Rank | Gene Set | Z-score |
---|---|---|
1 | modulation by symbiont of host defense response (GO:0052031) | 6.22007069 |
2 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 6.22007069 |
3 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 6.22007069 |
4 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 6.22007069 |
5 | modulation by symbiont of host immune response (GO:0052553) | 6.22007069 |
6 | positive regulation by symbiont of host defense response (GO:0052509) | 6.22007069 |
7 | regulation of interferon-beta biosynthetic process (GO:0045357) | 5.42007172 |
8 | microglial cell activation (GO:0001774) | 5.23773685 |
9 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.12190145 |
10 | macrophage activation involved in immune response (GO:0002281) | 4.88556676 |
11 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.37125947 |
12 | negative regulation of granulocyte differentiation (GO:0030853) | 4.29131238 |
13 | tolerance induction (GO:0002507) | 4.23968893 |
14 | regulation of chronic inflammatory response (GO:0002676) | 4.19046528 |
15 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.19028391 |
16 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.07683488 |
17 | negative regulation of cell killing (GO:0031342) | 4.07683488 |
18 | regulation of vitamin D biosynthetic process (GO:0060556) | 4.03157388 |
19 | regulation of T-helper 1 cell differentiation (GO:0045625) | 4.01491515 |
20 | positive regulation of chemokine secretion (GO:0090197) | 3.99745192 |
21 | positive regulation of interferon-alpha production (GO:0032727) | 3.99553159 |
22 | regulation of interferon-alpha production (GO:0032647) | 3.95641922 |
23 | macrophage activation (GO:0042116) | 3.89605732 |
24 | response to host immune response (GO:0052572) | 3.88917315 |
25 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.88917315 |
26 | positive regulation of cellular amide metabolic process (GO:0034250) | 3.70089788 |
27 | type I interferon signaling pathway (GO:0060337) | 3.68153997 |
28 | cellular response to type I interferon (GO:0071357) | 3.68153997 |
29 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.64502118 |
30 | response to host (GO:0075136) | 3.64502118 |
31 | response to host defenses (GO:0052200) | 3.64502118 |
32 | response to type I interferon (GO:0034340) | 3.64236705 |
33 | positive regulation of heat generation (GO:0031652) | 3.62956386 |
34 | positive regulation of B cell differentiation (GO:0045579) | 3.57684571 |
35 | neutrophil activation involved in immune response (GO:0002283) | 3.55386680 |
36 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.54589488 |
37 | cellular extravasation (GO:0045123) | 3.53314913 |
38 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 3.49831402 |
39 | myeloid cell activation involved in immune response (GO:0002275) | 3.49129826 |
40 | positive regulation of type 2 immune response (GO:0002830) | 3.48721833 |
41 | mannose metabolic process (GO:0006013) | 3.47844686 |
42 | negative regulation of interleukin-12 production (GO:0032695) | 3.45336785 |
43 | regulation of T cell tolerance induction (GO:0002664) | 3.40891301 |
44 | regulation of fever generation (GO:0031620) | 3.40534491 |
45 | I-kappaB phosphorylation (GO:0007252) | 3.40362484 |
46 | leukocyte aggregation (GO:0070486) | 3.38085508 |
47 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 3.37326301 |
48 | detection of molecule of bacterial origin (GO:0032490) | 3.35829164 |
49 | positive thymic T cell selection (GO:0045059) | 3.33359740 |
50 | positive regulation of antigen processing and presentation (GO:0002579) | 3.31406008 |
51 | regulation of chemokine secretion (GO:0090196) | 3.28434248 |
52 | T cell migration (GO:0072678) | 3.25676178 |
53 | pinocytosis (GO:0006907) | 3.22542596 |
54 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.22410486 |
55 | defense response to protozoan (GO:0042832) | 3.22097148 |
56 | regulation of interleukin-12 production (GO:0032655) | 3.21403137 |
57 | immunoglobulin mediated immune response (GO:0016064) | 3.20764628 |
58 | regulation of cytokine secretion involved in immune response (GO:0002739) | 3.20746659 |
59 | T-helper 1 type immune response (GO:0042088) | 3.18225856 |
60 | response to muramyl dipeptide (GO:0032495) | 3.17724457 |
61 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.16865581 |
62 | negative regulation of interleukin-6 production (GO:0032715) | 3.09533666 |
63 | regulation of mast cell degranulation (GO:0043304) | 3.09407116 |
64 | mast cell activation (GO:0045576) | 3.08501284 |
65 | negative regulation of B cell proliferation (GO:0030889) | 3.08251183 |
66 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 3.07398268 |
67 | response to protozoan (GO:0001562) | 3.07116682 |
68 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 3.06152872 |
69 | regulation of heat generation (GO:0031650) | 3.04920274 |
70 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 3.03471965 |
71 | negative regulation of cytokine production involved in immune response (GO:0002719) | 3.02972069 |
72 | positive regulation of chemokine biosynthetic process (GO:0045080) | 3.02571687 |
73 | regulation of vitamin metabolic process (GO:0030656) | 2.98604654 |
74 | positive regulation of NF-kappaB import into nucleus (GO:0042346) | 2.97704244 |
75 | tryptophan catabolic process (GO:0006569) | 2.96167479 |
76 | indole-containing compound catabolic process (GO:0042436) | 2.96167479 |
77 | indolalkylamine catabolic process (GO:0046218) | 2.96167479 |
78 | regulation of mast cell activation involved in immune response (GO:0033006) | 2.95125900 |
79 | positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372) | 2.93264996 |
80 | regulation of type 2 immune response (GO:0002828) | 2.93132875 |
81 | regulation of gamma-delta T cell activation (GO:0046643) | 2.92151779 |
82 | response to peptidoglycan (GO:0032494) | 2.92087234 |
