OR7E156P

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1chromosome condensation (GO:0030261)9.83939447
2DNA packaging (GO:0006323)9.36046914
3sperm capacitation (GO:0048240)9.18563183
4plasma membrane fusion (GO:0045026)8.90346960
5microtubule depolymerization (GO:0007019)8.46205570
6single strand break repair (GO:0000012)8.45905264
7spermatid nucleus differentiation (GO:0007289)8.17535788
8spermatid development (GO:0007286)8.02738167
9sperm-egg recognition (GO:0035036)7.69449870
10binding of sperm to zona pellucida (GO:0007339)7.31356186
11microtubule polymerization or depolymerization (GO:0031109)6.91104834
12sexual reproduction (GO:0019953)6.89996722
13multicellular organism reproduction (GO:0032504)6.83714087
14rRNA methylation (GO:0031167)6.80567811
15calcium ion-dependent exocytosis (GO:0017156)6.70168767
16reproduction (GO:0000003)6.61439054
17negative regulation of inclusion body assembly (GO:0090084)6.61253583
18cell-cell recognition (GO:0009988)6.32451441
19protein polyglutamylation (GO:0018095)6.31950011
20protein targeting to Golgi (GO:0000042)6.21995792
21spermatogenesis (GO:0007283)6.18320235
22male gamete generation (GO:0048232)6.16256693
23phosphatidylethanolamine biosynthetic process (GO:0006646)6.00557395
24axonemal dynein complex assembly (GO:0070286)5.98575510
25establishment of protein localization to Golgi (GO:0072600)5.96503343
26antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.76752105
27retrograde transport, vesicle recycling within Golgi (GO:0000301)5.76174851
28rRNA modification (GO:0000154)5.75203773
29microtubule severing (GO:0051013)5.65071517
30gamete generation (GO:0007276)5.63659723
31centriole replication (GO:0007099)5.54629302
32phosphatidylethanolamine metabolic process (GO:0046337)5.54030983
33cellular ketone body metabolic process (GO:0046950)5.50150292
34positive regulation of Rab GTPase activity (GO:0032851)5.33766597
35regulation of Rab GTPase activity (GO:0032313)5.33766597
36motile cilium assembly (GO:0044458)4.90651960
37chromatin silencing (GO:0006342)4.85508420
38centriole assembly (GO:0098534)4.85313887
39ketone body metabolic process (GO:1902224)4.85168670
40germ cell development (GO:0007281)4.76125160
41single fertilization (GO:0007338)4.74648912
42regulation of inclusion body assembly (GO:0090083)4.72468647
43regulation of transcription involved in cell fate commitment (GO:0060850)4.71780954
44regulation of cilium movement (GO:0003352)4.67608225
45multicellular organismal reproductive process (GO:0048609)4.50984080
46cellular process involved in reproduction in multicellular organism (GO:0022412)4.49557078
47protein localization to Golgi apparatus (GO:0034067)4.48132211
48regulation of centriole replication (GO:0046599)4.47012261
49cell wall macromolecule catabolic process (GO:0016998)4.33435260
50coenzyme catabolic process (GO:0009109)4.30072238
51cilium or flagellum-dependent cell motility (GO:0001539)4.28794065
52RNA destabilization (GO:0050779)4.26773843
53cell wall macromolecule metabolic process (GO:0044036)4.20582843
54negative regulation of Rho protein signal transduction (GO:0035024)4.10811832
55nucleus organization (GO:0006997)4.09364516
56seminiferous tubule development (GO:0072520)4.06666793
57fertilization (GO:0009566)3.99457717
58glycerol ether metabolic process (GO:0006662)3.83995461
59epithelial cilium movement (GO:0003351)3.68774681
60multicellular organismal movement (GO:0050879)3.58140169
61musculoskeletal movement (GO:0050881)3.58140169
62organic cation transport (GO:0015695)3.55935746
63ether metabolic process (GO:0018904)3.53979039
