OR7E28P

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1poly(A)+ mRNA export from nucleus (GO:0016973)8.17064406
2regulation of non-canonical Wnt signaling pathway (GO:2000050)7.29434022
3acrosome reaction (GO:0007340)6.66798423
4multicellular organism reproduction (GO:0032504)6.39764604
5mitochondrial calcium ion transport (GO:0006851)6.23188451
6male sex determination (GO:0030238)6.06532898
7mitochondrial DNA replication (GO:0006264)5.75765464
8cell differentiation involved in metanephros development (GO:0072202)5.73286857
9fusion of sperm to egg plasma membrane (GO:0007342)5.61210423
10peptidyl-threonine dephosphorylation (GO:0035970)5.60561127
11regulation of receptor recycling (GO:0001919)5.42604092
12negative regulation of hormone biosynthetic process (GO:0032353)5.16958747
13RNA destabilization (GO:0050779)4.98154287
14reproduction (GO:0000003)4.93828068
15mesenchymal cell differentiation involved in kidney development (GO:0072161)4.90799911
16mesenchymal cell differentiation involved in renal system development (GO:2001012)4.90799911
17sex determination (GO:0007530)4.89094554
18sperm-egg recognition (GO:0035036)4.82720133
19Leydig cell differentiation (GO:0033327)4.79740803
20positive regulation of meiosis (GO:0045836)4.79467069
21motile cilium assembly (GO:0044458)4.76101373
22hypothalamus development (GO:0021854)4.73729949
23positive regulation of smoothened signaling pathway (GO:0045880)4.63975992
24receptor recycling (GO:0001881)4.58470280
25positive regulation of meiotic cell cycle (GO:0051446)4.48020282
26negative regulation of hormone metabolic process (GO:0032351)4.41937932
27water-soluble vitamin biosynthetic process (GO:0042364)4.36485956
28relaxation of cardiac muscle (GO:0055119)4.33529831
29endosome organization (GO:0007032)4.11090440
30intraciliary transport (GO:0042073)4.10378305
31regulation of sequestering of triglyceride (GO:0010889)4.09495413
32protein localization to cilium (GO:0061512)3.99688708
33pyrimidine-containing compound transmembrane transport (GO:0072531)3.95758401
34cell-cell recognition (GO:0009988)3.92631422
35positive regulation of mitochondrial calcium ion concentration (GO:0051561)3.92358774
36sperm motility (GO:0030317)3.85462103
37calcium ion-dependent exocytosis (GO:0017156)3.81562443
38negative regulation of NF-kappaB import into nucleus (GO:0042347)3.80293234
39negative regulation of transcription regulatory region DNA binding (GO:2000678)3.75596211
40DNA damage response, detection of DNA damage (GO:0042769)3.73010664
41mitochondrial DNA metabolic process (GO:0032042)3.71182280
42bone morphogenesis (GO:0060349)3.67378593
43limb development (GO:0060173)3.67066542
44appendage development (GO:0048736)3.67066542
45single fertilization (GO:0007338)3.58458754
46oocyte development (GO:0048599)3.54967689
47hematopoietic stem cell proliferation (GO:0071425)3.54748696
48cellular ketone body metabolic process (GO:0046950)3.50665311
49regulation of male gonad development (GO:2000018)3.46858410
50regulation of meiosis I (GO:0060631)3.46022225
51cytoplasmic mRNA processing body assembly (GO:0033962)3.41329760
52termination of G-protein coupled receptor signaling pathway (GO:0038032)3.34740943
53regulation of triglyceride biosynthetic process (GO:0010866)3.34537105
54membrane repolarization during cardiac muscle cell action potential (GO:0086013)3.34410281
55adrenal gland development (GO:0030325)3.34176761
56spermatid nucleus differentiation (GO:0007289)3.32284473
57chromosome condensation (GO:0030261)3.27724562
58ketone body metabolic process (GO:1902224)3.25531611
