

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | retinal ganglion cell axon guidance (GO:0031290) | 7.28595776 |
| 2 | cell wall macromolecule catabolic process (GO:0016998) | 6.87721927 |
| 3 | positive regulation of protein deacetylation (GO:0090312) | 6.80887026 |
| 4 | negative regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043518) | 6.40251801 |
| 5 | neurotransmitter-gated ion channel clustering (GO:0072578) | 5.94999710 |
| 6 | RNA destabilization (GO:0050779) | 5.79182499 |
| 7 | cell wall macromolecule metabolic process (GO:0044036) | 5.77750409 |
| 8 | protein localization to cilium (GO:0061512) | 5.73040528 |
| 9 | cellular ketone body metabolic process (GO:0046950) | 5.70350683 |
| 10 | somite rostral/caudal axis specification (GO:0032525) | 5.60337516 |
| 11 | detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580) | 5.52179757 |
| 12 | forebrain neuron development (GO:0021884) | 5.44041559 |
| 13 | cholesterol biosynthetic process (GO:0006695) | 5.14162591 |
| 14 | neuronal stem cell maintenance (GO:0097150) | 5.12189022 |
| 15 | ketone body metabolic process (GO:1902224) | 5.07303754 |
| 16 | response to folic acid (GO:0051593) | 4.92233770 |
| 17 | positive regulation of action potential (GO:0045760) | 4.88071321 |
| 18 | exploration behavior (GO:0035640) | 4.80947288 |
| 19 | membrane budding (GO:0006900) | 4.79602180 |
| 20 | detection of chemical stimulus involved in sensory perception of taste (GO:0050912) | 4.73221264 |
| 21 | regulation of protein deacetylation (GO:0090311) | 4.71381066 |
| 22 | intraciliary transport (GO:0042073) | 4.51594653 |
| 23 | sterol biosynthetic process (GO:0016126) | 4.42561024 |
| 24 | protein localization to synapse (GO:0035418) | 4.30157183 |
| 25 | left/right axis specification (GO:0070986) | 4.27130138 |
| 26 | cranial nerve morphogenesis (GO:0021602) | 4.22592420 |
| 27 | sympathetic nervous system development (GO:0048485) | 4.18166228 |
| 28 | hemoglobin metabolic process (GO:0020027) | 4.08067876 |
| 29 | epithelial cilium movement (GO:0003351) | 4.07743698 |
| 30 | spinal cord association neuron differentiation (GO:0021527) | 4.04778012 |
| 31 | positive regulation of sodium ion transmembrane transporter activity (GO:2000651) | 3.99713889 |
| 32 | behavioral response to ethanol (GO:0048149) | 3.98859218 |
| 33 | regulation of timing of cell differentiation (GO:0048505) | 3.98554652 |
| 34 | cellular response to cholesterol (GO:0071397) | 3.95944549 |
| 35 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339) | 3.95275520 |
| 36 | central nervous system neuron development (GO:0021954) | 3.95220118 |
| 37 | mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686) | 3.92983096 |
| 38 | positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902110 | 3.92983096 |
| 39 | layer formation in cerebral cortex (GO:0021819) | 3.86690709 |
| 40 | positive regulation of oligodendrocyte differentiation (GO:0048714) | 3.81827643 |
| 41 | regulation of development, heterochronic (GO:0040034) | 3.80076682 |
| 42 | homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156) | 3.79829593 |
| 43 | negative regulation of calcium ion-dependent exocytosis (GO:0045955) | 3.74038669 |
| 44 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 3.73482899 |
| 45 | gastrulation with mouth forming second (GO:0001702) | 3.66892499 |
| 46 | maturation of 5.8S rRNA (GO:0000460) | 3.66700263 |
| 47 | short-term memory (GO:0007614) | 3.63092552 |
| 48 | regulation of penile erection (GO:0060405) | 3.55443857 |
| 49 | neural tube formation (GO:0001841) | 3.54235109 |
| 50 | negative regulation of signal transduction by p53 class mediator (GO:1901797) | 3.53958646 |
| 51 | regulation of somitogenesis (GO:0014807) | 3.53332381 |
| 52 | positive regulation of sodium ion transmembrane transport (GO:1902307) | 3.51054255 |
| 53 | interkinetic nuclear migration (GO:0022027) | 3.50476864 |
| 54 | ADP metabolic process (GO:0046031) | 3.46564579 |
| 55 | molting cycle (GO:0042303) | 3.45219070 |
| 56 | hair cycle (GO:0042633) | 3.45219070 |
| 57 | cell differentiation in spinal cord (GO:0021515) | 3.44206740 |
| 58 | interferon-gamma production (GO:0032609) | 3.36626168 |
| 59 | response to misfolded protein (GO:0051788) | 3.34390288 |
| 60 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.33143880 |
| 61 | positive regulation of cellular amide metabolic process (GO:0034250) | 3.31767316 |
