Rank | Gene Set | Z-score |
---|---|---|
1 | protein localization to kinetochore (GO:0034501) | 6.02706013 |
2 | nuclear pore organization (GO:0006999) | 5.39025462 |
3 | nuclear pore complex assembly (GO:0051292) | 5.36693165 |
4 | DNA replication-dependent nucleosome organization (GO:0034723) | 5.18287385 |
5 | DNA replication-dependent nucleosome assembly (GO:0006335) | 5.18287385 |
6 | protein localization to chromosome, centromeric region (GO:0071459) | 4.98718237 |
7 | DNA replication checkpoint (GO:0000076) | 4.94334165 |
8 | meiotic chromosome segregation (GO:0045132) | 4.90394254 |
9 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 4.89591335 |
10 | mitotic sister chromatid segregation (GO:0000070) | 4.89153441 |
11 | daunorubicin metabolic process (GO:0044597) | 4.73071559 |
12 | polyketide metabolic process (GO:0030638) | 4.73071559 |
13 | doxorubicin metabolic process (GO:0044598) | 4.73071559 |
14 | DNA unwinding involved in DNA replication (GO:0006268) | 4.61817332 |
15 | sister chromatid segregation (GO:0000819) | 4.46179851 |
16 | negative regulation of G2/M transition of mitotic cell cycle (GO:0010972) | 4.24307460 |
17 | regulation of telomere maintenance via telomerase (GO:0032210) | 4.18938901 |
18 | regulation of centriole replication (GO:0046599) | 4.09751498 |
19 | mitotic chromosome condensation (GO:0007076) | 4.09197978 |
20 | * DNA replication initiation (GO:0006270) | 4.08586248 |
21 | ribosome biogenesis (GO:0042254) | 4.03065383 |
22 | pore complex assembly (GO:0046931) | 4.02493759 |
23 | mitotic metaphase plate congression (GO:0007080) | 3.99722635 |
24 | mitotic nuclear envelope disassembly (GO:0007077) | 3.97877803 |
25 | formation of translation preinitiation complex (GO:0001731) | 3.95562812 |
26 | negative regulation of cell cycle G2/M phase transition (GO:1902750) | 3.94729423 |
27 | mitotic sister chromatid cohesion (GO:0007064) | 3.92386756 |
28 | rRNA modification (GO:0000154) | 3.88124135 |
29 | heterochromatin organization (GO:0070828) | 3.87334330 |
30 | DNA duplex unwinding (GO:0032508) | 3.83810506 |
31 | DNA geometric change (GO:0032392) | 3.83112185 |
32 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.80300931 |
33 | histone H4-K12 acetylation (GO:0043983) | 3.79649336 |
34 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.77884582 |
35 | non-recombinational repair (GO:0000726) | 3.77884582 |
36 | rRNA methylation (GO:0031167) | 3.77487667 |
37 | chromatin assembly (GO:0031497) | 3.74600435 |
38 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.74024176 |
39 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.73464028 |
40 | nuclear envelope disassembly (GO:0051081) | 3.70133712 |
41 | membrane disassembly (GO:0030397) | 3.70133712 |
42 | regulation of translation in response to stress (GO:0043555) | 3.64775349 |
43 | regulation of centrosome cycle (GO:0046605) | 3.64353181 |
44 | rRNA transcription (GO:0009303) | 3.63457197 |
45 | negative regulation of telomerase activity (GO:0051974) | 3.61618959 |
46 | DNA strand elongation (GO:0022616) | 3.59726369 |
47 | histone H4-K5 acetylation (GO:0043981) | 3.57765372 |
48 | histone H4-K8 acetylation (GO:0043982) | 3.57765372 |
49 | reciprocal DNA recombination (GO:0035825) | 3.57047477 |
50 | reciprocal meiotic recombination (GO:0007131) | 3.57047477 |
51 | regulation of centrosome duplication (GO:0010824) | 3.56310581 |
52 | chromatin remodeling at centromere (GO:0031055) | 3.53835424 |
53 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.52964562 |
54 | replication fork processing (GO:0031297) | 3.49734332 |
55 | CENP-A containing nucleosome assembly (GO:0034080) | 3.49442126 |
56 | metaphase plate congression (GO:0051310) | 3.48011728 |
57 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.46229934 |
58 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.45877780 |
59 | IMP biosynthetic process (GO:0006188) | 3.44971002 |
60 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.42304540 |
61 | DNA replication-independent nucleosome organization (GO:0034724) | 3.42304540 |
62 | positive regulation of DNA-dependent DNA replication (GO:2000105) | 3.41721482 |
63 | ncRNA catabolic process (GO:0034661) | 3.41230317 |
64 | chromatin assembly or disassembly (GO:0006333) | 3.40700654 |
65 | pre-miRNA processing (GO:0031054) | 3.40048416 |
66 | nucleobase biosynthetic process (GO:0046112) | 3.38333716 |
67 | mitochondrial RNA metabolic process (GO:0000959) | 3.37074711 |
68 | DNA double-strand break processing (GO:0000729) | 3.36686039 |
69 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 3.36206258 |
70 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.34812576 |
71 | negative regulation of epidermis development (GO:0045683) | 3.34405826 |
72 | regulation of gene silencing by RNA (GO:0060966) | 3.33329183 |
73 | regulation of posttranscriptional gene silencing (GO:0060147) | 3.33329183 |
74 | regulation of gene silencing by miRNA (GO:0060964) | 3.33329183 |
75 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.31117911 |
76 | protein K11-linked deubiquitination (GO:0035871) | 3.28436427 |
77 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.27729832 |
78 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.27729832 |
79 | ribosome assembly (GO:0042255) | 3.27275893 |
80 | protein localization to chromosome (GO:0034502) | 3.22712438 |
81 | mitotic recombination (GO:0006312) | 3.21103544 |
82 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 3.20562745 |
83 | double-strand break repair via homologous recombination (GO:0000724) | 3.20548073 |
84 | purine nucleobase biosynthetic process (GO:0009113) | 3.19401041 |
85 | rRNA catabolic process (GO:0016075) | 3.19222534 |
86 | recombinational repair (GO:0000725) | 3.18718010 |
87 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 3.18396127 |
88 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 3.18396127 |
89 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 3.18396127 |
90 | maintenance of protein location in nucleus (GO:0051457) | 3.17965676 |
91 | cullin deneddylation (GO:0010388) | 3.17945989 |
92 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.17593004 |
93 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.17593004 |
94 | regulation of double-strand break repair (GO:2000779) | 3.17025192 |
95 | DNA conformation change (GO:0071103) | 3.16055404 |
96 | protein K6-linked ubiquitination (GO:0085020) | 3.15261202 |