83 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 2.91836458 |
84 | regulation of T-helper 1 type immune response (GO:0002825) | 2.90640925 |
85 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 2.89724706 |
86 | positive regulation of mast cell activation (GO:0033005) | 2.88882355 |
87 | regulation of mononuclear cell migration (GO:0071675) | 2.88161828 |
88 | positive regulation of interleukin-12 production (GO:0032735) | 2.87816323 |
89 | phagocytosis, engulfment (GO:0006911) | 2.86756885 |
90 | cellular response to ethanol (GO:0071361) | 2.86069950 |
91 | B cell homeostasis (GO:0001782) | 2.85970301 |
92 | lymphocyte chemotaxis (GO:0048247) | 2.85833665 |
93 | positive regulation of interferon-gamma biosynthetic process (GO:0045078) | 2.85508776 |
94 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 2.85447643 |
95 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.84661178 |
96 | NIK/NF-kappaB signaling (GO:0038061) | 2.84131309 |
97 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.82911140 |
98 | regulation of T-helper cell differentiation (GO:0045622) | 2.82848960 |
99 | neutrophil activation (GO:0042119) | 2.82604128 |
100 | hyaluronan catabolic process (GO:0030214) | 2.82401611 |
101 | myeloid leukocyte activation (GO:0002274) | 2.82157148 |
102 | regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370) | 2.82071365 |
103 | negative regulation of T cell mediated immunity (GO:0002710) | 2.81500297 |
104 | antigen processing and presentation of endogenous antigen (GO:0019883) | 2.80601404 |
105 | cellular response to interferon-gamma (GO:0071346) | 2.80057917 |
106 | positive regulation of T-helper 1 type immune response (GO:0002827) | 2.80014483 |
107 | regulation of mast cell activation (GO:0033003) | 2.79221419 |
108 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 2.78058271 |
109 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 2.77659953 |
110 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 2.77659953 |
111 | regulation of chemokine biosynthetic process (GO:0045073) | 2.76520733 |
112 | regulation of interleukin-8 biosynthetic process (GO:0045414) | 2.76353163 |
113 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 2.75875852 |
114 | positive regulation of mast cell degranulation (GO:0043306) | 2.75875852 |
115 | regulation of B cell differentiation (GO:0045577) | 2.75660516 |
116 | positive regulation of T-helper cell differentiation (GO:0045624) | 2.73991998 |
117 | kynurenine metabolic process (GO:0070189) | 2.73775890 |
118 | regulation of inflammatory response to antigenic stimulus (GO:0002861) | 2.73687714 |
119 | granulocyte activation (GO:0036230) | 2.72908400 |
120 | positive regulation of defense response to virus by host (GO:0002230) | 2.72894025 |
121 | modulation of growth of symbiont involved in interaction with host (GO:0044144) | 2.72679075 |
122 | regulation of growth of symbiont in host (GO:0044126) | 2.72679075 |
123 | negative regulation of growth of symbiont in host (GO:0044130) | 2.72679075 |
124 | negative regulation of growth of symbiont involved in interaction with host (GO:0044146) | 2.72679075 |
125 | positive regulation of interferon-beta production (GO:0032728) | 2.71407142 |
126 | B cell receptor signaling pathway (GO:0050853) | 2.68701519 |
127 | germinal center formation (GO:0002467) | 2.68694649 |
128 | regulation of lymphocyte chemotaxis (GO:1901623) | 2.68472160 |
129 | response to interferon-gamma (GO:0034341) | 2.67968479 |
130 | regulation of antigen processing and presentation (GO:0002577) | 2.67159816 |
131 | positive regulation of macrophage differentiation (GO:0045651) | 2.65583666 |
132 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 2.63125807 |
133 | positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557) | 2.62996401 |
134 | negative regulation of toll-like receptor 4 signaling pathway (GO:0034144) | 2.62710897 |
135 | regulation of podosome assembly (GO:0071801) | 2.62513932 |
136 | polyketide metabolic process (GO:0030638) | 2.62251056 |
137 | doxorubicin metabolic process (GO:0044598) | 2.62251056 |
138 | daunorubicin metabolic process (GO:0044597) | 2.62251056 |
139 | regulation of leukocyte degranulation (GO:0043300) | 2.62204286 |
140 | leukocyte cell-cell adhesion (GO:0007159) | 2.61620158 |
141 | myeloid dendritic cell differentiation (GO:0043011) | 2.61462818 |
142 | response to laminar fluid shear stress (GO:0034616) | 2.60778484 |
143 | cellular response to molecule of bacterial origin (GO:0071219) | 2.60777747 |
144 | cellular response to lipopolysaccharide (GO:0071222) | 2.59561815 |
145 | respiratory burst (GO:0045730) | 2.58478933 |
146 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.57311175 |
147 | regulation of tolerance induction (GO:0002643) | 2.56333960 |
148 | regulation of granulocyte differentiation (GO:0030852) | 2.54373052 |
149 | negative thymic T cell selection (GO:0045060) | 2.54150243 |
150 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 2.53548275 |
151 | cytokine secretion (GO:0050663) | 2.52049483 |
152 | interferon-gamma production (GO:0032609) | 2.51245233 |
153 | positive T cell selection (GO:0043368) | 2.50114741 |
154 | positive regulation of tumor necrosis factor production (GO:0032760) | 2.48867476 |
155 | production of molecular mediator involved in inflammatory response (GO:0002532) | 2.48568061 |
156 | positive regulation of leukocyte degranulation (GO:0043302) | 2.47713651 |
157 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 2.47177373 |
158 | glycosphingolipid catabolic process (GO:0046479) | 2.47000439 |
159 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 2.46760988 |
160 | negative T cell selection (GO:0043383) | 2.44965863 |
161 | modulation by symbiont of host cellular process (GO:0044068) | 2.44718659 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 6.68193552 |
2 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 4.88120050 |
