OR7E154P

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1auditory receptor cell differentiation (GO:0042491)8.40580505
2cerebellar Purkinje cell layer development (GO:0021680)6.97960732
3central nervous system myelination (GO:0022010)5.78946107
4axon ensheathment in central nervous system (GO:0032291)5.78946107
5neuronal ion channel clustering (GO:0045161)5.44654056
6regulation of female receptivity (GO:0045924)4.94667779
7neuronal action potential propagation (GO:0019227)4.85718878
8synaptic vesicle maturation (GO:0016188)4.83694061
9glutamate secretion (GO:0014047)4.73080982
10synaptic vesicle docking involved in exocytosis (GO:0016081)4.72138611
11regulation of short-term neuronal synaptic plasticity (GO:0048172)4.70794200
12positive regulation of sodium ion transmembrane transporter activity (GO:2000651)4.64924600
13inner ear receptor cell differentiation (GO:0060113)4.55651430
14positive regulation of mitochondrial fission (GO:0090141)4.36606587
15response to dietary excess (GO:0002021)4.23023206
16female mating behavior (GO:0060180)4.10730788
17gamma-aminobutyric acid transport (GO:0015812)4.01398861
18synaptic transmission, glutamatergic (GO:0035249)3.89775742
19glyoxylate metabolic process (GO:0046487)3.89762210
20positive regulation of sodium ion transmembrane transport (GO:1902307)3.89669508
21dopamine biosynthetic process (GO:0042416)3.83950027
22hair cell differentiation (GO:0035315)3.81668293
23hypothalamus development (GO:0021854)3.75473125
24neurotransmitter secretion (GO:0007269)3.69277804
25membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.66559246
26behavioral response to nicotine (GO:0035095)3.65446326
27exploration behavior (GO:0035640)3.64412971
28glycerophospholipid catabolic process (GO:0046475)3.64102146
29regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.63952906
30locomotory exploration behavior (GO:0035641)3.63398303
31protein polyglutamylation (GO:0018095)3.60035279
32substrate-independent telencephalic tangential interneuron migration (GO:0021843)3.59560109
33substrate-independent telencephalic tangential migration (GO:0021826)3.59560109
34neuron-neuron synaptic transmission (GO:0007270)3.48030893
35synaptic vesicle exocytosis (GO:0016079)3.41104401
36regulation of glutamate receptor signaling pathway (GO:1900449)3.40048853
37regulation of synaptic vesicle exocytosis (GO:2000300)3.38776375
38toxin metabolic process (GO:0009404)3.37889018
39mechanoreceptor differentiation (GO:0042490)3.36414824
40microtubule severing (GO:0051013)3.34992795
41regulation of neuronal synaptic plasticity (GO:0048168)3.34391730
42negative regulation of synaptic transmission, GABAergic (GO:0032229)3.29807830
43regulation of glutamate secretion (GO:0014048)3.25346651
44postsynaptic membrane organization (GO:0001941)3.23659480
45limb development (GO:0060173)3.20985420
46appendage development (GO:0048736)3.20985420
47negative regulation of amino acid transport (GO:0051956)3.16201496
48neuron cell-cell adhesion (GO:0007158)3.15449815
49pattern specification involved in kidney development (GO:0061004)3.14108034
50regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.12530608
51regulation of synaptic vesicle transport (GO:1902803)3.07967043
52establishment of mitochondrion localization (GO:0051654)3.07074525
53neuromuscular synaptic transmission (GO:0007274)3.03982992
54ionotropic glutamate receptor signaling pathway (GO:0035235)3.02407831
55regulation of glycogen (starch) synthase activity (GO:2000465)3.02270780
56transmission of nerve impulse (GO:0019226)3.01765764
57regulation of mitochondrial fission (GO:0090140)3.01489315
58cell migration in hindbrain (GO:0021535)3.00361034
