OR5P1P

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ventricular system development (GO:0021591)9.47924412
2regulation of cilium movement (GO:0003352)8.13713231
3left/right pattern formation (GO:0060972)6.54454161
4microtubule bundle formation (GO:0001578)6.50243030
5photoreceptor cell maintenance (GO:0045494)5.87557048
6left/right axis specification (GO:0070986)5.76885097
7hepatocyte differentiation (GO:0070365)5.41322852
8cilium organization (GO:0044782)5.00465618
9regulation of DNA endoreduplication (GO:0032875)4.69090981
10eye photoreceptor cell development (GO:0042462)4.62114604
11regulation of microtubule-based movement (GO:0060632)4.61757659
12microtubule depolymerization (GO:0007019)4.53975044
13microtubule-based movement (GO:0007018)4.49930745
14photoreceptor cell development (GO:0042461)4.45593339
15brain morphogenesis (GO:0048854)4.42588548
16fat-soluble vitamin biosynthetic process (GO:0042362)4.32946821
17phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)4.17596851
18lateral ventricle development (GO:0021670)4.11629245
19oxidative demethylation (GO:0070989)4.06680004
20cilium assembly (GO:0042384)4.01765571
21cellular component assembly involved in morphogenesis (GO:0010927)3.94797186
22cilium morphogenesis (GO:0060271)3.89554727
23protein localization to microtubule cytoskeleton (GO:0072698)3.76414037
24peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)3.75773299
25ubiquinone biosynthetic process (GO:0006744)3.75583544
26intraciliary transport (GO:0042073)3.63759986
27multicellular organismal aging (GO:0010259)3.62336546
28peristalsis (GO:0030432)3.60017446
29protein localization to cilium (GO:0061512)3.50209242
30positive regulation of DNA-dependent DNA replication (GO:2000105)3.36992549
31cell projection assembly (GO:0030031)3.36596878
32ubiquinone metabolic process (GO:0006743)3.34524257
33protein localization to cytoskeleton (GO:0044380)3.27958200
34microtubule polymerization or depolymerization (GO:0031109)3.21861209
35quinone biosynthetic process (GO:1901663)3.19013526
36determination of left/right symmetry (GO:0007368)3.16978697
37lateral sprouting from an epithelium (GO:0060601)3.08527935
38determination of bilateral symmetry (GO:0009855)3.08455641
39negative regulation of translation, ncRNA-mediated (GO:0040033)3.04634930
40regulation of translation, ncRNA-mediated (GO:0045974)3.04634930
41negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.04634930
42specification of symmetry (GO:0009799)3.01330359
43cilium or flagellum-dependent cell motility (GO:0001539)21.7842391
44regulation of interleukin-5 production (GO:0032674)2.95576948
45trophoblast giant cell differentiation (GO:0060707)2.92019751
46regulation of establishment of planar polarity (GO:0090175)2.89428394
47axis elongation (GO:0003401)2.89411559
48microtubule severing (GO:0051013)2.86462327
49maintenance of gastrointestinal epithelium (GO:0030277)2.84892493
50kidney morphogenesis (GO:0060993)2.82831403
51lysine catabolic process (GO:0006554)2.76667769
52lysine metabolic process (GO:0006553)2.76667769
53positive regulation of urine volume (GO:0035810)2.76073073
54Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.74213679
55microtubule-based process (GO:0007017)2.72946623
56interkinetic nuclear migration (GO:0022027)2.72778694
57single strand break repair (GO:0000012)2.65160132
58synaptic vesicle docking involved in exocytosis (GO:0016081)2.61316325
59early endosome to late endosome transport (GO:0045022)2.60033629
60multicellular organismal reproductive behavior (GO:0033057)2.50854689
61oxygen transport (GO:0015671)2.46688483