3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 4.68284607 |
4 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 4.16527383 |
5 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.11868316 |
6 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 4.04409573 |
7 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.95094000 |
8 | * MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.27974275 |
9 | * NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.12546007 |
10 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.03493721 |
11 | * SCL_19346495_ChIP-Seq_HPC-7_Human | 2.82232793 |
12 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.80903493 |
13 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.74020831 |
14 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 2.56794915 |
15 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.53411182 |
16 | GATA1_22025678_ChIP-Seq_K562_Human | 2.49379812 |
17 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.41624925 |
18 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.36954311 |
19 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.32055987 |
20 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.25982007 |
21 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.20621667 |
22 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.14402944 |
23 | SPI1_23127762_ChIP-Seq_K562_Human | 2.07219972 |
24 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.97729295 |
25 | * STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.96038524 |
26 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.89922934 |
27 | * RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.79000333 |
28 | * MYB_26560356_Chip-Seq_TH2_Human | 1.78957264 |
29 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.75699355 |
30 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.75185149 |
31 | * VDR_24787735_ChIP-Seq_THP-1_Human | 1.72863553 |
32 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.72674328 |
33 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.71067508 |
34 | MAF_26560356_Chip-Seq_TH1_Human | 1.68864230 |
35 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.68623861 |
36 | * RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.65972655 |
37 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.65201325 |
38 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.63117865 |
39 | * VDR_24763502_ChIP-Seq_THP-1_Human | 1.57821724 |
40 | GATA1_19941826_ChIP-Seq_K562_Human | 1.52741814 |
41 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.52517504 |
42 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.51301903 |
43 | * LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.50891065 |
44 | * VDR_21846776_ChIP-Seq_THP-1_Human | 1.50059421 |
45 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.48785967 |
46 | * GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.48437534 |
47 | * MYB_26560356_Chip-Seq_TH1_Human | 1.48167155 |
48 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.41263969 |
49 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.41247964 |
50 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.38290758 |
51 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.37160582 |
52 | * LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.36146458 |
53 | GATA2_19941826_ChIP-Seq_K562_Human | 1.33716473 |
54 | * STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.32452544 |
55 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.31703186 |
56 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.24413549 |
57 | MYC_22102868_ChIP-Seq_BL_Human | 1.20860674 |
58 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.20267246 |
59 | * UTX_26944678_Chip-Seq_JUKART_Human | 1.19266909 |
60 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.14935669 |
61 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.14463252 |
62 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.14023225 |
63 | * GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.13472017 |
64 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.11577322 |
65 | * BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.10221505 |
66 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.08347783 |
67 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.03618067 |
68 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.03055905 |
69 | * TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.02084808 |
70 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.00570242 |
71 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.99329975 |
72 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.99293366 |
73 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.97388665 |
74 | GATA3_26560356_Chip-Seq_TH2_Human | 0.96306336 |
75 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.95419047 |
76 | DROSHA_22980978_ChIP-Seq_HELA_Human | 0.93276132 |
77 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.93207630 |
78 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.92588065 |
79 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.92525055 |
80 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.92342423 |
81 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.91673765 |
82 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.89642193 |
83 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.89403101 |
84 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.88615146 |
85 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 0.88332140 |
86 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.86722843 |
87 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.86509407 |
88 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.84976856 |
89 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.84710282 |
90 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 0.84508398 |
