

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | female gonad development (GO:0008585) | 9.19215792 |
| 2 | regulation of telomere maintenance via telomerase (GO:0032210) | 8.20713356 |
| 3 | inner mitochondrial membrane organization (GO:0007007) | 7.38965885 |
| 4 | cranial suture morphogenesis (GO:0060363) | 7.21849681 |
| 5 | male meiosis (GO:0007140) | 7.18746199 |
| 6 | stress granule assembly (GO:0034063) | 6.75648986 |
| 7 | central nervous system neuron axonogenesis (GO:0021955) | 6.75446807 |
| 8 | negative regulation of telomere maintenance (GO:0032205) | 6.57634066 |
| 9 | cellular response to hepatocyte growth factor stimulus (GO:0035729) | 6.34657856 |
| 10 | response to hepatocyte growth factor (GO:0035728) | 6.34657856 |
| 11 | thyroid hormone generation (GO:0006590) | 6.32308745 |
| 12 | negative regulation of epidermal growth factor-activated receptor activity (GO:0007175) | 6.28052743 |
| 13 | peptidyl-lysine dimethylation (GO:0018027) | 6.11828937 |
| 14 | negative regulation of glycoprotein biosynthetic process (GO:0010561) | 6.11433726 |
| 15 | regulation of protein glycosylation (GO:0060049) | 6.02976618 |
| 16 | positive regulation of keratinocyte differentiation (GO:0045618) | 6.00407565 |
| 17 | regulation of G0 to G1 transition (GO:0070316) | 5.98672625 |
| 18 | ventricular trabecula myocardium morphogenesis (GO:0003222) | 5.89379986 |
| 19 | DNA strand renaturation (GO:0000733) | 5.67489510 |
| 20 | apoptotic DNA fragmentation (GO:0006309) | 5.62856611 |
| 21 | lipid translocation (GO:0034204) | 5.59754175 |
| 22 | phospholipid translocation (GO:0045332) | 5.59754175 |
| 23 | centrosome duplication (GO:0051298) | 5.57585671 |
| 24 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 5.49236658 |
| 25 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 5.49236658 |
| 26 | thyroid hormone metabolic process (GO:0042403) | 5.15280412 |
| 27 | regulation of natural killer cell mediated immunity (GO:0002715) | 5.09382859 |
| 28 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 5.09382859 |
| 29 | intermediate filament cytoskeleton organization (GO:0045104) | 4.92674688 |
| 30 | negative regulation of keratinocyte proliferation (GO:0010839) | 4.92046168 |
| 31 | intermediate filament-based process (GO:0045103) | 4.79819996 |
| 32 | heart trabecula morphogenesis (GO:0061384) | 4.75165474 |
| 33 | mitotic G2 DNA damage checkpoint (GO:0007095) | 4.74592246 |
| 34 | negative regulation of glycoprotein metabolic process (GO:1903019) | 4.66540673 |
| 35 | regulation of sister chromatid cohesion (GO:0007063) | 4.64579711 |
| 36 | craniofacial suture morphogenesis (GO:0097094) | 4.54427363 |
| 37 | vitamin transmembrane transport (GO:0035461) | 4.46019249 |
| 38 | negative regulation of fatty acid biosynthetic process (GO:0045717) | 4.45184080 |
| 39 | maintenance of protein location in nucleus (GO:0051457) | 4.36936955 |
| 40 | cellular response to thyroid hormone stimulus (GO:0097067) | 4.36229097 |
| 41 | positive regulation of protein import into nucleus, translocation (GO:0033160) | 4.35706624 |
| 42 | galactose metabolic process (GO:0006012) | 4.28769248 |
| 43 | positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145) | 4.23629990 |
| 44 | trabecula morphogenesis (GO:0061383) | 4.21680328 |
| 45 | embryonic heart tube development (GO:0035050) | 4.17778195 |
| 46 | negative regulation of protein tyrosine kinase activity (GO:0061099) | 4.16276042 |
| 47 | viral protein processing (GO:0019082) | 4.14426665 |
| 48 | positive regulation of epidermal cell differentiation (GO:0045606) | 4.07332316 |
| 49 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0031146) | 4.04920182 |
| 50 | regulation of histone phosphorylation (GO:0033127) | 3.99305072 |
| 51 | negative regulation of receptor activity (GO:2000272) | 3.97938532 |
| 52 | mitotic G2/M transition checkpoint (GO:0044818) | 3.91555172 |
| 53 | protein-cofactor linkage (GO:0018065) | 3.88323728 |
| 54 | hydrogen peroxide biosynthetic process (GO:0050665) | 3.78340208 |
| 55 | androgen biosynthetic process (GO:0006702) | 3.73893995 |
| 56 | pyrimidine-containing compound transmembrane transport (GO:0072531) | 3.71378836 |
| 57 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 3.69191838 |
| 58 | regulation of translation, ncRNA-mediated (GO:0045974) | 3.69191838 |
| 59 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 3.69191838 |