59positive regulation of neurotransmitter transport (GO:0051590)2.94142676
60presynaptic membrane organization (GO:0097090)2.94027955
61positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.93600729
62neurotransmitter transport (GO:0006836)2.92843084
63regulation of sodium ion transmembrane transporter activity (GO:2000649)2.92279447
64receptor recycling (GO:0001881)2.89673678
65astrocyte differentiation (GO:0048708)2.89501776
66detection of temperature stimulus (GO:0016048)2.89359554
67killing of cells in other organism involved in symbiotic interaction (GO:0051883)2.88853380
68disruption of cells of other organism involved in symbiotic interaction (GO:0051818)2.88853380
69synaptic vesicle endocytosis (GO:0048488)2.88287850
70positive regulation of sodium ion transport (GO:0010765)2.88184541
71detection of temperature stimulus involved in sensory perception (GO:0050961)2.88009751
72detection of temperature stimulus involved in sensory perception of pain (GO:0050965)2.88009751
73regulation of membrane repolarization (GO:0060306)2.87642607
74axonal fasciculation (GO:0007413)2.86026920
75behavioral response to ethanol (GO:0048149)2.85637151
76neurotransmitter-gated ion channel clustering (GO:0072578)2.83559040
77mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.83164261
78neuronal action potential (GO:0019228)2.82895652
79regulation of neurotransmitter levels (GO:0001505)2.82394753
80positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.82351277
81positive regulation of neurotransmitter secretion (GO:0001956)2.81760704
82regulation of voltage-gated calcium channel activity (GO:1901385)2.78749924
83regulation of neurotransmitter secretion (GO:0046928)2.77929633
84positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.77223527
85urinary tract smooth muscle contraction (GO:0014848)2.77050777
86synapse organization (GO:0050808)2.76879098
87behavioral defense response (GO:0002209)2.76525161
88behavioral fear response (GO:0001662)2.76525161
89phosphorylated carbohydrate dephosphorylation (GO:0046838)2.75316185
90inositol phosphate dephosphorylation (GO:0046855)2.75316185
91regulation of cAMP-dependent protein kinase activity (GO:2000479)2.75278922
92ATP synthesis coupled proton transport (GO:0015986)2.71968240
93energy coupled proton transport, down electrochemical gradient (GO:0015985)2.71968240
94regulation of synapse structural plasticity (GO:0051823)2.71006890
95mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.68370607
96neuron recognition (GO:0008038)2.67803186
97regulation of sodium ion transmembrane transport (GO:1902305)2.67096548
98cerebral cortex radially oriented cell migration (GO:0021799)2.66461243
99energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.66017222
100ATP hydrolysis coupled proton transport (GO:0015991)2.66017222

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.32379246
2NR4A2_19515692_ChIP-ChIP_MN9D_Mouse4.44318864
3CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons3.78925199
4REST_21632747_ChIP-Seq_MESCs_Mouse3.07283592
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.96192803
6SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.89772674
7IKZF1_21737484_ChIP-ChIP_HCT116_Human2.64758814
8SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.60922148
9REST_18959480_ChIP-ChIP_MESCs_Mouse2.58326687
10EZH2_27304074_Chip-Seq_ESCs_Mouse2.55289360
11JARID2_20075857_ChIP-Seq_MESCs_Mouse2.53996024
12GBX2_23144817_ChIP-Seq_PC3_Human2.52919089
13SUZ12_27294783_Chip-Seq_ESCs_Mouse2.50792123
14EED_16625203_ChIP-ChIP_MESCs_Mouse2.43854877
15SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.39358327
16EZH2_27294783_Chip-Seq_ESCs_Mouse2.39102847
