

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | tooth mineralization (GO:0034505) | 9.49614389 |
| 2 | detection of chemical stimulus involved in sensory perception of smell (GO:0050911) | 8.54764268 |
| 3 | negative regulation of catenin import into nucleus (GO:0035414) | 7.14880854 |
| 4 | centriole replication (GO:0007099) | 6.81816030 |
| 5 | peptidyl-tyrosine autophosphorylation (GO:0038083) | 6.79120224 |
| 6 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 6.59167738 |
| 7 | negative regulation of T-helper cell differentiation (GO:0045623) | 6.59167738 |
| 8 | behavioral response to ethanol (GO:0048149) | 6.57165662 |
| 9 | positive regulation of mitochondrial fission (GO:0090141) | 6.44399083 |
| 10 | activation of protein kinase A activity (GO:0034199) | 6.32419023 |
| 11 | protein K11-linked deubiquitination (GO:0035871) | 6.24089098 |
| 12 | positive regulation of T-helper 1 type immune response (GO:0002827) | 6.16548651 |
| 13 | positive regulation of protein sumoylation (GO:0033235) | 6.13606283 |
| 14 | synaptic transmission, dopaminergic (GO:0001963) | 5.91868378 |
| 15 | regulation of T-helper 1 cell differentiation (GO:0045625) | 5.91178483 |
| 16 | righting reflex (GO:0060013) | 5.82738543 |
| 17 | pentose-phosphate shunt (GO:0006098) | 5.72009069 |
| 18 | locomotory exploration behavior (GO:0035641) | 5.62194651 |
| 19 | cAMP biosynthetic process (GO:0006171) | 5.62039716 |
| 20 | regulation of T-helper 2 cell differentiation (GO:0045628) | 5.61521371 |
| 21 | seminiferous tubule development (GO:0072520) | 5.54518247 |
| 22 | positive regulation of RNA splicing (GO:0033120) | 5.53586015 |
| 23 | dendritic spine morphogenesis (GO:0060997) | 5.47475431 |
| 24 | detection of chemical stimulus involved in sensory perception (GO:0050907) | 5.36635933 |
| 25 | negative regulation of type 2 immune response (GO:0002829) | 5.30592194 |
| 26 | NADPH regeneration (GO:0006740) | 5.28042950 |
| 27 | regulation of corticosteroid hormone secretion (GO:2000846) | 5.27925967 |
| 28 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 5.16266264 |
| 29 | chemosensory behavior (GO:0007635) | 5.08466573 |
| 30 | parturition (GO:0007567) | 5.05627696 |
| 31 | negative regulation of alpha-beta T cell differentiation (GO:0046639) | 5.04622483 |
| 32 | alanine transport (GO:0032328) | 4.89940591 |
| 33 | sequestering of extracellular ligand from receptor (GO:0035581) | 4.80697966 |
| 34 | centriole assembly (GO:0098534) | 4.78103992 |
| 35 | retina layer formation (GO:0010842) | 4.77130325 |
| 36 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 4.63447680 |
| 37 | enteric nervous system development (GO:0048484) | 4.60848217 |
| 38 | arachidonic acid secretion (GO:0050482) | 4.50736296 |
| 39 | icosanoid secretion (GO:0032309) | 4.50736296 |
| 40 | negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067) | 4.50724453 |
| 41 | centrosome duplication (GO:0051298) | 4.48744671 |
| 42 | regulation of mitochondrial fission (GO:0090140) | 4.48394089 |
| 43 | regulation of T-helper 1 type immune response (GO:0002825) | 4.41973718 |
| 44 | regulation of glucocorticoid secretion (GO:2000849) | 4.38981511 |
| 45 | glucose catabolic process (GO:0006007) | 4.31486793 |
| 46 | L-amino acid import (GO:0043092) | 4.15288030 |
| 47 | chaperone-mediated protein transport (GO:0072321) | 4.13063331 |
| 48 | positive regulation of mast cell degranulation (GO:0043306) | 4.08206212 |
| 49 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 4.08206212 |
| 50 | behavioral response to cocaine (GO:0048148) | 3.98690417 |
| 51 | hypothalamus development (GO:0021854) | 3.97891757 |
| 52 | Sertoli cell development (GO:0060009) | 3.97431409 |
| 53 | positive regulation of protein targeting to membrane (GO:0090314) | 3.90836601 |
| 54 | negative regulation of catecholamine secretion (GO:0033604) | 3.90729338 |
| 55 | negative regulation of astrocyte differentiation (GO:0048712) | 3.82455461 |
| 56 | icosanoid transport (GO:0071715) | 3.79974097 |
| 57 | fatty acid derivative transport (GO:1901571) | 3.79974097 |
| 58 | detection of chemical stimulus (GO:0009593) | 3.78583035 |
| 59 | endothelial cell differentiation (GO:0045446) | 3.74567591 |
| 60 | regulation of protein sumoylation (GO:0033233) | 3.71173180 |
| 61 | endocrine hormone secretion (GO:0060986) | 3.67694982 |
| 62 | heterotypic cell-cell adhesion (GO:0034113) | 3.65151624 |