| 62 | cardiac right ventricle morphogenesis (GO:0003215) | 3.31048714 |
| 63 | alkaloid metabolic process (GO:0009820) | 3.30770787 |
| 64 | regulation of action potential (GO:0098900) | 3.29514329 |
| 65 | isoprenoid biosynthetic process (GO:0008299) | 3.28580892 |
| 66 | nonmotile primary cilium assembly (GO:0035058) | 3.27622758 |
| 67 | protein localization to microtubule cytoskeleton (GO:0072698) | 3.25033173 |
| 68 | negative regulation of chemotaxis (GO:0050922) | 3.22783931 |
| 69 | cilium movement (GO:0003341) | 3.21801546 |
| 70 | neuron recognition (GO:0008038) | 3.20545957 |
| 71 | cellular response to sterol (GO:0036315) | 3.19820030 |
| 72 | apoptotic process involved in development (GO:1902742) | 3.16098507 |
| 73 | axon regeneration (GO:0031103) | 3.12934734 |
| 74 | cellular response to nitric oxide (GO:0071732) | 3.11108800 |
| 75 | positive regulation of dendritic spine development (GO:0060999) | 3.07066306 |
| 76 | behavioral response to nicotine (GO:0035095) | 3.06595785 |
| 77 | positive regulation of CREB transcription factor activity (GO:0032793) | 3.06043930 |
| 78 | spinal cord motor neuron differentiation (GO:0021522) | 3.05495993 |
| 79 | dendritic spine morphogenesis (GO:0060997) | 3.04098542 |
| 80 | forebrain neuron differentiation (GO:0021879) | 3.02815458 |
| 81 | circadian sleep/wake cycle process (GO:0022410) | 3.00530327 |
| 82 | platelet dense granule organization (GO:0060155) | 2.99101784 |
| 83 | cell-cell adhesion via plasma-membrane adhesion molecules (GO:0098742) | 2.93113352 |
| 84 | cell-cell adhesion (GO:0098609) | 2.91238430 |
| 85 | ubiquinone metabolic process (GO:0006743) | 2.90766979 |
| 86 | regulation of telomere maintenance (GO:0032204) | 2.86553044 |
| 87 | left/right pattern formation (GO:0060972) | 2.84331706 |
| 88 | behavioral response to cocaine (GO:0048148) | 2.84106157 |
| 89 | regulation of synapse assembly (GO:0051963) | 2.82803631 |
| 90 | cerebral cortex neuron differentiation (GO:0021895) | 2.81589940 |
| 91 | regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043516) | 2.80270180 |
| 92 | axoneme assembly (GO:0035082) | 2.79469554 |
| 93 | substrate-independent telencephalic tangential migration (GO:0021826) | 2.76474608 |
| 94 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 2.76474608 |
| 95 | protein localization to cytoskeleton (GO:0044380) | 2.75950584 |
| 96 | mitochondrial fission (GO:0000266) | 2.72008602 |
| 97 | positive regulation of mitochondrial fission (GO:0090141) | 2.71780958 |
| 98 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 2.67628830 |
| 99 | developmental pigmentation (GO:0048066) | 2.67562729 |
| 100 | regulation of beta-amyloid formation (GO:1902003) | 2.67329426 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 6.87979153 |
| 2 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 5.16452123 |
| 3 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 3.81463208 |
| 4 | VDR_22108803_ChIP-Seq_LS180_Human | 3.38844938 |
| 5 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.30096741 |
| 6 | FUS_26573619_Chip-Seq_HEK293_Human | 2.98580316 |
| 7 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.71110836 |
| 8 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.61264799 |
| 9 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.53434122 |
| 10 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.50948699 |
| 11 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.43325795 |
| 12 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.30589560 |
| 13 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.26257022 |
| 14 | AR_21572438_ChIP-Seq_LNCaP_Human | 2.16498352 |
| 15 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 2.11847504 |
| 16 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.03321111 |
| 17 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.99771789 |
| 18 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.93225111 |
| 19 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.89129045 |
| 20 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.89129045 |
| 21 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.88075811 |
| 22 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.85545468 |
| 23 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.80435832 |
| 24 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.79407094 |
| 25 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.74546050 |