62kynurenine metabolic process (GO:0070189)2.46164187
63pericardium development (GO:0060039)2.42582889
64heart looping (GO:0001947)2.42095933
65O-glycan processing (GO:0016266)2.40194171
66snRNA processing (GO:0016180)2.37085881
67indolalkylamine catabolic process (GO:0046218)2.36208035
68tryptophan catabolic process (GO:0006569)2.36208035
69indole-containing compound catabolic process (GO:0042436)2.36208035
70nonmotile primary cilium assembly (GO:0035058)2.35897601
71exogenous drug catabolic process (GO:0042738)2.33371371
72ncRNA 3-end processing (GO:0043628)2.32430188
73regulation of transforming growth factor beta1 production (GO:0032908)2.25877754
74myoblast migration (GO:0051451)2.24335866
75regulation of urine volume (GO:0035809)2.19712591
76regulation of DNA methylation (GO:0044030)2.19558100
77regulation of skeletal muscle contraction (GO:0014819)2.16034065
78positive regulation by symbiont of host defense response (GO:0052509)2.15402236
79modulation by symbiont of host defense response (GO:0052031)2.15402236
80modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.15402236
81modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.15402236
82positive regulation by organism of defense response of other organism involved in symbiotic interact2.15402236
83modulation by symbiont of host immune response (GO:0052553)2.15402236
84snRNA transcription (GO:0009301)2.15026876
85snRNA metabolic process (GO:0016073)2.13867656
86cellular response to exogenous dsRNA (GO:0071360)2.12113301
87positive regulation of megakaryocyte differentiation (GO:0045654)2.11954549
88metanephric mesenchyme development (GO:0072075)2.11349794
89positive regulation of heterotypic cell-cell adhesion (GO:0034116)2.10922379
90macrophage activation involved in immune response (GO:0002281)2.10397651
91T-helper 1 type immune response (GO:0042088)2.09899893
92embryonic heart tube morphogenesis (GO:0003143)2.08170105
93epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)17.3515106
94retinal cone cell development (GO:0046549)15.5131094
95cilium movement (GO:0003341)15.3810206
96retinal rod cell development (GO:0046548)15.2646325
97motile cilium assembly (GO:0044458)14.6141133
98axoneme assembly (GO:0035082)14.5916796
99axonemal dynein complex assembly (GO:0070286)14.0147260
100epithelial cilium movement (GO:0003351)12.0126275

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse9.24598284
2AR_21572438_ChIP-Seq_LNCaP_Human5.05551283
3BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse4.98269028
4STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse4.68434101
5IGF1R_20145208_ChIP-Seq_DFB_Human3.70937981
6FLI1_27457419_Chip-Seq_LIVER_Mouse2.33156988
7EZH2_22144423_ChIP-Seq_EOC_Human2.23685278
8AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human2.08916639
9PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.06360558
10CBP_20019798_ChIP-Seq_JUKART_Human2.04542441
11IRF4_20064451_ChIP-Seq_CD4+T_Mouse2.04542441
12CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.03610795
13SMAD4_21799915_ChIP-Seq_A2780_Human2.03118359
14TP53_16413492_ChIP-PET_HCT116_Human2.02932682
15FOXM1_26456572_ChIP-Seq_MCF-7_Human2.01493884
16SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.98440788
17TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.97757265
18DROSHA_22980978_ChIP-Seq_HELA_Human1.94116668
19TOP2B_26459242_ChIP-Seq_MCF-7_Human1.86507708
20VDR_22108803_ChIP-Seq_LS180_Human1.77156330
21GBX2_23144817_ChIP-Seq_PC3_Human1.76829858
22PIAS1_25552417_ChIP-Seq_VCAP_Human1.76483442
23ARNT_22903824_ChIP-Seq_MCF-7_Human1.73615589
