

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | cellular extravasation (GO:0045123) | 5.45403291 |
| 2 | positive regulation by symbiont of host defense response (GO:0052509) | 5.18189947 |
| 3 | modulation by symbiont of host defense response (GO:0052031) | 5.18189947 |
| 4 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 5.18189947 |
| 5 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 5.18189947 |
| 6 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 5.18189947 |
| 7 | modulation by symbiont of host immune response (GO:0052553) | 5.18189947 |
| 8 | negative regulation of cell killing (GO:0031342) | 5.12440965 |
| 9 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.12440965 |
| 10 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.08512738 |
| 11 | detection of other organism (GO:0098543) | 5.07432705 |
| 12 | detection of bacterium (GO:0016045) | 4.96138169 |
| 13 | neutrophil activation involved in immune response (GO:0002283) | 4.85182469 |
| 14 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.70543434 |
| 15 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.62661015 |
| 16 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.57217524 |
| 17 | detection of external biotic stimulus (GO:0098581) | 4.50810284 |
| 18 | macrophage activation involved in immune response (GO:0002281) | 4.41486644 |
| 19 | disruption of cells of other organism involved in symbiotic interaction (GO:0051818) | 4.35343595 |
| 20 | killing of cells in other organism involved in symbiotic interaction (GO:0051883) | 4.35343595 |
| 21 | detection of molecule of bacterial origin (GO:0032490) | 4.33831798 |
| 22 | leukocyte migration involved in inflammatory response (GO:0002523) | 4.31031647 |
| 23 | neutrophil mediated immunity (GO:0002446) | 4.26318866 |
| 24 | response to peptidoglycan (GO:0032494) | 4.21693276 |
| 25 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.16232639 |
| 26 | microglial cell activation (GO:0001774) | 4.12038102 |
| 27 | detection of biotic stimulus (GO:0009595) | 3.96523186 |
| 28 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.87615412 |
| 29 | leukocyte aggregation (GO:0070486) | 3.81233772 |
| 30 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.78776881 |
| 31 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.78672082 |
| 32 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 3.76885526 |
| 33 | respiratory burst (GO:0045730) | 3.70164653 |
| 34 | neutrophil activation (GO:0042119) | 3.66151948 |
| 35 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.64198479 |
| 36 | response to host immune response (GO:0052572) | 3.64198479 |
| 37 | macrophage activation (GO:0042116) | 3.61256108 |
| 38 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.59978347 |
| 39 | regulation of gamma-delta T cell activation (GO:0046643) | 3.53753948 |
| 40 | complement activation, alternative pathway (GO:0006957) | 3.51785171 |
| 41 | immunoglobulin mediated immune response (GO:0016064) | 3.45456575 |
| 42 | negative regulation of interleukin-12 production (GO:0032695) | 3.44522386 |
| 43 | negative regulation of fibrinolysis (GO:0051918) | 3.44333955 |
| 44 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 3.42020546 |
| 45 | myeloid leukocyte mediated immunity (GO:0002444) | 3.39768476 |
| 46 | regulation of fibrinolysis (GO:0051917) | 3.35912380 |
| 47 | regulation of triglyceride catabolic process (GO:0010896) | 3.33555534 |
| 48 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.31481294 |
| 49 | response to host (GO:0075136) | 3.31481294 |
| 50 | response to host defenses (GO:0052200) | 3.31481294 |
| 51 | phospholipid efflux (GO:0033700) | 3.30587783 |
| 52 | granulocyte activation (GO:0036230) | 3.30366195 |
| 53 | response to interleukin-15 (GO:0070672) | 3.28229522 |
| 54 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.27501343 |
| 55 | regulation of mast cell degranulation (GO:0043304) | 3.27221227 |
| 56 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.25987547 |
| 57 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 3.24060399 |
| 58 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.16449391 |
| 59 | myeloid cell activation involved in immune response (GO:0002275) | 3.13014662 |
| 60 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.11927529 |
| 61 | germinal center formation (GO:0002467) | 3.08071775 |