17EZH2_18974828_ChIP-Seq_MESCs_Mouse2.36146592
18RNF2_18974828_ChIP-Seq_MESCs_Mouse2.36146592
19RCOR2_21632747_ChIP-Seq_MESCs_Mouse2.29906560
20SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.28562700
21RNF2_27304074_Chip-Seq_ESCs_Mouse2.21616390
22MTF2_20144788_ChIP-Seq_MESCs_Mouse2.16413150
23CBX2_27304074_Chip-Seq_ESCs_Mouse2.10008955
24DROSHA_22980978_ChIP-Seq_HELA_Human2.06265204
25SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.02536963
26SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.94335229
27RARB_27405468_Chip-Seq_BRAIN_Mouse1.87395949
28RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.84876325
29PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.83154904
30RNF2_27304074_Chip-Seq_NSC_Mouse1.80226748
31CTBP2_25329375_ChIP-Seq_LNCAP_Human1.78024440
32ERG_21242973_ChIP-ChIP_JURKAT_Human1.75104787
33TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.73317440
34MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.69688831
35BMI1_23680149_ChIP-Seq_NPCS_Mouse1.63116033
36ZFP57_27257070_Chip-Seq_ESCs_Mouse1.53825245
37ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.49748843
38RING1B_27294783_Chip-Seq_ESCs_Mouse1.46422552
39CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.45470807
40RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.43989874
41P53_22127205_ChIP-Seq_FIBROBLAST_Human1.41466280
42RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.38399856
43OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.34778285
44MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.29275256
45DNAJC2_21179169_ChIP-ChIP_NT2_Human1.26614677
46GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.22949745
47SMAD4_21799915_ChIP-Seq_A2780_Human1.20826876
48POU3F2_20337985_ChIP-ChIP_501MEL_Human1.18392809
49MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.18278283
50TOP2B_26459242_ChIP-Seq_MCF-7_Human1.18275060
51TAF15_26573619_Chip-Seq_HEK293_Human1.17470454
52SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.17048060
53PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.14327912
54PIAS1_25552417_ChIP-Seq_VCAP_Human1.13523159
55EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.12668057
56FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.12462384
57POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.11684120
58TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.11684120
59HTT_18923047_ChIP-ChIP_STHdh_Human1.11564314
60CTCF_27219007_Chip-Seq_Bcells_Human1.10188270
61OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.08914061
62P300_19829295_ChIP-Seq_ESCs_Human1.07826574
63SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.05131933
64SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.03460677
65ZFP281_18757296_ChIP-ChIP_E14_Mouse0.97250048
66SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.95614094
67MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.95479313
68SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.94651756
69TP53_20018659_ChIP-ChIP_R1E_Mouse0.93049744
70CTBP1_25329375_ChIP-Seq_LNCAP_Human0.90921985
71ETV2_25802403_ChIP-Seq_MESCs_Mouse0.90469851
72TRIM28_21343339_ChIP-Seq_HEK293_Human0.89644636
73TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.89429501
74KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.88904610
75SMAD3_21741376_ChIP-Seq_ESCs_Human0.88513642
76SOX2_21211035_ChIP-Seq_LN229_Gbm0.88111256
77MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.87099778
78RING1B_27294783_Chip-Seq_NPCs_Mouse0.86263162
79ZNF274_21170338_ChIP-Seq_K562_Hela0.85244761
80REST_19997604_ChIP-ChIP_NEURONS_Mouse0.83051059
81TCF4_23295773_ChIP-Seq_U87_Human0.82798810