24CTBP1_25329375_ChIP-Seq_LNCAP_Human1.71979231
25SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.70937907
26CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.70500355
27AHR_22903824_ChIP-Seq_MCF-7_Human1.70037640
28PCGF2_27294783_Chip-Seq_ESCs_Mouse1.69254189
29FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.69039581
30STAT3_23295773_ChIP-Seq_U87_Human1.65780365
31SMAD3_21741376_ChIP-Seq_EPCs_Human1.64870260
32EP300_21415370_ChIP-Seq_HL-1_Mouse1.58374610
33TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.57865778
34GATA1_26923725_Chip-Seq_HPCs_Mouse1.52516338
35ZNF217_24962896_ChIP-Seq_MCF-7_Human1.50161993
36GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.47820253
37CTBP2_25329375_ChIP-Seq_LNCAP_Human1.45483609
38NR3C1_21868756_ChIP-Seq_MCF10A_Human1.45032237
39PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.44392360
40SMRT_27268052_Chip-Seq_Bcells_Human1.42106268
41STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.41760767
42SMAD4_21741376_ChIP-Seq_EPCs_Human1.38959454
43NFE2_27457419_Chip-Seq_LIVER_Mouse1.38658511
44EWS_26573619_Chip-Seq_HEK293_Human1.37089687
45FUS_26573619_Chip-Seq_HEK293_Human1.36699154
46PRDM14_20953172_ChIP-Seq_ESCs_Human1.36499412
47POU3F2_20337985_ChIP-ChIP_501MEL_Human1.34864923
48SOX2_19829295_ChIP-Seq_ESCs_Human1.30780000
49NANOG_19829295_ChIP-Seq_ESCs_Human1.30780000
50SUZ12_27294783_Chip-Seq_NPCs_Mouse1.30082855
51RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human1.28765301
52ERG_20517297_ChIP-Seq_VCAP_Human1.26159604
53TCF4_23295773_ChIP-Seq_U87_Human1.25116024
54TP53_22573176_ChIP-Seq_HFKS_Human1.24083665
55BCAT_22108803_ChIP-Seq_LS180_Human1.22155202
56ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.20806541
57ELK4_26923725_Chip-Seq_MESODERM_Mouse1.19990835
58MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.19716369
59TAF15_26573619_Chip-Seq_HEK293_Human1.19318458
60AR_20517297_ChIP-Seq_VCAP_Human1.18826555
61GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human1.16247397
62CTNNB1_20460455_ChIP-Seq_HCT116_Human1.15121136
63TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.13717821
64TCF4_22108803_ChIP-Seq_LS180_Human1.13171591
65AR_25329375_ChIP-Seq_VCAP_Human1.12422800
66RUNX2_22187159_ChIP-Seq_PCA_Human1.11072742
67STAT6_21828071_ChIP-Seq_BEAS2B_Human1.10972626
68EZH2_27294783_Chip-Seq_NPCs_Mouse1.10761674
69ER_23166858_ChIP-Seq_MCF-7_Human1.09962216
70AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.09502742
71RNF2_27304074_Chip-Seq_NSC_Mouse1.09237576
72ZNF274_21170338_ChIP-Seq_K562_Hela1.07871013
73KDM2B_26808549_Chip-Seq_REH_Human1.06653987
74FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.05380983
75SMAD3_21741376_ChIP-Seq_HESCs_Human1.02542175
76P300_19829295_ChIP-Seq_ESCs_Human1.02151896
77SMAD4_21741376_ChIP-Seq_HESCs_Human1.01810854
78ESR1_20079471_ChIP-ChIP_T-47D_Human0.97771413
79UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.96976448
80EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.94379287
81FOXA1_25552417_ChIP-Seq_VCAP_Human0.93818583
82GATA4_25053715_ChIP-Seq_YYC3_Human0.92048385
83TBL1_22424771_ChIP-Seq_293T_Human0.91171899
84ZFP57_27257070_Chip-Seq_ESCs_Mouse0.90676520
85SOX2_21211035_ChIP-Seq_LN229_Gbm0.90602567
86SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.90558754
87CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.90274245
88FOXA1_21572438_ChIP-Seq_LNCaP_Human0.89118536
89KLF5_20875108_ChIP-Seq_MESCs_Mouse0.88246999
90CDX2_22108803_ChIP-Seq_LS180_Human0.87842055
91VDR_24787735_ChIP-Seq_THP-1_Human0.87818121
92TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.87724344