| 63 | tachykinin receptor signaling pathway (GO:0007217) | 3.64598729 |
| 64 | nerve growth factor signaling pathway (GO:0038180) | 3.60469881 |
| 65 | exploration behavior (GO:0035640) | 3.53301319 |
| 66 | regulation of steroid hormone secretion (GO:2000831) | 3.53226846 |
| 67 | basic amino acid transport (GO:0015802) | 3.52776754 |
| 68 | cytokine production involved in immune response (GO:0002367) | 3.48246555 |
| 69 | regulation of voltage-gated calcium channel activity (GO:1901385) | 3.45511998 |
| 70 | neural tube formation (GO:0001841) | 3.44666267 |
| 71 | phosphatidylserine acyl-chain remodeling (GO:0036150) | 3.42962422 |
| 72 | negative regulation of glial cell differentiation (GO:0045686) | 3.42645869 |
| 73 | cellular response to glucagon stimulus (GO:0071377) | 3.38806019 |
| 74 | positive regulation of mast cell activation (GO:0033005) | 3.35950362 |
| 75 | regulation of vesicle fusion (GO:0031338) | 3.35110271 |
| 76 | mitochondrial fusion (GO:0008053) | 3.34039862 |
| 77 | embryonic body morphogenesis (GO:0010172) | 3.30847410 |
| 78 | neuronal ion channel clustering (GO:0045161) | 3.21486249 |
| 79 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.21411066 |
| 80 | positive regulation of sodium ion transmembrane transporter activity (GO:2000651) | 3.21333238 |
| 81 | nephron tubule morphogenesis (GO:0072078) | 3.20291010 |
| 82 | nephron epithelium morphogenesis (GO:0072088) | 3.20291010 |
| 83 | pre-miRNA processing (GO:0031054) | 3.19289739 |
| 84 | ribosomal small subunit biogenesis (GO:0042274) | 3.19100393 |
| 85 | positive regulation of membrane potential (GO:0045838) | 3.17109183 |
| 86 | monoamine transport (GO:0015844) | 3.15760627 |
| 87 | regulation of catecholamine uptake involved in synaptic transmission (GO:0051940) | 3.14879406 |
| 88 | regulation of dopamine uptake involved in synaptic transmission (GO:0051584) | 3.14879406 |
| 89 | body morphogenesis (GO:0010171) | 3.13952167 |
| 90 | phosphatidylglycerol acyl-chain remodeling (GO:0036148) | 3.13163359 |
| 91 | phosphatidylinositol acyl-chain remodeling (GO:0036149) | 3.08433421 |
| 92 | regulation of feeding behavior (GO:0060259) | 3.02245822 |
| 93 | positive regulation of T-helper cell differentiation (GO:0045624) | 3.00459592 |
| 94 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 3.00039508 |
| 95 | embryonic digestive tract morphogenesis (GO:0048557) | 2.96943729 |
| 96 | L-serine transport (GO:0015825) | 2.96026036 |
| 97 | positive regulation of antigen processing and presentation (GO:0002579) | 2.91607090 |
| 98 | regulation of protein targeting to membrane (GO:0090313) | 2.90908378 |
| 99 | protein localization to synapse (GO:0035418) | 2.90231254 |
| 100 | reflex (GO:0060004) | 2.88945242 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 7.51927527 |
| 2 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 6.67837343 |
| 3 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.83011154 |
| 4 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.33839924 |
| 5 | AR_21572438_ChIP-Seq_LNCaP_Human | 3.24017290 |
| 6 | VDR_22108803_ChIP-Seq_LS180_Human | 2.87892640 |
| 7 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 2.55282476 |
| 8 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.32785135 |
| 9 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.19184618 |
| 10 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 2.12961871 |
| 11 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.07277947 |
| 12 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.06354250 |
| 13 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.04597467 |
| 14 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.03751997 |
| 15 | TP53_16413492_ChIP-PET_HCT116_Human | 2.01042893 |
| 16 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.97866411 |
| 17 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.97550472 |
| 18 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.97307424 |
| 19 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.97169626 |
| 20 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.85061233 |
| 21 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.84527959 |
| 22 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.83155286 |
| 23 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.69331191 |
| 24 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.65570427 |
| 25 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.65570427 |
