Rank | Gene Set | Z-score |
---|---|---|
1 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 6.48722844 |
2 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.76186146 |
3 | ATP synthesis coupled proton transport (GO:0015986) | 5.76186146 |
4 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 5.75168398 |
5 | chaperone-mediated protein transport (GO:0072321) | 5.46567474 |
6 | respiratory electron transport chain (GO:0022904) | 5.31522834 |
7 | electron transport chain (GO:0022900) | 5.24956801 |
8 | ribosomal small subunit assembly (GO:0000028) | 5.07468201 |
9 | protein complex biogenesis (GO:0070271) | 4.97765528 |
10 | proteasome assembly (GO:0043248) | 4.77442001 |
11 | DNA deamination (GO:0045006) | 4.74599653 |
12 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.67408833 |
13 | protein neddylation (GO:0045116) | 4.45368261 |
14 | ribosomal small subunit biogenesis (GO:0042274) | 4.42781569 |
15 | viral transcription (GO:0019083) | 4.37745251 |
16 | translational termination (GO:0006415) | 4.26490816 |
17 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.15389861 |
18 | maturation of SSU-rRNA (GO:0030490) | 4.09778171 |
19 | cotranslational protein targeting to membrane (GO:0006613) | 4.09447623 |
20 | protein targeting to ER (GO:0045047) | 4.05770946 |
21 | ribosomal large subunit biogenesis (GO:0042273) | 4.00569856 |
22 | protein localization to endoplasmic reticulum (GO:0070972) | 3.90789895 |
23 | protein targeting to mitochondrion (GO:0006626) | 3.86591572 |
24 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.83495814 |
25 | hydrogen ion transmembrane transport (GO:1902600) | 3.70044201 |
26 | translational elongation (GO:0006414) | 3.66432238 |
27 | establishment of protein localization to mitochondrion (GO:0072655) | 3.66080222 |
28 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.63784978 |
29 | rRNA methylation (GO:0031167) | 3.62573273 |
30 | protein localization to mitochondrion (GO:0070585) | 3.51888257 |
31 | cullin deneddylation (GO:0010388) | 3.49974534 |
32 | termination of RNA polymerase III transcription (GO:0006386) | 3.48224911 |
33 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.48224911 |
34 | protein deneddylation (GO:0000338) | 3.43462397 |
35 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.41905565 |
36 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.40237281 |
37 | proton transport (GO:0015992) | 3.39215806 |
38 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.36490916 |
39 | translational initiation (GO:0006413) | 3.35959235 |
40 | viral life cycle (GO:0019058) | 3.35257848 |
41 | mannosylation (GO:0097502) | 3.34833719 |
42 | translation (GO:0006412) | 3.32046976 |
43 | hydrogen transport (GO:0006818) | 3.31389369 |
44 | intracellular protein transmembrane import (GO:0044743) | 3.31189216 |
45 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.30284897 |
46 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.27646281 |
47 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.27563057 |
48 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.24753903 |
49 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.19168310 |
50 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.19168310 |
51 | cellular protein complex disassembly (GO:0043624) | 3.19019655 |
52 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.18885387 |
53 | ATP biosynthetic process (GO:0006754) | 3.17265895 |
54 | protein-cofactor linkage (GO:0018065) | 3.16803692 |
55 | inner mitochondrial membrane organization (GO:0007007) | 3.15134316 |
56 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.14134847 |
57 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.13750567 |
58 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.13336046 |
59 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.09636007 |
60 | platelet dense granule organization (GO:0060155) | 3.07849382 |
61 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.06252879 |
62 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.06252879 |
63 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.05581427 |
64 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.05581427 |
65 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.05581427 |
66 | cytidine metabolic process (GO:0046087) | 3.05357296 |
67 | cytidine catabolic process (GO:0006216) | 3.05357296 |
68 | cytidine deamination (GO:0009972) | 3.05357296 |
69 | mitochondrial transport (GO:0006839) | 3.00545759 |
70 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.00203607 |
71 | negative regulation of ligase activity (GO:0051352) | 2.98512005 |
72 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.98512005 |
73 | telomere maintenance via recombination (GO:0000722) | 2.97992177 |
74 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.96640658 |
75 | DNA strand elongation (GO:0022616) | 2.94964560 |
76 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.93297553 |
77 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.93297553 |
78 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.92324801 |
79 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.89620777 |
80 | formation of translation preinitiation complex (GO:0001731) | 2.89494212 |
81 | peptidyl-histidine modification (GO:0018202) | 2.88575680 |
82 | CENP-A containing nucleosome assembly (GO:0034080) | 2.87657771 |
83 | pseudouridine synthesis (GO:0001522) | 2.87351006 |
84 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.85412984 |
85 | dolichol-linked oligosaccharide biosynthetic process (GO:0006488) | 2.85334977 |
86 | cellular component biogenesis (GO:0044085) | 2.84614815 |
87 | rRNA modification (GO:0000154) | 2.84260311 |
88 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.82393686 |
89 | signal peptide processing (GO:0006465) | 2.80671980 |
90 | protein maturation by protein folding (GO:0022417) | 2.80521744 |