93TP53_18474530_ChIP-ChIP_U2OS_Human0.86264586
94TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.85705279
95AUTS2_25519132_ChIP-Seq_293T-REX_Human0.84885641
96SMAD3_21741376_ChIP-Seq_ESCs_Human0.83958198
97PCGF4_22325352_ChIP-Seq_293T-Rex_Human0.83745071
98NFYA_21822215_ChIP-Seq_K562_Human0.83606159
99TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.83236845
100SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.82736300

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002653_abnormal_ependyma_morphology7.76914467
2MP0005623_abnormal_meninges_morphology5.47579187
3MP0005253_abnormal_eye_physiology4.22346966
4MP0005083_abnormal_biliary_tract3.96143804
5MP0001346_abnormal_lacrimal_gland3.74181241
6MP0008057_abnormal_DNA_replication3.67106773
7MP0004043_abnormal_pH_regulation3.20378007
8MP0005551_abnormal_eye_electrophysiolog2.97308184
9MP0003950_abnormal_plasma_membrane2.88338934
10MP0000383_abnormal_hair_follicle2.76872532
11MP0010368_abnormal_lymphatic_system2.60763772
12MP0003718_maternal_effect2.53354386
13MP0003878_abnormal_ear_physiology2.36906321
14MP0005377_hearing/vestibular/ear_phenot2.36906321
15MP0010678_abnormal_skin_adnexa2.17297219
16MP0003195_calcinosis2.05603759
17MP0008961_abnormal_basal_metabolism1.89269354
18MP0008875_abnormal_xenobiotic_pharmacok1.87638986
19MP0005195_abnormal_posterior_eye1.85430296
20MP0005395_other_phenotype1.75142457
21MP0005391_vision/eye_phenotype1.74675942
22MP0002282_abnormal_trachea_morphology1.61087565
23MP0005085_abnormal_gallbladder_physiolo1.57412157
24MP0009115_abnormal_fat_cell1.55642800
25MP0001661_extended_life_span1.55446308
26MP0004145_abnormal_muscle_electrophysio1.53516437
27MP0005360_urolithiasis1.47261936
28MP0008995_early_reproductive_senescence1.46963934
29MP0009046_muscle_twitch1.42017462
30MP0000427_abnormal_hair_cycle1.41654260
31MP0000631_abnormal_neuroendocrine_gland1.37605720
32MP0003959_abnormal_lean_body1.35567704
33MP0001666_abnormal_nutrient_absorption1.35559438
34MP0005646_abnormal_pituitary_gland1.32830803
35MP0000569_abnormal_digit_pigmentation1.31184217
36MP0002168_other_aberrant_phenotype1.29243441
37MP0003646_muscle_fatigue1.26888988
38MP0009643_abnormal_urine_homeostasis1.25107544
39MP0010030_abnormal_orbit_morphology1.21974280
40MP0003045_fibrosis1.20590703
41MP0002160_abnormal_reproductive_system1.18943238
42MP0004133_heterotaxia1.18937456
43MP0010329_abnormal_lipoprotein_level1.18883867
44MP0002277_abnormal_respiratory_mucosa1.17149002
45MP0002108_abnormal_muscle_morphology1.10565430
46MP0001324_abnormal_eye_pigmentation1.10011054
47MP0000566_synostosis1.09373233
48MP0001963_abnormal_hearing_physiology1.08080900
49MP0002229_neurodegeneration1.05643644
50MP0001879_abnormal_lymphatic_vessel1.04983546
51MP0005387_immune_system_phenotype0.97377237
52MP0001790_abnormal_immune_system0.97377237
53MP0005503_abnormal_tendon_morphology0.92277096
54MP0002135_abnormal_kidney_morphology0.91645168
55MP0002405_respiratory_system_inflammati0.89361864
56MP0005248_abnormal_Harderian_gland0.88428967
57MP0001851_eye_inflammation0.86719394
58MP0001929_abnormal_gametogenesis0.86354820
59MP0005220_abnormal_exocrine_pancreas0.84892085
60MP0009840_abnormal_foam_cell0.84743722
61MP0002734_abnormal_mechanical_nocicepti0.84079558
62MP0002136_abnormal_kidney_physiology0.83435591
63MP0006082_CNS_inflammation0.80887983
64MP0001177_atelectasis0.79563692
65MP0001944_abnormal_pancreas_morphology0.75828836
66MP0005332_abnormal_amino_acid0.74056233
67MP0006138_congestive_heart_failure0.72391829
68MP0003690_abnormal_glial_cell0.69768523
69MP0001486_abnormal_startle_reflex0.68589999
