OR7E36P

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of cilium movement (GO:0003352)8.54280956
2left/right pattern formation (GO:0060972)7.33184731
3ventricular system development (GO:0021591)7.25780877
4retinal rod cell development (GO:0046548)7.04295209
5retinal cone cell development (GO:0046549)6.59779518
6microtubule bundle formation (GO:0001578)6.24254064
7left/right axis specification (GO:0070986)5.65180669
8protein neddylation (GO:0045116)5.44059140
9microtubule depolymerization (GO:0007019)5.11568129
10cilium organization (GO:0044782)5.08226567
11regulation of microtubule-based movement (GO:0060632)4.76962012
12cilium assembly (GO:0042384)4.61585055
13intraciliary transport (GO:0042073)4.48610622
14microtubule-based movement (GO:0007018)4.31921753
15regulation of integrin-mediated signaling pathway (GO:2001044)4.07151020
16cellular component assembly involved in morphogenesis (GO:0010927)4.04489101
17response to xenobiotic stimulus (GO:0009410)3.77276304
18cell projection assembly (GO:0030031)3.75004763
19microtubule polymerization or depolymerization (GO:0031109)3.66258712
20regulation of interleukin-5 production (GO:0032674)3.63751862
21neutrophil activation involved in immune response (GO:0002283)3.56270406
22photoreceptor cell maintenance (GO:0045494)3.55829936
23primary alcohol catabolic process (GO:0034310)3.53923843
24regulation of interleukin-13 production (GO:0032656)3.53362263
25lipoxygenase pathway (GO:0019372)3.52942075
26protein localization to cilium (GO:0061512)3.47170086
27phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)3.43422089
28cilium morphogenesis (GO:0060271)3.36491377
29thrombin receptor signaling pathway (GO:0070493)3.33722788
30negative regulation of protein localization to cell surface (GO:2000009)3.27939801
31vitamin transmembrane transport (GO:0035461)3.25680787
32regulation of germinal center formation (GO:0002634)3.24998447
33negative regulation of heart rate (GO:0010459)3.08623254
34sperm capacitation (GO:0048240)3.07974348
35adenosine receptor signaling pathway (GO:0001973)3.05733895
36ethanol metabolic process (GO:0006067)3.04806116
37sperm motility (GO:0030317)3.04331670
38centriole assembly (GO:0098534)3.03703431
39tolerance induction (GO:0002507)3.03403585
40triglyceride-rich lipoprotein particle remodeling (GO:0034370)3.01850168
41negative regulation of norepinephrine secretion (GO:0010700)3.00977843
42one-carbon compound transport (GO:0019755)3.00485890
43lateral ventricle development (GO:0021670)2.96807116
44negative regulation of humoral immune response (GO:0002921)2.94616553
45diterpenoid biosynthetic process (GO:0016102)2.93154982
46nucleoside diphosphate phosphorylation (GO:0006165)2.90920565
47glutathione derivative biosynthetic process (GO:1901687)2.88797505
48glutathione derivative metabolic process (GO:1901685)2.88797505
49G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.83359357
50exogenous drug catabolic process (GO:0042738)2.82573993
51regulation of platelet activation (GO:0010543)2.81500367
52regulation of platelet aggregation (GO:0090330)2.78857446
53negative regulation of response to food (GO:0032096)2.76413311
54negative regulation of appetite (GO:0032099)2.76413311
55gas transport (GO:0015669)2.76258973
56blood coagulation, intrinsic pathway (GO:0007597)2.70860655
57negative regulation of thymocyte apoptotic process (GO:0070244)2.67394892
58oxygen transport (GO:0015671)2.67142206
59negative regulation of hematopoietic progenitor cell differentiation (GO:1901533)2.66865930
60pyrimidine-containing compound transmembrane transport (GO:0072531)2.65572975
61determination of left/right symmetry (GO:0007368)2.59193064