59somite development (GO:0061053)3.22910756
60binding of sperm to zona pellucida (GO:0007339)3.21918693
61locomotory exploration behavior (GO:0035641)3.21910334
62pituitary gland development (GO:0021983)3.20196252
63regulation of glucocorticoid metabolic process (GO:0031943)3.16746697
64microtubule depolymerization (GO:0007019)3.15812369
65single strand break repair (GO:0000012)3.13527099
66lipid particle organization (GO:0034389)3.11738195
67membrane repolarization during action potential (GO:0086011)3.04830455
68relaxation of muscle (GO:0090075)3.03958395
69termination of signal transduction (GO:0023021)3.01484049
70negative regulation of Rho protein signal transduction (GO:0035024)2.97324454
71establishment of protein localization to Golgi (GO:0072600)2.92659835
72sperm capacitation (GO:0048240)2.90626984
73protein targeting to Golgi (GO:0000042)2.90428033
74nucleosome disassembly (GO:0006337)2.82705242
75protein-DNA complex disassembly (GO:0032986)2.82705242
76positive regulation of growth hormone secretion (GO:0060124)2.81522114
77DNA packaging (GO:0006323)2.77577596
78neurofilament cytoskeleton organization (GO:0060052)2.75845521
79negative regulation of cAMP-mediated signaling (GO:0043951)2.75214943
80response to acidic pH (GO:0010447)2.72668719
81smoothened signaling pathway (GO:0007224)2.72273076
82regulation of interleukin-6 biosynthetic process (GO:0045408)2.72229328
83protein localization to Golgi apparatus (GO:0034067)2.69928445
84coenzyme catabolic process (GO:0009109)2.67775101
85negative regulation of gluconeogenesis (GO:0045721)2.67618377
86chondrocyte differentiation (GO:0002062)2.61222085
87retrograde transport, vesicle recycling within Golgi (GO:0000301)2.60004204
88protein polyglutamylation (GO:0018095)2.59351258
89cilium assembly (GO:0042384)2.58881719
90melanosome transport (GO:0032402)2.58438184
91cellular response to pH (GO:0071467)2.57509632
92lipopolysaccharide biosynthetic process (GO:0009103)2.55833259
93cilium organization (GO:0044782)2.53025153
94embryonic body morphogenesis (GO:0010172)2.50845587
95regulation of smoothened signaling pathway (GO:0008589)2.50288611
96positive regulation of gastrulation (GO:2000543)2.50225084
97pigment granule transport (GO:0051904)2.49068087
98response to pheromone (GO:0019236)17.0348837
99plasma membrane fusion (GO:0045026)13.0541015
100positive regulation of receptor recycling (GO:0001921)10.5957551

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1STAT6_21828071_ChIP-Seq_BEAS2B_Human2.84070441
2TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.63687550
3POU5F1_26923725_Chip-Seq_MESODERM_Mouse2.63687550
4HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse2.53299411
5FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.45560346
6CDX2_19796622_ChIP-Seq_MESCs_Mouse2.24356554
7EED_16625203_ChIP-ChIP_MESCs_Mouse2.06858044
8GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.99067958
9CTBP1_25329375_ChIP-Seq_LNCAP_Human1.97953762
10RNF2_27304074_Chip-Seq_NSC_Mouse1.95073454
11PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.88365041
12BMI1_23680149_ChIP-Seq_NPCS_Mouse1.85522779
13TOP2B_26459242_ChIP-Seq_MCF-7_Human1.84390482
14IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.84260808
15CBP_20019798_ChIP-Seq_JUKART_Human1.84260808
16PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.82637120
17EZH2_27304074_Chip-Seq_ESCs_Mouse1.81986510
18ER_23166858_ChIP-Seq_MCF-7_Human1.78982782
19CTBP2_25329375_ChIP-Seq_LNCAP_Human1.77559626
20SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.77402354
21REST_21632747_ChIP-Seq_MESCs_Mouse1.76265691