70MP0001502_abnormal_circadian_rhythm0.67219384
71MP0002970_abnormal_white_adipose0.66120637
72MP0005388_respiratory_system_phenotype0.65487589
73MP0002133_abnormal_respiratory_system0.65487589
74MP0000653_abnormal_sex_gland0.63962090
75MP0005645_abnormal_hypothalamus_physiol0.63719883
76MP0000026_abnormal_inner_ear0.63306235
77MP0003137_abnormal_impulse_conducting0.61830840
78MP0002210_abnormal_sex_determination0.61023049
79MP0003935_abnormal_craniofacial_develop0.60865164
80MP0009765_abnormal_xenobiotic_induced0.60822244
81MP0002557_abnormal_social/conspecific_i0.59886284
82MP0009384_cardiac_valve_regurgitation0.58833489
83MP0004142_abnormal_muscle_tone0.58251989
84MP0005636_abnormal_mineral_homeostasis0.56658230
85MP0002909_abnormal_adrenal_gland0.54173192
86MP0003890_abnormal_embryonic-extraembry0.54057629
87MP0003699_abnormal_female_reproductive0.53286337
88MP0002118_abnormal_lipid_homeostasis0.52477822
89MP0001286_abnormal_eye_development0.51997839
90MP0008789_abnormal_olfactory_epithelium0.51151747
91MP0003698_abnormal_male_reproductive0.50985861
92MP0005389_reproductive_system_phenotype0.50421906
93MP0000767_abnormal_smooth_muscle0.47446922
94MP0001765_abnormal_ion_homeostasis0.47317328
95MP0000751_myopathy0.45581138
96MP0001119_abnormal_female_reproductive0.44892010
97MP0003119_abnormal_digestive_system0.43489443
98MP0000639_abnormal_adrenal_gland0.42847103
99MP0001145_abnormal_male_reproductive0.42571485
100MP0003861_abnormal_nervous_system0.42124205

Predicted human phenotypes

RankGene SetZ-score
1Absent rod-and cone-mediated responses on ERG (HP:0007688)9.94489812
2Abnormal ciliary motility (HP:0012262)9.60894179
3Respiratory insufficiency due to defective ciliary clearance (HP:0200073)9.26412861
4Abnormal respiratory motile cilium morphology (HP:0005938)8.54579277
5Abnormal respiratory epithelium morphology (HP:0012253)8.54579277
6Abnormal respiratory motile cilium physiology (HP:0012261)8.44216511
7Chronic hepatic failure (HP:0100626)6.22595390
8Chronic bronchitis (HP:0004469)6.10765693
9Abnormal rod and cone electroretinograms (HP:0008323)6.06472806
10Rhinitis (HP:0012384)5.70639693
11Tubulointerstitial nephritis (HP:0001970)5.58388287
12Bronchiectasis (HP:0002110)5.00131208
13Nasal polyposis (HP:0100582)4.88416897
14Bronchitis (HP:0012387)4.55724016
15Bony spicule pigmentary retinopathy (HP:0007737)4.21181434
16Constricted visual fields (HP:0001133)4.08761327
17Abnormality of the nasal mucosa (HP:0000433)4.01116604
18Recurrent bronchitis (HP:0002837)3.49132864
19Recurrent sinusitis (HP:0011108)3.34844246
20Cone-rod dystrophy (HP:0000548)3.28352981
21Recurrent otitis media (HP:0000403)3.20427355
22Menstrual irregularities (HP:0000858)3.12070663
23Hypoalphalipoproteinemia (HP:0003233)2.95587271
24Progressive sensorineural hearing impairment (HP:0000408)2.93209847
25Abnormal hair whorl (HP:0010721)2.91145384
26Chronic sinusitis (HP:0011109)2.90184279
27Renovascular hypertension (HP:0100817)2.78919851
28Hyperactive renin-angiotensin system (HP:0000841)2.63301998
29Abnormality of the fingertips (HP:0001211)2.60784056
30Decreased circulating renin level (HP:0003351)2.55619598
31Infertility (HP:0000789)2.47436643
32Tubulointerstitial abnormality (HP:0001969)2.38420392
33Long nose (HP:0003189)2.25033337
34Hyperuricemia (HP:0002149)2.23620977
35Increased purine levels (HP:0004368)2.23620977
36Supernumerary spleens (HP:0009799)2.22996439
37Insulin-resistant diabetes mellitus (HP:0000831)2.19390450
38Premature skin wrinkling (HP:0100678)2.13094974
39Aortic aneurysm (HP:0004942)2.10331826