91 | respiratory chain complex IV assembly (GO:0008535) | 2.78543871 |
92 | 7-methylguanosine mRNA capping (GO:0006370) | 2.78418794 |
93 | purine nucleobase biosynthetic process (GO:0009113) | 2.77487671 |
94 | positive regulation of prostaglandin secretion (GO:0032308) | 2.77165312 |
95 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 2.77159891 |
96 | L-methionine salvage (GO:0071267) | 2.76939989 |
97 | L-methionine biosynthetic process (GO:0071265) | 2.76939989 |
98 | amino acid salvage (GO:0043102) | 2.76939989 |
99 | C-terminal protein lipidation (GO:0006501) | 2.75910714 |
100 | rRNA processing (GO:0006364) | 2.75846554 |
101 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.75715220 |
102 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.75583994 |
103 | 7-methylguanosine RNA capping (GO:0009452) | 2.74417418 |
104 | RNA capping (GO:0036260) | 2.74417418 |
105 | regulation of mitochondrial translation (GO:0070129) | 2.73622616 |
106 | regulation of ligase activity (GO:0051340) | 2.73075218 |
107 | chromatin remodeling at centromere (GO:0031055) | 2.72927260 |
108 | tRNA processing (GO:0008033) | 2.72246735 |
109 | positive regulation of cell cycle arrest (GO:0071158) | 2.71531487 |
110 | negative regulation of protein ubiquitination (GO:0031397) | 2.70881314 |
111 | DNA replication initiation (GO:0006270) | 2.69717018 |
112 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.69219703 |
113 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.68232001 |
114 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.66795691 |
115 | nucleobase biosynthetic process (GO:0046112) | 2.64267822 |
116 | transcription-coupled nucleotide-excision repair (GO:0006283) | 2.64128229 |
117 | protein complex disassembly (GO:0043241) | 2.64095712 |
118 | mitotic recombination (GO:0006312) | 2.63460786 |
119 | rRNA metabolic process (GO:0016072) | 2.63120960 |
120 | DNA replication checkpoint (GO:0000076) | 2.62618033 |
121 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 2.61045763 |
122 | protein targeting to membrane (GO:0006612) | 2.59834090 |
123 | cellular response to zinc ion (GO:0071294) | 2.59546266 |
124 | eosinophil chemotaxis (GO:0048245) | 2.59352313 |
125 | aldehyde catabolic process (GO:0046185) | 2.58743618 |
126 | ribosome biogenesis (GO:0042254) | 2.58661781 |
127 | pteridine-containing compound biosynthetic process (GO:0042559) | 2.57799732 |
128 | telomere maintenance via telomere lengthening (GO:0010833) | 2.57298262 |
129 | ribosome assembly (GO:0042255) | 2.56331587 |
130 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.55360097 |
131 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.53694175 |
132 | fatty acid elongation (GO:0030497) | 2.53029997 |
133 | macromolecular complex disassembly (GO:0032984) | 2.51826513 |
134 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.51405068 |
135 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.49588604 |
136 | cytochrome complex assembly (GO:0017004) | 2.49374767 |
137 | GTP biosynthetic process (GO:0006183) | 2.49053063 |
138 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.48676943 |
139 | positive regulation of ligase activity (GO:0051351) | 2.47016410 |
140 | spliceosomal snRNP assembly (GO:0000387) | 2.46457084 |
141 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.45040137 |
142 | NADH dehydrogenase complex assembly (GO:0010257) | 2.45040137 |
143 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.45040137 |
144 | response to interferon-beta (GO:0035456) | 2.45026379 |
145 | transcription from RNA polymerase I promoter (GO:0006360) | 2.42952586 |
146 | regulation of cellular amine metabolic process (GO:0033238) | 2.42678819 |
147 | metallo-sulfur cluster assembly (GO:0031163) | 2.42400881 |
148 | iron-sulfur cluster assembly (GO:0016226) | 2.42400881 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 4.56853098 |
2 | * KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.14145465 |
3 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.87254339 |
4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.66639957 |
5 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.58551829 |
6 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.37347742 |
7 | * JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.37259389 |
8 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.36681360 |
9 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.18435156 |
10 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.10672533 |
11 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.03066740 |
12 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 3.00094472 |
13 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.91911285 |
14 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.72071170 |
15 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.66096739 |
16 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.42982976 |
17 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.38901035 |
18 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.35572062 |
19 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.34140381 |
20 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.33235090 |
21 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.27882999 |
22 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.18568925 |
23 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.18193153 |
24 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.14189673 |
25 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.14010587 |
26 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.11773144 |
27 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.10227687 |
28 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.07781167 |
29 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.06653420 |
30 | * FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.05513449 |
31 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.95453444 |
