

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of natural killer cell differentiation (GO:0032825) | 9.22667692 |
| 2 | positive regulation of interleukin-17 production (GO:0032740) | 7.26361836 |
| 3 | positive regulation of tyrosine phosphorylation of Stat1 protein (GO:0042511) | 7.25422230 |
| 4 | regulation of natural killer cell differentiation (GO:0032823) | 6.27737160 |
| 5 | regulation of tyrosine phosphorylation of Stat1 protein (GO:0042510) | 6.16618262 |
| 6 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 5.65062615 |
| 7 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 5.65062615 |
| 8 | isotype switching (GO:0045190) | 5.65062615 |
| 9 | positive regulation of interferon-gamma biosynthetic process (GO:0045078) | 5.08825512 |
| 10 | somatic recombination of immunoglobulin gene segments (GO:0016447) | 4.81620451 |
| 11 | positive regulation of natural killer cell activation (GO:0032816) | 4.73974403 |
| 12 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 4.63224410 |
| 13 | somatic diversification of immunoglobulins (GO:0016445) | 4.58039913 |
| 14 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 4.55027084 |
| 15 | regulation of mitotic spindle checkpoint (GO:1903504) | 4.50389983 |
| 16 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 4.50389983 |
| 17 | proteasome assembly (GO:0043248) | 4.36738686 |
| 18 | regulation of immunoglobulin secretion (GO:0051023) | 4.31362796 |
| 19 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 4.21706424 |
| 20 | response to pheromone (GO:0019236) | 4.14278444 |
| 21 | positive regulation of interleukin-10 production (GO:0032733) | 4.10810873 |
| 22 | regulation of isotype switching to IgG isotypes (GO:0048302) | 4.04164440 |
| 23 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.95846324 |
| 24 | DNA deamination (GO:0045006) | 3.92217375 |
| 25 | DNA double-strand break processing (GO:0000729) | 3.92088763 |
| 26 | protein K11-linked deubiquitination (GO:0035871) | 3.88359830 |
| 27 | positive regulation of isotype switching (GO:0045830) | 3.84281259 |
| 28 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.78703789 |
| 29 | regulation of interferon-gamma biosynthetic process (GO:0045072) | 3.75511694 |
| 30 | replication fork processing (GO:0031297) | 3.67548155 |
| 31 | cytokine production involved in immune response (GO:0002367) | 3.65091451 |
| 32 | proline transport (GO:0015824) | 3.65073522 |
| 33 | positive regulation of DNA recombination (GO:0045911) | 3.61092140 |
| 34 | positive regulation of endothelial cell apoptotic process (GO:2000353) | 3.61073233 |
| 35 | positive regulation of cell cycle checkpoint (GO:1901978) | 3.58183422 |
| 36 | regulation of chronic inflammatory response (GO:0002676) | 3.56130872 |
| 37 | regulation of natural killer cell activation (GO:0032814) | 3.49976648 |
| 38 | positive regulation of tyrosine phosphorylation of Stat3 protein (GO:0042517) | 3.48351041 |
| 39 | production of molecular mediator of immune response (GO:0002440) | 3.39177586 |
| 40 | regulation of immunoglobulin production (GO:0002637) | 3.31046848 |
| 41 | regulation of interleukin-17 production (GO:0032660) | 3.23811059 |
| 42 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 3.21400097 |
| 43 | regulation of proton transport (GO:0010155) | 3.21170746 |
| 44 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.19118095 |
| 45 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.19118095 |
| 46 | somatic diversification of immune receptors via germline recombination within a single locus (GO:000 | 3.16578117 |
| 47 | somatic cell DNA recombination (GO:0016444) | 3.16578117 |
| 48 | phospholipid homeostasis (GO:0055091) | 3.14820711 |
| 49 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.13840472 |
| 50 | somatic diversification of immune receptors (GO:0002200) | 3.13301257 |
| 51 | positive regulation of chemokine biosynthetic process (GO:0045080) | 3.10770213 |
| 52 | kidney morphogenesis (GO:0060993) | 3.09961519 |
| 53 | nucleotide transmembrane transport (GO:1901679) | 3.06189919 |
| 54 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.99283559 |
| 55 | termination of RNA polymerase III transcription (GO:0006386) | 2.99283559 |
| 56 | positive regulation of interleukin-12 production (GO:0032735) | 2.99071049 |
| 57 | negative regulation of acute inflammatory response (GO:0002674) | 2.98990422 |
| 58 | regulation of MHC class II biosynthetic process (GO:0045346) | 2.98797947 |