40Nephronophthisis (HP:0000090)2.10170736
41Anteriorly placed anus (HP:0001545)2.07511551
42Abnormality of midbrain morphology (HP:0002418)2.03351792
43Molar tooth sign on MRI (HP:0002419)2.03351792
44Medial flaring of the eyebrow (HP:0010747)2.01135548
45Dynein arm defect of respiratory motile cilia (HP:0012255)13.8137702
46Absent/shortened dynein arms (HP:0200106)13.8137702
47Macroorchidism (HP:0000053)1.94340140
48Subcapsular cataract (HP:0000523)1.92432756
49Recurrent pneumonia (HP:0006532)1.86936818
50Partial agenesis of the corpus callosum (HP:0001338)1.85669074
51Abnormality of the renal medulla (HP:0100957)1.84135214
52Congenital primary aphakia (HP:0007707)1.76844770
53Gait imbalance (HP:0002141)1.73916233
54Portal hypertension (HP:0001409)1.72182883
55Progressive hearing impairment (HP:0001730)1.68012219
56Heterotopia (HP:0002282)1.67333409
57High pitched voice (HP:0001620)1.66443511
58Anal stenosis (HP:0002025)1.65481289
59Truncal obesity (HP:0001956)1.62479845
60Growth hormone deficiency (HP:0000824)1.59677736
61Nephrogenic diabetes insipidus (HP:0009806)1.59332664
62Hyperkalemia (HP:0002153)1.59294962
63Gingivitis (HP:0000230)1.55912944
64Abnormality of the hepatic vasculature (HP:0006707)1.55507962
65Renal salt wasting (HP:0000127)1.52273498
66Retinitis pigmentosa (HP:0000510)1.50321421
67Deep philtrum (HP:0002002)1.48495183
68Hypergonadotropic hypogonadism (HP:0000815)1.45784787
69Hepatitis (HP:0012115)1.44437175
70Hypolipoproteinemia (HP:0010981)1.41627294
71Hyperaldosteronism (HP:0000859)1.40076828
72Narrow nasal bridge (HP:0000446)1.39493032
73Occipital encephalocele (HP:0002085)1.37234933
74Genital tract atresia (HP:0001827)1.36156444
75Vaginal atresia (HP:0000148)1.36050773
76Obsessive-compulsive behavior (HP:0000722)1.34555839
77Hypokalemic alkalosis (HP:0001949)1.34347553
78Nephrocalcinosis (HP:0000121)1.32516352
79Abnormality of purine metabolism (HP:0004352)1.32166171
80Poor coordination (HP:0002370)1.31110797
81Recurrent lower respiratory tract infections (HP:0002783)1.28859138
82Large for gestational age (HP:0001520)1.28709339
83Abnormality of renin-angiotensin system (HP:0000847)1.27451044
84Impaired social interactions (HP:0000735)1.22694021
85Abnormal social behavior (HP:0012433)1.22694021
86Pancreatic fibrosis (HP:0100732)1.22217125
87Broad hallux (HP:0010055)1.20639287
88Nephritis (HP:0000123)1.17841580
89Dental crowding (HP:0000678)1.15873444
90Abnormality of the renal collecting system (HP:0004742)1.15703110
91Type II diabetes mellitus (HP:0005978)1.13341254
92Chronic otitis media (HP:0000389)1.13148052
93Atelectasis (HP:0100750)1.11884454
94Male infertility (HP:0003251)1.11859437
95Goiter (HP:0000853)1.10886534
96Tubular atrophy (HP:0000092)1.10666849
97Abnormality of the astrocytes (HP:0100707)1.10634955
98Astrocytoma (HP:0009592)1.10634955
99Neoplasm of the heart (HP:0100544)1.10181040
100Bell-shaped thorax (HP:0001591)1.09562808

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK126.16675659
2STK165.07063088
3MAPK154.46940500
4TYK24.00518765
5MST43.98171764
6BCR2.94591891
7IRAK12.75054784
8ERBB22.30528043
9MST1R2.08669944
10FRK1.86884656
11LATS11.81841709
12IRAK21.77237192
13IRAK41.74681450
14MAP3K21.73096877
15MUSK1.68575749
16MET1.64424375
17MAP3K71.53035078
18KSR21.41562131
19NME11.38929847
20AURKA1.29809084
21BLK1.24994306
22SGK21.23973017
23RPS6KA21.17064346
24ZAP701.16647552
25STK111.16137112
26ADRBK21.13592752
27IKBKE1.11181283
28TAOK31.10183891
29ERN11.05006237
30CSNK1A1L1.04798155
31CDC42BPA1.03279110
32KDR1.00518583
33TGFBR11.00348258
34RPS6KA60.98549941
35WNK10.97871746
36TRPM70.96526465
37CDK80.96416885