64histone H3-K9 demethylation (GO:0033169)3.45519140
65cerebral cortex neuron differentiation (GO:0021895)3.44203798
66cartilage development involved in endochondral bone morphogenesis (GO:0060351)3.43195068
67negative regulation of gene expression, epigenetic (GO:0045814)3.32772931
68peptidyl-threonine dephosphorylation (GO:0035970)3.32621871
69regulation of somitogenesis (GO:0014807)3.31944433
70response to acidic pH (GO:0010447)3.31694965
71polyamine biosynthetic process (GO:0006596)3.30997457
72protein-DNA complex disassembly (GO:0032986)3.28734030
73nucleosome disassembly (GO:0006337)3.28734030
74mesenchymal cell differentiation involved in kidney development (GO:0072161)3.27981571
75mesenchymal cell differentiation involved in renal system development (GO:2001012)3.27981571
76regulation of microtubule-based movement (GO:0060632)3.26180333
77cilium movement (GO:0003341)3.25156002
78protein depolymerization (GO:0051261)3.22687122
79cell differentiation involved in metanephros development (GO:0072202)3.14442168
80regulation of interleukin-13 production (GO:0032656)3.12719136
81cellular response to pH (GO:0071467)3.10565290
82regulation of T-helper 2 cell differentiation (GO:0045628)3.09426998
83DNA conformation change (GO:0071103)3.08580673
84cranial nerve morphogenesis (GO:0021602)3.05686302
85microtubule nucleation (GO:0007020)3.04940580
86male meiosis I (GO:0007141)3.02829509
87cell recognition (GO:0008037)2.99497969
88glomerular visceral epithelial cell development (GO:0072015)2.99369822
89multicellular organismal development (GO:0007275)2.97191423
90NAD biosynthetic process (GO:0009435)2.96228428
91regulation of meiosis I (GO:0060631)2.95867827
92piRNA metabolic process (GO:0034587)2.92592260
93glomerular epithelial cell development (GO:0072310)2.91960027
94homeostasis of number of cells within a tissue (GO:0048873)2.91533441
95membrane protein intracellular domain proteolysis (GO:0031293)2.90754374
96male meiosis (GO:0007140)2.85173293
97acrosome reaction (GO:0007340)12.3986974
98fusion of sperm to egg plasma membrane (GO:0007342)11.7262372
99sperm motility (GO:0030317)11.3946752
100response to pheromone (GO:0019236)10.1652192

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.99299508
2MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human3.85069314
3SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.79519140
4TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.46665840
5POU5F1_26923725_Chip-Seq_MESODERM_Mouse2.46665840
6VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human2.25899278
7ELF1_20517297_ChIP-Seq_JURKAT_Human2.25725290
8CBP_20019798_ChIP-Seq_JUKART_Human2.19888431
9IRF4_20064451_ChIP-Seq_CD4+T_Mouse2.19888431
10CTBP2_25329375_ChIP-Seq_LNCAP_Human2.19342960
11ERA_21632823_ChIP-Seq_H3396_Human2.14279819
12CTBP1_25329375_ChIP-Seq_LNCAP_Human2.04748450
13RAC3_21632823_ChIP-Seq_H3396_Human1.98385376
14RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.96685810
15EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.96093767
16WDR5_24793694_ChIP-Seq_LNCAP_Human1.93956115
17EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.93167793
18NANOG_20526341_ChIP-Seq_ESCs_Human1.91403397
19CTCF_27219007_Chip-Seq_Bcells_Human1.83295451
20UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.78713373
21DROSHA_22980978_ChIP-Seq_HELA_Human1.76912781
22TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.75406811
23MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.75239141
24E2F1_20622854_ChIP-Seq_HELA_Human1.74650184
25EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.74467522
26BCL6_27268052_Chip-Seq_Bcells_Human1.74267318