22EZH2_22144423_ChIP-Seq_EOC_Human1.74467178
23IRF1_19129219_ChIP-ChIP_H3396_Human1.73656408
24SUZ12_27294783_Chip-Seq_ESCs_Mouse1.72877893
25UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.71974383
26SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.69990294
27NR3C1_23031785_ChIP-Seq_PC12_Mouse1.69349360
28THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.68417463
29SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.65768597
30STAT1_20625510_ChIP-Seq_HELA_Human1.61150534
31TP53_18474530_ChIP-ChIP_U2OS_Human1.60578634
32E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.59396724
33EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.57484798
34AR_25329375_ChIP-Seq_VCAP_Human1.56593910
35SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.52128367
36ETV1_20927104_ChIP-Seq_GIST48_Human1.51128766
37ZFP57_27257070_Chip-Seq_ESCs_Mouse1.49266549
38SMAD3_21741376_ChIP-Seq_EPCs_Human1.47480844
39RNF2_18974828_ChIP-Seq_MESCs_Mouse1.46796813
40EZH2_18974828_ChIP-Seq_MESCs_Mouse1.46796813
41P300_19829295_ChIP-Seq_ESCs_Human1.46750290
42JARID2_20064375_ChIP-Seq_MESCs_Mouse1.45903181
43SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.45795173
44MYC_19829295_ChIP-Seq_ESCs_Human1.43964506
45CBX2_27304074_Chip-Seq_ESCs_Mouse1.41653143
46EZH2_27294783_Chip-Seq_ESCs_Mouse1.39917785
47TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.39688380
48CBX2_22325352_ChIP-Seq_293T-Rex_Human1.39542005
49AHR_22903824_ChIP-Seq_MCF-7_Human1.38417698
50TP63_19390658_ChIP-ChIP_HaCaT_Human1.38073699
51REST_18959480_ChIP-ChIP_MESCs_Mouse1.36955298
52MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.36458944
53TAF15_26573619_Chip-Seq_HEK293_Human1.35216603
54MTF2_20144788_ChIP-Seq_MESCs_Mouse1.35188221
55ARNT_22903824_ChIP-Seq_MCF-7_Human1.35014294
56RBPJ_21746931_ChIP-Seq_IB4_Human1.34551795
57AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.30979685
58P53_22127205_ChIP-Seq_FIBROBLAST_Human1.29607252
59PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.29118144
60RARB_27405468_Chip-Seq_BRAIN_Mouse1.28224523
61POU3F2_20337985_ChIP-ChIP_501MEL_Human1.27524649
62SMAD4_21741376_ChIP-Seq_EPCs_Human1.26759262
63FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.26515419
64FUS_26573619_Chip-Seq_HEK293_Human1.25396479
65EWS_26573619_Chip-Seq_HEK293_Human1.24985965
66LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.24816417
67HOXB7_26014856_ChIP-Seq_BT474_Human1.23436309
68NANOG_18555785_Chip-Seq_ESCs_Mouse1.21937476
69SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.20709924
70BCAT_22108803_ChIP-Seq_LS180_Human1.20535664
71TCF4_22108803_ChIP-Seq_LS180_Human1.19923299
72NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.19123003
73CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.16291600
74SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.16238301
75AUTS2_25519132_ChIP-Seq_293T-REX_Human1.14253665
76JARID2_20075857_ChIP-Seq_MESCs_Mouse1.13678914
77OCT1_27270436_Chip-Seq_PROSTATE_Human1.13105848
78TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.13018909
79HNFA_21074721_ChIP-Seq_CACO-2_Human1.12677643
80RUNX2_22187159_ChIP-Seq_PCA_Human1.12235141
81NANOG_19829295_ChIP-Seq_ESCs_Human1.11333371
82SOX2_19829295_ChIP-Seq_ESCs_Human1.11333371
83RNF2_27304074_Chip-Seq_ESCs_Mouse1.11001259
84FOXH1_21741376_ChIP-Seq_ESCs_Human1.09375047
85SMAD4_21741376_ChIP-Seq_HESCs_Human1.09123083
86E2F1_20622854_ChIP-Seq_HELA_Human1.09059451
87TBL1_22424771_ChIP-Seq_293T_Human1.08850280
88NFYB_21822215_ChIP-Seq_K562_Human1.08551495
89SMAD4_21799915_ChIP-Seq_A2780_Human1.07943454
90TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.07848300
91GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.07599195
92PKCTHETA_26484144_Chip-Seq_BREAST_Human1.06758755
93FOXH1_21741376_ChIP-Seq_EPCs_Human1.06666444
94STAT3_23295773_ChIP-Seq_U87_Human1.06617877
95TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.06306248
96RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.04577746
97EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.02450980
98SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.02134251
99MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.01549652
100DROSHA_22980978_ChIP-Seq_HELA_Human1.01474916

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization6.38304576
2MP0003122_maternal_imprinting4.72541639
3MP0001348_abnormal_lacrimal_gland3.72546905
4MP0003011_delayed_dark_adaptation3.64192568
5MP0009046_muscle_twitch3.52906839
6MP0002909_abnormal_adrenal_gland3.46642992
7MP0001188_hyperpigmentation2.98298388
8MP0003121_genomic_imprinting2.92715412
9MP0002822_catalepsy2.79809871
10MP0005379_endocrine/exocrine_gland_phen2.76513095
11MP0003283_abnormal_digestive_organ2.54816132
12MP0009053_abnormal_anal_canal2.43799242
13MP0003698_abnormal_male_reproductive2.25122126
14MP0006072_abnormal_retinal_apoptosis1.98566875
15MP0002735_abnormal_chemical_nociception1.94101730
16MP0002272_abnormal_nervous_system1.82501350
17MP0001919_abnormal_reproductive_system1.68924580
18MP0001929_abnormal_gametogenesis1.65357211
19MP0002184_abnormal_innervation1.61889927
20MP0000631_abnormal_neuroendocrine_gland1.57743986
21MP0003878_abnormal_ear_physiology1.57722470
22MP0005377_hearing/vestibular/ear_phenot1.57722470
23MP0005253_abnormal_eye_physiology1.56681400
24MP0000955_abnormal_spinal_cord1.53420576
25MP0003195_calcinosis1.53385660
26MP0001440_abnormal_grooming_behavior1.49438876
27MP0005670_abnormal_white_adipose1.46439923
28MP0000566_synostosis1.45980439
29MP0000639_abnormal_adrenal_gland1.45826739
30MP0001542_abnormal_bone_strength1.45403222
31MP0006292_abnormal_olfactory_placode1.44534991
32MP0002138_abnormal_hepatobiliary_system1.40377722
33MP0005423_abnormal_somatic_nervous1.39268626
34MP0004134_abnormal_chest_morphology1.35326777
35MP0005084_abnormal_gallbladder_morpholo1.27256079
36MP0001486_abnormal_startle_reflex1.23799902
37MP0004885_abnormal_endolymph1.22651999
38MP0009697_abnormal_copulation1.21314587
39MP0000470_abnormal_stomach_morphology1.21270488
40MP0008961_abnormal_basal_metabolism1.19627240
41MP0000230_abnormal_systemic_arterial1.16642609
42MP0001984_abnormal_olfaction1.14682323
43MP0004147_increased_porphyrin_level1.14615167
44MP0002210_abnormal_sex_determination1.13030220
45MP0002876_abnormal_thyroid_physiology1.12110718
46MP0005389_reproductive_system_phenotype1.11912405
47MP0002557_abnormal_social/conspecific_i1.11413576
48MP0003635_abnormal_synaptic_transmissio1.11374918
49MP0002229_neurodegeneration1.09709573
50MP0001986_abnormal_taste_sensitivity1.07600062
51MP0008569_lethality_at_weaning1.06828193
52MP0005248_abnormal_Harderian_gland1.06803390
53MP0002161_abnormal_fertility/fecundity1.05967814
54MP0000534_abnormal_ureter_morphology1.04550632
55MP0003787_abnormal_imprinting1.03516597
56MP0002734_abnormal_mechanical_nocicepti1.02799727
57MP0005551_abnormal_eye_electrophysiolog1.01594767
58MP0000778_abnormal_nervous_system0.98947816
59MP0002882_abnormal_neuron_morphology0.97732516
60MP0006276_abnormal_autonomic_nervous0.97134646
61MP0001970_abnormal_pain_threshold0.96759430
62MP0004811_abnormal_neuron_physiology0.96532700
63MP0000049_abnormal_middle_ear0.94413861