| 60 | outer ear morphogenesis (GO:0042473) | 3.67369966 |
| 61 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.65704815 |
| 62 | intracellular protein transmembrane import (GO:0044743) | 3.63629753 |
| 63 | natural killer cell activation (GO:0030101) | 3.58086736 |
| 64 | mast cell activation (GO:0045576) | 3.52043001 |
| 65 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.51503701 |
| 66 | regulation of telomere maintenance (GO:0032204) | 3.48341840 |
| 67 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.47092941 |
| 68 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 3.46253150 |
| 69 | reactive oxygen species biosynthetic process (GO:1903409) | 3.44555646 |
| 70 | middle ear morphogenesis (GO:0042474) | 3.41495022 |
| 71 | RNA destabilization (GO:0050779) | 3.41469330 |
| 72 | positive regulation of transcription regulatory region DNA binding (GO:2000679) | 3.41096863 |
| 73 | mRNA transcription from RNA polymerase II promoter (GO:0042789) | 3.40557522 |
| 74 | regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043516) | 3.28546636 |
| 75 | regulation of membrane lipid distribution (GO:0097035) | 3.28106990 |
| 76 | replication fork processing (GO:0031297) | 3.27334779 |
| 77 | cell migration involved in heart development (GO:0060973) | 3.25010645 |
| 78 | vitamin transport (GO:0051180) | 3.24112278 |
| 79 | megakaryocyte development (GO:0035855) | 3.19374233 |
| 80 | peptidyl-lysine methylation (GO:0018022) | 3.17422051 |
| 81 | mammary gland epithelial cell proliferation (GO:0033598) | 3.16843064 |
| 82 | endocardial cushion morphogenesis (GO:0003203) | 3.16333410 |
| 83 | regulation of keratinocyte proliferation (GO:0010837) | 3.14720243 |
| 84 | regulation of transcription from RNA polymerase I promoter (GO:0006356) | 3.13399082 |
| 85 | response to thyroid hormone (GO:0097066) | 2.94119611 |
| 86 | regulation of voltage-gated calcium channel activity (GO:1901385) | 2.87082885 |
| 87 | acrosome assembly (GO:0001675) | 2.86749350 |
| 88 | positive regulation of cytokine-mediated signaling pathway (GO:0001961) | 2.82466825 |
| 89 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 2.81266131 |
| 90 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 2.79658862 |
| 91 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 2.76535934 |
| 92 | embryonic hindlimb morphogenesis (GO:0035116) | 2.75721849 |
| 93 | superoxide anion generation (GO:0042554) | 2.75161331 |
| 94 | regulation of keratinocyte differentiation (GO:0045616) | 2.73103746 |
| 95 | neurofilament cytoskeleton organization (GO:0060052) | 18.2345407 |
| 96 | regulation of DNA methylation (GO:0044030) | 14.7965204 |
| 97 | ectoderm development (GO:0007398) | 11.7002238 |
| 98 | glyoxylate metabolic process (GO:0046487) | 11.4155188 |
| 99 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 11.1130005 |
| 100 | chaperone-mediated protein transport (GO:0072321) | 11.0269388 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 6.11139855 |
| 2 | IGF1R_20145208_ChIP-Seq_DFB_Human | 5.35463613 |
| 3 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 4.95305698 |
| 4 | IRF1_19129219_ChIP-ChIP_H3396_Human | 4.69766707 |
| 5 | VDR_22108803_ChIP-Seq_LS180_Human | 4.42575815 |
| 6 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 4.10301027 |
| 7 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 3.83143143 |
| 8 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 3.30473833 |
| 9 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.62805124 |
| 10 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 2.33454111 |
| 11 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 2.30885080 |
| 12 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 2.23321112 |
| 13 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 2.14957039 |
| 14 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 2.07494252 |
| 15 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.97012970 |
| 16 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.93057315 |
| 17 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.91299411 |
| 18 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.86565837 |
| 19 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.86198924 |
| 20 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.81574445 |
| 21 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.74976431 |
| 22 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.71672381 |