62long-chain fatty acid biosynthetic process (GO:0042759)2.56632658
63negative regulation of platelet activation (GO:0010544)2.55394891
64hypotonic response (GO:0006971)2.55379849
65cytoplasmic microtubule organization (GO:0031122)2.55136391
66microtubule-based process (GO:0007017)2.49293712
67fusion of sperm to egg plasma membrane (GO:0007342)2.48266791
68determination of bilateral symmetry (GO:0009855)2.45646434
69androgen biosynthetic process (GO:0006702)2.43822138
70specification of symmetry (GO:0009799)2.39625657
71negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)2.39089765
72O-glycan processing (GO:0016266)2.36960883
73low-density lipoprotein particle remodeling (GO:0034374)2.34688313
74extracellular fibril organization (GO:0043206)2.32864750
75negative regulation of homotypic cell-cell adhesion (GO:0034111)2.32830810
76positive regulation of tolerance induction (GO:0002645)2.32228057
77multicellular organismal water homeostasis (GO:0050891)2.30763861
78positive regulation of endothelial cell differentiation (GO:0045603)2.30244404
79lung epithelium development (GO:0060428)2.30164323
80platelet aggregation (GO:0070527)2.29974594
81glutathione metabolic process (GO:0006749)2.27866357
82regulation of norepinephrine secretion (GO:0014061)2.27026237
83purinergic nucleotide receptor signaling pathway (GO:0035590)2.25355703
84brain morphogenesis (GO:0048854)2.24672130
85microtubule severing (GO:0051013)2.22476518
86negative regulation of macrophage derived foam cell differentiation (GO:0010745)2.20370092
87drug catabolic process (GO:0042737)2.15929301
88regulation of vacuole organization (GO:0044088)2.13355989
89reproductive system development (GO:0061458)2.12869000
90fibril organization (GO:0097435)2.12320111
91hepatocyte differentiation (GO:0070365)2.11975033
92negative regulation of heart contraction (GO:0045822)2.09455481
93negative regulation of T cell differentiation in thymus (GO:0033085)2.08859915
94cilium or flagellum-dependent cell motility (GO:0001539)18.0410322
95axonemal dynein complex assembly (GO:0070286)17.7586594
96epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)15.2942629
97cilium movement (GO:0003341)14.7715409
98motile cilium assembly (GO:0044458)14.0214868
99epithelial cilium movement (GO:0003351)12.3290517
100axoneme assembly (GO:0035082)11.5271395

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.73761591
2SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human2.92314329
3PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.56032264
4AR_21572438_ChIP-Seq_LNCaP_Human2.46238524
5FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.33621109
6TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.25672713
7BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.12172461
8ESR1_20079471_ChIP-ChIP_T-47D_Human2.10776780
9STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.09983930
10DROSHA_22980978_ChIP-Seq_HELA_Human2.06583070
11GATA1_19941826_ChIP-Seq_K562_Human1.99532033
12LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.95318517
13GATA2_19941826_ChIP-Seq_K562_Human1.85033178
14TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.84322253
15VDR_22108803_ChIP-Seq_LS180_Human1.82230163
16GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.80373924
17FOXM1_26456572_ChIP-Seq_MCF-7_Human1.76452958
18SCL_19346495_ChIP-Seq_HPC-7_Human1.72980551
19SRY_22984422_ChIP-ChIP_TESTIS_Rat1.64197901
20IGF1R_20145208_ChIP-Seq_DFB_Human1.62054902
21PIAS1_25552417_ChIP-Seq_VCAP_Human1.61476593
22ELK4_26923725_Chip-Seq_MESODERM_Mouse1.59495770
23FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.52564496
24TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.52512728
25SMAD4_21799915_ChIP-Seq_A2780_Human1.52485799
26ARNT_22903824_ChIP-Seq_MCF-7_Human1.50764193
27STAT1_20625510_ChIP-Seq_HELA_Human1.50031681
28SMRT_27268052_Chip-Seq_Bcells_Human1.49791023
29TAF15_26573619_Chip-Seq_HEK293_Human1.45238569
30STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.43492034
31ZNF217_24962896_ChIP-Seq_MCF-7_Human1.42703898
32STAT6_21828071_ChIP-Seq_BEAS2B_Human1.41481729
33GATA4_25053715_ChIP-Seq_YYC3_Human1.40651471
34TP53_16413492_ChIP-PET_HCT116_Human1.38985076
35GATA2_21666600_ChIP-Seq_HMVEC_Human1.36926949
36Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.36730993
37GATA1_19941827_ChIP-Seq_MEL_Mouse1.34831533
38SPI1_23127762_ChIP-Seq_K562_Human1.30839117
39GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.30813283
40TP63_23658742_ChIP-Seq_EP156T_Human1.28802243
41FLI1_27457419_Chip-Seq_LIVER_Mouse1.28710450
42AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.27512845
43ERG_20517297_ChIP-Seq_VCAP_Human1.23710841
44AHR_22903824_ChIP-Seq_MCF-7_Human1.23416933
45FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.22717416
46AR_20517297_ChIP-Seq_VCAP_Human1.22029251
47CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.19674344
48SOX2_20726797_ChIP-Seq_SW620_Human1.17634043
49PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.16849981
50SOX2_27498859_Chip-Seq_STOMACH_Mouse1.16795839
51GBX2_23144817_ChIP-Seq_PC3_Human1.16748474
52STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.16351242
53NR3C1_21868756_ChIP-Seq_MCF10A_Human1.16236272
54LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.16071705
55CDX2_19796622_ChIP-Seq_MESCs_Mouse1.14424466
56BCAT_22108803_ChIP-Seq_LS180_Human1.13223801
57ESR2_21235772_ChIP-Seq_MCF-7_Human1.13101892
58HTT_18923047_ChIP-ChIP_STHdh_Human1.12449042
59RBPJ_21746931_ChIP-Seq_IB4_Human1.12343633
60ESR1_21235772_ChIP-Seq_MCF-7_Human1.12071160
61CTNNB1_20460455_ChIP-Seq_HCT116_Human1.11800962
62CEBPB_22108803_ChIP-Seq_LS180_Human1.11166695
63IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.10732827
64NFYA_21822215_ChIP-Seq_K562_Human1.10607148
65KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse1.10605147
66ETV1_20927104_ChIP-Seq_GIST48_Human1.10549688
67PPAR_26484153_Chip-Seq_NCI-H1993_Human1.09732035
68TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.09411242
69TDRD3_21172665_ChIP-Seq_MCF-7_Human1.09306965
70IKZF1_21737484_ChIP-ChIP_HCT116_Human1.07876454
71EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.07789348
72AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.07467915
73STAT3_23295773_ChIP-Seq_U87_Human1.06659779
74PHF8_20622853_ChIP-Seq_HELA_Human1.06148090
75HNFA_21074721_ChIP-Seq_CACO-2_Human1.05590707
76SMAD4_21741376_ChIP-Seq_EPCs_Human1.04677764
77PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.04523040
78FOXO3_23340844_ChIP-Seq_DLD1_Human1.04460002
79TOP2B_26459242_ChIP-Seq_MCF-7_Human1.04339398
80SOX9_24532713_ChIP-Seq_HFSC_Mouse1.03652779
81PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.03600784
82TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.03501312
83HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.03204227
84CDX2_20551321_ChIP-Seq_CACO-2_Human1.02968378
85PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.02581420
86RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.01518754
87TBL1_22424771_ChIP-Seq_293T_Human1.01358343
88FOXA1_25552417_ChIP-Seq_VCAP_Human1.00181947
89SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.99586859
90NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.98913741
91NRF2_20460467_ChIP-Seq_MEFs_Mouse0.98913741