| 26 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.72222050 |
| 27 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.67058118 |
| 28 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.63784391 |
| 29 | P300_19829295_ChIP-Seq_ESCs_Human | 1.59878143 |
| 30 | EWS_26573619_Chip-Seq_HEK293_Human | 1.58517625 |
| 31 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.58225431 |
| 32 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.57959600 |
| 33 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.57391861 |
| 34 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.57280728 |
| 35 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.56049017 |
| 36 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.56049017 |
| 37 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.55717133 |
| 38 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.53428681 |
| 39 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.52318573 |
| 40 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.50486412 |
| 41 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.50339941 |
| 42 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.48079246 |
| 43 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.41734779 |
| 44 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.41402095 |
| 45 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.41295129 |
| 46 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.40941736 |
| 47 | STAT3_23295773_ChIP-Seq_U87_Human | 1.40395846 |
| 48 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.39926144 |
| 49 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.34641141 |
| 50 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.33995729 |
| 51 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.33767534 |
| 52 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.33634146 |
| 53 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.32305974 |
| 54 | TCF4_23295773_ChIP-Seq_U87_Human | 1.31960771 |
| 55 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.31819871 |
| 56 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.27952312 |
| 57 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.27619978 |
| 58 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.25943859 |
| 59 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.23642211 |
| 60 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.21283384 |
| 61 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.19545221 |
| 62 | KDM2B_26808549_Chip-Seq_REH_Human | 1.17786616 |
| 63 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 1.17230756 |
| 64 | AR_25329375_ChIP-Seq_VCAP_Human | 1.16874550 |
| 65 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.15224619 |
| 66 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.14856508 |
| 67 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.14040680 |
| 68 | JUN_21703547_ChIP-Seq_K562_Human | 1.10653643 |
| 69 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.10334288 |
| 70 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.09830929 |
| 71 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.07424936 |
| 72 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.07134465 |
| 73 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.07009662 |
| 74 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.05222478 |
| 75 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.04515326 |
| 76 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.04419499 |
| 77 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.03642096 |
| 78 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.03489061 |
| 79 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.02200536 |
| 80 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.02086416 |
| 81 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.02086416 |
| 82 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.01593138 |
| 83 | NCOR_22424771_ChIP-Seq_293T_Human | 1.00992783 |
| 84 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.00682382 |
| 85 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 0.99874657 |
| 86 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.99773914 |
| 87 | TBX3_20139965_ChIP-Seq_ESCs_Mouse | 0.99183917 |
| 88 | TBX3_20139965_ChIP-Seq_MESCs_Mouse | 0.98921672 |
| 89 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.97219552 |
| 90 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.96247225 |
| 91 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.96148270 |
| 92 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.95651803 |
| 93 | REST_21632747_ChIP-Seq_MESCs_Mouse | 0.95617932 |
| 94 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.95223927 |
| 95 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.90580611 |
| 96 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.89694478 |
| 97 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.89414206 |
| 98 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.89359090 |
| 99 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.88440496 |
| 100 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.88418479 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005367_renal/urinary_system_phenotyp | 5.19596155 |
| 2 | MP0000516_abnormal_urinary_system | 5.19596155 |
| 3 | MP0005171_absent_coat_pigmentation | 4.73963013 |
| 4 | MP0005670_abnormal_white_adipose | 4.11889315 |
| 5 | MP0003880_abnormal_central_pattern | 3.77862730 |
| 6 | MP0004133_heterotaxia | 3.43187332 |
| 7 | MP0000372_irregular_coat_pigmentation | 3.28651823 |
| 8 | MP0003890_abnormal_embryonic-extraembry | 3.01240443 |
| 9 | MP0003183_abnormal_peptide_metabolism | 2.98151569 |
| 10 | MP0002938_white_spotting | 2.90577932 |
| 11 | MP0008961_abnormal_basal_metabolism | 2.77025201 |
| 12 | MP0003195_calcinosis | 2.50033200 |
| 13 | MP0000569_abnormal_digit_pigmentation | 2.48181385 |
| 14 | MP0010368_abnormal_lymphatic_system | 2.28015913 |
| 15 | MP0002736_abnormal_nociception_after | 2.26614937 |
| 16 | MP0003221_abnormal_cardiomyocyte_apopto | 2.22249533 |
| 17 | MP0001501_abnormal_sleep_pattern | 1.96697026 |
| 18 | MP0006072_abnormal_retinal_apoptosis | 1.92961391 |
| 19 | MP0001486_abnormal_startle_reflex | 1.77905913 |
| 20 | MP0001485_abnormal_pinna_reflex | 1.73472093 |
| 21 | MP0006276_abnormal_autonomic_nervous | 1.68535983 |
| 22 | MP0002095_abnormal_skin_pigmentation | 1.66197792 |
| 23 | MP0004859_abnormal_synaptic_plasticity | 1.65213845 |
| 24 | MP0004043_abnormal_pH_regulation | 1.60987565 |
| 25 | MP0004215_abnormal_myocardial_fiber | 1.59891337 |
| 26 | MP0002735_abnormal_chemical_nociception | 1.59772167 |
| 27 | MP0002751_abnormal_autonomic_nervous | 1.58498236 |
| 28 | MP0001529_abnormal_vocalization | 1.54427392 |
| 29 | MP0000955_abnormal_spinal_cord | 1.51918973 |
| 30 | MP0001968_abnormal_touch/_nociception | 1.48868229 |
| 31 | MP0000534_abnormal_ureter_morphology | 1.47396142 |
| 32 | MP0003136_yellow_coat_color | 1.46918154 |
| 33 | MP0002822_catalepsy | 1.44474869 |
| 34 | MP0002249_abnormal_larynx_morphology | 1.41864330 |
| 35 | MP0002572_abnormal_emotion/affect_behav | 1.41233668 |
| 36 | MP0005253_abnormal_eye_physiology | 1.34749279 |
| 37 | MP0006292_abnormal_olfactory_placode | 1.31550051 |
| 38 | MP0003119_abnormal_digestive_system | 1.27049508 |
| 39 | MP0009046_muscle_twitch | 1.25928693 |
| 40 | MP0005187_abnormal_penis_morphology | 1.22668890 |
| 41 | MP0002234_abnormal_pharynx_morphology | 1.18944485 |
| 42 | MP0000751_myopathy | 1.17697585 |
| 43 | MP0010329_abnormal_lipoprotein_level | 1.17272900 |
| 44 | MP0005085_abnormal_gallbladder_physiolo | 1.16694499 |
| 45 | MP0008569_lethality_at_weaning | 1.09928543 |
| 46 | MP0006138_congestive_heart_failure | 1.08719125 |
| 47 | MP0000681_abnormal_thyroid_gland | 1.08698070 |
| 48 | MP0004885_abnormal_endolymph | 1.06090454 |
| 49 | MP0002063_abnormal_learning/memory/cond | 1.05151878 |
| 50 | MP0002928_abnormal_bile_duct | 1.04994304 |
| 51 | MP0005174_abnormal_tail_pigmentation | 1.01568397 |
| 52 | MP0009745_abnormal_behavioral_response | 0.98726723 |
| 53 | MP0000778_abnormal_nervous_system | 0.96027920 |
| 54 | MP0004742_abnormal_vestibular_system | 0.93655720 |
| 55 | MP0002882_abnormal_neuron_morphology | 0.92435773 |
| 56 | MP0002090_abnormal_vision | 0.91720930 |
| 57 | MP0003122_maternal_imprinting | 0.89963474 |
| 58 | MP0003938_abnormal_ear_development | 0.86589583 |
| 59 | MP0005391_vision/eye_phenotype | 0.85453357 |
| 60 | MP0000631_abnormal_neuroendocrine_gland | 0.85369053 |
| 61 | MP0002067_abnormal_sensory_capabilities | 0.85322182 |
| 62 | MP0002127_abnormal_cardiovascular_syste | 0.84412928 |
| 63 | MP0002752_abnormal_somatic_nervous | 0.84270090 |
| 64 | MP0000026_abnormal_inner_ear | 0.83580420 |
| 65 | MP0002184_abnormal_innervation | 0.83311432 |
| 66 | MP0009697_abnormal_copulation | 0.82813141 |
| 67 | MP0004145_abnormal_muscle_electrophysio | 0.82204935 |
| 68 | MP0000465_gastrointestinal_hemorrhage | 0.82091614 |
| 69 | MP0005377_hearing/vestibular/ear_phenot | 0.80650286 |
| 70 | MP0003878_abnormal_ear_physiology | 0.80650286 |
| 71 | MP0000049_abnormal_middle_ear | 0.80462680 |
| 72 | MP0003635_abnormal_synaptic_transmissio | 0.80271470 |
| 73 | MP0002272_abnormal_nervous_system | 0.79988944 |
| 74 | MP0005248_abnormal_Harderian_gland | 0.77843175 |
| 75 | MP0002152_abnormal_brain_morphology | 0.77622093 |
| 76 | MP0008789_abnormal_olfactory_epithelium | 0.76893139 |
| 77 | MP0004811_abnormal_neuron_physiology | 0.74263994 |
| 78 | MP0005195_abnormal_posterior_eye | 0.73529495 |
| 79 | MP0005551_abnormal_eye_electrophysiolog | 0.73369318 |
| 80 | MP0003121_genomic_imprinting | 0.73240937 |
| 81 | MP0008057_abnormal_DNA_replication | 0.72692159 |
| 82 | MP0002638_abnormal_pupillary_reflex | 0.72332730 |
| 83 | MP0001440_abnormal_grooming_behavior | 0.71404089 |
| 84 | MP0000678_abnormal_parathyroid_gland | 0.70684697 |
| 85 | MP0002557_abnormal_social/conspecific_i | 0.70115918 |
| 86 | MP0002064_seizures | 0.69868494 |
| 87 | MP0009250_abnormal_appendicular_skeleto | 0.69514364 |
| 88 | MP0003137_abnormal_impulse_conducting | 0.67645246 |
| 89 | MP0002092_abnormal_eye_morphology | 0.67376722 |
| 90 | MP0002111_abnormal_tail_morphology | 0.66546038 |
| 91 | MP0002282_abnormal_trachea_morphology | 0.65810822 |
| 92 | MP0004270_analgesia | 0.64646237 |
| 93 | MP0002229_neurodegeneration | 0.64037333 |
| 94 | MP0003861_abnormal_nervous_system | 0.62974257 |
| 95 | MP0002837_dystrophic_cardiac_calcinosis | 0.62797332 |
| 96 | MP0001293_anophthalmia | 0.61987825 |
| 97 | MP0005083_abnormal_biliary_tract | 0.59949425 |
| 98 | MP0004085_abnormal_heartbeat | 0.59758165 |
| 99 | MP0005448_abnormal_energy_balance | 0.59747168 |
| 100 | MP0002066_abnormal_motor_capabilities/c | 0.59312908 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Failure to thrive in infancy (HP:0001531) | 8.13247302 |
| 2 | Febrile seizures (HP:0002373) | 5.48432067 |
| 3 | Split foot (HP:0001839) | 4.70251911 |
| 4 | Congenital sensorineural hearing impairment (HP:0008527) | 3.88769239 |
| 5 | Renal hypoplasia (HP:0000089) | 3.75953821 |
| 6 | Focal motor seizures (HP:0011153) | 3.74501164 |
| 7 | Rib fusion (HP:0000902) | 3.58589784 |
| 8 | Severe global developmental delay (HP:0011344) | 3.26774882 |
| 9 | Broad alveolar ridges (HP:0000187) | 3.11763027 |
| 10 | Abnormal auditory evoked potentials (HP:0006958) | 3.10800957 |
| 11 | Patchy hypopigmentation of hair (HP:0011365) | 3.08740641 |
| 12 | Intestinal atresia (HP:0011100) | 3.08439386 |
| 13 | Congenital, generalized hypertrichosis (HP:0004540) | 3.06537970 |
| 14 | Medial flaring of the eyebrow (HP:0010747) | 3.04961682 |
| 15 | Progressive external ophthalmoplegia (HP:0000590) | 3.02647298 |
| 16 | Methylmalonic acidemia (HP:0002912) | 2.98124801 |
| 17 | Gait imbalance (HP:0002141) | 2.95661471 |
| 18 | Papillary thyroid carcinoma (HP:0002895) | 2.93114412 |
| 19 | Congenital primary aphakia (HP:0007707) | 2.88997043 |
| 20 | External ophthalmoplegia (HP:0000544) | 2.80124122 |
| 21 | Median cleft lip (HP:0000161) | 2.77750199 |
| 22 | Shoulder girdle muscle weakness (HP:0003547) | 2.77301627 |
| 23 | Hyperglycinemia (HP:0002154) | 2.71532508 |
| 24 | Abnormality of the axillary hair (HP:0100134) | 2.67973786 |
| 25 | Abnormality of secondary sexual hair (HP:0009888) | 2.67973786 |
| 26 | Hypoplastic pelvis (HP:0008839) | 2.67628720 |
| 27 | Molar tooth sign on MRI (HP:0002419) | 2.63729932 |
| 28 | Abnormality of midbrain morphology (HP:0002418) | 2.63729932 |
| 29 | Progressive cerebellar ataxia (HP:0002073) | 2.63143436 |
| 30 | Myelomeningocele (HP:0002475) | 2.59219329 |
| 31 | Thyroid carcinoma (HP:0002890) | 2.56041889 |
| 32 | Complete atrioventricular canal defect (HP:0001674) | 2.54536775 |
| 33 | Short humerus (HP:0005792) | 2.50706966 |
| 34 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.49833394 |
| 35 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.49833394 |
| 36 | Methylmalonic aciduria (HP:0012120) | 2.49791247 |
| 37 | Poor coordination (HP:0002370) | 2.49046017 |
| 38 | Parakeratosis (HP:0001036) | 2.47560891 |
| 39 | High anterior hairline (HP:0009890) | 2.46381224 |
| 40 | Pelvic girdle muscle weakness (HP:0003749) | 2.42624148 |
| 41 | White forelock (HP:0002211) | 2.42577880 |
| 42 | Neonatal respiratory distress (HP:0002643) | 2.40936731 |
| 43 | Tubulointerstitial nephritis (HP:0001970) | 2.38537690 |
| 44 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.36591522 |
| 45 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.36282435 |
| 46 | Absent/shortened dynein arms (HP:0200106) | 2.36282435 |
| 47 | Anomalous pulmonary venous return (HP:0010772) | 2.35481720 |
| 48 | Mutism (HP:0002300) | 2.35381578 |
| 49 | Aplasia/hypoplasia of the humerus (HP:0006507) | 2.35242687 |
| 50 | Nephrogenic diabetes insipidus (HP:0009806) | 2.34731966 |
| 51 | Adactyly (HP:0009776) | 2.34616232 |
| 52 | Narrow forehead (HP:0000341) | 2.34466852 |
| 53 | Cortical visual impairment (HP:0100704) | 2.34041790 |
| 54 | Amyotrophic lateral sclerosis (HP:0007354) | 2.32405652 |
| 55 | Cutaneous finger syndactyly (HP:0010554) | 2.30167481 |
| 56 | Meningocele (HP:0002435) | 2.28473899 |
| 57 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.25266593 |
| 58 | Short 4th metacarpal (HP:0010044) | 2.25266593 |
| 59 | Abnormality of placental membranes (HP:0011409) | 2.23238224 |
| 60 | Amniotic constriction ring (HP:0009775) | 2.23238224 |
| 61 | Abnormality of the renal medulla (HP:0100957) | 2.17716710 |
| 62 | Abnormality of the shoulder girdle musculature (HP:0001435) | 2.17580951 |
| 63 | Abnormality of the hip-girdle musculature (HP:0001445) | 2.17107036 |
| 64 | Abnormality of the musculature of the pelvis (HP:0001469) | 2.17107036 |
| 65 | Hyperkalemia (HP:0002153) | 2.15105391 |
| 66 | Epidermoid cyst (HP:0200040) | 2.14583153 |
| 67 | Supernumerary spleens (HP:0009799) | 2.13751222 |
| 68 | Postaxial hand polydactyly (HP:0001162) | 2.12823064 |
| 69 | Long foot (HP:0001833) | 2.07167811 |
| 70 | True hermaphroditism (HP:0010459) | 2.05276398 |
| 71 | Abnormality of abdominal situs (HP:0011620) | 2.03047488 |
| 72 | Abdominal situs inversus (HP:0003363) | 2.03047488 |
| 73 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 2.01998870 |
| 74 | Abnormality of the pulmonary veins (HP:0011718) | 2.00600158 |
| 75 | Heterochromia iridis (HP:0001100) | 1.99957396 |
| 76 | Vaginal atresia (HP:0000148) | 1.99246496 |
| 77 | Atrioventricular canal defect (HP:0006695) | 1.97768661 |
| 78 | Hypokalemic alkalosis (HP:0001949) | 1.96841209 |
| 79 | Colon cancer (HP:0003003) | 1.94648203 |
| 80 | Abnormal ciliary motility (HP:0012262) | 1.91836312 |
| 81 | Genital tract atresia (HP:0001827) | 1.90988495 |
| 82 | Gastrointestinal atresia (HP:0002589) | 1.89883673 |
| 83 | Blue irides (HP:0000635) | 1.88852428 |
| 84 | Confusion (HP:0001289) | 1.87407393 |
| 85 | Tented upper lip vermilion (HP:0010804) | 1.86641459 |
| 86 | Proximal placement of thumb (HP:0009623) | 1.86329798 |
| 87 | Cutaneous syndactyly (HP:0012725) | 1.85993535 |
| 88 | Oligodactyly (HP:0012165) | 1.83182052 |
| 89 | Pancreatic cysts (HP:0001737) | 1.82758686 |
| 90 | Synostosis of carpal bones (HP:0005048) | 1.81060489 |
| 91 | Synostosis involving the elbow (HP:0003938) | 1.79462994 |
| 92 | Humeroradial synostosis (HP:0003041) | 1.79462994 |
| 93 | Specific learning disability (HP:0001328) | 1.79156563 |
| 94 | Pancreatic fibrosis (HP:0100732) | 1.78975001 |
| 95 | Hemivertebrae (HP:0002937) | 1.77413495 |
| 96 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.77230136 |
| 97 | Large for gestational age (HP:0001520) | 1.76081130 |
| 98 | Hallux valgus (HP:0001822) | 1.75780034 |
| 99 | Smooth philtrum (HP:0000319) | 1.75206596 |
| 100 | Abnormality of homocysteine metabolism (HP:0010919) | 1.74462284 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TAF1 | 5.96233583 |
| 2 | FGFR3 | 5.44715638 |
| 3 | MAP3K4 | 5.01852822 |
| 4 | MAP2K7 | 4.89413127 |
| 5 | WNK3 | 3.75430399 |
| 6 | DYRK1A | 3.13610192 |
| 7 | MAP3K6 | 3.10345252 |
| 8 | MAP2K4 | 2.85032791 |
| 9 | EPHB1 | 2.70463589 |
| 10 | BCR | 2.64430773 |
| 11 | EPHA3 | 2.11529516 |
| 12 | MAPK13 | 2.00404057 |
| 13 | MARK1 | 1.97506474 |
| 14 | MKNK2 | 1.78093068 |
| 15 | MAP4K2 | 1.73670862 |
| 16 | MKNK1 | 1.51926644 |
| 17 | PASK | 1.40548051 |
| 18 | FRK | 1.40015905 |
| 19 | SRPK1 | 1.38583095 |
| 20 | PAK6 | 1.36356308 |
| 21 | ADRBK2 | 1.34806917 |
| 22 | CAMKK2 | 1.33543395 |
| 23 | CAMKK1 | 1.31779731 |
| 24 | WNK4 | 1.24469400 |
| 25 | CSNK1G3 | 1.21883789 |
| 26 | CSNK1A1L | 1.18232977 |
| 27 | DYRK1B | 1.10134331 |
| 28 | CSNK1G2 | 1.05049839 |
| 29 | DAPK2 | 1.04874398 |
| 30 | MAP3K5 | 1.03924573 |
| 31 | PNCK | 0.98399481 |
| 32 | TRIM28 | 0.94358290 |
| 33 | CDK3 | 0.92706731 |
| 34 | CSNK1G1 | 0.91875168 |
| 35 | DYRK3 | 0.88302610 |
| 36 | ERBB3 | 0.86460156 |
| 37 | CASK | 0.85992380 |
| 38 | BRSK2 | 0.74833268 |
| 39 | INSRR | 0.73223930 |
| 40 | MATK | 0.72812423 |
| 41 | EPHA4 | 0.69300234 |
| 42 | UHMK1 | 0.69087071 |
| 43 | ERBB2 | 0.67979842 |
| 44 | STK39 | 0.67209505 |
| 45 | BCKDK | 0.66520383 |
| 46 | PRKCG | 0.65662430 |
| 47 | NUAK1 | 0.62949435 |
| 48 | NTRK1 | 0.62363065 |
| 49 | PKN1 | 0.61881158 |
| 50 | DYRK2 | 0.58618119 |
| 51 | OXSR1 | 0.55003954 |
| 52 | PINK1 | 0.54187182 |
| 53 | ADRBK1 | 0.50942814 |
| 54 | ATR | 0.49963657 |
| 55 | PAK3 | 0.49912390 |
| 56 | CDK8 | 0.48421960 |
| 57 | TESK1 | 0.48357166 |
| 58 | MAPK15 | 0.47577633 |
| 59 | PRKD3 | 0.46911473 |
| 60 | CAMK2A | 0.46305461 |
| 61 | CAMK4 | 0.45574403 |
| 62 | CLK1 | 0.44339984 |
| 63 | WNK1 | 0.43972959 |
| 64 | SGK1 | 0.42192096 |
| 65 | CAMK2B | 0.41388305 |
| 66 | NEK1 | 0.40895595 |
| 67 | TAOK3 | 0.40721389 |
| 68 | CSNK1E | 0.36887666 |
| 69 | VRK2 | 0.35558394 |
| 70 | PRKACB | 0.35244808 |
| 71 | GRK1 | 0.34837472 |
| 72 | IRAK4 | 0.34320711 |
| 73 | PLK2 | 0.34130256 |
| 74 | INSR | 0.34087001 |
| 75 | BRSK1 | 0.31834771 |
| 76 | MOS | 0.31706881 |
| 77 | NTRK2 | 0.31557379 |
| 78 | PRKACA | 0.31274286 |
| 79 | VRK1 | 0.31108299 |
| 80 | MAP2K6 | 0.29672831 |
| 81 | CHUK | 0.28351632 |
| 82 | LIMK1 | 0.28183904 |
| 83 | PRKAA2 | 0.27829804 |
| 84 | RPS6KA4 | 0.27795914 |
| 85 | PRKCE | 0.27700117 |
| 86 | CDK19 | 0.26125501 |
| 87 | PIK3CA | 0.24082180 |
| 88 | CDK14 | 0.23628514 |
| 89 | IRAK2 | 0.23144561 |
| 90 | BMPR1B | 0.22690964 |
| 91 | CAMK2D | 0.22468946 |
| 92 | OBSCN | 0.20675028 |
| 93 | CSNK1A1 | 0.20382646 |
| 94 | IRAK1 | 0.19979236 |
| 95 | PRKCB | 0.19797365 |
| 96 | CAMK1 | 0.17915159 |
| 97 | PRKCZ | 0.14969352 |
| 98 | NME1 | 0.14205998 |
| 99 | TRPM7 | 0.13736913 |
| 100 | PRKACG | 0.13559807 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 7.86984965 |
| 2 | Steroid biosynthesis_Homo sapiens_hsa00100 | 4.95355757 |
| 3 | Propanoate metabolism_Homo sapiens_hsa00640 | 4.17590649 |
| 4 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 3.42106476 |
| 5 | Pyruvate metabolism_Homo sapiens_hsa00620 | 3.35291863 |
| 6 | Butanoate metabolism_Homo sapiens_hsa00650 | 3.29248071 |
| 7 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 3.09635954 |
| 8 | Taste transduction_Homo sapiens_hsa04742 | 2.90869869 |
| 9 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.02235540 |
| 10 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.78044026 |
| 11 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.76286534 |
| 12 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.68898156 |
| 13 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.58789408 |
| 14 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.57440475 |
| 15 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.50334533 |
| 16 | Basal transcription factors_Homo sapiens_hsa03022 | 1.47401409 |
| 17 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.32058514 |
| 18 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.30631311 |
| 19 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.27211178 |
| 20 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.25272259 |
| 21 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.24941762 |
| 22 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.23211011 |
| 23 | Circadian rhythm_Homo sapiens_hsa04710 | 1.20009359 |
| 24 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.17505168 |
| 25 | Nicotine addiction_Homo sapiens_hsa05033 | 1.11907102 |
| 26 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.11343678 |
| 27 | Axon guidance_Homo sapiens_hsa04360 | 1.09058644 |
| 28 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.06668443 |
| 29 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.94764549 |
| 30 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.92954262 |
| 31 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.89988310 |
| 32 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.88525642 |
| 33 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.87748118 |
| 34 | Spliceosome_Homo sapiens_hsa03040 | 0.86330797 |
| 35 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.84118394 |