| 23 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.69515490 |
| 24 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.69515490 |
| 25 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.69407445 |
| 26 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 1.67763444 |
| 27 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.62523216 |
| 28 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.58246336 |
| 29 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.53142512 |
| 30 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.51922592 |
| 31 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.49558389 |
| 32 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.49465518 |
| 33 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.42980419 |
| 34 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.42720889 |
| 35 | TP53_16413492_ChIP-PET_HCT116_Human | 1.41333056 |
| 36 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.40793349 |
| 37 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.38532862 |
| 38 | MYC_22102868_ChIP-Seq_BL_Human | 1.33563952 |
| 39 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.32546253 |
| 40 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.32530229 |
| 41 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.29504156 |
| 42 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.29171289 |
| 43 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.28331050 |
| 44 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.27712915 |
| 45 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.26114358 |
| 46 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.24133014 |
| 47 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.23227227 |
| 48 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.19287658 |
| 49 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.18907843 |
| 50 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.17880571 |
| 51 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.15246392 |
| 52 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.14883179 |
| 53 | GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.14716991 |
| 54 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.14235573 |
| 55 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.05134115 |
| 56 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.04837556 |
| 57 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 1.01341135 |
| 58 | LUZP1_20508642_ChIP-Seq_ESCs_Mouse | 1.01102291 |
| 59 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.99063206 |
| 60 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.98254076 |
| 61 | CBP_21632823_ChIP-Seq_H3396_Human | 0.97965314 |
| 62 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.97542518 |
| 63 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.96220748 |
| 64 | KDM2B_26808549_Chip-Seq_REH_Human | 0.95702458 |
| 65 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 0.95229823 |
| 66 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.94940569 |
| 67 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 0.93566968 |
| 68 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.93327220 |
| 69 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 0.91349444 |
| 70 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.89761355 |
| 71 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.88257679 |
| 72 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.87943750 |
| 73 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.87747384 |
| 74 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.86821256 |
| 75 | RUNX_20019798_ChIP-Seq_JUKART_Human | 0.86159348 |
| 76 | KLF4_19829295_ChIP-Seq_ESCs_Human | 0.86047082 |
| 77 | CTCF_21964334_Chip-Seq_Bcells_Human | 0.85703957 |
| 78 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 0.83569851 |
| 79 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.82924037 |
| 80 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 0.81283238 |
| 81 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.80365578 |
| 82 | MYC_27129775_Chip-Seq_CORNEA_Mouse | 0.80331736 |
| 83 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.79969665 |
| 84 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.77712751 |
| 85 | VDR_24763502_ChIP-Seq_THP-1_Human | 0.77422520 |
| 86 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 0.76103107 |
| 87 | AR_25329375_ChIP-Seq_VCAP_Human | 0.75601372 |
| 88 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 0.74845657 |