82TET1_21490601_ChIP-Seq_MESCs_Mouse0.82651130
83ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.81952108
84SOX9_26525672_Chip-Seq_HEART_Mouse0.81699368
85TBX3_20139965_ChIP-Seq_MESCs_Mouse0.80254824
86TBX3_20139965_ChIP-Seq_ESCs_Mouse0.79861704
87SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.79499073
88NR3C1_21868756_ChIP-Seq_MCF10A_Human0.79376489
89PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.76094732
90AR_19668381_ChIP-Seq_PC3_Human0.75891334
91YAP1_20516196_ChIP-Seq_MESCs_Mouse0.75865823
92TAL1_26923725_Chip-Seq_HPCs_Mouse0.75413211
93BCAT_22108803_ChIP-Seq_LS180_Human0.75101549
94CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.74868492
95SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.73420938
96STAT3_23295773_ChIP-Seq_U87_Human0.73388131
97SOX9_26525672_Chip-Seq_Limbbuds_Mouse0.72824402
98KLF5_20875108_ChIP-Seq_MESCs_Mouse0.72706103
99EWS_26573619_Chip-Seq_HEK293_Human0.72391355
100MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.71304593

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.06957564
2MP0004859_abnormal_synaptic_plasticity4.05580643
3MP0005423_abnormal_somatic_nervous3.89637883
4MP0003787_abnormal_imprinting3.78668501
5MP0009780_abnormal_chondrocyte_physiolo3.34978098
6MP0009046_muscle_twitch3.05995781
7MP0001968_abnormal_touch/_nociception2.75308594
8MP0003879_abnormal_hair_cell2.73268374
9MP0002064_seizures2.72929350
10MP0002736_abnormal_nociception_after2.69705544
11MP0003635_abnormal_synaptic_transmissio2.63387534
12MP0009745_abnormal_behavioral_response2.61677378
13MP0002063_abnormal_learning/memory/cond2.54816454
14MP0002272_abnormal_nervous_system2.54064171
15MP0003122_maternal_imprinting2.37832251
16MP0004270_analgesia2.37293019
17MP0002572_abnormal_emotion/affect_behav2.16591831
18MP0002876_abnormal_thyroid_physiology2.14194570
19MP0005645_abnormal_hypothalamus_physiol2.12266856
20MP0006276_abnormal_autonomic_nervous2.09233344
21MP0002734_abnormal_mechanical_nocicepti2.09188617
22MP0003123_paternal_imprinting2.08981067
23MP0005646_abnormal_pituitary_gland1.98448888
24MP0004885_abnormal_endolymph1.93207504
25MP0004145_abnormal_muscle_electrophysio1.91860466
26MP0001486_abnormal_startle_reflex1.89332475
27MP0000778_abnormal_nervous_system1.88038058
28MP0002837_dystrophic_cardiac_calcinosis1.81559353
29MP0003121_genomic_imprinting1.80024266
30MP0004147_increased_porphyrin_level1.75220398
31MP0001984_abnormal_olfaction1.72379056
32MP0003646_muscle_fatigue1.65647207
33MP0002067_abnormal_sensory_capabilities1.65598158
34MP0001529_abnormal_vocalization1.62823948
35MP0004742_abnormal_vestibular_system1.54133628
36MP0002557_abnormal_social/conspecific_i1.53496325
37MP0002184_abnormal_innervation1.53082155
38MP0005551_abnormal_eye_electrophysiolog1.49958566
39MP0001485_abnormal_pinna_reflex1.47994644
40MP0004811_abnormal_neuron_physiology1.47577728
41MP0002229_neurodegeneration1.44401839
42MP0001502_abnormal_circadian_rhythm1.43975231
43MP0001440_abnormal_grooming_behavior1.40298550
44MP0002882_abnormal_neuron_morphology1.38100063
45MP0000955_abnormal_spinal_cord1.38071366
46MP0002735_abnormal_chemical_nociception1.36118699
47MP0002909_abnormal_adrenal_gland1.29569249
48MP0003137_abnormal_impulse_conducting1.28888128
49MP0001970_abnormal_pain_threshold1.28541993
50MP0004858_abnormal_nervous_system1.28520351
51MP0002163_abnormal_gland_morphology1.26848574
52MP0005499_abnormal_olfactory_system1.25587868
53MP0005394_taste/olfaction_phenotype1.25587868
54MP0000631_abnormal_neuroendocrine_gland1.24450163
55MP0002066_abnormal_motor_capabilities/c1.22425403
56MP0003633_abnormal_nervous_system1.20445846
57MP0008569_lethality_at_weaning1.17193196
