ORMDL2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1establishment of protein localization to mitochondrial membrane (GO:0090151)6.48722844
2energy coupled proton transport, down electrochemical gradient (GO:0015985)5.76186146
3ATP synthesis coupled proton transport (GO:0015986)5.76186146
4mitochondrial electron transport, NADH to ubiquinone (GO:0006120)5.75168398
5chaperone-mediated protein transport (GO:0072321)5.46567474
6respiratory electron transport chain (GO:0022904)5.31522834
7electron transport chain (GO:0022900)5.24956801
8ribosomal small subunit assembly (GO:0000028)5.07468201
9protein complex biogenesis (GO:0070271)4.97765528
10proteasome assembly (GO:0043248)4.77442001
11DNA deamination (GO:0045006)4.74599653
12mitochondrial respiratory chain complex assembly (GO:0033108)4.67408833
13protein neddylation (GO:0045116)4.45368261
14ribosomal small subunit biogenesis (GO:0042274)4.42781569
15viral transcription (GO:0019083)4.37745251
16translational termination (GO:0006415)4.26490816
17SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.15389861
18maturation of SSU-rRNA (GO:0030490)4.09778171
19cotranslational protein targeting to membrane (GO:0006613)4.09447623
20protein targeting to ER (GO:0045047)4.05770946
21ribosomal large subunit biogenesis (GO:0042273)4.00569856
22protein localization to endoplasmic reticulum (GO:0070972)3.90789895
23protein targeting to mitochondrion (GO:0006626)3.86591572
24establishment of protein localization to endoplasmic reticulum (GO:0072599)3.83495814
25hydrogen ion transmembrane transport (GO:1902600)3.70044201
26translational elongation (GO:0006414)3.66432238
27establishment of protein localization to mitochondrion (GO:0072655)3.66080222
28water-soluble vitamin biosynthetic process (GO:0042364)3.63784978
29rRNA methylation (GO:0031167)3.62573273
30protein localization to mitochondrion (GO:0070585)3.51888257
31cullin deneddylation (GO:0010388)3.49974534
32termination of RNA polymerase III transcription (GO:0006386)3.48224911
33transcription elongation from RNA polymerase III promoter (GO:0006385)3.48224911
34protein deneddylation (GO:0000338)3.43462397
35antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.41905565
36deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.40237281
37proton transport (GO:0015992)3.39215806
38telomere maintenance via semi-conservative replication (GO:0032201)3.36490916
39translational initiation (GO:0006413)3.35959235
40viral life cycle (GO:0019058)3.35257848
41mannosylation (GO:0097502)3.34833719
42translation (GO:0006412)3.32046976
43hydrogen transport (GO:0006818)3.31389369
44intracellular protein transmembrane import (GO:0044743)3.31189216
45antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.30284897
46regulation of cellular amino acid metabolic process (GO:0006521)3.27646281
47ribonucleoprotein complex biogenesis (GO:0022613)3.27563057
48negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.24753903
49RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.19168310
50tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.19168310
51cellular protein complex disassembly (GO:0043624)3.19019655
52purine nucleoside triphosphate biosynthetic process (GO:0009145)3.18885387
53ATP biosynthetic process (GO:0006754)3.17265895
54protein-cofactor linkage (GO:0018065)3.16803692
55inner mitochondrial membrane organization (GO:0007007)3.15134316
56nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.14134847
57purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.13750567
58DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.13336046
59DNA strand elongation involved in DNA replication (GO:0006271)3.09636007
60platelet dense granule organization (GO:0060155)3.07849382
61intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.06252879
62signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.06252879
63signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.05581427
64signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.05581427
65signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.05581427
66cytidine metabolic process (GO:0046087)3.05357296
67cytidine catabolic process (GO:0006216)3.05357296
68cytidine deamination (GO:0009972)3.05357296
69mitochondrial transport (GO:0006839)3.00545759
70positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.00203607
71negative regulation of ligase activity (GO:0051352)2.98512005
72negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.98512005
73telomere maintenance via recombination (GO:0000722)2.97992177
74regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.96640658
75DNA strand elongation (GO:0022616)2.94964560
76signal transduction involved in DNA damage checkpoint (GO:0072422)2.93297553
77signal transduction involved in DNA integrity checkpoint (GO:0072401)2.93297553
78L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.92324801
79signal transduction involved in cell cycle checkpoint (GO:0072395)2.89620777
80formation of translation preinitiation complex (GO:0001731)2.89494212
81peptidyl-histidine modification (GO:0018202)2.88575680
82CENP-A containing nucleosome assembly (GO:0034080)2.87657771