97 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.14315735 |
98 | pseudouridine synthesis (GO:0001522) | 3.14202591 |
99 | regulation of helicase activity (GO:0051095) | 3.13645823 |
100 | monoubiquitinated protein deubiquitination (GO:0035520) | 3.13556534 |
101 | positive regulation of histone H3-K4 methylation (GO:0051571) | 3.10708171 |
102 | kinetochore organization (GO:0051383) | 3.10046132 |
103 | spindle assembly checkpoint (GO:0071173) | 3.08843565 |
104 | spindle checkpoint (GO:0031577) | 3.08531394 |
105 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 3.08280360 |
106 | telomere maintenance via recombination (GO:0000722) | 3.08069929 |
107 | UDP-N-acetylglucosamine metabolic process (GO:0006047) | 3.06737445 |
108 | peptidyl-threonine dephosphorylation (GO:0035970) | 3.06467646 |
109 | IMP metabolic process (GO:0046040) | 3.06152553 |
110 | histone exchange (GO:0043486) | 3.05573501 |
111 | establishment of chromosome localization (GO:0051303) | 3.03883411 |
112 | negative regulation of telomere maintenance (GO:0032205) | 3.03626283 |
113 | negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147) | 3.01873898 |
114 | sister chromatid cohesion (GO:0007062) | 3.01399954 |
115 | regulation of DNA endoreduplication (GO:0032875) | 3.01224833 |
116 | positive regulation of chromosome segregation (GO:0051984) | 3.00263096 |
117 | regulation of chromosome segregation (GO:0051983) | 3.00121272 |
118 | establishment of integrated proviral latency (GO:0075713) | 2.99676532 |
119 | regulation of DNA-dependent DNA replication (GO:0090329) | 2.99127462 |
120 | regulation of spindle organization (GO:0090224) | 2.97866079 |
121 | histone-serine phosphorylation (GO:0035404) | 2.97282784 |
122 | negative regulation of chromosome segregation (GO:0051985) | 2.96905466 |
123 | synapsis (GO:0007129) | 2.94176632 |
124 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 2.93703707 |
125 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 2.93703707 |
126 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 2.93703707 |
127 | negative regulation of sister chromatid segregation (GO:0033046) | 2.93703707 |
128 | chromosome segregation (GO:0007059) | 2.93122365 |
129 | aminoglycoside antibiotic metabolic process (GO:0030647) | 2.91194800 |
130 | mismatch repair (GO:0006298) | 2.91173702 |
131 | protein deneddylation (GO:0000338) | 2.90089915 |
132 | RNA stabilization (GO:0043489) | 2.89866593 |
133 | mRNA stabilization (GO:0048255) | 2.89866593 |
134 | mitotic G2/M transition checkpoint (GO:0044818) | 2.89417076 |
135 | DNA ligation (GO:0006266) | 2.89095542 |
136 | chromosome condensation (GO:0030261) | 2.87300903 |
137 | double-strand break repair (GO:0006302) | 2.83591171 |
138 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.83051310 |
139 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.83051310 |
140 | isotype switching (GO:0045190) | 2.83051310 |
141 | mitotic spindle checkpoint (GO:0071174) | 2.82031843 |
142 | regulation of histone H3-K9 methylation (GO:0051570) | 2.81812216 |
143 | response to X-ray (GO:0010165) | 2.78867381 |
144 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 2.77958469 |
145 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 2.77958469 |
146 | regulation of mitotic sister chromatid separation (GO:0010965) | 2.75951158 |
147 | regulation of mitotic sister chromatid segregation (GO:0033047) | 2.75951158 |
148 | regulation of sister chromatid segregation (GO:0033045) | 2.75951158 |
149 | negative regulation of DNA repair (GO:0045738) | 2.75682591 |
150 | DNA strand renaturation (GO:0000733) | 2.74027916 |
151 | DNA recombination (GO:0006310) | 2.73820913 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 9.19725041 |
2 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 4.20254104 |
3 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 4.14777152 |
4 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.85593668 |
5 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 3.35895062 |
6 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 3.35895062 |
7 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 3.35895062 |
8 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.19887690 |
9 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.88523279 |
10 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.83534652 |
11 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.80849893 |
12 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.69175502 |
13 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.57527051 |
14 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.39063001 |
15 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.35023899 |
16 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 2.32802866 |
17 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.32214394 |
18 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.29071042 |
19 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.28182449 |
20 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.25625943 |
21 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.24766449 |
22 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 2.24003459 |
23 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.22581771 |
24 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 2.15006284 |
25 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.14973520 |
26 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 2.10404392 |
27 | EWS_26573619_Chip-Seq_HEK293_Human | 2.09993960 |
28 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.03795254 |
29 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.03044757 |
30 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.02475504 |
31 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.99655838 |
32 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.98502089 |
33 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.96997339 |
34 | FUS_26573619_Chip-Seq_HEK293_Human | 1.94715647 |
35 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.92705269 |
36 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.91515724 |
37 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.89172965 |
38 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.87945664 |
39 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.86566733 |
40 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.82336981 |