91 | TP53_16413492_ChIP-PET_HCT116_Human | 0.82811026 |
92 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.82608251 |
93 | MAF_26560356_Chip-Seq_TH2_Human | 0.82212012 |
94 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.80618518 |
95 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 0.80599749 |
96 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.80174845 |
97 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.80054332 |
98 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.79989221 |
99 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.79107816 |
100 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.78792531 |
101 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 0.78671064 |
102 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 0.77630039 |
103 | CJUN_26792858_Chip-Seq_BT549_Human | 0.77139967 |
104 | REST_21632747_ChIP-Seq_MESCs_Mouse | 0.74817123 |
105 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.74516682 |
106 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.72412516 |
107 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.71153013 |
108 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.71153013 |
109 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.70695932 |
110 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 0.70577625 |
111 | PU1_27457419_Chip-Seq_LIVER_Mouse | 0.70083144 |
112 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.69773066 |
113 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 0.68867623 |
114 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 0.68335765 |
115 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.68247986 |
116 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.67995226 |
117 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.67329460 |
118 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.67224051 |
119 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.66738087 |
120 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.66536126 |
121 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 0.66527771 |
122 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 0.66024964 |
123 | * TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.65414024 |
124 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.64710884 |
125 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 0.64256907 |
126 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.61936004 |
127 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 0.60980773 |
128 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.60827837 |
129 | * SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.60739056 |
130 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 0.60063378 |
131 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.59836640 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0005058_abnormal_lysosome_morphology | 4.05007231 |
2 | MP0001835_abnormal_antigen_presentation | 3.42576544 |
3 | MP0006082_CNS_inflammation | 3.28392332 |
4 | MP0005671_abnormal_response_to | 3.18553072 |
5 | MP0003436_decreased_susceptibility_to | 2.88917125 |
6 | * MP0002419_abnormal_innate_immunity | 2.87518353 |
7 | MP0003303_peritoneal_inflammation | 2.81240989 |
8 | MP0003172_abnormal_lysosome_physiology | 2.80489566 |
9 | MP0003191_abnormal_cellular_cholesterol | 2.77390130 |
10 | MP0005464_abnormal_platelet_physiology | 2.70097104 |
11 | MP0005000_abnormal_immune_tolerance | 2.67737274 |
12 | MP0001790_abnormal_immune_system | 2.66815213 |
13 | MP0005387_immune_system_phenotype | 2.66815213 |
14 | MP0003300_gastrointestinal_ulcer | 2.59171856 |
15 | MP0001800_abnormal_humoral_immune | 2.56640185 |
16 | MP0002148_abnormal_hypersensitivity_rea | 2.51395784 |
17 | * MP0002452_abnormal_antigen_presenting | 2.48128824 |
18 | * MP0002723_abnormal_immune_serum | 2.41088932 |
19 | MP0005025_abnormal_response_to | 2.37016021 |
20 | * MP0001819_abnormal_immune_cell | 2.22282544 |
21 | * MP0002420_abnormal_adaptive_immunity | 2.21761060 |
22 | MP0000685_abnormal_immune_system | 2.18481448 |
23 | MP0000569_abnormal_digit_pigmentation | 2.17982334 |
24 | MP0003724_increased_susceptibility_to | 2.06212787 |
25 | MP0003690_abnormal_glial_cell | 2.05829881 |
26 | MP0009785_altered_susceptibility_to | 2.00709782 |
27 | MP0004510_myositis | 1.99024524 |
28 | MP0000465_gastrointestinal_hemorrhage | 1.96167883 |
29 | MP0002405_respiratory_system_inflammati | 1.92897307 |
30 | MP0003045_fibrosis | 1.82595691 |
31 | * MP0001533_abnormal_skeleton_physiology | 1.80880044 |
32 | MP0003763_abnormal_thymus_physiology | 1.80246478 |
33 | MP0009840_abnormal_foam_cell | 1.77091671 |
34 | MP0003195_calcinosis | 1.70451387 |
35 | MP0005310_abnormal_salivary_gland | 1.68945261 |
36 | MP0001853_heart_inflammation | 1.67548625 |
37 | MP0002398_abnormal_bone_marrow | 1.66212276 |
38 | * MP0000716_abnormal_immune_system | 1.65537776 |
39 | MP0001873_stomach_inflammation | 1.64033599 |
40 | MP0001501_abnormal_sleep_pattern | 1.63728312 |
41 | MP0004947_skin_inflammation | 1.63641702 |
42 | MP0002396_abnormal_hematopoietic_system | 1.61759852 |
43 | * MP0001845_abnormal_inflammatory_respons | 1.60910762 |
44 | MP0003183_abnormal_peptide_metabolism | 1.60672628 |
45 | MP0000343_altered_response_to | 1.58726353 |
46 | MP0005174_abnormal_tail_pigmentation | 1.57371741 |
47 | MP0009333_abnormal_splenocyte_physiolog | 1.56100278 |
48 | MP0002998_abnormal_bone_remodeling | 1.55838837 |
49 | MP0010155_abnormal_intestine_physiology | 1.54852603 |
50 | MP0002139_abnormal_hepatobiliary_system | 1.53092363 |
51 | MP0000689_abnormal_spleen_morphology | 1.51508700 |
52 | MP0000372_irregular_coat_pigmentation | 1.50411695 |
53 | MP0001851_eye_inflammation | 1.45371387 |
54 | MP0002722_abnormal_immune_system | 1.44708500 |
55 | MP0008469_abnormal_protein_level | 1.42164026 |
56 | MP0003075_altered_response_to | 1.41796040 |
57 | MP0002332_abnormal_exercise_endurance | 1.41753427 |
