

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of T-helper 2 cell differentiation (GO:0045628) | 9.87484315 |
| 2 | activation of protein kinase A activity (GO:0034199) | 9.81800178 |
| 3 | regulation of T-helper 1 cell differentiation (GO:0045625) | 9.62816802 |
| 4 | negative regulation of type 2 immune response (GO:0002829) | 9.48127581 |
| 5 | seminiferous tubule development (GO:0072520) | 9.40293130 |
| 6 | positive regulation of RNA splicing (GO:0033120) | 9.08820021 |
| 7 | cAMP biosynthetic process (GO:0006171) | 8.84345797 |
| 8 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 8.64700317 |
| 9 | detection of chemical stimulus involved in sensory perception (GO:0050907) | 8.28530898 |
| 10 | negative regulation of alpha-beta T cell differentiation (GO:0046639) | 7.89297140 |
| 11 | enteric nervous system development (GO:0048484) | 7.50570719 |
| 12 | dendritic spine morphogenesis (GO:0060997) | 7.24094870 |
| 13 | regulation of protein sumoylation (GO:0033233) | 6.95465492 |
| 14 | synaptic transmission, dopaminergic (GO:0001963) | 6.65693992 |
| 15 | positive regulation of mitochondrial fission (GO:0090141) | 6.51035223 |
| 16 | righting reflex (GO:0060013) | 6.38436747 |
| 17 | heterotypic cell-cell adhesion (GO:0034113) | 6.19793312 |
| 18 | endothelial cell differentiation (GO:0045446) | 6.15809297 |
| 19 | arachidonic acid secretion (GO:0050482) | 6.12292025 |
| 20 | icosanoid secretion (GO:0032309) | 6.12292025 |
| 21 | positive regulation of T-helper 1 type immune response (GO:0002827) | 5.99312460 |
| 22 | detection of chemical stimulus (GO:0009593) | 5.95541170 |
| 23 | hepatocyte apoptotic process (GO:0097284) | 5.71633093 |
| 24 | positive regulation of T-helper cell differentiation (GO:0045624) | 5.65485084 |
| 25 | drug transmembrane transport (GO:0006855) | 5.31929528 |
| 26 | phosphatidylinositol acyl-chain remodeling (GO:0036149) | 5.09691247 |
| 27 | fatty acid derivative transport (GO:1901571) | 5.08071935 |
| 28 | icosanoid transport (GO:0071715) | 5.08071935 |
| 29 | phosphatidylserine acyl-chain remodeling (GO:0036150) | 4.85470709 |
| 30 | neuronal ion channel clustering (GO:0045161) | 4.81620469 |
| 31 | nephron tubule morphogenesis (GO:0072078) | 4.78588249 |
| 32 | nephron epithelium morphogenesis (GO:0072088) | 4.78588249 |
| 33 | negative regulation of actin filament bundle assembly (GO:0032232) | 4.72065783 |
| 34 | neural tube formation (GO:0001841) | 4.68589703 |
| 35 | regulation of mitochondrial fission (GO:0090140) | 4.67557107 |
| 36 | phosphatidylglycerol acyl-chain remodeling (GO:0036148) | 4.66524496 |
| 37 | hyaluronan catabolic process (GO:0030214) | 4.60271956 |
| 38 | cilium or flagellum-dependent cell motility (GO:0001539) | 4.59825562 |
| 39 | chemosensory behavior (GO:0007635) | 4.59043284 |
| 40 | negative regulation of alpha-beta T cell activation (GO:0046636) | 4.52591976 |
| 41 | vocalization behavior (GO:0071625) | 4.48133597 |
| 42 | embryonic digestive tract morphogenesis (GO:0048557) | 4.47475124 |
| 43 | cyclic purine nucleotide metabolic process (GO:0052652) | 4.38728236 |
| 44 | cyclic nucleotide biosynthetic process (GO:0009190) | 4.34950377 |
| 45 | positive regulation of membrane potential (GO:0045838) | 4.30062686 |
| 46 | positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372) | 4.27193830 |
| 47 | regulation of T-helper 1 type immune response (GO:0002825) | 4.26363735 |
| 48 | dendritic spine organization (GO:0097061) | 4.22634522 |
| 49 | retina layer formation (GO:0010842) | 4.21767787 |
| 50 | cAMP metabolic process (GO:0046058) | 4.09267031 |
| 51 | regulation of T-helper cell differentiation (GO:0045622) | 4.08650348 |
| 52 | regulation of cAMP-mediated signaling (GO:0043949) | 4.02690797 |
| 53 | cellular response to glucagon stimulus (GO:0071377) | 4.02367373 |
| 54 | regulation of type 2 immune response (GO:0002828) | 3.99544474 |
| 55 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 3.99248945 |
| 56 | water transport (GO:0006833) | 3.98981763 |
| 57 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.94261634 |
| 58 | cellular zinc ion homeostasis (GO:0006882) | 3.92650157 |
| 59 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 3.91237940 |
| 60 | ATP hydrolysis coupled proton transport (GO:0015991) | 3.91237940 |
| 61 | drug transport (GO:0015893) | 3.82935847 |