41 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.81430041 |
42 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.77095272 |
43 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.75568958 |
44 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.73354120 |
45 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.69583471 |
46 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.69281449 |
47 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.68763691 |
48 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.67732302 |
49 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.67001569 |
50 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.64879255 |
51 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 1.64848062 |
52 | VDR_22108803_ChIP-Seq_LS180_Human | 1.64256642 |
53 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.62161696 |
54 | TCF3_18692474_ChIP-Seq_MESCs_Mouse | 1.58311442 |
55 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.57839188 |
56 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.57026286 |
57 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.56144814 |
58 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.52741351 |
59 | MYC_22102868_ChIP-Seq_BL_Human | 1.51536416 |
60 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.50625585 |
61 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.48658154 |
62 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.47058132 |
63 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.45160598 |
64 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.44553238 |
65 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.40637343 |
66 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.40302604 |
67 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.39121461 |
68 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.38494654 |
69 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.37261276 |
70 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.37086993 |
71 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 1.36190209 |
72 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.35431796 |
73 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.34371743 |
74 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.33528277 |
75 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.31906141 |
76 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.29320084 |
77 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.26706865 |
78 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.26574632 |
79 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.24540492 |
80 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.23325491 |
81 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.20257847 |
82 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.20175366 |
83 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.20089906 |
84 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.19783339 |
85 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.19696635 |
86 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.18900574 |
87 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.18779918 |
88 | P300_19829295_ChIP-Seq_ESCs_Human | 1.17966009 |
89 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.16870494 |
90 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.16721704 |
91 | NANOG_18347094_ChIP-ChIP_MESCs_Mouse | 1.14549016 |
92 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.13221948 |
93 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.12399450 |
94 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.12170848 |
95 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.11566140 |
96 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.10939969 |
97 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 1.10461554 |
98 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.10352182 |
99 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.10144734 |
100 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.08110501 |
101 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.07383119 |
102 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.06730661 |
103 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.06643679 |
104 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.06217724 |
105 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.02426667 |
106 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.02133184 |
107 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.01180733 |
108 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.00557842 |
109 | POU5F1_18692474_ChIP-Seq_MESCs_Mouse | 0.99885224 |
110 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.99765036 |
111 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.99427704 |
112 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.98643793 |
113 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.98389150 |
114 | SOX2_18692474_ChIP-Seq_MESCs_Mouse | 0.97485856 |
115 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.97162929 |
116 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.97067481 |
117 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 0.96968592 |
118 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.96214303 |
119 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.96100539 |
120 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.95618107 |
121 | TCF4_23295773_ChIP-Seq_U87_Human | 0.95560957 |
122 | NANOG_18692474_ChIP-Seq_MEFs_Mouse | 0.95171250 |
123 | POU5F1_16518401_ChIP-PET_MESCs_Mouse | 0.94269139 |
124 | STAT3_23295773_ChIP-Seq_U87_Human | 0.94113346 |
125 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.92674202 |
126 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.92629239 |
127 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.92568115 |
128 | FOXA1_26743006_Chip-Seq_LNCaP-abl_Human | 0.92394190 |
129 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.92304036 |
130 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.92252294 |
131 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.92174236 |
132 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.91934003 |
133 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.91934003 |
134 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.91694425 |
135 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.91400325 |
136 | TCF3_18347094_ChIP-ChIP_MESCs_Mouse | 0.90726071 |