27MYC_19829295_ChIP-Seq_ESCs_Human1.71398943
28STAT6_21828071_ChIP-Seq_BEAS2B_Human1.70543946
29YY1_22570637_ChIP-Seq_MALME-3M_Human1.69644132
30SMC4_20622854_ChIP-Seq_HELA_Human1.69344488
31TDRD3_21172665_ChIP-Seq_MCF-7_Human1.69057593
32TAF2_19829295_ChIP-Seq_ESCs_Human1.63726755
33PHF8_20622854_ChIP-Seq_HELA_Human1.62914868
34P68_20966046_ChIP-Seq_HELA_Human1.60642026
35EZH2_22144423_ChIP-Seq_EOC_Human1.60597222
36ER_23166858_ChIP-Seq_MCF-7_Human1.60112505
37AUTS2_25519132_ChIP-Seq_293T-REX_Human1.59097068
38CTCF_20526341_ChIP-Seq_ESCs_Human1.58795743
39BCOR_27268052_Chip-Seq_Bcells_Human1.57783058
40PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.52792884
41SMAD4_21741376_ChIP-Seq_EPCs_Human1.52556099
42OCT4_20526341_ChIP-Seq_ESCs_Human1.51546268
43TP63_22573176_ChIP-Seq_HFKS_Human1.51118596
44ETV2_25802403_ChIP-Seq_MESCs_Mouse1.43288182
45P300_27268052_Chip-Seq_Bcells_Human1.42617560
46SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.41866685
47* FUS_26573619_Chip-Seq_HEK293_Human1.41590480
48LXR_22292898_ChIP-Seq_THP-1_Human1.40647894
49TP53_18474530_ChIP-ChIP_U2OS_Human1.39963540
50SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.38347539
51HNFA_21074721_ChIP-Seq_CACO-2_Human1.38312475
52AR_25329375_ChIP-Seq_VCAP_Human1.37882607
53CBX2_22325352_ChIP-Seq_293T-Rex_Human1.36001646
54GATA3_21878914_ChIP-Seq_MCF-7_Human1.35772419
55SMAD3_21741376_ChIP-Seq_ESCs_Human1.35249663
56RBPJ_21746931_ChIP-Seq_IB4_Human1.33109264
57CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.32183510
58ERG_20517297_ChIP-Seq_VCAP_Human1.30855782
59* ARNT_22903824_ChIP-Seq_MCF-7_Human1.29677517
60SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.28908152
61ETV1_20927104_ChIP-Seq_GIST48_Human1.28611617
62SUZ12_27294783_Chip-Seq_ESCs_Mouse1.28073804
63SOX2_22085726_ChIP-Seq_NPCs_Mouse1.27584135
64P63_20808887_ChIP-Seq_KERATINOCYTES_Human1.25744165
65KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse1.23797867
66EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.22950583
67TP63_19390658_ChIP-ChIP_HaCaT_Human1.21729416
68ZNF274_21170338_ChIP-Seq_K562_Hela1.21610880
69TOP2B_26459242_ChIP-Seq_MCF-7_Human1.20792081
70KLF5_20875108_ChIP-Seq_MESCs_Mouse1.19969676
71RUNX1_26923725_Chip-Seq_HPCs_Mouse1.19703538
72RUNX_20019798_ChIP-Seq_JUKART_Human1.19443892
73NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.17420143
74NFYB_21822215_ChIP-Seq_K562_Human1.17318586
75PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.15912677
76* SMAD3_21741376_ChIP-Seq_EPCs_Human1.15407411
77ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.14922800
78SMAD4_21741376_ChIP-Seq_HESCs_Human1.14432696
79* CEBPB_22108803_ChIP-Seq_LS180_Human1.13328858
80TBL1_22424771_ChIP-Seq_293T_Human1.12917371
81SMRT_27268052_Chip-Seq_Bcells_Human1.12183834
82HOXB7_26014856_ChIP-Seq_BT474_Human1.12173736
83* P53_21459846_ChIP-Seq_SAOS-2_Human1.10467003
84RUNX2_22187159_ChIP-Seq_PCA_Human1.09763582
85PHF8_20622853_ChIP-Seq_HELA_Human1.09200739
86* P300_19829295_ChIP-Seq_ESCs_Human1.07224312
87EZH2_27294783_Chip-Seq_ESCs_Mouse1.06302143
88GATA6_21074721_ChIP-Seq_CACO-2_Human1.05969484
89NANOG_19829295_ChIP-Seq_ESCs_Human1.05260972
90SOX2_19829295_ChIP-Seq_ESCs_Human1.05260972
91E2F1_17053090_ChIP-ChIP_MCF-7_Human1.05133403
92* SA1_27219007_Chip-Seq_Bcells_Human1.04659216
93CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.02946684
94OCT1_27270436_Chip-Seq_PROSTATE_Human1.01527440
95FOXH1_21741376_ChIP-Seq_EPCs_Human0.99660289
96CSB_26484114_Chip-Seq_FIBROBLAST_Human0.98862831
97GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98675738