83pseudouridine synthesis (GO:0001522)2.87351006
84anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.85412984
85dolichol-linked oligosaccharide biosynthetic process (GO:0006488)2.85334977
86cellular component biogenesis (GO:0044085)2.84614815
87rRNA modification (GO:0000154)2.84260311
88regulation of ubiquitin-protein transferase activity (GO:0051438)2.82393686
89signal peptide processing (GO:0006465)2.80671980
90protein maturation by protein folding (GO:0022417)2.80521744
91respiratory chain complex IV assembly (GO:0008535)2.78543871
927-methylguanosine mRNA capping (GO:0006370)2.78418794
93purine nucleobase biosynthetic process (GO:0009113)2.77487671
94positive regulation of prostaglandin secretion (GO:0032308)2.77165312
95antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)2.77159891
96L-methionine salvage (GO:0071267)2.76939989
97L-methionine biosynthetic process (GO:0071265)2.76939989
98amino acid salvage (GO:0043102)2.76939989
99C-terminal protein lipidation (GO:0006501)2.75910714
100rRNA processing (GO:0006364)2.75846554
101regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.75715220
102ribonucleoside triphosphate biosynthetic process (GO:0009201)2.75583994
1037-methylguanosine RNA capping (GO:0009452)2.74417418
104RNA capping (GO:0036260)2.74417418
105regulation of mitochondrial translation (GO:0070129)2.73622616
106regulation of ligase activity (GO:0051340)2.73075218
107chromatin remodeling at centromere (GO:0031055)2.72927260
108tRNA processing (GO:0008033)2.72246735
109positive regulation of cell cycle arrest (GO:0071158)2.71531487
110negative regulation of protein ubiquitination (GO:0031397)2.70881314
111DNA replication initiation (GO:0006270)2.69717018
112exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.69219703
113nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.68232001
114preassembly of GPI anchor in ER membrane (GO:0016254)2.66795691
115nucleobase biosynthetic process (GO:0046112)2.64267822
116transcription-coupled nucleotide-excision repair (GO:0006283)2.64128229
117protein complex disassembly (GO:0043241)2.64095712
118mitotic recombination (GO:0006312)2.63460786
119rRNA metabolic process (GO:0016072)2.63120960
120DNA replication checkpoint (GO:0000076)2.62618033
121deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.61045763
122protein targeting to membrane (GO:0006612)2.59834090
123cellular response to zinc ion (GO:0071294)2.59546266
124eosinophil chemotaxis (GO:0048245)2.59352313
125aldehyde catabolic process (GO:0046185)2.58743618
126ribosome biogenesis (GO:0042254)2.58661781
127pteridine-containing compound biosynthetic process (GO:0042559)2.57799732
128telomere maintenance via telomere lengthening (GO:0010833)2.57298262
129ribosome assembly (GO:0042255)2.56331587
130pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.55360097
131mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.53694175
132fatty acid elongation (GO:0030497)2.53029997
133macromolecular complex disassembly (GO:0032984)2.51826513
134DNA damage response, signal transduction by p53 class mediator (GO:0030330)2.51405068
135positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.49588604
136cytochrome complex assembly (GO:0017004)2.49374767
137GTP biosynthetic process (GO:0006183)2.49053063
138nuclear-transcribed mRNA catabolic process (GO:0000956)2.48676943
139positive regulation of ligase activity (GO:0051351)2.47016410
140spliceosomal snRNP assembly (GO:0000387)2.46457084
141mitochondrial respiratory chain complex I assembly (GO:0032981)2.45040137
142NADH dehydrogenase complex assembly (GO:0010257)2.45040137
143mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.45040137
144response to interferon-beta (GO:0035456)2.45026379
145transcription from RNA polymerase I promoter (GO:0006360)2.42952586
146regulation of cellular amine metabolic process (GO:0033238)2.42678819
147metallo-sulfur cluster assembly (GO:0031163)2.42400881
148iron-sulfur cluster assembly (GO:0016226)2.42400881

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.56853098
2* KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.14145465
3SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.87254339
4GABP_17652178_ChIP-ChIP_JURKAT_Human3.66639957
5MYC_18555785_ChIP-Seq_MESCs_Mouse3.58551829
6FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.37347742
7* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.37259389
8EST1_17652178_ChIP-ChIP_JURKAT_Human3.36681360
9EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.18435156
10NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.10672533
11CREB1_15753290_ChIP-ChIP_HEK293T_Human3.03066740
12CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.00094472
13ETS1_20019798_ChIP-Seq_JURKAT_Human2.91911285
14ELF1_17652178_ChIP-ChIP_JURKAT_Human2.72071170
15MYC_18358816_ChIP-ChIP_MESCs_Mouse2.66096739
16CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.42982976
17VDR_23849224_ChIP-Seq_CD4+_Human2.38901035
18HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.35572062
19* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.34140381
20HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.33235090