| 89 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.74711061 |
| 90 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.74649668 |
| 91 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.74114943 |
| 92 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.74097189 |
| 93 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.74054198 |
| 94 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 0.73581258 |
| 95 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.73581258 |
| 96 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 0.73581258 |
| 97 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.72814937 |
| 98 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.72142966 |
| 99 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 0.71666538 |
| 100 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 0.71621913 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003786_premature_aging | 5.42711715 |
| 2 | MP0002876_abnormal_thyroid_physiology | 4.47851899 |
| 3 | MP0002653_abnormal_ependyma_morphology | 4.14255310 |
| 4 | MP0004264_abnormal_extraembryonic_tissu | 3.46315346 |
| 5 | MP0003763_abnormal_thymus_physiology | 3.18850108 |
| 6 | MP0006082_CNS_inflammation | 2.88588795 |
| 7 | MP0005671_abnormal_response_to | 2.76567657 |
| 8 | MP0001986_abnormal_taste_sensitivity | 2.70251097 |
| 9 | MP0010094_abnormal_chromosome_stability | 2.58970179 |
| 10 | MP0004885_abnormal_endolymph | 2.22188681 |
| 11 | MP0008875_abnormal_xenobiotic_pharmacok | 2.01077871 |
| 12 | MP0008995_early_reproductive_senescence | 12.9905953 |
| 13 | MP0001849_ear_inflammation | 1.98533544 |
| 14 | MP0002132_abnormal_respiratory_system | 1.94468518 |
| 15 | MP0002127_abnormal_cardiovascular_syste | 1.79629544 |
| 16 | MP0009333_abnormal_splenocyte_physiolog | 1.79083240 |
| 17 | MP0003111_abnormal_nucleus_morphology | 1.72700614 |
| 18 | MP0004742_abnormal_vestibular_system | 1.64061050 |
| 19 | MP0002697_abnormal_eye_size | 1.61031410 |
| 20 | MP0004270_analgesia | 1.54400493 |
| 21 | MP0001119_abnormal_female_reproductive | 1.46384016 |
| 22 | MP0006276_abnormal_autonomic_nervous | 1.43154902 |
| 23 | MP0004019_abnormal_vitamin_homeostasis | 1.32921256 |
| 24 | MP0001666_abnormal_nutrient_absorption | 1.26890997 |
| 25 | MP0003699_abnormal_female_reproductive | 1.26381611 |
| 26 | MP0003936_abnormal_reproductive_system | 1.21259590 |
| 27 | MP0001881_abnormal_mammary_gland | 1.17473878 |
| 28 | MP0000566_synostosis | 1.16303023 |
| 29 | MP0001542_abnormal_bone_strength | 1.15454721 |
| 30 | MP0002398_abnormal_bone_marrow | 1.14107855 |
| 31 | MP0005085_abnormal_gallbladder_physiolo | 1.07141004 |
| 32 | MP0005025_abnormal_response_to | 1.06215623 |
| 33 | MP0001661_extended_life_span | 1.04576089 |
| 34 | MP0002837_dystrophic_cardiac_calcinosis | 1.00243159 |
| 35 | MP0002420_abnormal_adaptive_immunity | 0.97591746 |
| 36 | MP0000569_abnormal_digit_pigmentation | 0.96854199 |
| 37 | MP0009785_altered_susceptibility_to | 0.95694347 |
| 38 | MP0001790_abnormal_immune_system | 0.95069127 |
| 39 | MP0005387_immune_system_phenotype | 0.95069127 |
| 40 | MP0000716_abnormal_immune_system | 0.93949135 |
| 41 | MP0002210_abnormal_sex_determination | 0.93114056 |
| 42 | MP0002723_abnormal_immune_serum | 0.92888913 |
| 43 | MP0001819_abnormal_immune_cell | 0.91815530 |
| 44 | MP0001485_abnormal_pinna_reflex | 0.91629367 |
| 45 | MP0002429_abnormal_blood_cell | 0.85243048 |
| 46 | MP0000627_abnormal_mammary_gland | 0.76277882 |
| 47 | MP0009046_muscle_twitch | 0.73740397 |
| 48 | MP0001800_abnormal_humoral_immune | 0.71823321 |
| 49 | MP0001440_abnormal_grooming_behavior | 0.71077821 |
| 50 | MP0002734_abnormal_mechanical_nocicepti | 0.70861136 |
| 51 | MP0005000_abnormal_immune_tolerance | 0.69258515 |
| 52 | MP0003646_muscle_fatigue | 0.69135092 |
| 53 | MP0005508_abnormal_skeleton_morphology | 0.66237337 |
| 54 | MP0003866_abnormal_defecation | 0.65467177 |
| 55 | MP0005464_abnormal_platelet_physiology | 0.62485044 |
| 56 | MP0003943_abnormal_hepatobiliary_system | 0.61339996 |
| 57 | MP0001929_abnormal_gametogenesis | 0.61160894 |
| 58 | MP0002161_abnormal_fertility/fecundity | 0.59055068 |
| 59 | MP0003698_abnormal_male_reproductive | 0.59013214 |
| 60 | MP0001145_abnormal_male_reproductive | 0.58768013 |
| 61 | MP0000343_altered_response_to | 0.58415913 |
| 62 | MP0004947_skin_inflammation | 0.56915680 |