64MP0004142_abnormal_muscle_tone0.91528312
65MP0003119_abnormal_digestive_system0.91157701
66MP0001145_abnormal_male_reproductive0.90973467
67MP0000653_abnormal_sex_gland0.90674722
68MP0002928_abnormal_bile_duct0.90324811
69MP0002063_abnormal_learning/memory/cond0.89524513
70MP0003936_abnormal_reproductive_system0.88902787
71MP0002932_abnormal_joint_morphology0.88828828
72MP0002102_abnormal_ear_morphology0.88452368
73MP0008789_abnormal_olfactory_epithelium0.88362461
74MP0002160_abnormal_reproductive_system0.86441330
75MP0009745_abnormal_behavioral_response0.84154980
76MP0005646_abnormal_pituitary_gland0.81870123
77MP0002166_altered_tumor_susceptibility0.81842699
78MP0005220_abnormal_exocrine_pancreas0.81418813
79MP0003942_abnormal_urinary_system0.80392472
80MP0002572_abnormal_emotion/affect_behav0.79969818
81MP0005391_vision/eye_phenotype0.79362006
82MP0001664_abnormal_digestion0.78830089
83MP0005595_abnormal_vascular_smooth0.74284395
84MP0009379_abnormal_foot_pigmentation0.74185675
85MP0004859_abnormal_synaptic_plasticity0.73997488
86MP0003880_abnormal_central_pattern0.72228335
87MP0005499_abnormal_olfactory_system0.72030293
88MP0005394_taste/olfaction_phenotype0.72030293
89MP0000750_abnormal_muscle_regeneration0.71684932
90MP0003656_abnormal_erythrocyte_physiolo0.70927623
91MP0005448_abnormal_energy_balance0.69339673
92MP0000516_abnormal_urinary_system0.69245146
93MP0005367_renal/urinary_system_phenotyp0.69245146
94MP0001756_abnormal_urination0.67855748
95MP0002332_abnormal_exercise_endurance0.66375701
96MP0001944_abnormal_pancreas_morphology0.65447896
97MP0004085_abnormal_heartbeat0.64613982
98MP0005083_abnormal_biliary_tract0.64250283
99MP0002064_seizures0.63851757
100MP0000427_abnormal_hair_cycle0.62824986

Predicted human phenotypes

RankGene SetZ-score
1Sex reversal (HP:0012245)9.33205446
2Abnormal sex determination (HP:0012244)9.33205446
3Mesomelia (HP:0003027)9.25918403
4Median cleft lip (HP:0000161)6.14429255
5Arthropathy (HP:0003040)5.70298306
6Wrist flexion contracture (HP:0001239)5.39494749
7Facial cleft (HP:0002006)5.39081913
8Broad palm (HP:0001169)5.21899189
9Unilateral renal agenesis (HP:0000122)4.35776116
10Adrenal hypoplasia (HP:0000835)4.22139891
11Gonadal dysgenesis (HP:0000133)3.98644669
12Difficulty running (HP:0009046)3.90289967
13Rhizomelia (HP:0008905)3.77598111
14Testicular neoplasm (HP:0010788)3.73847018
15Renal salt wasting (HP:0000127)3.70773787
16Gout (HP:0001997)3.59297144
17Abnormality of the fingertips (HP:0001211)3.58039500
18Abnormality of macular pigmentation (HP:0008002)3.56348053
19Large for gestational age (HP:0001520)3.36584651
20Aplasia/hypoplasia of the uterus (HP:0008684)3.21925155
21Severe visual impairment (HP:0001141)3.04759783
22Hyponatremia (HP:0002902)3.01256838
23Postaxial foot polydactyly (HP:0001830)2.96240135
24Hypogonadotrophic hypogonadism (HP:0000044)2.94422857
25Congenital hepatic fibrosis (HP:0002612)2.89596164
26Sensory axonal neuropathy (HP:0003390)2.84151349
27Autoimmune hemolytic anemia (HP:0001890)2.73978455
28Hypoplastic ischia (HP:0003175)2.70969356
29Abnormality of sodium homeostasis (HP:0010931)2.65881650
30Large eyes (HP:0001090)2.64324207
31Spinal muscular atrophy (HP:0007269)2.58683807
32Short thorax (HP:0010306)2.51522587
33Male pseudohermaphroditism (HP:0000037)2.48877816
34Exercise-induced muscle cramps (HP:0003710)2.44821071
35Bony spicule pigmentary retinopathy (HP:0007737)2.28940074
36Short foot (HP:0001773)2.27887955
37Abnormality of the ischium (HP:0003174)2.24586999
38Torticollis (HP:0000473)2.23730521
39Ectopic anus (HP:0004397)2.23428041