| 62 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.06442191 |
| 63 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 3.06380100 |
| 64 | negative regulation of phagocytosis (GO:0050765) | 3.02089550 |
| 65 | regulation of protein activation cascade (GO:2000257) | 3.00498893 |
| 66 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 2.96905535 |
| 67 | regulation of mast cell activation involved in immune response (GO:0033006) | 2.96665048 |
| 68 | regulation of leukocyte degranulation (GO:0043300) | 2.96064900 |
| 69 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 2.94859687 |
| 70 | regulation of complement activation (GO:0030449) | 2.94788919 |
| 71 | positive regulation of mast cell activation (GO:0033005) | 2.93279832 |
| 72 | positive regulation of lipoprotein lipase activity (GO:0051006) | 2.90614544 |
| 73 | positive regulation of triglyceride lipase activity (GO:0061365) | 2.90614544 |
| 74 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 2.89632229 |
| 75 | regulation of interleukin-8 biosynthetic process (GO:0045414) | 2.89558285 |
| 76 | B cell receptor signaling pathway (GO:0050853) | 2.87916805 |
| 77 | epoxygenase P450 pathway (GO:0019373) | 2.83008488 |
| 78 | cellular response to interleukin-15 (GO:0071350) | 2.82912725 |
| 79 | negative regulation of B cell mediated immunity (GO:0002713) | 2.81880161 |
| 80 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 2.81880161 |
| 81 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.80719205 |
| 82 | negative regulation of cytokine production involved in immune response (GO:0002719) | 2.79709181 |
| 83 | positive regulation of cellular amide metabolic process (GO:0034250) | 2.79047769 |
| 84 | cellular response to type I interferon (GO:0071357) | 2.78548900 |
| 85 | type I interferon signaling pathway (GO:0060337) | 2.78548900 |
| 86 | response to type I interferon (GO:0034340) | 2.78018962 |
| 87 | drug catabolic process (GO:0042737) | 2.76540732 |
| 88 | positive regulation of B cell differentiation (GO:0045579) | 2.76233885 |
| 89 | regulation of B cell differentiation (GO:0045577) | 2.72044262 |
| 90 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 2.71793483 |
| 91 | regulation of mast cell activation (GO:0033003) | 2.71680393 |
| 92 | exogenous drug catabolic process (GO:0042738) | 2.69718832 |
| 93 | negative regulation of interleukin-8 production (GO:0032717) | 2.68874808 |
| 94 | negative regulation of T cell mediated immunity (GO:0002710) | 2.68500041 |
| 95 | B cell mediated immunity (GO:0019724) | 2.67772717 |
| 96 | leukocyte degranulation (GO:0043299) | 2.66893124 |
| 97 | regulation of T-helper 2 cell differentiation (GO:0045628) | 2.66853718 |
| 98 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.66281799 |
| 99 | defense response to protozoan (GO:0042832) | 2.65193722 |
| 100 | negative regulation of innate immune response (GO:0045824) | 2.64777496 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.78221216 |
| 2 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.97726134 |
| 3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.50406592 |
| 4 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.13213498 |
| 5 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 3.11353042 |
| 6 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.94192201 |
| 7 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.84142197 |
| 8 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.67050657 |
| 9 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.59205258 |
| 10 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.58739683 |
| 11 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.57489246 |
| 12 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.47039261 |
| 13 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.45862774 |
| 14 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 2.43535624 |
| 15 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.38793605 |
| 16 | * SPI1_23547873_ChIP-Seq_NB4_Human | 2.32623263 |
| 17 | SPI1_23127762_ChIP-Seq_K562_Human | 2.31182294 |
| 18 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.29620824 |
| 19 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 2.28269438 |
| 20 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 2.26369082 |
| 21 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.24970485 |
