

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | activation of protein kinase A activity (GO:0034199) | 9.89141142 |
| 2 | regulation of T-helper 2 cell differentiation (GO:0045628) | 9.87526576 |
| 3 | negative regulation of type 2 immune response (GO:0002829) | 9.81071507 |
| 4 | seminiferous tubule development (GO:0072520) | 9.59069744 |
| 5 | positive regulation of RNA splicing (GO:0033120) | 9.47954231 |
| 6 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 9.01435112 |
| 7 | cAMP biosynthetic process (GO:0006171) | 8.78075753 |
| 8 | detection of chemical stimulus involved in sensory perception (GO:0050907) | 8.46332354 |
| 9 | negative regulation of alpha-beta T cell differentiation (GO:0046639) | 8.28356382 |
| 10 | enteric nervous system development (GO:0048484) | 7.72835243 |
| 11 | regulation of protein sumoylation (GO:0033233) | 7.39739639 |
| 12 | synaptic transmission, dopaminergic (GO:0001963) | 7.19773063 |
| 13 | dendritic spine morphogenesis (GO:0060997) | 6.92342244 |
| 14 | righting reflex (GO:0060013) | 6.86966786 |
| 15 | positive regulation of mitochondrial fission (GO:0090141) | 6.67885779 |
| 16 | heterotypic cell-cell adhesion (GO:0034113) | 6.38267690 |
| 17 | positive regulation of T-helper 1 type immune response (GO:0002827) | 6.25759645 |
| 18 | hepatocyte apoptotic process (GO:0097284) | 6.08386306 |
| 19 | detection of chemical stimulus (GO:0009593) | 6.06842110 |
| 20 | endothelial cell differentiation (GO:0045446) | 5.99608427 |
| 21 | arachidonic acid secretion (GO:0050482) | 5.98231596 |
| 22 | icosanoid secretion (GO:0032309) | 5.98231596 |
| 23 | phosphatidylinositol acyl-chain remodeling (GO:0036149) | 5.79338135 |
| 24 | positive regulation of T-helper cell differentiation (GO:0045624) | 5.77560158 |
| 25 | neural tube formation (GO:0001841) | 5.18561051 |
| 26 | drug transmembrane transport (GO:0006855) | 5.18429330 |
| 27 | phosphatidylserine acyl-chain remodeling (GO:0036150) | 5.12202088 |
| 28 | regulation of mitochondrial fission (GO:0090140) | 5.01320328 |
| 29 | phosphatidylglycerol acyl-chain remodeling (GO:0036148) | 4.99155176 |
| 30 | fatty acid derivative transport (GO:1901571) | 4.92902663 |
| 31 | icosanoid transport (GO:0071715) | 4.92902663 |
| 32 | negative regulation of alpha-beta T cell activation (GO:0046636) | 4.86965038 |
| 33 | cilium or flagellum-dependent cell motility (GO:0001539) | 4.85011254 |
| 34 | neuronal ion channel clustering (GO:0045161) | 4.75188310 |
| 35 | chemosensory behavior (GO:0007635) | 4.71044342 |
| 36 | hyaluronan catabolic process (GO:0030214) | 4.60835158 |
| 37 | positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372) | 4.55207799 |
| 38 | embryonic digestive tract morphogenesis (GO:0048557) | 4.52641536 |
| 39 | regulation of T-helper 1 type immune response (GO:0002825) | 4.48530537 |
| 40 | cyclic purine nucleotide metabolic process (GO:0052652) | 4.44640656 |
| 41 | ATP hydrolysis coupled proton transport (GO:0015991) | 4.34679665 |
| 42 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 4.34679665 |
| 43 | positive regulation of membrane potential (GO:0045838) | 4.30942701 |
| 44 | cyclic nucleotide biosynthetic process (GO:0009190) | 4.30917583 |
| 45 | vocalization behavior (GO:0071625) | 4.30311195 |
| 46 | nephron tubule morphogenesis (GO:0072078) | 4.30206096 |
| 47 | nephron epithelium morphogenesis (GO:0072088) | 4.30206096 |
| 48 | attachment of spindle microtubules to kinetochore (GO:0008608) | 4.28235204 |
| 49 | retina layer formation (GO:0010842) | 4.26315079 |
| 50 | negative regulation of actin filament bundle assembly (GO:0032232) | 4.24200271 |
| 51 | regulation of T-helper cell differentiation (GO:0045622) | 4.20195550 |
| 52 | regulation of cAMP-mediated signaling (GO:0043949) | 4.15427626 |
| 53 | water transport (GO:0006833) | 4.08622115 |
| 54 | positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516) | 4.03090232 |
| 55 | dendritic spine organization (GO:0097061) | 4.01824800 |
| 56 | cellular response to glucagon stimulus (GO:0071377) | 4.01649569 |
| 57 | response to dietary excess (GO:0002021) | 4.00943881 |
| 58 | regulation of type 2 immune response (GO:0002828) | 3.99902757 |
| 59 | cAMP metabolic process (GO:0046058) | 3.99341804 |
| 60 | protein localization to synapse (GO:0035418) | 3.91797508 |
| 61 | cellular zinc ion homeostasis (GO:0006882) | 3.74555593 |
