

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 6.03848268 |
| 2 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.10511501 |
| 3 | ATP synthesis coupled proton transport (GO:0015986) | 5.10511501 |
| 4 | cytidine metabolic process (GO:0046087) | 4.97090218 |
| 5 | cytidine catabolic process (GO:0006216) | 4.97090218 |
| 6 | cytidine deamination (GO:0009972) | 4.97090218 |
| 7 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.87534794 |
| 8 | ribosomal small subunit assembly (GO:0000028) | 4.84934796 |
| 9 | chaperone-mediated protein transport (GO:0072321) | 4.77441644 |
| 10 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.32161882 |
| 11 | behavioral response to nicotine (GO:0035095) | 4.29488876 |
| 12 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 4.23832366 |
| 13 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.08756342 |
| 14 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.04232663 |
| 15 | NADH dehydrogenase complex assembly (GO:0010257) | 4.04232663 |
| 16 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.04232663 |
| 17 | protein complex biogenesis (GO:0070271) | 4.00784300 |
| 18 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.94197802 |
| 19 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.94197802 |
| 20 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 3.77719460 |
| 21 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:004316 | 3.76355178 |
| 22 | protein neddylation (GO:0045116) | 3.75997542 |
| 23 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.74885534 |
| 24 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.72686542 |
| 25 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.71489789 |
| 26 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.70812932 |
| 27 | atrial cardiac muscle cell action potential (GO:0086014) | 3.67915996 |
| 28 | proteasome assembly (GO:0043248) | 3.67218780 |
| 29 | replication fork processing (GO:0031297) | 3.64656022 |
| 30 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.56869356 |
| 31 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.54060711 |
| 32 | termination of RNA polymerase III transcription (GO:0006386) | 3.54060711 |
| 33 | endoderm formation (GO:0001706) | 3.48324714 |
| 34 | respiratory electron transport chain (GO:0022904) | 3.40499614 |
| 35 | platelet dense granule organization (GO:0060155) | 3.37740605 |
| 36 | electron transport chain (GO:0022900) | 3.36126981 |
| 37 | protein-cofactor linkage (GO:0018065) | 3.31847897 |
| 38 | maturation of SSU-rRNA (GO:0030490) | 3.31662865 |
| 39 | cAMP biosynthetic process (GO:0006171) | 3.30535469 |
| 40 | rRNA catabolic process (GO:0016075) | 3.16180356 |
| 41 | pseudouridine synthesis (GO:0001522) | 3.14040216 |
| 42 | protein deneddylation (GO:0000338) | 3.12525784 |
| 43 | base-excision repair, AP site formation (GO:0006285) | 3.07377224 |
| 44 | cullin deneddylation (GO:0010388) | 3.03190931 |
| 45 | resolution of meiotic recombination intermediates (GO:0000712) | 3.02605304 |
| 46 | tRNA processing (GO:0008033) | 3.00127348 |
| 47 | chromatin remodeling at centromere (GO:0031055) | 2.93805679 |
| 48 | respiratory chain complex IV assembly (GO:0008535) | 2.90987729 |
| 49 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.85231195 |
| 50 | GTP biosynthetic process (GO:0006183) | 2.84717886 |
| 51 | ncRNA 3-end processing (GO:0043628) | 2.84602411 |
| 52 | sequestering of actin monomers (GO:0042989) | 2.83165414 |
| 53 | tachykinin receptor signaling pathway (GO:0007217) | 2.83108609 |
| 54 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.82781108 |
| 55 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.82781108 |
| 56 | interferon-gamma production (GO:0032609) | 2.80630190 |
| 57 | rRNA modification (GO:0000154) | 2.78366962 |
| 58 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.77768663 |
| 59 | anterograde synaptic vesicle transport (GO:0048490) | 2.76888944 |
| 60 | rRNA metabolic process (GO:0016072) | 2.75941614 |
| 61 | hydrogen ion transmembrane transport (GO:1902600) | 2.75739893 |
| 62 | CENP-A containing nucleosome assembly (GO:0034080) | 2.75604395 |
| 63 | ATP biosynthetic process (GO:0006754) | 2.75574171 |
| 64 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 2.75442248 |
| 65 | protein peptidyl-prolyl isomerization (GO:0000413) | 2.74873168 |
| 66 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.74636130 |
| 67 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 2.73983654 |
| 68 | ribosomal large subunit biogenesis (GO:0042273) | 2.73430804 |
| 69 | rRNA processing (GO:0006364) | 2.71387598 |
| 70 | cellular component biogenesis (GO:0044085) | 2.67188043 |
| 71 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.65743251 |
| 72 | synapsis (GO:0007129) | 2.65630556 |
| 73 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.65530624 |
| 74 | translation (GO:0006412) | 2.63515636 |
| 75 | ncRNA catabolic process (GO:0034661) | 2.62534138 |
| 76 | tRNA metabolic process (GO:0006399) | 2.62192091 |
| 77 | translational termination (GO:0006415) | 2.60334432 |
| 78 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.59940328 |
| 79 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.59940328 |
| 80 | cornea development in camera-type eye (GO:0061303) | 2.58962696 |
| 81 | intraciliary transport (GO:0042073) | 2.58788946 |
| 82 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.58419888 |
| 83 | viral transcription (GO:0019083) | 2.58032020 |
| 84 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.57251524 |
| 85 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.56097375 |
| 86 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.56097375 |
| 87 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.56097375 |
| 88 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.55975121 |
| 89 | negative regulation of ligase activity (GO:0051352) | 2.55975121 |
| 90 | translational elongation (GO:0006414) | 2.55614533 |
| 91 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.54759847 |
| 92 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.54759847 |
| 93 | positive regulation of insulin secretion involved in cellular response to glucose stimulus (GO:00357 | 2.54362481 |
| 94 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.52308422 |
| 95 | proton transport (GO:0015992) | 2.51319264 |
| 96 | rRNA methylation (GO:0031167) | 2.49053144 |