58 | MP0002166_altered_tumor_susceptibility | 1.41640269 |
59 | MP0002933_joint_inflammation | 1.40754804 |
60 | MP0002254_reproductive_system_inflammat | 1.37499111 |
61 | MP0009278_abnormal_bone_marrow | 1.34494136 |
62 | * MP0002429_abnormal_blood_cell | 1.32651324 |
63 | MP0003448_altered_tumor_morphology | 1.31783590 |
64 | MP0003566_abnormal_cell_adhesion | 1.31026871 |
65 | MP0008004_abnormal_stomach_pH | 1.27704244 |
66 | MP0003329_amyloid_beta_deposits | 1.23802829 |
67 | MP0003136_yellow_coat_color | 1.22913070 |
68 | MP0000920_abnormal_myelination | 1.22347472 |
69 | MP0002006_tumorigenesis | 1.21813106 |
70 | MP0000015_abnormal_ear_pigmentation | 1.19040916 |
71 | MP0005167_abnormal_blood-brain_barrier | 1.18853789 |
72 | MP0009764_decreased_sensitivity_to | 1.11756960 |
73 | MP0004808_abnormal_hematopoietic_stem | 1.11143668 |
74 | MP0003646_muscle_fatigue | 1.02956151 |
75 | MP0005166_decreased_susceptibility_to | 1.01140548 |
76 | MP0005397_hematopoietic_system_phenotyp | 1.01044134 |
77 | MP0001545_abnormal_hematopoietic_system | 1.01044134 |
78 | MP0000703_abnormal_thymus_morphology | 1.00885042 |
79 | MP0000604_amyloidosis | 1.00052776 |
80 | MP0005451_abnormal_body_composition | 0.98272224 |
81 | MP0003806_abnormal_nucleotide_metabolis | 0.98227015 |
82 | MP0000858_altered_metastatic_potential | 0.95577014 |
83 | MP0002095_abnormal_skin_pigmentation | 0.94117903 |
84 | MP0003828_pulmonary_edema | 0.93487848 |
85 | MP0002064_seizures | 0.93481347 |
86 | MP0006054_spinal_hemorrhage | 0.89397939 |
87 | MP0003633_abnormal_nervous_system | 0.88974804 |
88 | MP0000249_abnormal_blood_vessel | 0.88597804 |
89 | MP0003279_aneurysm | 0.87505715 |
90 | MP0009763_increased_sensitivity_to | 0.86641846 |
91 | * MP0005390_skeleton_phenotype | 0.86302389 |
92 | MP0005670_abnormal_white_adipose | 0.86301165 |
93 | MP0010307_abnormal_tumor_latency | 0.84147009 |
94 | MP0003453_abnormal_keratinocyte_physiol | 0.83963533 |
95 | MP0003866_abnormal_defecation | 0.83452997 |
96 | MP0005171_absent_coat_pigmentation | 0.83169016 |
97 | MP0005257_abnormal_intraocular_pressure | 0.81105940 |
98 | MP0005023_abnormal_wound_healing | 0.78630213 |
99 | * MP0003795_abnormal_bone_structure | 0.76087688 |
100 | MP0003656_abnormal_erythrocyte_physiolo | 0.76050008 |
101 | MP0002277_abnormal_respiratory_mucosa | 0.75869961 |
102 | MP0005075_abnormal_melanosome_morpholog | 0.74592018 |
103 | MP0009745_abnormal_behavioral_response | 0.73792102 |
104 | MP0000490_abnormal_crypts_of | 0.73635373 |
105 | MP0005535_abnormal_body_temperature | 0.72827913 |
106 | MP0005647_abnormal_sex_gland | 0.72523041 |
107 | MP0002138_abnormal_hepatobiliary_system | 0.70654317 |
108 | MP0001915_intracranial_hemorrhage | 0.70103832 |
109 | MP0009765_abnormal_xenobiotic_induced | 0.69393877 |
110 | MP0004883_abnormal_blood_vessel | 0.69200001 |
111 | MP0001986_abnormal_taste_sensitivity | 0.68456651 |
112 | MP0008438_abnormal_cutaneous_collagen | 0.67788130 |
113 | MP0009046_muscle_twitch | 0.67176387 |
114 | MP0004381_abnormal_hair_follicle | 0.67050718 |
115 | MP0003091_abnormal_cell_migration | 0.66016023 |
116 | MP0003634_abnormal_glial_cell | 0.65818530 |
117 | MP0003631_nervous_system_phenotype | 0.65812238 |
118 | MP0003632_abnormal_nervous_system | 0.65082282 |
119 | MP0001968_abnormal_touch/_nociception | 0.64085376 |
120 | MP0000767_abnormal_smooth_muscle | 0.63972394 |
121 | MP0008874_decreased_physiological_sensi | 0.63376375 |
122 | MP0004885_abnormal_endolymph | 0.63271188 |
123 | MP0001324_abnormal_eye_pigmentation | 0.62825561 |
124 | MP0002693_abnormal_pancreas_physiology | 0.62705092 |
125 | MP0000371_diluted_coat_color | 0.62681997 |
126 | MP0002136_abnormal_kidney_physiology | 0.62177457 |
127 | MP0001663_abnormal_digestive_system | 0.61892036 |
128 | MP0005164_abnormal_response_to | 0.61550922 |
129 | MP0005076_abnormal_cell_differentiation | 0.57402961 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Systemic lupus erythematosus (HP:0002725) | 6.21208768 |
2 | Recurrent abscess formation (HP:0002722) | 5.50382505 |
3 | Recurrent bacterial skin infections (HP:0005406) | 5.04043454 |
4 | Eczematoid dermatitis (HP:0000976) | 4.76908085 |
5 | Increased cerebral lipofuscin (HP:0011813) | 4.66590093 |
6 | Glomerulonephritis (HP:0000099) | 4.48075403 |
7 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 4.38132029 |
8 | Myositis (HP:0100614) | 4.06232216 |
9 | Dysostosis multiplex (HP:0000943) | 3.95453548 |
10 | Abnormality of glycolipid metabolism (HP:0010969) | 3.91076102 |
11 | Abnormality of liposaccharide metabolism (HP:0010968) | 3.91076102 |
12 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 3.91076102 |
13 | Vacuolated lymphocytes (HP:0001922) | 3.84601594 |
14 | Neurofibrillary tangles (HP:0002185) | 3.39432761 |
15 | Orchitis (HP:0100796) | 3.38377870 |
16 | Optic neuritis (HP:0100653) | 3.35663254 |
17 | Retrobulbar optic neuritis (HP:0100654) | 3.35663254 |
18 | Pustule (HP:0200039) | 3.33113978 |
19 | Abnormality of macrophages (HP:0004311) | 3.31852907 |
20 | Keratoconjunctivitis (HP:0001096) | 3.29596182 |
21 | Recurrent skin infections (HP:0001581) | 3.23975041 |
22 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.22278301 |
23 | Recurrent fungal infections (HP:0002841) | 3.21297444 |
24 | Petechiae (HP:0000967) | 3.17657831 |
25 | Complement deficiency (HP:0004431) | 3.15116604 |
26 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.00710235 |
27 | Spontaneous hematomas (HP:0007420) | 2.94184953 |
28 | Mediastinal lymphadenopathy (HP:0100721) | 2.92121344 |
29 | Axonal loss (HP:0003447) | 2.90922651 |
30 | Prolonged bleeding time (HP:0003010) | 2.83883705 |
31 | Prostate neoplasm (HP:0100787) | 2.81468512 |
32 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.80798192 |
33 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.80798192 |