| 62 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 3.72981813 |
| 63 | negative regulation of T cell differentiation (GO:0045581) | 3.70112871 |
| 64 | monoamine transport (GO:0015844) | 3.67251466 |
| 65 | mitochondrial fusion (GO:0008053) | 3.67190814 |
| 66 | fluid transport (GO:0042044) | 3.63331431 |
| 67 | phosphatidylethanolamine acyl-chain remodeling (GO:0036152) | 3.60887300 |
| 68 | leukotriene biosynthetic process (GO:0019370) | 3.56528722 |
| 69 | drug transport (GO:0015893) | 3.53511638 |
| 70 | sequestering of metal ion (GO:0051238) | 3.51516064 |
| 71 | cellular response to ATP (GO:0071318) | 3.51053128 |
| 72 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 3.49549253 |
| 73 | positive regulation of alpha-beta T cell differentiation (GO:0046638) | 3.46551425 |
| 74 | sulfur amino acid catabolic process (GO:0000098) | 3.43579678 |
| 75 | regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370) | 3.41819129 |
| 76 | positive regulation of protein targeting to membrane (GO:0090314) | 3.39404196 |
| 77 | left/right axis specification (GO:0070986) | 3.37488086 |
| 78 | pre-miRNA processing (GO:0031054) | 3.36315616 |
| 79 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors (GO:1902043) | 3.36189621 |
| 80 | negative regulation of homotypic cell-cell adhesion (GO:0034111) | 3.32490870 |
| 81 | prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:006052 | 3.20372769 |
| 82 | renal tubule morphogenesis (GO:0061333) | 3.12715880 |
| 83 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 3.11527558 |
| 84 | phosphatidylcholine acyl-chain remodeling (GO:0036151) | 3.10937939 |
| 85 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.10484632 |
| 86 | positive regulation of dendritic spine development (GO:0060999) | 3.09290622 |
| 87 | negative regulation of astrocyte differentiation (GO:0048712) | 3.09156931 |
| 88 | positive regulation of steroid hormone secretion (GO:2000833) | 3.06822911 |
| 89 | reflex (GO:0060004) | 3.04644728 |
| 90 | adenylate cyclase-activating G-protein coupled receptor signaling pathway (GO:0007189) | 3.04033402 |
| 91 | neurofilament cytoskeleton organization (GO:0060052) | 3.03611377 |
| 92 | regulation of CD4-positive, alpha-beta T cell activation (GO:2000514) | 3.02217634 |
| 93 | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway (GO:0007193) | 3.01957700 |
| 94 | tooth mineralization (GO:0034505) | 14.1038826 |
| 95 | detection of chemical stimulus involved in sensory perception of smell (GO:0050911) | 13.6016030 |
| 96 | positive regulation of protein sumoylation (GO:0033235) | 11.7570467 |
| 97 | negative regulation of T-helper cell differentiation (GO:0045623) | 11.2245880 |
| 98 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 11.2245880 |
| 99 | protein K11-linked deubiquitination (GO:0035871) | 10.6024890 |
| 100 | regulation of T-helper 1 cell differentiation (GO:0045625) | 10.0164472 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 6.35736599 |
| 2 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 5.23379913 |
| 3 | AR_21572438_ChIP-Seq_LNCaP_Human | 4.72939564 |
| 4 | IGF1R_20145208_ChIP-Seq_DFB_Human | 4.71785417 |
| 5 | VDR_22108803_ChIP-Seq_LS180_Human | 4.41434255 |
| 6 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 3.28757580 |
| 7 | TP53_16413492_ChIP-PET_HCT116_Human | 2.09089099 |
| 8 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 2.03067209 |
| 9 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 11.6059972 |
| 10 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.91978350 |
| 11 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.91748178 |
| 12 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.91748178 |
| 13 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.85008870 |
| 14 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.78523965 |
| 15 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.76250925 |
| 16 | GATA1_19941826_ChIP-Seq_K562_Human | 1.60707132 |
| 17 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.59818443 |
| 18 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.53558620 |
| 19 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.50784981 |
| 20 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.50661423 |
| 21 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.48914044 |
| 22 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.46029077 |