| 63 | MP0009250_abnormal_appendicular_skeleto | 0.55555863 |
| 64 | MP0002116_abnormal_craniofacial_bone | 0.55508519 |
| 65 | MP0003195_calcinosis | 0.55115968 |
| 66 | MP0000653_abnormal_sex_gland | 0.54963561 |
| 67 | MP0002736_abnormal_nociception_after | 0.52110189 |
| 68 | MP0001944_abnormal_pancreas_morphology | 0.51979096 |
| 69 | MP0005275_abnormal_skin_tensile | 0.51750663 |
| 70 | MP0000703_abnormal_thymus_morphology | 0.50208337 |
| 71 | MP0008004_abnormal_stomach_pH | 0.49021316 |
| 72 | MP0008775_abnormal_heart_ventricle | 0.48470760 |
| 73 | MP0005330_cardiomyopathy | 0.47263610 |
| 74 | MP0003136_yellow_coat_color | 0.46791871 |
| 75 | MP0002735_abnormal_chemical_nociception | 0.45947333 |
| 76 | MP0005084_abnormal_gallbladder_morpholo | 0.44098828 |
| 77 | MP0000920_abnormal_myelination | 0.43045924 |
| 78 | MP0003638_abnormal_response/metabolism_ | 0.42466920 |
| 79 | MP0009745_abnormal_behavioral_response | 0.42109969 |
| 80 | MP0003137_abnormal_impulse_conducting | 0.41814748 |
| 81 | MP0002722_abnormal_immune_system | 0.41659650 |
| 82 | MP0003632_abnormal_nervous_system | 0.41641011 |
| 83 | MP0005266_abnormal_metabolism | 0.41405279 |
| 84 | MP0005423_abnormal_somatic_nervous | 0.41260783 |
| 85 | MP0002822_catalepsy | 0.40697605 |
| 86 | MP0005332_abnormal_amino_acid | 0.39466039 |
| 87 | MP0002998_abnormal_bone_remodeling | 0.38659844 |
| 88 | MP0003880_abnormal_central_pattern | 0.38557705 |
| 89 | MP0005319_abnormal_enzyme/_coenzyme | 0.38385833 |
| 90 | MP0002088_abnormal_embryonic_growth/wei | 0.38128070 |
| 91 | MP0005377_hearing/vestibular/ear_phenot | 0.37389784 |
| 92 | MP0003878_abnormal_ear_physiology | 0.37389784 |
| 93 | MP0002277_abnormal_respiratory_mucosa | 0.36589992 |
| 94 | MP0001731_abnormal_postnatal_growth | 0.36467828 |
| 95 | MP0002064_seizures | 0.36413296 |
| 96 | MP0003283_abnormal_digestive_organ | 0.35744001 |
| 97 | MP0004142_abnormal_muscle_tone | 0.33287474 |
| 98 | MP0002452_abnormal_antigen_presenting | 0.33070068 |
| 99 | MP0002067_abnormal_sensory_capabilities | 0.32731619 |
| 100 | MP0001905_abnormal_dopamine_level | 0.32624786 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of the renal collecting system (HP:0004742) | 9.19483374 |
| 2 | Reticulocytopenia (HP:0001896) | 8.97614508 |
| 3 | Chromsome breakage (HP:0040012) | 8.89640665 |
| 4 | Abnormality of pyrimidine metabolism (HP:0004353) | 8.31501369 |
| 5 | Abnormality of DNA repair (HP:0003254) | 7.03507074 |
| 6 | Oral leukoplakia (HP:0002745) | 6.69156239 |
| 7 | Ureteral duplication (HP:0000073) | 6.43478799 |
| 8 | Aplastic anemia (HP:0001915) | 6.39656047 |
| 9 | Duplication of thumb phalanx (HP:0009942) | 5.80102149 |
| 10 | Ectopic kidney (HP:0000086) | 5.33575563 |
| 11 | Increased serum pyruvate (HP:0003542) | 4.88528733 |
| 12 | Absent thumb (HP:0009777) | 4.45592990 |
| 13 | Autoimmune thrombocytopenia (HP:0001973) | 4.32804973 |
| 14 | Abnormality of glycolysis (HP:0004366) | 4.15126094 |
| 15 | Enlarged epiphyses (HP:0010580) | 4.10189974 |
| 16 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 4.07604101 |
| 17 | Meckel diverticulum (HP:0002245) | 3.78054528 |
| 18 | Absent radius (HP:0003974) | 3.76970925 |
| 19 | Abnormality of the preputium (HP:0100587) | 3.72563677 |
| 20 | Eosinophilia (HP:0001880) | 3.62454959 |
| 21 | Aplasia involving forearm bones (HP:0009822) | 3.60430419 |
| 22 | Absent forearm bone (HP:0003953) | 3.60430419 |
| 23 | Abnormality of the ileum (HP:0001549) | 3.56489689 |
| 24 | Thyroid-stimulating hormone excess (HP:0002925) | 3.55703093 |
| 25 | Pancytopenia (HP:0001876) | 3.52297078 |
| 26 | Abnormality of B cell number (HP:0010975) | 3.46149505 |
| 27 | Abnormality of T cell number (HP:0011839) | 3.43629888 |
| 28 | Stomach cancer (HP:0012126) | 3.40645330 |
| 29 | Hypergonadotropic hypogonadism (HP:0000815) | 3.26249903 |
| 30 | Autoimmune hemolytic anemia (HP:0001890) | 3.23204732 |
| 31 | Rough bone trabeculation (HP:0100670) | 3.11892936 |
| 32 | Horseshoe kidney (HP:0000085) | 3.10165860 |
| 33 | Clubbing of toes (HP:0100760) | 3.09703133 |
| 34 | Renal cortical cysts (HP:0000803) | 3.09212573 |
| 35 | Abnormality of chromosome stability (HP:0003220) | 3.08010603 |
| 36 | Increased IgM level (HP:0003496) | 2.93029782 |
| 37 | Flattened epiphyses (HP:0003071) | 2.91644968 |
| 38 | Granulocytopenia (HP:0001913) | 2.88181344 |
| 39 | Abnormality of the carotid arteries (HP:0005344) | 2.75929289 |