40Preaxial hand polydactyly (HP:0001177)2.20846099
41Azoospermia (HP:0000027)2.19269633
42Omphalocele (HP:0001539)2.16571269
43Delayed puberty (HP:0000823)2.11511269
44Narrow chest (HP:0000774)2.08440801
45Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.07727117
46Postaxial hand polydactyly (HP:0001162)2.07154062
47Increased purine levels (HP:0004368)2.02819188
48Hyperuricemia (HP:0002149)2.02819188
49Polyphagia (HP:0002591)2.02394725
50Hyporeflexia of lower limbs (HP:0002600)2.00674931
51Myotonia (HP:0002486)1.98253894
52Abnormal drinking behavior (HP:0030082)1.97885597
53Polydipsia (HP:0001959)1.97885597
54Hypergammaglobulinemia (HP:0010702)1.97680029
55Neoplasm of striated muscle (HP:0009728)1.96053110
56Tubulointerstitial nephritis (HP:0001970)1.95083356
57Volvulus (HP:0002580)1.95073041
58Coxa vara (HP:0002812)1.93189907
59Rhabdomyosarcoma (HP:0002859)1.92500505
60Medial flaring of the eyebrow (HP:0010747)1.92065986
61Reticulocytopenia (HP:0001896)1.89968780
62Congenital primary aphakia (HP:0007707)1.88881893
63Hyperinsulinemic hypoglycemia (HP:0000825)1.88844285
64Nephronophthisis (HP:0000090)1.87973515
65Abnormality of the renal medulla (HP:0100957)1.86663565
66Gait imbalance (HP:0002141)1.81967196
67Type I transferrin isoform profile (HP:0003642)1.81466928
68Mesangial abnormality (HP:0001966)1.78852175
69Slow-growing hair (HP:0002217)1.77614778
70Abnormality of hair growth rate (HP:0011363)1.77614778
71Attenuation of retinal blood vessels (HP:0007843)1.76541026
72Abnormal rod and cone electroretinograms (HP:0008323)1.76472963
73Neoplasm of the oral cavity (HP:0100649)1.76231274
74Vaginal atresia (HP:0000148)1.74756655
75Nephropathy (HP:0000112)1.74715259
76Long eyelashes (HP:0000527)1.74455389
77Patchy hypopigmentation of hair (HP:0011365)1.73609036
78Neonatal short-limb short stature (HP:0008921)1.73305283
79Anxiety (HP:0000739)1.70860383
80Genital tract atresia (HP:0001827)1.70487902
81Frequent falls (HP:0002359)1.70445200
82Pendular nystagmus (HP:0012043)1.68678756
83Small hand (HP:0200055)1.68414209
84Rib fusion (HP:0000902)1.67896126
85Nephrogenic diabetes insipidus (HP:0009806)1.64261305
86Papillary thyroid carcinoma (HP:0002895)1.63563824
87Tubular atrophy (HP:0000092)1.63002347
88Polycystic kidney dysplasia (HP:0000113)1.61910740
89Aplasia/Hypoplasia of the hallux (HP:0008362)1.60698164
90Shawl scrotum (HP:0000049)1.60101031
91Facial shape deformation (HP:0011334)1.59991438
92Potter facies (HP:0002009)1.59991438
93Muscular dystrophy (HP:0003560)1.59934747
94Poor coordination (HP:0002370)1.59327302
95Congenital, generalized hypertrichosis (HP:0004540)1.59253554
96Flattened epiphyses (HP:0003071)1.57576440
97Abnormality of the renal cortex (HP:0011035)1.57529182
983-Methylglutaconic aciduria (HP:0003535)1.54767320
99Bulbous nose (HP:0000414)1.54154638
100Abnormal eating behavior (HP:0100738)1.53456221

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FER8.01335236
2AKT32.69590509
3CAMK12.56211820
4FES10.3220150
5PRKCE1.87549880
6MST41.86423595
7FRK1.83745361
8PLK21.82901238
9UHMK11.81428792
10DDR21.79397792
11INSRR1.71475048
12WNK11.58275407
13PNCK1.57400418
14MAP4K21.52293683
15PLK41.45821882
16STK38L1.39211755
17MINK11.37821869
18MST1R1.22319673
19CAMK1G1.18081615
20NTRK31.09753128
21NUAK11.09127008
22BMPR21.00269107
23GRK10.87515249
24CDK190.87062846
25PINK10.86782277
26ADRBK20.86753863
27BMPR1B0.85475642
28BRAF0.85308211
29HIPK20.85299665
30OXSR10.82764957
31MAP3K90.78271577
32ILK0.77374744
33ZAP700.75343172
34DYRK20.74864097
35TGFBR10.74255341
36MAPK150.73875659