| 26 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.60162213 |
| 27 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.59042117 |
| 28 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.54342571 |
| 29 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.49533344 |
| 30 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.49251558 |
| 31 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.48450044 |
| 32 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.48436015 |
| 33 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.47081934 |
| 34 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.46596692 |
| 35 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.44678391 |
| 36 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.44375339 |
| 37 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.39311264 |
| 38 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.38528952 |
| 39 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.34425762 |
| 40 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.29013131 |
| 41 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.28804661 |
| 42 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.28804661 |
| 43 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.28577483 |
| 44 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.28344529 |
| 45 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.28344529 |
| 46 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.28311101 |
| 47 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.27047099 |
| 48 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.25919299 |
| 49 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.25164697 |
| 50 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.23874983 |
| 51 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.21536586 |
| 52 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.21219873 |
| 53 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.20897191 |
| 54 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.20581606 |
| 55 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.16821872 |
| 56 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.15373306 |
| 57 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.12820150 |
| 58 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.09844502 |
| 59 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.08312579 |
| 60 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.07772434 |
| 61 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.06106673 |
| 62 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.04779382 |
| 63 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.04744162 |
| 64 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.04222871 |
| 65 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.04117426 |
| 66 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.02798626 |
| 67 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.01181669 |
| 68 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.00120596 |
| 69 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.99980751 |
| 70 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.98195968 |
| 71 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.97879741 |
| 72 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.97289540 |
| 73 | RXR_22108803_ChIP-Seq_LS180_Human | 0.96715035 |
| 74 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.96446828 |
| 75 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 0.95728399 |
| 76 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.94207298 |
| 77 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.93660526 |
| 78 | HNFA_21074721_ChIP-Seq_CACO-2_Human | 0.93397141 |
| 79 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.92893316 |
| 80 | STAT3_23295773_ChIP-Seq_U87_Human | 0.91111999 |
| 81 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 0.91034790 |
| 82 | TBL1_22424771_ChIP-Seq_293T_Human | 0.90973669 |
| 83 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.90931430 |
| 84 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 0.89336200 |
| 85 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.89219020 |
| 86 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.88070564 |
| 87 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.87497361 |
| 88 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.87282012 |
| 89 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.86748926 |