21E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.27882999
22SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.18568925
23MYC_19079543_ChIP-ChIP_MESCs_Mouse2.18193153
24IRF8_22096565_ChIP-ChIP_GC-B_Human2.14189673
25SRF_21415370_ChIP-Seq_HL-1_Mouse2.14010587
26TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.11773144
27DCP1A_22483619_ChIP-Seq_HELA_Human2.10227687
28E2F1_18555785_ChIP-Seq_MESCs_Mouse2.07781167
29E2F4_17652178_ChIP-ChIP_JURKAT_Human2.06653420
30* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.05513449
31IRF8_21731497_ChIP-ChIP_J774_Mouse1.95453444
32FOXP3_21729870_ChIP-Seq_TREG_Human1.91367675
33IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.90747329
34* XRN2_22483619_ChIP-Seq_HELA_Human1.87943189
35FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.84128552
36ELK1_19687146_ChIP-ChIP_HELA_Human1.82711894
37NELFA_20434984_ChIP-Seq_ESCs_Mouse1.81822507
38* CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.79683450
39FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.79641834
40EGR1_23403033_ChIP-Seq_LIVER_Mouse1.78355793
41HOXB4_20404135_ChIP-ChIP_EML_Mouse1.77391438
42SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.74348805
43ERG_20887958_ChIP-Seq_HPC-7_Mouse1.64763941
44GABP_19822575_ChIP-Seq_HepG2_Human1.64300530
45* PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.63027131
46TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.62912215
47* CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.61195144
48TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.60964662
49YY1_21170310_ChIP-Seq_MESCs_Mouse1.56174965
50TTF2_22483619_ChIP-Seq_HELA_Human1.51694026
51* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.48342454
52ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.47725891
53SPI1_23547873_ChIP-Seq_NB4_Human1.42601206
54THAP11_20581084_ChIP-Seq_MESCs_Mouse1.40241413
55CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.38826311
56SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.37841530
57ZNF274_21170338_ChIP-Seq_K562_Hela1.33882669
58STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.31101513
59NOTCH1_21737748_ChIP-Seq_TLL_Human1.29914132
60PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.25504060
61STAT4_19710469_ChIP-ChIP_TH1__Mouse1.24117873
62ELK1_22589737_ChIP-Seq_MCF10A_Human1.23988813
63MYCN_18555785_ChIP-Seq_MESCs_Mouse1.21902094
64MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.20541538
65HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.20149610
66TP63_17297297_ChIP-ChIP_HaCaT_Human1.18872189
67VDR_22108803_ChIP-Seq_LS180_Human1.17633329
68NANOG_18555785_ChIP-Seq_MESCs_Mouse1.17135841
69ELF5_23300383_ChIP-Seq_T47D_Human1.16534085
70AR_21909140_ChIP-Seq_LNCAP_Human1.16043973
71POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.14284564
72TP53_22573176_ChIP-Seq_HFKS_Human1.13127230
73ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.11841372
74MYC_18940864_ChIP-ChIP_HL60_Human1.11839694
75ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.10644289
76TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.08678384
77ZFX_18555785_ChIP-Seq_MESCs_Mouse1.07395402
78SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.05775014
79ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.05074374
80AR_20517297_ChIP-Seq_VCAP_Human1.04935970
81IRF1_19129219_ChIP-ChIP_H3396_Human1.04621660
82HTT_18923047_ChIP-ChIP_STHdh_Human1.04479747
83E2F1_21310950_ChIP-Seq_MCF-7_Human1.02486728
84PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.02418557
85MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.01948765
86HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.00734947
87CTCF_18555785_ChIP-Seq_MESCs_Mouse1.00510889
88FOXA1_27270436_Chip-Seq_PROSTATE_Human0.99115299
89FOXA1_25329375_ChIP-Seq_VCAP_Human0.99115299
90MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.96835497
91ERG_20517297_ChIP-Seq_VCAP_Human0.95511204
92CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.95068414
93GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.94633815
94MYB_21317192_ChIP-Seq_ERMYB_Mouse0.93175416
95GATA1_22025678_ChIP-Seq_K562_Human0.93038177
96FOXM1_23109430_ChIP-Seq_U2OS_Human0.92113974
97POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.91940118
98BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.91771447
99RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.91681675
100KDM5A_27292631_Chip-Seq_BREAST_Human0.91670297
101EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.90886208
102YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.90260283
103* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.88796282
104* PADI4_21655091_ChIP-ChIP_MCF-7_Human0.88090794
105FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.87695106
106KAP1_22055183_ChIP-Seq_ESCs_Mouse0.87647255
107BP1_19119308_ChIP-ChIP_Hs578T_Human0.85869944
108GATA1_22383799_ChIP-Seq_G1ME_Mouse0.85284369
109DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.85051338
110FLI1_27457419_Chip-Seq_LIVER_Mouse0.84958495
111NANOG_20526341_ChIP-Seq_ESCs_Human0.84829790
112TFEB_21752829_ChIP-Seq_HELA_Human0.84780190
113PPARA_22158963_ChIP-Seq_LIVER_Mouse0.84290531
114ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.82790617
115SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.81987402
116IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.80688973
117SOX17_20123909_ChIP-Seq_XEN_Mouse0.79537259
118CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.79338577
119KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.78014000
120GATA3_21878914_ChIP-Seq_MCF-7_Human0.77728993
121RXR_22158963_ChIP-Seq_LIVER_Mouse0.77276220
122CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.77005552
123STAT3_1855785_ChIP-Seq_MESCs_Mouse0.76554555
124GATA2_22383799_ChIP-Seq_G1ME_Mouse0.76142152
125NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.75225142
126GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.75153935
127STAT1_20625510_ChIP-Seq_HELA_Human0.74672167
128EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.73471390
129GATA6_21074721_ChIP-Seq_CACO-2_Human0.73447710
130EWS_26573619_Chip-Seq_HEK293_Human0.72100472

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002163_abnormal_gland_morphology3.54673783
2MP0003806_abnormal_nucleotide_metabolis3.16441639
3MP0003693_abnormal_embryo_hatching3.10293548
4MP0005379_endocrine/exocrine_gland_phen2.93325949
5MP0003186_abnormal_redox_activity2.77993471
6MP0002837_dystrophic_cardiac_calcinosis2.74311931
7MP0005084_abnormal_gallbladder_morpholo2.61494170
8MP0009379_abnormal_foot_pigmentation2.55307339
9MP0008057_abnormal_DNA_replication2.53944405
10MP0001835_abnormal_antigen_presentation2.37331266
11MP0004381_abnormal_hair_follicle2.36748007
12MP0009785_altered_susceptibility_to2.29270778
13MP0002254_reproductive_system_inflammat2.23681064
14MP0008058_abnormal_DNA_repair2.17075933
15MP0003724_increased_susceptibility_to2.14129165
16MP0004957_abnormal_blastocyst_morpholog2.10383605
17MP0002148_abnormal_hypersensitivity_rea2.06875431
18MP0010094_abnormal_chromosome_stability1.94775494
19MP0010386_abnormal_urinary_bladder1.90246469
20MP0002396_abnormal_hematopoietic_system1.88590327
21MP0005671_abnormal_response_to1.87570215
22MP0005025_abnormal_response_to1.84387310
23MP0006072_abnormal_retinal_apoptosis1.81469533
24MP0002876_abnormal_thyroid_physiology1.79503951
25MP0008007_abnormal_cellular_replicative1.76278034
26MP0005451_abnormal_body_composition1.75496097
27MP0009333_abnormal_splenocyte_physiolog1.75411486
28MP0003718_maternal_effect1.74494610
29MP0003136_yellow_coat_color1.74099699
30MP0003111_abnormal_nucleus_morphology1.72984526
31MP0003077_abnormal_cell_cycle1.72137571
32MP0005075_abnormal_melanosome_morpholog1.70712477
33MP0005408_hypopigmentation1.69533254
34MP0002139_abnormal_hepatobiliary_system1.67904768
35MP0002132_abnormal_respiratory_system1.67039425
36MP0001853_heart_inflammation1.66188622
37MP0005000_abnormal_immune_tolerance1.64110246
38MP0003786_premature_aging1.61591669
39MP0003436_decreased_susceptibility_to1.58919422
40MP0006035_abnormal_mitochondrial_morpho1.58402511
41MP0003656_abnormal_erythrocyte_physiolo1.57501251
42MP0000685_abnormal_immune_system1.57022580
43MP0002419_abnormal_innate_immunity1.53732768
44MP0004147_increased_porphyrin_level1.52166771
45MP0005360_urolithiasis1.50214414
46MP0002693_abnormal_pancreas_physiology1.48860095
47MP0005645_abnormal_hypothalamus_physiol1.45885914
48MP0002723_abnormal_immune_serum1.45628472
49MP0003195_calcinosis1.42480951
50MP0003763_abnormal_thymus_physiology1.42241802
51MP0001800_abnormal_humoral_immune1.40199854
52MP0002452_abnormal_antigen_presenting1.39757220
53MP0008932_abnormal_embryonic_tissue1.38864258
54MP0001919_abnormal_reproductive_system1.34629379
55MP0001764_abnormal_homeostasis1.34341930
56MP0003123_paternal_imprinting1.33104211
57MP0002653_abnormal_ependyma_morphology1.32489813
58MP0004782_abnormal_surfactant_physiolog1.32310922
59MP0002420_abnormal_adaptive_immunity1.31356267
60MP0001819_abnormal_immune_cell1.30427034
61MP0008469_abnormal_protein_level1.26099382
62MP0002796_impaired_skin_barrier1.25894833
63MP0001905_abnormal_dopamine_level1.25653326
64MP0005085_abnormal_gallbladder_physiolo1.25130562
65MP0000490_abnormal_crypts_of1.24772038
66MP0009764_decreased_sensitivity_to1.22507791
67MP0008875_abnormal_xenobiotic_pharmacok1.19308464
68MP0005310_abnormal_salivary_gland1.18820695
69MP0001845_abnormal_inflammatory_respons1.15943553
70MP0005387_immune_system_phenotype1.15749717
71MP0001790_abnormal_immune_system1.15749717
72MP0002405_respiratory_system_inflammati1.15196900
73MP0000689_abnormal_spleen_morphology1.14987257
74MP0002277_abnormal_respiratory_mucosa1.14418026
75MP0001756_abnormal_urination1.14213069
76MP0000858_altered_metastatic_potential1.14000431
77MP0005389_reproductive_system_phenotype1.12379249
78MP0010155_abnormal_intestine_physiology1.11723787
79MP0000716_abnormal_immune_system1.11023501
80MP0009697_abnormal_copulation1.11015504
81MP0002398_abnormal_bone_marrow1.10921208
82MP0008877_abnormal_DNA_methylation1.10765074
83MP0006082_CNS_inflammation1.09617357
84MP0002722_abnormal_immune_system1.09164313
85MP0003941_abnormal_skin_development1.09038787
86MP0003315_abnormal_perineum_morphology1.09034186
87MP0006036_abnormal_mitochondrial_physio1.08361193
88MP0001944_abnormal_pancreas_morphology1.07795464
89MP0008872_abnormal_physiological_respon1.06867332
90MP0005319_abnormal_enzyme/_coenzyme1.06518787
91MP0002429_abnormal_blood_cell1.05634063
92MP0002006_tumorigenesis1.05493614
93MP0000358_abnormal_cell_content/1.03889287
94MP0008260_abnormal_autophagy1.03432915
95MP0005501_abnormal_skin_physiology1.02290095
96MP0002098_abnormal_vibrissa_morphology1.01525460
97MP0003866_abnormal_defecation1.01108325
98MP0005083_abnormal_biliary_tract1.00932635
99MP0005464_abnormal_platelet_physiology1.00723084
100MP0001542_abnormal_bone_strength0.97522063
101MP0000383_abnormal_hair_follicle0.97059359
102MP0000372_irregular_coat_pigmentation0.95909609
103MP0001666_abnormal_nutrient_absorption0.95839620
104MP0010234_abnormal_vibrissa_follicle0.95577025
105MP0004019_abnormal_vitamin_homeostasis0.95050612
106MP0005397_hematopoietic_system_phenotyp0.94992256
107MP0001545_abnormal_hematopoietic_system0.94992256
108MP0006054_spinal_hemorrhage0.94876017
109MP0003011_delayed_dark_adaptation0.94685338
110MP0009840_abnormal_foam_cell0.94273209
111MP0002166_altered_tumor_susceptibility0.93731749
112MP0005636_abnormal_mineral_homeostasis0.92904967
113MP0004947_skin_inflammation0.91465355
114MP0008789_abnormal_olfactory_epithelium0.91206625
115MP0003787_abnormal_imprinting0.91138337
116MP0002019_abnormal_tumor_incidence0.89654083
117MP0009643_abnormal_urine_homeostasis0.89414242
118MP0005551_abnormal_eye_electrophysiolog0.89199501
119MP0001873_stomach_inflammation0.88847221
120MP0005058_abnormal_lysosome_morphology0.88151502
121MP0002090_abnormal_vision0.87166717
122MP0000427_abnormal_hair_cycle0.86913419
123MP0002138_abnormal_hepatobiliary_system0.86406899
124MP0005365_abnormal_bile_salt0.86349159
125MP0002938_white_spotting0.85974382
126MP0005410_abnormal_fertilization0.84854917
127MP0002909_abnormal_adrenal_gland0.84116587
128MP0009765_abnormal_xenobiotic_induced0.83429695
129MP0001881_abnormal_mammary_gland0.83341992
130MP0000647_abnormal_sebaceous_gland0.83197558
131MP0005253_abnormal_eye_physiology0.82785141
132MP0000538_abnormal_urinary_bladder0.81775979
133MP0001529_abnormal_vocalization0.81534758
134MP0002095_abnormal_skin_pigmentation0.81406352
135MP0005332_abnormal_amino_acid0.80991369
136MP0006292_abnormal_olfactory_placode0.80677750
137MP0001986_abnormal_taste_sensitivity0.80551901
138MP0002736_abnormal_nociception_after0.80338424
139MP0001216_abnormal_epidermal_layer0.80301523
140MP0009763_increased_sensitivity_to0.80029123
141MP0001765_abnormal_ion_homeostasis0.78220136
142MP0000465_gastrointestinal_hemorrhage0.74409680
143MP0000566_synostosis0.74346875
144MP0000313_abnormal_cell_death0.74245456
145MP0001727_abnormal_embryo_implantation0.72497253
146MP0002160_abnormal_reproductive_system0.71768798
147MP0003950_abnormal_plasma_membrane0.70479950
148MP0008995_early_reproductive_senescence0.70332174

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)4.40195208
2Abnormal number of erythroid precursors (HP:0012131)4.38456508
3Reticulocytopenia (HP:0001896)3.64442576
43-Methylglutaconic aciduria (HP:0003535)3.50747309
5Macrocytic anemia (HP:0001972)3.23798063
6Parakeratosis (HP:0001036)3.15511545
7Increased hepatocellular lipid droplets (HP:0006565)3.00442414
8Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.92124287
9Hepatocellular necrosis (HP:0001404)2.91885000
10Lipid accumulation in hepatocytes (HP:0006561)2.90693901
11Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.89387201
12Mitochondrial inheritance (HP:0001427)2.88755507
13Hepatic necrosis (HP:0002605)2.88613617
14Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.78591633
15Decreased activity of mitochondrial respiratory chain (HP:0008972)2.78591633
16Type I transferrin isoform profile (HP:0003642)2.76479942
17Oral leukoplakia (HP:0002745)2.76110548
18Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.75569180
19Renal Fanconi syndrome (HP:0001994)2.74856183
20Acute necrotizing encephalopathy (HP:0006965)2.71418423
21Pallor (HP:0000980)2.71399008
22Reduced antithrombin III activity (HP:0001976)2.68467843
23Pancreatic cysts (HP:0001737)2.68436652
24Optic disc pallor (HP:0000543)2.67421454
25Aplastic anemia (HP:0001915)2.65650765
26Congenital ichthyosiform erythroderma (HP:0007431)2.64785839
27Aplasia/Hypoplasia of the sacrum (HP:0008517)2.63459529
28Increased CSF lactate (HP:0002490)2.62963131
29Recurrent abscess formation (HP:0002722)2.61763851
30Acute encephalopathy (HP:0006846)2.56833726
31Abnormality of midbrain morphology (HP:0002418)2.56740360
32Molar tooth sign on MRI (HP:0002419)2.56740360
33Increased serum lactate (HP:0002151)2.50933943
34Exertional dyspnea (HP:0002875)2.50928426
35Congenital, generalized hypertrichosis (HP:0004540)2.48462265
36Pancreatic fibrosis (HP:0100732)2.47491916
37Elevated erythrocyte sedimentation rate (HP:0003565)2.46672912
38Methylmalonic aciduria (HP:0012120)2.45542290
39Petechiae (HP:0000967)2.45249072
40Recurrent bacterial skin infections (HP:0005406)2.43779498
41Birth length less than 3rd percentile (HP:0003561)2.42635381
42Poor head control (HP:0002421)2.41130197
43Sparse eyelashes (HP:0000653)2.36886839
44Vacuolated lymphocytes (HP:0001922)2.36359211
45Leukodystrophy (HP:0002415)2.36235063
46Abnormal mitochondria in muscle tissue (HP:0008316)2.36186037
47Rough bone trabeculation (HP:0100670)2.35400082
48True hermaphroditism (HP:0010459)2.28655072
49Pancytopenia (HP:0001876)2.28559234
50IgM deficiency (HP:0002850)2.23931681
51Abnormality of aromatic amino acid family metabolism (HP:0004338)2.19518120
52Methylmalonic acidemia (HP:0002912)2.19215939
53Hepatosplenomegaly (HP:0001433)2.18806631
54Increased intramyocellular lipid droplets (HP:0012240)2.16657620
55Abnormal hemoglobin (HP:0011902)2.16453380
56Abnormality of the heme biosynthetic pathway (HP:0010472)2.15292113
57Breast hypoplasia (HP:0003187)2.15117240
58Prolonged neonatal jaundice (HP:0006579)2.14918504
59Cerebral hypomyelination (HP:0006808)2.12091318
60Hyperphosphaturia (HP:0003109)2.11704161
61Microretrognathia (HP:0000308)2.09454650
62Hypothermia (HP:0002045)2.08680347
63Abnormality of macrophages (HP:0004311)2.07536096
64Abnormal protein glycosylation (HP:0012346)2.07332597
65Abnormal glycosylation (HP:0012345)2.07332597
66Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.07332597
67Abnormal protein N-linked glycosylation (HP:0012347)2.07332597
68Abnormality of the axillary hair (HP:0100134)2.03971066
69Abnormality of secondary sexual hair (HP:0009888)2.03971066
70CNS demyelination (HP:0007305)2.02856885
71Progressive macrocephaly (HP:0004481)2.02803061
72Recurrent gram-negative bacterial infections (HP:0005420)2.01588320
73Respiratory difficulties (HP:0002880)2.01360798
74X-linked dominant inheritance (HP:0001423)2.01152744
75Eczematoid dermatitis (HP:0000976)1.99193196
76Increased muscle lipid content (HP:0009058)1.97361238
77Lactic acidosis (HP:0003128)1.97125153
78Glycosuria (HP:0003076)1.96065142
79Abnormality of urine glucose concentration (HP:0011016)1.96065142
80Abnormal trabecular bone morphology (HP:0100671)1.95738449
81Carpal bone hypoplasia (HP:0001498)1.95511086
82Testicular atrophy (HP:0000029)1.95047881
83Pustule (HP:0200039)1.94973928
84Hypokinesia (HP:0002375)1.94679639
85Cerebral edema (HP:0002181)1.94351667
86Thrombocytosis (HP:0001894)1.93817313
87Abnormality of renal resorption (HP:0011038)1.93645225
88Prolonged partial thromboplastin time (HP:0003645)1.93078292
89Ketoacidosis (HP:0001993)1.92896660
90Hypoplasia of the uterus (HP:0000013)1.92012590
91Microvesicular hepatic steatosis (HP:0001414)1.90188991
92Generalized aminoaciduria (HP:0002909)1.89914145
93Abnormality of placental membranes (HP:0011409)1.88758141
94Amniotic constriction ring (HP:0009775)1.88758141
95Steatorrhea (HP:0002570)1.88562805
96Abnormality of T cell physiology (HP:0011840)1.88053928
97Intrahepatic cholestasis (HP:0001406)1.87644982
98Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.87481858
99Abnormality of alanine metabolism (HP:0010916)1.87481858
100Hyperalaninemia (HP:0003348)1.87481858
101Nausea (HP:0002018)1.86516253
102Autoimmune hemolytic anemia (HP:0001890)1.84940077
103Respiratory failure (HP:0002878)1.84659761
104IgG deficiency (HP:0004315)1.82735810
105Medial flaring of the eyebrow (HP:0010747)1.82652632
106Exercise intolerance (HP:0003546)1.82135587
107Neutropenia (HP:0001875)1.81069500
108Premature graying of hair (HP:0002216)1.80403278
109Abnormality of monocarboxylic acid metabolism (HP:0010996)1.79922544
110Obstructive lung disease (HP:0006536)1.79145675
111Chronic obstructive pulmonary disease (HP:0006510)1.79145675
112Blindness (HP:0000618)1.77928561
113Abnormality of liposaccharide metabolism (HP:0010968)1.77764346
114Abnormality of glycosphingolipid metabolism (HP:0004343)1.77764346
115Abnormality of glycolipid metabolism (HP:0010969)1.77764346
116Abnormality of glycolysis (HP:0004366)1.77415466
117Increased serum pyruvate (HP:0003542)1.77415466
118Lymphoma (HP:0002665)1.76583724
119Erythroderma (HP:0001019)1.76284866
120Lethargy (HP:0001254)1.75532046
121Stomatitis (HP:0010280)1.75402562
122Aplasia/hypoplasia of the uterus (HP:0008684)1.75362259
123Abnormality of the anterior horn cell (HP:0006802)1.75305698
124Degeneration of anterior horn cells (HP:0002398)1.75305698
125Recurrent skin infections (HP:0001581)1.74506837
126Hyperinsulinemic hypoglycemia (HP:0000825)1.73850580
127Abnormality of methionine metabolism (HP:0010901)1.73716265
128Hyperglycinemia (HP:0002154)1.73317817
129Megaloblastic anemia (HP:0001889)1.73192143
130Abnormality of pyrimidine metabolism (HP:0004353)1.72370144
131Sclerocornea (HP:0000647)1.72195704
132Severe combined immunodeficiency (HP:0004430)1.72101910
133Increased IgM level (HP:0003496)1.71202446
13411 pairs of ribs (HP:0000878)1.70344843
135Combined immunodeficiency (HP:0005387)1.70028238
136Large for gestational age (HP:0001520)1.69420151
137Renal tubular dysfunction (HP:0000124)1.67363121
138Severe visual impairment (HP:0001141)1.67326312
139Vomiting (HP:0002013)1.66656376
140Palpitations (HP:0001962)1.66580467
141Hypoglycemic coma (HP:0001325)1.66560445
142Nephronophthisis (HP:0000090)1.65773220
143Abnormal rod and cone electroretinograms (HP:0008323)1.64316376
144Abnormality of aspartate family amino acid metabolism (HP:0010899)1.63515904
145Ketosis (HP:0001946)1.61724353
146Furrowed tongue (HP:0000221)1.61540519
147Dicarboxylic aciduria (HP:0003215)1.60648556
148Abnormality of dicarboxylic acid metabolism (HP:0010995)1.60648556

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK24.30357803
2STK163.71582517
3EIF2AK13.47148127
4PBK3.25082302
5NME23.20420749
6BUB13.09838053
7EIF2AK32.95867110
8WEE12.85382374
9MST42.39192827
10BLK2.21592427
11IRAK32.20341666
12VRK12.10692187
13NUAK12.10330940
14PIM22.06432441
15IRAK42.03059313
16TLK11.98558245
17TRIM281.87006363
18SRPK11.84130749
19TESK21.71744330
20FRK1.70650280
21MAP3K141.66478597
22KDR1.61262616
23MAP4K21.57682646
24ACVR1B1.54443046
25BRSK21.53114170
26INSRR1.48716506
27MAP4K11.48007731
28BCKDK1.45054607
29PLK41.43602298
30EPHA21.41402749
31EIF2AK21.40512343
32TXK1.38619193
33LIMK11.38133880
34PDK21.37315933
35TAF11.34147086
36TEC1.21985865
37IKBKE1.21606068
38IKBKB1.19868449
39DYRK31.17423715
40MKNK11.15730011
41TBK11.13244518
42ZAK1.13026114
43ZAP701.10193022
44MYLK1.10141880
45GRK71.08861832
46RPS6KB21.06420876
47CDC71.04324543
48PRKCI1.01477846
49WNK41.00958257
50MUSK0.98596458
51CSNK1G10.98584303
52ABL20.97109427
53STK390.96442969
54ARAF0.93207178
55WNK30.92912314
56BMPR1B0.91325906
57MAPKAPK50.89883053
58PAK40.89374026
59NEK10.88366427
60STK40.87610362
61ILK0.86673670
62YES10.86030462
63CDK70.84471496
64AURKB0.83609672
65TNIK0.82783583
66BCR0.80898429
67MAP3K30.80525009
68TYK20.80189410
69CSNK1G20.78931241
70PIM10.78856922
71DAPK10.78498985
72NME10.78112943
73RPS6KA40.77149545
74DYRK20.77109128
75TTK0.77096443
76BTK0.76959021
77PLK10.76152461
78CDK190.74406562
79MST1R0.74260874
80GRK10.73960164
81TSSK60.73563866
82AURKA0.73080947
83TAOK30.71903233
84MET0.71236041
85TESK10.70221308
86LYN0.69808855
87CLK10.68715647
88MKNK20.68109562
89RPS6KA50.67666030
90STK100.67551480
91CSNK1A1L0.67149293
92NLK0.65376039
93MAP3K110.64650283
94PINK10.64572936
95MAPKAPK30.64252071
96KIT0.63196746
97BRAF0.62479515
98CSNK2A10.58157848
99MAP3K80.58065296
100PRKCE0.57857432
101IRAK10.57285157
102LRRK20.57103916
103MAP2K20.56773478
104STK240.56325535
105MAP2K60.56066640
106NEK90.54745295
107ATR0.54580096
108BMPR20.53244378
109JAK30.53188028
110MAP3K120.52514388
111IRAK20.51367195
112ADRBK20.51052042
113DAPK30.50739363
114FER0.50359293
115SYK0.49771348
116ADRBK10.49767685
117CSNK1G30.48632215
118TIE10.48522062
119CSNK2A20.48515506
120CDK80.48441780
121NEK20.47664454
122OXSR10.47491196
123PAK30.47172919
124PRKCQ0.47012609
125ERN10.46982480
126STK38L0.46925305
127BRSK10.45927111
128SCYL20.44979461
129CSF1R0.43198266
130TRPM70.42843227
131MAP2K30.42575969
132MAP2K70.41857076
133LMTK20.40530782
134LCK0.40415145
135FLT30.39323909
136PLK30.38644205
137GRK50.37403382
138PHKG10.37287528
139PHKG20.37287528
140STK30.36636447
141MATK0.36578410
142PAK10.34655568
143CAMK2D0.32466926
144CSNK1A10.32132802
145TGFBR20.32030112
146ERBB30.31827091

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.00274548
2Proteasome_Homo sapiens_hsa030503.75283206
3DNA replication_Homo sapiens_hsa030302.94155248
4RNA polymerase_Homo sapiens_hsa030202.91043800
5Protein export_Homo sapiens_hsa030602.64901554
6Mismatch repair_Homo sapiens_hsa034302.30212962
7Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.19513442
8Pyrimidine metabolism_Homo sapiens_hsa002402.18149130
9Homologous recombination_Homo sapiens_hsa034402.08744275
10Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.08426261
11Folate biosynthesis_Homo sapiens_hsa007901.86218642
12Base excision repair_Homo sapiens_hsa034101.86155833
13Spliceosome_Homo sapiens_hsa030401.76535680
14Nucleotide excision repair_Homo sapiens_hsa034201.67898261
15Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.59490294
16Oxidative phosphorylation_Homo sapiens_hsa001901.58929650
17Collecting duct acid secretion_Homo sapiens_hsa049661.56752550
18Steroid biosynthesis_Homo sapiens_hsa001001.56199887
19Fatty acid elongation_Homo sapiens_hsa000621.52944337
20Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.47762757
21One carbon pool by folate_Homo sapiens_hsa006701.38365946
22Non-homologous end-joining_Homo sapiens_hsa034501.38314415
23Glutathione metabolism_Homo sapiens_hsa004801.38229279
24Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.37827282
25Cardiac muscle contraction_Homo sapiens_hsa042601.32764395
26Sulfur relay system_Homo sapiens_hsa041221.32523243
27Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.32376832
28Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.29459320
29Parkinsons disease_Homo sapiens_hsa050121.28696259
30Basal transcription factors_Homo sapiens_hsa030221.24834401
31Fanconi anemia pathway_Homo sapiens_hsa034601.20389902
32RNA transport_Homo sapiens_hsa030131.19315844
33Drug metabolism - other enzymes_Homo sapiens_hsa009831.16608795
34Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.12194379
35Rheumatoid arthritis_Homo sapiens_hsa053231.12024985
36Pentose and glucuronate interconversions_Homo sapiens_hsa000401.11912118
37Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.11673197
38Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.08961088