| 59 | positive regulation of histone H3-K4 methylation (GO:0051571) | 2.98305239 |
| 60 | GTP biosynthetic process (GO:0006183) | 2.97127329 |
| 61 | regulation of isotype switching (GO:0045191) | 2.96872442 |
| 62 | male meiosis I (GO:0007141) | 2.94975357 |
| 63 | regulation of tyrosine phosphorylation of Stat3 protein (GO:0042516) | 2.94220091 |
| 64 | regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510) | 2.90167164 |
| 65 | regulation of natural killer cell mediated immunity (GO:0002715) | 2.88741562 |
| 66 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 2.88741562 |
| 67 | regulation of mitochondrial translation (GO:0070129) | 2.88407480 |
| 68 | inner mitochondrial membrane organization (GO:0007007) | 2.85795170 |
| 69 | double-strand break repair via homologous recombination (GO:0000724) | 2.83193198 |
| 70 | recombinational repair (GO:0000725) | 2.82878021 |
| 71 | positive regulation of tyrosine phosphorylation of STAT protein (GO:0042531) | 2.81550597 |
| 72 | transcription from mitochondrial promoter (GO:0006390) | 2.80526709 |
| 73 | regulation of hippo signaling (GO:0035330) | 2.79242914 |
| 74 | positive regulation of cell fate commitment (GO:0010455) | 2.78939985 |
| 75 | regulation of DNA recombination (GO:0000018) | 2.73191029 |
| 76 | T-helper cell differentiation (GO:0042093) | 2.72743614 |
| 77 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 2.72743614 |
| 78 | regulation of interleukin-10 production (GO:0032653) | 2.70980498 |
| 79 | rRNA modification (GO:0000154) | 2.70865766 |
| 80 | fucose catabolic process (GO:0019317) | 2.70456976 |
| 81 | L-fucose metabolic process (GO:0042354) | 2.70456976 |
| 82 | L-fucose catabolic process (GO:0042355) | 2.70456976 |
| 83 | exogenous drug catabolic process (GO:0042738) | 2.68910426 |
| 84 | B cell activation involved in immune response (GO:0002312) | 2.67198121 |
| 85 | positive regulation of T cell migration (GO:2000406) | 2.65005645 |
| 86 | regulation of acyl-CoA biosynthetic process (GO:0050812) | 2.64432566 |
| 87 | positive regulation of tissue remodeling (GO:0034105) | 2.64077508 |
| 88 | regulation of cofactor metabolic process (GO:0051193) | 2.63155290 |
| 89 | regulation of coenzyme metabolic process (GO:0051196) | 2.63155290 |
| 90 | regulation of centriole replication (GO:0046599) | 2.62888801 |
| 91 | estrogen biosynthetic process (GO:0006703) | 2.62498281 |
| 92 | pseudouridine synthesis (GO:0001522) | 2.60891659 |
| 93 | synapsis (GO:0007129) | 2.60509964 |
| 94 | positive regulation of immunoglobulin production (GO:0002639) | 2.59146452 |
| 95 | inositol phosphate catabolic process (GO:0071545) | 2.58099150 |
| 96 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 2.57823971 |
| 97 | protein neddylation (GO:0045116) | 2.57706478 |
| 98 | termination of RNA polymerase I transcription (GO:0006363) | 2.55846643 |
| 99 | positive regulation of activated T cell proliferation (GO:0042104) | 2.54118672 |
| 100 | reflex (GO:0060004) | 2.53180097 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 5.80620015 |
| 2 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 3.79530883 |
| 3 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.49613447 |
| 4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.06509836 |
| 5 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.02834451 |
| 6 | VDR_22108803_ChIP-Seq_LS180_Human | 2.85492080 |
| 7 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.77704919 |
| 8 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.68173225 |
| 9 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.63357308 |
| 10 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.60616752 |
| 11 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.54945207 |
| 12 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.44830308 |
| 13 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.44059294 |
| 14 | EWS_26573619_Chip-Seq_HEK293_Human | 2.29442764 |
| 15 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.27800763 |
| 16 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.26052276 |
| 17 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.20571211 |
| 18 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.12823339 |
| 19 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.12074883 |
| 20 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.10975480 |
| 21 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 2.02760415 |
