

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | auditory receptor cell differentiation (GO:0042491) | 8.40580505 |
| 2 | cerebellar Purkinje cell layer development (GO:0021680) | 6.97960732 |
| 3 | central nervous system myelination (GO:0022010) | 5.78946107 |
| 4 | axon ensheathment in central nervous system (GO:0032291) | 5.78946107 |
| 5 | neuronal ion channel clustering (GO:0045161) | 5.44654056 |
| 6 | regulation of female receptivity (GO:0045924) | 4.94667779 |
| 7 | neuronal action potential propagation (GO:0019227) | 4.85718878 |
| 8 | synaptic vesicle maturation (GO:0016188) | 4.83694061 |
| 9 | glutamate secretion (GO:0014047) | 4.73080982 |
| 10 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 4.72138611 |
| 11 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 4.70794200 |
| 12 | positive regulation of sodium ion transmembrane transporter activity (GO:2000651) | 4.64924600 |
| 13 | inner ear receptor cell differentiation (GO:0060113) | 4.55651430 |
| 14 | positive regulation of mitochondrial fission (GO:0090141) | 4.36606587 |
| 15 | response to dietary excess (GO:0002021) | 4.23023206 |
| 16 | female mating behavior (GO:0060180) | 4.10730788 |
| 17 | gamma-aminobutyric acid transport (GO:0015812) | 4.01398861 |
| 18 | synaptic transmission, glutamatergic (GO:0035249) | 3.89775742 |
| 19 | glyoxylate metabolic process (GO:0046487) | 3.89762210 |
| 20 | positive regulation of sodium ion transmembrane transport (GO:1902307) | 3.89669508 |
| 21 | dopamine biosynthetic process (GO:0042416) | 3.83950027 |
| 22 | hair cell differentiation (GO:0035315) | 3.81668293 |
| 23 | hypothalamus development (GO:0021854) | 3.75473125 |
| 24 | neurotransmitter secretion (GO:0007269) | 3.69277804 |
| 25 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.66559246 |
| 26 | behavioral response to nicotine (GO:0035095) | 3.65446326 |
| 27 | exploration behavior (GO:0035640) | 3.64412971 |
| 28 | glycerophospholipid catabolic process (GO:0046475) | 3.64102146 |
| 29 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 3.63952906 |
| 30 | locomotory exploration behavior (GO:0035641) | 3.63398303 |
| 31 | protein polyglutamylation (GO:0018095) | 3.60035279 |
| 32 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 3.59560109 |
| 33 | substrate-independent telencephalic tangential migration (GO:0021826) | 3.59560109 |
| 34 | neuron-neuron synaptic transmission (GO:0007270) | 3.48030893 |
| 35 | synaptic vesicle exocytosis (GO:0016079) | 3.41104401 |
| 36 | regulation of glutamate receptor signaling pathway (GO:1900449) | 3.40048853 |
| 37 | regulation of synaptic vesicle exocytosis (GO:2000300) | 3.38776375 |
| 38 | toxin metabolic process (GO:0009404) | 3.37889018 |
| 39 | mechanoreceptor differentiation (GO:0042490) | 3.36414824 |
| 40 | microtubule severing (GO:0051013) | 3.34992795 |
| 41 | regulation of neuronal synaptic plasticity (GO:0048168) | 3.34391730 |
| 42 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 3.29807830 |
| 43 | regulation of glutamate secretion (GO:0014048) | 3.25346651 |
| 44 | postsynaptic membrane organization (GO:0001941) | 3.23659480 |
| 45 | limb development (GO:0060173) | 3.20985420 |
| 46 | appendage development (GO:0048736) | 3.20985420 |
| 47 | negative regulation of amino acid transport (GO:0051956) | 3.16201496 |
| 48 | neuron cell-cell adhesion (GO:0007158) | 3.15449815 |
| 49 | pattern specification involved in kidney development (GO:0061004) | 3.14108034 |
| 50 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 3.12530608 |
| 51 | regulation of synaptic vesicle transport (GO:1902803) | 3.07967043 |
| 52 | establishment of mitochondrion localization (GO:0051654) | 3.07074525 |
| 53 | neuromuscular synaptic transmission (GO:0007274) | 3.03982992 |
| 54 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 3.02407831 |
| 55 | regulation of glycogen (starch) synthase activity (GO:2000465) | 3.02270780 |
| 56 | transmission of nerve impulse (GO:0019226) | 3.01765764 |
| 57 | regulation of mitochondrial fission (GO:0090140) | 3.01489315 |
| 58 | cell migration in hindbrain (GO:0021535) | 3.00361034 |
| 59 | positive regulation of neurotransmitter transport (GO:0051590) | 2.94142676 |
| 60 | presynaptic membrane organization (GO:0097090) | 2.94027955 |
| 61 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 2.93600729 |
| 62 | neurotransmitter transport (GO:0006836) | 2.92843084 |