| 22 | * E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.10088935 |
| 23 | MAF_26560356_Chip-Seq_TH1_Human | 2.09623252 |
| 24 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 2.07655791 |
| 25 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.03994987 |
| 26 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 2.01074940 |
| 27 | MYC_22102868_ChIP-Seq_BL_Human | 1.98008345 |
| 28 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.95200945 |
| 29 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.93499547 |
| 30 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.93321199 |
| 31 | UTX_26944678_Chip-Seq_JUKART_Human | 1.91995229 |
| 32 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.91831546 |
| 33 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.89171489 |
| 34 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.88596709 |
| 35 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.87817675 |
| 36 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 1.84904545 |
| 37 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.84463287 |
| 38 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.83122860 |
| 39 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.82331404 |
| 40 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.81705051 |
| 41 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.79523449 |
| 42 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.76472228 |
| 43 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.69415762 |
| 44 | MYB_26560356_Chip-Seq_TH2_Human | 1.68850726 |
| 45 | MYB_26560356_Chip-Seq_TH1_Human | 1.66059466 |
| 46 | MAF_26560356_Chip-Seq_TH2_Human | 1.64918899 |
| 47 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.64776484 |
| 48 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.63852486 |
| 49 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.60688805 |
| 50 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.60168459 |
| 51 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.58252997 |
| 52 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.55423211 |
| 53 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.54735427 |
| 54 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.54044439 |
| 55 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.52645353 |
| 56 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.50655998 |
| 57 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.47778336 |
| 58 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.45632635 |
| 59 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.43604346 |
| 60 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.41301397 |
| 61 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.37769758 |
| 62 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.37567701 |
| 63 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.37083540 |
| 64 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.33556205 |
| 65 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.32512074 |
| 66 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.30508625 |
| 67 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.29506048 |
| 68 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.28247250 |
| 69 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.28199654 |
| 70 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.27867986 |
| 71 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.26506211 |
| 72 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.24750225 |
| 73 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.22996772 |
| 74 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.22549135 |
| 75 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.19668674 |
| 76 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.19504143 |
| 77 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.18203565 |
| 78 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.15331744 |
| 79 | GATA1_19941826_ChIP-Seq_K562_Human | 1.14250637 |
| 80 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.11695050 |
| 81 | GATA1_22025678_ChIP-Seq_K562_Human | 1.10921813 |
| 82 | * SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.09359380 |
| 83 | * GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.09232897 |
| 84 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.09039670 |
| 85 | SPI1_20517297_ChIP-Seq_HL60_Human | 1.07321766 |
| 86 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.07148402 |
| 87 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.06359366 |
| 88 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.06002454 |
| 89 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.04835709 |
| 90 | P68_20966046_ChIP-Seq_HELA_Human | 1.04120477 |
| 91 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.02760981 |
| 92 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.01710098 |
| 93 | GATA3_26560356_Chip-Seq_TH2_Human | 1.01640092 |
| 94 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 1.00908626 |
| 95 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.00744513 |
| 96 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 0.99972245 |
| 97 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.98582579 |
| 98 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 0.97647010 |
| 99 | RACK7_27058665_Chip-Seq_MCF-7_Human | 0.94285077 |
| 100 | SMC4_20622854_ChIP-Seq_HELA_Human | 0.90807205 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003724_increased_susceptibility_to | 4.08856166 |
| 2 | MP0003436_decreased_susceptibility_to | 4.03573477 |
| 3 | MP0003303_peritoneal_inflammation | 3.61436999 |
| 4 | MP0002139_abnormal_hepatobiliary_system | 3.19210239 |
| 5 | MP0005360_urolithiasis | 3.05951557 |
| 6 | MP0002419_abnormal_innate_immunity | 2.98664258 |
| 7 | MP0001835_abnormal_antigen_presentation | 2.90972545 |
| 8 | MP0003191_abnormal_cellular_cholesterol | 2.78321677 |
| 9 | MP0009785_altered_susceptibility_to | 2.76510633 |
| 10 | MP0005025_abnormal_response_to | 2.67610903 |
| 11 | MP0005085_abnormal_gallbladder_physiolo | 2.60925335 |
| 12 | MP0000685_abnormal_immune_system | 2.46526874 |
| 13 | MP0002132_abnormal_respiratory_system | 2.43137399 |
| 14 | MP0001800_abnormal_humoral_immune | 2.42616807 |
| 15 | MP0001790_abnormal_immune_system | 2.42499006 |
| 16 | MP0005387_immune_system_phenotype | 2.42499006 |
| 17 | MP0005000_abnormal_immune_tolerance | 2.36452887 |
| 18 | MP0005365_abnormal_bile_salt | 2.31769725 |
| 19 | MP0005464_abnormal_platelet_physiology | 2.28676012 |
| 20 | MP0005671_abnormal_response_to | 2.27292703 |
| 21 | MP0003195_calcinosis | 2.19565076 |
| 22 | MP0006082_CNS_inflammation | 2.13362083 |
| 23 | MP0002723_abnormal_immune_serum | 2.13355285 |
| 24 | MP0003172_abnormal_lysosome_physiology | 2.12102526 |
| 25 | MP0002420_abnormal_adaptive_immunity | 2.06205903 |
| 26 | MP0001819_abnormal_immune_cell | 2.03852378 |
| 27 | MP0001533_abnormal_skeleton_physiology | 2.03162423 |
| 28 | MP0002452_abnormal_antigen_presenting | 2.02427737 |
| 29 | MP0005451_abnormal_body_composition | 1.98253240 |
| 30 | MP0002138_abnormal_hepatobiliary_system | 1.91113425 |
| 31 | MP0002148_abnormal_hypersensitivity_rea | 1.85153028 |
| 32 | MP0003183_abnormal_peptide_metabolism | 1.83830114 |
| 33 | MP0003300_gastrointestinal_ulcer | 1.80672964 |
| 34 | MP0010155_abnormal_intestine_physiology | 1.71000771 |
| 35 | MP0003252_abnormal_bile_duct | 1.69766037 |
| 36 | MP0001845_abnormal_inflammatory_respons | 1.67931380 |
| 37 | MP0002405_respiratory_system_inflammati | 1.67157095 |
| 38 | MP0009278_abnormal_bone_marrow | 1.63417792 |
| 39 | MP0008469_abnormal_protein_level | 1.63029150 |
| 40 | MP0008260_abnormal_autophagy | 1.60521943 |
| 41 | MP0005058_abnormal_lysosome_morphology | 1.60230389 |
| 42 | MP0009840_abnormal_foam_cell | 1.58826626 |
| 43 | MP0009764_decreased_sensitivity_to | 1.57445630 |
| 44 | MP0000716_abnormal_immune_system | 1.51363923 |
| 45 | MP0002398_abnormal_bone_marrow | 1.46609038 |
| 46 | MP0010329_abnormal_lipoprotein_level | 1.44542450 |
| 47 | MP0009333_abnormal_splenocyte_physiolog | 1.41939110 |
| 48 | MP0004883_abnormal_blood_vessel | 1.41428573 |
| 49 | MP0005377_hearing/vestibular/ear_phenot | 1.37862691 |
| 50 | MP0003878_abnormal_ear_physiology | 1.37862691 |
| 51 | MP0003075_altered_response_to | 1.36986447 |
| 52 | MP0005397_hematopoietic_system_phenotyp | 1.36068951 |
| 53 | MP0001545_abnormal_hematopoietic_system | 1.36068951 |
| 54 | MP0003763_abnormal_thymus_physiology | 1.35630675 |
| 55 | MP0003866_abnormal_defecation | 1.34635451 |
| 56 | MP0008875_abnormal_xenobiotic_pharmacok | 1.33569150 |
| 57 | MP0003806_abnormal_nucleotide_metabolis | 1.33463511 |
| 58 | MP0002277_abnormal_respiratory_mucosa | 1.32954663 |
| 59 | MP0002396_abnormal_hematopoietic_system | 1.32703271 |