| 22 | TP53_22573176_ChIP-Seq_HFKS_Human | 2.01834576 |
| 23 | P300_19829295_ChIP-Seq_ESCs_Human | 1.98654396 |
| 24 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.94378179 |
| 25 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.89914439 |
| 26 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.75988045 |
| 27 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.70877174 |
| 28 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.67139910 |
| 29 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.64129431 |
| 30 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.62397568 |
| 31 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.59045699 |
| 32 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.54264940 |
| 33 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.52243768 |
| 34 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.50619321 |
| 35 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.46819698 |
| 36 | FUS_26573619_Chip-Seq_HEK293_Human | 1.45818902 |
| 37 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.45633948 |
| 38 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.45633948 |
| 39 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.41445911 |
| 40 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.40135350 |
| 41 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.40135350 |
| 42 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.37054897 |
| 43 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.36485982 |
| 44 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.34342671 |
| 45 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.32632725 |
| 46 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.32120954 |
| 47 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.30293520 |
| 48 | GATA1_22025678_ChIP-Seq_K562_Human | 1.28877668 |
| 49 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.28726819 |
| 50 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.28493619 |
| 51 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.28217063 |
| 52 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.27430279 |
| 53 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.26463791 |
| 54 | STAT3_23295773_ChIP-Seq_U87_Human | 1.25922265 |
| 55 | TCF4_23295773_ChIP-Seq_U87_Human | 1.25296915 |
| 56 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.24915344 |
| 57 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.23856729 |
| 58 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.20639447 |
| 59 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.19179367 |
| 60 | GATA3_26560356_Chip-Seq_TH2_Human | 1.18211138 |
| 61 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.17451909 |
| 62 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.17332295 |
| 63 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.17203143 |
| 64 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.14631832 |
| 65 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.13733328 |
| 66 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.13047878 |
| 67 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.12444219 |
| 68 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.12362002 |
| 69 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.10815979 |
| 70 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.09982204 |
| 71 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.09424700 |
| 72 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.08581241 |
| 73 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.07548956 |
| 74 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 1.07444112 |
| 75 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.07236705 |
| 76 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.06123757 |
| 77 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.05517477 |
| 78 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.05340066 |
| 79 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.05160336 |
| 80 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.04631744 |
| 81 | AR_25329375_ChIP-Seq_VCAP_Human | 1.04486808 |
| 82 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.03960501 |
| 83 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.03679968 |
| 84 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.03679968 |
| 85 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.02522571 |
| 86 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.01945407 |
| 87 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.01690776 |
| 88 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.01051351 |
| 89 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.00449249 |
| 90 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 0.98533552 |
| 91 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.98269213 |
| 92 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.97586169 |
| 93 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.96870570 |
| 94 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.96387195 |
| 95 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.96291318 |
| 96 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.96104891 |
| 97 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.94991965 |
| 98 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.94897878 |
| 99 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 0.93894915 |
| 100 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.92275756 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001348_abnormal_lacrimal_gland | 4.52245033 |
| 2 | MP0000569_abnormal_digit_pigmentation | 4.25265006 |
| 3 | MP0008877_abnormal_DNA_methylation | 3.74815193 |
| 4 | MP0004742_abnormal_vestibular_system | 3.31610356 |
| 5 | MP0008872_abnormal_physiological_respon | 2.99402920 |
| 6 | MP0001873_stomach_inflammation | 2.52595642 |
| 7 | MP0001984_abnormal_olfaction | 2.52295042 |
| 8 | MP0001968_abnormal_touch/_nociception | 2.49567693 |
| 9 | MP0010386_abnormal_urinary_bladder | 2.45289341 |
| 10 | MP0005379_endocrine/exocrine_gland_phen | 2.44221918 |
| 11 | MP0002102_abnormal_ear_morphology | 2.29040711 |
| 12 | MP0002736_abnormal_nociception_after | 2.27355731 |
| 13 | MP0002837_dystrophic_cardiac_calcinosis | 2.24508117 |
| 14 | MP0006082_CNS_inflammation | 2.01578091 |
| 15 | MP0008875_abnormal_xenobiotic_pharmacok | 1.97562880 |
| 16 | MP0005408_hypopigmentation | 1.96655103 |
| 17 | MP0003195_calcinosis | 1.93298369 |
| 18 | MP0003787_abnormal_imprinting | 1.93070642 |
| 19 | MP0002254_reproductive_system_inflammat | 1.92914168 |
| 20 | MP0010234_abnormal_vibrissa_follicle | 1.90730824 |
| 21 | MP0005174_abnormal_tail_pigmentation | 1.88348590 |
| 22 | MP0003890_abnormal_embryonic-extraembry | 1.87609898 |
| 23 | MP0001835_abnormal_antigen_presentation | 1.87289000 |
| 24 | MP0005310_abnormal_salivary_gland | 1.86015434 |
| 25 | MP0008057_abnormal_DNA_replication | 1.78954546 |
| 26 | MP0005645_abnormal_hypothalamus_physiol | 1.64328038 |
| 27 | MP0003329_amyloid_beta_deposits | 1.64106238 |
| 28 | MP0005551_abnormal_eye_electrophysiolog | 1.54914362 |
| 29 | MP0002876_abnormal_thyroid_physiology | 1.52825487 |
| 30 | MP0002163_abnormal_gland_morphology | 1.52396996 |
| 31 | MP0006072_abnormal_retinal_apoptosis | 1.49637890 |
| 32 | MP0003646_muscle_fatigue | 1.46934113 |
| 33 | MP0002009_preneoplasia | 1.45774735 |
| 34 | MP0000427_abnormal_hair_cycle | 1.44080484 |
| 35 | MP0009745_abnormal_behavioral_response | 1.41017857 |
| 36 | MP0008789_abnormal_olfactory_epithelium | 1.35208885 |
| 37 | MP0009840_abnormal_foam_cell | 1.34819945 |
| 38 | MP0003045_fibrosis | 1.33745500 |
| 39 | MP0005075_abnormal_melanosome_morpholog | 1.31749964 |
| 40 | MP0000685_abnormal_immune_system | 1.31040402 |
| 41 | MP0003693_abnormal_embryo_hatching | 1.30317997 |
| 42 | MP0000372_irregular_coat_pigmentation | 1.29042429 |
| 43 | MP0002928_abnormal_bile_duct | 1.27107040 |
| 44 | MP0000538_abnormal_urinary_bladder | 1.25540144 |
| 45 | MP0002166_altered_tumor_susceptibility | 1.22190240 |
| 46 | MP0003943_abnormal_hepatobiliary_system | 1.20041714 |
| 47 | MP0003567_abnormal_fetal_cardiomyocyte | 1.16567254 |
| 48 | MP0008775_abnormal_heart_ventricle | 1.16424266 |
| 49 | MP0004133_heterotaxia | 1.16034041 |
| 50 | MP0001501_abnormal_sleep_pattern | 1.13613002 |
| 51 | MP0010678_abnormal_skin_adnexa | 1.12227761 |
| 52 | MP0000604_amyloidosis | 1.11940447 |
| 53 | MP0001986_abnormal_taste_sensitivity | 1.10595823 |
| 54 | MP0004215_abnormal_myocardial_fiber | 1.10218615 |
| 55 | MP0010329_abnormal_lipoprotein_level | 1.09231286 |
| 56 | MP0005167_abnormal_blood-brain_barrier | 1.06654404 |
| 57 | MP0003786_premature_aging | 1.04977650 |
| 58 | MP0002638_abnormal_pupillary_reflex | 1.02850483 |
| 59 | MP0004381_abnormal_hair_follicle | 1.01908842 |
| 60 | MP0000015_abnormal_ear_pigmentation | 1.01384279 |
| 61 | MP0001529_abnormal_vocalization | 1.01130669 |
| 62 | MP0001486_abnormal_startle_reflex | 0.99503901 |
| 63 | MP0005387_immune_system_phenotype | 0.98210962 |
| 64 | MP0001790_abnormal_immune_system | 0.98210962 |
| 65 | MP0005410_abnormal_fertilization | 0.97243542 |
| 66 | MP0002735_abnormal_chemical_nociception | 0.94564518 |
| 67 | MP0002006_tumorigenesis | 0.93722839 |
| 68 | MP0002138_abnormal_hepatobiliary_system | 0.92988121 |
| 69 | MP0005253_abnormal_eye_physiology | 0.88558931 |
| 70 | MP0002229_neurodegeneration | 0.88399361 |
| 71 | MP0003136_yellow_coat_color | 0.85321521 |
| 72 | MP0005389_reproductive_system_phenotype | 0.83854566 |
| 73 | MP0003718_maternal_effect | 0.82769216 |
| 74 | MP0000383_abnormal_hair_follicle | 0.82726770 |
| 75 | MP0001919_abnormal_reproductive_system | 0.82320798 |
| 76 | MP0003937_abnormal_limbs/digits/tail_de | 0.81992144 |
| 77 | MP0002693_abnormal_pancreas_physiology | 0.79255957 |
| 78 | MP0008007_abnormal_cellular_replicative | 0.78216965 |
| 79 | MP0005084_abnormal_gallbladder_morpholo | 0.77908616 |
| 80 | MP0001485_abnormal_pinna_reflex | 0.74861812 |
| 81 | MP0002272_abnormal_nervous_system | 0.74420483 |
| 82 | MP0000631_abnormal_neuroendocrine_gland | 0.74267101 |
| 83 | MP0001905_abnormal_dopamine_level | 0.71743892 |
| 84 | MP0006036_abnormal_mitochondrial_physio | 0.71621946 |
| 85 | MP0003936_abnormal_reproductive_system | 0.70828820 |
| 86 | MP0003633_abnormal_nervous_system | 0.69970677 |
| 87 | MP0005636_abnormal_mineral_homeostasis | 0.68924401 |
| 88 | MP0002332_abnormal_exercise_endurance | 0.65494382 |
| 89 | MP0008058_abnormal_DNA_repair | 0.64669303 |
| 90 | MP0004043_abnormal_pH_regulation | 0.64487864 |
| 91 | MP0002168_other_aberrant_phenotype | 0.64482988 |
| 92 | MP0005671_abnormal_response_to | 0.63452419 |
| 93 | MP0001661_extended_life_span | 0.62378216 |
| 94 | MP0001188_hyperpigmentation | 0.62183088 |
| 95 | MP0001243_abnormal_dermal_layer | 0.62166837 |
| 96 | MP0000639_abnormal_adrenal_gland | 0.61244952 |
| 97 | MP0005367_renal/urinary_system_phenotyp | 0.60995149 |
| 98 | MP0000516_abnormal_urinary_system | 0.60995149 |
| 99 | MP0004019_abnormal_vitamin_homeostasis | 0.60247253 |
| 100 | MP0002184_abnormal_innervation | 0.60110786 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Stomatitis (HP:0010280) | 7.38836715 |
| 2 | Chronic diarrhea (HP:0002028) | 6.02085409 |
| 3 | Increased IgM level (HP:0003496) | 5.15381070 |
| 4 | Abnormality of incisor morphology (HP:0011063) | 4.71142130 |
| 5 | Gaze-evoked nystagmus (HP:0000640) | 3.43787562 |
| 6 | IgA deficiency (HP:0002720) | 3.43756694 |
| 7 | Thyroiditis (HP:0100646) | 3.41328152 |
| 8 | Abdominal situs inversus (HP:0003363) | 3.24772626 |
| 9 | Abnormality of abdominal situs (HP:0011620) | 3.24772626 |
| 10 | Multiple enchondromatosis (HP:0005701) | 3.04732710 |
| 11 | Curly hair (HP:0002212) | 2.95359919 |
| 12 | Bilateral sensorineural hearing impairment (HP:0008619) | 2.75935780 |
| 13 | Intestinal atresia (HP:0011100) | 2.70927972 |
| 14 | Inflammation of the large intestine (HP:0002037) | 2.58490763 |
| 15 | Abnormality of the nasal septum (HP:0000419) | 2.58273803 |
| 16 | Progressive macrocephaly (HP:0004481) | 2.55987740 |
| 17 | Progressive inability to walk (HP:0002505) | 2.54367103 |
| 18 | IgG deficiency (HP:0004315) | 2.53348600 |
| 19 | Pancreatic cysts (HP:0001737) | 2.49444723 |
| 20 | Hematochezia (HP:0002573) | 2.48993258 |
| 21 | Abnormality of T cell physiology (HP:0011840) | 2.45222117 |
| 22 | Asplenia (HP:0001746) | 2.43346425 |
| 23 | Fatigue (HP:0012378) | 2.42954838 |
| 24 | Absent hand (HP:0004050) | 2.42031792 |
| 25 | Volvulus (HP:0002580) | 2.41076660 |
| 26 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.35678702 |
| 27 | Hypoplasia of the fovea (HP:0007750) | 2.35678702 |
| 28 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.34974056 |
| 29 | Aqueductal stenosis (HP:0002410) | 2.34630681 |
| 30 | Abnormality of the incisor (HP:0000676) | 2.34586566 |
| 31 | Nephronophthisis (HP:0000090) | 2.31616033 |
| 32 | Acute necrotizing encephalopathy (HP:0006965) | 2.28490018 |
| 33 | Dysmetric saccades (HP:0000641) | 2.26306939 |
| 34 | Abnormal pupillary function (HP:0007686) | 2.26150944 |
| 35 | Gastrointestinal inflammation (HP:0004386) | 2.24482707 |
| 36 | Congenital stationary night blindness (HP:0007642) | 2.21596999 |
| 37 | True hermaphroditism (HP:0010459) | 2.21186026 |
| 38 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.16987432 |
| 39 | Abnormality of T cells (HP:0002843) | 2.12760406 |
| 40 | Renal cortical cysts (HP:0000803) | 2.12644386 |
| 41 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.07434530 |
| 42 | Megalencephaly (HP:0001355) | 2.03931618 |
| 43 | Progressive microcephaly (HP:0000253) | 1.99631410 |
| 44 | Aplasia/Hypoplasia of the macula (HP:0008059) | 1.98970073 |
| 45 | Abnormality of methionine metabolism (HP:0010901) | 1.98793425 |
| 46 | Abnormal albumin level (HP:0012116) | 1.96987233 |
| 47 | Hypoalbuminemia (HP:0003073) | 1.96987233 |
| 48 | Neutropenia (HP:0001875) | 1.96748953 |
| 49 | Delayed puberty (HP:0000823) | 1.96472246 |
| 50 | Type II lissencephaly (HP:0007260) | 1.94181307 |
| 51 | Chin dimple (HP:0010751) | 1.93542113 |
| 52 | Abnormality of vitamin B metabolism (HP:0004340) | 1.92459115 |
| 53 | Abnormality of B cell number (HP:0010975) | 1.90651883 |
| 54 | Cubitus valgus (HP:0002967) | 1.90299935 |
| 55 | Methylmalonic aciduria (HP:0012120) | 1.90184755 |
| 56 | Dyskinesia (HP:0100660) | 1.89848472 |
| 57 | Sclerocornea (HP:0000647) | 1.89794174 |
| 58 | Acute encephalopathy (HP:0006846) | 1.89577550 |
| 59 | Abnormality of the renal medulla (HP:0100957) | 1.87926834 |
| 60 | Pancreatic fibrosis (HP:0100732) | 1.87824638 |
| 61 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.87277085 |
| 62 | Abnormality of midbrain morphology (HP:0002418) | 1.86280581 |
| 63 | Molar tooth sign on MRI (HP:0002419) | 1.86280581 |
| 64 | Attenuation of retinal blood vessels (HP:0007843) | 1.86227882 |
| 65 | Abnormality of the ileum (HP:0001549) | 1.86106634 |
| 66 | B lymphocytopenia (HP:0010976) | 1.85449850 |
| 67 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 1.84079025 |
| 68 | Aplasia/Hypoplasia affecting the retina (HP:0008061) | 1.83934878 |
| 69 | Concave nail (HP:0001598) | 1.83019100 |
| 70 | Abnormality of the parathyroid morphology (HP:0011766) | 1.82811301 |
| 71 | Methylmalonic acidemia (HP:0002912) | 1.81989079 |
| 72 | Medial flaring of the eyebrow (HP:0010747) | 1.81882502 |
| 73 | Optic disc pallor (HP:0000543) | 1.81262990 |
| 74 | Severe combined immunodeficiency (HP:0004430) | 1.81006467 |
| 75 | Abnormality of the renal cortex (HP:0011035) | 1.80647810 |
| 76 | Meckel diverticulum (HP:0002245) | 1.78681461 |
| 77 | Poor head control (HP:0002421) | 1.78512769 |
| 78 | Hypobetalipoproteinemia (HP:0003563) | 1.78424852 |
| 79 | Cerebral hemorrhage (HP:0001342) | 1.77706351 |
| 80 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.76080874 |
| 81 | Increased CSF lactate (HP:0002490) | 1.74456748 |
| 82 | Polydipsia (HP:0001959) | 1.74056350 |
| 83 | Abnormal drinking behavior (HP:0030082) | 1.74056350 |
| 84 | Abnormality of the fovea (HP:0000493) | 1.73977415 |
| 85 | Neoplasm of the adrenal cortex (HP:0100641) | 1.73747006 |
| 86 | Hydroxyprolinuria (HP:0003080) | 1.72621566 |
| 87 | Abnormality of proline metabolism (HP:0010907) | 1.72621566 |
| 88 | Colon cancer (HP:0003003) | 1.72129454 |
| 89 | Chronic hepatic failure (HP:0100626) | 1.72092624 |
| 90 | Large for gestational age (HP:0001520) | 1.70163903 |
| 91 | Scrotal hypoplasia (HP:0000046) | 1.69868185 |
| 92 | Increased serum pyruvate (HP:0003542) | 1.68692312 |
| 93 | Small hand (HP:0200055) | 1.68347023 |
| 94 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.66739308 |
| 95 | Male pseudohermaphroditism (HP:0000037) | 1.66596031 |
| 96 | Gonadal dysgenesis (HP:0000133) | 1.66545345 |
| 97 | Short chin (HP:0000331) | 1.65801247 |
| 98 | Central scotoma (HP:0000603) | 1.65374429 |
| 99 | Limb dystonia (HP:0002451) | 1.64015879 |
| 100 | Congenital sensorineural hearing impairment (HP:0008527) | 1.63082094 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FRK | 6.33906563 |
| 2 | EIF2AK3 | 3.93088524 |
| 3 | MST4 | 3.11456509 |
| 4 | PAK3 | 2.85011623 |
| 5 | PAK6 | 2.64558525 |
| 6 | PDK2 | 2.56637665 |
| 7 | PBK | 2.51707937 |
| 8 | MKNK2 | 2.42990581 |
| 9 | WNK3 | 2.30997427 |
| 10 | FGFR2 | 2.04585900 |
| 11 | KSR1 | 2.04535443 |
| 12 | BMPR1B | 1.94205439 |
| 13 | BRSK2 | 1.86988028 |
| 14 | TSSK6 | 1.84139028 |
| 15 | PLK4 | 1.82502341 |
| 16 | TRIM28 | 1.81249840 |
| 17 | MAP3K4 | 1.74617627 |
| 18 | STK39 | 1.72522269 |
| 19 | CAMKK2 | 1.71860557 |
| 20 | ADRBK2 | 1.66081376 |
| 21 | ACVR1B | 1.62030958 |
| 22 | KSR2 | 1.60320691 |
| 23 | PINK1 | 1.57613968 |
| 24 | EIF2AK1 | 1.54356107 |
| 25 | OXSR1 | 1.48016984 |
| 26 | PNCK | 1.43220027 |
| 27 | PLK3 | 1.41903491 |
| 28 | GRK1 | 1.41585196 |
| 29 | RAF1 | 1.37000760 |
| 30 | BRD4 | 1.33392733 |
| 31 | NEK1 | 1.33225233 |
| 32 | MKNK1 | 1.26862231 |
| 33 | MAP2K7 | 1.20075460 |
| 34 | NLK | 1.19609724 |
| 35 | FGFR1 | 1.17488479 |
| 36 | CSNK1G1 | 1.15235879 |
| 37 | NME1 | 1.14428776 |
| 38 | PRKAA2 | 1.10082514 |
| 39 | CASK | 1.06100961 |
| 40 | ZAK | 1.04886887 |
| 41 | STK16 | 0.97140274 |
| 42 | PHKG2 | 0.95609433 |
| 43 | PHKG1 | 0.95609433 |
| 44 | WNK4 | 0.92616209 |
| 45 | BCR | 0.85287584 |
| 46 | ERBB3 | 0.81065176 |
| 47 | AKT3 | 0.78934657 |
| 48 | ERBB4 | 0.78640705 |
| 49 | EIF2AK2 | 0.75948335 |
| 50 | CSNK1G3 | 0.72016790 |
| 51 | TNK2 | 0.71339732 |
| 52 | TRPM7 | 0.70093771 |
| 53 | SIK3 | 0.68795653 |
| 54 | STK4 | 0.67017506 |
| 55 | CSNK1A1L | 0.63806790 |
| 56 | PLK2 | 0.62918491 |
| 57 | MAPK13 | 0.62261413 |
| 58 | RPS6KA4 | 0.62045881 |
| 59 | MAPK11 | 0.60387451 |
| 60 | IKBKB | 0.59175343 |
| 61 | PRKCG | 0.58611023 |
| 62 | VRK1 | 0.58372933 |
| 63 | PRKCE | 0.57508623 |
| 64 | BMPR2 | 0.54165139 |
| 65 | CSNK1G2 | 0.52345980 |
| 66 | TTK | 0.50977923 |
| 67 | CSNK1A1 | 0.50386450 |
| 68 | WEE1 | 0.50159510 |
| 69 | NUAK1 | 0.49574744 |
| 70 | MAP4K2 | 0.49093238 |
| 71 | FGFR3 | 0.45713123 |
| 72 | NEK6 | 0.45426567 |
| 73 | ADRBK1 | 0.43966854 |
| 74 | MAP2K1 | 0.43174067 |
| 75 | CHUK | 0.41272798 |
| 76 | PLK1 | 0.38167671 |
| 77 | DAPK2 | 0.38090638 |
| 78 | STK3 | 0.37378115 |
| 79 | TEC | 0.37086932 |
| 80 | CDK3 | 0.37016283 |
| 81 | CSNK1D | 0.36491743 |
| 82 | SGK1 | 0.34992116 |
| 83 | TGFBR1 | 0.34916384 |
| 84 | CLK1 | 0.32627783 |
| 85 | INSRR | 0.32341116 |
| 86 | ALK | 0.31623019 |
| 87 | SCYL2 | 0.30772356 |
| 88 | PRKCZ | 0.30719415 |
| 89 | DYRK2 | 0.30058537 |
| 90 | CAMK2D | 0.29061510 |
| 91 | PRKCI | 0.27566914 |
| 92 | PTK2B | 0.27287685 |
| 93 | IGF1R | 0.27038719 |
| 94 | PRKCB | 0.26365544 |
| 95 | PRKG1 | 0.25589195 |
| 96 | CAMK4 | 0.25229938 |
| 97 | ATM | 0.25140363 |
| 98 | MAP3K12 | 0.24618654 |
| 99 | JAK1 | 0.24579720 |
| 100 | CHEK1 | 0.24180592 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 5.86784651 |
| 2 | Asthma_Homo sapiens_hsa05310 | 3.14183755 |
| 3 | Proteasome_Homo sapiens_hsa03050 | 2.86521736 |
| 4 | Allograft rejection_Homo sapiens_hsa05330 | 2.61477229 |
| 5 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.57087053 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.46326203 |
| 7 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.37082683 |
| 8 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.36938828 |
| 9 | Protein export_Homo sapiens_hsa03060 | 2.31474421 |
| 10 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.31087119 |
| 11 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.29364767 |
| 12 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.26529810 |
| 13 | Homologous recombination_Homo sapiens_hsa03440 | 2.21511251 |
| 14 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.03983585 |
| 15 | Phototransduction_Homo sapiens_hsa04744 | 1.97142594 |
| 16 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.96905390 |
| 17 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.94234267 |
| 18 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.78643345 |
| 19 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.75531386 |
| 20 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.69744119 |
| 21 | RNA transport_Homo sapiens_hsa03013 | 1.55911034 |
| 22 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.51589408 |
| 23 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.45590965 |
| 24 | RNA degradation_Homo sapiens_hsa03018 | 1.42249784 |
| 25 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.40155175 |
| 26 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.39167909 |
| 27 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.28840839 |
| 28 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.27408578 |
| 29 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.24420589 |
| 30 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.23904195 |
| 31 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.21968226 |
| 32 | Parkinsons disease_Homo sapiens_hsa05012 | 1.20930780 |
| 33 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.19738036 |
| 34 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.13198962 |
| 35 | Taste transduction_Homo sapiens_hsa04742 | 1.11903329 |
| 36 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.10928108 |
| 37 | Basal transcription factors_Homo sapiens_hsa03022 | 1.10731729 |
| 38 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.09113932 |
| 39 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.03259105 |
| 40 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.02269943 |
| 41 | Peroxisome_Homo sapiens_hsa04146 | 1.01804947 |
| 42 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.01124994 |
| 43 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.94996050 |
| 44 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.93761572 |
| 45 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.93043279 |
| 46 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.92570389 |
| 47 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.91731811 |
| 48 | Circadian rhythm_Homo sapiens_hsa04710 | 0.89122343 |
| 49 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.87608508 |
| 50 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.83785586 |
| 51 | Mineral absorption_Homo sapiens_hsa04978 | 0.81865288 |
| 52 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.77464694 |
| 53 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.76407568 |
| 54 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.73318609 |
| 55 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.68089429 |
| 56 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.67780295 |
| 57 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.67083802 |
| 58 | Retinol metabolism_Homo sapiens_hsa00830 | 0.66969454 |
| 59 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.63406478 |
| 60 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.61299155 |
| 61 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.60771361 |
| 62 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.60573009 |
| 63 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.60509339 |
| 64 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.59999925 |
| 65 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.57466487 |
| 66 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.55952225 |
| 67 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.55901480 |
| 68 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.54638810 |
| 69 | Spliceosome_Homo sapiens_hsa03040 | 0.54398923 |
| 70 | Purine metabolism_Homo sapiens_hsa00230 | 0.53549160 |
| 71 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.50618217 |
| 72 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.50518188 |
| 73 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.50082602 |
| 74 | Metabolic pathways_Homo sapiens_hsa01100 | 0.49053484 |
| 75 | Alzheimers disease_Homo sapiens_hsa05010 | 0.48833252 |
| 76 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.48330471 |
| 77 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.47230283 |
| 78 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.46501751 |
| 79 | Huntingtons disease_Homo sapiens_hsa05016 | 0.46489691 |
| 80 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.45161318 |
| 81 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.43667959 |
| 82 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.43505113 |
| 83 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.43246050 |
| 84 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.43207522 |
| 85 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.41750928 |
| 86 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.39683262 |
| 87 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.39150249 |
| 88 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.38824170 |
| 89 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.37090424 |
| 90 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.36121833 |
| 91 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.35017247 |
| 92 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.33434980 |
| 93 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.32622787 |
| 94 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.32466310 |
| 95 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.30994428 |
| 96 | Legionellosis_Homo sapiens_hsa05134 | 0.30294185 |
| 97 | Nicotine addiction_Homo sapiens_hsa05033 | 0.29662000 |
| 98 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.29480339 |
| 99 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.29305009 |
| 100 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.24972233 |