| 90 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.85431705 |
| 91 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.84984266 |
| 92 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.84888714 |
| 93 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.84343026 |
| 94 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.82807909 |
| 95 | ETV1_20927104_ChIP-Seq_GIST48_Human | 0.82510744 |
| 96 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.81400734 |
| 97 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 0.80082743 |
| 98 | AR_25329375_ChIP-Seq_VCAP_Human | 0.78501631 |
| 99 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 0.77975038 |
| 100 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 0.77838494 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005084_abnormal_gallbladder_morpholo | 8.37339592 |
| 2 | MP0008961_abnormal_basal_metabolism | 6.60226024 |
| 3 | MP0004133_heterotaxia | 4.31751536 |
| 4 | MP0004130_abnormal_muscle_cell | 3.96372547 |
| 5 | MP0003011_delayed_dark_adaptation | 3.07250174 |
| 6 | MP0005646_abnormal_pituitary_gland | 2.71667808 |
| 7 | MP0009053_abnormal_anal_canal | 2.35076812 |
| 8 | MP0006072_abnormal_retinal_apoptosis | 2.22367318 |
| 9 | MP0003252_abnormal_bile_duct | 2.18785551 |
| 10 | MP0002234_abnormal_pharynx_morphology | 2.10829730 |
| 11 | MP0000537_abnormal_urethra_morphology | 2.08763399 |
| 12 | MP0001905_abnormal_dopamine_level | 2.04353093 |
| 13 | MP0001188_hyperpigmentation | 2.03409800 |
| 14 | MP0003890_abnormal_embryonic-extraembry | 1.98197023 |
| 15 | MP0003787_abnormal_imprinting | 1.89569774 |
| 16 | MP0004264_abnormal_extraembryonic_tissu | 1.85474256 |
| 17 | MP0006276_abnormal_autonomic_nervous | 1.83751142 |
| 18 | MP0005448_abnormal_energy_balance | 1.78019408 |
| 19 | MP0005253_abnormal_eye_physiology | 1.76321692 |
| 20 | MP0008569_lethality_at_weaning | 1.69701970 |
| 21 | MP0005379_endocrine/exocrine_gland_phen | 1.64745902 |
| 22 | MP0002751_abnormal_autonomic_nervous | 1.62241447 |
| 23 | MP0002160_abnormal_reproductive_system | 1.60896771 |
| 24 | MP0009379_abnormal_foot_pigmentation | 1.57293653 |
| 25 | MP0002928_abnormal_bile_duct | 1.54816841 |
| 26 | MP0003806_abnormal_nucleotide_metabolis | 1.49859909 |
| 27 | MP0001299_abnormal_eye_distance/ | 1.45328855 |
| 28 | MP0008789_abnormal_olfactory_epithelium | 1.44243943 |
| 29 | MP0003119_abnormal_digestive_system | 1.41963386 |
| 30 | MP0002184_abnormal_innervation | 1.37832247 |
| 31 | MP0001270_distended_abdomen | 1.37527619 |
| 32 | MP0002108_abnormal_muscle_morphology | 1.36946242 |
| 33 | MP0003121_genomic_imprinting | 1.34699977 |
| 34 | MP0000631_abnormal_neuroendocrine_gland | 1.33056851 |
| 35 | MP0002572_abnormal_emotion/affect_behav | 1.32042780 |
| 36 | MP0002909_abnormal_adrenal_gland | 1.31914634 |
| 37 | MP0002653_abnormal_ependyma_morphology | 1.31009891 |
| 38 | MP0001542_abnormal_bone_strength | 1.27889154 |
| 39 | MP0005365_abnormal_bile_salt | 1.23340401 |
| 40 | MP0005645_abnormal_hypothalamus_physiol | 1.22831570 |
| 41 | MP0005394_taste/olfaction_phenotype | 1.22384268 |
| 42 | MP0005499_abnormal_olfactory_system | 1.22384268 |
| 43 | MP0003123_paternal_imprinting | 1.21672727 |
| 44 | MP0005220_abnormal_exocrine_pancreas | 1.20088706 |
| 45 | MP0003329_amyloid_beta_deposits | 1.18963462 |
| 46 | MP0004858_abnormal_nervous_system | 1.16757779 |
| 47 | MP0002638_abnormal_pupillary_reflex | 1.11789175 |
| 48 | MP0003136_yellow_coat_color | 1.07617252 |
| 49 | MP0004145_abnormal_muscle_electrophysio | 1.06742203 |
| 50 | MP0002102_abnormal_ear_morphology | 1.05761658 |
| 51 | MP0005257_abnormal_intraocular_pressure | 1.05322074 |
| 52 | MP0002882_abnormal_neuron_morphology | 1.04513898 |
| 53 | MP0000639_abnormal_adrenal_gland | 1.04312524 |
| 54 | MP0006292_abnormal_olfactory_placode | 0.98905551 |
| 55 | MP0004272_abnormal_basement_membrane | 0.97718832 |
| 56 | MP0003880_abnormal_central_pattern | 0.95060296 |
| 57 | MP0000049_abnormal_middle_ear | 0.93741934 |
| 58 | MP0002734_abnormal_mechanical_nocicepti | 0.92882289 |
| 59 | MP0001529_abnormal_vocalization | 0.92861127 |
| 60 | MP0000604_amyloidosis | 0.92432068 |
| 61 | MP0005551_abnormal_eye_electrophysiolog | 0.88700186 |
| 62 | MP0002752_abnormal_somatic_nervous | 0.87369765 |
| 63 | MP0005391_vision/eye_phenotype | 0.87108837 |
| 64 | MP0009745_abnormal_behavioral_response | 0.83826921 |