| 60 | MP0004947_skin_inflammation | 1.28466137 |
| 61 | MP0003828_pulmonary_edema | 1.28101688 |
| 62 | MP0004381_abnormal_hair_follicle | 1.25729801 |
| 63 | MP0000689_abnormal_spleen_morphology | 1.24569436 |
| 64 | MP0002722_abnormal_immune_system | 1.22226885 |
| 65 | MP0001851_eye_inflammation | 1.22160881 |
| 66 | MP0000465_gastrointestinal_hemorrhage | 1.18811243 |
| 67 | MP0002429_abnormal_blood_cell | 1.18188944 |
| 68 | MP0000858_altered_metastatic_potential | 1.16671482 |
| 69 | MP0005164_abnormal_response_to | 1.14385536 |
| 70 | MP0002998_abnormal_bone_remodeling | 1.14257118 |
| 71 | MP0000609_abnormal_liver_physiology | 1.12125850 |
| 72 | MP0003690_abnormal_glial_cell | 1.04987610 |
| 73 | MP0001666_abnormal_nutrient_absorption | 1.00946641 |
| 74 | MP0005319_abnormal_enzyme/_coenzyme | 1.00375725 |
| 75 | MP0005166_decreased_susceptibility_to | 0.98889275 |
| 76 | MP0009763_increased_sensitivity_to | 0.96874252 |
| 77 | MP0000604_amyloidosis | 0.96459933 |
| 78 | MP0002118_abnormal_lipid_homeostasis | 0.96007654 |
| 79 | MP0004510_myositis | 0.91876108 |
| 80 | MP0001986_abnormal_taste_sensitivity | 0.91173561 |
| 81 | MP0005310_abnormal_salivary_gland | 0.90555443 |
| 82 | MP0000703_abnormal_thymus_morphology | 0.84892846 |
| 83 | MP0003656_abnormal_erythrocyte_physiolo | 0.80186122 |
| 84 | MP0001663_abnormal_digestive_system | 0.79884086 |
| 85 | MP0008874_decreased_physiological_sensi | 0.76405569 |
| 86 | MP0002933_joint_inflammation | 0.76091354 |
| 87 | MP0004130_abnormal_muscle_cell | 0.75491907 |
| 88 | MP0005390_skeleton_phenotype | 0.73335974 |
| 89 | MP0000249_abnormal_blood_vessel | 0.73012022 |
| 90 | MP0005083_abnormal_biliary_tract | 0.68673133 |
| 91 | MP0001853_heart_inflammation | 0.68331310 |
| 92 | MP0009642_abnormal_blood_homeostasis | 0.67141779 |
| 93 | MP0003879_abnormal_hair_cell | 0.67135522 |
| 94 | MP0005376_homeostasis/metabolism_phenot | 0.66762642 |
| 95 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.66151200 |
| 96 | MP0000343_altered_response_to | 0.66122957 |
| 97 | MP0002971_abnormal_brown_adipose | 0.65708850 |
| 98 | MP0005076_abnormal_cell_differentiation | 0.64173533 |
| 99 | MP0000598_abnormal_liver_morphology | 0.64041569 |
| 100 | MP0005332_abnormal_amino_acid | 0.63408354 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Recurrent gram-negative bacterial infections (HP:0005420) | 5.97519500 |
| 2 | Eczematoid dermatitis (HP:0000976) | 5.84595334 |
| 3 | Myositis (HP:0100614) | 5.28118857 |
| 4 | Recurrent abscess formation (HP:0002722) | 5.10738603 |
| 5 | Orchitis (HP:0100796) | 4.89900002 |
| 6 | Recurrent bacterial skin infections (HP:0005406) | 4.75093621 |
| 7 | Abnormality of macrophages (HP:0004311) | 4.74783508 |
| 8 | Deep venous thrombosis (HP:0002625) | 4.68309405 |
| 9 | Retrobulbar optic neuritis (HP:0100654) | 4.53548381 |
| 10 | Optic neuritis (HP:0100653) | 4.53548381 |
| 11 | Hypochromic microcytic anemia (HP:0004840) | 4.08550381 |
| 12 | Joint hemorrhage (HP:0005261) | 3.99950151 |
| 13 | Systemic lupus erythematosus (HP:0002725) | 3.98482388 |
| 14 | Chronic obstructive pulmonary disease (HP:0006510) | 3.92843675 |
| 15 | Obstructive lung disease (HP:0006536) | 3.92843675 |
| 16 | Gastrointestinal infarctions (HP:0005244) | 3.81772880 |
| 17 | Stomatitis (HP:0010280) | 3.74613778 |
| 18 | Meningitis (HP:0001287) | 3.71736320 |
| 19 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.71479074 |
| 20 | Hypochromic anemia (HP:0001931) | 3.68297996 |
| 21 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 3.65212105 |
| 22 | Mediastinal lymphadenopathy (HP:0100721) | 3.61007725 |
| 23 | Gingival bleeding (HP:0000225) | 3.55464129 |
| 24 | Keratoconjunctivitis sicca (HP:0001097) | 3.38621376 |
| 25 | Complement deficiency (HP:0004431) | 3.35987836 |
| 26 | Prolonged bleeding time (HP:0003010) | 3.35439805 |
| 27 | Prolonged partial thromboplastin time (HP:0003645) | 3.32642515 |
| 28 | Gingivitis (HP:0000230) | 3.28435039 |
| 29 | Recurrent fungal infections (HP:0002841) | 3.25115823 |
| 30 | Pulmonary embolism (HP:0002204) | 3.20837002 |
| 31 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.18666918 |
| 32 | Purpura (HP:0000979) | 3.18380421 |
| 33 | Recurrent skin infections (HP:0001581) | 3.15571518 |
| 34 | Encephalitis (HP:0002383) | 3.14707784 |
| 35 | Abnormality of complement system (HP:0005339) | 3.13712503 |
| 36 | Epistaxis (HP:0000421) | 3.13330614 |
| 37 | Increased IgE level (HP:0003212) | 3.12548632 |
| 38 | Vasculitis (HP:0002633) | 3.11251452 |
| 39 | Spontaneous hematomas (HP:0007420) | 3.11099283 |
| 40 | Keratoconjunctivitis (HP:0001096) | 3.07656266 |
| 41 | Urticaria (HP:0001025) | 3.05268641 |
| 42 | Glomerulonephritis (HP:0000099) | 2.87780592 |
| 43 | Hypobetalipoproteinemia (HP:0003563) | 2.85206525 |
| 44 | Hemorrhage of the eye (HP:0011885) | 2.80827304 |
| 45 | Pulmonary infiltrates (HP:0002113) | 2.79727584 |
| 46 | Amyloidosis (HP:0011034) | 2.75690964 |
| 47 | Peritonitis (HP:0002586) | 2.74822779 |
| 48 | Gangrene (HP:0100758) | 2.74555331 |
| 49 | Chest pain (HP:0100749) | 2.72803313 |
| 50 | Hemoptysis (HP:0002105) | 2.71985101 |
| 51 | Anorexia (HP:0002039) | 2.70352394 |
| 52 | Cellulitis (HP:0100658) | 2.67965817 |
| 53 | Hyperlipoproteinemia (HP:0010980) | 2.67740571 |
| 54 | Episodic fever (HP:0001954) | 2.62644424 |
| 55 | Abnormality of the common coagulation pathway (HP:0010990) | 2.57651083 |
| 56 | Xanthomatosis (HP:0000991) | 2.56799193 |
| 57 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.55591942 |
| 58 | Recurrent cutaneous fungal infections (HP:0011370) | 2.55591942 |
| 59 | Arterial thrombosis (HP:0004420) | 2.52692796 |
| 60 | Granulocytopenia (HP:0001913) | 2.50969782 |
| 61 | Menorrhagia (HP:0000132) | 2.50686054 |
| 62 | Petechiae (HP:0000967) | 2.49925642 |
| 63 | Thrombophlebitis (HP:0004418) | 2.46112930 |
| 64 | Increased serum ferritin (HP:0003281) | 2.38265925 |
| 65 | Leukocytosis (HP:0001974) | 2.38003847 |
| 66 | Inflammation of the large intestine (HP:0002037) | 2.34920488 |
| 67 | Microcytic anemia (HP:0001935) | 2.33560449 |
| 68 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 2.32658438 |
| 69 | Gastrointestinal inflammation (HP:0004386) | 2.31340079 |
| 70 | Abnormality of iron homeostasis (HP:0011031) | 2.30917586 |
| 71 | Abnormality of the pleura (HP:0002103) | 2.29976863 |
| 72 | Abnormal platelet volume (HP:0011876) | 2.27647167 |
| 73 | Pustule (HP:0200039) | 2.26236208 |
| 74 | Hypergammaglobulinemia (HP:0010702) | 2.23945915 |
| 75 | Increased IgM level (HP:0003496) | 2.20134890 |
| 76 | Abnormality of pyrimidine metabolism (HP:0004353) | 2.11776847 |
| 77 | Osteomyelitis (HP:0002754) | 2.10858547 |
| 78 | Loss of speech (HP:0002371) | 2.10563341 |
| 79 | Abnormality of the peritoneum (HP:0002585) | 2.08545186 |
| 80 | Eosinophilia (HP:0001880) | 2.07127392 |
| 81 | Sepsis (HP:0100806) | 2.06827228 |
| 82 | Increased cerebral lipofuscin (HP:0011813) | 2.06442886 |
| 83 | Hypertriglyceridemia (HP:0002155) | 2.03601810 |
| 84 | Polycythemia (HP:0001901) | 2.02495200 |
| 85 | Glomerulopathy (HP:0100820) | 2.02302614 |
| 86 | Joint swelling (HP:0001386) | 2.01551393 |
| 87 | Nephritis (HP:0000123) | 2.01416681 |
| 88 | Acne (HP:0001061) | 2.01411193 |
| 89 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.00590462 |
| 90 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.00590462 |
| 91 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.00590462 |
| 92 | Periodontitis (HP:0000704) | 2.00568699 |
| 93 | Dysostosis multiplex (HP:0000943) | 2.00401174 |
| 94 | Metaphyseal cupping (HP:0003021) | 1.96884912 |
| 95 | Myocardial infarction (HP:0001658) | 1.95098304 |
| 96 | Mucopolysacchariduria (HP:0008155) | 1.94700350 |
| 97 | Urinary glycosaminoglycan excretion (HP:0003541) | 1.94700350 |
| 98 | Thrombocytosis (HP:0001894) | 1.94001388 |
| 99 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.92514884 |
| 100 | Recurrent viral infections (HP:0004429) | 1.91064581 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RIPK4 | 4.62906943 |
| 2 | ERN1 | 4.29252930 |
| 3 | MAP4K1 | 3.49231632 |
| 4 | IRAK4 | 3.29839880 |
| 5 | MAP2K3 | 2.99133913 |
| 6 | TYK2 | 2.88139126 |
| 7 | BLK | 2.73221387 |
| 8 | TNK2 | 2.55435633 |
| 9 | CSK | 2.45278108 |
| 10 | FES | 2.20305267 |
| 11 | GRK6 | 2.17677157 |
| 12 | ZAP70 | 1.98365436 |
| 13 | PRPF4B | 1.95970262 |
| 14 | EPHB1 | 1.94613856 |
| 15 | TAOK1 | 1.93911365 |
| 16 | MAP3K3 | 1.87493351 |
| 17 | MAP3K11 | 1.83093716 |
| 18 | BTK | 1.66583792 |
| 19 | HCK | 1.65106931 |
| 20 | SYK | 1.56973347 |
| 21 | FGR | 1.56666676 |
| 22 | TBK1 | 1.46418924 |
| 23 | JAK3 | 1.46295744 |
| 24 | TRIB3 | 1.46182604 |
| 25 | CSF1R | 1.43259168 |
| 26 | FGFR4 | 1.42440107 |
| 27 | KIT | 1.37991645 |
| 28 | MAP3K1 | 1.37048092 |
| 29 | MAP3K14 | 1.32173384 |
| 30 | JAK2 | 1.30269877 |
| 31 | KSR2 | 1.28737629 |
| 32 | LYN | 1.28598775 |
| 33 | IKBKE | 1.24983485 |
| 34 | TXK | 1.21966832 |
| 35 | TAOK3 | 1.17247275 |
| 36 | PTK6 | 1.14038303 |
| 37 | SIK3 | 1.12582150 |
| 38 | LCK | 1.12201773 |
| 39 | MATK | 1.11549983 |
| 40 | SIK2 | 1.09444820 |
| 41 | YES1 | 1.06084029 |
| 42 | IRAK2 | 1.03801044 |
| 43 | JAK1 | 1.03114899 |
| 44 | SIK1 | 1.02566555 |
| 45 | IRAK1 | 1.01620689 |
| 46 | MARK2 | 0.98672958 |
| 47 | PRKD2 | 0.98127715 |
| 48 | MAP3K13 | 0.97105951 |
| 49 | PDPK1 | 0.96654223 |
| 50 | PDK1 | 0.95737983 |
| 51 | SMG1 | 0.95734026 |
| 52 | TAOK2 | 0.95593119 |
| 53 | ITK | 0.87775213 |
| 54 | MAP3K6 | 0.86197073 |
| 55 | TESK2 | 0.85886708 |
| 56 | PIK3CG | 0.84845087 |
| 57 | FGFR3 | 0.82490120 |
| 58 | MAP3K2 | 0.82335166 |
| 59 | MARK3 | 0.81949476 |
| 60 | MAP2K4 | 0.76049666 |
| 61 | CDC42BPA | 0.72776715 |
| 62 | DYRK1B | 0.72543272 |
| 63 | MAP3K7 | 0.70108835 |
| 64 | TEC | 0.70047085 |
| 65 | IKBKB | 0.68762193 |
| 66 | PRKG2 | 0.68750490 |
| 67 | FYN | 0.67942102 |
| 68 | STK38 | 0.65780031 |
| 69 | TGFBR2 | 0.65506095 |
| 70 | CDK19 | 0.65228489 |
| 71 | MAPK12 | 0.64262714 |
| 72 | CDK12 | 0.63868516 |
| 73 | DAPK2 | 0.63668992 |
| 74 | MAP2K6 | 0.63306687 |
| 75 | IRAK3 | 0.61011008 |
| 76 | RET | 0.58525324 |
| 77 | PTK2B | 0.57123010 |
| 78 | ICK | 0.56000624 |
| 79 | RIPK1 | 0.54154606 |
| 80 | STK10 | 0.50772767 |
| 81 | HIPK2 | 0.50153800 |
| 82 | PRKCQ | 0.49885158 |
| 83 | LRRK2 | 0.49858929 |
| 84 | RPS6KC1 | 0.48596762 |
| 85 | RPS6KL1 | 0.48596762 |
| 86 | MAP3K5 | 0.48563517 |
| 87 | MAPK7 | 0.48362194 |
| 88 | PRKAA2 | 0.46051223 |
| 89 | BMPR2 | 0.45132839 |
| 90 | PRKCZ | 0.44923744 |
| 91 | STK11 | 0.44241748 |
| 92 | SGK3 | 0.43956252 |
| 93 | RPS6KA6 | 0.40973296 |
| 94 | MAPK11 | 0.39617701 |
| 95 | EPHA3 | 0.39492785 |
| 96 | MAPKAPK2 | 0.36110157 |
| 97 | BMX | 0.30069561 |
| 98 | MAPK4 | 0.29559042 |
| 99 | RPS6KA1 | 0.29474257 |
| 100 | PRKCD | 0.29005932 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 3.89583360 |
| 2 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 3.04588666 |
| 3 | Leishmaniasis_Homo sapiens_hsa05140 | 2.66255379 |
| 4 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.62154227 |
| 5 | Other glycan degradation_Homo sapiens_hsa00511 | 1.90403994 |
| 6 | Allograft rejection_Homo sapiens_hsa05330 | 1.89281670 |
| 7 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.87681412 |
| 8 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.86072259 |
| 9 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.81325157 |
| 10 | Tuberculosis_Homo sapiens_hsa05152 | 1.79706625 |
| 11 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.77317005 |
| 12 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.72589016 |
| 13 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.71465629 |
| 14 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.68722769 |
| 15 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.61063319 |
| 16 | Malaria_Homo sapiens_hsa05144 | 1.61004132 |
| 17 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.59610374 |
| 18 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.58600996 |
| 19 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.52963437 |
| 20 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.50579967 |
| 21 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.40654622 |
| 22 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.39281669 |
| 23 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.37297493 |
| 24 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.37284910 |
| 25 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.32896972 |
| 26 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.30504526 |
| 27 | Retinol metabolism_Homo sapiens_hsa00830 | 1.28727128 |
| 28 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.28511106 |
| 29 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.27966204 |
| 30 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.26985326 |
| 31 | Pertussis_Homo sapiens_hsa05133 | 1.26466595 |
| 32 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.24719056 |
| 33 | Measles_Homo sapiens_hsa05162 | 1.24477622 |
| 34 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.22137169 |
| 35 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.20929961 |
| 36 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.16880009 |
| 37 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.15930254 |
| 38 | Influenza A_Homo sapiens_hsa05164 | 1.12523544 |
| 39 | Phagosome_Homo sapiens_hsa04145 | 1.12417116 |
| 40 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.12284567 |
| 41 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.06568047 |
| 42 | Legionellosis_Homo sapiens_hsa05134 | 1.02168041 |
| 43 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.01766270 |
| 44 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.00694513 |
| 45 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.99686935 |
| 46 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.98999588 |
| 47 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.98807395 |
| 48 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.98368416 |
| 49 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.97724316 |
| 50 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.96191000 |
| 51 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.95386756 |
| 52 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.95319822 |
| 53 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.95288173 |
| 54 | Viral myocarditis_Homo sapiens_hsa05416 | 0.95270774 |
| 55 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.94262589 |
| 56 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.92685126 |
| 57 | Platelet activation_Homo sapiens_hsa04611 | 0.92669466 |
| 58 | Asthma_Homo sapiens_hsa05310 | 0.92609969 |
| 59 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.92400173 |
| 60 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.91084883 |
| 61 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.90618839 |
| 62 | Hepatitis C_Homo sapiens_hsa05160 | 0.90038469 |
| 63 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.89796014 |
| 64 | Histidine metabolism_Homo sapiens_hsa00340 | 0.83575529 |
| 65 | Lysosome_Homo sapiens_hsa04142 | 0.82586992 |
| 66 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.82050057 |
| 67 | Bile secretion_Homo sapiens_hsa04976 | 0.81184479 |
| 68 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.80589397 |
| 69 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.79244516 |
| 70 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.78837600 |
| 71 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.77183456 |
| 72 | Insulin resistance_Homo sapiens_hsa04931 | 0.73967327 |
| 73 | Amoebiasis_Homo sapiens_hsa05146 | 0.69298319 |
| 74 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.66296542 |
| 75 | Hepatitis B_Homo sapiens_hsa05161 | 0.65823859 |
| 76 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.65639365 |
| 77 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.64863269 |
| 78 | Salmonella infection_Homo sapiens_hsa05132 | 0.59616637 |
| 79 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.58619891 |
| 80 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.58358939 |
| 81 | ABC transporters_Homo sapiens_hsa02010 | 0.57557675 |
| 82 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.54799783 |
| 83 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.53496038 |
| 84 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.52743090 |
| 85 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.52223643 |
| 86 | Apoptosis_Homo sapiens_hsa04210 | 0.52019069 |
| 87 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.51999175 |
| 88 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.51496177 |
| 89 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.51319332 |
| 90 | Prion diseases_Homo sapiens_hsa05020 | 0.51319016 |
| 91 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.49883420 |
| 92 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.48317090 |
| 93 | Shigellosis_Homo sapiens_hsa05131 | 0.47437571 |
| 94 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.47042633 |
| 95 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.46624555 |
| 96 | Galactose metabolism_Homo sapiens_hsa00052 | 0.45754333 |
| 97 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.45480737 |
| 98 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.43349820 |
| 99 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.41662475 |
| 100 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.38979221 |