| 40 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 2.73916433 |
| 41 | Abnormality of nucleobase metabolism (HP:0010932) | 2.69749897 |
| 42 | Increased hepatocellular lipid droplets (HP:0006565) | 2.60969315 |
| 43 | Joint swelling (HP:0001386) | 2.59988112 |
| 44 | Abnormality of eosinophils (HP:0001879) | 2.59700712 |
| 45 | Abnormality of reticulocytes (HP:0004312) | 2.54751096 |
| 46 | Abnormality of T cells (HP:0002843) | 2.48185075 |
| 47 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.40960374 |
| 48 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.39738739 |
| 49 | Leukopenia (HP:0001882) | 2.39548179 |
| 50 | Small intestinal stenosis (HP:0012848) | 2.39387630 |
| 51 | Duodenal stenosis (HP:0100867) | 2.39387630 |
| 52 | Bone marrow hypocellularity (HP:0005528) | 2.38767584 |
| 53 | Abnormal trabecular bone morphology (HP:0100671) | 2.36406392 |
| 54 | Neutropenia (HP:0001875) | 2.35420763 |
| 55 | Cellular immunodeficiency (HP:0005374) | 2.35017522 |
| 56 | Syringomyelia (HP:0003396) | 2.34811578 |
| 57 | Spinal cord lesions (HP:0100561) | 2.34811578 |
| 58 | Absent epiphyses (HP:0010577) | 2.27802369 |
| 59 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 2.27802369 |
| 60 | Abnormality of the vertebral endplates (HP:0005106) | 2.25446207 |
| 61 | Lipid accumulation in hepatocytes (HP:0006561) | 2.21723495 |
| 62 | Short thumb (HP:0009778) | 2.21073118 |
| 63 | Abnormality of the epiphysis of the femoral head (HP:0010574) | 2.16848043 |
| 64 | Renal Fanconi syndrome (HP:0001994) | 2.13203417 |
| 65 | Partial duplication of the phalanx of hand (HP:0009999) | 2.12062852 |
| 66 | Megalocornea (HP:0000485) | 2.05435344 |
| 67 | Duplicated collecting system (HP:0000081) | 10.3280159 |
| 68 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 10.1503003 |
| 69 | Abnormality of femoral epiphyses (HP:0006499) | 1.99971221 |
| 70 | Abnormality involving the epiphyses of the lower limbs (HP:0006500) | 1.99971221 |
| 71 | Renal agenesis (HP:0000104) | 1.99705089 |
| 72 | T lymphocytopenia (HP:0005403) | 1.98702612 |
| 73 | Abnormality of the femoral head (HP:0003368) | 1.97691814 |
| 74 | Tracheoesophageal fistula (HP:0002575) | 1.95724286 |
| 75 | Abnormality of the duodenum (HP:0002246) | 1.94225337 |
| 76 | Hypochromic anemia (HP:0001931) | 1.92974130 |
| 77 | Premature graying of hair (HP:0002216) | 1.88504229 |
| 78 | Mutism (HP:0002300) | 1.87790633 |
| 79 | Triphalangeal thumb (HP:0001199) | 1.83524855 |
| 80 | Exertional dyspnea (HP:0002875) | 1.73868837 |
| 81 | Progressive neurologic deterioration (HP:0002344) | 1.72450381 |
| 82 | Pallor (HP:0000980) | 1.66136693 |
| 83 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.65124160 |
| 84 | Disproportionate short-trunk short stature (HP:0003521) | 1.64678720 |
| 85 | Thoracic kyphosis (HP:0002942) | 1.62352334 |
| 86 | Abnormality of cochlea (HP:0000375) | 1.61155163 |
| 87 | Leukocytosis (HP:0001974) | 1.60759508 |
| 88 | Abnormality of oral frenula (HP:0000190) | 1.55803322 |
| 89 | Increased intramyocellular lipid droplets (HP:0012240) | 1.55084982 |
| 90 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.53916717 |
| 91 | Coronal craniosynostosis (HP:0004440) | 1.51309661 |
| 92 | Abnormality of the 2nd finger (HP:0004100) | 1.51254151 |
| 93 | Abnormality of the renal cortex (HP:0011035) | 1.51219206 |
| 94 | Arteriovenous malformation (HP:0100026) | 1.51127436 |
| 95 | Abnormality of the parietal bone (HP:0002696) | 1.48048534 |
| 96 | IgM deficiency (HP:0002850) | 1.46123675 |
| 97 | Nausea (HP:0002018) | 1.43965647 |
| 98 | Epiphyseal dysplasia (HP:0002656) | 1.43684103 |
| 99 | Abnormality of the phalanges of the hallux (HP:0010057) | 1.40249204 |
| 100 | Astigmatism (HP:0000483) | 1.38481950 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K1 | 7.41669523 |
| 2 | TXK | 7.37457916 |
| 3 | BCKDK | 3.71139761 |
| 4 | TAOK3 | 12.6915592 |
| 5 | ZAP70 | 1.90343308 |
| 6 | TESK2 | 1.66686070 |
| 7 | PRPF4B | 1.65780479 |
| 8 | IKBKE | 0.95055727 |
| 9 | CAMK1D | 0.89487448 |
| 10 | TESK1 | 0.82480094 |
| 11 | NLK | 0.77961820 |
| 12 | SGK1 | 0.76053908 |
| 13 | TBK1 | 0.68924759 |
| 14 | CAMK1G | 0.65508519 |
| 15 | SYK | 0.56479317 |
| 16 | ATR | 0.52793353 |
| 17 | PIK3CA | 0.50689826 |
| 18 | JAK1 | 0.49087221 |
| 19 | TYRO3 | 0.48819957 |
| 20 | LCK | 0.48305507 |
| 21 | ITK | 0.47905684 |
| 22 | LIMK1 | 0.45487655 |
| 23 | LYN | 0.42233871 |
| 24 | MAPK13 | 0.41369511 |
