Rank | Gene Set | Z-score |
---|---|---|
1 | exogenous drug catabolic process (GO:0042738) | 8.10563003 |
2 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 7.53328066 |
3 | L-phenylalanine catabolic process (GO:0006559) | 7.53328066 |
4 | epoxygenase P450 pathway (GO:0019373) | 7.53032721 |
5 | omega-hydroxylase P450 pathway (GO:0097267) | 7.38003123 |
6 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 7.21471021 |
7 | L-phenylalanine metabolic process (GO:0006558) | 7.21471021 |
8 | aromatic amino acid family catabolic process (GO:0009074) | 6.73733339 |
9 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 6.20027667 |
10 | tryptophan catabolic process (GO:0006569) | 6.10110182 |
11 | indole-containing compound catabolic process (GO:0042436) | 6.10110182 |
12 | indolalkylamine catabolic process (GO:0046218) | 6.10110182 |
13 | kynurenine metabolic process (GO:0070189) | 5.88786092 |
14 | urea metabolic process (GO:0019627) | 5.78055337 |
15 | urea cycle (GO:0000050) | 5.78055337 |
16 | regulation of plasminogen activation (GO:0010755) | 5.73061984 |
17 | tryptophan metabolic process (GO:0006568) | 5.71239514 |
18 | bile acid biosynthetic process (GO:0006699) | 5.70649134 |
19 | negative regulation of fibrinolysis (GO:0051918) | 5.67457657 |
20 | complement activation, alternative pathway (GO:0006957) | 5.66995185 |
21 | glyoxylate metabolic process (GO:0046487) | 5.57291949 |
22 | regulation of protein activation cascade (GO:2000257) | 5.55474103 |
23 | high-density lipoprotein particle remodeling (GO:0034375) | 5.54999662 |
24 | drug metabolic process (GO:0017144) | 5.49896953 |
25 | regulation of fibrinolysis (GO:0051917) | 5.44144046 |
26 | protein carboxylation (GO:0018214) | 5.35723311 |
27 | peptidyl-glutamic acid carboxylation (GO:0017187) | 5.35723311 |
28 | alpha-linolenic acid metabolic process (GO:0036109) | 5.31237338 |
29 | nitrogen cycle metabolic process (GO:0071941) | 5.31033040 |
30 | oxidative demethylation (GO:0070989) | 5.30800956 |
31 | regulation of humoral immune response (GO:0002920) | 5.28011149 |
32 | cysteine metabolic process (GO:0006534) | 5.27183373 |
33 | sulfur amino acid catabolic process (GO:0000098) | 5.25827212 |
34 | regulation of complement activation (GO:0030449) | 5.17443016 |
35 | regulation of triglyceride catabolic process (GO:0010896) | 5.04022776 |
36 | negative regulation of blood coagulation (GO:0030195) | 4.99537017 |
37 | negative regulation of hemostasis (GO:1900047) | 4.99537017 |
38 | serine family amino acid catabolic process (GO:0009071) | 4.97332691 |
39 | regulation of cholesterol esterification (GO:0010872) | 4.89177114 |
40 | aromatic amino acid family metabolic process (GO:0009072) | 4.87905543 |
41 | bile acid metabolic process (GO:0008206) | 4.87164028 |
42 | reverse cholesterol transport (GO:0043691) | 4.82361686 |
43 | tyrosine metabolic process (GO:0006570) | 4.78673236 |
44 | macromolecular complex remodeling (GO:0034367) | 4.75826234 |
45 | plasma lipoprotein particle remodeling (GO:0034369) | 4.75826234 |
46 | protein-lipid complex remodeling (GO:0034368) | 4.75826234 |
47 | phospholipid efflux (GO:0033700) | 4.74947339 |
48 | phenylpropanoid metabolic process (GO:0009698) | 4.73351899 |
49 | positive regulation of heterotypic cell-cell adhesion (GO:0034116) | 4.71546802 |
50 | homocysteine metabolic process (GO:0050667) | 4.71195929 |
51 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 4.68966746 |
52 | acylglycerol homeostasis (GO:0055090) | 4.68593187 |
53 | triglyceride homeostasis (GO:0070328) | 4.68593187 |
54 | negative regulation of coagulation (GO:0050819) | 4.54288887 |
55 | ethanol metabolic process (GO:0006067) | 4.54005842 |
56 | alpha-amino acid catabolic process (GO:1901606) | 4.53355246 |
57 | negative regulation of wound healing (GO:0061045) | 4.52890636 |
58 | positive regulation of hemostasis (GO:1900048) | 4.49285032 |
59 | positive regulation of blood coagulation (GO:0030194) | 4.49285032 |
60 | plasma lipoprotein particle clearance (GO:0034381) | 4.45948460 |
61 | negative regulation of sterol transport (GO:0032372) | 4.44160771 |
62 | negative regulation of cholesterol transport (GO:0032375) | 4.44160771 |
63 | lysine catabolic process (GO:0006554) | 4.40395660 |
64 | lysine metabolic process (GO:0006553) | 4.40395660 |
65 | amino-acid betaine metabolic process (GO:0006577) | 4.37451029 |
66 | coenzyme catabolic process (GO:0009109) | 4.31013129 |
67 | regulation of apoptotic cell clearance (GO:2000425) | 4.30696230 |
68 | killing of cells in other organism involved in symbiotic interaction (GO:0051883) | 4.29129388 |
69 | disruption of cells of other organism involved in symbiotic interaction (GO:0051818) | 4.29129388 |
70 | indolalkylamine metabolic process (GO:0006586) | 4.29125873 |
71 | bile acid and bile salt transport (GO:0015721) | 4.24941026 |
72 | amine catabolic process (GO:0009310) | 4.21732771 |
73 | cellular biogenic amine catabolic process (GO:0042402) | 4.21732771 |
74 | S-adenosylmethionine metabolic process (GO:0046500) | 4.20829773 |
75 | glycine metabolic process (GO:0006544) | 4.19201732 |
76 | imidazole-containing compound metabolic process (GO:0052803) | 4.19136657 |
77 | cholesterol efflux (GO:0033344) | 4.15536000 |
78 | cellular amino acid catabolic process (GO:0009063) | 4.15296301 |