| 23 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.45191742 |
| 24 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.42708216 |
| 25 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.42320408 |
| 26 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.39567409 |
| 27 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.35355926 |
| 28 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.34828799 |
| 29 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.34560923 |
| 30 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.29809304 |
| 31 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.29798662 |
| 32 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.27946539 |
| 33 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.25425523 |
| 34 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.25344947 |
| 35 | RXR_22108803_ChIP-Seq_LS180_Human | 1.24027917 |
| 36 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.23702668 |
| 37 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.20949606 |
| 38 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.20582762 |
| 39 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.19434452 |
| 40 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.16623244 |
| 41 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.13686125 |
| 42 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.09624287 |
| 43 | HNFA_21074721_ChIP-Seq_CACO-2_Human | 1.07726806 |
| 44 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.04658151 |
| 45 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 1.04159472 |
| 46 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.02729699 |
| 47 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.02612199 |
| 48 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.01920662 |
| 49 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.01572281 |
| 50 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.00946988 |
| 51 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.00441522 |
| 52 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.00198989 |
| 53 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.99870374 |
| 54 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.99739238 |
| 55 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.99701651 |
| 56 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 0.98021155 |
| 57 | TBL1_22424771_ChIP-Seq_293T_Human | 0.97148642 |
| 58 | STAT3_23295773_ChIP-Seq_U87_Human | 0.96684972 |
| 59 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 0.96669259 |
| 60 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 0.96389628 |
| 61 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.95448229 |
| 62 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.94542488 |
| 63 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.94303206 |
| 64 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 0.94302249 |
| 65 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 0.93990539 |
| 66 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.93643612 |
| 67 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.93235281 |
| 68 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.93044704 |
| 69 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.92816368 |
| 70 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 0.92726194 |
| 71 | CJUN_26792858_Chip-Seq_BT549_Human | 0.91922603 |
| 72 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 0.91733230 |
| 73 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.91519002 |
| 74 | ZNF274_21170338_ChIP-Seq_K562_Hela | 0.90285827 |
| 75 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.89176392 |
| 76 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.88674934 |
| 77 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.88536929 |
| 78 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 0.88425752 |
| 79 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.87712025 |
| 80 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 0.87178689 |
| 81 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 0.86942777 |
| 82 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.86787412 |
| 83 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.86518378 |
| 84 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.84922436 |
| 85 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.83890249 |
| 86 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 0.83477736 |
| 87 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 0.82788290 |
| 88 | NANOG_16518401_ChIP-PET_MESCs_Mouse | 0.82642133 |
| 89 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 0.82555186 |
| 90 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.79306286 |
| 91 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.78964853 |
| 92 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.78361018 |
| 93 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 0.78098400 |
| 94 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.77596965 |
| 95 | REST_21632747_ChIP-Seq_MESCs_Mouse | 0.77286115 |
| 96 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.76606673 |
| 97 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.76212850 |
| 98 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.76212850 |
| 99 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.76020507 |
| 100 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.75847291 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008961_abnormal_basal_metabolism | 9.83282570 |
| 2 | MP0004130_abnormal_muscle_cell | 4.89591119 |
| 3 | MP0004264_abnormal_extraembryonic_tissu | 3.93421173 |
| 4 | MP0003252_abnormal_bile_duct | 3.64011727 |
| 5 | MP0004133_heterotaxia | 2.72924290 |
| 6 | MP0002928_abnormal_bile_duct | 2.71727014 |
| 7 | MP0005448_abnormal_energy_balance | 2.39480100 |
| 8 | MP0006072_abnormal_retinal_apoptosis | 2.37219785 |
| 9 | MP0005408_hypopigmentation | 2.13241977 |
| 10 | MP0002751_abnormal_autonomic_nervous | 2.11121713 |
| 11 | MP0001270_distended_abdomen | 2.05664492 |
| 12 | MP0005084_abnormal_gallbladder_morpholo | 12.5902400 |
| 13 | MP0003329_amyloid_beta_deposits | 1.96195249 |
| 14 | MP0004272_abnormal_basement_membrane | 1.96069771 |
| 15 | MP0003943_abnormal_hepatobiliary_system | 1.88940710 |
| 16 | MP0005165_increased_susceptibility_to | 1.59433248 |
| 17 | MP0005220_abnormal_exocrine_pancreas | 1.57603619 |
| 18 | MP0009764_decreased_sensitivity_to | 1.51405192 |
| 19 | MP0005379_endocrine/exocrine_gland_phen | 1.48940644 |
| 20 | MP0003718_maternal_effect | 1.39305918 |
| 21 | MP0001958_emphysema | 1.37960444 |
| 22 | MP0001529_abnormal_vocalization | 1.35243753 |
| 23 | MP0000604_amyloidosis | 1.29209342 |
| 24 | MP0000465_gastrointestinal_hemorrhage | 1.11592418 |
| 25 | MP0001905_abnormal_dopamine_level | 1.10534514 |
| 26 | MP0005646_abnormal_pituitary_gland | 1.06415111 |
| 27 | MP0002572_abnormal_emotion/affect_behav | 1.04466792 |
| 28 | MP0000470_abnormal_stomach_morphology | 1.00266835 |
| 29 | MP0008569_lethality_at_weaning | 0.89158552 |
| 30 | MP0001944_abnormal_pancreas_morphology | 0.88177516 |
| 31 | MP0003638_abnormal_response/metabolism_ | 0.85419330 |
| 32 | MP0000371_diluted_coat_color | 0.85070183 |
| 33 | MP0008469_abnormal_protein_level | 0.81640861 |
| 34 | MP0002405_respiratory_system_inflammati | 0.80241795 |
| 35 | MP0002098_abnormal_vibrissa_morphology | 0.79519104 |
| 36 | MP0001800_abnormal_humoral_immune | 0.78523127 |
| 37 | MP0002909_abnormal_adrenal_gland | 0.78319593 |
| 38 | MP0003121_genomic_imprinting | 0.76957195 |
| 39 | MP0002822_catalepsy | 0.76785098 |
| 40 | MP0005253_abnormal_eye_physiology | 0.75443528 |
| 41 | MP0005164_abnormal_response_to | 0.72975243 |
| 42 | MP0003866_abnormal_defecation | 0.66840140 |
| 43 | MP0000609_abnormal_liver_physiology | 0.66696534 |
| 44 | MP0000703_abnormal_thymus_morphology | 0.66079502 |
| 45 | MP0008875_abnormal_xenobiotic_pharmacok | 0.65829318 |
| 46 | MP0002693_abnormal_pancreas_physiology | 0.65799236 |
| 47 | MP0001851_eye_inflammation | 0.64809753 |
| 48 | MP0001915_intracranial_hemorrhage | 0.64290450 |
| 49 | MP0004019_abnormal_vitamin_homeostasis | 0.61858703 |
| 50 | MP0005387_immune_system_phenotype | 0.61702450 |
| 51 | MP0001790_abnormal_immune_system | 0.61702450 |
| 52 | MP0003953_abnormal_hormone_level | 0.60537411 |
| 53 | MP0002136_abnormal_kidney_physiology | 0.59061357 |
| 54 | MP0002078_abnormal_glucose_homeostasis | 0.57842599 |
| 55 | MP0001533_abnormal_skeleton_physiology | 0.54733532 |
| 56 | MP0005551_abnormal_eye_electrophysiolog | 0.52406017 |
| 57 | MP0001845_abnormal_inflammatory_respons | 0.50040659 |
| 58 | MP0001986_abnormal_taste_sensitivity | 0.49563720 |
| 59 | MP0003195_calcinosis | 0.48595284 |
| 60 | MP0009642_abnormal_blood_homeostasis | 0.47668087 |
| 61 | MP0002722_abnormal_immune_system | 0.47263267 |
| 62 | MP0001501_abnormal_sleep_pattern | 0.46868982 |
| 63 | MP0002998_abnormal_bone_remodeling | 0.45985953 |
| 64 | MP0005645_abnormal_hypothalamus_physiol | 0.45838514 |
| 65 | MP0003880_abnormal_central_pattern | 0.45424510 |
| 66 | MP0004947_skin_inflammation | 0.43395733 |
| 67 | MP0002419_abnormal_innate_immunity | 0.39837105 |
| 68 | MP0002429_abnormal_blood_cell | 0.38617271 |
| 69 | MP0008004_abnormal_stomach_pH | 0.38434541 |
| 70 | MP0005395_other_phenotype | 0.38294310 |
| 71 | MP0002735_abnormal_chemical_nociception | 0.37662803 |
| 72 | MP0000598_abnormal_liver_morphology | 0.37113959 |
| 73 | MP0002452_abnormal_antigen_presenting | 0.37075210 |
| 74 | MP0000759_abnormal_skeletal_muscle | 0.36732578 |
| 75 | MP0005365_abnormal_bile_salt | 0.34826060 |
| 76 | MP0001299_abnormal_eye_distance/ | 0.34822406 |
| 77 | MP0001819_abnormal_immune_cell | 0.34770026 |
| 78 | MP0002420_abnormal_adaptive_immunity | 0.34690873 |
| 79 | MP0003136_yellow_coat_color | 0.34654099 |
| 80 | MP0009053_abnormal_anal_canal | 0.33676721 |
| 81 | MP0005334_abnormal_fat_pad | 0.33606622 |
| 82 | MP0000477_abnormal_intestine_morphology | 0.33405163 |
| 83 | MP0004484_altered_response_of | 0.33166127 |
| 84 | MP0002723_abnormal_immune_serum | 0.32668835 |
| 85 | MP0000716_abnormal_immune_system | 0.32361125 |
| 86 | MP0002882_abnormal_neuron_morphology | 0.32335478 |
| 87 | MP0000372_irregular_coat_pigmentation | 0.31798907 |
| 88 | MP0002229_neurodegeneration | 0.31649776 |
| 89 | MP0000920_abnormal_myelination | 0.31601077 |
| 90 | MP0009931_abnormal_skin_appearance | 0.31126307 |
| 91 | MP0006276_abnormal_autonomic_nervous | 0.29957650 |
| 92 | MP0002398_abnormal_bone_marrow | 0.29427660 |
| 93 | MP0005423_abnormal_somatic_nervous | 0.29134886 |
| 94 | MP0002396_abnormal_hematopoietic_system | 0.27553147 |
| 95 | MP0005503_abnormal_tendon_morphology | 0.27436230 |
| 96 | MP0005391_vision/eye_phenotype | 0.27405490 |
| 97 | MP0001293_anophthalmia | 0.26960160 |
| 98 | MP0000689_abnormal_spleen_morphology | 0.26218877 |
| 99 | MP0002161_abnormal_fertility/fecundity | 0.25826978 |
| 100 | MP0002736_abnormal_nociception_after | 0.25431348 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of calcium-phosphate metabolism (HP:0100530) | 9.65520211 |
| 2 | Abnormality of dental color (HP:0011073) | 8.10930253 |
| 3 | Abnormality of renal resorption (HP:0011038) | 7.87251810 |
| 4 | Polyuria (HP:0000103) | 7.81841803 |
| 5 | Osteomalacia (HP:0002749) | 7.49147823 |
| 6 | Abnormality of the dental pulp (HP:0006479) | 7.22094312 |
| 7 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 6.74024452 |
| 8 | Abnormal urine output (HP:0012590) | 6.66761342 |
| 9 | Abnormality of renal excretion (HP:0011036) | 5.80814644 |
| 10 | Round ear (HP:0100830) | 5.23444810 |
| 11 | Chronic bronchitis (HP:0004469) | 4.84326862 |
| 12 | Volvulus (HP:0002580) | 4.48382548 |
| 13 | IgM deficiency (HP:0002850) | 4.36397319 |
| 14 | Lip pit (HP:0100267) | 4.21509939 |
| 15 | Molar tooth sign on MRI (HP:0002419) | 4.09838607 |
| 16 | Abnormality of midbrain morphology (HP:0002418) | 4.09838607 |
| 17 | Toxemia of pregnancy (HP:0100603) | 4.01667641 |
| 18 | Autoimmune thrombocytopenia (HP:0001973) | 3.79716360 |
| 19 | Large earlobe (HP:0009748) | 3.67873796 |
| 20 | Esophageal varix (HP:0002040) | 3.64079455 |
| 21 | Nephrocalcinosis (HP:0000121) | 3.63940129 |
| 22 | Depressed nasal tip (HP:0000437) | 3.54014810 |
| 23 | Abnormal respiratory motile cilium physiology (HP:0012261) | 3.40639464 |
| 24 | Panhypogammaglobulinemia (HP:0003139) | 3.37681433 |
| 25 | Lipoatrophy (HP:0100578) | 3.34345434 |
| 26 | Rhinitis (HP:0012384) | 3.25725154 |
| 27 | Tachypnea (HP:0002789) | 3.18420159 |
| 28 | Drooling (HP:0002307) | 3.16828772 |
| 29 | Intestinal fistula (HP:0100819) | 3.11813722 |
| 30 | Excessive salivation (HP:0003781) | 3.02240720 |
| 31 | Nephronophthisis (HP:0000090) | 2.93562302 |
| 32 | Hypoparathyroidism (HP:0000829) | 2.93024283 |
| 33 | Sparse lateral eyebrow (HP:0005338) | 2.85962606 |
| 34 | Thick eyebrow (HP:0000574) | 2.84432117 |
| 35 | Petechiae (HP:0000967) | 2.76504765 |
| 36 | Personality changes (HP:0000751) | 2.75878952 |
| 37 | Hyperphosphaturia (HP:0003109) | 2.73460712 |
| 38 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.73308016 |
| 39 | Recurrent cutaneous fungal infections (HP:0011370) | 2.71548084 |
| 40 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.71548084 |
| 41 | Dilated cardiomyopathy (HP:0001644) | 2.55622782 |
| 42 | Abnormality of transition element cation homeostasis (HP:0011030) | 2.43992316 |
| 43 | Hepatitis (HP:0012115) | 2.40997052 |
| 44 | Nephropathy (HP:0000112) | 2.37411515 |
| 45 | Colitis (HP:0002583) | 2.36175513 |
| 46 | Short 5th finger (HP:0009237) | 2.34070695 |
| 47 | Agammaglobulinemia (HP:0004432) | 2.33675832 |
| 48 | Inability to walk (HP:0002540) | 2.31236766 |
| 49 | Ureteral stenosis (HP:0000071) | 2.29338789 |
| 50 | Glycosuria (HP:0003076) | 2.27079735 |
| 51 | Abnormality of urine glucose concentration (HP:0011016) | 2.27079735 |
| 52 | Bronchitis (HP:0012387) | 2.27038624 |
| 53 | Abnormality of the renal medulla (HP:0100957) | 2.26768359 |
| 54 | Abnormal urine phosphate concentration (HP:0012599) | 2.25723776 |
| 55 | Gingival overgrowth (HP:0000212) | 2.24947735 |
| 56 | Aplasia/Hypoplasia of the 5th finger (HP:0006262) | 2.22351555 |
| 57 | Sudden cardiac death (HP:0001645) | 2.14782132 |
| 58 | Abnormality of the fingertips (HP:0001211) | 2.13828377 |
| 59 | Preauricular pit (HP:0004467) | 2.12915834 |
| 60 | Periauricular skin pits (HP:0100277) | 2.12915834 |
| 61 | Ureteral obstruction (HP:0006000) | 2.09858239 |
| 62 | Abnormality of salivation (HP:0100755) | 2.01745246 |
| 63 | Striae distensae (HP:0001065) | 2.00779254 |
| 64 | Overgrowth (HP:0001548) | 11.6321070 |
| 65 | Amelogenesis imperfecta (HP:0000705) | 11.3864649 |
| 66 | Hypercalciuria (HP:0002150) | 1.97692456 |
| 67 | Anal stenosis (HP:0002025) | 1.97181075 |
| 68 | Recurrent otitis media (HP:0000403) | 1.96829354 |
| 69 | Decreased muscle mass (HP:0003199) | 1.95257662 |
| 70 | Ectopic kidney (HP:0000086) | 1.91084668 |
| 71 | Delayed eruption of teeth (HP:0000684) | 1.85462340 |
| 72 | Stage 5 chronic kidney disease (HP:0003774) | 1.85257018 |
| 73 | Small hand (HP:0200055) | 1.84431513 |
| 74 | Chorioretinal coloboma (HP:0000567) | 1.81884294 |
| 75 | Prominent supraorbital ridges (HP:0000336) | 1.78565569 |
| 76 | Chondrocalcinosis (HP:0000934) | 1.70805593 |
| 77 | Ectropion (HP:0000656) | 1.68309991 |
| 78 | Abnormality of Sharpey fibers (HP:0100685) | 1.67416204 |
| 79 | Skin pits (HP:0100276) | 1.66894390 |
| 80 | Preauricular skin tag (HP:0000384) | 1.66564609 |
| 81 | Oculomotor apraxia (HP:0000657) | 1.66052711 |
| 82 | Truncal ataxia (HP:0002078) | 1.65707387 |
| 83 | Bronchiectasis (HP:0002110) | 1.64913451 |
| 84 | Renal tubular dysfunction (HP:0000124) | 1.62980440 |
| 85 | Villous atrophy (HP:0011473) | 1.61127759 |
| 86 | Abnormality of small intestinal villus morphology (HP:0011472) | 1.61127759 |
| 87 | Skin tags (HP:0010609) | 1.56740911 |
| 88 | Palmoplantar keratoderma (HP:0000982) | 1.54763594 |
| 89 | Limited elbow extension (HP:0001377) | 1.54736175 |
| 90 | Blepharitis (HP:0000498) | 1.53863594 |
| 91 | Viral hepatitis (HP:0006562) | 1.52997923 |
| 92 | Polyneuropathy (HP:0001271) | 1.51028678 |
| 93 | Spontaneous abortion (HP:0005268) | 1.46495481 |
| 94 | Inflammation of the large intestine (HP:0002037) | 1.42644321 |
| 95 | Prenatal maternal abnormality (HP:0002686) | 1.40644660 |
| 96 | Highly arched eyebrow (HP:0002553) | 1.40592585 |
| 97 | Proximal placement of thumb (HP:0009623) | 1.40533736 |
| 98 | Mask-like facies (HP:0000298) | 1.40033099 |
| 99 | Abnormality of T cell physiology (HP:0011840) | 1.36453768 |
| 100 | Torticollis (HP:0000473) | 1.35116649 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K1 | 5.46383351 |
| 2 | BLK | 4.28650953 |
| 3 | STK3 | 4.19314171 |
| 4 | RIPK4 | 3.11068983 |
| 5 | CDC42BPA | 2.16432469 |
| 6 | BMPR2 | 2.02817509 |
| 7 | NTRK2 | 13.8870583 |
| 8 | INSRR | 1.25808577 |
| 9 | HIPK2 | 1.12543040 |
| 10 | MAP4K2 | 0.97874422 |
| 11 | FGFR1 | 0.87236005 |
| 12 | OBSCN | 0.75847730 |
| 13 | SYK | 0.69365834 |
| 14 | TXK | 0.69184361 |
| 15 | ROCK2 | 0.68933360 |
| 16 | PRKAA1 | 0.68820575 |
| 17 | PRKCQ | 0.63752391 |
| 18 | FRK | 0.61311416 |
| 19 | SRC | 0.60600398 |
| 20 | GRK1 | 0.57373661 |
| 21 | MUSK | 0.56450198 |
| 22 | ROCK1 | 0.53690917 |
| 23 | LATS1 | 0.52538662 |
| 24 | EPHA4 | 0.50364719 |
| 25 | GRK7 | 0.48787134 |
| 26 | WNK3 | 0.47429338 |
| 27 | KDR | 0.46749510 |
| 28 | ADRBK2 | 0.46076767 |
| 29 | TAOK3 | 0.44168036 |
| 30 | TIE1 | 0.43579310 |
| 31 | PRKACG | 0.43080433 |
| 32 | PLK4 | 0.42761029 |
| 33 | ABL1 | 0.42405690 |
| 34 | PRKACB | 0.41937948 |
| 35 | TLK1 | 0.39565731 |
| 36 | STK4 | 0.39275874 |
| 37 | PRKACA | 0.38951898 |
| 38 | CAMK2A | 0.38608619 |
| 39 | PIK3CG | 0.38066430 |
| 40 | ERBB4 | 0.35692065 |
| 41 | MAPK15 | 0.35238628 |
| 42 | PHKG2 | 0.35217528 |
| 43 | PHKG1 | 0.35217528 |
| 44 | PLK1 | 0.31503030 |
| 45 | TEC | 0.30589864 |
| 46 | BCKDK | 0.27735803 |
| 47 | GRK6 | 0.26878677 |
| 48 | LYN | 0.26713553 |
| 49 | ZAK | 0.26635282 |
| 50 | MATK | 0.25706898 |
| 51 | PRKCA | 0.25355629 |
| 52 | MAPK14 | 0.24869084 |
| 53 | GSK3B | 0.24246746 |
| 54 | RPS6KA3 | 0.22862388 |
| 55 | PRKCB | 0.22612081 |
| 56 | WEE1 | 0.21522191 |
| 57 | WNK4 | 0.19734345 |
| 58 | OXSR1 | 0.19656391 |
| 59 | ABL2 | 0.19640171 |
| 60 | GRK5 | 0.18295497 |
| 61 | MAP2K6 | 0.18259276 |
| 62 | STK39 | 0.17801344 |
| 63 | KIT | 0.17038796 |
| 64 | BTK | 0.16777152 |
| 65 | CDK1 | 0.15969188 |
| 66 | NUAK1 | 0.15338027 |
| 67 | PKN1 | 0.14019770 |
| 68 | PRKCG | 0.13696646 |
| 69 | TGFBR2 | 0.13683987 |
| 70 | MAPK13 | 0.12984303 |
| 71 | SRPK1 | 0.12494720 |
| 72 | CSNK1A1 | 0.12410397 |
| 73 | PIK3CA | 0.12029216 |
| 74 | PRKG2 | 0.12028824 |
| 75 | MST1R | 0.11936357 |
| 76 | PRKDC | 0.11346123 |
| 77 | ADRBK1 | 0.11281058 |
| 78 | ITK | 0.11151962 |
| 79 | FYN | 0.10688735 |
| 80 | LMTK2 | 0.10578371 |
| 81 | PIM2 | 0.10482806 |
| 82 | PIM1 | 0.10261900 |
| 83 | PRKCD | 0.10173340 |
| 84 | MAPK9 | 0.10085031 |
| 85 | PRKCE | 0.09882276 |
| 86 | DDR2 | 0.09591112 |
| 87 | TNK2 | 0.08679878 |
| 88 | EGFR | 0.08576297 |
| 89 | CAMK2G | 0.08548075 |
| 90 | AKT1 | 0.08529177 |
| 91 | MOS | 0.08080453 |
| 92 | LCK | 0.07968873 |
| 93 | PINK1 | 0.07938504 |
| 94 | CHUK | 0.07053024 |
| 95 | IKBKE | 0.06622933 |
| 96 | IGF1R | 0.06557824 |
| 97 | HCK | 0.06444289 |
| 98 | TTN | 0.06320298 |
| 99 | SCYL2 | 0.05377118 |
| 100 | MAPKAPK5 | 0.05320003 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Olfactory transduction_Homo sapiens_hsa04740 | 5.36349782 |
| 2 | Sulfur relay system_Homo sapiens_hsa04122 | 3.69467158 |
| 3 | Sulfur metabolism_Homo sapiens_hsa00920 | 3.63986178 |
| 4 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 3.45054316 |
| 5 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 3.23076499 |
| 6 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.98116396 |
| 7 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 2.79644245 |
| 8 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 2.73093772 |
| 9 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.53237931 |
| 10 | Bile secretion_Homo sapiens_hsa04976 | 2.33211144 |
| 11 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 2.26979362 |
| 12 | Salivary secretion_Homo sapiens_hsa04970 | 2.21775608 |
| 13 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 2.19715628 |
| 14 | Pancreatic secretion_Homo sapiens_hsa04972 | 2.18591084 |
| 15 | Gastric acid secretion_Homo sapiens_hsa04971 | 2.17747127 |
| 16 | Fat digestion and absorption_Homo sapiens_hsa04975 | 2.09028755 |
| 17 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.95281419 |
| 18 | Cocaine addiction_Homo sapiens_hsa05030 | 1.91557064 |
| 19 | Circadian entrainment_Homo sapiens_hsa04713 | 1.90050641 |
| 20 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.82026949 |
| 21 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.78876541 |
| 22 | Insulin secretion_Homo sapiens_hsa04911 | 1.77473997 |
| 23 | Taste transduction_Homo sapiens_hsa04742 | 1.74311213 |
| 24 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.69455714 |
| 25 | Morphine addiction_Homo sapiens_hsa05032 | 1.67297164 |
| 26 | GABAergic synapse_Homo sapiens_hsa04727 | 1.64899423 |
| 27 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.60845823 |
| 28 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.60285373 |
| 29 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.59900646 |
| 30 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 1.58867100 |
| 31 | Gap junction_Homo sapiens_hsa04540 | 1.52913173 |
| 32 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.49768977 |
| 33 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.45296263 |
| 34 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.42660593 |
| 35 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.37552927 |
| 36 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.34237854 |
| 37 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.29626181 |
| 38 | Melanogenesis_Homo sapiens_hsa04916 | 1.27709803 |
| 39 | Platelet activation_Homo sapiens_hsa04611 | 1.22091366 |
| 40 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.20496705 |
| 41 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.17464872 |
| 42 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.13749501 |
| 43 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.12860297 |
| 44 | Circadian rhythm_Homo sapiens_hsa04710 | 1.12110967 |
| 45 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.08437992 |
| 46 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.08033728 |
| 47 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.01788661 |
| 48 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.82109621 |
| 49 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.77433923 |
| 50 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.76610001 |
| 51 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.66155859 |
| 52 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.64641265 |
| 53 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.62990253 |
| 54 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.62429217 |
| 55 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.61998617 |
| 56 | RNA degradation_Homo sapiens_hsa03018 | 0.57929515 |
| 57 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.46998259 |
| 58 | Alcoholism_Homo sapiens_hsa05034 | 0.43528218 |
| 59 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.42689681 |
| 60 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.41889928 |
| 61 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.37340867 |
| 62 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.35806679 |
| 63 | Parkinsons disease_Homo sapiens_hsa05012 | 0.34312288 |
| 64 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.34092948 |
| 65 | Purine metabolism_Homo sapiens_hsa00230 | 0.33962619 |
| 66 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.33118387 |
| 67 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.31562438 |
| 68 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.30042922 |
| 69 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.28903865 |
| 70 | Retinol metabolism_Homo sapiens_hsa00830 | 0.28402223 |
| 71 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.25580196 |
| 72 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.25083797 |
| 73 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.20173623 |
| 74 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.19980867 |
| 75 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.18271468 |
| 76 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.17508964 |
| 77 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.16750239 |
| 78 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.14849005 |
| 79 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.14611444 |
| 80 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.14381606 |
| 81 | Prion diseases_Homo sapiens_hsa05020 | 0.13980920 |
| 82 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.13682056 |
| 83 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.12893751 |
| 84 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.11795884 |
| 85 | Phagosome_Homo sapiens_hsa04145 | 0.10570394 |
| 86 | HTLV-I infection_Homo sapiens_hsa05166 | 0.09192879 |
| 87 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.08913295 |
| 88 | Renin secretion_Homo sapiens_hsa04924 | 0.08072185 |
| 89 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.07636615 |
| 90 | Tuberculosis_Homo sapiens_hsa05152 | 0.07113352 |
| 91 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.05079824 |
| 92 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.04899470 |
| 93 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.04219552 |
| 94 | Leishmaniasis_Homo sapiens_hsa05140 | 0.03891232 |
| 95 | ABC transporters_Homo sapiens_hsa02010 | 0.03072121 |
| 96 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.02069528 |
| 97 | Asthma_Homo sapiens_hsa05310 | 0.01860526 |
| 98 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.01557451 |
| 99 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.00631949 |
| 100 | Allograft rejection_Homo sapiens_hsa05330 | 0.00328154 |