98PCGF4_22325352_ChIP-Seq_293T-Rex_Human0.98610283
99FOXH1_21741376_ChIP-Seq_ESCs_Human0.98360812
100GF1_26923725_Chip-Seq_HPCs_Mouse0.97057759

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005377_hearing/vestibular/ear_phenot4.92957698
2MP0003878_abnormal_ear_physiology4.92957698
3MP0003698_abnormal_male_reproductive4.56736157
4MP0005670_abnormal_white_adipose4.49349658
5MP0001929_abnormal_gametogenesis3.99685476
6MP0001348_abnormal_lacrimal_gland3.60214466
7MP0000678_abnormal_parathyroid_gland2.96712324
8MP0002161_abnormal_fertility/fecundity2.55375067
9MP0003011_delayed_dark_adaptation2.33906848
10MP0003718_maternal_effect2.24489118
11MP0002132_abnormal_respiratory_system2.21404629
12MP0005410_abnormal_fertilization12.4765699
13MP0003646_muscle_fatigue1.93625648
14MP0005379_endocrine/exocrine_gland_phen1.90258796
15MP0002210_abnormal_sex_determination1.84465846
16MP0002234_abnormal_pharynx_morphology1.79995222
17MP0002249_abnormal_larynx_morphology1.74484509
18MP0005423_abnormal_somatic_nervous1.65773298
19MP0004510_myositis1.63655343
20MP0001145_abnormal_male_reproductive1.54512391
21MP0009053_abnormal_anal_canal1.51490997
22MP0002282_abnormal_trachea_morphology1.48644295
23MP0000653_abnormal_sex_gland1.45980242
24MP0001486_abnormal_startle_reflex1.43805300
25MP0001485_abnormal_pinna_reflex1.40715422
26MP0005310_abnormal_salivary_gland1.29062118
27MP0002822_catalepsy1.29003750
28MP0002735_abnormal_chemical_nociception1.26148417
29MP0000534_abnormal_ureter_morphology1.22440253
30MP0004742_abnormal_vestibular_system1.19978417
31MP0002127_abnormal_cardiovascular_syste1.17603998
32MP0001968_abnormal_touch/_nociception1.17063663
33MP0001765_abnormal_ion_homeostasis1.14746923
34MP0004859_abnormal_synaptic_plasticity1.09551524
35MP0005248_abnormal_Harderian_gland1.06449562
36MP0001963_abnormal_hearing_physiology1.05640039
37MP0008877_abnormal_DNA_methylation0.99921794
38MP0005395_other_phenotype0.99313457
39MP0000681_abnormal_thyroid_gland0.98734952
40MP0002138_abnormal_hepatobiliary_system0.98121235
41MP0000026_abnormal_inner_ear0.97811581
42MP0000049_abnormal_middle_ear0.88337271
43MP0005451_abnormal_body_composition0.87291054
44MP0003879_abnormal_hair_cell0.86646150
45MP0001879_abnormal_lymphatic_vessel0.85890220
46MP0002229_neurodegeneration0.83947739
47MP0000955_abnormal_spinal_cord0.81741977
48MP0005367_renal/urinary_system_phenotyp0.75104159
49MP0000516_abnormal_urinary_system0.75104159
50MP0004085_abnormal_heartbeat0.74701662
51MP0002733_abnormal_thermal_nociception0.74630476
52MP0005666_abnormal_adipose_tissue0.70280692
53MP0002067_abnormal_sensory_capabilities0.69325020
54MP0005167_abnormal_blood-brain_barrier0.68976342
55MP0008569_lethality_at_weaning0.68633142
56MP0005551_abnormal_eye_electrophysiolog0.68099049
57MP0009115_abnormal_fat_cell0.64635404
58MP0005636_abnormal_mineral_homeostasis0.63833797
59MP0005375_adipose_tissue_phenotype0.63047509
60MP0003077_abnormal_cell_cycle0.60495551
61MP0001666_abnormal_nutrient_absorption0.58388288
62MP0001905_abnormal_dopamine_level0.57813725
63MP0004484_altered_response_of0.57385653
64MP0002557_abnormal_social/conspecific_i0.56654023
65MP0003119_abnormal_digestive_system0.56628749
66MP0005253_abnormal_eye_physiology0.54907380
67MP0000003_abnormal_adipose_tissue0.54846291
68MP0003936_abnormal_reproductive_system0.54191826
69MP0005083_abnormal_biliary_tract0.53978066
70MP0000566_synostosis0.53868340
71MP0004233_abnormal_muscle_weight0.53484244
72MP0005623_abnormal_meninges_morphology0.51973534
73MP0009697_abnormal_copulation0.51537900