| 62 | response to dietary excess (GO:0002021) | 3.82058919 |
| 63 | protein localization to synapse (GO:0035418) | 3.80103074 |
| 64 | positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516) | 3.75759232 |
| 65 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 3.69002105 |
| 66 | positive regulation of protein targeting to membrane (GO:0090314) | 3.67711108 |
| 67 | leukotriene biosynthetic process (GO:0019370) | 3.64846198 |
| 68 | negative regulation of T cell differentiation (GO:0045581) | 3.62673727 |
| 69 | fluid transport (GO:0042044) | 3.54462185 |
| 70 | mitochondrial fusion (GO:0008053) | 3.53133476 |
| 71 | left/right axis specification (GO:0070986) | 3.52251411 |
| 72 | cellular response to ATP (GO:0071318) | 3.46477556 |
| 73 | monoamine transport (GO:0015844) | 3.43457332 |
| 74 | renal tubule morphogenesis (GO:0061333) | 3.41223975 |
| 75 | phosphatidylethanolamine acyl-chain remodeling (GO:0036152) | 3.37205212 |
| 76 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 3.30429626 |
| 77 | neurofilament cytoskeleton organization (GO:0060052) | 3.23732478 |
| 78 | pre-miRNA processing (GO:0031054) | 3.23255128 |
| 79 | sequestering of metal ion (GO:0051238) | 3.22837016 |
| 80 | regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370) | 3.20045116 |
| 81 | sulfur amino acid catabolic process (GO:0000098) | 3.20042584 |
| 82 | positive regulation of alpha-beta T cell differentiation (GO:0046638) | 3.18187848 |
| 83 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors (GO:1902043) | 3.17589555 |
| 84 | negative regulation of homotypic cell-cell adhesion (GO:0034111) | 3.14537378 |
| 85 | positive regulation of dendritic spine development (GO:0060999) | 3.14492513 |
| 86 | adenylate cyclase-activating G-protein coupled receptor signaling pathway (GO:0007189) | 3.13143280 |
| 87 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 3.12298455 |
| 88 | response to auditory stimulus (GO:0010996) | 3.07468136 |
| 89 | axonemal dynein complex assembly (GO:0070286) | 3.06998822 |
| 90 | prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:006052 | 3.06635438 |
| 91 | response to glucagon (GO:0033762) | 3.04105659 |
| 92 | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway (GO:0007193) | 3.03036100 |
| 93 | zinc ion homeostasis (GO:0055069) | 3.00203839 |
| 94 | single fertilization (GO:0007338) | 2.95300292 |
| 95 | tooth mineralization (GO:0034505) | 13.9853290 |
| 96 | detection of chemical stimulus involved in sensory perception of smell (GO:0050911) | 13.3449204 |
| 97 | positive regulation of protein sumoylation (GO:0033235) | 11.1965079 |
| 98 | negative regulation of T-helper cell differentiation (GO:0045623) | 10.7318719 |
| 99 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 10.7318719 |
| 100 | protein K11-linked deubiquitination (GO:0035871) | 10.1815164 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 9.63894642 |
| 2 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 6.24438547 |
| 3 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 5.21220918 |
| 4 | AR_21572438_ChIP-Seq_LNCaP_Human | 4.50383820 |
| 5 | IGF1R_20145208_ChIP-Seq_DFB_Human | 4.37780932 |
| 6 | VDR_22108803_ChIP-Seq_LS180_Human | 3.99144012 |
| 7 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 3.10834874 |
| 8 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.90105953 |
| 9 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.90105953 |
| 10 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.87731645 |
| 11 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.86780755 |
| 12 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.86632258 |
| 13 | GATA1_19941826_ChIP-Seq_K562_Human | 1.84560730 |
| 14 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.82399488 |
| 15 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.76681393 |
| 16 | TP53_16413492_ChIP-PET_HCT116_Human | 1.76333894 |
| 17 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.68459623 |
| 18 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.67823988 |
| 19 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.56547523 |
| 20 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.53751818 |
| 21 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.52629313 |
| 22 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.51539927 |
| 23 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.45087510 |