137 | NANOG_18692474_ChIP-Seq_MESCs_Mouse | 0.90667013 |
138 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.90530979 |
139 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.89925506 |
140 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 0.89897783 |
141 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.89260488 |
142 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.89026480 |
143 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.88440741 |
144 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.85674886 |
145 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.85331941 |
146 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.84781233 |
147 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.84527234 |
148 | FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 0.81544673 |
149 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.81138467 |
150 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 0.80930791 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0008057_abnormal_DNA_replication | 4.55361111 |
2 | MP0004957_abnormal_blastocyst_morpholog | 4.43975240 |
3 | MP0010094_abnormal_chromosome_stability | 4.00264042 |
4 | MP0003693_abnormal_embryo_hatching | 3.94366790 |
5 | MP0003111_abnormal_nucleus_morphology | 3.75977044 |
6 | MP0003077_abnormal_cell_cycle | 3.54140497 |
7 | MP0006292_abnormal_olfactory_placode | 3.06451801 |
8 | MP0003890_abnormal_embryonic-extraembry | 2.70337498 |
9 | MP0010352_gastrointestinal_tract_polyps | 2.62809228 |
10 | MP0008058_abnormal_DNA_repair | 2.55233637 |
11 | MP0003123_paternal_imprinting | 2.51194399 |
12 | MP0004264_abnormal_extraembryonic_tissu | 2.51084064 |
13 | MP0008007_abnormal_cellular_replicative | 2.39623381 |
14 | MP0009697_abnormal_copulation | 2.36740577 |
15 | MP0000350_abnormal_cell_proliferation | 2.28902828 |
16 | MP0003121_genomic_imprinting | 2.27474398 |
17 | MP0008932_abnormal_embryonic_tissue | 2.26240877 |
18 | MP0001672_abnormal_embryogenesis/_devel | 2.16922377 |
19 | MP0005380_embryogenesis_phenotype | 2.16922377 |
20 | MP0001730_embryonic_growth_arrest | 2.08390386 |
21 | MP0002396_abnormal_hematopoietic_system | 2.00560681 |
22 | MP0003984_embryonic_growth_retardation | 1.93187975 |
23 | MP0003941_abnormal_skin_development | 1.91789169 |
24 | MP0002088_abnormal_embryonic_growth/wei | 1.90660524 |
25 | MP0005075_abnormal_melanosome_morpholog | 1.87528604 |
26 | MP0005394_taste/olfaction_phenotype | 1.86353136 |
27 | MP0005499_abnormal_olfactory_system | 1.86353136 |
28 | MP0002009_preneoplasia | 1.80344892 |
29 | MP0002085_abnormal_embryonic_tissue | 1.76438889 |
30 | MP0002084_abnormal_developmental_patter | 1.72140225 |
31 | MP0003786_premature_aging | 1.72044457 |
32 | MP0003567_abnormal_fetal_cardiomyocyte | 1.71727806 |
33 | MP0003195_calcinosis | 1.71455015 |
34 | MP0001293_anophthalmia | 1.70789598 |
35 | MP0000569_abnormal_digit_pigmentation | 1.68337325 |
36 | MP0001697_abnormal_embryo_size | 1.64847492 |
37 | MP0002086_abnormal_extraembryonic_tissu | 1.62534305 |
38 | MP0010307_abnormal_tumor_latency | 1.61797882 |
39 | MP0003011_delayed_dark_adaptation | 1.60175276 |
40 | MP0000490_abnormal_crypts_of | 1.54886833 |
41 | MP0002653_abnormal_ependyma_morphology | 1.54135550 |
42 | MP0003315_abnormal_perineum_morphology | 1.52853584 |
43 | MP0002080_prenatal_lethality | 1.49956514 |
44 | MP0008877_abnormal_DNA_methylation | 1.47854872 |
45 | MP0004197_abnormal_fetal_growth/weight/ | 1.45526557 |
46 | MP0010030_abnormal_orbit_morphology | 1.44483229 |
47 | MP0000313_abnormal_cell_death | 1.43516409 |
48 | MP0000427_abnormal_hair_cycle | 1.43073024 |
49 | MP0002938_white_spotting | 1.38607011 |
50 | MP0003705_abnormal_hypodermis_morpholog | 1.38062831 |
51 | MP0002254_reproductive_system_inflammat | 1.32975902 |
52 | MP0005257_abnormal_intraocular_pressure | 1.32401646 |
53 | MP0001661_extended_life_span | 1.26892757 |
54 | MP0009672_abnormal_birth_weight | 1.26071293 |
55 | MP0006035_abnormal_mitochondrial_morpho | 1.22904109 |
56 | MP0005085_abnormal_gallbladder_physiolo | 1.21802700 |
57 | MP0001849_ear_inflammation | 1.21110989 |
58 | MP0003938_abnormal_ear_development | 1.20015657 |
59 | MP0003122_maternal_imprinting | 1.19770994 |
60 | MP0002092_abnormal_eye_morphology | 1.18700316 |
61 | MP0002102_abnormal_ear_morphology | 1.17461781 |
62 | MP0005395_other_phenotype | 1.16660650 |
63 | MP0004133_heterotaxia | 1.16387246 |
64 | MP0002877_abnormal_melanocyte_morpholog | 1.15863386 |
65 | MP0003937_abnormal_limbs/digits/tail_de | 1.13389720 |
66 | MP0002019_abnormal_tumor_incidence | 1.13101468 |
67 | MP0008789_abnormal_olfactory_epithelium | 1.08726823 |
68 | MP0000383_abnormal_hair_follicle | 1.08350215 |
69 | MP0002210_abnormal_sex_determination | 1.07852102 |
70 | MP0002332_abnormal_exercise_endurance | 1.07794117 |
71 | MP0003787_abnormal_imprinting | 1.06038655 |
72 | MP0000428_abnormal_craniofacial_morphol | 1.05722452 |
73 | MP0001145_abnormal_male_reproductive | 1.05581665 |
74 | MP0003646_muscle_fatigue | 1.05493330 |
75 | MP0004233_abnormal_muscle_weight | 1.05385758 |
76 | MP0003119_abnormal_digestive_system | 1.03628594 |
77 | MP0010678_abnormal_skin_adnexa | 1.00433446 |
78 | MP0000678_abnormal_parathyroid_gland | 0.99702825 |
79 | MP0000432_abnormal_head_morphology | 0.97199848 |
80 | MP0003718_maternal_effect | 0.95787376 |
81 | MP0001764_abnormal_homeostasis | 0.95379570 |
82 | MP0000631_abnormal_neuroendocrine_gland | 0.93529367 |
83 | MP0002127_abnormal_cardiovascular_syste | 0.93468989 |
84 | MP0002233_abnormal_nose_morphology | 0.92602070 |
85 | MP0002114_abnormal_axial_skeleton | 0.92091525 |
86 | MP0001119_abnormal_female_reproductive | 0.90734166 |
87 | MP0006072_abnormal_retinal_apoptosis | 0.90565230 |
88 | MP0009703_decreased_birth_body | 0.90064364 |
89 | MP0002277_abnormal_respiratory_mucosa | 0.88828883 |
90 | MP0004147_increased_porphyrin_level | 0.88781320 |
91 | MP0001929_abnormal_gametogenesis | 0.88288725 |
92 | MP0003698_abnormal_male_reproductive | 0.87883016 |
93 | MP0000358_abnormal_cell_content/ | 0.87685738 |
94 | MP0002932_abnormal_joint_morphology | 0.87320384 |
95 | MP0002234_abnormal_pharynx_morphology | 0.86675512 |
96 | MP0003943_abnormal_hepatobiliary_system | 0.85884469 |
97 | MP0003935_abnormal_craniofacial_develop | 0.84256638 |
98 | MP0003755_abnormal_palate_morphology | 0.84129578 |
99 | MP0000049_abnormal_middle_ear | 0.83715224 |
