | 2.53862407 |
| 31 | Arteriovenous malformation (HP:0100026) | 2.49157071 |
| 32 | Type II lissencephaly (HP:0007260) | 2.48776860 |
| 33 | Myelodysplasia (HP:0002863) | 2.46436496 |
| 34 | Acute encephalopathy (HP:0006846) | 2.45681530 |
| 35 | Periodontitis (HP:0000704) | 2.40667934 |
| 36 | Progressive muscle weakness (HP:0003323) | 2.36253276 |
| 37 | Sloping forehead (HP:0000340) | 2.35531614 |
| 38 | Attenuation of retinal blood vessels (HP:0007843) | 2.31549730 |
| 39 | Rhabdomyosarcoma (HP:0002859) | 2.29986077 |
| 40 | Sclerocornea (HP:0000647) | 2.29542998 |
| 41 | Progressive macrocephaly (HP:0004481) | 2.27860587 |
| 42 | Optic disc pallor (HP:0000543) | 2.25438939 |
| 43 | Dyskinesia (HP:0100660) | 2.24896093 |
| 44 | Absent thumb (HP:0009777) | 2.18613405 |
| 45 | Abnormality of eosinophils (HP:0001879) | 2.14985394 |
| 46 | Duplicated collecting system (HP:0000081) | 2.13226216 |
| 47 | Type I transferrin isoform profile (HP:0003642) | 2.12938490 |
| 48 | Neoplasm of the rectum (HP:0100743) | 2.12129448 |
| 49 | Neurodegeneration (HP:0002180) | 2.11612231 |
| 50 | Short middle phalanx of the 5th finger (HP:0004220) | 2.09209800 |
| 51 | Increased CSF lactate (HP:0002490) | 2.08229875 |
| 52 | Scotoma (HP:0000575) | 2.06363439 |
| 53 | Poikilocytosis (HP:0004447) | 2.06218469 |
| 54 | Hepatocellular necrosis (HP:0001404) | 2.06175818 |
| 55 | Cerebellar dysplasia (HP:0007033) | 2.05468541 |
| 56 | Acanthocytosis (HP:0001927) | 2.04670105 |
| 57 | Acute myeloid leukemia (HP:0004808) | 2.04261355 |
| 58 | Acute necrotizing encephalopathy (HP:0006965) | 2.04259391 |
| 59 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.04214348 |
| 60 | Ectopic kidney (HP:0000086) | 2.03963354 |
| 61 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.03718672 |
| 62 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.03718672 |
| 63 | Abnormal protein glycosylation (HP:0012346) | 2.03718672 |
| 64 | Abnormal glycosylation (HP:0012345) | 2.03718672 |
| 65 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.03556263 |
| 66 | Hypoplasia of the pons (HP:0012110) | 2.03458784 |
| 67 | Genetic anticipation (HP:0003743) | 2.01588900 |
| 68 | Oligohydramnios (HP:0001562) | 2.00863934 |
| 69 | Macular degeneration (HP:0000608) | 1.98471128 |
| 70 | Increased serum lactate (HP:0002151) | 1.97971358 |
| 71 | Pigmentary retinal degeneration (HP:0001146) | 1.97683274 |
| 72 | Abnormality of the pons (HP:0007361) | 1.96745034 |
| 73 | Abnormality of midbrain morphology (HP:0002418) | 1.96576926 |
| 74 | Molar tooth sign on MRI (HP:0002419) | 1.96576926 |
| 75 | Abnormality of macular pigmentation (HP:0008002) | 1.95707937 |
| 76 | Nephroblastoma (Wilms tumor) (HP:0002667) | 1.94404721 |
| 77 | Progressive inability to walk (HP:0002505) | 1.92888805 |
| 78 | Ureteral duplication (HP:0000073) | 1.91830938 |
| 79 | Abnormality of the renal cortex (HP:0011035) | 1.91248847 |
| 80 | Abnormality of the renal collecting system (HP:0004742) | 1.90912331 |
| 81 | Bone marrow hypocellularity (HP:0005528) | 1.90213092 |
| 82 | Autoimmune thrombocytopenia (HP:0001973) | 1.89129877 |
| 83 | Hyperthyroidism (HP:0000836) | 1.86899671 |
| 84 | Astigmatism (HP:0000483) | 1.86776755 |
| 85 | Keratoconus (HP:0000563) | 1.85685329 |
| 86 | Increased corneal curvature (HP:0100692) | 1.85685329 |
| 87 | Reduced antithrombin III activity (HP:0001976) | 1.85653966 |
| 88 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.83681492 |
| 89 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.83681492 |
| 90 | 3-Methylglutaconic aciduria (HP:0003535) | 1.83664018 |
| 91 | Fair hair (HP:0002286) | 1.83572455 |
| 92 | Pili torti (HP:0003777) | 1.83280732 |
| 93 | Renal cortical cysts (HP:0000803) | 1.82404064 |
| 94 | Abnormality of B cell number (HP:0010975) | 1.82395077 |
| 95 | Embryonal renal neoplasm (HP:0011794) | 1.81978869 |
| 96 | Aplasia/Hypoplasia of the earlobes (HP:0009906) | 1.81177187 |
| 97 | Mitochondrial inheritance (HP:0001427) | 1.81161485 |
| 98 | Triphalangeal thumb (HP:0001199) | 1.80750901 |
| 99 | Bile duct proliferation (HP:0001408) | 1.77552930 |
| 100 | Abnormal biliary tract physiology (HP:0012439) | 1.77552930 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TAOK3 | 6.00958641 |
| 2 | MST4 | 3.39258276 |
| 3 | PIK3CG | 3.11745024 |
| 4 | FRK | 2.92575634 |
| 5 | PDK2 | 2.91905131 |
| 6 | PBK | 2.66908870 |
| 7 | SRPK1 | 2.52399781 |
| 8 | NUAK1 | 2.48771628 |
| 9 | TNIK | 2.43052978 |
| 10 | CSNK1G3 | 2.28061632 |
| 11 | PIK3CA | 2.24464555 |
| 12 | STK16 | 2.18005523 |
| 13 | CSNK1A1L | 2.16378211 |
| 14 | TTK | 2.10752262 |