58MP0001501_abnormal_sleep_pattern1.16963904
59MP0000026_abnormal_inner_ear1.15930094
60MP0005167_abnormal_blood-brain_barrier1.15898789
61MP0004142_abnormal_muscle_tone1.14968026
62MP0008789_abnormal_olfactory_epithelium1.13805487
63MP0002733_abnormal_thermal_nociception1.13046111
64MP0001986_abnormal_taste_sensitivity1.12335487
65MP0003183_abnormal_peptide_metabolism1.11574137
66MP0001963_abnormal_hearing_physiology1.10059688
67MP0001905_abnormal_dopamine_level1.08177840
68MP0002752_abnormal_somatic_nervous1.06746205
69MP0005379_endocrine/exocrine_gland_phen1.05063638
70MP0002822_catalepsy1.04362823
71MP0003631_nervous_system_phenotype0.97958259
72MP0004924_abnormal_behavior0.96190755
73MP0005386_behavior/neurological_phenoty0.96190755
74MP0002152_abnormal_brain_morphology0.94911671
75MP0003329_amyloid_beta_deposits0.93897690
76MP0001727_abnormal_embryo_implantation0.85871516
77MP0005253_abnormal_eye_physiology0.83000848
78MP0003938_abnormal_ear_development0.81804724
79MP0002102_abnormal_ear_morphology0.81252200
80MP0003634_abnormal_glial_cell0.81038240
81MP0000681_abnormal_thyroid_gland0.80309467
82MP0004085_abnormal_heartbeat0.79271667
83MP0003632_abnormal_nervous_system0.78795296
84MP0001299_abnormal_eye_distance/0.78412030
85MP0001188_hyperpigmentation0.77928644
86MP0001944_abnormal_pancreas_morphology0.75064238
87MP0005535_abnormal_body_temperature0.73937024
88MP0003119_abnormal_digestive_system0.71500302
89MP0004133_heterotaxia0.70664366
90MP0005195_abnormal_posterior_eye0.70030281
91MP0002160_abnormal_reproductive_system0.69100361
92MP0003690_abnormal_glial_cell0.68925261
93MP0002069_abnormal_eating/drinking_beha0.67589159
94MP0005377_hearing/vestibular/ear_phenot0.63796810
95MP0003878_abnormal_ear_physiology0.63796810
96MP0000639_abnormal_adrenal_gland0.62747801
97MP0004019_abnormal_vitamin_homeostasis0.62338009
98MP0002090_abnormal_vision0.59634651
99MP0010386_abnormal_urinary_bladder0.58116573
100MP0002938_white_spotting0.56903099

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)4.81146484
2Focal motor seizures (HP:0011153)3.94455570
3Amyotrophic lateral sclerosis (HP:0007354)3.83398833
4Abnormality of the corticospinal tract (HP:0002492)3.62396280
5Hand muscle atrophy (HP:0009130)3.55438459
6Abnormality of renal resorption (HP:0011038)3.27863321
7Abnormality of the lower motor neuron (HP:0002366)3.22828052
8Acute necrotizing encephalopathy (HP:0006965)3.17698122
9Limb dystonia (HP:0002451)3.16902574
10Cerebral hypomyelination (HP:0006808)3.15948813
11Polyphagia (HP:0002591)3.12561740
12Abnormal mitochondria in muscle tissue (HP:0008316)3.11971688
13Focal seizures (HP:0007359)3.10908776
14Obstructive sleep apnea (HP:0002870)3.08696846
15Abnormal eating behavior (HP:0100738)3.02734288
16Sleep apnea (HP:0010535)3.02644533
17Action tremor (HP:0002345)2.97902952
18Torticollis (HP:0000473)2.97341112
19Medial flaring of the eyebrow (HP:0010747)2.93738359
20Thrombocytosis (HP:0001894)2.93608237
21Spastic gait (HP:0002064)2.91890018
22Septo-optic dysplasia (HP:0100842)2.88716525
23Epileptic encephalopathy (HP:0200134)2.79678681
24Papilledema (HP:0001085)2.78285695
25Broad-based gait (HP:0002136)2.77788846
26Febrile seizures (HP:0002373)2.77256429
27Diplopia (HP:0000651)2.73892684
28Abnormality of binocular vision (HP:0011514)2.73892684
29Tetraplegia (HP:0002445)2.68699295
30Acute encephalopathy (HP:0006846)2.67945389
31Progressive macrocephaly (HP:0004481)2.67160664
32Fetal akinesia sequence (HP:0001989)2.65245999
33Focal dystonia (HP:0004373)2.65073938
34Gait imbalance (HP:0002141)2.64398121
35Renal Fanconi syndrome (HP:0001994)2.63995326
36Nephronophthisis (HP:0000090)2.61117646
37Delusions (HP:0000746)2.60066325