100 | MP0005551_abnormal_eye_electrophysiolog | 0.83521988 |
101 | MP0003221_abnormal_cardiomyocyte_apopto | 0.82905822 |
102 | MP0005384_cellular_phenotype | 0.82839516 |
103 | MP0005220_abnormal_exocrine_pancreas | 0.82571072 |
104 | MP0005389_reproductive_system_phenotype | 0.82339242 |
105 | MP0005408_hypopigmentation | 0.82264668 |
106 | MP0005646_abnormal_pituitary_gland | 0.81984668 |
107 | MP0005266_abnormal_metabolism | 0.81835534 |
108 | MP0002111_abnormal_tail_morphology | 0.80148071 |
109 | MP0008770_decreased_survivor_rate | 0.79118117 |
110 | MP0004808_abnormal_hematopoietic_stem | 0.78926102 |
111 | MP0001666_abnormal_nutrient_absorption | 0.77728720 |
112 | MP0001286_abnormal_eye_development | 0.76642477 |
113 | MP0000653_abnormal_sex_gland | 0.76159591 |
114 | MP0004043_abnormal_pH_regulation | 0.75707916 |
115 | MP0005253_abnormal_eye_physiology | 0.75413666 |
116 | MP0005647_abnormal_sex_gland | 0.74831407 |
117 | MP0003699_abnormal_female_reproductive | 0.73280811 |
118 | MP0000647_abnormal_sebaceous_gland | 0.72234563 |
119 | MP0000762_abnormal_tongue_morphology | 0.71927521 |
120 | MP0002075_abnormal_coat/hair_pigmentati | 0.70616964 |
121 | MP0002697_abnormal_eye_size | 0.69699339 |
122 | MP0004858_abnormal_nervous_system | 0.69513030 |
123 | MP0000703_abnormal_thymus_morphology | 0.68965066 |
124 | MP0002837_dystrophic_cardiac_calcinosis | 0.68893063 |
125 | MP0001529_abnormal_vocalization | 0.68647264 |
126 | MP0005621_abnormal_cell_physiology | 0.68399586 |
127 | MP0003806_abnormal_nucleotide_metabolis | 0.68322427 |
128 | MP0002160_abnormal_reproductive_system | 0.68254838 |
129 | MP0002925_abnormal_cardiovascular_devel | 0.68129365 |
130 | MP0003861_abnormal_nervous_system | 0.66815177 |
131 | MP0005391_vision/eye_phenotype | 0.66528301 |
132 | MP0005076_abnormal_cell_differentiation | 0.66116942 |
133 | MP0001485_abnormal_pinna_reflex | 0.65009437 |
134 | MP0004215_abnormal_myocardial_fiber | 0.64472102 |
135 | MP0003136_yellow_coat_color | 0.64253805 |
136 | MP0005023_abnormal_wound_healing | 0.63270967 |
137 | MP0002722_abnormal_immune_system | 0.62540702 |
138 | MP0002006_tumorigenesis | 0.62237713 |
139 | MP0000372_irregular_coat_pigmentation | 0.61893344 |
140 | MP0000689_abnormal_spleen_morphology | 0.61572946 |
141 | MP0006054_spinal_hemorrhage | 0.61482075 |
142 | MP0002751_abnormal_autonomic_nervous | 0.61444780 |
143 | MP0005332_abnormal_amino_acid | 0.61031717 |
144 | MP0000858_altered_metastatic_potential | 0.59858974 |
145 | MP0003283_abnormal_digestive_organ | 0.59272486 |
146 | MP0002116_abnormal_craniofacial_bone | 0.59271203 |
147 | MP0009333_abnormal_splenocyte_physiolog | 0.56992909 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ependymoma (HP:0002888) | 4.82170973 |
2 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 4.70150554 |
3 | Chromsome breakage (HP:0040012) | 4.51323642 |
4 | Hypochromic microcytic anemia (HP:0004840) | 4.39645390 |
5 | Bilateral microphthalmos (HP:0007633) | 4.33308174 |
6 | Rhabdomyosarcoma (HP:0002859) | 4.09055164 |
7 | Multiple enchondromatosis (HP:0005701) | 3.87728472 |
8 | Neoplasm of striated muscle (HP:0009728) | 3.60515534 |
9 | Rib fusion (HP:0000902) | 3.55360115 |
10 | Pancreatic islet-cell hyperplasia (HP:0004510) | 3.45058733 |
11 | Medulloblastoma (HP:0002885) | 3.42363113 |
12 | Meckel diverticulum (HP:0002245) | 3.40880267 |
13 | Abnormality of the astrocytes (HP:0100707) | 3.38137623 |
14 | Astrocytoma (HP:0009592) | 3.38137623 |
15 | Nephroblastoma (Wilms tumor) (HP:0002667) | 3.37797725 |
16 | Abnormal lung lobation (HP:0002101) | 3.19871742 |
17 | Abnormality of the ileum (HP:0001549) | 3.19652115 |
18 | Birth length less than 3rd percentile (HP:0003561) | 3.15864592 |
19 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 3.15156205 |
20 | Embryonal renal neoplasm (HP:0011794) | 3.12959696 |
21 | Supernumerary spleens (HP:0009799) | 3.10954969 |
22 | Impulsivity (HP:0100710) | 3.04382949 |
23 | Abnormality of chromosome stability (HP:0003220) | 2.99513932 |
24 | Duodenal stenosis (HP:0100867) | 2.86656186 |
25 | Small intestinal stenosis (HP:0012848) | 2.86656186 |
26 | Abnormality of the preputium (HP:0100587) | 2.86608418 |
27 | Glioma (HP:0009733) | 2.83304089 |
28 | Abnormality of the lower motor neuron (HP:0002366) | 2.82456437 |
29 | Aplasia/hypoplasia of the humerus (HP:0006507) | 2.79911392 |
30 | Hepatoblastoma (HP:0002884) | 2.73790353 |
31 | Trismus (HP:0000211) | 2.70427962 |
32 | Myelodysplasia (HP:0002863) | 2.66406326 |
33 | Biliary tract neoplasm (HP:0100574) | 2.66281137 |
34 | Short humerus (HP:0005792) | 2.60205982 |
35 | Breast hypoplasia (HP:0003187) | 2.59601058 |
36 | Abnormality of the labia minora (HP:0012880) | 2.55910697 |
37 | Neoplasm of the oral cavity (HP:0100649) | 2.52050405 |
38 | Abnormality of the salivary glands (HP:0010286) | 2.51420632 |
39 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 2.51325608 |
40 | Sloping forehead (HP:0000340) | 2.51286294 |
41 | Selective tooth agenesis (HP:0001592) | 2.50597650 |
42 | Abnormality of endocrine pancreas physiology (HP:0012093) | 2.47962783 |
43 | Abnormality of the pancreatic islet cells (HP:0006476) | 2.47962783 |
44 | Pancreatic cysts (HP:0001737) | 2.43381838 |
45 | Atresia of the external auditory canal (HP:0000413) | 2.43230816 |
46 | Fused cervical vertebrae (HP:0002949) | 2.42679638 |
47 | Volvulus (HP:0002580) | 2.41487928 |
48 | Patellar aplasia (HP:0006443) | 2.39979062 |
49 | Rectal fistula (HP:0100590) | 2.39926671 |
50 | Rectovaginal fistula (HP:0000143) | 2.39926671 |
51 | Abnormality of the duodenum (HP:0002246) | 2.31060743 |
52 | Agnosia (HP:0010524) | 2.30231390 |
53 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.29647455 |
54 | Hypoplasia of the fovea (HP:0007750) | 2.29647455 |
55 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.29119024 |
56 | Abnormality of alanine metabolism (HP:0010916) | 2.29119024 |
57 | Hyperalaninemia (HP:0003348) | 2.29119024 |
58 | Abnormal biliary tract morphology (HP:0012440) | 2.27408040 |
59 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.27094584 |
60 | Shawl scrotum (HP:0000049) | 2.26686189 |
61 | Absent radius (HP:0003974) | 2.24338345 |
62 | Preauricular skin tag (HP:0000384) | 2.22925163 |
63 | Glossoptosis (HP:0000162) | 2.22615507 |
64 | Neoplasm of the adrenal cortex (HP:0100641) | 2.20633831 |