| 24 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.44703258 |
| 25 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.43820787 |
| 26 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.43193367 |
| 27 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.40310344 |
| 28 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.40290986 |
| 29 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.37324156 |
| 30 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.35856789 |
| 31 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.35194819 |
| 32 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.33739883 |
| 33 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.30684495 |
| 34 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.26121934 |
| 35 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.21222682 |
| 36 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.21216209 |
| 37 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.20658024 |
| 38 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.20467541 |
| 39 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.19855160 |
| 40 | RXR_22108803_ChIP-Seq_LS180_Human | 1.19678316 |
| 41 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.19582895 |
| 42 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.19360125 |
| 43 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.14545034 |
| 44 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.14489702 |
| 45 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.14333490 |
| 46 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.14331574 |
| 47 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.14119395 |
| 48 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.13254423 |
| 49 | HNFA_21074721_ChIP-Seq_CACO-2_Human | 1.12529644 |
| 50 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.10313542 |
| 51 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.09757543 |
| 52 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.08803519 |
| 53 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.08243876 |
| 54 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.06922628 |
| 55 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.06235156 |
| 56 | TBL1_22424771_ChIP-Seq_293T_Human | 1.05757964 |
| 57 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.05224421 |
| 58 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 1.04526671 |
| 59 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 1.03454885 |
| 60 | CJUN_26792858_Chip-Seq_BT549_Human | 1.02999235 |
| 61 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.01070600 |
| 62 | EZH2_22144423_ChIP-Seq_EOC_Human | 0.99622561 |
| 63 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.99043287 |
| 64 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.98644593 |
| 65 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.98464154 |
| 66 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 0.97458833 |
| 67 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 0.96347428 |
| 68 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 0.96143030 |
| 69 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 0.96143030 |
| 70 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 0.96041100 |
| 71 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.94008054 |
| 72 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 0.92757583 |
| 73 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.92290946 |
| 74 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.92290946 |
| 75 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 0.92125327 |
| 76 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 0.89778868 |
| 77 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.88738585 |
| 78 | STAT3_23295773_ChIP-Seq_U87_Human | 0.87697657 |
| 79 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.87523959 |
| 80 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.87079034 |
| 81 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 0.86604156 |
| 82 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.86079541 |
| 83 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 0.85727474 |
| 84 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.84973130 |
| 85 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.83868405 |
| 86 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.83257830 |