| 25 | HCK | 0.40743215 |
| 26 | FRK | 0.35985459 |
| 27 | IGF1R | 0.32047289 |
| 28 | TLK1 | 0.29747927 |
| 29 | INSRR | 0.28395145 |
| 30 | SGK2 | 0.28246719 |
| 31 | CSNK1G1 | 0.28125712 |
| 32 | ADRBK2 | 0.26834544 |
| 33 | PLK4 | 0.26645958 |
| 34 | IKBKB | 0.25894586 |
| 35 | MAP4K2 | 0.25657640 |
| 36 | MAPK12 | 0.25262366 |
| 37 | PRKAA2 | 0.23805595 |
| 38 | MUSK | 0.23393159 |
| 39 | OBSCN | 0.23173994 |
| 40 | ERBB2 | 0.21447639 |
| 41 | SRPK1 | 0.20666204 |
| 42 | GSK3A | 0.19173149 |
| 43 | EPHA4 | 0.18982501 |
| 44 | FYN | 0.18401893 |
| 45 | GRK1 | 0.18401736 |
| 46 | WNK3 | 0.18277929 |
| 47 | AKT2 | 0.17833735 |
| 48 | MAP3K5 | 0.17824177 |
| 49 | PRKAA1 | 0.17433404 |
| 50 | PIM1 | 0.16831186 |
| 51 | CSNK1A1 | 0.16601121 |
| 52 | TRPM7 | 0.16407234 |
| 53 | AKT1 | 0.16031005 |
| 54 | ERBB3 | 0.15275646 |
| 55 | SGK494 | 0.14117043 |
| 56 | SGK223 | 0.14117043 |
| 57 | TIE1 | 0.13658084 |
| 58 | ATM | 0.12633672 |
| 59 | GRK7 | 0.12172858 |
| 60 | MAPK15 | 0.11768907 |
| 61 | MAPK3 | 0.11683186 |
| 62 | PRKCQ | 0.11429622 |
| 63 | INSR | 0.11115500 |
| 64 | MAPKAPK2 | 0.08169125 |
| 65 | DAPK3 | 0.07621981 |
| 66 | DYRK1A | 0.07521100 |
| 67 | CAMK1 | 0.07463242 |
| 68 | BTK | 0.07398185 |
| 69 | MAPK14 | 0.07021234 |
| 70 | MELK | 0.06795956 |
| 71 | PRKCA | 0.06596776 |
| 72 | MTOR | 0.06588371 |
| 73 | ZAK | 0.06198267 |
| 74 | ADRBK1 | 0.06086108 |
| 75 | PRKCE | 0.05891074 |
| 76 | CSNK2A1 | 0.05647956 |
| 77 | PTK6 | 0.05120249 |
| 78 | CDK4 | 0.05082453 |
| 79 | RPS6KA5 | 0.04692714 |
| 80 | CAMK2A | 0.04510542 |
| 81 | ERBB4 | 0.04227383 |
| 82 | JAK3 | 0.04179515 |
| 83 | PRKCB | 0.03595670 |
| 84 | MAPK8 | 0.03535044 |
| 85 | PRKCG | 0.03189213 |
| 86 | PAK4 | 0.03133736 |
| 87 | SGK3 | 0.03101029 |
| 88 | RPS6KA4 | 0.03026740 |
| 89 | PRKACA | 0.01406223 |
| 90 | CSNK1E | 0.01256228 |
| 91 | RPS6KA1 | 0.01140700 |
| 92 | RPS6KA3 | 0.00647795 |
| 93 | PIK3CG | 0.00315981 |
| 94 | NTRK2 | -0.0213618 |
| 95 | CDK1 | -0.0173458 |
| 96 | OXSR1 | -0.0155978 |
| 97 | PTK2B | -0.0136572 |
| 98 | MATK | -0.0106727 |
| 99 | MET | -0.0053486 |
| 100 | MAPK1 | -0.0043926 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 6.28909708 |
| 2 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 3.04537894 |
| 3 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.91048365 |
| 4 | Pyruvate metabolism_Homo sapiens_hsa00620 | 2.85489636 |
| 5 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.84973914 |
| 6 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 2.65894061 |
| 7 | Allograft rejection_Homo sapiens_hsa05330 | 2.61686739 |
| 8 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.55732746 |
| 9 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.55605508 |
| 10 | Galactose metabolism_Homo sapiens_hsa00052 | 2.31640130 |
| 11 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.17630043 |
| 12 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 2.16806499 |
| 13 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 2.14200695 |
| 14 | Mismatch repair_Homo sapiens_hsa03430 | 2.04722411 |
| 15 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.97300360 |
| 16 | Asthma_Homo sapiens_hsa05310 | 1.84436906 |
| 17 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.81500095 |
| 18 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.70593867 |
| 19 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.65965129 |
| 20 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.57116994 |
| 21 | Basal transcription factors_Homo sapiens_hsa03022 | 1.53886137 |
| 22 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.51925014 |
| 23 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.43551295 |
| 24 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.42809639 |
| 25 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.42100756 |
| 26 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.41262824 |
| 27 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.31189698 |
| 28 | Viral myocarditis_Homo sapiens_hsa05416 | 1.27322704 |
| 29 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.26269541 |
| 30 | Malaria_Homo sapiens_hsa05144 | 1.25661086 |
| 31 | Parkinsons disease_Homo sapiens_hsa05012 | 1.18006336 |
| 32 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.15672983 |
| 33 | Pancreatic secretion_Homo sapiens_hsa04972 | 1.11685221 |
| 34 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.10658537 |