38Mitochondrial inheritance (HP:0001427)2.57950033
39Distal upper limb amyotrophy (HP:0007149)2.55893470
40Upper limb amyotrophy (HP:0009129)2.55893470
41Diminished motivation (HP:0000745)2.44985721
42CNS hypomyelination (HP:0003429)2.43375994
43Progressive cerebellar ataxia (HP:0002073)2.41581544
44Abnormality of the renal medulla (HP:0100957)2.39859495
45Craniofacial dystonia (HP:0012179)2.39671102
46Intention tremor (HP:0002080)2.38903946
47Nephrogenic diabetes insipidus (HP:0009806)2.35748079
48Supranuclear gaze palsy (HP:0000605)2.33831250
49Generalized tonic-clonic seizures (HP:0002069)2.32825295
50Metaphyseal dysplasia (HP:0100255)2.30116635
51Impaired vibration sensation in the lower limbs (HP:0002166)2.29409380
52Abnormality of liposaccharide metabolism (HP:0010968)2.28376232
53Abnormality of glycosphingolipid metabolism (HP:0004343)2.28376232
54Abnormality of glycolipid metabolism (HP:0010969)2.28376232
55Postural instability (HP:0002172)2.28226093
56Congenital primary aphakia (HP:0007707)2.27511300
57Constricted visual fields (HP:0001133)2.25878200
58Mutism (HP:0002300)2.25551727
59Apathy (HP:0000741)2.23246306
60Hepatocellular necrosis (HP:0001404)2.19363839
61Drooling (HP:0002307)2.18846112
62Achilles tendon contracture (HP:0001771)2.15562367
63Hyperphosphatemia (HP:0002905)2.15316896
64Atonic seizures (HP:0010819)2.12435301
65Long foot (HP:0001833)2.11664419
66Visual hallucinations (HP:0002367)2.10938622
67Lipid accumulation in hepatocytes (HP:0006561)2.08575302
68Growth hormone deficiency (HP:0000824)2.07890085
69Hepatic necrosis (HP:0002605)2.07572407
70Increased hepatocellular lipid droplets (HP:0006565)2.05564849
71Hepatoblastoma (HP:0002884)2.04642287
72Poor coordination (HP:0002370)2.04491431
73Opisthotonus (HP:0002179)2.02735611
74Excessive salivation (HP:0003781)2.01164788
75Akinesia (HP:0002304)2.00436145
76Status epilepticus (HP:0002133)1.98525269
77Specific learning disability (HP:0001328)1.98342621
78Spastic tetraplegia (HP:0002510)1.97945666
79Prolonged QT interval (HP:0001657)1.93563860
80Increased intramyocellular lipid droplets (HP:0012240)1.91842855
81Glycosuria (HP:0003076)1.91269784
82Abnormality of urine glucose concentration (HP:0011016)1.91269784
83Morphological abnormality of the pyramidal tract (HP:0002062)1.90997939
84Proximal tubulopathy (HP:0000114)1.90427089
85Hemiparesis (HP:0001269)1.90127308
86Abnormality of midbrain morphology (HP:0002418)1.89762999
87Molar tooth sign on MRI (HP:0002419)1.89762999
88Thyroid-stimulating hormone excess (HP:0002925)1.85596990
89Biconcave vertebral bodies (HP:0004586)1.85224547
90Spastic tetraparesis (HP:0001285)1.84321107
91Leukodystrophy (HP:0002415)1.84220548
92Maternal diabetes (HP:0009800)1.83348092
93Cerebral edema (HP:0002181)1.82485253
94Abnormality of the Achilles tendon (HP:0005109)1.82108258
95Hyperthyroidism (HP:0000836)1.82073768
96Genetic anticipation (HP:0003743)1.82055022
97Abnormality of the aortic arch (HP:0012303)1.81751327
98Optic nerve hypoplasia (HP:0000609)1.81658110
99Increased muscle lipid content (HP:0009058)1.81355397
100Dialeptic seizures (HP:0011146)1.80654013

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WNK37.52951574
2PRKD34.99538991
3UHMK14.36367656
4DAPK23.31476507
5MARK12.96543364
6EPHA42.80325725
7NTRK32.74884560
8MAP3K42.34519581
9TESK12.03480198
10NTRK21.77039264
11PRKCH1.75135623
12LIMK11.74887339
13MAPK131.71901999
14BCKDK1.64179672
15MAP2K71.51653642
16PRKCG1.50894626
17ARAF1.49188376
18SGK4941.48379489
19SGK2231.48379489
20MARK21.41613716
21MINK11.32120205
22DAPK11.24440829
23CAMK2D1.23335787
24TAOK31.21970992
25ACVR1B1.21305950
26PLK21.15083224
27SGK21.14726153