92POU3F2_20337985_ChIP-ChIP_501MEL_Human0.98352655
93NANOG_19829295_ChIP-Seq_ESCs_Human0.98317843
94SOX2_19829295_ChIP-Seq_ESCs_Human0.98317843
95GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.98238942
96SPI1_20517297_ChIP-Seq_HL60_Human0.97891529
97SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.97580053
98FOXA1_27270436_Chip-Seq_PROSTATE_Human0.96788807
99FOXA1_25329375_ChIP-Seq_VCAP_Human0.96788807
100TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.96629471

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005464_abnormal_platelet_physiology6.56654797
2MP0002653_abnormal_ependyma_morphology5.64988798
3MP0008875_abnormal_xenobiotic_pharmacok4.41075597
4MP0005083_abnormal_biliary_tract4.10531925
5MP0002132_abnormal_respiratory_system4.07105208
6MP0008004_abnormal_stomach_pH3.83245616
7MP0005623_abnormal_meninges_morphology3.07165195
8MP0009780_abnormal_chondrocyte_physiolo2.59548450
9MP0004043_abnormal_pH_regulation2.53612720
10MP0000465_gastrointestinal_hemorrhage2.50857911
11MP0000383_abnormal_hair_follicle2.37409352
12MP0001879_abnormal_lymphatic_vessel1.96369111
13MP0002277_abnormal_respiratory_mucosa1.81812977
14MP0001984_abnormal_olfaction1.71240861
15MP0001765_abnormal_ion_homeostasis1.68241174
16MP0010678_abnormal_skin_adnexa1.63598354
17MP0001835_abnormal_antigen_presentation1.62625819
18MP0003656_abnormal_erythrocyte_physiolo1.62119159
19MP0003303_peritoneal_inflammation1.60473833
20MP0003724_increased_susceptibility_to1.57235801
21MP0010155_abnormal_intestine_physiology1.57106423
22MP0008872_abnormal_physiological_respon1.56082410
23MP0004133_heterotaxia1.55179229
24MP0005253_abnormal_eye_physiology1.53796084
25MP0005377_hearing/vestibular/ear_phenot1.51518375
26MP0003878_abnormal_ear_physiology1.51518375
27MP0008789_abnormal_olfactory_epithelium1.48601977
28MP0005646_abnormal_pituitary_gland1.44601182
29MP0003566_abnormal_cell_adhesion1.38763445
30MP0005551_abnormal_eye_electrophysiolog1.36004231
31MP0005165_increased_susceptibility_to1.31693689
32MP0000343_altered_response_to1.28967550
33MP0001346_abnormal_lacrimal_gland1.28841283
34MP0000230_abnormal_systemic_arterial1.28069320
35MP0010329_abnormal_lipoprotein_level1.27789589
36MP0001663_abnormal_digestive_system1.26375792
37MP0009765_abnormal_xenobiotic_induced1.25719866
38MP0002736_abnormal_nociception_after1.21142848
39MP0009763_increased_sensitivity_to1.20420422
40MP0009643_abnormal_urine_homeostasis1.19421376
41MP0003638_abnormal_response/metabolism_1.15461474
42MP0001851_eye_inflammation1.14079843
43MP0005636_abnormal_mineral_homeostasis1.11430308
44MP0010368_abnormal_lymphatic_system1.09166630
45MP0002148_abnormal_hypersensitivity_rea1.09074914
46MP0003950_abnormal_plasma_membrane1.08976102
47MP0002160_abnormal_reproductive_system1.08863108
48MP0005410_abnormal_fertilization1.06162556
49MP0002282_abnormal_trachea_morphology1.04960907
50MP0005395_other_phenotype1.04435454
51MP0002168_other_aberrant_phenotype1.04393122
52MP0003718_maternal_effect1.00805586
53MP0005167_abnormal_blood-brain_barrier0.98206368
54MP0005085_abnormal_gallbladder_physiolo0.98100495
55MP0001790_abnormal_immune_system0.97309993
56MP0005387_immune_system_phenotype0.97309993
57MP0004215_abnormal_myocardial_fiber0.96681149
58MP0002136_abnormal_kidney_physiology0.94710819
59MP0003879_abnormal_hair_cell0.93615717
60MP0003828_pulmonary_edema0.93541948
61MP0001970_abnormal_pain_threshold0.90542177
62MP0003866_abnormal_defecation0.90225516
63MP0002735_abnormal_chemical_nociception0.84893251
64MP0004947_skin_inflammation0.84649072
65MP0001664_abnormal_digestion0.84516970