| 35 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.03026682 |
| 36 | Protein export_Homo sapiens_hsa03060 | 1.02746505 |
| 37 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.00379345 |
| 38 | Ribosome_Homo sapiens_hsa03010 | 0.97890654 |
| 39 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.97812816 |
| 40 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.96451475 |
| 41 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.94296788 |
| 42 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.93487759 |
| 43 | Phototransduction_Homo sapiens_hsa04744 | 0.91626500 |
| 44 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.91125564 |
| 45 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.90169444 |
| 46 | Salivary secretion_Homo sapiens_hsa04970 | 0.89744471 |
| 47 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.88411307 |
| 48 | Bile secretion_Homo sapiens_hsa04976 | 0.84558146 |
| 49 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.83320912 |
| 50 | Morphine addiction_Homo sapiens_hsa05032 | 0.80497495 |
| 51 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.78398076 |
| 52 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.75896541 |
| 53 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.75111654 |
| 54 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.71174593 |
| 55 | Platelet activation_Homo sapiens_hsa04611 | 0.69864066 |
| 56 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.67541121 |
| 57 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.66378410 |
| 58 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.66087568 |
| 59 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.65018765 |
| 60 | Olfactory transduction_Homo sapiens_hsa04740 | 0.62166238 |
| 61 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.59943247 |
| 62 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.59867859 |
| 63 | Alzheimers disease_Homo sapiens_hsa05010 | 0.59729376 |
| 64 | Leishmaniasis_Homo sapiens_hsa05140 | 0.57828105 |
| 65 | Pertussis_Homo sapiens_hsa05133 | 0.56165170 |
| 66 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.54074054 |
| 67 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.51816639 |
| 68 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.51149344 |
| 69 | Circadian entrainment_Homo sapiens_hsa04713 | 0.50318297 |
| 70 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.48360610 |
| 71 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.47719745 |
| 72 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.46806798 |
| 73 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.45047847 |
| 74 | Proteasome_Homo sapiens_hsa03050 | 0.40600193 |
| 75 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.39945400 |
| 76 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.39234549 |
| 77 | Nicotine addiction_Homo sapiens_hsa05033 | 0.38667294 |
| 78 | Taste transduction_Homo sapiens_hsa04742 | 0.38249280 |
| 79 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.37912996 |
| 80 | Huntingtons disease_Homo sapiens_hsa05016 | 0.37269375 |
| 81 | GABAergic synapse_Homo sapiens_hsa04727 | 0.35364923 |
| 82 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.34810621 |
| 83 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.34453008 |
| 84 | Retinol metabolism_Homo sapiens_hsa00830 | 0.34367596 |
| 85 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.34202236 |
| 86 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.31672149 |
| 87 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.28295229 |
| 88 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.27510891 |
| 89 | Mineral absorption_Homo sapiens_hsa04978 | 0.27187112 |
| 90 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.25926692 |
| 91 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.22455899 |
| 92 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.21631014 |
| 93 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.19290976 |
| 94 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.17775222 |
| 95 | DNA replication_Homo sapiens_hsa03030 | 0.16848930 |
| 96 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.16577989 |
| 97 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.16020964 |
| 98 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.15916570 |
| 99 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.14607058 |
| 100 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.13750550 |