65 | Chronic hepatic failure (HP:0100626) | 2.20198435 |
66 | Premature ovarian failure (HP:0008209) | 2.18448620 |
67 | Microretrognathia (HP:0000308) | 2.16902517 |
68 | Clubbing of toes (HP:0100760) | 2.16002056 |
69 | Facial cleft (HP:0002006) | 2.14875428 |
70 | Abnormality of chromosome segregation (HP:0002916) | 2.14586168 |
71 | Bile duct proliferation (HP:0001408) | 2.14478534 |
72 | Abnormal biliary tract physiology (HP:0012439) | 2.14478534 |
73 | Colon cancer (HP:0003003) | 2.13762805 |
74 | Bone marrow hypocellularity (HP:0005528) | 2.13045869 |
75 | Increased nuchal translucency (HP:0010880) | 2.12246609 |
76 | Abnormality of the renal cortex (HP:0011035) | 2.11412633 |
77 | Aplastic anemia (HP:0001915) | 2.11092132 |
78 | Intestinal fistula (HP:0100819) | 2.10634806 |
79 | Missing ribs (HP:0000921) | 2.10525758 |
80 | Aplasia involving forearm bones (HP:0009822) | 2.10428857 |
81 | Absent forearm bone (HP:0003953) | 2.10428857 |
82 | Carpal bone hypoplasia (HP:0001498) | 2.10079616 |
83 | Amyotrophic lateral sclerosis (HP:0007354) | 2.07819288 |
84 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 2.07380912 |
85 | Neoplasm of the small intestine (HP:0100833) | 2.07147108 |
86 | Hyperglycinuria (HP:0003108) | 2.06169540 |
87 | Breast carcinoma (HP:0003002) | 2.04804700 |
88 | Degeneration of anterior horn cells (HP:0002398) | 2.04744527 |
89 | Abnormality of the anterior horn cell (HP:0006802) | 2.04744527 |
90 | Skin tags (HP:0010609) | 2.03910287 |
91 | Cafe-au-lait spot (HP:0000957) | 2.02846398 |
92 | Pancreatic fibrosis (HP:0100732) | 2.01737155 |
93 | Neoplasm of the colon (HP:0100273) | 2.01553187 |
94 | Microvesicular hepatic steatosis (HP:0001414) | 2.01261733 |
95 | Bifid tongue (HP:0010297) | 2.00148348 |
96 | Testicular atrophy (HP:0000029) | 1.98203283 |
97 | Abnormality of the pons (HP:0007361) | 1.98073717 |
98 | Acanthocytosis (HP:0001927) | 1.97504215 |
99 | Ovarian neoplasm (HP:0100615) | 1.97490426 |
100 | Tracheoesophageal fistula (HP:0002575) | 1.95883252 |
101 | Hypochromic anemia (HP:0001931) | 1.95365935 |
102 | Renal cortical cysts (HP:0000803) | 1.95010643 |
103 | Cerebral hypomyelination (HP:0006808) | 1.93041906 |
104 | Tongue fasciculations (HP:0001308) | 1.92086620 |
105 | Hypoplasia of the pons (HP:0012110) | 1.91820699 |
106 | Prominent nose (HP:0000448) | 1.91193109 |
107 | Triphalangeal thumb (HP:0001199) | 1.90953248 |
108 | Urethral obstruction (HP:0000796) | 1.90585010 |
109 | Adenoma sebaceum (HP:0009720) | 1.89545411 |
110 | Angiofibromas (HP:0010615) | 1.89545411 |
111 | Ectopic kidney (HP:0000086) | 1.89437573 |
112 | Progressive inability to walk (HP:0002505) | 1.88654124 |
113 | Abnormality of the carotid arteries (HP:0005344) | 1.88496733 |
114 | Pendular nystagmus (HP:0012043) | 1.88028645 |
115 | Clitoromegaly (HP:0000057) | 1.87476690 |
116 | Homocystinuria (HP:0002156) | 1.86995641 |
117 | Abnormality of homocysteine metabolism (HP:0010919) | 1.86995641 |
118 | Abnormality of the phalanges of the hallux (HP:0010057) | 1.86405103 |
119 | Enlarged kidneys (HP:0000105) | 1.86197716 |
120 | Hypobetalipoproteinemia (HP:0003563) | 1.86089234 |
121 | Large earlobe (HP:0009748) | 1.85788807 |
122 | Vaginal fistula (HP:0004320) | 1.85120996 |
123 | Gaze-evoked nystagmus (HP:0000640) | 1.85028426 |
124 | Spinal muscular atrophy (HP:0007269) | 1.83815862 |
125 | Anal stenosis (HP:0002025) | 1.83481620 |
126 | Abnormality of serum amino acid levels (HP:0003112) | 1.82684608 |
127 | Embryonal neoplasm (HP:0002898) | 1.82497726 |
128 | Absent thumb (HP:0009777) | 1.82171896 |
129 | Abnormality of the nasal septum (HP:0000419) | 1.80556681 |
130 | Reticulocytopenia (HP:0001896) | 1.80300031 |
131 | Neoplasm of the adrenal gland (HP:0100631) | 1.79868880 |
132 | Secondary amenorrhea (HP:0000869) | 1.79431404 |
133 | Malignant neoplasm of the central nervous system (HP:0100836) | 1.79153800 |
134 | Abnormality of glycine metabolism (HP:0010895) | 1.79008031 |
135 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.79008031 |
136 | Hypopigmentation of the fundus (HP:0007894) | 1.78314430 |
137 | Supernumerary ribs (HP:0005815) | 1.77603820 |
138 | Abnormality of methionine metabolism (HP:0010901) | 1.76742261 |
139 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.76683778 |
140 | Gastrointestinal carcinoma (HP:0002672) | 1.76683778 |
141 | Hyperinsulinemic hypoglycemia (HP:0000825) | 1.76155828 |
142 | Type I transferrin isoform profile (HP:0003642) | 1.75994610 |
143 | Progressive muscle weakness (HP:0003323) | 1.75901273 |
144 | Abnormality of the fovea (HP:0000493) | 1.75106832 |
145 | Reduced antithrombin III activity (HP:0001976) | 1.74843571 |
146 | Uterine neoplasm (HP:0010784) | 1.74564937 |
147 | Horseshoe kidney (HP:0000085) | 1.70371118 |
148 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.69998930 |
149 | Fair hair (HP:0002286) | 1.69835294 |
150 | Gonadotropin excess (HP:0000837) | 1.69472190 |
151 | Cupped ear (HP:0000378) | 1.69240560 |
152 | Hyperglycinemia (HP:0002154) | 1.64473827 |
153 | Hypoglycemic coma (HP:0001325) | 1.64062793 |
154 | Dandy-Walker malformation (HP:0001305) | 1.63813362 |
155 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.63513767 |
156 | Neoplasm of the rectum (HP:0100743) | 1.61916613 |
157 | Preaxial hand polydactyly (HP:0001177) | 1.59675555 |
158 | Small hand (HP:0200055) | 1.59627689 |
Rank | Gene Set | Z-score |
---|---|---|
1 | CDK12 | 6.74575483 |
2 | CDC7 | 4.05612090 |
3 | FRK | 3.97782281 |
4 | TTK | 3.58770585 |
5 | BUB1 | 3.53607331 |
6 | WEE1 | 3.30700757 |
7 | NUAK1 | 2.40257550 |
8 | GRK5 | 2.39341949 |
9 | NEK2 | 2.39188257 |
10 | SRPK1 | 2.21023733 |
11 | PLK1 | 2.19984256 |
12 | GRK6 | 2.19156616 |
13 | CDK7 | 2.17192631 |
14 | STK10 | 2.16501497 |
15 | MST4 | 2.05801833 |
16 | TAF1 | 1.99258051 |
17 | CHEK2 | 1.95019115 |
18 | CSF1R | 1.87532278 |
19 | EIF2AK1 | 1.80916067 |
20 | NEK1 | 1.78158989 |
21 | EPHA2 | 1.71729706 |
22 | RPS6KB2 | 1.65065889 |
23 | FGFR2 | 1.55313608 |
24 | AURKB | 1.55180680 |
25 | ACVR1B | 1.54122621 |
26 | PBK | 1.54018953 |
27 | BCR | 1.52596336 |
28 | CHEK1 | 1.52097622 |
29 | BRSK2 | 1.49390672 |
30 | PLK4 | 1.47903738 |
31 | ATR | 1.43710268 |
32 | MAP4K2 | 1.39727573 |
33 | TYRO3 | 1.37535422 |
34 | PAK4 | 1.35887931 |
35 | WNK3 | 1.33986654 |
36 | MKNK1 | 1.30738477 |
37 | BMPR1B | 1.30346604 |
38 | TGFBR2 | 1.30286239 |
39 | GRK1 | 1.29029844 |