| 63 | regulation of sodium ion transmembrane transporter activity (GO:2000649) | 2.92279447 |
| 64 | receptor recycling (GO:0001881) | 2.89673678 |
| 65 | astrocyte differentiation (GO:0048708) | 2.89501776 |
| 66 | detection of temperature stimulus (GO:0016048) | 2.89359554 |
| 67 | killing of cells in other organism involved in symbiotic interaction (GO:0051883) | 2.88853380 |
| 68 | disruption of cells of other organism involved in symbiotic interaction (GO:0051818) | 2.88853380 |
| 69 | synaptic vesicle endocytosis (GO:0048488) | 2.88287850 |
| 70 | positive regulation of sodium ion transport (GO:0010765) | 2.88184541 |
| 71 | detection of temperature stimulus involved in sensory perception (GO:0050961) | 2.88009751 |
| 72 | detection of temperature stimulus involved in sensory perception of pain (GO:0050965) | 2.88009751 |
| 73 | regulation of membrane repolarization (GO:0060306) | 2.87642607 |
| 74 | axonal fasciculation (GO:0007413) | 2.86026920 |
| 75 | behavioral response to ethanol (GO:0048149) | 2.85637151 |
| 76 | neurotransmitter-gated ion channel clustering (GO:0072578) | 2.83559040 |
| 77 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.83164261 |
| 78 | neuronal action potential (GO:0019228) | 2.82895652 |
| 79 | regulation of neurotransmitter levels (GO:0001505) | 2.82394753 |
| 80 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 2.82351277 |
| 81 | positive regulation of neurotransmitter secretion (GO:0001956) | 2.81760704 |
| 82 | regulation of voltage-gated calcium channel activity (GO:1901385) | 2.78749924 |
| 83 | regulation of neurotransmitter secretion (GO:0046928) | 2.77929633 |
| 84 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 2.77223527 |
| 85 | urinary tract smooth muscle contraction (GO:0014848) | 2.77050777 |
| 86 | synapse organization (GO:0050808) | 2.76879098 |
| 87 | behavioral defense response (GO:0002209) | 2.76525161 |
| 88 | behavioral fear response (GO:0001662) | 2.76525161 |
| 89 | phosphorylated carbohydrate dephosphorylation (GO:0046838) | 2.75316185 |
| 90 | inositol phosphate dephosphorylation (GO:0046855) | 2.75316185 |
| 91 | regulation of cAMP-dependent protein kinase activity (GO:2000479) | 2.75278922 |
| 92 | ATP synthesis coupled proton transport (GO:0015986) | 2.71968240 |
| 93 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.71968240 |
| 94 | regulation of synapse structural plasticity (GO:0051823) | 2.71006890 |
| 95 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.68370607 |
| 96 | neuron recognition (GO:0008038) | 2.67803186 |
| 97 | regulation of sodium ion transmembrane transport (GO:1902305) | 2.67096548 |
| 98 | cerebral cortex radially oriented cell migration (GO:0021799) | 2.66461243 |
| 99 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 2.66017222 |
| 100 | ATP hydrolysis coupled proton transport (GO:0015991) | 2.66017222 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 6.32379246 |
| 2 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 4.44318864 |
| 3 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 3.78925199 |
| 4 | REST_21632747_ChIP-Seq_MESCs_Mouse | 3.07283592 |
| 5 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.96192803 |
| 6 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.89772674 |
| 7 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.64758814 |
| 8 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.60922148 |
| 9 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 2.58326687 |
| 10 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.55289360 |
| 11 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.53996024 |
| 12 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.52919089 |
| 13 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.50792123 |
| 14 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.43854877 |
| 15 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.39358327 |
| 16 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.39102847 |
| 17 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.36146592 |
| 18 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.36146592 |
| 19 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 2.29906560 |
| 20 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.28562700 |
| 21 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.21616390 |
| 22 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.16413150 |