39Pentose phosphate pathway_Homo sapiens_hsa000301.07811561
40Purine metabolism_Homo sapiens_hsa002301.06383589
41Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.05317269
42Histidine metabolism_Homo sapiens_hsa003401.04438636
43Huntingtons disease_Homo sapiens_hsa050161.02346272
44RNA degradation_Homo sapiens_hsa030181.01910079
45Peroxisome_Homo sapiens_hsa041461.00054321
46Arachidonic acid metabolism_Homo sapiens_hsa005900.99666515
47Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.99370744
48Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.94161241
49Intestinal immune network for IgA production_Homo sapiens_hsa046720.92260271
50Chemical carcinogenesis_Homo sapiens_hsa052040.90909874
51Primary immunodeficiency_Homo sapiens_hsa053400.90506125
52Allograft rejection_Homo sapiens_hsa053300.89591312
53Retinol metabolism_Homo sapiens_hsa008300.88619362
54Vitamin B6 metabolism_Homo sapiens_hsa007500.88448897
55Sphingolipid metabolism_Homo sapiens_hsa006000.87103453
56Cyanoamino acid metabolism_Homo sapiens_hsa004600.86208819
57Propanoate metabolism_Homo sapiens_hsa006400.85955310
58Linoleic acid metabolism_Homo sapiens_hsa005910.84678895
59Cell cycle_Homo sapiens_hsa041100.84565936
60Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.84064616
61Graft-versus-host disease_Homo sapiens_hsa053320.83886601
62Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.83172188
63Staphylococcus aureus infection_Homo sapiens_hsa051500.82650435
64Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.81481367
65Vibrio cholerae infection_Homo sapiens_hsa051100.81313935
66N-Glycan biosynthesis_Homo sapiens_hsa005100.80718782
67Legionellosis_Homo sapiens_hsa051340.80683975
68Pyruvate metabolism_Homo sapiens_hsa006200.78609794
69Sulfur metabolism_Homo sapiens_hsa009200.78345177
70Steroid hormone biosynthesis_Homo sapiens_hsa001400.76285870
71p53 signaling pathway_Homo sapiens_hsa041150.76175952
72Caffeine metabolism_Homo sapiens_hsa002320.76172645
73Cysteine and methionine metabolism_Homo sapiens_hsa002700.76099018
74Herpes simplex infection_Homo sapiens_hsa051680.75943824
75Primary bile acid biosynthesis_Homo sapiens_hsa001200.75474856
76Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.75320436
77NF-kappa B signaling pathway_Homo sapiens_hsa040640.75262960
78Butanoate metabolism_Homo sapiens_hsa006500.74827320
79Antigen processing and presentation_Homo sapiens_hsa046120.73870621
80Selenocompound metabolism_Homo sapiens_hsa004500.72675371
81Alzheimers disease_Homo sapiens_hsa050100.72165176
82Metabolic pathways_Homo sapiens_hsa011000.71807026
83Regulation of autophagy_Homo sapiens_hsa041400.71190571
84Mineral absorption_Homo sapiens_hsa049780.68626085
85Hematopoietic cell lineage_Homo sapiens_hsa046400.68588631
86Type I diabetes mellitus_Homo sapiens_hsa049400.68527073
87Epstein-Barr virus infection_Homo sapiens_hsa051690.68483637
88Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.68264454
89Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.67876407
90Vitamin digestion and absorption_Homo sapiens_hsa049770.67323187
91Systemic lupus erythematosus_Homo sapiens_hsa053220.66761833
92Ether lipid metabolism_Homo sapiens_hsa005650.65601783
93RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.65533618
94alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.65473624
95Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.64547261
96Asthma_Homo sapiens_hsa053100.63237129
97NOD-like receptor signaling pathway_Homo sapiens_hsa046210.62476035
98Other glycan degradation_Homo sapiens_hsa005110.60463726
99Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.60344578
100beta-Alanine metabolism_Homo sapiens_hsa004100.60047292
101Autoimmune thyroid disease_Homo sapiens_hsa053200.58290093
102Measles_Homo sapiens_hsa051620.57741864
103Arginine and proline metabolism_Homo sapiens_hsa003300.57561665
104Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.57274892
105Phenylalanine metabolism_Homo sapiens_hsa003600.57153145
106Tyrosine metabolism_Homo sapiens_hsa003500.57043859
107SNARE interactions in vesicular transport_Homo sapiens_hsa041300.56315339
108Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.54388107
109Nitrogen metabolism_Homo sapiens_hsa009100.53729624
110Lysosome_Homo sapiens_hsa041420.53238307
111Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.52864613
112Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.51548179
113Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.50911061
114Phototransduction_Homo sapiens_hsa047440.50521213
115Leishmaniasis_Homo sapiens_hsa051400.50132632
116Malaria_Homo sapiens_hsa051440.48245558
117Complement and coagulation cascades_Homo sapiens_hsa046100.47984879
118Tryptophan metabolism_Homo sapiens_hsa003800.42808186
119Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.42355160
120Maturity onset diabetes of the young_Homo sapiens_hsa049500.40555823
121Fatty acid metabolism_Homo sapiens_hsa012120.38283400
122Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.32428626
123Fatty acid degradation_Homo sapiens_hsa000710.32372571

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