| 65 | MP0000778_abnormal_nervous_system | 0.79819897 |
| 66 | MP0001944_abnormal_pancreas_morphology | 0.78521510 |
| 67 | MP0002063_abnormal_learning/memory/cond | 0.76315658 |
| 68 | MP0003938_abnormal_ear_development | 0.75656068 |
| 69 | MP0002282_abnormal_trachea_morphology | 0.75353648 |
| 70 | MP0003953_abnormal_hormone_level | 0.73216555 |
| 71 | MP0002822_catalepsy | 0.72842567 |
| 72 | MP0005369_muscle_phenotype | 0.72303780 |
| 73 | MP0002078_abnormal_glucose_homeostasis | 0.69192870 |
| 74 | MP0000955_abnormal_spinal_cord | 0.68941625 |
| 75 | MP0001970_abnormal_pain_threshold | 0.68910270 |
| 76 | MP0005195_abnormal_posterior_eye | 0.68488304 |
| 77 | MP0003718_maternal_effect | 0.68106366 |
| 78 | MP0003635_abnormal_synaptic_transmissio | 0.67590579 |
| 79 | MP0002233_abnormal_nose_morphology | 0.67549779 |
| 80 | MP0005165_increased_susceptibility_to | 0.67427941 |
| 81 | MP0002693_abnormal_pancreas_physiology | 0.67335977 |
| 82 | MP0002272_abnormal_nervous_system | 0.66502014 |
| 83 | MP0005389_reproductive_system_phenotype | 0.65378885 |
| 84 | MP0009046_muscle_twitch | 0.64876190 |
| 85 | MP0005408_hypopigmentation | 0.63481982 |
| 86 | MP0002229_neurodegeneration | 0.63368037 |
| 87 | MP0003937_abnormal_limbs/digits/tail_de | 0.62845914 |
| 88 | MP0004134_abnormal_chest_morphology | 0.62206615 |
| 89 | MP0002066_abnormal_motor_capabilities/c | 0.61342588 |
| 90 | MP0001175_abnormal_lung_morphology | 0.61132068 |
| 91 | MP0008875_abnormal_xenobiotic_pharmacok | 0.60076923 |
| 92 | MP0009764_decreased_sensitivity_to | 0.59950955 |
| 93 | MP0005085_abnormal_gallbladder_physiolo | 0.58712830 |
| 94 | MP0002067_abnormal_sensory_capabilities | 0.57928387 |
| 95 | MP0000759_abnormal_skeletal_muscle | 0.55554487 |
| 96 | MP0010386_abnormal_urinary_bladder | 0.54554034 |
| 97 | MP0002109_abnormal_limb_morphology | 0.54371863 |
| 98 | MP0003861_abnormal_nervous_system | 0.54011656 |
| 99 | MP0002152_abnormal_brain_morphology | 0.53818710 |
| 100 | MP0003942_abnormal_urinary_system | 0.52258736 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Patent foramen ovale (HP:0001655) | 6.78516080 |
| 2 | Abnormal hair whorl (HP:0010721) | 6.75851342 |
| 3 | Bile duct proliferation (HP:0001408) | 6.67530942 |
| 4 | Abnormal biliary tract physiology (HP:0012439) | 6.67530942 |
| 5 | Overgrowth (HP:0001548) | 5.97960916 |
| 6 | Amelogenesis imperfecta (HP:0000705) | 5.95330999 |
| 7 | Abnormality of the right ventricle (HP:0001707) | 5.69049311 |
| 8 | Abnormality of calcium-phosphate metabolism (HP:0100530) | 5.40348953 |
| 9 | Osteomalacia (HP:0002749) | 5.32125861 |
| 10 | Abnormality of renal resorption (HP:0011038) | 5.19285035 |
| 11 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 5.08477990 |
| 12 | Lip pit (HP:0100267) | 4.78198067 |
| 13 | Abnormality of dental color (HP:0011073) | 4.57151428 |
| 14 | Abnormality of the dental pulp (HP:0006479) | 4.25309712 |
| 15 | Depressed nasal tip (HP:0000437) | 4.15795328 |
| 16 | Molar tooth sign on MRI (HP:0002419) | 3.60029243 |
| 17 | Abnormality of midbrain morphology (HP:0002418) | 3.60029243 |
| 18 | Hypoplastic pelvis (HP:0008839) | 3.56583838 |
| 19 | Polyuria (HP:0000103) | 3.37080373 |
| 20 | Morphological abnormality of the middle ear (HP:0008609) | 3.15644194 |
| 21 | Abnormality of the neuromuscular junction (HP:0003398) | 3.10254699 |
| 22 | Fatigable weakness (HP:0003473) | 3.10254699 |
| 23 | 3-Methylglutaconic aciduria (HP:0003535) | 3.08225962 |
| 24 | Abnormal urine output (HP:0012590) | 3.08074031 |
| 25 | Spastic tetraparesis (HP:0001285) | 3.05071087 |
| 26 | Chronic bronchitis (HP:0004469) | 2.99415734 |
| 27 | Abnormality of renal excretion (HP:0011036) | 2.94822685 |
| 28 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 2.92341924 |
| 29 | Decreased muscle mass (HP:0003199) | 2.90115801 |
| 30 | Abnormality of the nasal septum (HP:0000419) | 2.87321738 |
| 31 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.83021598 |
| 32 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.82138034 |
| 33 | Gonadotropin excess (HP:0000837) | 2.75597331 |
| 34 | Abolished electroretinogram (ERG) (HP:0000550) | 2.65522985 |
| 35 | Abnormality of the distal phalanges of the toes (HP:0010182) | 2.57906121 |
| 36 | Cortical dysplasia (HP:0002539) | 2.57063036 |
| 37 | Rhinitis (HP:0012384) | 2.53026732 |
| 38 | Abnormality of the umbilical cord (HP:0010881) | 2.47203961 |
| 39 | Wide nose (HP:0000445) | 2.34125322 |