28PHKG21.12580636
29PHKG11.12580636
30BMPR1B1.11118468
31CDK51.08610218
32CDC71.06101870
33MAP2K41.04599229
34LATS21.04014238
35CDK191.00290539
36PAK60.99389829
37GRK50.93160412
38SGK30.91694989
39DYRK1B0.90890909
40DYRK20.90166860
41GRK10.88768965
42PINK10.86787167
43CAMK2A0.86357318
44CAMK2B0.84422819
45FGFR20.82652558
46NTRK10.82345533
47RPS6KA20.79561507
48MAPK120.75973561
49CAMK2G0.75747234
50TNK20.74661088
51DYRK30.74281733
52CAMK40.72983812
53PAK30.72890816
54MAPK150.71838055
55ADRBK20.71312812
56PRKD20.70918882
57PRKCZ0.69857470
58TYRO30.69669004
59DAPK30.69098908
60PIM20.68214584
61TESK20.67168524
62TGFBR10.59889881
63EIF2AK10.58035674
64CAMK10.57790646
65PRKCE0.56305117
66DYRK1A0.52315505
67SGK10.52126169
68CAMKK10.51218293
69CDK140.51169141
70DMPK0.50725716
71PRKCD0.50443962
72BRAF0.47687858
73MAP3K120.47214258
74CSNK1A10.46937456
75CDK150.44803651
76RPS6KA60.44681553
77RPS6KC10.44287214
78RPS6KL10.44287214
79PRKACA0.42944865
80CAMK1D0.42900562
81CDK180.40153481
82CDK11A0.39107235
83RPS6KA30.39014851
84TIE10.38693098
85MAP3K110.38664592
86PRKCA0.37527294
87MAP3K90.36409095
88ADRBK10.35781402
89CASK0.35687464
90CSNK1G20.35427591
91PRKAA10.33629534
92AKT20.32326298
93CCNB10.32127602
94GSK3A0.30119765
95INSRR0.28687039
96PRKCQ0.28344756
97ALK0.24648060
98PRKD10.23625188
99RPS6KB10.23035403
100ILK0.22983873

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.81845214
2Synaptic vesicle cycle_Homo sapiens_hsa047213.73099267
3Oxidative phosphorylation_Homo sapiens_hsa001902.98483598
4Parkinsons disease_Homo sapiens_hsa050122.79520427
5Insulin secretion_Homo sapiens_hsa049112.75780800
6GABAergic synapse_Homo sapiens_hsa047272.69253861
7Cardiac muscle contraction_Homo sapiens_hsa042602.39629029
8Glutamatergic synapse_Homo sapiens_hsa047242.29012346
9Dopaminergic synapse_Homo sapiens_hsa047282.25374686
10Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006042.24168097
11Alzheimers disease_Homo sapiens_hsa050102.18892304
12Collecting duct acid secretion_Homo sapiens_hsa049662.12832577
13Amphetamine addiction_Homo sapiens_hsa050312.09245488
14Circadian entrainment_Homo sapiens_hsa047132.04478979
15Morphine addiction_Homo sapiens_hsa050322.03464697
16Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050142.00971595
17Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.97104319
18Fatty acid biosynthesis_Homo sapiens_hsa000611.94418110
19Huntingtons disease_Homo sapiens_hsa050161.92567116
20Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.90472813
21Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.84807391
22Cocaine addiction_Homo sapiens_hsa050301.79432318
23Long-term potentiation_Homo sapiens_hsa047201.67716039
24Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.60682906
25Phototransduction_Homo sapiens_hsa047441.40372665
26Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.35366564
27Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.35093298
28Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.30606298
29Cholinergic synapse_Homo sapiens_hsa047251.29270107
30Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.29198433
31Glycosaminoglycan degradation_Homo sapiens_hsa005311.25790032
32Renin secretion_Homo sapiens_hsa049241.25769800
33Calcium signaling pathway_Homo sapiens_hsa040201.21730864
34Axon guidance_Homo sapiens_hsa043601.20165322
35Olfactory transduction_Homo sapiens_hsa047401.14366608
36Aldosterone synthesis and secretion_Homo sapiens_hsa049251.13655110
37Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.13512568
38Taste transduction_Homo sapiens_hsa047421.10431395
39Arginine biosynthesis_Homo sapiens_hsa002201.09730242
40Long-term depression_Homo sapiens_hsa047301.09400304
41Vibrio cholerae infection_Homo sapiens_hsa051101.03234334
42cAMP signaling pathway_Homo sapiens_hsa040241.02156175
43Serotonergic synapse_Homo sapiens_hsa047261.01706214
44Phenylalanine metabolism_Homo sapiens_hsa003601.00090103
45Arginine and proline metabolism_Homo sapiens_hsa003300.99993472
46Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.99772977
47Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.97519968
48RNA polymerase_Homo sapiens_hsa030200.93602650
49Oxytocin signaling pathway_Homo sapiens_hsa049210.91908342
50Gastric acid secretion_Homo sapiens_hsa049710.91250302
51Vitamin B6 metabolism_Homo sapiens_hsa007500.90814570
52Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.89605281
53Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.82753932
54Phosphatidylinositol signaling system_Homo sapiens_hsa040700.82247371
55Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.80977454
56Salivary secretion_Homo sapiens_hsa049700.80935925
57Ether lipid metabolism_Homo sapiens_hsa005650.72473780
58Fatty acid elongation_Homo sapiens_hsa000620.68693528
59Ribosome_Homo sapiens_hsa030100.67131751
60Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.64779774
61Peroxisome_Homo sapiens_hsa041460.64358686
62Wnt signaling pathway_Homo sapiens_hsa043100.61205621
63Tyrosine metabolism_Homo sapiens_hsa003500.61045183
64Glucagon signaling pathway_Homo sapiens_hsa049220.59978101
65Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.57395999
66Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.51897785
67Melanogenesis_Homo sapiens_hsa049160.50025826
68Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.49519655
69Histidine metabolism_Homo sapiens_hsa003400.48810703
70Fatty acid metabolism_Homo sapiens_hsa012120.48551548
71Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.46363838
72Dilated cardiomyopathy_Homo sapiens_hsa054140.45669154
73cGMP-PKG signaling pathway_Homo sapiens_hsa040220.43368421
74Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.40237171
75Ras signaling pathway_Homo sapiens_hsa040140.39944396
76Metabolic pathways_Homo sapiens_hsa011000.38886384
77Linoleic acid metabolism_Homo sapiens_hsa005910.38867583
78Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.38848592
79Steroid biosynthesis_Homo sapiens_hsa001000.38453976
80Alcoholism_Homo sapiens_hsa050340.36643394
81Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.35355049
82Maturity onset diabetes of the young_Homo sapiens_hsa049500.34854784
83SNARE interactions in vesicular transport_Homo sapiens_hsa041300.33238433
84Renin-angiotensin system_Homo sapiens_hsa046140.32075136
85Regulation of autophagy_Homo sapiens_hsa041400.31944428
86Pancreatic secretion_Homo sapiens_hsa049720.31661122
87AMPK signaling pathway_Homo sapiens_hsa041520.30786199
88Thyroid hormone signaling pathway_Homo sapiens_hsa049190.29604360
89Gap junction_Homo sapiens_hsa045400.28990034
90Oocyte meiosis_Homo sapiens_hsa041140.27357607
91Thyroid hormone synthesis_Homo sapiens_hsa049180.26513072
92Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.25415336
93alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.23760646
94Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.23734630
95Carbohydrate digestion and absorption_Homo sapiens_hsa049730.23557031
96Phospholipase D signaling pathway_Homo sapiens_hsa040720.23483042
97Ovarian steroidogenesis_Homo sapiens_hsa049130.22543933
98Vascular smooth muscle contraction_Homo sapiens_hsa042700.21911981
99Hippo signaling pathway_Homo sapiens_hsa043900.20927126
100VEGF signaling pathway_Homo sapiens_hsa043700.20234639

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »