Rank | Gene Set | Z-score |
---|---|---|
1 | cilium or flagellum-dependent cell motility (GO:0001539) | 8.43829845 |
2 | axonemal dynein complex assembly (GO:0070286) | 8.11232831 |
3 | epithelial cilium movement (GO:0003351) | 7.52144839 |
4 | cilium movement (GO:0003341) | 7.27241436 |
5 | sperm motility (GO:0030317) | 7.16112315 |
6 | acrosome reaction (GO:0007340) | 7.02153259 |
7 | motile cilium assembly (GO:0044458) | 6.97527350 |
8 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 6.65205325 |
9 | acrosome assembly (GO:0001675) | 6.55402739 |
10 | fusion of sperm to egg plasma membrane (GO:0007342) | 6.37023799 |
11 | regulation of cilium movement (GO:0003352) | 6.22752894 |
12 | multicellular organism reproduction (GO:0032504) | 5.78247544 |
13 | cell wall macromolecule metabolic process (GO:0044036) | 5.73029325 |
14 | cell wall macromolecule catabolic process (GO:0016998) | 5.73029325 |
15 | sperm-egg recognition (GO:0035036) | 5.60136413 |
16 | protein localization to cilium (GO:0061512) | 5.43063760 |
17 | microtubule bundle formation (GO:0001578) | 5.30166939 |
18 | spermatid development (GO:0007286) | 5.17273290 |
19 | plasma membrane fusion (GO:0045026) | 5.14239112 |
20 | binding of sperm to zona pellucida (GO:0007339) | 5.01893255 |
21 | cell-cell recognition (GO:0009988) | 4.95693149 |
22 | piRNA metabolic process (GO:0034587) | 4.93127027 |
23 | reproduction (GO:0000003) | 4.61046006 |
24 | calcium ion-dependent exocytosis (GO:0017156) | 4.57721151 |
25 | male meiosis (GO:0007140) | 4.55430003 |
26 | ventricular system development (GO:0021591) | 4.53981194 |
27 | axoneme assembly (GO:0035082) | 4.49909599 |
28 | sensory perception of smell (GO:0007608) | 4.47126419 |
29 | intraciliary transport (GO:0042073) | 4.44703406 |
30 | single fertilization (GO:0007338) | 4.40641915 |
31 | neuron cell-cell adhesion (GO:0007158) | 4.23550101 |
32 | microtubule severing (GO:0051013) | 4.11955992 |
33 | sperm capacitation (GO:0048240) | 3.91617145 |
34 | presynaptic membrane assembly (GO:0097105) | 3.86888715 |
35 | primary alcohol catabolic process (GO:0034310) | 3.86511349 |
36 | microtubule depolymerization (GO:0007019) | 3.82627387 |
37 | negative regulation of inclusion body assembly (GO:0090084) | 3.82402962 |
38 | nonmotile primary cilium assembly (GO:0035058) | 3.82202727 |
39 | synaptonemal complex organization (GO:0070193) | 3.80437619 |
40 | protein polyglutamylation (GO:0018095) | 3.74516333 |
41 | vocalization behavior (GO:0071625) | 3.69802906 |
42 | cilium assembly (GO:0042384) | 3.66928443 |
43 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 3.64674623 |
44 | cilium organization (GO:0044782) | 3.64463969 |
45 | cell projection assembly (GO:0030031) | 3.62122610 |
46 | fertilization (GO:0009566) | 3.57976269 |
47 | regulation of microtubule-based movement (GO:0060632) | 3.56469838 |
48 | protein localization to synapse (GO:0035418) | 3.55680671 |
49 | cilium morphogenesis (GO:0060271) | 3.50505117 |
50 | spermatogenesis (GO:0007283) | 3.49933724 |
51 | male gamete generation (GO:0048232) | 3.48349732 |
52 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 3.48170013 |
53 | determination of left/right symmetry (GO:0007368) | 3.47147786 |
54 | DNA methylation involved in gamete generation (GO:0043046) | 3.46702208 |
55 | postsynaptic membrane organization (GO:0001941) | 3.46080350 |
56 | smoothened signaling pathway (GO:0007224) | 3.41803412 |
57 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.39832131 |
58 | presynaptic membrane organization (GO:0097090) | 3.38812223 |
59 | synaptonemal complex assembly (GO:0007130) | 3.37857291 |
60 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 3.32312659 |
61 | determination of bilateral symmetry (GO:0009855) | 3.31583122 |
62 | cell recognition (GO:0008037) | 3.29774972 |
63 | vitamin transmembrane transport (GO:0035461) | 3.29696047 |
64 | regulation of inclusion body assembly (GO:0090083) | 3.25397573 |
65 | specification of symmetry (GO:0009799) | 3.25044532 |
66 | GTP biosynthetic process (GO:0006183) | 3.25021768 |
67 | nucleoside diphosphate phosphorylation (GO:0006165) | 3.24466383 |
68 | gamete generation (GO:0007276) | 3.21086480 |
69 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 3.21081371 |
70 | regulation of glutamate receptor signaling pathway (GO:1900449) | 3.17870352 |
71 | startle response (GO:0001964) | 3.12708455 |
72 | cellular component assembly involved in morphogenesis (GO:0010927) | 3.11470354 |
73 | ethanol metabolic process (GO:0006067) | 3.09142176 |
74 | diterpenoid biosynthetic process (GO:0016102) | 3.05897881 |
75 | spermatid nucleus differentiation (GO:0007289) | 3.03828405 |
76 | membrane depolarization during action potential (GO:0086010) | 3.03266589 |
77 | retinal rod cell development (GO:0046548) | 3.03234161 |
78 | photoreceptor cell maintenance (GO:0045494) | 3.02039944 |
79 | male meiosis I (GO:0007141) | 3.00893016 |
80 | cytoplasmic microtubule organization (GO:0031122) | 2.99269934 |
81 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 2.97590756 |
82 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 2.95355796 |
83 | lung epithelium development (GO:0060428) | 2.94673618 |
84 | left/right pattern formation (GO:0060972) | 2.94221296 |
85 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 2.94060029 |
86 | one-carbon compound transport (GO:0019755) | 2.93266955 |
87 | germ cell development (GO:0007281) | 2.87716816 |
88 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.87622024 |
89 | centriole replication (GO:0007099) | 2.87558316 |
90 | negative regulation of T cell differentiation in thymus (GO:0033085) | 2.85237334 |
91 | sensory perception of chemical stimulus (GO:0007606) | 2.84994131 |
92 | cellular process involved in reproduction in multicellular organism (GO:0022412) | 2.83480834 |
93 | regulation of protein kinase A signaling (GO:0010738) | 2.83003256 |
94 | glutamate secretion (GO:0014047) | 2.82465401 |
95 | synaptic vesicle exocytosis (GO:0016079) | 2.82461333 |
96 | synaptic transmission, glutamatergic (GO:0035249) | 2.81567912 |
97 | microtubule-based movement (GO:0007018) | 2.79723996 |
98 | pyrimidine-containing compound transmembrane transport (GO:0072531) | 2.79525693 |
99 | regulation of synaptic vesicle exocytosis (GO:2000300) | 2.79524928 |
100 | glutamate receptor signaling pathway (GO:0007215) | 2.78558776 |
101 | organic cation transport (GO:0015695) | 2.78415534 |
102 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 2.77523736 |
103 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 2.76612171 |
104 | glutathione derivative biosynthetic process (GO:1901687) | 2.76007745 |
105 | glutathione derivative metabolic process (GO:1901685) | 2.76007745 |
106 | response to auditory stimulus (GO:0010996) | 2.75294201 |
107 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 2.72459304 |
108 | neuron-neuron synaptic transmission (GO:0007270) | 2.71189911 |
109 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 2.70904627 |
110 | lateral ventricle development (GO:0021670) | 2.68991038 |
111 | negative regulation of appetite (GO:0032099) | 2.68987195 |
112 | negative regulation of response to food (GO:0032096) | 2.68987195 |
113 | regulation of autophagic vacuole assembly (GO:2000785) | 2.68690365 |
114 | left/right axis specification (GO:0070986) | 2.68324910 |
115 | brain morphogenesis (GO:0048854) | 2.67471258 |
116 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 2.66499766 |
117 | gamma-aminobutyric acid transport (GO:0015812) | 2.66100045 |
118 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 2.65924018 |
119 | aldehyde catabolic process (GO:0046185) | 2.65008139 |
120 | centriole assembly (GO:0098534) | 2.63166036 |
121 | microtubule-based process (GO:0007017) | 2.62678252 |
122 | cornea development in camera-type eye (GO:0061303) | 2.60961436 |
123 | calcium ion import (GO:0070509) | 2.58370665 |
124 | neuronal action potential propagation (GO:0019227) | 2.57507792 |
125 | regulation of collateral sprouting (GO:0048670) | 2.56536196 |
126 | detection of calcium ion (GO:0005513) | 2.55615451 |
127 | terpenoid biosynthetic process (GO:0016114) | 2.55340400 |
128 | UTP biosynthetic process (GO:0006228) | 2.54563042 |
129 | urinary tract smooth muscle contraction (GO:0014848) | 2.54170980 |
130 | neurotransmitter catabolic process (GO:0042135) | 2.54069136 |
131 | establishment of tissue polarity (GO:0007164) | 2.53297097 |
132 | establishment of planar polarity (GO:0001736) | 2.53297097 |
133 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 2.53281929 |
134 | multicellular organismal reproductive process (GO:0048609) | 2.53090501 |
135 | regulation of microtubule depolymerization (GO:0031114) | 2.46298015 |
136 | establishment or maintenance of monopolar cell polarity (GO:0061339) | 2.43948791 |
137 | establishment of monopolar cell polarity (GO:0061162) | 2.43948791 |
138 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.43017981 |
139 | positive regulation of smoothened signaling pathway (GO:0045880) | 2.42898159 |
140 | retinoic acid metabolic process (GO:0042573) | 2.42870780 |
141 | ethanol oxidation (GO:0006069) | 2.42587917 |
142 | short-term memory (GO:0007614) | 2.42217172 |
143 | microtubule-based transport (GO:0010970) | 2.39271543 |
144 | organelle assembly (GO:0070925) | 2.38034681 |
145 | apical protein localization (GO:0045176) | 2.37162525 |
146 | retinol metabolic process (GO:0042572) | 2.34192052 |
147 | limb development (GO:0060173) | 2.33250094 |
148 | appendage development (GO:0048736) | 2.33250094 |
149 | transmission of nerve impulse (GO:0019226) | 2.32668144 |
150 | cytoskeleton-dependent intracellular transport (GO:0030705) | 2.30525837 |
151 | retinal ganglion cell axon guidance (GO:0031290) | 2.27640626 |
152 | microtubule polymerization or depolymerization (GO:0031109) | 2.27342212 |
153 | regulation of vacuole organization (GO:0044088) | 2.20743181 |
154 | auditory behavior (GO:0031223) | 2.20449661 |
155 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.18881710 |
156 | response to xenobiotic stimulus (GO:0009410) | 2.16212457 |
157 | regulation of type B pancreatic cell apoptotic process (GO:2000674) | 2.13574089 |
158 | protein neddylation (GO:0045116) | 2.13440645 |
159 | axonal fasciculation (GO:0007413) | 2.12502509 |
160 | retinal cone cell development (GO:0046549) | 2.12312642 |
161 | regulation of smoothened signaling pathway (GO:0008589) | 2.12034584 |
162 | lateral sprouting from an epithelium (GO:0060601) | 2.11757081 |
163 | mechanosensory behavior (GO:0007638) | 2.11687985 |
164 | positive regulation of mitochondrial fission (GO:0090141) | 2.11067758 |
165 | positive regulation of gastrulation (GO:2000543) | 2.10780974 |
166 | behavioral response to nicotine (GO:0035095) | 2.09712808 |
167 | negative regulation of microtubule depolymerization (GO:0007026) | 2.09473299 |
168 | regulation of appetite (GO:0032098) | 2.08439734 |
169 | neural tube formation (GO:0001841) | 2.08368833 |
170 | primary alcohol metabolic process (GO:0034308) | 2.07059259 |
171 | telencephalon development (GO:0021537) | 2.06892175 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 6.02258660 |
2 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 4.42860401 |
3 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.54148592 |
4 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.38188923 |
5 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.20378488 |
6 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.77204256 |
7 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.58615112 |
8 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.34329810 |
9 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.32829363 |
10 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.21233579 |
11 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.19070789 |
12 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 2.12162699 |
13 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.10538326 |
14 | VDR_22108803_ChIP-Seq_LS180_Human | 2.00107364 |
15 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.97954409 |
16 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.95740627 |
17 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.95682397 |
18 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.92887552 |
19 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.89339349 |
20 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.83725689 |
21 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.82472342 |
22 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.80940020 |
23 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.80898847 |
24 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.73043796 |
25 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.72010445 |
26 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.71066136 |
27 | P300_19829295_ChIP-Seq_ESCs_Human | 1.66972236 |
28 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.66747411 |
29 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.66624294 |
30 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.64788974 |
31 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.64318457 |
32 | * SMAD4_21799915_ChIP-Seq_A2780_Human | 1.63985817 |
33 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.63282610 |
34 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.61196692 |
35 | * CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.61141597 |
36 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.60984485 |
37 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.58992749 |
38 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.58978523 |
39 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.57851657 |
40 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.54930104 |
41 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.54719308 |
42 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.54292583 |
43 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.53820105 |
44 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.53378270 |
45 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.51884448 |
46 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.50532563 |
47 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.50211346 |
48 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.49290842 |
49 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.49290842 |
50 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.48360661 |
51 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.47837078 |
52 | FUS_26573619_Chip-Seq_HEK293_Human | 1.46449523 |
53 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.45194353 |
54 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.45194353 |
55 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.42697501 |
56 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.42562674 |
57 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.40882020 |
58 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.39483882 |
59 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.39427961 |
60 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.38329697 |
61 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.34470497 |
62 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.34380330 |
63 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.33957300 |
64 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.32949762 |
65 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.32630616 |
66 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.32410923 |
67 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.32084283 |
68 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.31270681 |
69 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.30886637 |
70 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.30683605 |
71 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.29570001 |
72 | EWS_26573619_Chip-Seq_HEK293_Human | 1.29543118 |
73 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.28163514 |
74 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.28061583 |
75 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.27862508 |
76 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.27618317 |
77 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.26950816 |
78 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.26399067 |
79 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.26087007 |
80 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.25840790 |
81 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.25777745 |
82 | KDM2B_26808549_Chip-Seq_REH_Human | 1.25639485 |
83 | * SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.24951318 |
84 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.24518841 |
85 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.24505844 |
86 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.22360967 |
87 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.22300223 |
88 | TCF4_23295773_ChIP-Seq_U87_Human | 1.22189050 |
89 | * HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.21122232 |
90 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.20287212 |
91 | AR_25329375_ChIP-Seq_VCAP_Human | 1.18866209 |
92 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.18316235 |
93 | STAT3_23295773_ChIP-Seq_U87_Human | 1.17405085 |
94 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 1.16543671 |
95 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 1.15388508 |
96 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.15278885 |
97 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.15011937 |
98 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.14378334 |
99 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.14036962 |
100 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.13264842 |
101 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 1.12953546 |
102 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.12395735 |
103 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.12323199 |
104 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.11843128 |
105 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.11045654 |
106 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.11014940 |
107 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.11014940 |
108 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.10400857 |
109 | SOX9_26525672_Chip-Seq_HEART_Mouse | 1.10025442 |
110 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.09022792 |
111 | PU1_27457419_Chip-Seq_LIVER_Mouse | 1.08865190 |
112 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.08657460 |
113 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.08036057 |
114 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.07790302 |
115 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.07210637 |
116 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.06583235 |
117 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.04985383 |
118 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.04985383 |
119 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.03534106 |
120 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.02650249 |
121 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.01438088 |
122 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.00263396 |
123 | * PHF8_20622853_ChIP-Seq_HELA_Human | 0.98443683 |
124 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.95983876 |
125 | * ETV1_20927104_ChIP-Seq_GIST48_Human | 0.94862035 |
126 | * TBL1_22424771_ChIP-Seq_293T_Human | 0.92366388 |
127 | * NCOR_22424771_ChIP-Seq_293T_Human | 0.92332422 |
128 | * PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 0.91838041 |
129 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.91233175 |
130 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 0.90545555 |
131 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.89483919 |
132 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 0.88650700 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0005410_abnormal_fertilization | 6.55479108 |
2 | MP0001984_abnormal_olfaction | 4.37819193 |
3 | MP0003880_abnormal_central_pattern | 4.11805368 |
4 | MP0004859_abnormal_synaptic_plasticity | 3.02150786 |
5 | MP0004133_heterotaxia | 2.86122486 |
6 | MP0008875_abnormal_xenobiotic_pharmacok | 2.81698137 |
7 | MP0005646_abnormal_pituitary_gland | 2.77421606 |
8 | MP0003698_abnormal_male_reproductive | 2.75139429 |
9 | MP0009046_muscle_twitch | 2.69146076 |
10 | MP0003635_abnormal_synaptic_transmissio | 2.64871812 |
11 | MP0005423_abnormal_somatic_nervous | 2.55944246 |
12 | MP0009745_abnormal_behavioral_response | 2.41721087 |
13 | MP0001968_abnormal_touch/_nociception | 2.34450480 |
14 | MP0002063_abnormal_learning/memory/cond | 2.28915728 |
15 | MP0001486_abnormal_startle_reflex | 2.22913980 |
16 | MP0002572_abnormal_emotion/affect_behav | 2.22368123 |
17 | MP0001929_abnormal_gametogenesis | 2.19038110 |
18 | MP0008877_abnormal_DNA_methylation | 2.16855613 |
19 | MP0002064_seizures | 2.16483733 |
20 | MP0010030_abnormal_orbit_morphology | 2.11901115 |
21 | MP0004270_analgesia | 2.10911836 |
22 | MP0005645_abnormal_hypothalamus_physiol | 2.10316344 |
23 | MP0001188_hyperpigmentation | 2.06139876 |
24 | MP0002736_abnormal_nociception_after | 2.06042829 |
25 | MP0002272_abnormal_nervous_system | 2.05176112 |
26 | MP0002734_abnormal_mechanical_nocicepti | 1.92892483 |
27 | MP0002735_abnormal_chemical_nociception | 1.87424341 |
28 | MP0006276_abnormal_autonomic_nervous | 1.84669093 |
29 | MP0004043_abnormal_pH_regulation | 1.75922068 |
30 | MP0002557_abnormal_social/conspecific_i | 1.73543066 |
31 | MP0002067_abnormal_sensory_capabilities | 1.70056767 |
32 | MP0001440_abnormal_grooming_behavior | 1.67012323 |
33 | MP0009379_abnormal_foot_pigmentation | 1.60502397 |
34 | MP0000778_abnormal_nervous_system | 1.60168373 |
35 | MP0001501_abnormal_sleep_pattern | 1.55877800 |
36 | MP0002822_catalepsy | 1.55864812 |
37 | MP0001529_abnormal_vocalization | 1.54748513 |
38 | MP0002210_abnormal_sex_determination | 1.54455780 |
39 | MP0005551_abnormal_eye_electrophysiolog | 1.53019781 |
40 | MP0002184_abnormal_innervation | 1.50405552 |
41 | MP0004742_abnormal_vestibular_system | 1.49947328 |
42 | MP0002102_abnormal_ear_morphology | 1.49734904 |
43 | MP0002277_abnormal_respiratory_mucosa | 1.47203404 |
44 | MP0002282_abnormal_trachea_morphology | 1.46214833 |
45 | MP0003136_yellow_coat_color | 1.44838326 |
46 | MP0002638_abnormal_pupillary_reflex | 1.40799134 |
47 | MP0006292_abnormal_olfactory_placode | 1.40210176 |
48 | MP0002876_abnormal_thyroid_physiology | 1.39224985 |
49 | MP0001502_abnormal_circadian_rhythm | 1.38556957 |
50 | MP0002161_abnormal_fertility/fecundity | 1.38288436 |
51 | MP0003787_abnormal_imprinting | 1.36887827 |
52 | MP0003011_delayed_dark_adaptation | 1.35426781 |
53 | MP0002909_abnormal_adrenal_gland | 1.35418423 |
54 | MP0002653_abnormal_ependyma_morphology | 1.35285251 |
55 | MP0002132_abnormal_respiratory_system | 1.32514847 |
56 | MP0002233_abnormal_nose_morphology | 1.32514800 |
57 | MP0002160_abnormal_reproductive_system | 1.31347158 |
58 | MP0004142_abnormal_muscle_tone | 1.30265176 |
59 | MP0005248_abnormal_Harderian_gland | 1.29932654 |
60 | MP0002928_abnormal_bile_duct | 1.28105922 |
61 | MP0001970_abnormal_pain_threshold | 1.27631168 |
62 | MP0001905_abnormal_dopamine_level | 1.24739066 |
63 | MP0005394_taste/olfaction_phenotype | 1.23189084 |
64 | MP0005499_abnormal_olfactory_system | 1.23189084 |
65 | MP0004019_abnormal_vitamin_homeostasis | 1.23062324 |
66 | MP0001986_abnormal_taste_sensitivity | 1.23059937 |
67 | MP0002938_white_spotting | 1.22922687 |
68 | MP0002882_abnormal_neuron_morphology | 1.21222523 |
69 | MP0000569_abnormal_digit_pigmentation | 1.20982854 |
70 | MP0003879_abnormal_hair_cell | 1.18901826 |
71 | MP0002733_abnormal_thermal_nociception | 1.17326347 |
72 | MP0008569_lethality_at_weaning | 1.17209687 |
73 | MP0001145_abnormal_male_reproductive | 1.15381779 |
74 | MP0001963_abnormal_hearing_physiology | 1.15068394 |
75 | MP0001485_abnormal_pinna_reflex | 1.14537855 |
76 | MP0004924_abnormal_behavior | 1.14452593 |