74MP0002572_abnormal_emotion/affect_behav0.51127100
75MP0001970_abnormal_pain_threshold0.49579130
76MP0006292_abnormal_olfactory_placode0.48825461
77MP0008995_early_reproductive_senescence0.48775083
78MP0002734_abnormal_mechanical_nocicepti0.46918774
79MP0003880_abnormal_central_pattern0.46677897
80MP0002653_abnormal_ependyma_morphology0.46452899
81MP0003699_abnormal_female_reproductive0.46167743
82MP0002272_abnormal_nervous_system0.45927315
83MP0005535_abnormal_body_temperature0.45527895
84MP0003137_abnormal_impulse_conducting0.44031584
85MP0009745_abnormal_behavioral_response0.43354395
86MP0001440_abnormal_grooming_behavior0.43231248
87MP0000249_abnormal_blood_vessel0.41410781
88MP0004036_abnormal_muscle_relaxation0.40944488
89MP0000470_abnormal_stomach_morphology0.40651158
90MP0010368_abnormal_lymphatic_system0.36667182
91MP0001984_abnormal_olfaction0.36283522
92MP0005647_abnormal_sex_gland0.36186627
93MP0000467_abnormal_esophagus_morphology0.32890799
94MP0004957_abnormal_blastocyst_morpholog0.32027856
95MP0001501_abnormal_sleep_pattern0.31959501
96MP0000613_abnormal_salivary_gland0.31954108
97MP0002928_abnormal_bile_duct0.31853180
98MP0008961_abnormal_basal_metabolism0.30988331
99MP0005408_hypopigmentation0.30205946
100MP0002882_abnormal_neuron_morphology0.29801488

Predicted human phenotypes

RankGene SetZ-score
1Severe visual impairment (HP:0001141)8.62099651
2Dynein arm defect of respiratory motile cilia (HP:0012255)5.86930852
3Absent/shortened dynein arms (HP:0200106)5.86930852
4Asymmetric septal hypertrophy (HP:0001670)5.43557761
5Bony spicule pigmentary retinopathy (HP:0007737)5.13196241
6Attenuation of retinal blood vessels (HP:0007843)5.12948902
7Bell-shaped thorax (HP:0001591)4.75844118
8Resting tremor (HP:0002322)4.69037583
9Abnormal ciliary motility (HP:0012262)4.56260547
10Abnormal respiratory motile cilium physiology (HP:0012261)4.45458013
11Hypoplastic ischia (HP:0003175)4.43424120
12Parkinsonism with favorable response to dopaminergic medication (HP:0002548)4.29886392
13Abnormal rod and cone electroretinograms (HP:0008323)4.26734504
14Abnormal respiratory motile cilium morphology (HP:0005938)4.22273508
15Abnormal respiratory epithelium morphology (HP:0012253)4.22273508
16Tubulointerstitial nephritis (HP:0001970)4.18797554
17Enlarged epiphyses (HP:0010580)4.16123502
18Infertility (HP:0000789)4.14590181
19Male infertility (HP:0003251)4.08418822
20Nasal polyposis (HP:0100582)3.99498320
21Abnormality of macular pigmentation (HP:0008002)3.97556212
22Abnormality of the ischium (HP:0003174)3.92277683
23Potter facies (HP:0002009)3.89661580
24Facial shape deformation (HP:0011334)3.89661580
25Hyperkalemia (HP:0002153)3.88262040
26Chronic hepatic failure (HP:0100626)3.79286467
27Aplasia/Hypoplasia of the earlobes (HP:0009906)3.78846678
28Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.71913119
29Azoospermia (HP:0000027)3.70581466
30Abnormal spermatogenesis (HP:0008669)3.58635752
31Aplasia/Hypoplasia of the pubic bone (HP:0009104)3.48104262
32Impulsivity (HP:0100710)3.34614294
33Unilateral renal agenesis (HP:0000122)3.23611060
34Abnormality of the nasal mucosa (HP:0000433)3.21638732
35Cone-rod dystrophy (HP:0000548)3.20544515
36Congenital malformation of the right heart (HP:0011723)3.02372458
37Double outlet right ventricle (HP:0001719)3.02372458
38Postural instability (HP:0002172)2.93669842
39Hypoplasia of the thymus (HP:0000778)2.90405768
40Abnormality of the aortic arch (HP:0012303)2.85712054
41Abnormal urine output (HP:0012590)2.73758006
42Renal dysplasia (HP:0000110)2.72616850
43Abnormality of the costochondral junction (HP:0000919)2.70141021