| 36 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.80234662 |
| 37 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.74597035 |
| 38 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.74518188 |
| 39 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.74190876 |
| 40 | Olfactory transduction_Homo sapiens_hsa04740 | 0.74079446 |
| 41 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.73045127 |
| 42 | Protein export_Homo sapiens_hsa03060 | 0.71176186 |
| 43 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.70397678 |
| 44 | Peroxisome_Homo sapiens_hsa04146 | 0.70174089 |
| 45 | Retinol metabolism_Homo sapiens_hsa00830 | 0.70122509 |
| 46 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.70017202 |
| 47 | Morphine addiction_Homo sapiens_hsa05032 | 0.69971203 |
| 48 | Long-term depression_Homo sapiens_hsa04730 | 0.65802022 |
| 49 | Circadian entrainment_Homo sapiens_hsa04713 | 0.63023599 |
| 50 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.62357721 |
| 51 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.59315814 |
| 52 | Metabolic pathways_Homo sapiens_hsa01100 | 0.58697373 |
| 53 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.53658303 |
| 54 | GABAergic synapse_Homo sapiens_hsa04727 | 0.51978258 |
| 55 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.50672121 |
| 56 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.49953082 |
| 57 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.49785274 |
| 58 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.46960632 |
| 59 | Phototransduction_Homo sapiens_hsa04744 | 0.45824031 |
| 60 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.45301163 |
| 61 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.44439490 |
| 62 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.43648754 |
| 63 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.43201940 |
| 64 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.42635165 |
| 65 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.41614020 |
| 66 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.41319076 |
| 67 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.40543272 |
| 68 | Huntingtons disease_Homo sapiens_hsa05016 | 0.39039439 |
| 69 | Parkinsons disease_Homo sapiens_hsa05012 | 0.37461008 |
| 70 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.36326369 |
| 71 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.35498522 |
| 72 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.35275286 |
| 73 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.33719918 |
| 74 | ABC transporters_Homo sapiens_hsa02010 | 0.33388352 |
| 75 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.32126773 |
| 76 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.30779334 |
| 77 | Cocaine addiction_Homo sapiens_hsa05030 | 0.30406433 |
| 78 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.29910627 |
| 79 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.29000282 |
| 80 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.26668687 |
| 81 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.25041741 |
| 82 | RNA degradation_Homo sapiens_hsa03018 | 0.24789095 |
| 83 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.24239560 |
| 84 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.22712335 |
| 85 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.21124661 |
| 86 | Salivary secretion_Homo sapiens_hsa04970 | 0.21082183 |
| 87 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.20840669 |
| 88 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.20141102 |
| 89 | Purine metabolism_Homo sapiens_hsa00230 | 0.20110362 |
| 90 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.19505591 |
| 91 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.18777144 |
| 92 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.18636116 |
| 93 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.18087261 |
| 94 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.16764685 |
| 95 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.16344000 |
| 96 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.15676009 |
| 97 | Alcoholism_Homo sapiens_hsa05034 | 0.14857974 |
| 98 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.14320731 |
| 99 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.13488078 |
| 100 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.13327968 |