77 | MP0005386_behavior/neurological_phenoty | 1.14452593 |
78 | MP0000026_abnormal_inner_ear | 1.12760131 |
79 | MP0004811_abnormal_neuron_physiology | 1.09952833 |
80 | MP0003937_abnormal_limbs/digits/tail_de | 1.09759517 |
81 | MP0000631_abnormal_neuroendocrine_gland | 1.08324447 |
82 | MP0003890_abnormal_embryonic-extraembry | 1.08221142 |
83 | MP0009780_abnormal_chondrocyte_physiolo | 1.08087205 |
84 | MP0001293_anophthalmia | 1.06060048 |
85 | MP0002752_abnormal_somatic_nervous | 1.04869093 |
86 | MP0000653_abnormal_sex_gland | 1.04379796 |
87 | MP0004858_abnormal_nervous_system | 1.04212795 |
88 | MP0005171_absent_coat_pigmentation | 1.03233884 |
89 | MP0004147_increased_porphyrin_level | 1.02729386 |
90 | MP0008789_abnormal_olfactory_epithelium | 0.98992983 |
91 | MP0000383_abnormal_hair_follicle | 0.98498980 |
92 | MP0005409_darkened_coat_color | 0.97992643 |
93 | MP0002152_abnormal_brain_morphology | 0.96901921 |
94 | MP0002066_abnormal_motor_capabilities/c | 0.95742874 |
95 | MP0002249_abnormal_larynx_morphology | 0.95480830 |
96 | MP0000955_abnormal_spinal_cord | 0.95470028 |
97 | MP0005253_abnormal_eye_physiology | 0.95269523 |
98 | MP0001324_abnormal_eye_pigmentation | 0.94025856 |
99 | MP0003121_genomic_imprinting | 0.94017773 |
100 | MP0010386_abnormal_urinary_bladder | 0.93839306 |
101 | MP0000372_irregular_coat_pigmentation | 0.91517704 |
102 | MP0003283_abnormal_digestive_organ | 0.89543589 |
103 | MP0002090_abnormal_vision | 0.88258549 |
104 | MP0003122_maternal_imprinting | 0.87885949 |
105 | MP0004885_abnormal_endolymph | 0.82604345 |
106 | MP0000049_abnormal_middle_ear | 0.81751881 |
107 | MP0002229_neurodegeneration | 0.81190437 |
108 | MP0003633_abnormal_nervous_system | 0.79716761 |
109 | MP0005377_hearing/vestibular/ear_phenot | 0.79132588 |
110 | MP0003878_abnormal_ear_physiology | 0.79132588 |
111 | MP0005391_vision/eye_phenotype | 0.78829444 |
112 | MP0001346_abnormal_lacrimal_gland | 0.77589521 |
113 | MP0001299_abnormal_eye_distance/ | 0.77160375 |
114 | MP0005084_abnormal_gallbladder_morpholo | 0.76349232 |
115 | MP0005623_abnormal_meninges_morphology | 0.75689004 |
116 | MP0008995_early_reproductive_senescence | 0.73706761 |
117 | MP0003634_abnormal_glial_cell | 0.70802897 |
118 | MP0003631_nervous_system_phenotype | 0.69777181 |
119 | MP0000015_abnormal_ear_pigmentation | 0.68422779 |
120 | MP0003938_abnormal_ear_development | 0.68392682 |
121 | MP0006072_abnormal_retinal_apoptosis | 0.67185417 |
122 | MP0003183_abnormal_peptide_metabolism | 0.66869332 |
123 | MP0000566_synostosis | 0.66227389 |
124 | MP0005389_reproductive_system_phenotype | 0.66198853 |
125 | MP0001664_abnormal_digestion | 0.61134705 |
126 | MP0005195_abnormal_posterior_eye | 0.59851794 |
127 | MP0003861_abnormal_nervous_system | 0.57720193 |
128 | MP0001177_atelectasis | 0.57053621 |
129 | MP0002069_abnormal_eating/drinking_beha | 0.56282993 |
130 | MP0005379_endocrine/exocrine_gland_phen | 0.55867276 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 9.34221241 |
2 | Absent/shortened dynein arms (HP:0200106) | 9.34221241 |
3 | Abnormal respiratory motile cilium physiology (HP:0012261) | 8.07610176 |
4 | Abnormal respiratory motile cilium morphology (HP:0005938) | 7.35846691 |
5 | Abnormal respiratory epithelium morphology (HP:0012253) | 7.35846691 |
6 | Abnormal ciliary motility (HP:0012262) | 7.26442190 |
7 | Rhinitis (HP:0012384) | 6.23474657 |
8 | Chronic bronchitis (HP:0004469) | 5.00487866 |
9 | Nephronophthisis (HP:0000090) | 3.97948471 |
10 | Medial flaring of the eyebrow (HP:0010747) | 3.91400418 |
11 | Focal motor seizures (HP:0011153) | 3.82260798 |
12 | Infertility (HP:0000789) | 3.72340590 |
13 | Gait imbalance (HP:0002141) | 3.39141656 |
14 | Bronchiectasis (HP:0002110) | 3.35429750 |
15 | Congenital primary aphakia (HP:0007707) | 3.27308776 |
16 | Molar tooth sign on MRI (HP:0002419) | 3.18122616 |
17 | Abnormality of midbrain morphology (HP:0002418) | 3.18122616 |
18 | Abnormality of the renal medulla (HP:0100957) | 3.13192969 |
19 | Nephrogenic diabetes insipidus (HP:0009806) | 3.01358307 |
20 | Febrile seizures (HP:0002373) | 3.00228135 |
21 | True hermaphroditism (HP:0010459) | 2.99460908 |
22 | Epileptic encephalopathy (HP:0200134) | 2.90032705 |
23 | Pancreatic fibrosis (HP:0100732) | 2.87706638 |
24 | Tubulointerstitial nephritis (HP:0001970) | 2.76018636 |
25 | Nasal polyposis (HP:0100582) | 2.72219308 |
26 | Atonic seizures (HP:0010819) | 2.67709640 |
27 | Anencephaly (HP:0002323) | 2.66449598 |
28 | Genital tract atresia (HP:0001827) | 2.58343947 |
29 | Vaginal atresia (HP:0000148) | 2.56687883 |
30 | Retinal dysplasia (HP:0007973) | 2.53048465 |
31 | Median cleft lip (HP:0000161) | 2.49429786 |
32 | Focal seizures (HP:0007359) | 2.48033368 |
33 | Aplasia/Hypoplasia of the lens (HP:0008063) | 2.47847252 |
34 | Poor coordination (HP:0002370) | 2.39015168 |
35 | Postaxial foot polydactyly (HP:0001830) | 2.37760406 |
36 | Postaxial hand polydactyly (HP:0001162) | 2.35274715 |
37 | Hyperventilation (HP:0002883) | 2.34910675 |
38 | Bronchitis (HP:0012387) | 2.23034780 |
39 | Abnormality of permanent molar morphology (HP:0011071) | 2.21077411 |
40 | Abnormality of the dental root (HP:0006486) | 2.21077411 |
41 | Taurodontia (HP:0000679) | 2.21077411 |
42 | Abnormality of molar (HP:0011077) | 2.20969923 |
43 | Abnormality of molar morphology (HP:0011070) | 2.20969923 |
44 | Atelectasis (HP:0100750) | 2.17946532 |
45 | Hyperactive renin-angiotensin system (HP:0000841) | 2.17795804 |
46 | Recurrent sinusitis (HP:0011108) | 2.17520196 |
47 | Pancreatic cysts (HP:0001737) | 2.12282199 |
48 | Furrowed tongue (HP:0000221) | 2.12220701 |
49 | Abnormality of the dental pulp (HP:0006479) | 2.08493503 |
50 | Congenital hepatic fibrosis (HP:0002612) | 2.06094414 |
51 | Chronic hepatic failure (HP:0100626) | 2.00749230 |
52 | Hemiparesis (HP:0001269) | 2.00655489 |
53 | Limb dystonia (HP:0002451) | 2.00105576 |
54 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 10.1652327 |
55 | Gaze-evoked nystagmus (HP:0000640) | 1.97859823 |
56 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.94849384 |
57 | Chronic otitis media (HP:0000389) | 1.94539412 |
58 | Progressive cerebellar ataxia (HP:0002073) | 1.92633491 |
59 | Recurrent otitis media (HP:0000403) | 1.91752059 |
60 | Myokymia (HP:0002411) | 1.89865206 |
61 | Abnormality of the nasal mucosa (HP:0000433) | 1.87652219 |
62 | Oculomotor apraxia (HP:0000657) | 1.86804850 |
63 | Specific learning disability (HP:0001328) | 1.86650944 |
64 | Fibular hypoplasia (HP:0003038) | 1.83295386 |
65 | Cystic liver disease (HP:0006706) | 1.82531849 |
66 | Bifid tongue (HP:0010297) | 1.82021898 |
67 | Preaxial hand polydactyly (HP:0001177) | 1.81399750 |
68 | Decreased central vision (HP:0007663) | 1.80434379 |
69 | Abnormal hair whorl (HP:0010721) | 1.80144293 |
70 | Absence seizures (HP:0002121) | 1.79346208 |
71 | Stage 5 chronic kidney disease (HP:0003774) | 1.78491577 |
72 | Tubulointerstitial abnormality (HP:0001969) | 1.78241324 |
73 | Abnormal biliary tract physiology (HP:0012439) | 1.77253653 |
74 | Bile duct proliferation (HP:0001408) | 1.77253653 |
75 | Narrow forehead (HP:0000341) | 1.76950370 |
76 | Bell-shaped thorax (HP:0001591) | 1.76300532 |
77 | Occipital encephalocele (HP:0002085) | 1.73673030 |
78 | Decreased circulating renin level (HP:0003351) | 1.72414574 |
79 | Aplasia involving bones of the extremities (HP:0009825) | 1.72003987 |
80 | Aplasia involving bones of the upper limbs (HP:0009823) | 1.72003987 |
81 | Aplasia of the phalanges of the hand (HP:0009802) | 1.72003987 |
82 | Abnormality of the renal cortex (HP:0011035) | 1.71779484 |
83 | Dyschromatopsia (HP:0007641) | 1.68930319 |
84 | Chronic sinusitis (HP:0011109) | 1.68184014 |
85 | Facial cleft (HP:0002006) | 1.67945872 |
86 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.66840588 |
87 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.65856419 |
88 | Choroideremia (HP:0001139) | 1.65630273 |
89 | Dialeptic seizures (HP:0011146) | 1.65102786 |
90 | Generalized tonic-clonic seizures (HP:0002069) | 1.64351597 |
91 | Hypothermia (HP:0002045) | 1.63251854 |
92 | Aganglionic megacolon (HP:0002251) | 1.59428539 |
93 | Tubulointerstitial fibrosis (HP:0005576) | 1.59194312 |
94 | Morphological abnormality of the middle ear (HP:0008609) | 1.58555870 |
95 | Supernumerary spleens (HP:0009799) | 1.58217343 |
96 | Broad-based gait (HP:0002136) | 1.58190762 |
97 | Asplenia (HP:0001746) | 1.57252747 |
98 | Abnormality of dentin (HP:0010299) | 1.57157252 |
99 | Nephropathy (HP:0000112) | 1.55858873 |
100 | Sclerocornea (HP:0000647) | 1.54846564 |
101 | Prominent nasal bridge (HP:0000426) | 1.53654762 |
102 | Retinitis pigmentosa (HP:0000510) | 1.52915895 |
103 | Abnormality of macular pigmentation (HP:0008002) | 1.52376458 |
104 | Tubular atrophy (HP:0000092) | 1.52028698 |
105 | Optic nerve hypoplasia (HP:0000609) | 1.51617163 |
106 | Astigmatism (HP:0000483) | 1.49534575 |
107 | Male pseudohermaphroditism (HP:0000037) | 1.49485146 |
108 | Male infertility (HP:0003251) | 1.48073672 |
109 | Polyphagia (HP:0002591) | 1.47804261 |
110 | Narrow nasal bridge (HP:0000446) | 1.47785540 |
111 | Multicystic kidney dysplasia (HP:0000003) | 1.47633758 |
112 | Renal dysplasia (HP:0000110) | 1.45185284 |
113 | Left ventricular hypertrophy (HP:0001712) | 1.44610900 |
114 | Decreased testicular size (HP:0008734) | 1.44152632 |
115 | Broad foot (HP:0001769) | 1.43744662 |
116 | Short tibia (HP:0005736) | 1.42075786 |
117 | Abnormal drinking behavior (HP:0030082) | 1.41605895 |
118 | Polydipsia (HP:0001959) | 1.41605895 |
119 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.40652429 |
120 | Abdominal situs inversus (HP:0003363) | 1.32499984 |
121 | Abnormality of abdominal situs (HP:0011620) | 1.32499984 |
122 | Renal salt wasting (HP:0000127) | 1.31638845 |
123 | Anophthalmia (HP:0000528) | 1.31305690 |
124 | Short nail (HP:0001799) | 1.29122799 |
125 | Highly arched eyebrow (HP:0002553) | 1.27483852 |
126 | Hip dysplasia (HP:0001385) | 1.26075551 |
127 | Fetal akinesia sequence (HP:0001989) | 1.25740262 |
128 | Acute necrotizing encephalopathy (HP:0006965) | 1.25088266 |
129 | Broad distal phalanx of finger (HP:0009836) | 1.23219699 |
130 | Chorioretinal coloboma (HP:0000567) | 1.21937347 |
131 | Hyperaldosteronism (HP:0000859) | 1.21589847 |
132 | Short thorax (HP:0010306) | 1.20665130 |
133 | Labial hypoplasia (HP:0000066) | 1.20583732 |
Rank | Gene Set | Z-score |
---|---|---|
1 | CASK | 4.80642510 |
2 | PDK3 | 4.47642952 |
3 | PDK4 | 4.47642952 |
4 | PRKD3 | 3.06057075 |
5 | NTRK3 | 3.00798836 |
6 | PDK2 | 2.95959943 |
7 | EPHA4 | 2.57078982 |
8 | MAP4K2 | 2.54747256 |
9 | MAP2K7 | 2.52031304 |
10 | MST4 | 2.32261349 |
11 | TESK1 | 1.93430373 |
12 | EPHA2 | 1.90528914 |
13 | TNIK | 1.89993436 |
14 | ICK | 1.89711224 |
15 | MAP3K4 | 1.77906808 |
16 | PNCK | 1.75825086 |
17 | NTRK2 | 1.73542045 |
18 | PRPF4B | 1.71118150 |
19 | MAPK13 | 1.69921553 |
20 | FRK | 1.64481572 |
21 | MARK1 | 1.63280277 |
22 | PTK2B | 1.60239045 |
23 | MAPK15 | 1.54825263 |
24 | DAPK2 | 1.52960498 |
25 | MAP3K12 | 1.48931008 |
26 | STK39 | 1.46282314 |
27 | STK16 | 1.43838390 |
28 | BCKDK | 1.41339423 |
29 | CCNB1 | 1.41290867 |
30 | AKT3 | 1.39742548 |
31 | CSNK1G2 | 1.37254418 |
32 | PLK2 | 1.36592781 |
33 | PRKCG | 1.32872331 |
34 | NEK6 | 1.29346063 |
35 | STK38 | 1.25369422 |
36 | MINK1 | 1.24955195 |
37 | WNK4 | 1.20903121 |
38 | EPHB2 | 1.20182170 |
39 | CDK3 | 1.16045508 |
40 | SGK2 | 1.15089883 |
41 | ERBB3 | 1.12044304 |
42 | ADRBK2 | 1.11638465 |
43 | NME1 | 1.10621689 |
44 | MUSK | 1.09723159 |
45 | RIPK4 | 1.09511700 |
46 | DYRK3 | 1.09089645 |
47 | PRKCI | 1.06668972 |
48 | SIK3 | 1.06256939 |
49 | TTK | 1.06022150 |
50 | CSNK1G1 | 1.05856136 |
51 | LIMK1 | 1.05305913 |
52 | BMPR2 | 1.04317701 |
53 | CSNK1G3 | 1.04183484 |
54 | SGK223 | 1.02953687 |
55 | SGK494 | 1.02953687 |
56 | DYRK2 | 1.02587394 |
57 | DAPK1 | 0.98654321 |
58 | PAK3 | 0.97391390 |
59 | MAPKAPK3 | 0.95635635 |
60 | GRK7 | 0.93564713 |
61 | CAMK2A | 0.93040333 |
62 | PHKG1 | 0.92120349 |
63 | PHKG2 | 0.92120349 |
64 | CAMK2B | 0.89259545 |
65 | CSNK1A1L | 0.88865963 |
66 | STK24 | 0.86774150 |
67 | BCR | 0.86167865 |
68 | MAP3K2 | 0.83431072 |
69 | OXSR1 | 0.82805081 |
70 | GRK5 | 0.82013982 |
71 | PINK1 | 0.81878009 |
72 | TRIM28 | 0.81759058 |
73 | WNK3 | 0.80236506 |
74 | FGFR2 | 0.79184197 |
75 | TNK2 | 0.77703083 |
76 | CDK5 | 0.77263412 |
77 | BMPR1B | 0.73325720 |
78 | DYRK1A | 0.73303596 |
79 | PRKCE | 0.72793706 |
80 | IRAK1 | 0.71919153 |
81 | BRAF | 0.71778613 |
82 | TSSK6 | 0.71100483 |
83 | EPHA3 | 0.70409044 |
84 | YES1 | 0.69345828 |
85 | LMTK2 | 0.66085381 |
86 | MKNK2 | 0.64910238 |
87 | MAP2K4 | 0.64306342 |
88 | CAMK2D | 0.62358755 |
89 | CDK19 | 0.57964801 |
90 | PBK | 0.57467437 |
91 | IRAK2 | 0.57348547 |
92 | ERBB2 | 0.57083068 |
93 | MAPK7 | 0.56888894 |
94 | WNK1 | 0.56545170 |
95 | PAK6 | 0.56199378 |
96 | PKN1 | 0.55127582 |
97 | STK38L | 0.55075624 |
98 | CAMKK1 | 0.54241804 |
99 | INSRR | 0.53665951 |
100 | PDK1 | 0.53024859 |
101 | GRK1 | 0.52813392 |
102 | CDK18 | 0.52228772 |
103 | CAMK2G | 0.51343191 |
104 | CSNK1A1 | 0.51142434 |
105 | PRKCZ | 0.50442351 |
106 | PLK1 | 0.48266032 |
107 | LRRK2 | 0.48253770 |
108 | SGK3 | 0.47670176 |
109 | AURKA | 0.46877094 |
110 | CDK15 | 0.45120197 |
111 | CAMKK2 | 0.44374267 |
112 | VRK1 | 0.44201032 |
113 | PASK | 0.42105162 |
114 | SGK1 | 0.41780524 |
115 | BRSK2 | 0.41428425 |
116 | SIK2 | 0.40222835 |
117 | CAMK1 | 0.38811158 |
118 | KSR1 | 0.38430507 |
119 | ROCK2 | 0.38087153 |
120 | ADRBK1 | 0.37976673 |
121 | MAPKAPK5 | 0.37946826 |
122 | MET | 0.37908139 |
123 | WEE1 | 0.37677104 |
124 | DYRK1B | 0.37439916 |
125 | CDK11A | 0.37070109 |
126 | PRKG1 | 0.36855018 |
127 | CDK14 | 0.36475997 |
128 | CSNK1E | 0.36422922 |
129 | TLK1 | 0.35917433 |
130 | PRKACA | 0.34696370 |
131 | ARAF | 0.34454787 |
132 | FES | 0.34252376 |
133 | UHMK1 | 0.31242285 |
134 | RPS6KB1 | 0.31007215 |
135 | CAMK1G | 0.29136202 |
136 | PRKCA | 0.27749455 |
137 | STK11 | 0.26988975 |
138 | RPS6KA2 | 0.26544328 |
139 | MAPK12 | 0.25689449 |
140 | PDPK1 | 0.25512476 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Olfactory transduction_Homo sapiens_hsa04740 | 4.35470183 |
2 | Nicotine addiction_Homo sapiens_hsa05033 | 3.74728055 |
3 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 2.92960280 |
4 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.88285522 |
5 | Morphine addiction_Homo sapiens_hsa05032 | 2.56553000 |
6 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.52624265 |
7 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.51181003 |
8 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 2.44260564 |
9 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 2.41645465 |
10 | Circadian entrainment_Homo sapiens_hsa04713 | 2.34311241 |
11 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.32379722 |
12 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.30866666 |
13 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 2.29631008 |
14 | Phototransduction_Homo sapiens_hsa04744 | 2.26216801 |
15 | Taste transduction_Homo sapiens_hsa04742 | 2.24962298 |
16 | Histidine metabolism_Homo sapiens_hsa00340 | 2.21691818 |
17 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.18699721 |
18 | GABAergic synapse_Homo sapiens_hsa04727 | 2.11748359 |
19 | Insulin secretion_Homo sapiens_hsa04911 | 2.09755747 |
20 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 2.08050478 |
21 | Salivary secretion_Homo sapiens_hsa04970 | 1.96144617 |
22 | Long-term potentiation_Homo sapiens_hsa04720 | 1.92415699 |
23 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.91431298 |
24 | Renin secretion_Homo sapiens_hsa04924 | 1.83579986 |
25 | Protein export_Homo sapiens_hsa03060 | 1.81885521 |
26 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.77752340 |
27 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.73872144 |
28 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.71797754 |
29 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.70113107 |
30 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.64978839 |
31 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.55031640 |
32 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.54616204 |
33 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.53226666 |
34 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.50121806 |
35 | Peroxisome_Homo sapiens_hsa04146 | 1.46528783 |
36 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.38491573 |
37 | Cocaine addiction_Homo sapiens_hsa05030 | 1.37674867 |
38 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.36938305 |
39 | Retinol metabolism_Homo sapiens_hsa00830 | 1.36455231 |
40 | Huntingtons disease_Homo sapiens_hsa05016 | 1.36133523 |
41 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.35338133 |
42 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.30545668 |
43 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.28920349 |
44 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.27446545 |
45 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.26351147 |
46 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.25551633 |
47 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.24301881 |
48 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.21317222 |
49 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.19694687 |
50 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.19397349 |
51 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.17180029 |
52 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.13155933 |
53 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.11820195 |
54 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 1.10104668 |
55 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.10007777 |
56 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.07406613 |
57 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.05337710 |
58 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.03489756 |
59 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.02324037 |
60 | Alzheimers disease_Homo sapiens_hsa05010 | 1.01724070 |
61 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.00747326 |
62 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.99672637 |
63 | Axon guidance_Homo sapiens_hsa04360 | 0.98977160 |
64 | Basal transcription factors_Homo sapiens_hsa03022 | 0.98342972 |
65 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.97943949 |
66 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.96532872 |
67 | Parkinsons disease_Homo sapiens_hsa05012 | 0.94675652 |
68 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.94657063 |
69 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.94181123 |
70 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.92122754 |
71 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.91808259 |
72 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.91020792 |
73 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.90892155 |
74 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.90753083 |
75 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.90718103 |
76 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.90060113 |
77 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.89756783 |
78 | Long-term depression_Homo sapiens_hsa04730 | 0.88662996 |
79 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.86589760 |
80 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.86509657 |
81 | Gap junction_Homo sapiens_hsa04540 | 0.85908813 |
82 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.85234056 |
83 | Melanogenesis_Homo sapiens_hsa04916 | 0.85034706 |
84 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.83700582 |
85 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.82081399 |
86 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.81857779 |
87 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.81396849 |
88 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.80034771 |
89 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.79404250 |
90 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.79398260 |
91 | ABC transporters_Homo sapiens_hsa02010 | 0.79023024 |
92 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.77295644 |
93 | Metabolic pathways_Homo sapiens_hsa01100 | 0.76440210 |
94 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.76122045 |
95 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.75728805 |
96 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.75389053 |
97 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.75377982 |
98 | Tight junction_Homo sapiens_hsa04530 | 0.74101632 |
99 | Purine metabolism_Homo sapiens_hsa00230 | 0.73718519 |
100 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.70829073 |
101 | Alcoholism_Homo sapiens_hsa05034 | 0.69976166 |
102 | Ribosome_Homo sapiens_hsa03010 | 0.69733807 |
103 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.69472098 |
104 | Mineral absorption_Homo sapiens_hsa04978 | 0.68968870 |
105 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.68169513 |
106 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.66663987 |
107 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.66558793 |
108 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.64451763 |
109 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.63902614 |
110 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.61877257 |
111 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.61639219 |
112 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.61399890 |
113 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.61118928 |
114 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.59419966 |
115 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.59122294 |
116 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.58730385 |
117 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.56228605 |
118 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.55925757 |
119 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.55434282 |
120 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.54824513 |
121 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.54182256 |
122 | Proteasome_Homo sapiens_hsa03050 | 0.53566529 |
123 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.51264673 |
124 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.50598058 |
125 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.50176295 |
126 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.49981449 |
127 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.49062386 |
128 | Circadian rhythm_Homo sapiens_hsa04710 | 0.48905354 |
129 | Phagosome_Homo sapiens_hsa04145 | 0.47954215 |
130 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.47596197 |
131 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.47187366 |
132 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.45949576 |
133 | RNA polymerase_Homo sapiens_hsa03020 | 0.44687253 |
134 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.42429028 |
135 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.42127301 |
136 | Sulfur relay system_Homo sapiens_hsa04122 | 0.41033920 |
137 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.40937681 |
138 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.38009771 |
139 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.37392098 |
140 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.36958039 |
141 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.36189101 |
142 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.35709957 |
143 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.35204528 |
144 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.33452653 |
145 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.33066416 |
146 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.32880303 |
147 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.32378030 |
148 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.31957783 |
149 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.29384073 |
150 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.27116206 |