| 40 | Short nail (HP:0001799) | 2.33213083 |
| 41 | Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026) | 2.30517341 |
| 42 | Short 1st metacarpal (HP:0010034) | 2.30517341 |
| 43 | Submucous cleft hard palate (HP:0000176) | 2.30283619 |
| 44 | Abnormality of the middle phalanges of the toes (HP:0010183) | 2.24986151 |
| 45 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 2.23041565 |
| 46 | Progressive microcephaly (HP:0000253) | 2.22933139 |
| 47 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 2.18058554 |
| 48 | Anosmia (HP:0000458) | 2.14388525 |
| 49 | Fused cervical vertebrae (HP:0002949) | 2.12936431 |
| 50 | Posterior subcapsular cataract (HP:0007787) | 2.11999564 |
| 51 | Nephrocalcinosis (HP:0000121) | 2.11258897 |
| 52 | Abnormal finger flexion creases (HP:0006143) | 2.10584122 |
| 53 | Abnormality of the 1st metacarpal (HP:0010009) | 2.07789567 |
| 54 | Humeroradial synostosis (HP:0003041) | 2.07321122 |
| 55 | Synostosis involving the elbow (HP:0003938) | 2.07321122 |
| 56 | Rib fusion (HP:0000902) | 2.06886745 |
| 57 | Absent phalangeal crease (HP:0006109) | 1.99267596 |
| 58 | Round ear (HP:0100830) | 1.96566240 |
| 59 | Rocker bottom foot (HP:0001838) | 1.95612846 |
| 60 | Congenital malformation of the right heart (HP:0011723) | 1.95046121 |
| 61 | Double outlet right ventricle (HP:0001719) | 1.95046121 |
| 62 | Tarsal synostosis (HP:0008368) | 1.95043390 |
| 63 | Sparse lateral eyebrow (HP:0005338) | 1.92037230 |
| 64 | Severe global developmental delay (HP:0011344) | 1.90980119 |
| 65 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 1.88212603 |
| 66 | Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173) | 1.86745528 |
| 67 | Short 5th finger (HP:0009237) | 1.86132099 |
| 68 | Synostosis involving bones of the lower limbs (HP:0009138) | 1.82948195 |
| 69 | Synostosis involving bones of the feet (HP:0009140) | 1.82948195 |
| 70 | Adrenal hypoplasia (HP:0000835) | 1.82913256 |
| 71 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.81905909 |
| 72 | Small for gestational age (HP:0001518) | 1.81035361 |
| 73 | Drooling (HP:0002307) | 1.80682634 |
| 74 | Prolonged QT interval (HP:0001657) | 1.79937724 |
| 75 | Mildly elevated creatine phosphokinase (HP:0008180) | 1.79353476 |
| 76 | Hyperphosphaturia (HP:0003109) | 1.77974774 |
| 77 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.75408271 |
| 78 | Aplasia/Hypoplasia of the 5th finger (HP:0006262) | 1.74521405 |
| 79 | Myelomeningocele (HP:0002475) | 1.74177946 |
| 80 | Hypophosphatemic rickets (HP:0004912) | 1.73606918 |
| 81 | Deep palmar crease (HP:0006191) | 1.72695663 |
| 82 | Hypoparathyroidism (HP:0000829) | 1.71034836 |
| 83 | Abnormality of the fovea (HP:0000493) | 1.69870812 |
| 84 | Long foot (HP:0001833) | 1.69246733 |
| 85 | Short hallux (HP:0010109) | 1.67533476 |
| 86 | Oculomotor apraxia (HP:0000657) | 1.67312012 |
| 87 | Abnormal urine phosphate concentration (HP:0012599) | 1.66628984 |
| 88 | Excessive salivation (HP:0003781) | 1.66163520 |
| 89 | Short humerus (HP:0005792) | 1.66092648 |
| 90 | Nephronophthisis (HP:0000090) | 1.65853448 |
| 91 | Cystic hygroma (HP:0000476) | 1.65429643 |
| 92 | Absent septum pellucidum (HP:0001331) | 1.64245271 |
| 93 | Lipoatrophy (HP:0100578) | 1.63492022 |
| 94 | Slender long bone (HP:0003100) | 1.63244949 |
| 95 | Gonadal dysgenesis (HP:0000133) | 1.63204221 |
| 96 | Primary amenorrhea (HP:0000786) | 1.63022583 |
| 97 | Microretrognathia (HP:0000308) | 1.61756431 |
| 98 | Short phalanx of the thumb (HP:0009660) | 1.61692021 |
| 99 | Thyroiditis (HP:0100646) | 1.61283342 |
| 100 | Hypoplasia of dental enamel (HP:0006297) | 1.59210084 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MUSK | 7.97237366 |
| 2 | NTRK2 | 6.57675498 |
| 3 | AKT3 | 2.99210705 |
| 4 | PINK1 | 2.16849399 |
| 5 | WNK3 | 2.00404714 |
| 6 | BMPR1B | 10.3428072 |
| 7 | MAP4K1 | 1.93524703 |
| 8 | MAP3K4 | 1.88787562 |
| 9 | BLK | 1.64737595 |
| 10 | STK3 | 1.53871288 |
| 11 | CAMK1D | 1.37079696 |
| 12 | BRAF | 1.32322714 |
| 13 | MAP2K7 | 1.32111217 |
| 14 | CAMK1G | 1.23274933 |
| 15 | ADRBK2 | 1.22339560 |
| 16 | ICK | 1.16180203 |
| 17 | SGK223 | 1.14019934 |
| 18 | SGK494 | 1.14019934 |
| 19 | WNK4 | 1.09406307 |
| 20 | NTRK3 | 1.08199180 |
| 21 | CDC42BPA | 0.91464027 |
| 22 | OBSCN | 0.88832161 |
| 23 | ARAF | 0.88757462 |
| 24 | TYRO3 | 0.82791057 |
| 25 | DYRK2 | 0.80289498 |
| 26 | RIPK4 | 0.69855470 |
| 27 | PAK3 | 0.68978667 |
| 28 | PRKCQ | 0.68668074 |
| 29 | BMPR2 | 0.66387614 |
| 30 | CDK5 | 0.64715452 |
| 31 | GRK1 | 0.62118692 |
| 32 | MINK1 | 0.60767402 |
| 33 | STK39 | 0.60619419 |
| 34 | PRKCG | 0.56857776 |
| 35 | FRK | 0.55602531 |
| 36 | NTRK1 | 0.53564921 |
| 37 | SGK2 | 0.52920440 |
| 38 | MYLK | 0.52246972 |
| 39 | DYRK3 | 0.48180901 |
| 40 | TNK2 | 0.47995901 |
| 41 | INSRR | 0.47599728 |
| 42 | PRKACB | 0.46172845 |
| 43 | PNCK | 0.45839971 |
| 44 | FYN | 0.44003131 |
| 45 | TAOK3 | 0.43815718 |
| 46 | MATK | 0.43326625 |
| 47 | ROCK2 | 0.39462557 |
| 48 | MAP3K9 | 0.39089926 |
| 49 | SRC | 0.38513901 |
| 50 | PRKACA | 0.37631007 |
| 51 | MAPK13 | 0.36874160 |
| 52 | STK11 | 0.36464995 |
| 53 | PRKAA1 | 0.34746402 |
| 54 | RPS6KA6 | 0.33067007 |
| 55 | UHMK1 | 0.32083800 |
| 56 | ABL1 | 0.31823514 |
| 57 | TIE1 | 0.31289561 |
| 58 | RPS6KC1 | 0.31245035 |
| 59 | RPS6KL1 | 0.31245035 |
| 60 | SGK3 | 0.30802752 |
| 61 | EPHB2 | 0.30362775 |
| 62 | CAMK1 | 0.30245874 |
| 63 | OXSR1 | 0.28594312 |
| 64 | EPHA4 | 0.28395778 |
| 65 | RPS6KA1 | 0.28216422 |
| 66 | BRSK1 | 0.27245434 |
| 67 | PRKCD | 0.27176191 |
| 68 | CAMK2D | 0.27145454 |
| 69 | PRKACG | 0.27138463 |
| 70 | ERBB2 | 0.26642106 |
| 71 | PLK4 | 0.25757737 |
| 72 | CAMK4 | 0.24799395 |
| 73 | STK16 | 0.24555057 |
| 74 | HIPK2 | 0.23777302 |
| 75 | ADRBK1 | 0.23569409 |
| 76 | CSNK1D | 0.23510645 |
| 77 | ROCK1 | 0.23194970 |
| 78 | CDK3 | 0.22291922 |
| 79 | CAMKK1 | 0.18895165 |
| 80 | TLK1 | 0.17175943 |
| 81 | FGFR1 | 0.16931951 |
| 82 | CAMK2A | 0.16889191 |
| 83 | MAPK15 | 0.16306033 |
| 84 | CSNK1A1 | 0.16134368 |
| 85 | PIM2 | 0.16024507 |
| 86 | AKT1 | 0.14518755 |
| 87 | PRKCA | 0.13419909 |
| 88 | MAP2K4 | 0.12589523 |
| 89 | MAPK11 | 0.12390229 |
| 90 | PIK3CA | 0.11621326 |
| 91 | NEK2 | 0.10991124 |
| 92 | CDK19 | 0.10714013 |
| 93 | GRK7 | 0.10512467 |
| 94 | INSR | 0.10436163 |
| 95 | SCYL2 | 0.10415049 |
| 96 | RPS6KB1 | 0.09773998 |
| 97 | NEK9 | 0.09182656 |
| 98 | PRKG1 | 0.08951057 |
| 99 | MOS | 0.08335152 |
| 100 | NME2 | 0.08267680 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Olfactory transduction_Homo sapiens_hsa04740 | 4.27686416 |
| 2 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 3.25907845 |
| 3 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 2.66140428 |
| 4 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 2.54230204 |
| 5 | Sulfur metabolism_Homo sapiens_hsa00920 | 2.49906568 |
| 6 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 2.47309965 |
| 7 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.41330154 |
| 8 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 2.39887102 |
| 9 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.38209661 |
| 10 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.17357395 |
| 11 | Circadian entrainment_Homo sapiens_hsa04713 | 2.01695461 |
| 12 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.99826680 |
| 13 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.99500389 |
| 14 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.92202156 |
| 15 | Bile secretion_Homo sapiens_hsa04976 | 1.90105767 |
| 16 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.89542125 |
| 17 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 1.87074584 |
| 18 | Sulfur relay system_Homo sapiens_hsa04122 | 1.80248992 |
| 19 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.69699550 |
| 20 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.68284244 |
| 21 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.63237483 |
| 22 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.63076166 |
| 23 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.62122104 |
| 24 | Salivary secretion_Homo sapiens_hsa04970 | 1.61737295 |
| 25 | Pancreatic secretion_Homo sapiens_hsa04972 | 1.60225368 |
| 26 | GABAergic synapse_Homo sapiens_hsa04727 | 1.59761211 |
| 27 | Cocaine addiction_Homo sapiens_hsa05030 | 1.58424223 |
| 28 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.57666606 |
| 29 | Insulin secretion_Homo sapiens_hsa04911 | 1.56271219 |
| 30 | Morphine addiction_Homo sapiens_hsa05032 | 1.55547323 |
| 31 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.54016696 |
| 32 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.52775810 |
| 33 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.51074540 |
| 34 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.43740235 |