79 | fibrinolysis (GO:0042730) | 4.14729571 |
80 | glutamate metabolic process (GO:0006536) | 4.14433350 |
81 | positive regulation of coagulation (GO:0050820) | 4.12819463 |
82 | benzene-containing compound metabolic process (GO:0042537) | 4.06733021 |
83 | arginine metabolic process (GO:0006525) | 4.06138878 |
84 | negative regulation of complement activation (GO:0045916) | 4.04824827 |
85 | cellular glucuronidation (GO:0052695) | 4.02965522 |
86 | serine family amino acid metabolic process (GO:0009069) | 4.02345501 |
87 | cellular ketone body metabolic process (GO:0046950) | 3.99677752 |
88 | cellular modified amino acid catabolic process (GO:0042219) | 3.99464109 |
89 | negative regulation of lipase activity (GO:0060192) | 3.97428032 |
90 | plasma lipoprotein particle assembly (GO:0034377) | 3.96373329 |
91 | * acute-phase response (GO:0006953) | 3.94861308 |
92 | ethanol oxidation (GO:0006069) | 3.94787164 |
93 | intestinal cholesterol absorption (GO:0030299) | 3.91190715 |
94 | alkaloid metabolic process (GO:0009820) | 3.90696120 |
95 | hormone catabolic process (GO:0042447) | 3.90616759 |
96 | heme transport (GO:0015886) | 3.90613852 |
97 | complement activation, classical pathway (GO:0006958) | 3.89958464 |
98 | aldehyde catabolic process (GO:0046185) | 3.88849258 |
99 | * acute inflammatory response (GO:0002526) | 3.88394228 |
100 | dicarboxylic acid biosynthetic process (GO:0043650) | 3.88095981 |
101 | complement activation (GO:0006956) | 3.86870383 |
102 | positive regulation of lipoprotein lipase activity (GO:0051006) | 3.85974317 |
103 | positive regulation of triglyceride lipase activity (GO:0061365) | 3.85974317 |
104 | blood coagulation, intrinsic pathway (GO:0007597) | 3.85120382 |
105 | protein activation cascade (GO:0072376) | 3.83432307 |
106 | cytolysis (GO:0019835) | 3.77414136 |
107 | cofactor catabolic process (GO:0051187) | 3.76561768 |
108 | low-density lipoprotein particle remodeling (GO:0034374) | 3.76406960 |
109 | serine family amino acid biosynthetic process (GO:0009070) | 3.76286975 |
110 | positive regulation of lipid catabolic process (GO:0050996) | 3.75913004 |
111 | positive regulation of fatty acid biosynthetic process (GO:0045723) | 3.74177348 |
112 | acetyl-CoA metabolic process (GO:0006084) | 3.72968023 |
113 | drug catabolic process (GO:0042737) | 3.72610160 |
114 | opsonization (GO:0008228) | 3.71197792 |
115 | very-low-density lipoprotein particle assembly (GO:0034379) | 3.70892347 |
116 | regulation of acute inflammatory response (GO:0002673) | 3.70094517 |
117 | cholesterol homeostasis (GO:0042632) | 3.66528407 |
118 | phospholipid homeostasis (GO:0055091) | 3.65639392 |
119 | flavonoid metabolic process (GO:0009812) | 3.64546270 |
120 | regulation of cholesterol homeostasis (GO:2000188) | 3.64224752 |
121 | carboxylic acid catabolic process (GO:0046395) | 3.61933217 |
122 | organic acid catabolic process (GO:0016054) | 3.61933217 |
123 | regulation of lipoprotein particle clearance (GO:0010984) | 3.61081964 |
124 | sterol homeostasis (GO:0055092) | 3.60867939 |
125 | plasma lipoprotein particle organization (GO:0071827) | 3.59663295 |
126 | negative regulation of protein activation cascade (GO:2000258) | 3.59283545 |
127 | glucuronate metabolic process (GO:0019585) | 3.57091079 |
128 | uronic acid metabolic process (GO:0006063) | 3.57091079 |
129 | protein-lipid complex assembly (GO:0065005) | 3.55293831 |
130 | regulation of bile acid biosynthetic process (GO:0070857) | 3.50833413 |
131 | response to mercury ion (GO:0046689) | 3.48160489 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * RXR_22158963_ChIP-Seq_LIVER_Mouse | 8.13015171 |
2 | * PPARA_22158963_ChIP-Seq_LIVER_Mouse | 6.98365490 |
3 | * EGR1_23403033_ChIP-Seq_LIVER_Mouse | 6.81165288 |
4 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 6.29863002 |
5 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 5.42346409 |
6 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 5.29272163 |
7 | * CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 5.12901863 |
8 | * NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 4.02504505 |
9 | * CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 3.89267858 |
10 | * TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.14693632 |
11 | TCF7L2_21901280_ChIP-Seq_H4IIE_Rat | 2.01246505 |
12 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 11.7913007 |
13 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.91259711 |
14 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.73771231 |
15 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.57461003 |
16 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.54620142 |
17 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.48117091 |
18 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.40596010 |
19 | GATA1_22025678_ChIP-Seq_K562_Human | 1.37592373 |
20 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.37123495 |
21 | * HNF4A_19822575_ChIP-Seq_HepG2_Human | 1.33715311 |
22 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.29260865 |
23 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.24569770 |
24 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.20388623 |
25 | RXRA_24833708_ChIP-Seq_LIVER_Mouse | 1.16454685 |
26 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.13428339 |
27 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.07988955 |
28 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.01841177 |
29 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.00187584 |
30 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 0.95738130 |
31 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.94172785 |
32 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.92561065 |
33 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 0.92325358 |
34 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 0.88143329 |
35 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.86064408 |
36 | GATA4_25053715_ChIP-Seq_YYC3_Human | 0.85603030 |
37 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.83637425 |
38 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.83101682 |
39 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.82040652 |
40 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.81914885 |
41 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.80603400 |
42 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.79232666 |
43 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.79061514 |
44 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 0.78049620 |
45 | * RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 0.71702794 |
46 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 0.71120112 |
47 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.70314114 |
48 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.70314114 |
49 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.69739941 |
50 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.69297762 |
51 | RARA_24833708_ChIP-Seq_LIVER_Mouse | 0.69197481 |
52 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.69147778 |
53 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.68876257 |
54 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 0.68651011 |
55 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.68508106 |
56 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.67486019 |
57 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 0.67060807 |
58 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.66363892 |
59 | * SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.66243909 |
60 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 0.65325199 |
61 | SOX2_21211035_ChIP-Seq_LN229_Human | 0.65088921 |
62 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.63842580 |
63 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 0.63703928 |
64 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 0.60245601 |
65 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.59164044 |
66 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 0.58908851 |
67 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.58149645 |
68 | * RARB_24833708_ChIP-Seq_LIVER_Mouse | 0.57607862 |
69 | HNFA_21074721_ChIP-Seq_CACO-2_Human | 0.57336032 |
70 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 0.57332531 |
71 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.56512000 |
72 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.56141337 |
73 | SMC4_20622854_ChIP-Seq_HELA_Human | 0.55525317 |
74 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 0.55147051 |
75 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 0.54637781 |
76 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.54239837 |
77 | AR_20517297_ChIP-Seq_VCAP_Human | 0.53834159 |
78 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.53679547 |
79 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 0.53511287 |
80 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.52463999 |
81 | POU5F1_16518401_ChIP-PET_MESCs_Mouse | 0.51738861 |
82 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.51547737 |
83 | PPARG_20887899_ChIP-Seq_3T3-L1_Mouse | 0.51140457 |
84 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.50974966 |
85 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.50770911 |
86 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.50395845 |
87 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.50017865 |
88 | FOXA1_26743006_Chip-Seq_LNCaP-abl_Human | 0.49927178 |
89 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.49628051 |
90 | CBP_21632823_ChIP-Seq_H3396_Human | 0.49566995 |
91 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 0.49530439 |
92 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.49413070 |
93 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.49317177 |
94 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.49185537 |
95 | * PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.48977541 |
96 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 0.48752505 |
97 | MYC_19915707_ChIP-ChIP_AK7_Human | 0.48710138 |
98 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.48159572 |
99 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.47480281 |
100 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.47419659 |
101 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.47264527 |
102 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.47055657 |
103 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.45943421 |
104 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.45374869 |
105 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.45128002 |
106 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.45028526 |
107 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 0.44470064 |
108 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.44258575 |
109 | ESET_19884257_ChIP-Seq_ESCs_Mouse | 0.44116819 |
110 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.43787967 |
111 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.43703807 |
112 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.43641420 |
113 | GATA6_25053715_ChIP-Seq_YYC3_Human | 0.43532936 |
114 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.42861541 |
115 | STAT1_17558387_ChIP-Seq_HELA_Human | 0.42827032 |
116 | GATA3_24758297_ChIP-Seq_MCF-7_Human | 0.41849201 |
117 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 0.40296836 |
118 | GATA2_19941826_ChIP-Seq_K562_Human | 0.39805693 |
119 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.39367059 |
120 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.38078166 |
121 | GATA1_19941826_ChIP-Seq_K562_Human | 0.37808488 |
122 | CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.36807313 |
123 | MYC_27129775_Chip-Seq_CORNEA_Mouse | 0.36798571 |
124 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.36604503 |
125 | STAT3_19079543_ChIP-ChIP_MESCs_Mouse | 0.36345046 |
126 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.35405468 |
127 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.35334659 |
128 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.35279762 |
129 | CSB_26484114_Chip-Seq_FIBROBLAST_Human | 0.35147932 |
130 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 0.34983678 |
131 | P63_20808887_ChIP-Seq_KERATINOCYTES_Human | 0.34777211 |
132 | GATA3_20176728_ChIP-ChIP_TSCs_Mouse | 0.34191695 |
133 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.33805796 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0002139_abnormal_hepatobiliary_system | 8.05836707 |
2 | MP0005360_urolithiasis | 7.34262621 |
3 | MP0005085_abnormal_gallbladder_physiolo | 6.27143631 |
4 | MP0005365_abnormal_bile_salt | 6.02596885 |
5 | MP0008875_abnormal_xenobiotic_pharmacok | 4.97236058 |
6 | MP0003806_abnormal_nucleotide_metabolis | 3.98981187 |
7 | MP0003252_abnormal_bile_duct | 3.71473591 |
8 | MP0010329_abnormal_lipoprotein_level | 3.62454851 |
9 | MP0009840_abnormal_foam_cell | 3.34110623 |
10 | MP0005083_abnormal_biliary_tract | 2.94054766 |
11 | MP0003191_abnormal_cellular_cholesterol | 2.90684514 |
12 | MP0003195_calcinosis | 2.75264478 |
13 | MP0005332_abnormal_amino_acid | 2.70618504 |
14 | MP0001666_abnormal_nutrient_absorption | 2.52987088 |
15 | MP0000609_abnormal_liver_physiology | 2.19017303 |
16 | MP0004019_abnormal_vitamin_homeostasis | 2.16066074 |
17 | MP0002118_abnormal_lipid_homeostasis | 2.14949411 |
18 | MP0002138_abnormal_hepatobiliary_system | 1.91493607 |
19 | MP0005319_abnormal_enzyme/_coenzyme | 1.79894693 |
20 | MP0003868_abnormal_feces_composition | 1.75942159 |
21 | MP0003011_delayed_dark_adaptation | 1.72189255 |
22 | MP0001764_abnormal_homeostasis | 1.62344032 |
23 | MP0005451_abnormal_body_composition | 1.58165934 |
24 | MP0005584_abnormal_enzyme/coenzyme_acti | 1.56270061 |
25 | MP0009697_abnormal_copulation | 1.43303779 |
26 | MP0003186_abnormal_redox_activity | 1.30429389 |
27 | MP0003705_abnormal_hypodermis_morpholog | 1.29017061 |
28 | MP0002254_reproductive_system_inflammat | 1.24598327 |
29 | MP0009643_abnormal_urine_homeostasis | 1.23348198 |
30 | MP0002132_abnormal_respiratory_system | 1.19709009 |
31 | MP0005670_abnormal_white_adipose | 1.18694891 |
32 | MP0003656_abnormal_erythrocyte_physiolo | 1.16817309 |
33 | MP0000598_abnormal_liver_morphology | 1.15774322 |
34 | MP0000604_amyloidosis | 1.14404351 |
35 | MP0009764_decreased_sensitivity_to | 1.12112709 |
36 | MP0005647_abnormal_sex_gland | 1.12084058 |
37 | MP0009763_increased_sensitivity_to | 1.06970137 |
38 | MP0001915_intracranial_hemorrhage | 1.00202929 |
39 | MP0005636_abnormal_mineral_homeostasis | 0.93589903 |
40 | MP0002796_impaired_skin_barrier | 0.92492842 |
41 | MP0008469_abnormal_protein_level | 0.91949976 |
42 | MP0002971_abnormal_brown_adipose | 0.87532646 |
43 | MP0009642_abnormal_blood_homeostasis | 0.86954399 |
44 | MP0010368_abnormal_lymphatic_system | 0.86074685 |
45 | MP0004130_abnormal_muscle_cell | 0.82016617 |
46 | MP0002876_abnormal_thyroid_physiology | 0.81453770 |
47 | MP0009765_abnormal_xenobiotic_induced | 0.80786115 |
48 | MP0005408_hypopigmentation | 0.78632797 |
49 | MP0006036_abnormal_mitochondrial_physio | 0.77162733 |
50 | MP0002078_abnormal_glucose_homeostasis | 0.76786368 |
51 | MP0005376_homeostasis/metabolism_phenot | 0.76566176 |
52 | MP0005334_abnormal_fat_pad | 0.76555179 |
53 | MP0003690_abnormal_glial_cell | 0.72912162 |
54 | MP0003879_abnormal_hair_cell | 0.71464666 |
55 | MP0001661_extended_life_span | 0.71376365 |
56 | MP0002282_abnormal_trachea_morphology | 0.71162256 |
57 | MP0005220_abnormal_exocrine_pancreas | 0.71118896 |
58 | MP0005535_abnormal_body_temperature | 0.69694718 |
59 | MP0005058_abnormal_lysosome_morphology | 0.68966466 |
60 | MP0005187_abnormal_penis_morphology | 0.66419554 |
61 | MP0000566_synostosis | 0.66205643 |
62 | MP0009785_altered_susceptibility_to | 0.65975520 |
63 | MP0009053_abnormal_anal_canal | 0.65251039 |
64 | MP0005666_abnormal_adipose_tissue | 0.65135266 |
65 | MP0005084_abnormal_gallbladder_morpholo | 0.65083614 |
66 | MP0003329_amyloid_beta_deposits | 0.62280203 |
67 | MP0004381_abnormal_hair_follicle | 0.60225144 |
68 | MP0005023_abnormal_wound_healing | 0.60167558 |
69 | MP0010234_abnormal_vibrissa_follicle | 0.59595757 |
70 | MP0005266_abnormal_metabolism | 0.58029232 |
71 | MP0001756_abnormal_urination | 0.57634950 |
72 | MP0000639_abnormal_adrenal_gland | 0.57521138 |
73 | MP0005464_abnormal_platelet_physiology | 0.57205262 |
74 | MP0005448_abnormal_energy_balance | 0.57196595 |
75 | MP0002249_abnormal_larynx_morphology | 0.56973565 |
76 | MP0003436_decreased_susceptibility_to | 0.55175755 |
77 | MP0003724_increased_susceptibility_to | 0.53395843 |
78 | MP0001881_abnormal_mammary_gland | 0.53179484 |
79 | MP0000579_abnormal_nail_morphology | 0.50907024 |
80 | MP0002060_abnormal_skin_morphology | 0.50357922 |
81 | MP0005395_other_phenotype | 0.49758107 |
82 | MP0006035_abnormal_mitochondrial_morpho | 0.49547077 |
83 | MP0003638_abnormal_response/metabolism_ | 0.48034569 |
84 | MP0008873_increased_physiological_sensi | 0.47581725 |
85 | MP0004782_abnormal_surfactant_physiolog | 0.46777233 |
86 | MP0004883_abnormal_blood_vessel | 0.46695154 |
87 | MP0002136_abnormal_kidney_physiology | 0.46453153 |
88 | MP0003453_abnormal_keratinocyte_physiol | 0.45186822 |
89 | MP0009384_cardiac_valve_regurgitation | 0.44593718 |
90 | MP0002837_dystrophic_cardiac_calcinosis | 0.43957528 |
91 | MP0008874_decreased_physiological_sensi | 0.42714167 |
92 | MP0009115_abnormal_fat_cell | 0.42687048 |
93 | MP0003718_maternal_effect | 0.42651807 |
94 | MP0003075_altered_response_to | 0.41992255 |
95 | MP0005248_abnormal_Harderian_gland | 0.40705838 |
96 | MP0005166_decreased_susceptibility_to | 0.39719542 |
97 | MP0002822_catalepsy | 0.39699888 |
98 | MP0001243_abnormal_dermal_layer | 0.39355195 |
99 | MP0003953_abnormal_hormone_level | 0.38954948 |
100 | MP0002970_abnormal_white_adipose | 0.38832601 |
101 | MP0000427_abnormal_hair_cycle | 0.38669166 |
102 | MP0002089_abnormal_postnatal_growth/wei | 0.38471874 |
103 | MP0002928_abnormal_bile_duct | 0.35536349 |
104 | MP0005501_abnormal_skin_physiology | 0.35401437 |
105 | MP0004185_abnormal_adipocyte_glucose | 0.34994481 |
106 | MP0008872_abnormal_physiological_respon | 0.34803382 |
107 | MP0009672_abnormal_birth_weight | 0.34232832 |
108 | MP0000249_abnormal_blood_vessel | 0.33263663 |
109 | MP0004947_skin_inflammation | 0.31905779 |
110 | MP0001845_abnormal_inflammatory_respons | 0.31791258 |
111 | MP0005164_abnormal_response_to | 0.31693436 |
112 | MP0001851_eye_inflammation | 0.31352751 |
113 | MP0002168_other_aberrant_phenotype | 0.31346986 |
114 | MP0001853_heart_inflammation | 0.30403387 |
115 | MP0000467_abnormal_esophagus_morphology | 0.29566280 |
116 | MP0003172_abnormal_lysosome_physiology | 0.28764258 |
117 | MP0004272_abnormal_basement_membrane | 0.27673716 |
118 | MP0000920_abnormal_myelination | 0.26931790 |
119 | MP0002128_abnormal_blood_circulation | 0.22528472 |
120 | MP0003632_abnormal_nervous_system | 0.21874663 |
121 | MP0002419_abnormal_innate_immunity | 0.21848769 |
122 | MP0001545_abnormal_hematopoietic_system | 0.21206633 |
123 | MP0005397_hematopoietic_system_phenotyp | 0.21206633 |
124 | MP0000858_altered_metastatic_potential | 0.21066805 |
125 | MP0005167_abnormal_blood-brain_barrier | 0.19481359 |
126 | MP0005025_abnormal_response_to | 0.19186177 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 7.33862921 |
2 | Deep venous thrombosis (HP:0002625) | 7.30348443 |
3 | Intrahepatic cholestasis (HP:0001406) | 7.04185922 |
4 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 6.75376488 |
5 | Prolonged partial thromboplastin time (HP:0003645) | 6.52733151 |
6 | Hypobetalipoproteinemia (HP:0003563) | 6.31074289 |
7 | Xanthomatosis (HP:0000991) | 6.23857073 |
8 | Complement deficiency (HP:0004431) | 5.85397605 |
9 | Hyperlipoproteinemia (HP:0010980) | 5.75489295 |
10 | Hypolipoproteinemia (HP:0010981) | 4.79035150 |
11 | Joint hemorrhage (HP:0005261) | 4.76172128 |
12 | Abnormality of the common coagulation pathway (HP:0010990) | 4.69033701 |
13 | Epidermoid cyst (HP:0200040) | 4.60700989 |
14 | Hyperammonemia (HP:0001987) | 4.53412671 |
15 | Abnormality of the level of lipoprotein cholesterol (HP:0010979) | 4.43117627 |
16 | Abnormality of complement system (HP:0005339) | 4.31635228 |
17 | Abnormality of methionine metabolism (HP:0010901) | 4.28881682 |
18 | Hypoalphalipoproteinemia (HP:0003233) | 4.25405284 |
19 | Hyperglycinemia (HP:0002154) | 4.22772939 |
20 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 4.21570522 |
21 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 4.19956268 |
22 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 4.13461238 |
23 | Ketosis (HP:0001946) | 4.10907221 |
24 | Fat malabsorption (HP:0002630) | 4.00182373 |
25 | Hyperglycinuria (HP:0003108) | 3.79584848 |
26 | Abnormality of pyrimidine metabolism (HP:0004353) | 3.78126217 |
27 | Abnormality of the intrinsic pathway (HP:0010989) | 3.76569135 |
28 | Abnormality of glycine metabolism (HP:0010895) | 3.76314613 |
29 | Abnormality of serine family amino acid metabolism (HP:0010894) | 3.76314613 |
30 | Hypoglycemic coma (HP:0001325) | 3.72074359 |
31 | Hypercholesterolemia (HP:0003124) | 3.55830637 |
32 | Spontaneous abortion (HP:0005268) | 3.51145800 |
33 | Conjugated hyperbilirubinemia (HP:0002908) | 3.50046149 |
34 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 3.27380940 |
35 | Abnormality of fatty-acid metabolism (HP:0004359) | 3.24385113 |
36 | Hyperbilirubinemia (HP:0002904) | 3.14057259 |
37 | Steatorrhea (HP:0002570) | 3.06881386 |
38 | Myocardial infarction (HP:0001658) | 3.03275179 |
39 | Abnormality of nucleobase metabolism (HP:0010932) | 3.02929684 |
40 | Abnormality of serum amino acid levels (HP:0003112) | 2.99658033 |
41 | Systemic lupus erythematosus (HP:0002725) | 2.98062144 |
42 | Purpura (HP:0000979) | 2.92775164 |
43 | Hepatocellular carcinoma (HP:0001402) | 2.86775477 |
44 | Ketoacidosis (HP:0001993) | 2.86582177 |
45 | Skin nodule (HP:0200036) | 2.81566431 |
46 | Delayed CNS myelination (HP:0002188) | 2.81152194 |
47 | Hypochromic microcytic anemia (HP:0004840) | 2.73534158 |
48 | Amyloidosis (HP:0011034) | 2.66672735 |
49 | Abnormality of purine metabolism (HP:0004352) | 2.65331418 |
50 | Metabolic acidosis (HP:0001942) | 2.64214550 |
51 | Glomerulonephritis (HP:0000099) | 2.61778910 |
52 | Cholecystitis (HP:0001082) | 2.60825553 |
53 | Abnormal gallbladder physiology (HP:0012438) | 2.60825553 |
54 | Lethargy (HP:0001254) | 2.57889386 |
55 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.57361539 |
56 | Osteomalacia (HP:0002749) | 2.56704581 |
57 | Vascular calcification (HP:0004934) | 2.54011164 |
58 | Gingival bleeding (HP:0000225) | 2.49200838 |
59 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.47152870 |
60 | Dicarboxylic aciduria (HP:0003215) | 2.47152870 |
61 | Pulmonary embolism (HP:0002204) | 2.46439790 |
62 | Abnormal gallbladder morphology (HP:0012437) | 2.45686296 |
63 | Cerebral edema (HP:0002181) | 2.40705984 |
64 | Cholelithiasis (HP:0001081) | 2.39522814 |
65 | Spastic diplegia (HP:0001264) | 2.39044570 |
66 | Acanthocytosis (HP:0001927) | 2.38926972 |
67 | Mitral stenosis (HP:0001718) | 2.38280386 |
68 | Gout (HP:0001997) | 2.36028051 |
69 | Neonatal onset (HP:0003623) | 2.34341618 |
70 | Hypoglycemic seizures (HP:0002173) | 2.33084099 |
71 | Irritability (HP:0000737) | 2.32542252 |
72 | Cardiovascular calcification (HP:0011915) | 2.25931969 |
73 | Esophageal varix (HP:0002040) | 2.23481749 |
74 | Thrombophlebitis (HP:0004418) | 2.20152507 |
75 | Reduced antithrombin III activity (HP:0001976) | 2.15779561 |
76 | Malnutrition (HP:0004395) | 2.13392292 |
77 | Pancreatitis (HP:0001733) | 2.13131619 |
78 | Menorrhagia (HP:0000132) | 2.12175429 |
79 | Brushfield spots (HP:0001088) | 2.12141155 |
80 | Late onset (HP:0003584) | 2.11658934 |
81 | Joint swelling (HP:0001386) | 2.07263393 |
82 | Sensorimotor neuropathy (HP:0007141) | 2.05778921 |
83 | Vomiting (HP:0002013) | 2.04539579 |
84 | Gangrene (HP:0100758) | 2.02783889 |
85 | Abnormality of iron homeostasis (HP:0011031) | 2.02608204 |
86 | Enlarged kidneys (HP:0000105) | 2.00577254 |
87 | Abnormality of the gallbladder (HP:0005264) | 2.00429148 |
88 | Epistaxis (HP:0000421) | 1.99817558 |
89 | Increased serum ferritin (HP:0003281) | 1.97627597 |
90 | Hemorrhage of the eye (HP:0011885) | 1.96962417 |
91 | Opisthotonus (HP:0002179) | 1.96960121 |
92 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.96444739 |
93 | Fair hair (HP:0002286) | 1.95175105 |
94 | Abnormal cartilage morphology (HP:0002763) | 1.94455995 |
95 | Nephritis (HP:0000123) | 1.92156742 |
96 | Arthropathy (HP:0003040) | 1.91844587 |
97 | Rickets (HP:0002748) | 1.91613551 |
98 | Generalized aminoaciduria (HP:0002909) | 1.90652102 |
99 | Abnormality of the Achilles tendon (HP:0005109) | 1.90392058 |
100 | Abnormality of proline metabolism (HP:0010907) | 1.90296683 |
101 | Hydroxyprolinuria (HP:0003080) | 1.90296683 |
102 | Hyperinsulinemic hypoglycemia (HP:0000825) | 1.87468879 |
103 | Hypophosphatemic rickets (HP:0004912) | 1.85564902 |
104 | Bifid scrotum (HP:0000048) | 1.85149800 |
105 | Elevated alkaline phosphatase (HP:0003155) | 1.84467449 |
106 | Hyperphosphaturia (HP:0003109) | 1.84348545 |
107 | Poikilocytosis (HP:0004447) | 1.80162865 |
108 | Alkalosis (HP:0001948) | 1.78167634 |
109 | Hypertriglyceridemia (HP:0002155) | 1.77989213 |
110 | Elevated hepatic transaminases (HP:0002910) | 1.77172164 |
111 | Abnormal enzyme/coenzyme activity (HP:0012379) | 1.76772534 |
112 | Abnormal delivery (HP:0001787) | 1.75588713 |
113 | Hyperglycemia (HP:0003074) | 1.74471616 |
114 | Renal cortical cysts (HP:0000803) | 1.72280925 |
115 | Neonatal hypoglycemia (HP:0001998) | 1.71006884 |
116 | Abnormality of vitamin metabolism (HP:0100508) | 1.69725945 |
117 | Abnormality of alkaline phosphatase activity (HP:0004379) | 1.69556895 |
118 | Glycosuria (HP:0003076) | 1.65817647 |
119 | Abnormality of urine glucose concentration (HP:0011016) | 1.65817647 |
120 | Increased mean platelet volume (HP:0011877) | 1.63213060 |
121 | Increased serum pyruvate (HP:0003542) | 1.58100192 |
122 | Abnormal platelet function (HP:0011869) | 1.52240098 |
123 | Impaired platelet aggregation (HP:0003540) | 1.52240098 |
124 | Abnormal urine phosphate concentration (HP:0012599) | 1.49826148 |
125 | Abnormal platelet volume (HP:0011876) | 1.49503886 |
126 | Cerebral palsy (HP:0100021) | 1.49133800 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BCKDK | 6.79373577 |
2 | ERN1 | 5.15659370 |
3 | FGFR4 | 4.54111126 |
4 | SIK1 | 4.12787979 |
5 | ERBB4 | 3.17759041 |
6 | INSRR | 2.71150880 |
7 | TAOK3 | 2.69015826 |
8 | MST1R | 2.47233677 |
9 | MAP2K4 | 2.24895112 |
10 | PRPF4B | 2.03098228 |
11 | TRIB3 | 2.00331380 |
12 | LATS1 | 1.92887656 |
13 | MAPK11 | 1.91098644 |
14 | TNK2 | 1.89892255 |
15 | PKN2 | 1.84935521 |
16 | ICK | 1.80383466 |
17 | TYK2 | 1.63403250 |
18 | FLT3 | 1.61499943 |
19 | PIK3CG | 1.60955103 |
20 | PTK6 | 1.55839187 |
21 | NEK9 | 1.53349953 |
22 | ABL2 | 1.45375872 |
23 | NTRK3 | 1.37588099 |
24 | DAPK2 | 1.35899771 |
25 | FRK | 1.35601842 |
26 | FGFR2 | 1.33774878 |
27 | JAK2 | 1.27029102 |
28 | MAP3K3 | 1.24815578 |
29 | MAP3K7 | 1.21070592 |
30 | TBK1 | 1.20081312 |
31 | PRKAA2 | 1.17719804 |
32 | CAMK1D | 1.14674050 |
33 | BLK | 1.13345661 |
34 | KDR | 1.09070548 |
35 | MAP3K14 | 1.07949263 |
36 | ERBB2 | 1.07339215 |
37 | JAK1 | 1.06775999 |
38 | NLK | 1.06649992 |
39 | MAP2K3 | 1.05919613 |
40 | EPHA3 | 1.05584905 |
41 | EPHB1 | 1.04480643 |
42 | GRK6 | 0.97444736 |
43 | STK38L | 0.97441367 |
44 | MET | 0.96175625 |
45 | MAPK4 | 0.95124974 |
46 | WNK4 | 0.92599331 |
47 | PINK1 | 0.92223494 |
48 | PDK2 | 0.89746858 |
49 | ZAP70 | 0.89481258 |
50 | MAP3K11 | 0.88490396 |
51 | RIPK1 | 0.87019844 |
52 | PRKCZ | 0.86249082 |
53 | CDK6 | 0.81342273 |
54 | MAPK12 | 0.76502802 |
55 | CAMK2G | 0.75417415 |
56 | PRKACG | 0.74378493 |
57 | MAPKAPK3 | 0.73583219 |
58 | CAMKK2 | 0.73560851 |
59 | MAPK15 | 0.73422922 |
60 | KSR2 | 0.72483341 |
61 | FGFR3 | 0.71512734 |
62 | IRAK3 | 0.71499022 |
63 | MAP3K10 | 0.71416307 |
64 | TGFBR2 | 0.71182863 |
65 | GSK3A | 0.70860338 |
66 | CDK12 | 0.70741673 |
67 | DYRK1B | 0.69630797 |
68 | MAP2K6 | 0.69531038 |
69 | IKBKE | 0.67219886 |
70 | PRKG1 | 0.65016264 |
71 | CSK | 0.62211622 |
72 | AKT3 | 0.60071100 |
73 | MAP2K1 | 0.59196191 |
74 | PRKAA1 | 0.58238693 |
75 | SGK223 | 0.58146040 |
76 | SGK494 | 0.58146040 |
77 | EIF2AK1 | 0.57967783 |
78 | TIE1 | 0.57827564 |
79 | MAP3K6 | 0.57761871 |
80 | FGFR1 | 0.56445952 |
81 | PTK2 | 0.55836368 |
82 | SGK1 | 0.53304661 |
83 | PRKACA | 0.52730897 |
84 | SCYL2 | 0.52281598 |
85 | MAP3K5 | 0.51180862 |
86 | CAMK1G | 0.50492799 |
87 | PKN1 | 0.50348091 |
88 | CAMKK1 | 0.50258560 |
89 | PDPK1 | 0.50204880 |
90 | CSNK1D | 0.49043684 |
91 | CSNK1E | 0.48908773 |
92 | EEF2K | 0.48543043 |
93 | MAPK7 | 0.48141130 |
94 | SGK3 | 0.47570978 |
95 | IGF1R | 0.44966079 |
96 | CSF1R | 0.43676653 |
97 | SRC | 0.43606831 |
98 | RPS6KA3 | 0.42577714 |
99 | GRK1 | 0.42200230 |
100 | PRKCB | 0.41816754 |
101 | PRKCQ | 0.41780959 |
102 | LATS2 | 0.41274843 |
103 | PRKACB | 0.38663786 |
104 | EGFR | 0.37326990 |
105 | RET | 0.37326080 |
106 | PDK3 | 0.37064704 |
107 | PDK4 | 0.37064704 |
108 | MAP3K2 | 0.36263932 |
109 | CSNK1G1 | 0.35945586 |
110 | CSNK2A2 | 0.34556323 |
111 | CSNK2A1 | 0.34467549 |
112 | BMX | 0.33818642 |
113 | MTOR | 0.33722431 |
114 | IRAK1 | 0.33663087 |
115 | FER | 0.33650818 |
116 | MAP3K1 | 0.33633894 |
117 | TAOK2 | 0.33285899 |
118 | MAP3K13 | 0.33091008 |
119 | CDK4 | 0.32137586 |
120 | BRSK2 | 0.31736098 |
121 | PRKCG | 0.31147682 |
122 | EPHB2 | 0.30757962 |
123 | EPHA2 | 0.29923580 |
124 | CAMK4 | 0.28973596 |
125 | ABL1 | 0.28378102 |
126 | SGK2 | 0.27363050 |
127 | PDK1 | 0.27090894 |
128 | MAP2K2 | 0.26819491 |
129 | PDGFRA | 0.26105193 |
130 | PAK3 | 0.26102111 |
131 | PIK3CA | 0.25939955 |
132 | PBK | 0.25309891 |
133 | EPHA4 | 0.25303160 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 4.48225286 |
2 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 3.53775046 |
3 | Nitrogen metabolism_Homo sapiens_hsa00910 | 3.52751064 |
4 | Arginine biosynthesis_Homo sapiens_hsa00220 | 3.19828602 |
5 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 3.19694692 |
6 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 2.94561793 |
7 | Tryptophan metabolism_Homo sapiens_hsa00380 | 2.63727787 |
8 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 2.55484199 |
9 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 2.54751330 |
10 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 2.50787023 |
11 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.42812528 |
12 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.32605535 |
13 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 2.15618587 |
14 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 2.13563895 |
15 | Peroxisome_Homo sapiens_hsa04146 | 2.07767197 |
16 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.99485696 |
17 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.96276691 |
18 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.95626092 |
19 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.95022317 |
20 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.92254785 |
21 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.92234184 |
22 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.91678426 |
23 | Histidine metabolism_Homo sapiens_hsa00340 | 1.88084221 |
24 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.85160115 |
25 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.79276760 |
26 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.73308148 |
27 | Retinol metabolism_Homo sapiens_hsa00830 | 1.69763515 |
28 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.69648305 |
29 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.67649850 |
30 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.65567867 |
31 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.59988399 |
32 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.59072624 |
33 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.54992219 |
34 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.52612394 |
35 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.49194813 |
36 | Bile secretion_Homo sapiens_hsa04976 | 1.42494101 |
37 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.38535496 |
38 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.35506348 |
39 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.34747235 |
40 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.30304630 |
41 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.28976984 |
42 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.25395244 |
43 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.25036096 |
44 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.24917870 |
45 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.23300062 |
46 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.22767795 |
47 | ABC transporters_Homo sapiens_hsa02010 | 1.18375497 |
48 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.16557450 |
49 | Carbon metabolism_Homo sapiens_hsa01200 | 1.14062219 |
50 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.06652724 |
51 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.96528358 |
52 | Sulfur relay system_Homo sapiens_hsa04122 | 0.94177481 |
53 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.92624088 |
54 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.92346439 |
55 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.88615296 |
56 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.87598916 |
57 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.87154743 |
58 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.82329162 |
59 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.76222303 |
60 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.72604702 |
61 | Lysine degradation_Homo sapiens_hsa00310 | 0.72590347 |
62 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.70725293 |
63 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.69973456 |
64 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.66221534 |
65 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.64635264 |
66 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.49909669 |
67 | Metabolic pathways_Homo sapiens_hsa01100 | 0.45732871 |
68 | Prion diseases_Homo sapiens_hsa05020 | 0.42708572 |
69 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.38685330 |
70 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.32844360 |
71 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.28523928 |
72 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.28467824 |
73 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.28130649 |
74 | Insulin resistance_Homo sapiens_hsa04931 | 0.25193504 |
75 | Galactose metabolism_Homo sapiens_hsa00052 | 0.24253475 |
76 | Other glycan degradation_Homo sapiens_hsa00511 | 0.21155753 |
77 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.20908227 |
78 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.18862172 |
79 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.10312047 |
80 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.06475392 |
81 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | -0.2260555 |
82 | Bladder cancer_Homo sapiens_hsa05219 | -0.2075640 |
83 | Renin-angiotensin system_Homo sapiens_hsa04614 | -0.2065534 |
84 | Ether lipid metabolism_Homo sapiens_hsa00565 | -0.2022370 |
85 | Type II diabetes mellitus_Homo sapiens_hsa04930 | -0.2020136 |
86 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | -0.2019838 |
87 | Circadian rhythm_Homo sapiens_hsa04710 | -0.2015698 |
88 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | -0.2000292 |
89 | Amoebiasis_Homo sapiens_hsa05146 | -0.1955680 |
90 | Pertussis_Homo sapiens_hsa05133 | -0.1901545 |
91 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | -0.1817082 |
92 | Sphingolipid metabolism_Homo sapiens_hsa00600 | -0.1774050 |
93 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | -0.1540105 |
94 | Regulation of autophagy_Homo sapiens_hsa04140 | -0.1535493 |
95 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | -0.1522395 |
96 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | -0.1511982 |
97 | African trypanosomiasis_Homo sapiens_hsa05143 | -0.1424513 |
98 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | -0.1364871 |
99 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | -0.1299899 |
100 | Hepatitis C_Homo sapiens_hsa05160 | -0.1234327 |
101 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | -0.0994712 |
102 | Insulin signaling pathway_Homo sapiens_hsa04910 | -0.0857300 |
103 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | -0.0819032 |
104 | Serotonergic synapse_Homo sapiens_hsa04726 | -0.0787496 |
105 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | -0.0769140 |
106 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | -0.0377579 |
107 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | -0.0166329 |
108 | Mineral absorption_Homo sapiens_hsa04978 | -0.0095348 |