| 23 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 2.10008955 |
| 24 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.06265204 |
| 25 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.02536963 |
| 26 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.94335229 |
| 27 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.87395949 |
| 28 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.84876325 |
| 29 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.83154904 |
| 30 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.80226748 |
| 31 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.78024440 |
| 32 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.75104787 |
| 33 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.73317440 |
| 34 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.69688831 |
| 35 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.63116033 |
| 36 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.53825245 |
| 37 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.49748843 |
| 38 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.46422552 |
| 39 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.45470807 |
| 40 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.43989874 |
| 41 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.41466280 |
| 42 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.38399856 |
| 43 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 1.34778285 |
| 44 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.29275256 |
| 45 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.26614677 |
| 46 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.22949745 |
| 47 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.20826876 |
| 48 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.18392809 |
| 49 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.18278283 |
| 50 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.18275060 |
| 51 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.17470454 |
| 52 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.17048060 |
| 53 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.14327912 |
| 54 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.13523159 |
| 55 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.12668057 |
| 56 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.12462384 |
| 57 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.11684120 |
| 58 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.11684120 |
| 59 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.11564314 |
| 60 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.10188270 |
| 61 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.08914061 |
| 62 | P300_19829295_ChIP-Seq_ESCs_Human | 1.07826574 |
| 63 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.05131933 |
| 64 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.03460677 |
| 65 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 0.97250048 |
| 66 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 0.95614094 |
| 67 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.95479313 |
| 68 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.94651756 |
| 69 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.93049744 |
| 70 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.90921985 |
| 71 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.90469851 |
| 72 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 0.89644636 |
| 73 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.89429501 |
| 74 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 0.88904610 |
| 75 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.88513642 |
| 76 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 0.88111256 |
| 77 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.87099778 |
| 78 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 0.86263162 |
| 79 | ZNF274_21170338_ChIP-Seq_K562_Hela | 0.85244761 |
| 80 | REST_19997604_ChIP-ChIP_NEURONS_Mouse | 0.83051059 |
| 81 | TCF4_23295773_ChIP-Seq_U87_Human | 0.82798810 |
| 82 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 0.82651130 |
| 83 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.81952108 |
| 84 | SOX9_26525672_Chip-Seq_HEART_Mouse | 0.81699368 |
| 85 | TBX3_20139965_ChIP-Seq_MESCs_Mouse | 0.80254824 |
| 86 | TBX3_20139965_ChIP-Seq_ESCs_Mouse | 0.79861704 |
| 87 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.79499073 |
| 88 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.79376489 |
| 89 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.76094732 |
| 90 | AR_19668381_ChIP-Seq_PC3_Human | 0.75891334 |
| 91 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.75865823 |
| 92 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 0.75413211 |
| 93 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.75101549 |
| 94 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.74868492 |
| 95 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.73420938 |
| 96 | STAT3_23295773_ChIP-Seq_U87_Human | 0.73388131 |
| 97 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 0.72824402 |
| 98 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.72706103 |
| 99 | EWS_26573619_Chip-Seq_HEK293_Human | 0.72391355 |
| 100 | MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 0.71304593 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003880_abnormal_central_pattern | 4.06957564 |
| 2 | MP0004859_abnormal_synaptic_plasticity | 4.05580643 |
| 3 | MP0005423_abnormal_somatic_nervous | 3.89637883 |
| 4 | MP0003787_abnormal_imprinting | 3.78668501 |
| 5 | MP0009780_abnormal_chondrocyte_physiolo | 3.34978098 |
| 6 | MP0009046_muscle_twitch | 3.05995781 |
| 7 | MP0001968_abnormal_touch/_nociception | 2.75308594 |
| 8 | MP0003879_abnormal_hair_cell | 2.73268374 |
| 9 | MP0002064_seizures | 2.72929350 |
| 10 | MP0002736_abnormal_nociception_after | 2.69705544 |
| 11 | MP0003635_abnormal_synaptic_transmissio | 2.63387534 |
| 12 | MP0009745_abnormal_behavioral_response | 2.61677378 |
| 13 | MP0002063_abnormal_learning/memory/cond | 2.54816454 |
| 14 | MP0002272_abnormal_nervous_system | 2.54064171 |
| 15 | MP0003122_maternal_imprinting | 2.37832251 |
| 16 | MP0004270_analgesia | 2.37293019 |
| 17 | MP0002572_abnormal_emotion/affect_behav | 2.16591831 |
| 18 | MP0002876_abnormal_thyroid_physiology | 2.14194570 |
| 19 | MP0005645_abnormal_hypothalamus_physiol | 2.12266856 |
| 20 | MP0006276_abnormal_autonomic_nervous | 2.09233344 |
| 21 | MP0002734_abnormal_mechanical_nocicepti | 2.09188617 |
| 22 | MP0003123_paternal_imprinting | 2.08981067 |
| 23 | MP0005646_abnormal_pituitary_gland | 1.98448888 |
| 24 | MP0004885_abnormal_endolymph | 1.93207504 |
| 25 | MP0004145_abnormal_muscle_electrophysio | 1.91860466 |
| 26 | MP0001486_abnormal_startle_reflex | 1.89332475 |
| 27 | MP0000778_abnormal_nervous_system | 1.88038058 |
| 28 | MP0002837_dystrophic_cardiac_calcinosis | 1.81559353 |
| 29 | MP0003121_genomic_imprinting | 1.80024266 |
| 30 | MP0004147_increased_porphyrin_level | 1.75220398 |
| 31 | MP0001984_abnormal_olfaction | 1.72379056 |
| 32 | MP0003646_muscle_fatigue | 1.65647207 |
| 33 | MP0002067_abnormal_sensory_capabilities | 1.65598158 |
| 34 | MP0001529_abnormal_vocalization | 1.62823948 |
| 35 | MP0004742_abnormal_vestibular_system | 1.54133628 |
| 36 | MP0002557_abnormal_social/conspecific_i | 1.53496325 |
| 37 | MP0002184_abnormal_innervation | 1.53082155 |
| 38 | MP0005551_abnormal_eye_electrophysiolog | 1.49958566 |
| 39 | MP0001485_abnormal_pinna_reflex | 1.47994644 |
| 40 | MP0004811_abnormal_neuron_physiology | 1.47577728 |
| 41 | MP0002229_neurodegeneration | 1.44401839 |
| 42 | MP0001502_abnormal_circadian_rhythm | 1.43975231 |
| 43 | MP0001440_abnormal_grooming_behavior | 1.40298550 |
| 44 | MP0002882_abnormal_neuron_morphology | 1.38100063 |
| 45 | MP0000955_abnormal_spinal_cord | 1.38071366 |
| 46 | MP0002735_abnormal_chemical_nociception | 1.36118699 |
| 47 | MP0002909_abnormal_adrenal_gland | 1.29569249 |
| 48 | MP0003137_abnormal_impulse_conducting | 1.28888128 |
| 49 | MP0001970_abnormal_pain_threshold | 1.28541993 |
| 50 | MP0004858_abnormal_nervous_system | 1.28520351 |
| 51 | MP0002163_abnormal_gland_morphology | 1.26848574 |
| 52 | MP0005499_abnormal_olfactory_system | 1.25587868 |
| 53 | MP0005394_taste/olfaction_phenotype | 1.25587868 |
| 54 | MP0000631_abnormal_neuroendocrine_gland | 1.24450163 |
| 55 | MP0002066_abnormal_motor_capabilities/c | 1.22425403 |
| 56 | MP0003633_abnormal_nervous_system | 1.20445846 |
| 57 | MP0008569_lethality_at_weaning | 1.17193196 |
| 58 | MP0001501_abnormal_sleep_pattern | 1.16963904 |
| 59 | MP0000026_abnormal_inner_ear | 1.15930094 |
| 60 | MP0005167_abnormal_blood-brain_barrier | 1.15898789 |
| 61 | MP0004142_abnormal_muscle_tone | 1.14968026 |