| 15 | CCNB1 | 2.06034983 |
| 16 | PLK4 | 1.99128120 |
| 17 | IRAK1 | 1.93623150 |
| 18 | CDK3 | 1.81455512 |
| 19 | ZAK | 1.76051109 |
| 20 | CSNK1G2 | 1.75314376 |
| 21 | TRPM7 | 1.69364828 |
| 22 | CSNK1G1 | 1.66180108 |
| 23 | ERBB3 | 1.63960452 |
| 24 | MKNK1 | 1.63704626 |
| 25 | MKNK2 | 1.63550211 |
| 26 | BRSK2 | 1.61935690 |
| 27 | IRAK3 | 1.56855459 |
| 28 | IRAK2 | 1.55660699 |
| 29 | EIF2AK1 | 1.51782559 |
| 30 | CHEK2 | 1.48592971 |
| 31 | ATR | 1.43860725 |
| 32 | CDC7 | 1.36225778 |
| 33 | BUB1 | 1.33073667 |
| 34 | BMPR1B | 1.23473271 |
| 35 | BMPR2 | 1.14806657 |
| 36 | ACVR1B | 1.11928382 |
| 37 | RIPK4 | 1.11672139 |
| 38 | NEK2 | 1.10419294 |
| 39 | CAMK1D | 1.07886111 |
| 40 | TSSK6 | 1.07401505 |
| 41 | PLK3 | 1.04512156 |
| 42 | WEE1 | 0.99536447 |
| 43 | PINK1 | 0.98714157 |
| 44 | CDK19 | 0.95096063 |
| 45 | NME1 | 0.92100898 |
| 46 | PLK1 | 0.91163779 |
| 47 | CLK1 | 0.88902444 |
| 48 | MAP3K4 | 0.87273926 |
| 49 | TLK1 | 0.81572249 |
| 50 | RPS6KB2 | 0.81137614 |
| 51 | ATM | 0.77429658 |
| 52 | KIT | 0.74473806 |
| 53 | VRK1 | 0.74157276 |
| 54 | IRAK4 | 0.59802918 |
| 55 | MST1R | 0.58261173 |
| 56 | CSNK2A2 | 0.56640585 |
| 57 | CSNK1E | 0.56459544 |
| 58 | AURKB | 0.54801076 |
| 59 | OBSCN | 0.54001288 |
| 60 | LATS1 | 0.53321893 |
| 61 | ERBB4 | 0.52969158 |
| 62 | MATK | 0.50721905 |
| 63 | CDK9 | 0.50409112 |
| 64 | CHEK1 | 0.50129136 |
| 65 | ADRBK2 | 0.49243740 |
| 66 | WNK4 | 0.47205676 |
| 67 | CSNK2A1 | 0.47121635 |
| 68 | GRK1 | 0.46922238 |
| 69 | TEC | 0.46299756 |
| 70 | CSNK1D | 0.46003141 |
| 71 | RPS6KA4 | 0.45215590 |
| 72 | DAPK2 | 0.44580249 |
| 73 | RAF1 | 0.44093153 |
| 74 | PTK2B | 0.43269389 |
| 75 | PRKG2 | 0.39886035 |
| 76 | PTK6 | 0.39673068 |
| 77 | PRKDC | 0.39049100 |
| 78 | TGFBR1 | 0.37763275 |
| 79 | PLK2 | 0.37538912 |
| 80 | CDK1 | 0.36213631 |
| 81 | FLT3 | 0.36170865 |
| 82 | PRKAA2 | 0.35846553 |
| 83 | FGFR1 | 0.35609128 |
| 84 | BMX | 0.35073984 |
| 85 | PRKCQ | 0.34953629 |
| 86 | CDK2 | 0.34384128 |
| 87 | TYK2 | 0.31824337 |
| 88 | KSR2 | 0.31034371 |
| 89 | PHKG1 | 0.30826378 |
| 90 | PHKG2 | 0.30826378 |
| 91 | PRKAA1 | 0.29842145 |
| 92 | CSNK1A1 | 0.28447759 |
| 93 | STK4 | 0.27575152 |
| 94 | NEK1 | 0.27057564 |
| 95 | CAMK1G | 0.25996343 |
| 96 | CDK7 | 0.25846364 |
| 97 | GSK3B | 0.24258890 |
| 98 | CAMKK2 | 0.23504073 |
| 99 | VRK2 | 0.23319510 |
| 100 | CDK4 | 0.23191643 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Non-homologous end-joining_Homo sapiens_hsa03450 | 5.75106122 |
| 2 | Homologous recombination_Homo sapiens_hsa03440 | 5.10508056 |
| 3 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 3.85387648 |
| 4 | Olfactory transduction_Homo sapiens_hsa04740 | 3.65979009 |
| 5 | Mismatch repair_Homo sapiens_hsa03430 | 3.07230593 |
| 6 | DNA replication_Homo sapiens_hsa03030 | 2.74597009 |
| 7 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.64687864 |
| 8 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.53445865 |
| 9 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.48823922 |
| 10 | Base excision repair_Homo sapiens_hsa03410 | 2.34508156 |
| 11 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 2.19835605 |
| 12 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.09289319 |
| 13 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.08098139 |
| 14 | Ribosome_Homo sapiens_hsa03010 | 1.89587567 |
| 15 | RNA polymerase_Homo sapiens_hsa03020 | 1.88213259 |
| 16 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.83098282 |
| 17 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.80091797 |
| 18 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.77196253 |
| 19 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.64356975 |
| 20 | RNA transport_Homo sapiens_hsa03013 | 1.58805942 |
| 21 | Parkinsons disease_Homo sapiens_hsa05012 | 1.51903999 |
| 22 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.51085680 |
| 23 | Spliceosome_Homo sapiens_hsa03040 | 1.50627681 |
| 24 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.47832474 |
| 25 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.44532595 |
| 26 | Basal transcription factors_Homo sapiens_hsa03022 | 1.44287787 |
| 27 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.36249472 |
| 28 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.26069753 |
| 29 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.23430147 |
| 30 | Huntingtons disease_Homo sapiens_hsa05016 | 1.15376317 |
| 31 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.13102032 |
| 32 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.13000746 |
| 33 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.12603415 |
| 34 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.11268545 |
| 35 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.08427380 |
| 36 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.08144225 |
| 37 | Purine metabolism_Homo sapiens_hsa00230 | 1.07453698 |
| 38 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.06928865 |
| 39 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.00179088 |
| 40 | Alzheimers disease_Homo sapiens_hsa05010 | 0.93904795 |
| 41 | RNA degradation_Homo sapiens_hsa03018 | 0.91741332 |
| 42 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.91243034 |
| 43 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.90382837 |
| 44 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.84380404 |
| 45 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.83698994 |
| 46 | Proteasome_Homo sapiens_hsa03050 | 0.82658023 |
| 47 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.82053438 |
| 48 | Cell cycle_Homo sapiens_hsa04110 | 0.78929542 |
| 49 | Peroxisome_Homo sapiens_hsa04146 | 0.74866858 |
| 50 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.74180295 |
| 51 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.73370253 |
| 52 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.69533013 |
| 53 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.68789088 |
| 54 | Metabolic pathways_Homo sapiens_hsa01100 | 0.65236700 |
| 55 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.64661823 |
| 56 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.63843673 |
| 57 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.61246696 |
| 58 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.59122224 |
| 59 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.59119677 |
| 60 | Carbon metabolism_Homo sapiens_hsa01200 | 0.57114819 |
| 61 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.45494734 |
| 62 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.44788231 |
| 63 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.38252441 |
| 64 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.35372257 |
| 65 | Taste transduction_Homo sapiens_hsa04742 | 0.34050949 |
| 66 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.33925375 |
| 67 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.33809859 |
| 68 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.31099213 |
| 69 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.31095528 |
| 70 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.29919099 |
| 71 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.29879056 |
| 72 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.29836001 |
| 73 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.29471168 |
| 74 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.29100782 |
| 75 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.28641980 |
| 76 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.26782597 |
| 77 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.25290816 |
| 78 | Mineral absorption_Homo sapiens_hsa04978 | 0.24370796 |
| 79 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.22803353 |
| 80 | Platelet activation_Homo sapiens_hsa04611 | 0.21751291 |
| 81 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.21700351 |
| 82 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.20696802 |
| 83 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.19512347 |
| 84 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.19435129 |
| 85 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.19316577 |
| 86 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.17578196 |
| 87 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.17227604 |
| 88 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.15850857 |
| 89 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.13637357 |
| 90 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.13033751 |
| 91 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.12667984 |
| 92 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.12267104 |
| 93 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.11931019 |
| 94 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.11700405 |
| 95 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.08934032 |
| 96 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.08262178 |
| 97 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.06961227 |
| 98 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.06344355 |
| 99 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.06268799 |
| 100 | Long-term depression_Homo sapiens_hsa04730 | 0.04773721 |