| 87 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.82633873 |
| 88 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 0.81885009 |
| 89 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.80774355 |
| 90 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.80588082 |
| 91 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.80534439 |
| 92 | ETV1_20927104_ChIP-Seq_GIST48_Human | 0.80391372 |
| 93 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.80176706 |
| 94 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 0.80157549 |
| 95 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.79909327 |
| 96 | TP53_18474530_ChIP-ChIP_U2OS_Human | 0.79198204 |
| 97 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.78485102 |
| 98 | REST_21632747_ChIP-Seq_MESCs_Mouse | 0.78050894 |
| 99 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 0.78033385 |
| 100 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.77620071 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008961_abnormal_basal_metabolism | 9.11496414 |
| 2 | MP0004130_abnormal_muscle_cell | 4.56840443 |
| 3 | MP0003252_abnormal_bile_duct | 3.79546495 |
| 4 | MP0004264_abnormal_extraembryonic_tissu | 3.69731757 |
| 5 | MP0002928_abnormal_bile_duct | 3.50226101 |
| 6 | MP0004133_heterotaxia | 2.52940595 |
| 7 | MP0006072_abnormal_retinal_apoptosis | 2.43280730 |
| 8 | MP0001270_distended_abdomen | 2.16170745 |
| 9 | MP0005448_abnormal_energy_balance | 2.09249177 |
| 10 | MP0004272_abnormal_basement_membrane | 2.05504807 |
| 11 | MP0005084_abnormal_gallbladder_morpholo | 12.9708096 |
| 12 | MP0005408_hypopigmentation | 1.95470426 |
| 13 | MP0002751_abnormal_autonomic_nervous | 1.82547948 |
| 14 | MP0003329_amyloid_beta_deposits | 1.75633918 |
| 15 | MP0003943_abnormal_hepatobiliary_system | 1.69192790 |
| 16 | MP0005379_endocrine/exocrine_gland_phen | 1.51054402 |
| 17 | MP0005165_increased_susceptibility_to | 1.50128812 |
| 18 | MP0003718_maternal_effect | 1.41177041 |
| 19 | MP0009764_decreased_sensitivity_to | 1.40166240 |
| 20 | MP0003638_abnormal_response/metabolism_ | 1.32424927 |
| 21 | MP0005220_abnormal_exocrine_pancreas | 1.29891117 |
| 22 | MP0003878_abnormal_ear_physiology | 1.22112542 |
| 23 | MP0005377_hearing/vestibular/ear_phenot | 1.22112542 |
| 24 | MP0005410_abnormal_fertilization | 1.19020544 |
| 25 | MP0001529_abnormal_vocalization | 1.11260880 |
| 26 | MP0002405_respiratory_system_inflammati | 1.07695936 |
| 27 | MP0000604_amyloidosis | 1.07489641 |
| 28 | MP0001958_emphysema | 1.06818620 |
| 29 | MP0000465_gastrointestinal_hemorrhage | 1.06108548 |
| 30 | MP0000470_abnormal_stomach_morphology | 1.06086540 |
| 31 | MP0005646_abnormal_pituitary_gland | 0.96012392 |
| 32 | MP0001851_eye_inflammation | 0.93513746 |
| 33 | MP0001905_abnormal_dopamine_level | 0.92562036 |
| 34 | MP0002098_abnormal_vibrissa_morphology | 0.90942921 |
| 35 | MP0002572_abnormal_emotion/affect_behav | 0.90167805 |
| 36 | MP0001944_abnormal_pancreas_morphology | 0.87294858 |
| 37 | MP0008569_lethality_at_weaning | 0.85645502 |
| 38 | MP0005164_abnormal_response_to | 0.84220232 |
| 39 | MP0008469_abnormal_protein_level | 0.81275968 |
| 40 | MP0001800_abnormal_humoral_immune | 0.77706817 |
| 41 | MP0001533_abnormal_skeleton_physiology | 0.68333070 |
| 42 | MP0000371_diluted_coat_color | 0.65876815 |
| 43 | MP0010234_abnormal_vibrissa_follicle | 0.65232610 |
| 44 | MP0003866_abnormal_defecation | 0.64417667 |
| 45 | MP0000703_abnormal_thymus_morphology | 0.64408797 |
| 46 | MP0002136_abnormal_kidney_physiology | 0.63891099 |
| 47 | MP0008875_abnormal_xenobiotic_pharmacok | 0.63726808 |
| 48 | MP0005253_abnormal_eye_physiology | 0.63461652 |
| 49 | MP0005387_immune_system_phenotype | 0.63050825 |
| 50 | MP0001790_abnormal_immune_system | 0.63050825 |
| 51 | MP0000609_abnormal_liver_physiology | 0.62385517 |
| 52 | MP0004947_skin_inflammation | 0.61661191 |
| 53 | MP0001879_abnormal_lymphatic_vessel | 0.61193735 |
| 54 | MP0001501_abnormal_sleep_pattern | 0.60477246 |
| 55 | MP0002693_abnormal_pancreas_physiology | 0.57722174 |
| 56 | MP0001915_intracranial_hemorrhage | 0.57539336 |
| 57 | MP0002909_abnormal_adrenal_gland | 0.56925633 |
| 58 | MP0005551_abnormal_eye_electrophysiolog | 0.55486004 |
| 59 | MP0002998_abnormal_bone_remodeling | 0.53321418 |
| 60 | MP0004019_abnormal_vitamin_homeostasis | 0.53124755 |
| 61 | MP0001845_abnormal_inflammatory_respons | 0.53107480 |