| 62 | MP0008789_abnormal_olfactory_epithelium | 1.13805487 |
| 63 | MP0002733_abnormal_thermal_nociception | 1.13046111 |
| 64 | MP0001986_abnormal_taste_sensitivity | 1.12335487 |
| 65 | MP0003183_abnormal_peptide_metabolism | 1.11574137 |
| 66 | MP0001963_abnormal_hearing_physiology | 1.10059688 |
| 67 | MP0001905_abnormal_dopamine_level | 1.08177840 |
| 68 | MP0002752_abnormal_somatic_nervous | 1.06746205 |
| 69 | MP0005379_endocrine/exocrine_gland_phen | 1.05063638 |
| 70 | MP0002822_catalepsy | 1.04362823 |
| 71 | MP0003631_nervous_system_phenotype | 0.97958259 |
| 72 | MP0004924_abnormal_behavior | 0.96190755 |
| 73 | MP0005386_behavior/neurological_phenoty | 0.96190755 |
| 74 | MP0002152_abnormal_brain_morphology | 0.94911671 |
| 75 | MP0003329_amyloid_beta_deposits | 0.93897690 |
| 76 | MP0001727_abnormal_embryo_implantation | 0.85871516 |
| 77 | MP0005253_abnormal_eye_physiology | 0.83000848 |
| 78 | MP0003938_abnormal_ear_development | 0.81804724 |
| 79 | MP0002102_abnormal_ear_morphology | 0.81252200 |
| 80 | MP0003634_abnormal_glial_cell | 0.81038240 |
| 81 | MP0000681_abnormal_thyroid_gland | 0.80309467 |
| 82 | MP0004085_abnormal_heartbeat | 0.79271667 |
| 83 | MP0003632_abnormal_nervous_system | 0.78795296 |
| 84 | MP0001299_abnormal_eye_distance/ | 0.78412030 |
| 85 | MP0001188_hyperpigmentation | 0.77928644 |
| 86 | MP0001944_abnormal_pancreas_morphology | 0.75064238 |
| 87 | MP0005535_abnormal_body_temperature | 0.73937024 |
| 88 | MP0003119_abnormal_digestive_system | 0.71500302 |
| 89 | MP0004133_heterotaxia | 0.70664366 |
| 90 | MP0005195_abnormal_posterior_eye | 0.70030281 |
| 91 | MP0002160_abnormal_reproductive_system | 0.69100361 |
| 92 | MP0003690_abnormal_glial_cell | 0.68925261 |
| 93 | MP0002069_abnormal_eating/drinking_beha | 0.67589159 |
| 94 | MP0005377_hearing/vestibular/ear_phenot | 0.63796810 |
| 95 | MP0003878_abnormal_ear_physiology | 0.63796810 |
| 96 | MP0000639_abnormal_adrenal_gland | 0.62747801 |
| 97 | MP0004019_abnormal_vitamin_homeostasis | 0.62338009 |
| 98 | MP0002090_abnormal_vision | 0.59634651 |
| 99 | MP0010386_abnormal_urinary_bladder | 0.58116573 |
| 100 | MP0002938_white_spotting | 0.56903099 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Myokymia (HP:0002411) | 4.81146484 |
| 2 | Focal motor seizures (HP:0011153) | 3.94455570 |
| 3 | Amyotrophic lateral sclerosis (HP:0007354) | 3.83398833 |
| 4 | Abnormality of the corticospinal tract (HP:0002492) | 3.62396280 |
| 5 | Hand muscle atrophy (HP:0009130) | 3.55438459 |
| 6 | Abnormality of renal resorption (HP:0011038) | 3.27863321 |
| 7 | Abnormality of the lower motor neuron (HP:0002366) | 3.22828052 |
| 8 | Acute necrotizing encephalopathy (HP:0006965) | 3.17698122 |
| 9 | Limb dystonia (HP:0002451) | 3.16902574 |
| 10 | Cerebral hypomyelination (HP:0006808) | 3.15948813 |
| 11 | Polyphagia (HP:0002591) | 3.12561740 |
| 12 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.11971688 |
| 13 | Focal seizures (HP:0007359) | 3.10908776 |
| 14 | Obstructive sleep apnea (HP:0002870) | 3.08696846 |
| 15 | Abnormal eating behavior (HP:0100738) | 3.02734288 |
| 16 | Sleep apnea (HP:0010535) | 3.02644533 |
| 17 | Action tremor (HP:0002345) | 2.97902952 |
| 18 | Torticollis (HP:0000473) | 2.97341112 |
| 19 | Medial flaring of the eyebrow (HP:0010747) | 2.93738359 |
| 20 | Thrombocytosis (HP:0001894) | 2.93608237 |
| 21 | Spastic gait (HP:0002064) | 2.91890018 |
| 22 | Septo-optic dysplasia (HP:0100842) | 2.88716525 |
| 23 | Epileptic encephalopathy (HP:0200134) | 2.79678681 |
| 24 | Papilledema (HP:0001085) | 2.78285695 |
| 25 | Broad-based gait (HP:0002136) | 2.77788846 |
| 26 | Febrile seizures (HP:0002373) | 2.77256429 |
| 27 | Diplopia (HP:0000651) | 2.73892684 |
| 28 | Abnormality of binocular vision (HP:0011514) | 2.73892684 |
| 29 | Tetraplegia (HP:0002445) | 2.68699295 |
| 30 | Acute encephalopathy (HP:0006846) | 2.67945389 |
| 31 | Progressive macrocephaly (HP:0004481) | 2.67160664 |
| 32 | Fetal akinesia sequence (HP:0001989) | 2.65245999 |
| 33 | Focal dystonia (HP:0004373) | 2.65073938 |
| 34 | Gait imbalance (HP:0002141) | 2.64398121 |
| 35 | Renal Fanconi syndrome (HP:0001994) | 2.63995326 |
| 36 | Nephronophthisis (HP:0000090) | 2.61117646 |
| 37 | Delusions (HP:0000746) | 2.60066325 |
| 38 | Mitochondrial inheritance (HP:0001427) | 2.57950033 |
| 39 | Distal upper limb amyotrophy (HP:0007149) | 2.55893470 |
| 40 | Upper limb amyotrophy (HP:0009129) | 2.55893470 |