34 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.80798192 |
35 | Abnormality of T cell number (HP:0011839) | 2.80534949 |
36 | Obstructive lung disease (HP:0006536) | 2.80285121 |
37 | Chronic obstructive pulmonary disease (HP:0006510) | 2.80285121 |
38 | T lymphocytopenia (HP:0005403) | 2.79935077 |
39 | Abnormality of complement system (HP:0005339) | 2.79004710 |
40 | Cerebral aneurysm (HP:0004944) | 2.78278315 |
41 | Mucopolysacchariduria (HP:0008155) | 2.77533095 |
42 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.77533095 |
43 | Global brain atrophy (HP:0002283) | 2.76302744 |
44 | Gangrene (HP:0100758) | 2.75887512 |
45 | Hematochezia (HP:0002573) | 2.67724769 |
46 | Disinhibition (HP:0000734) | 2.65605350 |
47 | Recurrent viral infections (HP:0004429) | 2.63256646 |
48 | Colitis (HP:0002583) | 2.62737986 |
49 | Albinism (HP:0001022) | 2.62384050 |
50 | Autoimmune hemolytic anemia (HP:0001890) | 2.61423732 |
51 | Stomatitis (HP:0010280) | 2.60731866 |
52 | Chronic otitis media (HP:0000389) | 2.60648103 |
53 | Gastrointestinal infarctions (HP:0005244) | 2.60528492 |
54 | Arterial tortuosity (HP:0005116) | 2.60403636 |
55 | Gingivitis (HP:0000230) | 2.59478620 |
56 | Ocular albinism (HP:0001107) | 2.54957051 |
57 | Agnosia (HP:0010524) | 2.54483275 |
58 | Pulmonary infiltrates (HP:0002113) | 2.54362079 |
59 | Nephritis (HP:0000123) | 2.54154904 |
60 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.53926085 |
61 | Increased IgM level (HP:0003496) | 2.53452610 |
62 | Bilateral sensorineural hearing impairment (HP:0008619) | 2.52848692 |
63 | Periodontitis (HP:0000704) | 2.51883354 |
64 | Myocardial infarction (HP:0001658) | 2.51837133 |
65 | Gingival bleeding (HP:0000225) | 2.50737266 |
66 | Inflammation of the large intestine (HP:0002037) | 2.48405185 |
67 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 2.47766081 |
68 | Polyneuropathy (HP:0001271) | 2.46834387 |
69 | Encephalitis (HP:0002383) | 2.46474465 |
70 | Retinal atrophy (HP:0001105) | 2.45052971 |
71 | Segmental peripheral demyelination/remyelination (HP:0003481) | 2.42474559 |
72 | Recurrent cutaneous fungal infections (HP:0011370) | 2.40685641 |
73 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.40685641 |
74 | Osteolytic defects of the hand bones (HP:0009699) | 2.38143969 |
75 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.38143969 |
76 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.37768040 |
77 | Autoimmune thrombocytopenia (HP:0001973) | 2.36945747 |
78 | Pulmonary embolism (HP:0002204) | 2.36587334 |
79 | Neuronal loss in central nervous system (HP:0002529) | 2.31725327 |
80 | Vasculitis (HP:0002633) | 2.31454361 |
81 | Arterial thrombosis (HP:0004420) | 2.31417052 |
82 | Thick nail (HP:0001805) | 2.30262695 |
83 | Joint swelling (HP:0001386) | 2.29187936 |
84 | Vertigo (HP:0002321) | 2.28847385 |
85 | Apathy (HP:0000741) | 2.27499664 |
86 | Vascular tortuosity (HP:0004948) | 2.26722213 |
87 | Diminished motivation (HP:0000745) | 2.25481789 |
88 | Amyloidosis (HP:0011034) | 2.24762993 |
89 | Leukocytosis (HP:0001974) | 2.24434332 |
90 | Hepatosplenomegaly (HP:0001433) | 2.23723703 |
91 | Purpura (HP:0000979) | 2.23415453 |
92 | Cerebral inclusion bodies (HP:0100314) | 2.23097695 |
93 | Cheilitis (HP:0100825) | 2.22532219 |
94 | Aortic aneurysm (HP:0004942) | 2.22413359 |
95 | Epistaxis (HP:0000421) | 2.21735847 |
96 | Peripheral demyelination (HP:0011096) | 2.21450430 |
97 | Gastrointestinal inflammation (HP:0004386) | 2.21376818 |
98 | Eosinophilia (HP:0001880) | 2.20986998 |
99 | Inappropriate behavior (HP:0000719) | 2.20033977 |
100 | Meningitis (HP:0001287) | 2.19845074 |
101 | Chronic diarrhea (HP:0002028) | 2.19246215 |
102 | Spondylolisthesis (HP:0003302) | 2.18282157 |
103 | Iris hypopigmentation (HP:0007730) | 2.17822077 |
104 | Abnormality of the periventricular white matter (HP:0002518) | 2.17183597 |
105 | Supranuclear gaze palsy (HP:0000605) | 2.16007948 |
106 | IgM deficiency (HP:0002850) | 2.15698094 |
107 | Tetraparesis (HP:0002273) | 2.15538275 |
108 | Abnormality of the pleura (HP:0002103) | 2.15343362 |
109 | Abnormality of the prostate (HP:0008775) | 2.14320876 |
110 | Stomach cancer (HP:0012126) | 2.13552173 |
111 | Memory impairment (HP:0002354) | 2.11444353 |
112 | Anorexia (HP:0002039) | 2.10514292 |
113 | Parakeratosis (HP:0001036) | 2.06418951 |
114 | Keratoconjunctivitis sicca (HP:0001097) | 2.06233694 |
115 | Increased CSF protein (HP:0002922) | 2.04212437 |
116 | Impaired platelet aggregation (HP:0003540) | 2.02445231 |
117 | Abnormal platelet function (HP:0011869) | 2.02445231 |
118 | Disproportionate tall stature (HP:0001519) | 2.01562870 |
119 | Basal ganglia calcification (HP:0002135) | 2.01288363 |
120 | Hemoptysis (HP:0002105) | 1.99893124 |
121 | Urethral obstruction (HP:0000796) | 1.99014901 |
122 | Thoracic kyphosis (HP:0002942) | 1.98876141 |
123 | IgG deficiency (HP:0004315) | 1.98532760 |
124 | Abnormality of T cells (HP:0002843) | 1.96283938 |
125 | Bone pain (HP:0002653) | 1.96189482 |
126 | Episodic fever (HP:0001954) | 1.95059701 |
127 | Chest pain (HP:0100749) | 1.94850513 |
128 | Progressive neurologic deterioration (HP:0002344) | 1.94491301 |
129 | Abnormality of B cell number (HP:0010975) | 1.94335214 |
130 | Increased serum ferritin (HP:0003281) | 1.94248174 |
131 | Loss of speech (HP:0002371) | 1.93311619 |
132 | Abnormality of eosinophils (HP:0001879) | 1.92849977 |
133 | Cellulitis (HP:0100658) | 1.90195264 |
134 | Urticaria (HP:0001025) | 1.89458476 |
135 | Abnormality of binocular vision (HP:0011514) | 1.88865865 |
136 | Diplopia (HP:0000651) | 1.88865865 |
137 | Alopecia of scalp (HP:0002293) | 1.88734639 |
138 | Mutism (HP:0002300) | 1.87085328 |
139 | Clumsiness (HP:0002312) | 1.86559267 |
140 | Hypergammaglobulinemia (HP:0010702) | 1.86182233 |
141 | Abnormality of the endocardium (HP:0004306) | 1.84213047 |
142 | Acne (HP:0001061) | 1.82205956 |