44Generalized aminoaciduria (HP:0002909)2.69775481
45Osteomalacia (HP:0002749)2.65473695
46Nephronophthisis (HP:0000090)2.64203699
47Stage 5 chronic kidney disease (HP:0003774)2.58820927
48Progressive sensorineural hearing impairment (HP:0000408)2.58293796
49Rhinitis (HP:0012384)2.56078869
50Absent epiphyses (HP:0010577)2.44316123
51Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.44316123
52Epiphyseal dysplasia (HP:0002656)2.43796283
53Abnormality of renal excretion (HP:0011036)2.39170003
54Abnormality of potassium homeostasis (HP:0011042)2.37789726
55Amelogenesis imperfecta (HP:0000705)2.35908442
56Flattened epiphyses (HP:0003071)2.35497268
57Truncal obesity (HP:0001956)2.34953830
58Abnormality of the parathyroid morphology (HP:0011766)2.32133055
59Progressive cerebellar ataxia (HP:0002073)2.30853900
60Ventricular tachycardia (HP:0004756)2.29087774
61Hypoalphalipoproteinemia (HP:0003233)2.28173496
62Abnormality of dental color (HP:0011073)2.25575093
63Polydipsia (HP:0001959)2.24593304
64Abnormal drinking behavior (HP:0030082)2.24593304
65Aplasia/Hypoplasia of the sacrum (HP:0008517)2.18671863
66Portal hypertension (HP:0001409)2.17469606
67Abnormality of the renal medulla (HP:0100957)2.16980770
68Polyuria (HP:0000103)2.14383626
69Abnormality of the pubic bones (HP:0003172)2.14084268
70Abnormality of the epiphysis of the femoral head (HP:0010574)2.13704364
71Widely patent fontanelles and sutures (HP:0004492)2.11407434
72Hyponatremia (HP:0002902)2.09350284
73Short ribs (HP:0000773)2.02931154
74Tubulointerstitial abnormality (HP:0001969)2.02412439
75Tetany (HP:0001281)2.01235249
76Insulin-resistant diabetes mellitus (HP:0000831)2.00782468
77Sensory axonal neuropathy (HP:0003390)2.00280853
78Spastic paraparesis (HP:0002313)2.00199353
79Abnormality involving the epiphyses of the lower limbs (HP:0006500)1.99498464
80Abnormality of femoral epiphyses (HP:0006499)1.99498464
81Abnormality of the hepatic vasculature (HP:0006707)1.98316690
82Hypophosphatemic rickets (HP:0004912)1.96703317
83Bronchiectasis (HP:0002110)1.95692812
84Mixed hearing impairment (HP:0000410)1.94846707
85Atelectasis (HP:0100750)1.91749086
86Decreased central vision (HP:0007663)1.89387826
87Transposition of the great arteries (HP:0001669)1.88894160
88Abnormal connection of the cardiac segments (HP:0011545)1.88894160
89Abnormal ventriculo-arterial connection (HP:0011563)1.88894160
90Abnormality of the femoral head (HP:0003368)1.88567953
91Flat capital femoral epiphysis (HP:0003370)1.88279708
92Vertebral clefting (HP:0008428)1.88207562
93Recurrent corneal erosions (HP:0000495)1.88122407
94Hyperthyroidism (HP:0000836)1.87324901
95Renovascular hypertension (HP:0100817)1.83921336
96Intellectual disability, moderate (HP:0002342)1.82142322
97Focal segmental glomerulosclerosis (HP:0000097)1.82078514
98Menstrual irregularities (HP:0000858)1.81367943
99Renal Fanconi syndrome (HP:0001994)1.79798717
100Recurrent pneumonia (HP:0006532)1.79629524

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PLK48.55105139
2TESK16.35126692
3DDR25.40308427
4INSRR3.96531537
5MAP4K23.54516256
6PNCK3.16707780
7PLK23.03291031
8STK382.89115073
9BRD42.72634465
10MAPK152.32794422
11CAMK1G2.21661078
12STK38L2.17056333
13WNK12.02030572
14PRKD31.89285829
15PIK3CG1.68562105
16MST1R1.65147881
17PDPK11.49666047
18CDK71.42302887
19PDK11.38061200
20KSR21.31023231
21CDK121.25375317
22DYRK1B1.24480682
23PTK2B1.13234205
24MAP3K91.11109968
25NEK61.02781735
26LATS20.90649247
27MAP3K20.83554050
28BRAF0.82802525
29MAP3K110.80334186
30UHMK10.79164535
31CAMK1D0.75669392
32RPS6KA20.75239987
33PRKG20.74570917