| 41 | Diminished motivation (HP:0000745) | 2.44985721 |
| 42 | CNS hypomyelination (HP:0003429) | 2.43375994 |
| 43 | Progressive cerebellar ataxia (HP:0002073) | 2.41581544 |
| 44 | Abnormality of the renal medulla (HP:0100957) | 2.39859495 |
| 45 | Craniofacial dystonia (HP:0012179) | 2.39671102 |
| 46 | Intention tremor (HP:0002080) | 2.38903946 |
| 47 | Nephrogenic diabetes insipidus (HP:0009806) | 2.35748079 |
| 48 | Supranuclear gaze palsy (HP:0000605) | 2.33831250 |
| 49 | Generalized tonic-clonic seizures (HP:0002069) | 2.32825295 |
| 50 | Metaphyseal dysplasia (HP:0100255) | 2.30116635 |
| 51 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.29409380 |
| 52 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.28376232 |
| 53 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.28376232 |
| 54 | Abnormality of glycolipid metabolism (HP:0010969) | 2.28376232 |
| 55 | Postural instability (HP:0002172) | 2.28226093 |
| 56 | Congenital primary aphakia (HP:0007707) | 2.27511300 |
| 57 | Constricted visual fields (HP:0001133) | 2.25878200 |
| 58 | Mutism (HP:0002300) | 2.25551727 |
| 59 | Apathy (HP:0000741) | 2.23246306 |
| 60 | Hepatocellular necrosis (HP:0001404) | 2.19363839 |
| 61 | Drooling (HP:0002307) | 2.18846112 |
| 62 | Achilles tendon contracture (HP:0001771) | 2.15562367 |
| 63 | Hyperphosphatemia (HP:0002905) | 2.15316896 |
| 64 | Atonic seizures (HP:0010819) | 2.12435301 |
| 65 | Long foot (HP:0001833) | 2.11664419 |
| 66 | Visual hallucinations (HP:0002367) | 2.10938622 |
| 67 | Lipid accumulation in hepatocytes (HP:0006561) | 2.08575302 |
| 68 | Growth hormone deficiency (HP:0000824) | 2.07890085 |
| 69 | Hepatic necrosis (HP:0002605) | 2.07572407 |
| 70 | Increased hepatocellular lipid droplets (HP:0006565) | 2.05564849 |
| 71 | Hepatoblastoma (HP:0002884) | 2.04642287 |
| 72 | Poor coordination (HP:0002370) | 2.04491431 |
| 73 | Opisthotonus (HP:0002179) | 2.02735611 |
| 74 | Excessive salivation (HP:0003781) | 2.01164788 |
| 75 | Akinesia (HP:0002304) | 2.00436145 |
| 76 | Status epilepticus (HP:0002133) | 1.98525269 |
| 77 | Specific learning disability (HP:0001328) | 1.98342621 |
| 78 | Spastic tetraplegia (HP:0002510) | 1.97945666 |
| 79 | Prolonged QT interval (HP:0001657) | 1.93563860 |
| 80 | Increased intramyocellular lipid droplets (HP:0012240) | 1.91842855 |
| 81 | Glycosuria (HP:0003076) | 1.91269784 |
| 82 | Abnormality of urine glucose concentration (HP:0011016) | 1.91269784 |
| 83 | Morphological abnormality of the pyramidal tract (HP:0002062) | 1.90997939 |
| 84 | Proximal tubulopathy (HP:0000114) | 1.90427089 |
| 85 | Hemiparesis (HP:0001269) | 1.90127308 |
| 86 | Abnormality of midbrain morphology (HP:0002418) | 1.89762999 |
| 87 | Molar tooth sign on MRI (HP:0002419) | 1.89762999 |
| 88 | Thyroid-stimulating hormone excess (HP:0002925) | 1.85596990 |
| 89 | Biconcave vertebral bodies (HP:0004586) | 1.85224547 |
| 90 | Spastic tetraparesis (HP:0001285) | 1.84321107 |
| 91 | Leukodystrophy (HP:0002415) | 1.84220548 |
| 92 | Maternal diabetes (HP:0009800) | 1.83348092 |
| 93 | Cerebral edema (HP:0002181) | 1.82485253 |
| 94 | Abnormality of the Achilles tendon (HP:0005109) | 1.82108258 |
| 95 | Hyperthyroidism (HP:0000836) | 1.82073768 |
| 96 | Genetic anticipation (HP:0003743) | 1.82055022 |
| 97 | Abnormality of the aortic arch (HP:0012303) | 1.81751327 |
| 98 | Optic nerve hypoplasia (HP:0000609) | 1.81658110 |
| 99 | Increased muscle lipid content (HP:0009058) | 1.81355397 |
| 100 | Dialeptic seizures (HP:0011146) | 1.80654013 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | WNK3 | 7.52951574 |
| 2 | PRKD3 | 4.99538991 |
| 3 | UHMK1 | 4.36367656 |
| 4 | DAPK2 | 3.31476507 |
| 5 | MARK1 | 2.96543364 |
| 6 | EPHA4 | 2.80325725 |
| 7 | NTRK3 | 2.74884560 |
| 8 | MAP3K4 | 2.34519581 |
| 9 | TESK1 | 2.03480198 |
| 10 | NTRK2 | 1.77039264 |
| 11 | PRKCH | 1.75135623 |
| 12 | LIMK1 | 1.74887339 |
| 13 | MAPK13 | 1.71901999 |
| 14 | BCKDK | 1.64179672 |
| 15 | MAP2K7 | 1.51653642 |
| 16 | PRKCG | 1.50894626 |
| 17 | ARAF | 1.49188376 |
| 18 | SGK494 | 1.48379489 |
| 19 | SGK223 | 1.48379489 |
| 20 | MARK2 | 1.41613716 |
| 21 | MINK1 | 1.32120205 |
| 22 | DAPK1 | 1.24440829 |
| 23 | CAMK2D | 1.23335787 |
| 24 | TAOK3 | 1.21970992 |
| 25 | ACVR1B | 1.21305950 |
| 26 | PLK2 | 1.15083224 |
| 27 | SGK2 | 1.14726153 |
| 28 | PHKG2 | 1.12580636 |
| 29 | PHKG1 | 1.12580636 |