143 | Nuclear cataract (HP:0100018) | 1.80310605 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TGFBR2 | 4.39955109 |
2 | TXK | 4.37771610 |
3 | MAP4K1 | 3.51027712 |
4 | TYK2 | 3.01866899 |
5 | BLK | 2.43773286 |
6 | BMPR2 | 2.40855744 |
7 | IRAK3 | 2.35514832 |
8 | CSF1R | 2.32284529 |
9 | TAOK3 | 2.20528975 |
10 | TBK1 | 2.14427309 |
11 | STK10 | 2.14284136 |
12 | JAK1 | 2.08755697 |
13 | MAP3K14 | 2.04003387 |
14 | ZAP70 | 1.99959195 |
15 | IRAK4 | 1.98342591 |
16 | KIT | 1.97157169 |
17 | RIPK4 | 1.91597324 |
18 | ITK | 1.87073756 |
19 | IKBKE | 1.79315983 |
20 | DDR2 | 1.76980054 |
21 | EPHB1 | 1.73557832 |
22 | MAPK15 | 1.72262344 |
23 | SIK2 | 1.70731529 |
24 | DAPK2 | 1.69550301 |
25 | HCK | 1.65974263 |
26 | CAMK1D | 1.60530848 |
27 | MARK3 | 1.58745815 |
28 | GRK7 | 1.58150244 |
29 | FRK | 1.57961687 |
30 | IKBKB | 1.56968051 |
31 | JAK3 | 1.55311313 |
32 | SIK3 | 1.53425495 |
33 | ACVR1B | 1.48403220 |
34 | SIK1 | 1.47451857 |
35 | LCK | 1.43499809 |
36 | CSK | 1.43103814 |
37 | TAOK2 | 1.39752370 |
38 | EEF2K | 1.36227102 |
39 | MAP3K11 | 1.32942834 |
40 | TYRO3 | 1.26636906 |
41 | CLK1 | 1.26084165 |
42 | TEC | 1.24678475 |
43 | FES | 1.24270469 |
44 | SYK | 1.19381347 |
45 | JAK2 | 1.17652633 |
46 | CAMK1G | 1.16512150 |
47 | BTK | 1.14340755 |
48 | LYN | 1.13924101 |
49 | MAP3K3 | 1.08755504 |
50 | MATK | 1.05348083 |
51 | NEK9 | 1.03286459 |
52 | FGFR4 | 1.01428423 |
53 | MAP3K13 | 0.99108801 |
54 | FGFR3 | 0.98777586 |
55 | IRAK2 | 0.98560012 |
56 | CDC42BPA | 0.98267196 |
57 | MOS | 0.97474711 |
58 | CDK6 | 0.97183789 |
59 | TRPM7 | 0.96352769 |
60 | PAK4 | 0.92237484 |
61 | MAP2K6 | 0.90216934 |
62 | PIM1 | 0.88257080 |
63 | CHUK | 0.88104900 |
64 | MAP3K10 | 0.87942087 |
65 | TAOK1 | 0.87084668 |
66 | FGR | 0.81835487 |
67 | ERN1 | 0.81597324 |
68 | MAP2K3 | 0.80749395 |
69 | PTK6 | 0.79179072 |
70 | MAPK12 | 0.75865319 |
71 | DMPK | 0.75039673 |
72 | MAP3K1 | 0.73954238 |
73 | MAPK7 | 0.70266416 |
74 | PINK1 | 0.69082666 |
75 | BMX | 0.68867428 |
76 | CDK12 | 0.66312167 |
77 | YES1 | 0.65516917 |
78 | NME2 | 0.64384168 |
79 | PIM2 | 0.64038205 |
80 | PRPF4B | 0.63623146 |
81 | PRKAA2 | 0.62947748 |
82 | RIPK1 | 0.60935748 |
83 | IGF1R | 0.60367094 |
84 | STK4 | 0.57703309 |
85 | SGK3 | 0.56922979 |
86 | GSK3A | 0.56064656 |
87 | MAPKAPK2 | 0.54835918 |
88 | MST4 | 0.54309387 |
89 | MAP3K7 | 0.54137202 |
90 | EPHA3 | 0.53927761 |
91 | EGFR | 0.53751556 |
92 | CDK3 | 0.51159892 |
93 | PRKCQ | 0.50942355 |
94 | PKN1 | 0.50089905 |
95 | PDGFRB | 0.49702560 |
96 | TTN | 0.47184104 |
97 | STK3 | 0.46805995 |
98 | EIF2AK2 | 0.46594242 |
99 | PDK2 | 0.45508912 |
100 | SGK2 | 0.45494672 |
101 | GRK6 | 0.45304492 |
102 | NTRK3 | 0.44973492 |
103 | ABL2 | 0.43477398 |
104 | PAK6 | 0.43037044 |
105 | NTRK2 | 0.42879836 |
106 | MAP3K5 | 0.42276656 |
107 | ABL1 | 0.40843951 |
108 | NUAK1 | 0.38068838 |
109 | CAMKK1 | 0.37999091 |
110 | PDK1 | 0.37780688 |
111 | INSR | 0.37607434 |
112 | HIPK2 | 0.37589545 |
113 | PRKCH | 0.37263909 |
114 | CAMK4 | 0.36528546 |
115 | FYN | 0.36423427 |
116 | MAPKAPK5 | 0.36273619 |
117 | PDPK1 | 0.35617060 |
118 | ADRBK2 | 0.34914419 |
119 | MAPK4 | 0.34905069 |
120 | PAK2 | 0.34891643 |
121 | DYRK1B | 0.34702641 |
122 | RPS6KA6 | 0.34299322 |
123 | CAMKK2 | 0.34275094 |
124 | RPS6KA4 | 0.31358077 |
125 | RPS6KL1 | 0.31001943 |
126 | RPS6KC1 | 0.31001943 |
127 | SRC | 0.29719671 |
128 | TNK2 | 0.29006074 |
129 | MAP4K2 | 0.28379056 |
130 | PRKCD | 0.27733807 |
131 | IRAK1 | 0.27156896 |
132 | INSRR | 0.25378314 |
133 | MAPK13 | 0.23120394 |
134 | PRKCZ | 0.22615305 |
135 | MARK2 | 0.20646760 |
136 | STK11 | 0.20257322 |
137 | CAMK2A | 0.19521160 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 3.48212459 |
2 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 2.79629637 |
3 | Other glycan degradation_Homo sapiens_hsa00511 | 2.68051764 |
4 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.59065538 |
5 | Leishmaniasis_Homo sapiens_hsa05140 | 2.42667233 |
6 | Lysosome_Homo sapiens_hsa04142 | 2.29627217 |
7 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.27673058 |
8 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.23117968 |
9 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.20770842 |
10 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 2.00235388 |
11 | Measles_Homo sapiens_hsa05162 | 1.94724250 |
12 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.94533486 |
13 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.85525467 |
14 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.83760457 |
15 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.82722361 |
16 | Pertussis_Homo sapiens_hsa05133 | 1.73282432 |
17 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.71645620 |
18 | Tuberculosis_Homo sapiens_hsa05152 | 1.66272321 |
19 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.64283585 |
20 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.64176531 |
21 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.62757587 |
22 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.60083443 |
23 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.57120280 |
24 | Malaria_Homo sapiens_hsa05144 | 1.56474392 |
25 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.46547745 |
26 | Allograft rejection_Homo sapiens_hsa05330 | 1.44896888 |
27 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.40429711 |
28 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.39492544 |
29 | Asthma_Homo sapiens_hsa05310 | 1.35300956 |
30 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.34476636 |
31 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.34394387 |
32 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.33024076 |
33 | Influenza A_Homo sapiens_hsa05164 | 1.31641526 |
34 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.28005369 |
35 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.27987320 |
36 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.23908077 |
37 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.19818490 |
38 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.16511870 |
39 | Legionellosis_Homo sapiens_hsa05134 | 1.15670849 |
40 | Apoptosis_Homo sapiens_hsa04210 | 1.15588063 |
41 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.13667866 |
42 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.10622018 |
43 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.09390746 |
44 | Hepatitis B_Homo sapiens_hsa05161 | 1.08927182 |
45 | Phagosome_Homo sapiens_hsa04145 | 1.05597397 |
46 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.04171008 |
47 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.03727253 |
48 | Platelet activation_Homo sapiens_hsa04611 | 1.02508377 |
49 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 1.00789552 |
50 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.99743695 |
51 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.99277800 |
52 | ABC transporters_Homo sapiens_hsa02010 | 0.99123027 |
53 | Salmonella infection_Homo sapiens_hsa05132 | 0.96276424 |
54 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.93173870 |
55 | Viral myocarditis_Homo sapiens_hsa05416 | 0.92572725 |
56 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.90751414 |
57 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.87858208 |
58 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.87299274 |
59 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.87040267 |
60 | Prion diseases_Homo sapiens_hsa05020 | 0.86091907 |
61 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.83921959 |
62 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.83600236 |
63 | Shigellosis_Homo sapiens_hsa05131 | 0.83099938 |
64 | Hepatitis C_Homo sapiens_hsa05160 | 0.82399102 |
65 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.81453452 |
66 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.77673318 |
67 | Endocytosis_Homo sapiens_hsa04144 | 0.75181848 |
68 | Amoebiasis_Homo sapiens_hsa05146 | 0.72163523 |
69 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.72025086 |
70 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.71195126 |
71 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.71018514 |
72 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.70421370 |
73 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.65058330 |
74 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.62033815 |
75 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.62012453 |
76 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.61949667 |
77 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.61895736 |
78 | Colorectal cancer_Homo sapiens_hsa05210 | 0.60716487 |
79 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.59133079 |
80 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.53232563 |
81 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.52202793 |
82 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.52104834 |
83 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.52091824 |
84 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.51267991 |
85 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.50853431 |
86 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.50399263 |
87 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.50145174 |
88 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.49676317 |
89 | Morphine addiction_Homo sapiens_hsa05032 | 0.49646880 |
90 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.47609474 |
91 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.45400796 |
92 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.44522756 |
93 | Focal adhesion_Homo sapiens_hsa04510 | 0.44186943 |
94 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.43590524 |
95 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.43034650 |
96 | Adherens junction_Homo sapiens_hsa04520 | 0.42969479 |
97 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.42917721 |
98 | HTLV-I infection_Homo sapiens_hsa05166 | 0.42915891 |
99 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.42292220 |
100 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.41232167 |
101 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.40021150 |
102 | Lysine degradation_Homo sapiens_hsa00310 | 0.38648651 |
103 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.36714357 |
104 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.36625468 |
105 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.36251096 |
106 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.35626481 |
107 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.34989622 |
108 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.34890658 |
109 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.34822807 |
110 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.34588198 |
111 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.33147180 |
112 | Mineral absorption_Homo sapiens_hsa04978 | 0.32695865 |
113 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.32505718 |
114 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.31102958 |
115 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.30378516 |
116 | Renin secretion_Homo sapiens_hsa04924 | 0.29659110 |
117 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.27383789 |
118 | * Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.26916163 |
119 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.25963070 |
120 | GABAergic synapse_Homo sapiens_hsa04727 | 0.25696137 |
121 | Salivary secretion_Homo sapiens_hsa04970 | 0.24357697 |
122 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.24084295 |
123 | Circadian entrainment_Homo sapiens_hsa04713 | 0.23330447 |
124 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.19042578 |
125 | Insulin resistance_Homo sapiens_hsa04931 | 0.17814995 |