66MP0005394_taste/olfaction_phenotype0.82445698
67MP0005499_abnormal_olfactory_system0.82445698
68MP0000249_abnormal_blood_vessel0.82182769
69MP0009642_abnormal_blood_homeostasis0.82170722
70MP0005365_abnormal_bile_salt0.81664500
71MP0005084_abnormal_gallbladder_morpholo0.81641125
72MP0000858_altered_metastatic_potential0.81042581
73MP0005023_abnormal_wound_healing0.81024223
74MP0005248_abnormal_Harderian_gland0.80830061
75MP0005381_digestive/alimentary_phenotyp0.80584257
76MP0004019_abnormal_vitamin_homeostasis0.80443524
77MP0002405_respiratory_system_inflammati0.76862707
78MP0004036_abnormal_muscle_relaxation0.76346371
79MP0008961_abnormal_basal_metabolism0.75943732
80MP0005000_abnormal_immune_tolerance0.73076933
81MP0009046_muscle_twitch0.71899385
82MP0004084_abnormal_cardiac_muscle0.71534613
83MP0002733_abnormal_thermal_nociception0.70090022
84MP0005671_abnormal_response_to0.69266280
85MP0002909_abnormal_adrenal_gland0.68019201
86MP0005310_abnormal_salivary_gland0.67799186
87MP0005397_hematopoietic_system_phenotyp0.67165123
88MP0001545_abnormal_hematopoietic_system0.67165123
89MP0001666_abnormal_nutrient_absorption0.66712321
90MP0006138_congestive_heart_failure0.65656679
91MP0005164_abnormal_response_to0.64992480
92MP0005389_reproductive_system_phenotype0.63658466
93MP0006036_abnormal_mitochondrial_physio0.63497918
94MP0002118_abnormal_lipid_homeostasis0.62415533
95MP0001845_abnormal_inflammatory_respons0.61586990
96MP0001756_abnormal_urination0.61362737
97MP0001849_ear_inflammation0.61191240
98MP0002135_abnormal_kidney_morphology0.61155710
99MP0005195_abnormal_posterior_eye0.60366463
100MP0001968_abnormal_touch/_nociception0.60002719

Predicted human phenotypes

RankGene SetZ-score
1Rhinitis (HP:0012384)8.75468269
2Chronic bronchitis (HP:0004469)7.32039844
3Bronchiectasis (HP:0002110)6.61699438
4Nasal polyposis (HP:0100582)6.30411920
5Abnormality of the nasal mucosa (HP:0000433)5.18058119
6Absent rod-and cone-mediated responses on ERG (HP:0007688)4.55618517
7Bronchitis (HP:0012387)4.41354507
8Recurrent sinusitis (HP:0011108)4.08381522
9Infertility (HP:0000789)4.03629071
10Chronic sinusitis (HP:0011109)3.98562974
11Recurrent otitis media (HP:0000403)3.62527068
12Prolonged bleeding time (HP:0003010)3.52770633
13Chronic hepatic failure (HP:0100626)3.51260757
14Male infertility (HP:0003251)3.49509065
15Tubulointerstitial nephritis (HP:0001970)3.09600924
16Purpura (HP:0000979)3.07374326
17Menorrhagia (HP:0000132)3.01383332
18Hyperactive renin-angiotensin system (HP:0000841)2.87124946
19Petechiae (HP:0000967)2.76508163
20Increased mean platelet volume (HP:0011877)2.75149055
21Abnormal rod and cone electroretinograms (HP:0008323)2.70538979
22Chronic otitis media (HP:0000389)2.58923318
23Abnormal platelet volume (HP:0011876)2.52500874
24Recurrent bronchitis (HP:0002837)2.41508337
25Occipital encephalocele (HP:0002085)2.37380354
26Pancreatic fibrosis (HP:0100732)2.30336306
27Atelectasis (HP:0100750)2.24167673
28Molar tooth sign on MRI (HP:0002419)2.21700124
29Abnormality of midbrain morphology (HP:0002418)2.21700124
30True hermaphroditism (HP:0010459)2.19961807
31Epistaxis (HP:0000421)2.18712802
32Decreased circulating renin level (HP:0003351)2.15898144
33Nephronophthisis (HP:0000090)2.09840353
34Dynein arm defect of respiratory motile cilia (HP:0012255)12.3696896
35Absent/shortened dynein arms (HP:0200106)12.3696896
36Respiratory insufficiency due to defective ciliary clearance (HP:0200073)11.2741389
37Abnormal ciliary motility (HP:0012262)10.8371244
38Abnormal respiratory motile cilium morphology (HP:0005938)10.6834591
39Abnormal respiratory epithelium morphology (HP:0012253)10.6834591
40Abnormal respiratory motile cilium physiology (HP:0012261)10.3357610
41Cone-rod dystrophy (HP:0000548)1.94022857
42Bony spicule pigmentary retinopathy (HP:0007737)1.92426238
43Pancreatic cysts (HP:0001737)1.83782094
44Hyperlipoproteinemia (HP:0010980)1.82674726
45Renal salt wasting (HP:0000127)1.75740626
46Gingival bleeding (HP:0000225)1.73528904
47Abnormality of the renal medulla (HP:0100957)1.70813810
48Menstrual irregularities (HP:0000858)1.70752438
49Constricted visual fields (HP:0001133)1.68918525
50Cystic liver disease (HP:0006706)1.68812105
51Medial flaring of the eyebrow (HP:0010747)1.66115633
52Male pseudohermaphroditism (HP:0000037)1.62824257
53Dyschromatopsia (HP:0007641)1.61443416
54Impaired platelet aggregation (HP:0003540)1.57490602
55Abnormal platelet function (HP:0011869)1.57490602
56Postaxial foot polydactyly (HP:0001830)1.56499036
57Decreased central vision (HP:0007663)1.53145906
58Congenital primary aphakia (HP:0007707)1.49105803
59Hyperaldosteronism (HP:0000859)1.48693330
60Hypokalemic alkalosis (HP:0001949)1.47372627
61Congenital hepatic fibrosis (HP:0002612)1.47151242
62Progressive sensorineural hearing impairment (HP:0000408)1.44431161
63Gait imbalance (HP:0002141)1.43458200
64Tubulointerstitial abnormality (HP:0001969)1.42578638
65Nephropathy (HP:0000112)1.42433896
66Bell-shaped thorax (HP:0001591)1.41791989
67Acanthocytosis (HP:0001927)1.38524952
68Hyperkalemia (HP:0002153)1.37533606
69Portal hypertension (HP:0001409)1.35878956
70Abnormality of renin-angiotensin system (HP:0000847)1.34760369
71Nephrogenic diabetes insipidus (HP:0009806)1.30486285
72Poikilocytosis (HP:0004447)1.28046780
73Aplasia/Hypoplasia of the tongue (HP:0010295)1.26907862
74Abnormality of the hepatic vasculature (HP:0006707)1.21859400
75Anencephaly (HP:0002323)1.18617646
76Joint swelling (HP:0001386)1.18613412
77Abnormality of chloride homeostasis (HP:0011422)1.13116860
78Median cleft lip (HP:0000161)1.13098564
79Ventricular fibrillation (HP:0001663)1.12045282
80Tubular atrophy (HP:0000092)1.11234563
81Abnormality of the fingertips (HP:0001211)1.09221846
82Abnormality of the level of lipoprotein cholesterol (HP:0010979)1.08820803
83Abnormal hair whorl (HP:0010721)1.07490240
84Insulin-resistant diabetes mellitus (HP:0000831)1.07479880
85Recurrent pneumonia (HP:0006532)1.06791089
86Hyponatremia (HP:0002902)1.05366807
87Progressive hearing impairment (HP:0001730)1.04273966
88Poor coordination (HP:0002370)1.03972551
89Asplenia (HP:0001746)1.03282311
90Hypoalphalipoproteinemia (HP:0003233)1.02907083
91Supernumerary spleens (HP:0009799)1.02598445
92Postaxial hand polydactyly (HP:0001162)1.01320650
93Aortic aneurysm (HP:0004942)1.01264682
94Genital tract atresia (HP:0001827)1.00273357
95Vaginal atresia (HP:0000148)1.00198187
96Aplasia/Hypoplasia of the spleen (HP:0010451)0.99359898
97Furrowed tongue (HP:0000221)0.99290431
98Oculomotor apraxia (HP:0000657)0.97557670
99Stage 5 chronic kidney disease (HP:0003774)0.97122927
100Abnormality of sodium homeostasis (HP:0010931)0.95922026

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MST48.18796398
2MAPK157.03029452
3RIPK42.88891541
4MYLK2.63095516
5BMX2.52007068
6PTK2B2.50365796
7STK162.36303062
8MAPKAPK32.07955571
9EPHA22.04402855
10EIF2AK11.86710266
11STK241.80562432
12ZAP701.79443535
13TEC1.67056211
14BTK1.66684934
15IRAK11.66634811
16BCR1.60007676
17ERBB21.49995039
18TLK11.49375897
19ILK1.40093244
20MAP3K21.39021888
21PNCK1.29713013
22MAP3K31.29025645
23GRK61.28901889
24CSK1.26696388
25STK31.23024002
26CDK121.15461057
27GRK51.10356657
28LMTK21.04621251
29NME11.01906757
30ADRBK21.01701106
31LRRK20.96085357
32PIK3CG0.95550877