| 35 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.41059289 |
| 36 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.36894360 |
| 37 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.36020565 |
| 38 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.31332621 |
| 39 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.26127948 |
| 40 | Taste transduction_Homo sapiens_hsa04742 | 1.24743975 |
| 41 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.22449083 |
| 42 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 1.21633444 |
| 43 | Parkinsons disease_Homo sapiens_hsa05012 | 1.21493518 |
| 44 | Gap junction_Homo sapiens_hsa04540 | 1.16607388 |
| 45 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.13581556 |
| 46 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.13346059 |
| 47 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.12457670 |
| 48 | Melanogenesis_Homo sapiens_hsa04916 | 1.10164588 |
| 49 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.97149851 |
| 50 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.96009873 |
| 51 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.95101694 |
| 52 | Endometrial cancer_Homo sapiens_hsa05213 | 0.91036821 |
| 53 | Nicotine addiction_Homo sapiens_hsa05033 | 0.88803639 |
| 54 | Long-term depression_Homo sapiens_hsa04730 | 0.88422280 |
| 55 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.85615104 |
| 56 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.79245690 |
| 57 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.78455325 |
| 58 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.76381217 |
| 59 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.73729021 |
| 60 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.69804057 |
| 61 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.68356093 |
| 62 | Alcoholism_Homo sapiens_hsa05034 | 0.67912501 |
| 63 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.67874774 |
| 64 | Mineral absorption_Homo sapiens_hsa04978 | 0.67733923 |
| 65 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.66885562 |
| 66 | Platelet activation_Homo sapiens_hsa04611 | 0.63623066 |
| 67 | Phototransduction_Homo sapiens_hsa04744 | 0.62536907 |
| 68 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.60846996 |
| 69 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.60218352 |
| 70 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.59042860 |
| 71 | Protein export_Homo sapiens_hsa03060 | 0.58408862 |
| 72 | Huntingtons disease_Homo sapiens_hsa05016 | 0.58009364 |
| 73 | Retinol metabolism_Homo sapiens_hsa00830 | 0.56464259 |
| 74 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.53520150 |
| 75 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.53419467 |
| 76 | RNA degradation_Homo sapiens_hsa03018 | 0.53005926 |
| 77 | Circadian rhythm_Homo sapiens_hsa04710 | 0.52762545 |
| 78 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.51335079 |
| 79 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.51179870 |
| 80 | Colorectal cancer_Homo sapiens_hsa05210 | 0.50553665 |
| 81 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.48210408 |
| 82 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.46818994 |
| 83 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.46800743 |
| 84 | Alzheimers disease_Homo sapiens_hsa05010 | 0.44867692 |
| 85 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.44499532 |
| 86 | Ribosome_Homo sapiens_hsa03010 | 0.43621900 |
| 87 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.41014522 |
| 88 | Long-term potentiation_Homo sapiens_hsa04720 | 0.40380708 |
| 89 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.34467336 |
| 90 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.34026466 |
| 91 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.32328016 |
| 92 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.32087782 |
| 93 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.31597226 |
| 94 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.30215261 |
| 95 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.28831951 |
| 96 | Pathways in cancer_Homo sapiens_hsa05200 | 0.27591809 |
| 97 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.27584030 |
| 98 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.26486772 |
| 99 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.24883863 |
| 100 | Renin secretion_Homo sapiens_hsa04924 | 0.22458546 |