| 30 | BMPR1B | 1.11118468 |
| 31 | CDK5 | 1.08610218 |
| 32 | CDC7 | 1.06101870 |
| 33 | MAP2K4 | 1.04599229 |
| 34 | LATS2 | 1.04014238 |
| 35 | CDK19 | 1.00290539 |
| 36 | PAK6 | 0.99389829 |
| 37 | GRK5 | 0.93160412 |
| 38 | SGK3 | 0.91694989 |
| 39 | DYRK1B | 0.90890909 |
| 40 | DYRK2 | 0.90166860 |
| 41 | GRK1 | 0.88768965 |
| 42 | PINK1 | 0.86787167 |
| 43 | CAMK2A | 0.86357318 |
| 44 | CAMK2B | 0.84422819 |
| 45 | FGFR2 | 0.82652558 |
| 46 | NTRK1 | 0.82345533 |
| 47 | RPS6KA2 | 0.79561507 |
| 48 | MAPK12 | 0.75973561 |
| 49 | CAMK2G | 0.75747234 |
| 50 | TNK2 | 0.74661088 |
| 51 | DYRK3 | 0.74281733 |
| 52 | CAMK4 | 0.72983812 |
| 53 | PAK3 | 0.72890816 |
| 54 | MAPK15 | 0.71838055 |
| 55 | ADRBK2 | 0.71312812 |
| 56 | PRKD2 | 0.70918882 |
| 57 | PRKCZ | 0.69857470 |
| 58 | TYRO3 | 0.69669004 |
| 59 | DAPK3 | 0.69098908 |
| 60 | PIM2 | 0.68214584 |
| 61 | TESK2 | 0.67168524 |
| 62 | TGFBR1 | 0.59889881 |
| 63 | EIF2AK1 | 0.58035674 |
| 64 | CAMK1 | 0.57790646 |
| 65 | PRKCE | 0.56305117 |
| 66 | DYRK1A | 0.52315505 |
| 67 | SGK1 | 0.52126169 |
| 68 | CAMKK1 | 0.51218293 |
| 69 | CDK14 | 0.51169141 |
| 70 | DMPK | 0.50725716 |
| 71 | PRKCD | 0.50443962 |
| 72 | BRAF | 0.47687858 |
| 73 | MAP3K12 | 0.47214258 |
| 74 | CSNK1A1 | 0.46937456 |
| 75 | CDK15 | 0.44803651 |
| 76 | RPS6KA6 | 0.44681553 |
| 77 | RPS6KC1 | 0.44287214 |
| 78 | RPS6KL1 | 0.44287214 |
| 79 | PRKACA | 0.42944865 |
| 80 | CAMK1D | 0.42900562 |
| 81 | CDK18 | 0.40153481 |
| 82 | CDK11A | 0.39107235 |
| 83 | RPS6KA3 | 0.39014851 |
| 84 | TIE1 | 0.38693098 |
| 85 | MAP3K11 | 0.38664592 |
| 86 | PRKCA | 0.37527294 |
| 87 | MAP3K9 | 0.36409095 |
| 88 | ADRBK1 | 0.35781402 |
| 89 | CASK | 0.35687464 |
| 90 | CSNK1G2 | 0.35427591 |
| 91 | PRKAA1 | 0.33629534 |
| 92 | AKT2 | 0.32326298 |
| 93 | CCNB1 | 0.32127602 |
| 94 | GSK3A | 0.30119765 |
| 95 | INSRR | 0.28687039 |
| 96 | PRKCQ | 0.28344756 |
| 97 | ALK | 0.24648060 |
| 98 | PRKD1 | 0.23625188 |
| 99 | RPS6KB1 | 0.23035403 |
| 100 | ILK | 0.22983873 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Nicotine addiction_Homo sapiens_hsa05033 | 3.81845214 |
| 2 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 3.73099267 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.98483598 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 2.79520427 |
| 5 | Insulin secretion_Homo sapiens_hsa04911 | 2.75780800 |
| 6 | GABAergic synapse_Homo sapiens_hsa04727 | 2.69253861 |
| 7 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.39629029 |
| 8 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.29012346 |
| 9 | Dopaminergic synapse_Homo sapiens_hsa04728 | 2.25374686 |
| 10 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 2.24168097 |
| 11 | Alzheimers disease_Homo sapiens_hsa05010 | 2.18892304 |
| 12 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.12832577 |
| 13 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.09245488 |
| 14 | Circadian entrainment_Homo sapiens_hsa04713 | 2.04478979 |
| 15 | Morphine addiction_Homo sapiens_hsa05032 | 2.03464697 |
| 16 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 2.00971595 |
| 17 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.97104319 |
| 18 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.94418110 |
| 19 | Huntingtons disease_Homo sapiens_hsa05016 | 1.92567116 |
| 20 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.90472813 |
| 21 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.84807391 |
| 22 | Cocaine addiction_Homo sapiens_hsa05030 | 1.79432318 |
| 23 | Long-term potentiation_Homo sapiens_hsa04720 | 1.67716039 |
| 24 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.60682906 |
| 25 | Phototransduction_Homo sapiens_hsa04744 | 1.40372665 |
| 26 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.35366564 |
| 27 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.35093298 |
| 28 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.30606298 |
| 29 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.29270107 |
| 30 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.29198433 |
| 31 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.25790032 |
| 32 | Renin secretion_Homo sapiens_hsa04924 | 1.25769800 |
| 33 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.21730864 |
| 34 | Axon guidance_Homo sapiens_hsa04360 | 1.20165322 |
| 35 | Olfactory transduction_Homo sapiens_hsa04740 | 1.14366608 |
| 36 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.13655110 |
| 37 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.13512568 |
| 38 | Taste transduction_Homo sapiens_hsa04742 | 1.10431395 |
| 39 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.09730242 |
| 40 | Long-term depression_Homo sapiens_hsa04730 | 1.09400304 |
| 41 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.03234334 |
| 42 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.02156175 |
| 43 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.01706214 |
| 44 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.00090103 |
| 45 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.99993472 |
| 46 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.99772977 |
| 47 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.97519968 |
| 48 | RNA polymerase_Homo sapiens_hsa03020 | 0.93602650 |
| 49 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.91908342 |
| 50 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.91250302 |
| 51 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.90814570 |
| 52 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.89605281 |
| 53 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.82753932 |
| 54 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.82247371 |
| 55 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.80977454 |
| 56 | Salivary secretion_Homo sapiens_hsa04970 | 0.80935925 |
| 57 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.72473780 |
| 58 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.68693528 |
| 59 | Ribosome_Homo sapiens_hsa03010 | 0.67131751 |
| 60 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.64779774 |
| 61 | Peroxisome_Homo sapiens_hsa04146 | 0.64358686 |
| 62 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.61205621 |
| 63 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.61045183 |
| 64 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.59978101 |
| 65 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.57395999 |
| 66 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.51897785 |
| 67 | Melanogenesis_Homo sapiens_hsa04916 | 0.50025826 |
| 68 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.49519655 |
| 69 | Histidine metabolism_Homo sapiens_hsa00340 | 0.48810703 |
| 70 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.48551548 |
| 71 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.46363838 |
| 72 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.45669154 |
| 73 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.43368421 |
| 74 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.40237171 |
| 75 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.39944396 |
| 76 | Metabolic pathways_Homo sapiens_hsa01100 | 0.38886384 |
| 77 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.38867583 |
| 78 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.38848592 |
| 79 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.38453976 |
| 80 | Alcoholism_Homo sapiens_hsa05034 | 0.36643394 |
| 81 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.35355049 |
| 82 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.34854784 |
| 83 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.33238433 |
| 84 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.32075136 |
| 85 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.31944428 |
| 86 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.31661122 |
| 87 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.30786199 |
| 88 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.29604360 |
| 89 | Gap junction_Homo sapiens_hsa04540 | 0.28990034 |
| 90 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.27357607 |
| 91 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.26513072 |
| 92 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.25415336 |
| 93 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.23760646 |
| 94 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.23734630 |
| 95 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.23557031 |
| 96 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.23483042 |
| 97 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.22543933 |
| 98 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.21911981 |
| 99 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.20927126 |
| 100 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.20234639 |