33ACVR1B0.93981198
34PAK10.93688331
35CSF1R0.93610193
36MST1R0.90656457
37TYK20.86605502
38BLK0.85272806
39SYK0.81517410
40AURKA0.80374935
41EPHA30.79512401
42STK100.79253251
43FER0.77123051
44BMPR20.77067695
45MAP3K120.74203530
46MARK20.71489851
47ADRBK10.71476838
48BMPR1B0.71035156
49PRKCI0.69412045
50TAOK10.68867075
51IKBKB0.64894831
52IRAK20.64417456
53HCK0.63507842
54PIM20.62976703
55TAOK30.60611338
56EPHB10.60269446
57TRIM280.58529239
58PRKD10.58362960
59DAPK30.57409700
60SGK20.57386203
61TRPM70.53685944
62CDC42BPA0.53496146
63FYN0.48344563
64PRKCQ0.46679118
65FGR0.45658495
66LYN0.44793180
67TNK20.43883960
68MET0.43042893
69PRKCD0.41609942
70GRK10.41262657
71MAP2K70.40893132
72MAP2K10.40815391
73ROCK10.40308606
74TESK10.37575391
75CAMK2G0.36745287
76DAPK10.32830745
77CDK80.31385664
78ITK0.30112745
79BRSK20.29715688
80MUSK0.29567856
81PAK30.28590949
82TESK20.28580322
83PRKCA0.28340590
84STK40.27914746
85PDPK10.27843288
86TTK0.27452136
87RET0.27029923
88MAP3K50.26721013
89MAP3K70.26222228
90FRK0.26081548
91MAPKAPK20.25724769
92MATK0.25550234
93IGF1R0.25539415
94PRKG10.25456420
95RPS6KA20.25239287
96PRKACG0.24146178
97PKN10.23805366
98ABL10.23187338
99CAMK2A0.23125047
100ERBB30.23028840

Predicted pathways (KEGG)

RankGene SetZ-score
1Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009804.02847350
2Drug metabolism - cytochrome P450_Homo sapiens_hsa009823.64118543
3Chemical carcinogenesis_Homo sapiens_hsa052043.43992837
4Platelet activation_Homo sapiens_hsa046112.86826865
5Pathogenic Escherichia coli infection_Homo sapiens_hsa051302.59170418
6Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.53697641
7Huntingtons disease_Homo sapiens_hsa050162.28444250
8Histidine metabolism_Homo sapiens_hsa003402.28040613
9Glutathione metabolism_Homo sapiens_hsa004802.25130657
10Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.21149715
11Hematopoietic cell lineage_Homo sapiens_hsa046402.14199134
12Phenylalanine metabolism_Homo sapiens_hsa003602.07907131
13SNARE interactions in vesicular transport_Homo sapiens_hsa041302.04614959
14Linoleic acid metabolism_Homo sapiens_hsa005912.04487265
15Tyrosine metabolism_Homo sapiens_hsa003502.03867287
16Retinol metabolism_Homo sapiens_hsa008302.02072764
17Steroid hormone biosynthesis_Homo sapiens_hsa001402.01540136
18Arachidonic acid metabolism_Homo sapiens_hsa005901.95612164
19beta-Alanine metabolism_Homo sapiens_hsa004101.85115127
20ABC transporters_Homo sapiens_hsa020101.62642794
21Pentose and glucuronate interconversions_Homo sapiens_hsa000401.59974258
22Sphingolipid metabolism_Homo sapiens_hsa006001.59287462
23Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.55102110
24Caffeine metabolism_Homo sapiens_hsa002321.52083292
25Collecting duct acid secretion_Homo sapiens_hsa049661.46959838
26Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.42877567
27ECM-receptor interaction_Homo sapiens_hsa045121.38723415
28Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.32934299
29Nitrogen metabolism_Homo sapiens_hsa009101.31059974
30Primary bile acid biosynthesis_Homo sapiens_hsa001201.24274144
31Starch and sucrose metabolism_Homo sapiens_hsa005001.22046503
32Serotonergic synapse_Homo sapiens_hsa047261.22012756
33Alcoholism_Homo sapiens_hsa050340.98138022
34alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.98110477
35Gap junction_Homo sapiens_hsa045400.97131292
36Leukocyte transendothelial migration_Homo sapiens_hsa046700.96349498
37Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.94273400
38Drug metabolism - other enzymes_Homo sapiens_hsa009830.93503663
39Circadian rhythm_Homo sapiens_hsa047100.93093089