| 62 | MP0009053_abnormal_anal_canal | 0.52237644 |
| 63 | MP0002078_abnormal_glucose_homeostasis | 0.50921557 |
| 64 | MP0003953_abnormal_hormone_level | 0.50402589 |
| 65 | MP0002722_abnormal_immune_system | 0.50120754 |
| 66 | MP0002735_abnormal_chemical_nociception | 0.49310510 |
| 67 | MP0003724_increased_susceptibility_to | 0.48461011 |
| 68 | MP0003121_genomic_imprinting | 0.46962805 |
| 69 | MP0002419_abnormal_innate_immunity | 0.46730879 |
| 70 | MP0004484_altered_response_of | 0.44817338 |
| 71 | MP0000249_abnormal_blood_vessel | 0.43511836 |
| 72 | MP0004885_abnormal_endolymph | 0.42610457 |
| 73 | MP0009642_abnormal_blood_homeostasis | 0.41094918 |
| 74 | MP0010368_abnormal_lymphatic_system | 0.40130135 |
| 75 | MP0000477_abnormal_intestine_morphology | 0.38540130 |
| 76 | MP0008004_abnormal_stomach_pH | 0.38449550 |
| 77 | MP0005423_abnormal_somatic_nervous | 0.37154798 |
| 78 | MP0005334_abnormal_fat_pad | 0.36990839 |
| 79 | MP0002429_abnormal_blood_cell | 0.36811400 |
| 80 | MP0002723_abnormal_immune_serum | 0.36713391 |
| 81 | MP0002420_abnormal_adaptive_immunity | 0.36615312 |
| 82 | MP0003195_calcinosis | 0.35835023 |
| 83 | MP0002452_abnormal_antigen_presenting | 0.35675744 |
| 84 | MP0002161_abnormal_fertility/fecundity | 0.35370041 |
| 85 | MP0001819_abnormal_immune_cell | 0.35279249 |
| 86 | MP0009785_altered_susceptibility_to | 0.34992220 |
| 87 | MP0002822_catalepsy | 0.34403678 |
| 88 | MP0000598_abnormal_liver_morphology | 0.34041076 |
| 89 | MP0005390_skeleton_phenotype | 0.33458165 |
| 90 | MP0000716_abnormal_immune_system | 0.32452923 |
| 91 | MP0002398_abnormal_bone_marrow | 0.32287625 |
| 92 | MP0005395_other_phenotype | 0.31419846 |
| 93 | MP0003698_abnormal_male_reproductive | 0.30578691 |
| 94 | MP0009931_abnormal_skin_appearance | 0.30476791 |
| 95 | MP0002229_neurodegeneration | 0.29437091 |
| 96 | MP0000920_abnormal_myelination | 0.29310195 |
| 97 | MP0005000_abnormal_immune_tolerance | 0.28656811 |
| 98 | MP0002882_abnormal_neuron_morphology | 0.28074575 |
| 99 | MP0003879_abnormal_hair_cell | 0.27929045 |
| 100 | MP0000689_abnormal_spleen_morphology | 0.27341844 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of calcium-phosphate metabolism (HP:0100530) | 9.49697671 |
| 2 | Abnormality of dental color (HP:0011073) | 8.39136375 |
| 3 | Polyuria (HP:0000103) | 7.99759760 |
| 4 | Abnormality of renal resorption (HP:0011038) | 7.77961010 |
| 5 | Osteomalacia (HP:0002749) | 7.45378533 |
| 6 | Abnormal urine output (HP:0012590) | 6.94247540 |
| 7 | Abnormality of the dental pulp (HP:0006479) | 6.87349278 |
| 8 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 6.60995189 |
| 9 | Abnormality of renal excretion (HP:0011036) | 6.04318765 |
| 10 | Round ear (HP:0100830) | 4.93886993 |
| 11 | Chronic bronchitis (HP:0004469) | 4.61694060 |
| 12 | Volvulus (HP:0002580) | 4.09487665 |
| 13 | Autoimmune thrombocytopenia (HP:0001973) | 4.09198306 |
| 14 | IgM deficiency (HP:0002850) | 3.97779499 |
| 15 | Abnormality of midbrain morphology (HP:0002418) | 3.81386966 |
| 16 | Molar tooth sign on MRI (HP:0002419) | 3.81386966 |
| 17 | Lip pit (HP:0100267) | 3.70062479 |
| 18 | Toxemia of pregnancy (HP:0100603) | 3.68134593 |
| 19 | Esophageal varix (HP:0002040) | 3.66968442 |
| 20 | Nephrocalcinosis (HP:0000121) | 3.62245160 |
| 21 | Rhinitis (HP:0012384) | 3.56096970 |
| 22 | Abnormal respiratory motile cilium physiology (HP:0012261) | 3.44674920 |
| 23 | Sparse lateral eyebrow (HP:0005338) | 3.20337992 |
| 24 | Nephronophthisis (HP:0000090) | 3.15708442 |
| 25 | Large earlobe (HP:0009748) | 3.06603528 |
| 26 | Lipoatrophy (HP:0100578) | 3.04577216 |
| 27 | Hypoparathyroidism (HP:0000829) | 3.02317315 |
| 28 | Hyperphosphaturia (HP:0003109) | 3.01905794 |
| 29 | Tachypnea (HP:0002789) | 2.99465461 |
| 30 | Depressed nasal tip (HP:0000437) | 2.99389168 |
| 31 | Intestinal fistula (HP:0100819) | 2.96000667 |
| 32 | Thick eyebrow (HP:0000574) | 2.82937015 |
| 33 | Drooling (HP:0002307) | 2.74468383 |
| 34 | Abnormality of the renal medulla (HP:0100957) | 2.70294976 |
| 35 | Excessive salivation (HP:0003781) | 2.62671124 |
| 36 | Panhypogammaglobulinemia (HP:0003139) | 2.60328060 |
| 37 | Abnormal urine phosphate concentration (HP:0012599) | 2.53826485 |
| 38 | Inability to walk (HP:0002540) | 2.47932608 |
| 39 | Personality changes (HP:0000751) | 2.41888285 |