32 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.91367675 |
33 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.90747329 |
34 | * XRN2_22483619_ChIP-Seq_HELA_Human | 1.87943189 |
35 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.84128552 |
36 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.82711894 |
37 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.81822507 |
38 | * CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.79683450 |
39 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.79641834 |
40 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.78355793 |
41 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.77391438 |
42 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.74348805 |
43 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.64763941 |
44 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.64300530 |
45 | * PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.63027131 |
46 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.62912215 |
47 | * CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.61195144 |
48 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.60964662 |
49 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.56174965 |
50 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.51694026 |
51 | * MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.48342454 |
52 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.47725891 |
53 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.42601206 |
54 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.40241413 |
55 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.38826311 |
56 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.37841530 |
57 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.33882669 |
58 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.31101513 |
59 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.29914132 |
60 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.25504060 |
61 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.24117873 |
62 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.23988813 |
63 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.21902094 |
64 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.20541538 |
65 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.20149610 |
66 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.18872189 |
67 | VDR_22108803_ChIP-Seq_LS180_Human | 1.17633329 |
68 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.17135841 |
69 | ELF5_23300383_ChIP-Seq_T47D_Human | 1.16534085 |
70 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.16043973 |
71 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.14284564 |
72 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.13127230 |
73 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.11841372 |
74 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.11839694 |
75 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.10644289 |
76 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.08678384 |
77 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.07395402 |
78 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.05775014 |
79 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.05074374 |
80 | AR_20517297_ChIP-Seq_VCAP_Human | 1.04935970 |
81 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.04621660 |
82 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.04479747 |
83 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.02486728 |
84 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.02418557 |
85 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.01948765 |
86 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.00734947 |
87 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.00510889 |
88 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.99115299 |
89 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.99115299 |
90 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 0.96835497 |
91 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.95511204 |
92 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.95068414 |
93 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.94633815 |
94 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 0.93175416 |
95 | GATA1_22025678_ChIP-Seq_K562_Human | 0.93038177 |
96 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 0.92113974 |
97 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.91940118 |
98 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.91771447 |
99 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 0.91681675 |
100 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.91670297 |
101 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.90886208 |
102 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.90260283 |
103 | * E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.88796282 |
104 | * PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.88090794 |
105 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.87695106 |
106 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.87647255 |
107 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 0.85869944 |
108 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.85284369 |
109 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.85051338 |
110 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.84958495 |
111 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.84829790 |
112 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.84780190 |
113 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 0.84290531 |
114 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.82790617 |
115 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.81987402 |
116 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 0.80688973 |
117 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.79537259 |
118 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.79338577 |