40 | VRK1 | 1.26864553 |
41 | PLK3 | 1.26367716 |
42 | TRIM28 | 1.25862244 |
43 | EIF2AK3 | 1.24330943 |
44 | ERN1 | 1.23402287 |
45 | DYRK3 | 1.23128680 |
46 | AURKA | 1.22343127 |
47 | ADRBK2 | 1.20308139 |
48 | TLK1 | 1.18921883 |
49 | NLK | 1.17808242 |
50 | MKNK2 | 1.17562610 |
51 | ALK | 1.16361533 |
52 | CDK4 | 1.16109375 |
53 | EEF2K | 1.15787140 |
54 | MATK | 1.12489747 |
55 | MOS | 1.10506843 |
56 | FGFR1 | 1.07332119 |
57 | ATM | 1.07318316 |
58 | TSSK6 | 1.07153899 |
59 | CAMK1D | 1.03883973 |
60 | CAMK1G | 1.01763237 |
61 | SCYL2 | 1.00040631 |
62 | MAPK7 | 0.97851740 |
63 | MAP3K8 | 0.97732992 |
64 | * CDK2 | 0.97727546 |
65 | PASK | 0.96388857 |
66 | STK39 | 0.96211444 |
67 | CSNK1G1 | 0.92045308 |
68 | TNIK | 0.90902306 |
69 | TESK2 | 0.90674962 |
70 | CSNK1A1L | 0.89537392 |
71 | BRSK1 | 0.89323611 |
72 | ERBB3 | 0.89016562 |
73 | INSRR | 0.85053054 |
74 | MAP3K4 | 0.84407241 |
75 | LATS1 | 0.83522266 |
76 | GRK7 | 0.81158674 |
77 | ZAK | 0.80688358 |
78 | EIF2AK2 | 0.79463976 |
79 | RPS6KA4 | 0.78438280 |
80 | MELK | 0.78184835 |
81 | STK4 | 0.74726446 |
82 | STK3 | 0.73397313 |
83 | CDK1 | 0.73009541 |
84 | PNCK | 0.72324176 |
85 | BRD4 | 0.71173069 |
86 | AKT3 | 0.70553238 |
87 | MAP3K10 | 0.67012991 |
88 | CDK8 | 0.67012046 |
89 | CSNK1G2 | 0.65585157 |
90 | WNK4 | 0.64041074 |
91 | NME2 | 0.63881409 |
92 | STK24 | 0.63617420 |
93 | AKT2 | 0.63543419 |
94 | PRKG2 | 0.63144451 |
95 | PAK1 | 0.62530656 |
96 | CSNK1G3 | 0.61814659 |
97 | OXSR1 | 0.61262816 |
98 | MAPKAPK3 | 0.59507448 |
99 | VRK2 | 0.59301627 |
100 | WNK1 | 0.58887470 |
101 | PLK2 | 0.57352322 |
102 | LATS2 | 0.56304788 |
103 | CSNK1E | 0.55119660 |
104 | CAMKK2 | 0.54578163 |
105 | FLT3 | 0.53869527 |
106 | MAP3K9 | 0.52595702 |
107 | MTOR | 0.51052169 |
108 | CSNK2A2 | 0.50194510 |
109 | PIM1 | 0.50095703 |
110 | CCNB1 | 0.48343869 |
111 | PRKAA2 | 0.47734139 |
112 | PRKCI | 0.47654306 |
113 | NME1 | 0.45639838 |
114 | RPS6KB1 | 0.45514107 |
115 | CLK1 | 0.45504624 |
116 | STK38L | 0.45396730 |
117 | CDK6 | 0.44318371 |
118 | CDK9 | 0.44026860 |
119 | PIK3CA | 0.43925213 |
120 | TGFBR1 | 0.43868867 |
121 | CSNK2A1 | 0.40914857 |
122 | MAPKAPK5 | 0.39273595 |
123 | MAPK14 | 0.38902184 |
124 | CDK3 | 0.37785114 |
125 | HIPK2 | 0.37724707 |
126 | NEK6 | 0.37634528 |
127 | TEC | 0.37223500 |
128 | PDK2 | 0.36788362 |
129 | FGFR3 | 0.36773085 |
130 | FER | 0.36521570 |
131 | ADRBK1 | 0.36019936 |
132 | CAMK4 | 0.34801898 |
133 | STK16 | 0.32907932 |
134 | CSNK1D | 0.30248351 |
135 | GSK3B | 0.29959411 |
136 | PRKDC | 0.29459876 |
137 | PDK3 | 0.26028934 |
138 | PDK4 | 0.26028934 |
139 | MARK2 | 0.25635962 |
140 | MAPK10 | 0.25042577 |
141 | MAPK1 | 0.24679492 |
142 | DYRK2 | 0.22094087 |
143 | RPS6KA5 | 0.19811155 |
144 | AKT1 | 0.19328772 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 4.62882216 |
2 | DNA replication_Homo sapiens_hsa03030 | 4.54825081 |
3 | Mismatch repair_Homo sapiens_hsa03430 | 4.10032399 |
4 | RNA transport_Homo sapiens_hsa03013 | 3.37052294 |
5 | Spliceosome_Homo sapiens_hsa03040 | 2.99914992 |
6 | Homologous recombination_Homo sapiens_hsa03440 | 2.81917390 |
7 | * Cell cycle_Homo sapiens_hsa04110 | 2.80740605 |
8 | RNA polymerase_Homo sapiens_hsa03020 | 2.75992564 |
9 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 2.75056764 |
10 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.69104815 |
11 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.68701081 |
12 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.60210508 |
13 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.53894458 |
14 | Base excision repair_Homo sapiens_hsa03410 | 2.51796759 |
15 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.49347613 |
16 | Ribosome_Homo sapiens_hsa03010 | 2.34094998 |
17 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.20772830 |
18 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 2.16140003 |
19 | RNA degradation_Homo sapiens_hsa03018 | 2.06190362 |
20 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.96695060 |
21 | Basal transcription factors_Homo sapiens_hsa03022 | 1.96477412 |
22 | Proteasome_Homo sapiens_hsa03050 | 1.88463262 |
23 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.75157319 |
24 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.72336950 |
25 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.59152997 |
26 | Lysine degradation_Homo sapiens_hsa00310 | 1.49586874 |
27 | Protein export_Homo sapiens_hsa03060 | 1.47697744 |
28 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.40251349 |
29 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.39528928 |
30 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.39441798 |
31 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.35815210 |
32 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.34511018 |
33 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.30475074 |
34 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.25185152 |
35 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.25151568 |
36 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.18843352 |
37 | Thyroid cancer_Homo sapiens_hsa05216 | 1.18776529 |
38 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.16064653 |
39 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.07406121 |
40 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.03326190 |
41 | Purine metabolism_Homo sapiens_hsa00230 | 1.03203141 |
42 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.03183393 |
43 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.01863777 |
44 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.00345686 |
45 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.99938872 |
46 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.99066817 |
47 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.96919526 |
48 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.95851636 |
49 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.94977732 |
50 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.94925160 |
51 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.93049199 |
52 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.93021761 |
53 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.91936140 |
54 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.91650659 |
55 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.90538929 |
56 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.90479923 |
57 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.90269331 |
58 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.87072502 |
59 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.86694029 |
60 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.86094185 |
61 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.85308705 |
62 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.80502688 |
63 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.75573878 |
64 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.74534483 |
65 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.74281557 |
66 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.73565214 |
67 | Galactose metabolism_Homo sapiens_hsa00052 | 0.73459275 |
68 | HTLV-I infection_Homo sapiens_hsa05166 | 0.72515062 |
69 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.71183525 |
70 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.70790191 |
71 | Phototransduction_Homo sapiens_hsa04744 | 0.70030359 |
72 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.68780027 |
73 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.65393070 |
74 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.63904016 |
75 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.63794239 |
76 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.63658277 |
77 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.61806033 |
78 | Circadian rhythm_Homo sapiens_hsa04710 | 0.60496045 |
79 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.60363204 |
80 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.59986125 |
81 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.59849678 |
82 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.59634558 |
83 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.58769652 |
84 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.58607044 |
85 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.57554499 |
86 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.54856933 |
87 | Alcoholism_Homo sapiens_hsa05034 | 0.53685502 |
88 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.53415792 |
89 | Colorectal cancer_Homo sapiens_hsa05210 | 0.52019107 |
90 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.51145918 |
91 | Apoptosis_Homo sapiens_hsa04210 | 0.51052253 |
92 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.50511900 |
93 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.50203884 |
94 | Metabolic pathways_Homo sapiens_hsa01100 | 0.50179826 |
95 | Retinol metabolism_Homo sapiens_hsa00830 | 0.50127538 |
96 | Pathways in cancer_Homo sapiens_hsa05200 | 0.49723802 |
97 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.44441826 |
98 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.44156595 |
99 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.43689784 |
100 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.43324414 |
101 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.42783970 |
102 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.42758733 |
103 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.41946475 |
104 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.41341383 |
105 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.41145668 |
106 | Sulfur relay system_Homo sapiens_hsa04122 | 0.40736132 |
107 | Peroxisome_Homo sapiens_hsa04146 | 0.39776096 |
108 | ABC transporters_Homo sapiens_hsa02010 | 0.38559923 |
109 | Bladder cancer_Homo sapiens_hsa05219 | 0.36491738 |
110 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.36167281 |
111 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.35275442 |
112 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.34543702 |
113 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.33320611 |
114 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.32622392 |
115 | Taste transduction_Homo sapiens_hsa04742 | 0.32179127 |
116 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.31534042 |
117 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.31383606 |
118 | Legionellosis_Homo sapiens_hsa05134 | 0.31173184 |
119 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.29593988 |
120 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.29592372 |
121 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.28517061 |
122 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.27666194 |
123 | Other glycan degradation_Homo sapiens_hsa00511 | 0.27613708 |
124 | Adherens junction_Homo sapiens_hsa04520 | 0.27279264 |
125 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.27060494 |
126 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.27012928 |
127 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.25359619 |
128 | Tight junction_Homo sapiens_hsa04530 | 0.24970016 |
129 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.24471800 |
130 | Hepatitis B_Homo sapiens_hsa05161 | 0.22965417 |
131 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.22221488 |
132 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.22097127 |
133 | Prostate cancer_Homo sapiens_hsa05215 | 0.21594783 |
134 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.21464174 |
135 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.21399073 |
136 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.20878682 |
137 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.20509110 |
138 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.20219958 |
139 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.20129830 |
140 | Influenza A_Homo sapiens_hsa05164 | 0.19557237 |
141 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.19218988 |
142 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.18523584 |
143 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.17316808 |
144 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.16630658 |
145 | Melanoma_Homo sapiens_hsa05218 | 0.14813360 |
146 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.12606929 |
147 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.11295692 |
148 | Carbon metabolism_Homo sapiens_hsa01200 | 0.10531924 |
149 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.09341698 |
150 | Endometrial cancer_Homo sapiens_hsa05213 | 0.09323121 |
151 | Measles_Homo sapiens_hsa05162 | 0.08883033 |
152 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.08536818 |
153 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.07935259 |