34PRKG10.65425184
35AKT30.64803709
36RPS6KA10.64723393
37ACVR1B0.64534987
38PRKAA20.63123294
39MAP3K80.61426059
40WNK40.59681057
41MAP2K20.56172823
42STK390.54280456
43CDK40.53922997
44LATS10.53596007
45CAMK10.53561921
46TYRO30.50489484
47CDK30.49576595
48ROCK10.48909212
49MUSK0.47493736
50RPS6KC10.46056069
51RPS6KL10.46056069
52ARAF0.44599480
53PINK10.43315563
54RPS6KA60.42733812
55CDK20.42128166
56GSK3B0.41107477
57CDK190.39379918
58BMPR1B0.39316440
59CDK10.38682669
60MAPK10.38626464
61MAP3K10.38516348
62NTRK30.36891607
63CAMK40.35076894
64CHEK10.34353933
65SGK2230.34163665
66SGK4940.34163665
67PRKCG0.33699170
68SIK20.32371374
69MTOR0.31571653
70MAPK80.28671404
71BRSK10.27708323
72TESK20.26793654
73MARK10.26418615
74PRKCZ0.25515754
75TIE10.25492797
76SGK10.25482763
77MAP3K40.23613592
78MARK20.21663848
79MET0.21324699
80MAPK140.21039258
81PRKCB0.19598421
82DYRK30.18418443
83MAPK100.17480285
84PKN10.16410640
85MAPK110.15373026
86AKT10.15014795
87ZAK0.14649889
88OXSR10.13984364
89MAP3K130.13651037
90MAP3K70.12856687
91PRKACB0.07492370
92PRKACA0.07265599
93AURKA0.06380372
94FER0.06182043
95JAK30.05873052
96BLK0.05487642
97CDK11A0.05472903
98KIT0.05441687
99DYRK20.05304161
100PASK0.05015123

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000728.21185166
2Fatty acid biosynthesis_Homo sapiens_hsa000615.48700826
3Olfactory transduction_Homo sapiens_hsa047403.86793799
4Butanoate metabolism_Homo sapiens_hsa006502.72872735
5Allograft rejection_Homo sapiens_hsa053302.14063768
6Type I diabetes mellitus_Homo sapiens_hsa049402.08721885
7Dorso-ventral axis formation_Homo sapiens_hsa043202.07428342
8Autoimmune thyroid disease_Homo sapiens_hsa053202.06564018
9Glycerophospholipid metabolism_Homo sapiens_hsa005641.97803014
10Graft-versus-host disease_Homo sapiens_hsa053321.95640962
11Antigen processing and presentation_Homo sapiens_hsa046121.82627963
12Taste transduction_Homo sapiens_hsa047421.72499351
13Phenylalanine metabolism_Homo sapiens_hsa003601.67243867
14Type II diabetes mellitus_Homo sapiens_hsa049301.64819534
15RNA transport_Homo sapiens_hsa030131.62525012
16Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.61158874
17Fatty acid degradation_Homo sapiens_hsa000711.52935454
18Viral myocarditis_Homo sapiens_hsa054161.52614296
19Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.46099421
20Arginine and proline metabolism_Homo sapiens_hsa003301.41797245
21Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.33633762
22Fatty acid metabolism_Homo sapiens_hsa012121.31647071
23Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.25648835
24Endocytosis_Homo sapiens_hsa041441.22637421
25Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.21607626
26Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.18155642
27Protein digestion and absorption_Homo sapiens_hsa049741.14959187
28Oocyte meiosis_Homo sapiens_hsa041141.05936408
29Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.03770772
30Salivary secretion_Homo sapiens_hsa049700.97134854
31Arginine biosynthesis_Homo sapiens_hsa002200.96259881
32Phototransduction_Homo sapiens_hsa047440.95027433
33Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.94560903
34Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.92590770
35Inositol phosphate metabolism_Homo sapiens_hsa005620.91245967
36Adipocytokine signaling pathway_Homo sapiens_hsa049200.90533020
37Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.88993908
38Cardiac muscle contraction_Homo sapiens_hsa042600.87993458
39Synaptic vesicle cycle_Homo sapiens_hsa047210.83127659
40Influenza A_Homo sapiens_hsa051640.82143587