| 40 | Hepatitis (HP:0012115) | 2.30944617 |
| 41 | Nephropathy (HP:0000112) | 2.29382894 |
| 42 | Abnormality of urine glucose concentration (HP:0011016) | 2.28553544 |
| 43 | Glycosuria (HP:0003076) | 2.28553544 |
| 44 | Petechiae (HP:0000967) | 2.25762261 |
| 45 | Gingival overgrowth (HP:0000212) | 2.25339399 |
| 46 | Hypercalciuria (HP:0002150) | 2.24684072 |
| 47 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.24293732 |
| 48 | Ureteral stenosis (HP:0000071) | 2.21976366 |
| 49 | Stage 5 chronic kidney disease (HP:0003774) | 2.19584959 |
| 50 | Preauricular pit (HP:0004467) | 2.19270102 |
| 51 | Periauricular skin pits (HP:0100277) | 2.19270102 |
| 52 | Abnormality of transition element cation homeostasis (HP:0011030) | 2.16152986 |
| 53 | Short 5th finger (HP:0009237) | 2.15213405 |
| 54 | Dilated cardiomyopathy (HP:0001644) | 2.14763315 |
| 55 | Bronchitis (HP:0012387) | 2.12036756 |
| 56 | Anal stenosis (HP:0002025) | 2.09427593 |
| 57 | Sudden cardiac death (HP:0001645) | 2.08159321 |
| 58 | Aplasia/Hypoplasia of the 5th finger (HP:0006262) | 2.05134284 |
| 59 | Ureteral obstruction (HP:0006000) | 2.00132935 |
| 60 | Overgrowth (HP:0001548) | 11.3818619 |
| 61 | Amelogenesis imperfecta (HP:0000705) | 11.0498315 |
| 62 | Chondrocalcinosis (HP:0000934) | 1.99672179 |
| 63 | Chronic mucocutaneous candidiasis (HP:0002728) | 1.96008158 |
| 64 | Recurrent cutaneous fungal infections (HP:0011370) | 1.96008158 |
| 65 | Abnormality of the fingertips (HP:0001211) | 1.94884004 |
| 66 | Abnormality of Sharpey fibers (HP:0100685) | 1.94139369 |
| 67 | Recurrent otitis media (HP:0000403) | 1.92774429 |
| 68 | Colitis (HP:0002583) | 1.92527432 |
| 69 | Striae distensae (HP:0001065) | 1.87760627 |
| 70 | Delayed eruption of teeth (HP:0000684) | 1.82930906 |
| 71 | Abnormality of salivation (HP:0100755) | 1.79716546 |
| 72 | Chorioretinal coloboma (HP:0000567) | 1.76559222 |
| 73 | Agammaglobulinemia (HP:0004432) | 1.73548055 |
| 74 | Ectopic kidney (HP:0000086) | 1.70124808 |
| 75 | Hypotrichosis (HP:0001006) | 1.69613694 |
| 76 | Renal tubular dysfunction (HP:0000124) | 1.69593559 |
| 77 | Decreased muscle mass (HP:0003199) | 1.68778147 |
| 78 | Prominent supraorbital ridges (HP:0000336) | 1.63760481 |
| 79 | Bronchiectasis (HP:0002110) | 1.61182935 |
| 80 | Facial shape deformation (HP:0011334) | 1.60503556 |
| 81 | Potter facies (HP:0002009) | 1.60503556 |
| 82 | Truncal ataxia (HP:0002078) | 1.55508707 |
| 83 | Polyneuropathy (HP:0001271) | 1.55401316 |
| 84 | Limited elbow extension (HP:0001377) | 1.51266995 |
| 85 | Small hand (HP:0200055) | 1.49499522 |
| 86 | Preauricular skin tag (HP:0000384) | 1.48762754 |
| 87 | Skin pits (HP:0100276) | 1.47946897 |
| 88 | Congenital sensorineural hearing impairment (HP:0008527) | 1.45478459 |
| 89 | Attenuation of retinal blood vessels (HP:0007843) | 1.42751153 |
| 90 | Aplasia/Hypoplasia of the earlobes (HP:0009906) | 1.41809079 |
| 91 | Osteoarthritis (HP:0002758) | 1.40243372 |
| 92 | Ectropion (HP:0000656) | 1.38747962 |
| 93 | Oculomotor apraxia (HP:0000657) | 1.38040482 |
| 94 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.36166822 |
| 95 | Palmoplantar keratoderma (HP:0000982) | 1.36072234 |
| 96 | Hypokalemic alkalosis (HP:0001949) | 1.35386500 |
| 97 | Prenatal maternal abnormality (HP:0002686) | 1.34784061 |
| 98 | Torticollis (HP:0000473) | 1.34334906 |
| 99 | Abnormality of sodium homeostasis (HP:0010931) | 1.29533971 |
| 100 | Blepharitis (HP:0000498) | 1.29507623 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K1 | 5.50314729 |
| 2 | BLK | 4.01107515 |
| 3 | STK3 | 3.71615940 |
| 4 | RIPK4 | 3.22547495 |
| 5 | CDC42BPA | 2.06827202 |
| 6 | BMPR2 | 2.03428856 |
| 7 | NTRK2 | 13.3256167 |
| 8 | MAPK15 | 1.98251288 |
| 9 | TIE1 | 1.92220787 |
| 10 | TSSK6 | 1.91009700 |
| 11 | HIPK2 | 1.02841390 |
| 12 | INSRR | 0.98565259 |
| 13 | STK39 | 0.95897326 |
| 14 | PRKCQ | 0.93885067 |
| 15 | WNK4 | 0.88500868 |
| 16 | MAP4K2 | 0.82836331 |
| 17 | FGFR1 | 0.80007639 |
| 18 | PLK4 | 0.78299756 |
| 19 | GRK6 | 0.75607913 |
| 20 | DDR2 | 0.70612403 |
| 21 | PRKD3 | 0.67591455 |
| 22 | MAP3K14 | 0.65929169 |
| 23 | SYK | 0.64627064 |
| 24 | ROCK2 | 0.63155490 |
| 25 | MAP2K2 | 0.62291939 |
| 26 | OBSCN | 0.61290942 |
| 27 | SRC | 0.59203190 |
| 28 | TXK | 0.58774847 |
| 29 | MUSK | 0.55346085 |
| 30 | ZAK | 0.52420296 |
| 31 | ADRBK2 | 0.50088465 |
| 32 | OXSR1 | 0.48511963 |
| 33 | ROCK1 | 0.47387704 |
| 34 | MATK | 0.47099326 |
| 35 | GRK1 | 0.46909283 |
| 36 | PRKAA1 | 0.45348631 |
| 37 | TLK1 | 0.43538969 |
| 38 | TEC | 0.43083639 |
| 39 | PRKACG | 0.39538528 |
| 40 | GRK7 | 0.39002467 |
| 41 | PRKACB | 0.38946649 |
| 42 | CAMK2A | 0.38146025 |
| 43 | ABL1 | 0.37242471 |
| 44 | DAPK2 | 0.34142237 |
| 45 | PRKACA | 0.33974292 |
| 46 | EPHB2 | 0.33635230 |
| 47 | WNK3 | 0.31077924 |
| 48 | KIT | 0.31058036 |
| 49 | PIK3CG | 0.30071057 |
| 50 | PIM1 | 0.28918856 |
| 51 | MST1R | 0.28573629 |
| 52 | MAP3K3 | 0.28564605 |
| 53 | ERBB4 | 0.26661854 |
| 54 | MAPK14 | 0.24457948 |
| 55 | TAOK3 | 0.23841699 |
| 56 | GSK3B | 0.22699171 |
| 57 | MAPK7 | 0.22630825 |
| 58 | PRKCA | 0.22503581 |
| 59 | CDK3 | 0.22469595 |
| 60 | CAMK2G | 0.22117479 |
| 61 | CAMKK1 | 0.21911497 |
| 62 | RPS6KA3 | 0.20686243 |
| 63 | PKN1 | 0.20197368 |
| 64 | PNCK | 0.20176306 |
| 65 | ITK | 0.20004787 |
| 66 | KDR | 0.19335165 |
| 67 | LYN | 0.18791921 |
| 68 | PLK1 | 0.18363145 |
| 69 | BTK | 0.17674646 |
| 70 | EGFR | 0.17085792 |
| 71 | PRKCD | 0.16596136 |
| 72 | RPS6KA5 | 0.16043720 |
| 73 | PRKCB | 0.15892744 |
| 74 | FYN | 0.15827013 |
| 75 | PIK3CA | 0.15682847 |
| 76 | PRKCG | 0.15636547 |
| 77 | MAPK9 | 0.15494784 |
| 78 | EPHA4 | 0.15067594 |
| 79 | CDK1 | 0.14618720 |
| 80 | CAMK2D | 0.14452549 |
| 81 | PRKG1 | 0.14412554 |
| 82 | MAP3K2 | 0.14286976 |
| 83 | BCKDK | 0.13612817 |
| 84 | PDK2 | 0.12476301 |
| 85 | PINK1 | 0.11794493 |
| 86 | VRK1 | 0.11726730 |
| 87 | AKT1 | 0.11532690 |
| 88 | LCK | 0.11143591 |
| 89 | EPHA2 | 0.10756897 |
| 90 | TESK1 | 0.10056828 |
| 91 | CSNK1A1 | 0.10035778 |
| 92 | CAMK2B | 0.10020682 |
| 93 | MAP2K6 | 0.09579532 |
| 94 | IGF1R | 0.08557172 |
| 95 | ADRBK1 | 0.08373100 |
| 96 | PIM2 | 0.07583238 |
| 97 | LMTK2 | 0.06526013 |
| 98 | PAK2 | 0.06364752 |
| 99 | MAPK12 | 0.06328446 |
| 100 | STK38L | 0.05983499 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Olfactory transduction_Homo sapiens_hsa04740 | 5.37042611 |
| 2 | Sulfur relay system_Homo sapiens_hsa04122 | 3.44265002 |
| 3 | Sulfur metabolism_Homo sapiens_hsa00920 | 3.29497636 |
| 4 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 3.27215440 |
| 5 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 3.02805912 |
| 6 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.91119006 |
| 7 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.72880939 |
| 8 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 2.59184614 |
| 9 | Bile secretion_Homo sapiens_hsa04976 | 2.57876089 |
| 10 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.26486700 |
| 11 | Gastric acid secretion_Homo sapiens_hsa04971 | 2.18628507 |
| 12 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 2.18097668 |
| 13 | Pancreatic secretion_Homo sapiens_hsa04972 | 2.14270317 |
| 14 | Salivary secretion_Homo sapiens_hsa04970 | 2.13795088 |
| 15 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 2.12961351 |
| 16 | Fat digestion and absorption_Homo sapiens_hsa04975 | 2.00546434 |
| 17 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.99691636 |
| 18 | Circadian entrainment_Homo sapiens_hsa04713 | 1.92495021 |
| 19 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.86274231 |
| 20 | Cocaine addiction_Homo sapiens_hsa05030 | 1.83648029 |
| 21 | Insulin secretion_Homo sapiens_hsa04911 | 1.83025418 |
| 22 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.78303021 |
| 23 | Morphine addiction_Homo sapiens_hsa05032 | 1.74325191 |
| 24 | Taste transduction_Homo sapiens_hsa04742 | 1.72159365 |
| 25 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.70422001 |
| 26 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.69458980 |
| 27 | GABAergic synapse_Homo sapiens_hsa04727 | 1.68477723 |
| 28 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.56368218 |
| 29 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.54875964 |
| 30 | Gap junction_Homo sapiens_hsa04540 | 1.53642218 |
| 31 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.50593862 |
| 32 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 1.49959419 |
| 33 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.43329895 |
| 34 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.40502572 |
| 35 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.38331845 |
| 36 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.37958024 |
| 37 | Circadian rhythm_Homo sapiens_hsa04710 | 1.35376369 |
| 38 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.29894003 |
| 39 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.27095142 |
| 40 | Melanogenesis_Homo sapiens_hsa04916 | 1.26564391 |
| 41 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.19649377 |
| 42 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.18087058 |
| 43 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.12721653 |
| 44 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.11234441 |
| 45 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.10927499 |
| 46 | Platelet activation_Homo sapiens_hsa04611 | 1.06368257 |
| 47 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.06219867 |
| 48 | Prion diseases_Homo sapiens_hsa05020 | 0.82274633 |
| 49 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.77156213 |
| 50 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.76235203 |
| 51 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.75331480 |
| 52 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.72073342 |
| 53 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.70861378 |
| 54 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.66603940 |
| 55 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.59863460 |
| 56 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.51803991 |
| 57 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.50578683 |
| 58 | RNA degradation_Homo sapiens_hsa03018 | 0.46406645 |
| 59 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.44354386 |
| 60 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.42662465 |
| 61 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.39173749 |
| 62 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.37803952 |
| 63 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.36736522 |
| 64 | Alcoholism_Homo sapiens_hsa05034 | 0.36464029 |
| 65 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.36002307 |
| 66 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.34433570 |
| 67 | Phototransduction_Homo sapiens_hsa04744 | 0.32036762 |
| 68 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.30894471 |
| 69 | Retinol metabolism_Homo sapiens_hsa00830 | 0.30602915 |
| 70 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.29708522 |
| 71 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.28025259 |
| 72 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.27843107 |
| 73 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.24284788 |
| 74 | Purine metabolism_Homo sapiens_hsa00230 | 0.23208626 |
| 75 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.23001279 |
| 76 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.21434242 |
| 77 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.19822769 |
| 78 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.19100101 |
| 79 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.18988627 |
| 80 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.18335856 |
| 81 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.17775387 |
| 82 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.15453496 |
| 83 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.11804751 |
| 84 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.11744586 |
| 85 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.11624872 |
| 86 | HTLV-I infection_Homo sapiens_hsa05166 | 0.11209719 |
| 87 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.11167758 |
| 88 | Phagosome_Homo sapiens_hsa04145 | 0.11133636 |
| 89 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.10778687 |
| 90 | Nicotine addiction_Homo sapiens_hsa05033 | 0.09108930 |
| 91 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.08855278 |
| 92 | Malaria_Homo sapiens_hsa05144 | 0.08641795 |
| 93 | Renin secretion_Homo sapiens_hsa04924 | 0.08171124 |
| 94 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.07899601 |
| 95 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.07200085 |
| 96 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.07186358 |
| 97 | ABC transporters_Homo sapiens_hsa02010 | 0.06699066 |
| 98 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.06683553 |
| 99 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.06622893 |
| 100 | Parkinsons disease_Homo sapiens_hsa05012 | 0.06413509 |