40Systemic lupus erythematosus_Homo sapiens_hsa053220.92719953
41Olfactory transduction_Homo sapiens_hsa047400.91980402
42Chemokine signaling pathway_Homo sapiens_hsa040620.91745116
43Vascular smooth muscle contraction_Homo sapiens_hsa042700.90251424
44Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.86088016
45Endocytosis_Homo sapiens_hsa041440.82533672
46Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.77445217
47Tight junction_Homo sapiens_hsa045300.76421112
48Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.73249334
49Adherens junction_Homo sapiens_hsa045200.73152163
50Pancreatic secretion_Homo sapiens_hsa049720.72260706
51Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.71505562
52Transcriptional misregulation in cancer_Homo sapiens_hsa052020.71202496
53Regulation of actin cytoskeleton_Homo sapiens_hsa048100.66355202
54Choline metabolism in cancer_Homo sapiens_hsa052310.64822207
55Glycerolipid metabolism_Homo sapiens_hsa005610.61136901
56Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.60789877
57Salivary secretion_Homo sapiens_hsa049700.54351193
58Jak-STAT signaling pathway_Homo sapiens_hsa046300.52624699
59Notch signaling pathway_Homo sapiens_hsa043300.51484583
60Phagosome_Homo sapiens_hsa041450.49529590
61Shigellosis_Homo sapiens_hsa051310.48448877
62Calcium signaling pathway_Homo sapiens_hsa040200.48396750
63Phototransduction_Homo sapiens_hsa047440.46380470
64Peroxisome_Homo sapiens_hsa041460.45820969
65Amoebiasis_Homo sapiens_hsa051460.42851743
66Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.42372446
67Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.42252271
68Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.41869003
69Complement and coagulation cascades_Homo sapiens_hsa046100.41317936
70Glycosaminoglycan degradation_Homo sapiens_hsa005310.40181656
71Phosphatidylinositol signaling system_Homo sapiens_hsa040700.40071952
72Graft-versus-host disease_Homo sapiens_hsa053320.39756107
73Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.39494792
74Asthma_Homo sapiens_hsa053100.38032211
75Phospholipase D signaling pathway_Homo sapiens_hsa040720.37819219
76Regulation of autophagy_Homo sapiens_hsa041400.36968094
77Glycerophospholipid metabolism_Homo sapiens_hsa005640.36697410
78Allograft rejection_Homo sapiens_hsa053300.35895660
79Autoimmune thyroid disease_Homo sapiens_hsa053200.35568398
80Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.35022305
81Sulfur metabolism_Homo sapiens_hsa009200.34354106
82Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.34289919
83T cell receptor signaling pathway_Homo sapiens_hsa046600.34243536
84Rap1 signaling pathway_Homo sapiens_hsa040150.34221931
85Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.33915565
86Malaria_Homo sapiens_hsa051440.33533039
87Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.31787146
88Ras signaling pathway_Homo sapiens_hsa040140.31580947
89Circadian entrainment_Homo sapiens_hsa047130.30945033
90Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.30599487
91Focal adhesion_Homo sapiens_hsa045100.28156079
92Taste transduction_Homo sapiens_hsa047420.27475636
93B cell receptor signaling pathway_Homo sapiens_hsa046620.27346399
94Primary immunodeficiency_Homo sapiens_hsa053400.26795329
95Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.26769939
96Hepatitis C_Homo sapiens_hsa051600.23396835
97Salmonella infection_Homo sapiens_hsa051320.22929348
98Fatty acid elongation_Homo sapiens_hsa000620.22570846
99Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.22170318
100Dilated cardiomyopathy_Homo sapiens_hsa054140.22029072

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