41Calcium signaling pathway_Homo sapiens_hsa040200.78347962
42cAMP signaling pathway_Homo sapiens_hsa040240.78157374
43Tyrosine metabolism_Homo sapiens_hsa003500.75796245
44Hedgehog signaling pathway_Homo sapiens_hsa043400.74522494
45Fat digestion and absorption_Homo sapiens_hsa049750.72056940
46Thyroid hormone signaling pathway_Homo sapiens_hsa049190.71874536
47PPAR signaling pathway_Homo sapiens_hsa033200.69256042
48Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.68111989
49Morphine addiction_Homo sapiens_hsa050320.67785052
50Renin-angiotensin system_Homo sapiens_hsa046140.67350507
51ABC transporters_Homo sapiens_hsa020100.67085369
52Retinol metabolism_Homo sapiens_hsa008300.65133676
53Estrogen signaling pathway_Homo sapiens_hsa049150.63947231
54Phosphatidylinositol signaling system_Homo sapiens_hsa040700.62823539
55Basal transcription factors_Homo sapiens_hsa030220.62641419
56Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.60827214
57Nicotine addiction_Homo sapiens_hsa050330.59138189
58Glycerolipid metabolism_Homo sapiens_hsa005610.56139797
59Circadian entrainment_Homo sapiens_hsa047130.55747037
60Purine metabolism_Homo sapiens_hsa002300.55302440
61Primary bile acid biosynthesis_Homo sapiens_hsa001200.54324601
62Maturity onset diabetes of the young_Homo sapiens_hsa049500.53475631
63mRNA surveillance pathway_Homo sapiens_hsa030150.53084363
64Selenocompound metabolism_Homo sapiens_hsa004500.50597787
65Fanconi anemia pathway_Homo sapiens_hsa034600.50316964
66Aldosterone synthesis and secretion_Homo sapiens_hsa049250.49408796
67MAPK signaling pathway_Homo sapiens_hsa040100.48651789
68Insulin secretion_Homo sapiens_hsa049110.46545227
69Acute myeloid leukemia_Homo sapiens_hsa052210.45408371
70Renin secretion_Homo sapiens_hsa049240.44654834
71VEGF signaling pathway_Homo sapiens_hsa043700.44585286
72Gastric acid secretion_Homo sapiens_hsa049710.43187408
73Carbohydrate digestion and absorption_Homo sapiens_hsa049730.41714944
74Vascular smooth muscle contraction_Homo sapiens_hsa042700.41132526
75Glutamatergic synapse_Homo sapiens_hsa047240.40363533
76Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.40085189
77Bile secretion_Homo sapiens_hsa049760.39795043
78Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.38769585
79Viral carcinogenesis_Homo sapiens_hsa052030.35382038
80Tight junction_Homo sapiens_hsa045300.35054301
81Cholinergic synapse_Homo sapiens_hsa047250.30753082
82Jak-STAT signaling pathway_Homo sapiens_hsa046300.26247611
83Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.25791599
84cGMP-PKG signaling pathway_Homo sapiens_hsa040220.25120487
85Herpes simplex infection_Homo sapiens_hsa051680.24371710
86Pancreatic secretion_Homo sapiens_hsa049720.23154085
87Oxytocin signaling pathway_Homo sapiens_hsa049210.23126293
88Serotonergic synapse_Homo sapiens_hsa047260.22612727
89Transcriptional misregulation in cancer_Homo sapiens_hsa052020.20218808
90ECM-receptor interaction_Homo sapiens_hsa045120.19284695
91Prolactin signaling pathway_Homo sapiens_hsa049170.17453330
92Huntingtons disease_Homo sapiens_hsa050160.15917321
93Long-term potentiation_Homo sapiens_hsa047200.15216225
94Epstein-Barr virus infection_Homo sapiens_hsa051690.14611806
95Nitrogen metabolism_Homo sapiens_hsa009100.14241776
96Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.11984391
97Vitamin B6 metabolism_Homo sapiens_hsa007500.11925248
98Legionellosis_Homo sapiens_hsa051340.11350999
99Steroid hormone biosynthesis_Homo sapiens_hsa001400.11103456
100Metabolic pathways_Homo sapiens_hsa011000.10621728

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »