

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | coenzyme catabolic process (GO:0009109) | 8.50753873 |
| 2 | one-carbon compound transport (GO:0019755) | 7.15804056 |
| 3 | polyol transport (GO:0015791) | 5.74833727 |
| 4 | cofactor catabolic process (GO:0051187) | 4.93596255 |
| 5 | cellular response to ATP (GO:0071318) | 4.81547718 |
| 6 | positive regulation of histone H3-K4 methylation (GO:0051571) | 4.54451224 |
| 7 | auditory receptor cell stereocilium organization (GO:0060088) | 4.43618762 |
| 8 | synapsis (GO:0007129) | 4.32322111 |
| 9 | positive regulation of gluconeogenesis (GO:0045722) | 4.06559804 |
| 10 | DNA double-strand break processing (GO:0000729) | 4.04599802 |
| 11 | phosphatidylinositol acyl-chain remodeling (GO:0036149) | 3.91023580 |
| 12 | negative regulation of macrophage differentiation (GO:0045650) | 3.82729866 |
| 13 | regulation of tyrosine phosphorylation of Stat1 protein (GO:0042510) | 3.80269318 |
| 14 | cell proliferation in forebrain (GO:0021846) | 3.78367853 |
| 15 | regulation of platelet-derived growth factor receptor signaling pathway (GO:0010640) | 3.78031248 |
| 16 | positive regulation of prostaglandin secretion (GO:0032308) | 3.77879222 |
| 17 | protein neddylation (GO:0045116) | 3.75848944 |
| 18 | regulation of DNA endoreduplication (GO:0032875) | 3.68486718 |
| 19 | regulation of cell-cell adhesion mediated by cadherin (GO:2000047) | 3.67659943 |
| 20 | detection of chemical stimulus involved in sensory perception of smell (GO:0050911) | 3.66454382 |
| 21 | negative regulation of T cell differentiation in thymus (GO:0033085) | 3.65746956 |
| 22 | forebrain morphogenesis (GO:0048853) | 3.65124545 |
| 23 | positive regulation of cAMP-mediated signaling (GO:0043950) | 3.65076072 |
| 24 | negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642) | 3.63758246 |
| 25 | regulation of prostaglandin secretion (GO:0032306) | 3.60565553 |
| 26 | spermatid nucleus differentiation (GO:0007289) | 3.60521569 |
| 27 | negative regulation of dendrite development (GO:2000171) | 3.47695411 |
| 28 | regulation of glomerulus development (GO:0090192) | 3.44077982 |
| 29 | behavioral response to nicotine (GO:0035095) | 3.41257747 |
| 30 | inner ear receptor stereocilium organization (GO:0060122) | 3.32583152 |
| 31 | nephron tubule development (GO:0072080) | 3.27392133 |
| 32 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.26626863 |
| 33 | ATP synthesis coupled proton transport (GO:0015986) | 3.26510492 |
| 34 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.26510492 |
| 35 | sulfation (GO:0051923) | 3.25823982 |
| 36 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.24990462 |
| 37 | regulation of phospholipid biosynthetic process (GO:0071071) | 3.24202751 |
| 38 | male meiosis I (GO:0007141) | 3.21617738 |
| 39 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 3.21346769 |
| 40 | GTP biosynthetic process (GO:0006183) | 3.18469504 |
| 41 | negative regulation of histone acetylation (GO:0035067) | 3.16573883 |
| 42 | rRNA modification (GO:0000154) | 3.14006184 |
| 43 | negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804) | 3.11661908 |
| 44 | regulation of cell proliferation involved in kidney development (GO:1901722) | 3.11634516 |
| 45 | phosphatidylglycerol acyl-chain remodeling (GO:0036148) | 3.11340906 |
| 46 | C-terminal protein lipidation (GO:0006501) | 3.08755161 |
| 47 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.03965706 |
| 48 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.03767526 |
| 49 | positive regulation of fatty acid transport (GO:2000193) | 3.03116313 |
| 50 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 3.02579381 |
| 51 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 3.02579381 |
| 52 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 3.02579381 |
| 53 | proteasome assembly (GO:0043248) | 2.98527222 |
| 54 | histone H3-K9 methylation (GO:0051567) | 2.97771068 |
| 55 | positive regulation of triglyceride biosynthetic process (GO:0010867) | 2.96883416 |
| 56 | detection of light stimulus involved in sensory perception (GO:0050962) | 2.94385266 |
| 57 | detection of light stimulus involved in visual perception (GO:0050908) | 2.94385266 |
| 58 | renal tubule development (GO:0061326) | 2.94359981 |
| 59 | centriole replication (GO:0007099) | 2.92407828 |
| 60 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.90639143 |
| 61 | pharyngeal system development (GO:0060037) | 2.90262911 |
| 62 | regulation of odontogenesis of dentin-containing tooth (GO:0042487) | 2.87982278 |
| 63 | rRNA methylation (GO:0031167) | 2.86650301 |
| 64 | sensory perception of smell (GO:0007608) | 2.85985277 |
| 65 | positive regulation of icosanoid secretion (GO:0032305) | 2.84950472 |
| 66 | phosphatidylserine acyl-chain remodeling (GO:0036150) | 2.83477641 |
| 67 | UTP biosynthetic process (GO:0006228) | 2.83166767 |
| 68 | purine ribonucleoside bisphosphate metabolic process (GO:0034035) | 2.82386717 |
| 69 | 3-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427) | 2.82386717 |
| 70 | regulation of cell maturation (GO:1903429) | 2.73705032 |
| 71 | flavonoid metabolic process (GO:0009812) | 2.72580646 |
| 72 | DNA deamination (GO:0045006) | 2.72401921 |
| 73 | negative regulation of lipid storage (GO:0010888) | 2.71934907 |
| 74 | regulation of acrosome reaction (GO:0060046) | 2.70746920 |
| 75 | G-protein coupled receptor internalization (GO:0002031) | 2.68510839 |
| 76 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.67300797 |
| 77 | photoreceptor cell maintenance (GO:0045494) | 2.66517507 |
| 78 | negative regulation of appetite (GO:0032099) | 2.63950995 |
| 79 | negative regulation of response to food (GO:0032096) | 2.63950995 |
| 80 | negative regulation of JAK-STAT cascade (GO:0046426) | 2.62803096 |
| 81 | oxygen transport (GO:0015671) | 2.62131505 |
| 82 | chromosome organization involved in meiosis (GO:0070192) | 2.60395948 |
| 83 | interkinetic nuclear migration (GO:0022027) | 2.60353368 |
| 84 | glycerol ether metabolic process (GO:0006662) | 2.59879697 |
| 85 | cellular ketone body metabolic process (GO:0046950) | 2.59855517 |
| 86 | dentate gyrus development (GO:0021542) | 2.58487347 |
| 87 | regulation of female receptivity (GO:0045924) | 2.58409378 |
| 88 | positive regulation of phosphoprotein phosphatase activity (GO:0032516) | 2.58376137 |
| 89 | detection of chemical stimulus involved in sensory perception (GO:0050907) | 2.57948877 |
| 90 | epithelial cell fate commitment (GO:0072148) | 2.57574638 |
| 91 | indolalkylamine metabolic process (GO:0006586) | 2.57333973 |
| 92 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.57032956 |
| 93 | negative regulation of protein acetylation (GO:1901984) | 2.55991265 |
| 94 | maturation of 5.8S rRNA (GO:0000460) | 2.55541311 |
| 95 | C-terminal protein amino acid modification (GO:0018410) | 2.55141714 |
| 96 | negative regulation of platelet activation (GO:0010544) | 2.53014198 |
| 97 | ether lipid metabolic process (GO:0046485) | 2.51948205 |
| 98 | regulation of Golgi to plasma membrane protein transport (GO:0042996) | 2.51402287 |
| 99 | regulation of stem cell maintenance (GO:2000036) | 2.50484974 |
| 100 | forebrain neuron development (GO:0021884) | 2.50392424 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 5.11205542 |
| 2 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 3.74956702 |
| 3 | VDR_22108803_ChIP-Seq_LS180_Human | 3.40829769 |
| 4 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.76170141 |
| 5 | EWS_26573619_Chip-Seq_HEK293_Human | 2.72794978 |
| 6 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.72166989 |
| 7 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.65128914 |
| 8 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.62018428 |
| 9 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.60913869 |
| 10 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.55155256 |
| 11 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.42176569 |
| 12 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.20241051 |
| 13 | IRF1_19129219_ChIP-ChIP_H3396_Human | 2.19691986 |
| 14 | FUS_26573619_Chip-Seq_HEK293_Human | 2.18884176 |
| 15 | MYC_18940864_ChIP-ChIP_HL60_Human | 2.18250786 |
| 16 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.07695448 |
| 17 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 2.06532398 |
| 18 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.05432051 |
| 19 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.99785739 |
| 20 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.99785739 |
| 21 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.90847616 |
| 22 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.87639851 |
| 23 | P300_19829295_ChIP-Seq_ESCs_Human | 1.85652990 |
| 24 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.84178297 |
| 25 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.78432254 |
| 26 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.71594006 |
| 27 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.71398156 |
| 28 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.66263327 |
| 29 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.66263327 |
| 30 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.66263327 |
| 31 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.62720985 |
| 32 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.62508041 |
| 33 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.61868807 |
| 34 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.53405151 |
| 35 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.50180640 |
| 36 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.47298421 |
| 37 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.46501824 |
| 38 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.46046676 |
| 39 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.44780240 |
| 40 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.43020319 |
| 41 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.40691489 |
| 42 | NCOR_22424771_ChIP-Seq_293T_Human | 1.40247633 |
| 43 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.37589036 |
| 44 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.36581670 |
| 45 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.35922107 |
| 46 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.33290200 |
| 47 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.30923661 |
| 48 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.29050048 |
| 49 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.28320988 |
| 50 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.27777478 |
| 51 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.26069907 |
| 52 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.24509304 |
| 53 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.24273942 |
| 54 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.23326680 |
| 55 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.22974048 |
| 56 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.22826596 |
| 57 | TCF4_23295773_ChIP-Seq_U87_Human | 1.21497612 |
| 58 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.21013485 |
| 59 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.21013485 |
| 60 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.18786778 |
| 61 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.18489371 |
| 62 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.18489371 |
| 63 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.18476829 |
| 64 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.17334631 |
| 65 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.16908103 |
| 66 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.16346269 |
| 67 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.15874311 |
| 68 | STAT3_23295773_ChIP-Seq_U87_Human | 1.15205390 |
| 69 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.13806064 |
| 70 | TP53_16413492_ChIP-PET_HCT116_Human | 1.11988238 |
| 71 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.11587114 |
| 72 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.10875798 |
| 73 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.10636480 |
| 74 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.10049332 |
| 75 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.09710605 |
| 76 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.09697432 |
| 77 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.08384990 |
| 78 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.06989916 |
| 79 | JUN_21703547_ChIP-Seq_K562_Human | 1.06083017 |
| 80 | ETV1_20927104_ChIP-Seq_GIST48_Human | 1.04798846 |
| 81 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.04419421 |
| 82 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.03660397 |
| 83 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.03129185 |
| 84 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.02636694 |
| 85 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.02216328 |
| 86 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.01040105 |
| 87 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.00758563 |
| 88 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.00517760 |
| 89 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 0.98992133 |
| 90 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.98688693 |
| 91 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.98602275 |
| 92 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.98226459 |
| 93 | ESET_19884257_ChIP-Seq_ESCs_Mouse | 0.97830391 |
| 94 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.97753083 |
| 95 | ELK1_19687146_ChIP-ChIP_HELA_Human | 0.95665093 |
| 96 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.95046802 |
| 97 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.94638728 |
| 98 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.93741579 |
| 99 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.93580573 |
| 100 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.93564975 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0004885_abnormal_endolymph | 4.30455897 |
| 2 | MP0002138_abnormal_hepatobiliary_system | 3.94944807 |
| 3 | MP0003195_calcinosis | 3.86548104 |
| 4 | MP0008057_abnormal_DNA_replication | 3.01564015 |
| 5 | MP0002160_abnormal_reproductive_system | 2.67911498 |
| 6 | MP0005410_abnormal_fertilization | 2.45385980 |
| 7 | MP0005646_abnormal_pituitary_gland | 2.37358801 |
| 8 | MP0000678_abnormal_parathyroid_gland | 2.33306013 |
| 9 | MP0005360_urolithiasis | 2.22735545 |
| 10 | MP0006292_abnormal_olfactory_placode | 2.22018185 |
| 11 | MP0004134_abnormal_chest_morphology | 2.18136454 |
| 12 | MP0009840_abnormal_foam_cell | 2.12542710 |
| 13 | MP0004147_increased_porphyrin_level | 1.95895777 |
| 14 | MP0001968_abnormal_touch/_nociception | 1.95657846 |
| 15 | MP0006276_abnormal_autonomic_nervous | 1.93901942 |
| 16 | MP0002928_abnormal_bile_duct | 1.91701562 |
| 17 | MP0002009_preneoplasia | 1.90315838 |
| 18 | MP0005389_reproductive_system_phenotype | 1.88682257 |
| 19 | MP0000566_synostosis | 1.85705108 |
| 20 | MP0001188_hyperpigmentation | 1.81452594 |
| 21 | MP0008872_abnormal_physiological_respon | 1.65012421 |
| 22 | MP0000631_abnormal_neuroendocrine_gland | 1.63471372 |
| 23 | MP0002736_abnormal_nociception_after | 1.60464881 |
| 24 | MP0005551_abnormal_eye_electrophysiolog | 1.59464112 |
| 25 | MP0000372_irregular_coat_pigmentation | 1.58918781 |
| 26 | MP0004742_abnormal_vestibular_system | 1.57579020 |
| 27 | MP0010094_abnormal_chromosome_stability | 1.57432451 |
| 28 | MP0005397_hematopoietic_system_phenotyp | 1.56330000 |
| 29 | MP0001545_abnormal_hematopoietic_system | 1.56330000 |
| 30 | MP0002139_abnormal_hepatobiliary_system | 1.55898170 |
| 31 | MP0005332_abnormal_amino_acid | 1.53618674 |
| 32 | MP0005174_abnormal_tail_pigmentation | 1.51252861 |
| 33 | MP0008877_abnormal_DNA_methylation | 1.50054744 |
| 34 | MP0005645_abnormal_hypothalamus_physiol | 1.49664234 |
| 35 | MP0001664_abnormal_digestion | 1.49397307 |
| 36 | MP0009250_abnormal_appendicular_skeleto | 1.46768633 |
| 37 | MP0002653_abnormal_ependyma_morphology | 1.46413093 |
| 38 | MP0004145_abnormal_muscle_electrophysio | 1.45492464 |
| 39 | MP0000681_abnormal_thyroid_gland | 1.44805024 |
| 40 | MP0002166_altered_tumor_susceptibility | 1.42934736 |
| 41 | MP0003950_abnormal_plasma_membrane | 1.41428821 |
| 42 | MP0003718_maternal_effect | 1.37485908 |
| 43 | MP0000049_abnormal_middle_ear | 1.34332165 |
| 44 | MP0003646_muscle_fatigue | 1.34128248 |
| 45 | MP0005084_abnormal_gallbladder_morpholo | 1.31713894 |
| 46 | MP0009780_abnormal_chondrocyte_physiolo | 1.31223296 |
| 47 | MP0008007_abnormal_cellular_replicative | 1.27353977 |
| 48 | MP0002734_abnormal_mechanical_nocicepti | 1.26949359 |
| 49 | MP0009278_abnormal_bone_marrow | 1.25560000 |
| 50 | MP0003880_abnormal_central_pattern | 1.24655744 |
| 51 | MP0002876_abnormal_thyroid_physiology | 1.23921183 |
| 52 | MP0005367_renal/urinary_system_phenotyp | 1.20262828 |
| 53 | MP0000516_abnormal_urinary_system | 1.20262828 |
| 54 | MP0003186_abnormal_redox_activity | 1.19717361 |
| 55 | MP0005365_abnormal_bile_salt | 1.18391983 |
| 56 | MP0001919_abnormal_reproductive_system | 1.14258316 |
| 57 | MP0005220_abnormal_exocrine_pancreas | 1.13466752 |
| 58 | MP0002735_abnormal_chemical_nociception | 1.11189320 |
| 59 | MP0004484_altered_response_of | 1.11114619 |
| 60 | MP0001485_abnormal_pinna_reflex | 1.10237410 |
| 61 | MP0004215_abnormal_myocardial_fiber | 1.09329936 |
| 62 | MP0002837_dystrophic_cardiac_calcinosis | 1.09293252 |
| 63 | MP0001929_abnormal_gametogenesis | 1.09206079 |
| 64 | MP0008995_early_reproductive_senescence | 1.07174056 |
| 65 | MP0009697_abnormal_copulation | 1.06154313 |
| 66 | MP0003183_abnormal_peptide_metabolism | 1.03911177 |
| 67 | MP0005253_abnormal_eye_physiology | 1.03805525 |
| 68 | MP0002272_abnormal_nervous_system | 1.02846015 |
| 69 | MP0002163_abnormal_gland_morphology | 1.01579750 |
| 70 | MP0003638_abnormal_response/metabolism_ | 0.99754315 |
| 71 | MP0003698_abnormal_male_reproductive | 0.98016166 |
| 72 | MP0002006_tumorigenesis | 0.92282684 |
| 73 | MP0009745_abnormal_behavioral_response | 0.90461637 |
| 74 | MP0000470_abnormal_stomach_morphology | 0.88043625 |
| 75 | MP0001970_abnormal_pain_threshold | 0.85736246 |
| 76 | MP0002909_abnormal_adrenal_gland | 0.85661189 |
| 77 | MP0000613_abnormal_salivary_gland | 0.85047965 |
| 78 | MP0002210_abnormal_sex_determination | 0.83959907 |
| 79 | MP0002234_abnormal_pharynx_morphology | 0.83215962 |
| 80 | MP0001270_distended_abdomen | 0.82364108 |
| 81 | MP0003787_abnormal_imprinting | 0.80914609 |
| 82 | MP0006072_abnormal_retinal_apoptosis | 0.80805659 |
| 83 | MP0005448_abnormal_energy_balance | 0.80716140 |
| 84 | MP0001944_abnormal_pancreas_morphology | 0.79210334 |
| 85 | MP0001905_abnormal_dopamine_level | 0.78899153 |
| 86 | MP0001145_abnormal_male_reproductive | 0.78834284 |
| 87 | MP0001879_abnormal_lymphatic_vessel | 0.78788380 |
| 88 | MP0002132_abnormal_respiratory_system | 0.78215622 |
| 89 | MP0001963_abnormal_hearing_physiology | 0.76727593 |
| 90 | MP0001502_abnormal_circadian_rhythm | 0.74502010 |
| 91 | MP0003937_abnormal_limbs/digits/tail_de | 0.73919066 |
| 92 | MP0000653_abnormal_sex_gland | 0.73817280 |
| 93 | MP0002733_abnormal_thermal_nociception | 0.73691616 |
| 94 | MP0010678_abnormal_skin_adnexa | 0.72674180 |
| 95 | MP0003252_abnormal_bile_duct | 0.72396876 |
| 96 | MP0000538_abnormal_urinary_bladder | 0.72110086 |
| 97 | MP0001119_abnormal_female_reproductive | 0.69767316 |
| 98 | MP0005075_abnormal_melanosome_morpholog | 0.69288957 |
| 99 | MP0002938_white_spotting | 0.69219001 |
| 100 | MP0000383_abnormal_hair_follicle | 0.68322999 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 8.21934242 |
| 2 | Absent/shortened dynein arms (HP:0200106) | 7.01748766 |
| 3 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 7.01748766 |
| 4 | Decreased central vision (HP:0007663) | 6.68868545 |
| 5 | Abnormal rod and cone electroretinograms (HP:0008323) | 5.70033198 |
| 6 | Bony spicule pigmentary retinopathy (HP:0007737) | 4.57537683 |
| 7 | Attenuation of retinal blood vessels (HP:0007843) | 4.12903831 |
| 8 | Abnormal ciliary motility (HP:0012262) | 3.84907673 |
| 9 | Constricted visual fields (HP:0001133) | 3.65601909 |
| 10 | Pendular nystagmus (HP:0012043) | 3.61018369 |
| 11 | Abnormal respiratory motile cilium morphology (HP:0005938) | 3.58864968 |
| 12 | Abnormal respiratory epithelium morphology (HP:0012253) | 3.58864968 |
| 13 | Type II lissencephaly (HP:0007260) | 3.50471935 |
| 14 | Conjunctival hamartoma (HP:0100780) | 3.47590190 |
| 15 | Abolished electroretinogram (ERG) (HP:0000550) | 3.43906606 |
| 16 | Pancreatic cysts (HP:0001737) | 3.25759316 |
| 17 | Abnormal respiratory motile cilium physiology (HP:0012261) | 3.22069833 |
| 18 | Hyperglycinuria (HP:0003108) | 3.18450755 |
| 19 | True hermaphroditism (HP:0010459) | 3.16690408 |
| 20 | Pancreatic fibrosis (HP:0100732) | 3.10038036 |
| 21 | 3-Methylglutaconic aciduria (HP:0003535) | 3.02560351 |
| 22 | Keratoconus (HP:0000563) | 2.95643032 |
| 23 | Increased corneal curvature (HP:0100692) | 2.95643032 |
| 24 | Renal cortical cysts (HP:0000803) | 2.84282609 |
| 25 | Abnormal biliary tract physiology (HP:0012439) | 2.82819104 |
| 26 | Bile duct proliferation (HP:0001408) | 2.82819104 |
| 27 | Furrowed tongue (HP:0000221) | 2.72292109 |
| 28 | Abnormality of cochlea (HP:0000375) | 2.63946570 |
| 29 | Abnormality of the renal cortex (HP:0011035) | 2.62815730 |
| 30 | Molar tooth sign on MRI (HP:0002419) | 2.53689153 |
| 31 | Abnormality of midbrain morphology (HP:0002418) | 2.53689153 |
| 32 | Goiter (HP:0000853) | 2.45489108 |
| 33 | Generalized aminoaciduria (HP:0002909) | 2.42668932 |
| 34 | Methylmalonic acidemia (HP:0002912) | 2.40075435 |
| 35 | Chorioretinal atrophy (HP:0000533) | 2.39614128 |
| 36 | Progressive macrocephaly (HP:0004481) | 2.38855879 |
| 37 | Congenital stationary night blindness (HP:0007642) | 2.38270960 |
| 38 | Acute encephalopathy (HP:0006846) | 2.38159348 |
| 39 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 2.33330790 |
| 40 | Confusion (HP:0001289) | 2.30476290 |
| 41 | Hypoplasia of the uterus (HP:0000013) | 2.26959947 |
| 42 | Bone cyst (HP:0012062) | 2.26060693 |
| 43 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.21240776 |
| 44 | Abnormality of glycine metabolism (HP:0010895) | 2.21071114 |
| 45 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.21071114 |
| 46 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.20066119 |
| 47 | Hamartoma of the eye (HP:0010568) | 2.17544280 |
| 48 | Hyperthyroidism (HP:0000836) | 2.15888445 |
| 49 | Nephronophthisis (HP:0000090) | 2.15421186 |
| 50 | Cystic liver disease (HP:0006706) | 2.10470941 |
| 51 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 2.08667194 |
| 52 | Abnormality of the nasal septum (HP:0000419) | 2.08565583 |
| 53 | Cerebral edema (HP:0002181) | 2.07425502 |
| 54 | Abnormal hemoglobin (HP:0011902) | 2.06396081 |
| 55 | Neoplasm of the adrenal cortex (HP:0100641) | 2.05091327 |
| 56 | Morphological abnormality of the inner ear (HP:0011390) | 2.05079458 |
| 57 | Severe visual impairment (HP:0001141) | 2.04522108 |
| 58 | Acute necrotizing encephalopathy (HP:0006965) | 2.03789172 |
| 59 | Respiratory difficulties (HP:0002880) | 2.02959012 |
| 60 | Supernumerary spleens (HP:0009799) | 1.98769410 |
| 61 | Hemiparesis (HP:0001269) | 1.97962581 |
| 62 | Absent thumb (HP:0009777) | 1.94502705 |
| 63 | Abnormality of the renal medulla (HP:0100957) | 1.91735454 |
| 64 | Methylmalonic aciduria (HP:0012120) | 1.83654398 |
| 65 | Lissencephaly (HP:0001339) | 1.79760185 |
| 66 | Male pseudohermaphroditism (HP:0000037) | 1.79183113 |
| 67 | Gonadal dysgenesis (HP:0000133) | 1.78340901 |
| 68 | Abnormal drinking behavior (HP:0030082) | 1.77173039 |
| 69 | Polydipsia (HP:0001959) | 1.77173039 |
| 70 | Abnormality of the fingertips (HP:0001211) | 1.76299133 |
| 71 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.76176094 |
| 72 | Dicarboxylic aciduria (HP:0003215) | 1.76176094 |
| 73 | Abnormality of urine glucose concentration (HP:0011016) | 1.73223054 |
| 74 | Glycosuria (HP:0003076) | 1.73223054 |
| 75 | Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161) | 1.72512630 |
| 76 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.72327739 |
| 77 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.71844971 |
| 78 | Abnormal biliary tract morphology (HP:0012440) | 1.71170141 |
| 79 | Abnormality of macular pigmentation (HP:0008002) | 1.70511902 |
| 80 | Optic nerve hypoplasia (HP:0000609) | 1.70018302 |
| 81 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 1.69541359 |
| 82 | Neoplasm of head and neck (HP:0012288) | 1.68213935 |
| 83 | Esophageal neoplasm (HP:0100751) | 1.68213935 |
| 84 | Recurrent sinusitis (HP:0011108) | 1.67850052 |
| 85 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.67106843 |
| 86 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.66848263 |
| 87 | Stenosis of the external auditory canal (HP:0000402) | 1.64419359 |
| 88 | Sclerocornea (HP:0000647) | 1.64299311 |
| 89 | Abnormality of chromosome stability (HP:0003220) | 1.62955369 |
| 90 | Lymphangioma (HP:0100764) | 1.62789328 |
| 91 | Abnormality of vitamin B metabolism (HP:0004340) | 1.62152056 |
| 92 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 1.60632610 |
| 93 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.60058690 |
| 94 | Volvulus (HP:0002580) | 1.58452051 |
| 95 | Meningioma (HP:0002858) | 1.58311695 |
| 96 | Gonadotropin excess (HP:0000837) | 1.57079890 |
| 97 | Long nose (HP:0003189) | 1.56672364 |
| 98 | Lip pit (HP:0100267) | 1.55669222 |
| 99 | Calf muscle hypertrophy (HP:0008981) | 1.55203182 |
| 100 | Asplenia (HP:0001746) | 1.52736446 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP3K9 | 6.55077793 |
| 2 | FRK | 6.53974566 |
| 3 | TAF1 | 3.84814567 |
| 4 | CDK19 | 2.90254877 |
| 5 | NUAK1 | 2.46069006 |
| 6 | GRK1 | 2.25893155 |
| 7 | VRK2 | 2.09710492 |
| 8 | MARK1 | 1.95890175 |
| 9 | CASK | 1.85660968 |
| 10 | MATK | 1.85312931 |
| 11 | ADRBK2 | 1.74752842 |
| 12 | KIT | 1.71719527 |
| 13 | AKT3 | 1.67625050 |
| 14 | FGFR2 | 1.64926469 |
| 15 | MAP4K2 | 1.64610353 |
| 16 | BMPR1B | 1.61015393 |
| 17 | TNIK | 1.55690639 |
| 18 | TAOK3 | 1.44096589 |
| 19 | PIK3CG | 1.42918599 |
| 20 | PLK4 | 1.38739142 |
| 21 | EIF2AK1 | 1.33254796 |
| 22 | INSRR | 1.32805547 |
| 23 | PRKG2 | 1.26521660 |
| 24 | NEK2 | 1.26161923 |
| 25 | MAP3K13 | 1.20252009 |
| 26 | CAMK1D | 1.18498251 |
| 27 | OXSR1 | 1.18320155 |
| 28 | VRK1 | 1.15947903 |
| 29 | CAMK1G | 1.14547045 |
| 30 | EIF2AK3 | 1.11791771 |
| 31 | CHEK2 | 1.10149505 |
| 32 | PRKD2 | 1.03638929 |
| 33 | ZAK | 1.03355326 |
| 34 | PINK1 | 1.02054393 |
| 35 | DAPK2 | 1.00344033 |
| 36 | CSNK1G3 | 0.91818832 |
| 37 | DAPK1 | 0.82239971 |
| 38 | PLK2 | 0.81767432 |
| 39 | JAK3 | 0.79823923 |
| 40 | BUB1 | 0.78303820 |
| 41 | MAPKAPK5 | 0.77014592 |
| 42 | CSNK1G2 | 0.76306858 |
| 43 | WNK3 | 0.76215055 |
| 44 | GRK5 | 0.75316355 |
| 45 | PLK3 | 0.75012060 |
| 46 | ILK | 0.74050269 |
| 47 | CSNK1G1 | 0.72108996 |
| 48 | TRPM7 | 0.68188704 |
| 49 | RPS6KB1 | 0.67622747 |
| 50 | STK39 | 0.66165103 |
| 51 | FLT3 | 0.66113379 |
| 52 | MAP3K4 | 0.65211696 |
| 53 | ACVR1B | 0.63870244 |
| 54 | CSNK1A1L | 0.60331112 |
| 55 | SGK2 | 0.60308257 |
| 56 | PRKCQ | 0.57081171 |
| 57 | WNK4 | 0.56452408 |
| 58 | PLK1 | 0.53116849 |
| 59 | NTRK3 | 0.51776434 |
| 60 | MST4 | 0.50720870 |
| 61 | FGFR3 | 0.49851240 |
| 62 | CDC7 | 0.49509185 |
| 63 | DAPK3 | 0.49412901 |
| 64 | MAP2K3 | 0.48877860 |
| 65 | IRAK4 | 0.48068240 |
| 66 | CDK9 | 0.47105844 |
| 67 | TEC | 0.45835323 |
| 68 | ADRBK1 | 0.45180589 |
| 69 | MAP3K3 | 0.42875819 |
| 70 | ATM | 0.42710149 |
| 71 | MAPK4 | 0.42594337 |
| 72 | PRKCH | 0.42580114 |
| 73 | EIF2AK2 | 0.42117384 |
| 74 | PBK | 0.41933125 |
| 75 | TXK | 0.40843833 |
| 76 | MAP2K1 | 0.40674587 |
| 77 | RPS6KA6 | 0.39847027 |
| 78 | SMG1 | 0.39118352 |
| 79 | IRAK1 | 0.37669888 |
| 80 | CAMK1 | 0.36919024 |
| 81 | PRKCZ | 0.36460440 |
| 82 | RPS6KA5 | 0.36351095 |
| 83 | PRKG1 | 0.35819105 |
| 84 | PRKCE | 0.35381037 |
| 85 | MAP2K6 | 0.34011420 |
| 86 | TIE1 | 0.33553624 |
| 87 | CSNK2A2 | 0.33354949 |
| 88 | PRKCA | 0.33326615 |
| 89 | NTRK2 | 0.33208100 |
| 90 | AURKA | 0.33204616 |
| 91 | MAPK13 | 0.31403714 |
| 92 | PRKACA | 0.30120935 |
| 93 | ERBB3 | 0.29430041 |
| 94 | TLK1 | 0.28755185 |
| 95 | PRKACG | 0.28426641 |
| 96 | OBSCN | 0.28323101 |
| 97 | PNCK | 0.27018821 |
| 98 | STK3 | 0.26991900 |
| 99 | PRKCI | 0.26861519 |
| 100 | STK11 | 0.26274697 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 3.47431611 |
| 2 | Sulfur metabolism_Homo sapiens_hsa00920 | 3.34276855 |
| 3 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 2.95372633 |
| 4 | Homologous recombination_Homo sapiens_hsa03440 | 2.91331368 |
| 5 | Olfactory transduction_Homo sapiens_hsa04740 | 2.66799521 |
| 6 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.59618830 |
| 7 | Basal transcription factors_Homo sapiens_hsa03022 | 2.54867733 |
| 8 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 2.43564802 |
| 9 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 2.40031726 |
| 10 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.25547492 |
| 11 | Ribosome_Homo sapiens_hsa03010 | 2.18409941 |
| 12 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.14088227 |
| 13 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.96876969 |
| 14 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.91923177 |
| 15 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.91453009 |
| 16 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.73948136 |
| 17 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.71848624 |
| 18 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.71803329 |
| 19 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.70631664 |
| 20 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.66442341 |
| 21 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.64809715 |
| 22 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.61085640 |
| 23 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.56618150 |
| 24 | Sulfur relay system_Homo sapiens_hsa04122 | 1.55831356 |
| 25 | Retinol metabolism_Homo sapiens_hsa00830 | 1.54557023 |
| 26 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.51003355 |
| 27 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.41846600 |
| 28 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.38135958 |
| 29 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.37456507 |
| 30 | Phototransduction_Homo sapiens_hsa04744 | 1.34651402 |
| 31 | Parkinsons disease_Homo sapiens_hsa05012 | 1.33728623 |
| 32 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.32480542 |
| 33 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.32355928 |
| 34 | Peroxisome_Homo sapiens_hsa04146 | 1.28580966 |
| 35 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.25736440 |
| 36 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.23612878 |
| 37 | Asthma_Homo sapiens_hsa05310 | 1.22687973 |
| 38 | RNA polymerase_Homo sapiens_hsa03020 | 1.22478894 |
| 39 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.19977070 |
| 40 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.11372186 |
| 41 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.06091764 |
| 42 | Taste transduction_Homo sapiens_hsa04742 | 1.05274496 |
| 43 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.04697717 |
| 44 | Protein export_Homo sapiens_hsa03060 | 0.98642747 |
| 45 | Renin secretion_Homo sapiens_hsa04924 | 0.94822902 |
| 46 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.93221912 |
| 47 | Nicotine addiction_Homo sapiens_hsa05033 | 0.92691671 |
| 48 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.92336545 |
| 49 | RNA transport_Homo sapiens_hsa03013 | 0.92103982 |
| 50 | RNA degradation_Homo sapiens_hsa03018 | 0.87854315 |
| 51 | Melanoma_Homo sapiens_hsa05218 | 0.86939433 |
| 52 | Alzheimers disease_Homo sapiens_hsa05010 | 0.86442738 |
| 53 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.80803422 |
| 54 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.77040991 |
| 55 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.76639491 |
| 56 | Huntingtons disease_Homo sapiens_hsa05016 | 0.75131092 |
| 57 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.73664887 |
| 58 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.72250437 |
| 59 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.69649750 |
| 60 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.67433626 |
| 61 | ABC transporters_Homo sapiens_hsa02010 | 0.65027397 |
| 62 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.64817410 |
| 63 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.64648041 |
| 64 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.62631392 |
| 65 | Morphine addiction_Homo sapiens_hsa05032 | 0.59258953 |
| 66 | Salivary secretion_Homo sapiens_hsa04970 | 0.57646979 |
| 67 | Circadian entrainment_Homo sapiens_hsa04713 | 0.57037713 |
| 68 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.57030734 |
| 69 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.55864967 |
| 70 | Insulin secretion_Homo sapiens_hsa04911 | 0.55362166 |
| 71 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.54959168 |
| 72 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.53998952 |
| 73 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.53026962 |
| 74 | Metabolic pathways_Homo sapiens_hsa01100 | 0.51122005 |
| 75 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.51079099 |
| 76 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.48672426 |
| 77 | Mismatch repair_Homo sapiens_hsa03430 | 0.48111988 |
| 78 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.47001920 |
| 79 | DNA replication_Homo sapiens_hsa03030 | 0.45933020 |
| 80 | Proteasome_Homo sapiens_hsa03050 | 0.44279262 |
| 81 | Long-term depression_Homo sapiens_hsa04730 | 0.43091753 |
| 82 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.42405091 |
| 83 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.42018523 |
| 84 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.40887573 |
| 85 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.40397584 |
| 86 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.40148022 |
| 87 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.38188943 |
| 88 | Purine metabolism_Homo sapiens_hsa00230 | 0.35432910 |
| 89 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.34733535 |
| 90 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.31891310 |
| 91 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.30479945 |
| 92 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.29812604 |
| 93 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.29146220 |
| 94 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.29097706 |
| 95 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.28997210 |
| 96 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.28276743 |
| 97 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.28255119 |
| 98 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.27706134 |
| 99 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.27130440 |
| 100 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.25665316 |