37CSNK1A10.73478797
38TESK10.71376622
39SGK20.70894749
40MARK10.70700134
41STK240.69384406
42FGFR20.63785258
43STK380.63016713
44PRKCG0.61933132
45MET0.61599583
46STK110.60191737
47CASK0.59484137
48CAMK1D0.54110784
49SGK2230.53598891
50SGK4940.53598891
51KIT0.52712293
52EPHA40.50803473
53TLK10.50448685
54GRK60.50366210
55PRKG10.50217355
56TRIM280.50121295
57PTK2B0.48728043
58JAK20.48484993
59STK390.46857452
60MYLK0.46685716
61PAK10.44711940
62WNK40.43498963
63PKN10.43489847
64CHUK0.42561194
65PASK0.41607850
66TAOK10.41460642
67CSNK1E0.40473638
68PRKACA0.38327163
69ERBB30.38289114
70CDK50.37747574
71PRKD30.36602127
72ACVR1B0.35015113
73PRKAA20.33408088
74BRSK20.32224211
75NME10.31141181
76CDK40.30341985
77PRKCA0.27873317
78MTOR0.27742358
79ADRBK10.27352649
80DAPK20.26300400
81TAOK30.26110693
82PRKACG0.26110634
83PRKCQ0.26054738
84NTRK20.25712413
85PRKACB0.24990092
86ALK0.24727885
87MAPKAPK50.24415257
88GRK50.22499420
89CSNK1G20.21860917
90ABL20.21396669
91CSNK1G10.21097307
92AKT10.20361178
93IRAK10.20321989
94PDK10.19742432
95PRKCD0.19521295
96RPS6KA30.19285713
97IKBKB0.18080924
98GSK3B0.18021029
99SGK30.17979790
100FGFR30.17870650

Predicted pathways (KEGG)

RankGene SetZ-score
1Vasopressin-regulated water reabsorption_Homo sapiens_hsa049625.78555076
2Maturity onset diabetes of the young_Homo sapiens_hsa049504.35638836
3Synthesis and degradation of ketone bodies_Homo sapiens_hsa000724.19497324
4Hedgehog signaling pathway_Homo sapiens_hsa043403.53495059
5Synaptic vesicle cycle_Homo sapiens_hsa047213.23311843
6Insulin secretion_Homo sapiens_hsa049112.78470657
7GABAergic synapse_Homo sapiens_hsa047272.29328797
8Olfactory transduction_Homo sapiens_hsa047401.77512610
9Parkinsons disease_Homo sapiens_hsa050121.64112850
10Gastric acid secretion_Homo sapiens_hsa049711.60025465
11Butanoate metabolism_Homo sapiens_hsa006501.56282130
12Lysine degradation_Homo sapiens_hsa003101.56063345
13Dorso-ventral axis formation_Homo sapiens_hsa043201.54665340
14AMPK signaling pathway_Homo sapiens_hsa041521.49380889
15Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.48569524
16Oxidative phosphorylation_Homo sapiens_hsa001901.48031207
17Vascular smooth muscle contraction_Homo sapiens_hsa042701.47340121
18Adipocytokine signaling pathway_Homo sapiens_hsa049201.45263855
19Long-term depression_Homo sapiens_hsa047301.40582380
20Oxytocin signaling pathway_Homo sapiens_hsa049211.38703403
21N-Glycan biosynthesis_Homo sapiens_hsa005101.37634331
22cGMP-PKG signaling pathway_Homo sapiens_hsa040221.25955041
23Phototransduction_Homo sapiens_hsa047441.25351087
24Ribosome_Homo sapiens_hsa030101.25102671
25Renin secretion_Homo sapiens_hsa049241.20642386
26Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.14652559
27Glycerolipid metabolism_Homo sapiens_hsa005611.13124713
28Type II diabetes mellitus_Homo sapiens_hsa049301.11807045
29Longevity regulating pathway - mammal_Homo sapiens_hsa042111.09936872
30Circadian rhythm_Homo sapiens_hsa047101.08040251
31Alcoholism_Homo sapiens_hsa050341.07753190
32Collecting duct acid secretion_Homo sapiens_hsa049661.07081597
33Retinol metabolism_Homo sapiens_hsa008300.94706309
34Huntingtons disease_Homo sapiens_hsa050160.94702842
35Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.94378086
36Cardiac muscle contraction_Homo sapiens_hsa042600.93542373
37Circadian entrainment_Homo sapiens_hsa047130.90485844
38Pentose and glucuronate interconversions_Homo sapiens_hsa000400.89863466
39Regulation of autophagy_Homo sapiens_hsa041400.88995731
40Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.87071711