38BMPR1B0.92473364
39PRKCI0.90103450
40MAP3K130.90089580
41STK30.89549671
42MARK20.88542144
43PTK60.87577371
44STK100.86473730
45ERBB40.84875568
46TBK10.81766901
47MAP3K40.80891379
48MAP3K90.79960980
49BRD40.79949844
50TTK0.79170671
51RPS6KC10.78838308
52RPS6KL10.78838308
53SGK2230.77680606
54SGK4940.77680606
55EGFR0.75760457
56CAMK1G0.73460033
57GRK70.72468495
58IKBKB0.71507437
59LRRK20.71473149
60WNK30.71375729
61DAPK20.70209416
62MAPKAPK20.68672766
63GRK10.67610881
64PNCK0.66149675
65WNK40.63746984
66CSK0.61785413
67TLK10.61448046
68STK240.59287215
69NEK90.57812443
70CHUK0.57610086
71SGK30.57119185
72MAP3K30.56261081
73TNK20.55325798
74NEK60.54418200
75PIM10.54307966
76STK380.51213649
77TAOK10.50801898
78EEF2K0.48593372
79FYN0.47344185
80CDK70.45331715
81OXSR10.44639251
82CAMK1D0.42225865
83NUAK10.42153206
84VRK10.40029194
85DMPK0.38866833
86MAP2K10.38190236
87STK390.36696509
88MAPK30.31828158
89PLK10.31726830
90ATM0.30767140
91PTK2B0.27430017
92AKT20.26811927
93MAP3K80.25153897
94NTRK30.24182163
95MAPK10.23927813
96MAP2K70.23708471
97LMTK20.23311594
98FER0.23118236
99CHEK20.23056050
100INSRR0.23033656

Predicted pathways (KEGG)

RankGene SetZ-score
1Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006015.53349672
2Huntingtons disease_Homo sapiens_hsa050163.57812693
3ABC transporters_Homo sapiens_hsa020103.44435329
4Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005333.36770977
5Primary bile acid biosynthesis_Homo sapiens_hsa001202.96312370
6Pentose and glucuronate interconversions_Homo sapiens_hsa000402.93124054
7Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.48839539
8Basal transcription factors_Homo sapiens_hsa030222.18016482
9Linoleic acid metabolism_Homo sapiens_hsa005912.11254189
10Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.08952311
11Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.07150816
12Retinol metabolism_Homo sapiens_hsa008302.04082114
13Chemical carcinogenesis_Homo sapiens_hsa052041.97374985
14Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.94809000
15Steroid hormone biosynthesis_Homo sapiens_hsa001401.93407616
16Hematopoietic cell lineage_Homo sapiens_hsa046401.89215968
17Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.88182826
18Dorso-ventral axis formation_Homo sapiens_hsa043201.80810283
19Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.76198417
20Sphingolipid metabolism_Homo sapiens_hsa006001.57233587
21Caffeine metabolism_Homo sapiens_hsa002321.38802433
22Transcriptional misregulation in cancer_Homo sapiens_hsa052021.34249189
23Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.33118241
24Nitrogen metabolism_Homo sapiens_hsa009101.26481667
25Ovarian steroidogenesis_Homo sapiens_hsa049131.25564457
26Glycosaminoglycan degradation_Homo sapiens_hsa005311.23837635
27Jak-STAT signaling pathway_Homo sapiens_hsa046301.21106810
28Adherens junction_Homo sapiens_hsa045201.18388014
29Tryptophan metabolism_Homo sapiens_hsa003801.14312554
30Circadian rhythm_Homo sapiens_hsa047101.14040495
312-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.13924147
32Histidine metabolism_Homo sapiens_hsa003401.11310009
33Vitamin digestion and absorption_Homo sapiens_hsa049771.10804040
34Asthma_Homo sapiens_hsa053101.09553229
35Antigen processing and presentation_Homo sapiens_hsa046121.02928826
36alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.00074318
37ErbB signaling pathway_Homo sapiens_hsa040120.90223437
38Cell cycle_Homo sapiens_hsa041100.89323450
39Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.85212965
40Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.83693719
41Drug metabolism - other enzymes_Homo sapiens_hsa009830.77038315
42Nicotine addiction_Homo sapiens_hsa050330.75292559
43Autoimmune thyroid disease_Homo sapiens_hsa053200.73897945
44Fructose and mannose metabolism_Homo sapiens_hsa000510.71273196
45Notch signaling pathway_Homo sapiens_hsa043300.70126417
46Peroxisome_Homo sapiens_hsa041460.69889430
47Allograft rejection_Homo sapiens_hsa053300.68795864
48Small cell lung cancer_Homo sapiens_hsa052220.65765500
49Inositol phosphate metabolism_Homo sapiens_hsa005620.65149731
50Taste transduction_Homo sapiens_hsa047420.64330214
51Oocyte meiosis_Homo sapiens_hsa041140.64161118
52Pentose phosphate pathway_Homo sapiens_hsa000300.63717621
53Phototransduction_Homo sapiens_hsa047440.63167463
54Arachidonic acid metabolism_Homo sapiens_hsa005900.57748655
55Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.57409930
56Olfactory transduction_Homo sapiens_hsa047400.56806222
57Graft-versus-host disease_Homo sapiens_hsa053320.55519368
58Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.54645636
59Regulation of autophagy_Homo sapiens_hsa041400.54357743
60Thyroid hormone signaling pathway_Homo sapiens_hsa049190.52492735
61Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.52333869
62Influenza A_Homo sapiens_hsa051640.51303549
63beta-Alanine metabolism_Homo sapiens_hsa004100.49115799
64Viral myocarditis_Homo sapiens_hsa054160.48736700
65Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.46798810
66Tight junction_Homo sapiens_hsa045300.46510068
67Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.45310173
68Lysine degradation_Homo sapiens_hsa003100.44738593
69Amoebiasis_Homo sapiens_hsa051460.42834631
70Herpes simplex infection_Homo sapiens_hsa051680.42487342
71Primary immunodeficiency_Homo sapiens_hsa053400.41149711
72Hepatitis C_Homo sapiens_hsa051600.40720278
73Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.40313526
74Basal cell carcinoma_Homo sapiens_hsa052170.38536061
75TNF signaling pathway_Homo sapiens_hsa046680.38108846
76p53 signaling pathway_Homo sapiens_hsa041150.37324068
77Intestinal immune network for IgA production_Homo sapiens_hsa046720.36463499
78NOD-like receptor signaling pathway_Homo sapiens_hsa046210.35486792
79HTLV-I infection_Homo sapiens_hsa051660.34994084
80ECM-receptor interaction_Homo sapiens_hsa045120.34976627
81Salivary secretion_Homo sapiens_hsa049700.33129343
82Prolactin signaling pathway_Homo sapiens_hsa049170.31683526
83Collecting duct acid secretion_Homo sapiens_hsa049660.30875473
84Ether lipid metabolism_Homo sapiens_hsa005650.30557489
85Sphingolipid signaling pathway_Homo sapiens_hsa040710.29136269
86Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.28558368
87Ras signaling pathway_Homo sapiens_hsa040140.27963744
88Staphylococcus aureus infection_Homo sapiens_hsa051500.27724206
89Calcium signaling pathway_Homo sapiens_hsa040200.27071283
90Tuberculosis_Homo sapiens_hsa051520.26905131
91Phosphatidylinositol signaling system_Homo sapiens_hsa040700.26888146
92Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.26358475
93Amphetamine addiction_Homo sapiens_hsa050310.23575059
94Hedgehog signaling pathway_Homo sapiens_hsa043400.22588930
95Starch and sucrose metabolism_Homo sapiens_hsa005000.22065402
96Bile secretion_Homo sapiens_hsa049760.21949871
97Hippo signaling pathway_Homo sapiens_hsa043900.21773376
98Type I diabetes mellitus_Homo sapiens_hsa049400.21596112
99Sulfur metabolism_Homo sapiens_hsa009200.21364966
100Vascular smooth muscle contraction_Homo sapiens_hsa042700.21124397

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