119 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.78014000 |
120 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.77728993 |
121 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 0.77276220 |
122 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.77005552 |
123 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.76554555 |
124 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.76142152 |
125 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.75225142 |
126 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.75153935 |
127 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.74672167 |
128 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.73471390 |
129 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.73447710 |
130 | EWS_26573619_Chip-Seq_HEK293_Human | 0.72100472 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0002163_abnormal_gland_morphology | 3.54673783 |
2 | MP0003806_abnormal_nucleotide_metabolis | 3.16441639 |
3 | MP0003693_abnormal_embryo_hatching | 3.10293548 |
4 | MP0005379_endocrine/exocrine_gland_phen | 2.93325949 |
5 | MP0003186_abnormal_redox_activity | 2.77993471 |
6 | MP0002837_dystrophic_cardiac_calcinosis | 2.74311931 |
7 | MP0005084_abnormal_gallbladder_morpholo | 2.61494170 |
8 | MP0009379_abnormal_foot_pigmentation | 2.55307339 |
9 | MP0008057_abnormal_DNA_replication | 2.53944405 |
10 | MP0001835_abnormal_antigen_presentation | 2.37331266 |
11 | MP0004381_abnormal_hair_follicle | 2.36748007 |
12 | MP0009785_altered_susceptibility_to | 2.29270778 |
13 | MP0002254_reproductive_system_inflammat | 2.23681064 |
14 | MP0008058_abnormal_DNA_repair | 2.17075933 |
15 | MP0003724_increased_susceptibility_to | 2.14129165 |
16 | MP0004957_abnormal_blastocyst_morpholog | 2.10383605 |
17 | MP0002148_abnormal_hypersensitivity_rea | 2.06875431 |
18 | MP0010094_abnormal_chromosome_stability | 1.94775494 |
19 | MP0010386_abnormal_urinary_bladder | 1.90246469 |
20 | MP0002396_abnormal_hematopoietic_system | 1.88590327 |
21 | MP0005671_abnormal_response_to | 1.87570215 |
22 | MP0005025_abnormal_response_to | 1.84387310 |
23 | MP0006072_abnormal_retinal_apoptosis | 1.81469533 |
24 | MP0002876_abnormal_thyroid_physiology | 1.79503951 |
25 | MP0008007_abnormal_cellular_replicative | 1.76278034 |
26 | MP0005451_abnormal_body_composition | 1.75496097 |
27 | MP0009333_abnormal_splenocyte_physiolog | 1.75411486 |
28 | MP0003718_maternal_effect | 1.74494610 |
29 | MP0003136_yellow_coat_color | 1.74099699 |
30 | MP0003111_abnormal_nucleus_morphology | 1.72984526 |
31 | MP0003077_abnormal_cell_cycle | 1.72137571 |
32 | MP0005075_abnormal_melanosome_morpholog | 1.70712477 |
33 | MP0005408_hypopigmentation | 1.69533254 |
34 | MP0002139_abnormal_hepatobiliary_system | 1.67904768 |
35 | MP0002132_abnormal_respiratory_system | 1.67039425 |
36 | MP0001853_heart_inflammation | 1.66188622 |
37 | MP0005000_abnormal_immune_tolerance | 1.64110246 |
38 | MP0003786_premature_aging | 1.61591669 |
39 | MP0003436_decreased_susceptibility_to | 1.58919422 |
40 | MP0006035_abnormal_mitochondrial_morpho | 1.58402511 |
41 | MP0003656_abnormal_erythrocyte_physiolo | 1.57501251 |
42 | MP0000685_abnormal_immune_system | 1.57022580 |
43 | MP0002419_abnormal_innate_immunity | 1.53732768 |
44 | MP0004147_increased_porphyrin_level | 1.52166771 |
45 | MP0005360_urolithiasis | 1.50214414 |
46 | MP0002693_abnormal_pancreas_physiology | 1.48860095 |
47 | MP0005645_abnormal_hypothalamus_physiol | 1.45885914 |
48 | MP0002723_abnormal_immune_serum | 1.45628472 |
49 | MP0003195_calcinosis | 1.42480951 |
50 | MP0003763_abnormal_thymus_physiology | 1.42241802 |
51 | MP0001800_abnormal_humoral_immune | 1.40199854 |
52 | MP0002452_abnormal_antigen_presenting | 1.39757220 |
53 | MP0008932_abnormal_embryonic_tissue | 1.38864258 |
54 | MP0001919_abnormal_reproductive_system | 1.34629379 |
55 | MP0001764_abnormal_homeostasis | 1.34341930 |
56 | MP0003123_paternal_imprinting | 1.33104211 |
57 | MP0002653_abnormal_ependyma_morphology | 1.32489813 |
58 | MP0004782_abnormal_surfactant_physiolog | 1.32310922 |
59 | MP0002420_abnormal_adaptive_immunity | 1.31356267 |
60 | MP0001819_abnormal_immune_cell | 1.30427034 |
61 | MP0008469_abnormal_protein_level | 1.26099382 |
62 | MP0002796_impaired_skin_barrier | 1.25894833 |
63 | MP0001905_abnormal_dopamine_level | 1.25653326 |
64 | MP0005085_abnormal_gallbladder_physiolo | 1.25130562 |
65 | MP0000490_abnormal_crypts_of | 1.24772038 |
66 | MP0009764_decreased_sensitivity_to | 1.22507791 |
67 | MP0008875_abnormal_xenobiotic_pharmacok | 1.19308464 |
68 | MP0005310_abnormal_salivary_gland | 1.18820695 |
69 | MP0001845_abnormal_inflammatory_respons | 1.15943553 |
70 | MP0005387_immune_system_phenotype | 1.15749717 |
71 | MP0001790_abnormal_immune_system | 1.15749717 |
72 | MP0002405_respiratory_system_inflammati | 1.15196900 |
73 | MP0000689_abnormal_spleen_morphology | 1.14987257 |
74 | MP0002277_abnormal_respiratory_mucosa | 1.14418026 |
75 | MP0001756_abnormal_urination | 1.14213069 |
76 | MP0000858_altered_metastatic_potential | 1.14000431 |
77 | MP0005389_reproductive_system_phenotype | 1.12379249 |
78 | MP0010155_abnormal_intestine_physiology | 1.11723787 |
79 | MP0000716_abnormal_immune_system | 1.11023501 |
80 | MP0009697_abnormal_copulation | 1.11015504 |
81 | MP0002398_abnormal_bone_marrow | 1.10921208 |
82 | MP0008877_abnormal_DNA_methylation | 1.10765074 |
83 | MP0006082_CNS_inflammation | 1.09617357 |
84 | MP0002722_abnormal_immune_system | 1.09164313 |
85 | MP0003941_abnormal_skin_development | 1.09038787 |
86 | MP0003315_abnormal_perineum_morphology | 1.09034186 |
87 | MP0006036_abnormal_mitochondrial_physio | 1.08361193 |
88 | MP0001944_abnormal_pancreas_morphology | 1.07795464 |
89 | MP0008872_abnormal_physiological_respon | 1.06867332 |
90 | MP0005319_abnormal_enzyme/_coenzyme | 1.06518787 |
91 | MP0002429_abnormal_blood_cell | 1.05634063 |
92 | MP0002006_tumorigenesis | 1.05493614 |
93 | MP0000358_abnormal_cell_content/ | 1.03889287 |
94 | MP0008260_abnormal_autophagy | 1.03432915 |
95 | MP0005501_abnormal_skin_physiology | 1.02290095 |
96 | MP0002098_abnormal_vibrissa_morphology | 1.01525460 |
97 | MP0003866_abnormal_defecation | 1.01108325 |
98 | MP0005083_abnormal_biliary_tract | 1.00932635 |
99 | MP0005464_abnormal_platelet_physiology | 1.00723084 |
100 | MP0001542_abnormal_bone_strength | 0.97522063 |
101 | MP0000383_abnormal_hair_follicle | 0.97059359 |
102 | MP0000372_irregular_coat_pigmentation | 0.95909609 |
103 | MP0001666_abnormal_nutrient_absorption | 0.95839620 |
104 | MP0010234_abnormal_vibrissa_follicle | 0.95577025 |
105 | MP0004019_abnormal_vitamin_homeostasis | 0.95050612 |
106 | MP0005397_hematopoietic_system_phenotyp | 0.94992256 |
107 | MP0001545_abnormal_hematopoietic_system | 0.94992256 |
108 | MP0006054_spinal_hemorrhage | 0.94876017 |
109 | MP0003011_delayed_dark_adaptation | 0.94685338 |
110 | MP0009840_abnormal_foam_cell | 0.94273209 |
111 | MP0002166_altered_tumor_susceptibility | 0.93731749 |
112 | MP0005636_abnormal_mineral_homeostasis | 0.92904967 |
113 | MP0004947_skin_inflammation | 0.91465355 |
114 | MP0008789_abnormal_olfactory_epithelium | 0.91206625 |
115 | MP0003787_abnormal_imprinting | 0.91138337 |
116 | MP0002019_abnormal_tumor_incidence | 0.89654083 |
117 | MP0009643_abnormal_urine_homeostasis | 0.89414242 |
118 | MP0005551_abnormal_eye_electrophysiolog | 0.89199501 |
119 | MP0001873_stomach_inflammation | 0.88847221 |
120 | MP0005058_abnormal_lysosome_morphology | 0.88151502 |
121 | MP0002090_abnormal_vision | 0.87166717 |
122 | MP0000427_abnormal_hair_cycle | 0.86913419 |
123 | MP0002138_abnormal_hepatobiliary_system | 0.86406899 |
124 | MP0005365_abnormal_bile_salt | 0.86349159 |
125 | MP0002938_white_spotting | 0.85974382 |
126 | MP0005410_abnormal_fertilization | 0.84854917 |
127 | MP0002909_abnormal_adrenal_gland | 0.84116587 |
128 | MP0009765_abnormal_xenobiotic_induced | 0.83429695 |
129 | MP0001881_abnormal_mammary_gland | 0.83341992 |
130 | MP0000647_abnormal_sebaceous_gland | 0.83197558 |
131 | MP0005253_abnormal_eye_physiology | 0.82785141 |
132 | MP0000538_abnormal_urinary_bladder | 0.81775979 |
133 | MP0001529_abnormal_vocalization | 0.81534758 |
134 | MP0002095_abnormal_skin_pigmentation | 0.81406352 |
135 | MP0005332_abnormal_amino_acid | 0.80991369 |
136 | MP0006292_abnormal_olfactory_placode | 0.80677750 |
137 | MP0001986_abnormal_taste_sensitivity | 0.80551901 |
138 | MP0002736_abnormal_nociception_after | 0.80338424 |
139 | MP0001216_abnormal_epidermal_layer | 0.80301523 |
140 | MP0009763_increased_sensitivity_to | 0.80029123 |
141 | MP0001765_abnormal_ion_homeostasis | 0.78220136 |
142 | MP0000465_gastrointestinal_hemorrhage | 0.74409680 |
143 | MP0000566_synostosis | 0.74346875 |
144 | MP0000313_abnormal_cell_death | 0.74245456 |
145 | MP0001727_abnormal_embryo_implantation | 0.72497253 |
146 | MP0002160_abnormal_reproductive_system | 0.71768798 |
147 | MP0003950_abnormal_plasma_membrane | 0.70479950 |
148 | MP0008995_early_reproductive_senescence | 0.70332174 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.40195208 |
2 | Abnormal number of erythroid precursors (HP:0012131) | 4.38456508 |
3 | Reticulocytopenia (HP:0001896) | 3.64442576 |
4 | 3-Methylglutaconic aciduria (HP:0003535) | 3.50747309 |
5 | Macrocytic anemia (HP:0001972) | 3.23798063 |
6 | Parakeratosis (HP:0001036) | 3.15511545 |
7 | Increased hepatocellular lipid droplets (HP:0006565) | 3.00442414 |
8 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.92124287 |
9 | Hepatocellular necrosis (HP:0001404) | 2.91885000 |
10 | Lipid accumulation in hepatocytes (HP:0006561) | 2.90693901 |
11 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.89387201 |
12 | Mitochondrial inheritance (HP:0001427) | 2.88755507 |
13 | Hepatic necrosis (HP:0002605) | 2.88613617 |
14 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.78591633 |
15 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.78591633 |
16 | Type I transferrin isoform profile (HP:0003642) | 2.76479942 |
17 | Oral leukoplakia (HP:0002745) | 2.76110548 |
18 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.75569180 |
19 | Renal Fanconi syndrome (HP:0001994) | 2.74856183 |
20 | Acute necrotizing encephalopathy (HP:0006965) | 2.71418423 |
21 | Pallor (HP:0000980) | 2.71399008 |
22 | Reduced antithrombin III activity (HP:0001976) | 2.68467843 |
23 | Pancreatic cysts (HP:0001737) | 2.68436652 |
24 | Optic disc pallor (HP:0000543) | 2.67421454 |
25 | Aplastic anemia (HP:0001915) | 2.65650765 |
26 | Congenital ichthyosiform erythroderma (HP:0007431) | 2.64785839 |
27 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.63459529 |
28 | Increased CSF lactate (HP:0002490) | 2.62963131 |
29 | Recurrent abscess formation (HP:0002722) | 2.61763851 |
30 | Acute encephalopathy (HP:0006846) | 2.56833726 |
31 | Abnormality of midbrain morphology (HP:0002418) | 2.56740360 |
32 | Molar tooth sign on MRI (HP:0002419) | 2.56740360 |
33 | Increased serum lactate (HP:0002151) | 2.50933943 |
34 | Exertional dyspnea (HP:0002875) | 2.50928426 |
35 | Congenital, generalized hypertrichosis (HP:0004540) | 2.48462265 |
36 | Pancreatic fibrosis (HP:0100732) | 2.47491916 |
37 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.46672912 |
38 | Methylmalonic aciduria (HP:0012120) | 2.45542290 |
39 | Petechiae (HP:0000967) | 2.45249072 |
40 | Recurrent bacterial skin infections (HP:0005406) | 2.43779498 |
41 | Birth length less than 3rd percentile (HP:0003561) | 2.42635381 |
42 | Poor head control (HP:0002421) | 2.41130197 |
43 | Sparse eyelashes (HP:0000653) | 2.36886839 |
44 | Vacuolated lymphocytes (HP:0001922) | 2.36359211 |
45 | Leukodystrophy (HP:0002415) | 2.36235063 |
46 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.36186037 |
47 | Rough bone trabeculation (HP:0100670) | 2.35400082 |
48 | True hermaphroditism (HP:0010459) | 2.28655072 |
49 | Pancytopenia (HP:0001876) | 2.28559234 |
50 | IgM deficiency (HP:0002850) | 2.23931681 |
51 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 2.19518120 |
52 | Methylmalonic acidemia (HP:0002912) | 2.19215939 |
53 | Hepatosplenomegaly (HP:0001433) | 2.18806631 |
54 | Increased intramyocellular lipid droplets (HP:0012240) | 2.16657620 |
55 | Abnormal hemoglobin (HP:0011902) | 2.16453380 |
56 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 2.15292113 |
57 | Breast hypoplasia (HP:0003187) | 2.15117240 |
58 | Prolonged neonatal jaundice (HP:0006579) | 2.14918504 |
59 | Cerebral hypomyelination (HP:0006808) | 2.12091318 |
60 | Hyperphosphaturia (HP:0003109) | 2.11704161 |
61 | Microretrognathia (HP:0000308) | 2.09454650 |
62 | Hypothermia (HP:0002045) | 2.08680347 |
63 | Abnormality of macrophages (HP:0004311) | 2.07536096 |
64 | Abnormal protein glycosylation (HP:0012346) | 2.07332597 |
65 | Abnormal glycosylation (HP:0012345) | 2.07332597 |
66 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.07332597 |
67 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.07332597 |
68 | Abnormality of the axillary hair (HP:0100134) | 2.03971066 |
69 | Abnormality of secondary sexual hair (HP:0009888) | 2.03971066 |
70 | CNS demyelination (HP:0007305) | 2.02856885 |
71 | Progressive macrocephaly (HP:0004481) | 2.02803061 |
72 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.01588320 |
73 | Respiratory difficulties (HP:0002880) | 2.01360798 |
74 | X-linked dominant inheritance (HP:0001423) | 2.01152744 |
75 | Eczematoid dermatitis (HP:0000976) | 1.99193196 |
76 | Increased muscle lipid content (HP:0009058) | 1.97361238 |
77 | Lactic acidosis (HP:0003128) | 1.97125153 |
78 | Glycosuria (HP:0003076) | 1.96065142 |
79 | Abnormality of urine glucose concentration (HP:0011016) | 1.96065142 |
80 | Abnormal trabecular bone morphology (HP:0100671) | 1.95738449 |
81 | Carpal bone hypoplasia (HP:0001498) | 1.95511086 |
82 | Testicular atrophy (HP:0000029) | 1.95047881 |
83 | Pustule (HP:0200039) | 1.94973928 |
84 | Hypokinesia (HP:0002375) | 1.94679639 |
85 | Cerebral edema (HP:0002181) | 1.94351667 |
86 | Thrombocytosis (HP:0001894) | 1.93817313 |
87 | Abnormality of renal resorption (HP:0011038) | 1.93645225 |
88 | Prolonged partial thromboplastin time (HP:0003645) | 1.93078292 |
89 | Ketoacidosis (HP:0001993) | 1.92896660 |
90 | Hypoplasia of the uterus (HP:0000013) | 1.92012590 |
91 | Microvesicular hepatic steatosis (HP:0001414) | 1.90188991 |
92 | Generalized aminoaciduria (HP:0002909) | 1.89914145 |
93 | Abnormality of placental membranes (HP:0011409) | 1.88758141 |
94 | Amniotic constriction ring (HP:0009775) | 1.88758141 |
95 | Steatorrhea (HP:0002570) | 1.88562805 |
96 | Abnormality of T cell physiology (HP:0011840) | 1.88053928 |
97 | Intrahepatic cholestasis (HP:0001406) | 1.87644982 |
98 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.87481858 |
99 | Abnormality of alanine metabolism (HP:0010916) | 1.87481858 |
100 | Hyperalaninemia (HP:0003348) | 1.87481858 |
101 | Nausea (HP:0002018) | 1.86516253 |
102 | Autoimmune hemolytic anemia (HP:0001890) | 1.84940077 |
103 | Respiratory failure (HP:0002878) | 1.84659761 |
104 | IgG deficiency (HP:0004315) | 1.82735810 |
105 | Medial flaring of the eyebrow (HP:0010747) | 1.82652632 |
106 | Exercise intolerance (HP:0003546) | 1.82135587 |
107 | Neutropenia (HP:0001875) | 1.81069500 |
108 | Premature graying of hair (HP:0002216) | 1.80403278 |
109 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 1.79922544 |
110 | Obstructive lung disease (HP:0006536) | 1.79145675 |
111 | Chronic obstructive pulmonary disease (HP:0006510) | 1.79145675 |
112 | Blindness (HP:0000618) | 1.77928561 |
113 | Abnormality of liposaccharide metabolism (HP:0010968) | 1.77764346 |
114 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 1.77764346 |
115 | Abnormality of glycolipid metabolism (HP:0010969) | 1.77764346 |
116 | Abnormality of glycolysis (HP:0004366) | 1.77415466 |
117 | Increased serum pyruvate (HP:0003542) | 1.77415466 |
118 | Lymphoma (HP:0002665) | 1.76583724 |
119 | Erythroderma (HP:0001019) | 1.76284866 |
120 | Lethargy (HP:0001254) | 1.75532046 |
121 | Stomatitis (HP:0010280) | 1.75402562 |
122 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.75362259 |
123 | Abnormality of the anterior horn cell (HP:0006802) | 1.75305698 |
124 | Degeneration of anterior horn cells (HP:0002398) | 1.75305698 |
125 | Recurrent skin infections (HP:0001581) | 1.74506837 |
126 | Hyperinsulinemic hypoglycemia (HP:0000825) | 1.73850580 |
127 | Abnormality of methionine metabolism (HP:0010901) | 1.73716265 |
128 | Hyperglycinemia (HP:0002154) | 1.73317817 |
129 | Megaloblastic anemia (HP:0001889) | 1.73192143 |
130 | Abnormality of pyrimidine metabolism (HP:0004353) | 1.72370144 |
131 | Sclerocornea (HP:0000647) | 1.72195704 |
132 | Severe combined immunodeficiency (HP:0004430) | 1.72101910 |
133 | Increased IgM level (HP:0003496) | 1.71202446 |
134 | 11 pairs of ribs (HP:0000878) | 1.70344843 |
135 | Combined immunodeficiency (HP:0005387) | 1.70028238 |
136 | Large for gestational age (HP:0001520) | 1.69420151 |
137 | Renal tubular dysfunction (HP:0000124) | 1.67363121 |
138 | Severe visual impairment (HP:0001141) | 1.67326312 |
139 | Vomiting (HP:0002013) | 1.66656376 |
140 | Palpitations (HP:0001962) | 1.66580467 |
141 | Hypoglycemic coma (HP:0001325) | 1.66560445 |
142 | Nephronophthisis (HP:0000090) | 1.65773220 |
143 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.64316376 |
144 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.63515904 |
145 | Ketosis (HP:0001946) | 1.61724353 |
146 | Furrowed tongue (HP:0000221) | 1.61540519 |
147 | Dicarboxylic aciduria (HP:0003215) | 1.60648556 |
148 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.60648556 |
Rank | Gene Set | Z-score |
---|---|---|
1 | VRK2 | 4.30357803 |
2 | STK16 | 3.71582517 |
3 | EIF2AK1 | 3.47148127 |
4 | PBK | 3.25082302 |
5 | NME2 | 3.20420749 |
6 | BUB1 | 3.09838053 |
7 | EIF2AK3 | 2.95867110 |
8 | WEE1 | 2.85382374 |
9 | MST4 | 2.39192827 |
10 | BLK | 2.21592427 |
11 | IRAK3 | 2.20341666 |
12 | VRK1 | 2.10692187 |
13 | NUAK1 | 2.10330940 |
14 | PIM2 | 2.06432441 |
15 | IRAK4 | 2.03059313 |
16 | TLK1 | 1.98558245 |
17 | TRIM28 | 1.87006363 |
18 | SRPK1 | 1.84130749 |
19 | TESK2 | 1.71744330 |
20 | FRK | 1.70650280 |
21 | MAP3K14 | 1.66478597 |
22 | KDR | 1.61262616 |
23 | MAP4K2 | 1.57682646 |
24 | ACVR1B | 1.54443046 |
25 | BRSK2 | 1.53114170 |
26 | INSRR | 1.48716506 |
27 | MAP4K1 | 1.48007731 |
28 | BCKDK | 1.45054607 |
29 | PLK4 | 1.43602298 |
30 | EPHA2 | 1.41402749 |
31 | EIF2AK2 | 1.40512343 |
32 | TXK | 1.38619193 |
33 | LIMK1 | 1.38133880 |
34 | PDK2 | 1.37315933 |
35 | TAF1 | 1.34147086 |
36 | TEC | 1.21985865 |
37 | IKBKE | 1.21606068 |
38 | IKBKB | 1.19868449 |
39 | DYRK3 | 1.17423715 |
40 | MKNK1 | 1.15730011 |
41 | TBK1 | 1.13244518 |
42 | ZAK | 1.13026114 |
43 | ZAP70 | 1.10193022 |
44 | MYLK | 1.10141880 |
45 | GRK7 | 1.08861832 |
46 | RPS6KB2 | 1.06420876 |
47 | CDC7 | 1.04324543 |
48 | PRKCI | 1.01477846 |
49 | WNK4 | 1.00958257 |
50 | MUSK | 0.98596458 |
51 | CSNK1G1 | 0.98584303 |
52 | ABL2 | 0.97109427 |
53 | STK39 | 0.96442969 |
54 | ARAF | 0.93207178 |
55 | WNK3 | 0.92912314 |
56 | BMPR1B | 0.91325906 |
57 | MAPKAPK5 | 0.89883053 |
58 | PAK4 | 0.89374026 |
59 | NEK1 | 0.88366427 |
60 | STK4 | 0.87610362 |
61 | ILK | 0.86673670 |
62 | YES1 | 0.86030462 |
63 | CDK7 | 0.84471496 |
64 | AURKB | 0.83609672 |
65 | TNIK | 0.82783583 |
66 | BCR | 0.80898429 |
67 | MAP3K3 | 0.80525009 |
68 | TYK2 | 0.80189410 |
69 | CSNK1G2 | 0.78931241 |
70 | PIM1 | 0.78856922 |
71 | DAPK1 | 0.78498985 |
72 | NME1 | 0.78112943 |
73 | RPS6KA4 | 0.77149545 |
74 | DYRK2 | 0.77109128 |
75 | TTK | 0.77096443 |
76 | BTK | 0.76959021 |
77 | PLK1 | 0.76152461 |
78 | CDK19 | 0.74406562 |
79 | MST1R | 0.74260874 |
80 | GRK1 | 0.73960164 |
81 | TSSK6 | 0.73563866 |
82 | AURKA | 0.73080947 |
83 | TAOK3 | 0.71903233 |
84 | MET | 0.71236041 |
85 | TESK1 | 0.70221308 |
86 | LYN | 0.69808855 |
87 | CLK1 | 0.68715647 |
88 | MKNK2 | 0.68109562 |
89 | RPS6KA5 | 0.67666030 |
90 | STK10 | 0.67551480 |
91 | CSNK1A1L | 0.67149293 |
92 | NLK | 0.65376039 |
93 | MAP3K11 | 0.64650283 |
94 | PINK1 | 0.64572936 |
95 | MAPKAPK3 | 0.64252071 |
96 | KIT | 0.63196746 |
97 | BRAF | 0.62479515 |
98 | CSNK2A1 | 0.58157848 |
99 | MAP3K8 | 0.58065296 |
100 | PRKCE | 0.57857432 |
101 | IRAK1 | 0.57285157 |
102 | LRRK2 | 0.57103916 |
103 | MAP2K2 | 0.56773478 |
104 | STK24 | 0.56325535 |
105 | MAP2K6 | 0.56066640 |
106 | NEK9 | 0.54745295 |
107 | ATR | 0.54580096 |
108 | BMPR2 | 0.53244378 |
109 | JAK3 | 0.53188028 |
110 | MAP3K12 | 0.52514388 |
111 | IRAK2 | 0.51367195 |
112 | ADRBK2 | 0.51052042 |
113 | DAPK3 | 0.50739363 |
114 | FER | 0.50359293 |
115 | SYK | 0.49771348 |
116 | ADRBK1 | 0.49767685 |
117 | CSNK1G3 | 0.48632215 |
118 | TIE1 | 0.48522062 |
119 | CSNK2A2 | 0.48515506 |
120 | CDK8 | 0.48441780 |
121 | NEK2 | 0.47664454 |
122 | OXSR1 | 0.47491196 |
123 | PAK3 | 0.47172919 |
124 | PRKCQ | 0.47012609 |
125 | ERN1 | 0.46982480 |
126 | STK38L | 0.46925305 |
127 | BRSK1 | 0.45927111 |
128 | SCYL2 | 0.44979461 |
129 | CSF1R | 0.43198266 |
130 | TRPM7 | 0.42843227 |
131 | MAP2K3 | 0.42575969 |
132 | MAP2K7 | 0.41857076 |
133 | LMTK2 | 0.40530782 |
134 | LCK | 0.40415145 |
135 | FLT3 | 0.39323909 |
136 | PLK3 | 0.38644205 |
137 | GRK5 | 0.37403382 |
138 | PHKG1 | 0.37287528 |
139 | PHKG2 | 0.37287528 |
140 | STK3 | 0.36636447 |
141 | MATK | 0.36578410 |
142 | PAK1 | 0.34655568 |
143 | CAMK2D | 0.32466926 |
144 | CSNK1A1 | 0.32132802 |
145 | TGFBR2 | 0.32030112 |
146 | ERBB3 | 0.31827091 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ribosome_Homo sapiens_hsa03010 | 4.00274548 |
2 | Proteasome_Homo sapiens_hsa03050 | 3.75283206 |
3 | DNA replication_Homo sapiens_hsa03030 | 2.94155248 |
4 | RNA polymerase_Homo sapiens_hsa03020 | 2.91043800 |
5 | Protein export_Homo sapiens_hsa03060 | 2.64901554 |
6 | Mismatch repair_Homo sapiens_hsa03430 | 2.30212962 |
7 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.19513442 |
8 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.18149130 |
9 | Homologous recombination_Homo sapiens_hsa03440 | 2.08744275 |
10 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.08426261 |
11 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.86218642 |
12 | Base excision repair_Homo sapiens_hsa03410 | 1.86155833 |
13 | Spliceosome_Homo sapiens_hsa03040 | 1.76535680 |
14 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.67898261 |
15 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.59490294 |
16 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.58929650 |
17 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.56752550 |
18 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.56199887 |
19 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.52944337 |
20 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.47762757 |
21 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.38365946 |
22 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.38314415 |
23 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.38229279 |
24 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.37827282 |
25 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.32764395 |
26 | Sulfur relay system_Homo sapiens_hsa04122 | 1.32523243 |
27 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.32376832 |
28 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.29459320 |
29 | Parkinsons disease_Homo sapiens_hsa05012 | 1.28696259 |
30 | Basal transcription factors_Homo sapiens_hsa03022 | 1.24834401 |
31 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.20389902 |
32 | RNA transport_Homo sapiens_hsa03013 | 1.19315844 |
33 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.16608795 |