41Cocaine addiction_Homo sapiens_hsa050300.85912202
42Phenylalanine metabolism_Homo sapiens_hsa003600.84684499
43Thyroid hormone synthesis_Homo sapiens_hsa049180.84493602
44Thyroid hormone signaling pathway_Homo sapiens_hsa049190.82111077
45Jak-STAT signaling pathway_Homo sapiens_hsa046300.81656206
46RNA transport_Homo sapiens_hsa030130.79934441
47Glutamatergic synapse_Homo sapiens_hsa047240.79811038
48Endocytosis_Homo sapiens_hsa041440.79128542
49Chemical carcinogenesis_Homo sapiens_hsa052040.77859203
50Cholinergic synapse_Homo sapiens_hsa047250.77294838
51Taste transduction_Homo sapiens_hsa047420.76583476
52Wnt signaling pathway_Homo sapiens_hsa043100.76557995
53Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.75426000
54Serotonergic synapse_Homo sapiens_hsa047260.73533717
55Histidine metabolism_Homo sapiens_hsa003400.73314667
56Galactose metabolism_Homo sapiens_hsa000520.73118907
57Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.72587400
58Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.71292333
59Tyrosine metabolism_Homo sapiens_hsa003500.69231391
60Tryptophan metabolism_Homo sapiens_hsa003800.66022998
61MAPK signaling pathway_Homo sapiens_hsa040100.65484149
62Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.63570721
63Dopaminergic synapse_Homo sapiens_hsa047280.63303663
64Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.61136552
65Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.58835421
66Morphine addiction_Homo sapiens_hsa050320.58712761
67Vitamin digestion and absorption_Homo sapiens_hsa049770.57625714
68Steroid hormone biosynthesis_Homo sapiens_hsa001400.57505568
69Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.57454600
70Protein digestion and absorption_Homo sapiens_hsa049740.57361408
71mRNA surveillance pathway_Homo sapiens_hsa030150.57037092
72Salivary secretion_Homo sapiens_hsa049700.53451142
73RNA degradation_Homo sapiens_hsa030180.52485615
74Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.51119626
75Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.51114553
76Axon guidance_Homo sapiens_hsa043600.49775426
77Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.49589155
78Basal cell carcinoma_Homo sapiens_hsa052170.48965172
79Carbohydrate digestion and absorption_Homo sapiens_hsa049730.48937026
80Melanogenesis_Homo sapiens_hsa049160.48526491
81Aldosterone synthesis and secretion_Homo sapiens_hsa049250.46895240
82Type I diabetes mellitus_Homo sapiens_hsa049400.46056950
83Linoleic acid metabolism_Homo sapiens_hsa005910.44746250
84Alzheimers disease_Homo sapiens_hsa050100.43503533
85cAMP signaling pathway_Homo sapiens_hsa040240.43268816
86Fructose and mannose metabolism_Homo sapiens_hsa000510.42979785
87Fatty acid biosynthesis_Homo sapiens_hsa000610.42222117
88Ovarian steroidogenesis_Homo sapiens_hsa049130.40331554
89Notch signaling pathway_Homo sapiens_hsa043300.39596005
90Ether lipid metabolism_Homo sapiens_hsa005650.39448276
91Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.38970027
92Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.38806434
93Mineral absorption_Homo sapiens_hsa049780.38553931
94Estrogen signaling pathway_Homo sapiens_hsa049150.38491377
95Gap junction_Homo sapiens_hsa045400.37976115
96Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.37735895
97Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.36329824
98Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.32759421
99Calcium signaling pathway_Homo sapiens_hsa040200.30177063
100Amphetamine addiction_Homo sapiens_hsa050310.26835123

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