34 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.12194379 |
35 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.12024985 |
36 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.11912118 |
37 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.11673197 |
38 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.08961088 |
39 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.07811561 |
40 | Purine metabolism_Homo sapiens_hsa00230 | 1.06383589 |
41 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.05317269 |
42 | Histidine metabolism_Homo sapiens_hsa00340 | 1.04438636 |
43 | Huntingtons disease_Homo sapiens_hsa05016 | 1.02346272 |
44 | RNA degradation_Homo sapiens_hsa03018 | 1.01910079 |
45 | Peroxisome_Homo sapiens_hsa04146 | 1.00054321 |
46 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.99666515 |
47 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.99370744 |
48 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.94161241 |
49 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.92260271 |
50 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.90909874 |
51 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.90506125 |
52 | Allograft rejection_Homo sapiens_hsa05330 | 0.89591312 |
53 | Retinol metabolism_Homo sapiens_hsa00830 | 0.88619362 |
54 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.88448897 |
55 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.87103453 |
56 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.86208819 |
57 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.85955310 |
58 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.84678895 |
59 | Cell cycle_Homo sapiens_hsa04110 | 0.84565936 |
60 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.84064616 |
61 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.83886601 |
62 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.83172188 |
63 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.82650435 |
64 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.81481367 |
65 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.81313935 |
66 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.80718782 |
67 | Legionellosis_Homo sapiens_hsa05134 | 0.80683975 |
68 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.78609794 |
69 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.78345177 |
70 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.76285870 |
71 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.76175952 |
72 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.76172645 |
73 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.76099018 |
74 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.75943824 |
75 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.75474856 |
76 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.75320436 |
77 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.75262960 |
78 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.74827320 |
79 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.73870621 |
80 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.72675371 |
81 | Alzheimers disease_Homo sapiens_hsa05010 | 0.72165176 |
82 | Metabolic pathways_Homo sapiens_hsa01100 | 0.71807026 |
83 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.71190571 |
84 | Mineral absorption_Homo sapiens_hsa04978 | 0.68626085 |
85 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.68588631 |
86 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.68527073 |
87 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.68483637 |
88 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.68264454 |
89 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.67876407 |
90 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.67323187 |
91 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.66761833 |
92 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.65601783 |
93 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.65533618 |
94 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.65473624 |
95 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.64547261 |
96 | Asthma_Homo sapiens_hsa05310 | 0.63237129 |
97 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.62476035 |
98 | Other glycan degradation_Homo sapiens_hsa00511 | 0.60463726 |
99 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.60344578 |
100 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.60047292 |
101 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.58290093 |
102 | Measles_Homo sapiens_hsa05162 | 0.57741864 |
103 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.57561665 |
104 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.57274892 |
105 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.57153145 |
106 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.57043859 |
107 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.56315339 |
108 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.54388107 |
109 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.53729624 |
110 | Lysosome_Homo sapiens_hsa04142 | 0.53238307 |
111 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.52864613 |
112 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.51548179 |
113 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.50911061 |
114 | Phototransduction_Homo sapiens_hsa04744 | 0.50521213 |
115 | Leishmaniasis_Homo sapiens_hsa05140 | 0.50132632 |
116 | Malaria_Homo sapiens_hsa05144 | 0.48245558 |
117 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.47984879 |
118 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.42808186 |
119 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.42355160 |
120 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.40555823 |
121 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.38283400 |
122 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.32428626 |
123 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.32372571 |