| 97 | intracellular protein transmembrane import (GO:0044743) | 2.48100683 |
| 98 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.47541988 |
| 99 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.46977768 |
| 100 | histone exchange (GO:0043486) | 2.46347119 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 5.23962881 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.57884189 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.17257453 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.59082355 |
| 5 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 3.31303800 |
| 6 | VDR_22108803_ChIP-Seq_LS180_Human | 3.20118340 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.17569463 |
| 8 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.72535590 |
| 9 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.60772408 |
| 10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.59385884 |
| 11 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.38688697 |
| 12 | MYC_18940864_ChIP-ChIP_HL60_Human | 2.24051961 |
| 13 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.23521192 |
| 14 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.21302923 |
| 15 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.14547830 |
| 16 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.11595363 |
| 17 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.99853670 |
| 18 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.97746998 |
| 19 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.96377975 |
| 20 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.90676683 |
| 21 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.87607737 |
| 22 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.82955858 |
| 23 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.73129006 |
| 24 | EWS_26573619_Chip-Seq_HEK293_Human | 1.69345094 |
| 25 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.60842569 |
| 26 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.60330376 |
| 27 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.57102171 |
| 28 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.53465819 |
| 29 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.51595150 |
| 30 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.50831647 |
| 31 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.49022232 |
| 32 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.43480972 |
| 33 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.39666709 |
| 34 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.37510903 |
| 35 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.37154403 |
| 36 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.36173567 |
| 37 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.34401002 |
| 38 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.32853277 |
| 39 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.30729384 |
| 40 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.29303972 |
| 41 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.27126202 |
| 42 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.26619688 |
| 43 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.26313315 |
| 44 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.24936036 |
| 45 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.24931736 |
| 46 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.23800858 |
| 47 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.22704742 |
| 48 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.21066268 |
| 49 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.21066268 |
| 50 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.20188412 |
| 51 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.19688891 |
| 52 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.16774074 |
| 53 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.14108793 |
| 54 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.11955698 |
| 55 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.11403514 |
| 56 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.10042262 |
| 57 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.09917932 |
| 58 | NCOR_22424771_ChIP-Seq_293T_Human | 1.09046245 |
| 59 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.07482313 |
| 60 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.06798911 |
| 61 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.05920326 |
| 62 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.04997822 |
| 63 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.04869530 |
| 64 | FUS_26573619_Chip-Seq_HEK293_Human | 1.03772046 |
| 65 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.02777567 |
| 66 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.02142426 |
| 67 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.02138651 |
| 68 | P300_19829295_ChIP-Seq_ESCs_Human | 1.01386353 |
| 69 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.00491645 |
| 70 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.00243351 |
| 71 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.99505924 |
| 72 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.98059241 |
| 73 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.97558203 |
| 74 | AR_20517297_ChIP-Seq_VCAP_Human | 0.97466709 |
| 75 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.97349601 |
| 76 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.96272789 |
| 77 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.95786691 |
| 78 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.95246084 |
| 79 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.95200884 |
| 80 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.95022427 |
| 81 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.94993586 |
| 82 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.94993586 |
| 83 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.94754344 |
| 84 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.94754344 |
| 85 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.94108502 |
| 86 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.93170543 |
| 87 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.92643028 |
| 88 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.91558919 |
| 89 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.91427665 |
| 90 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.91027241 |
| 91 | SOX2_21211035_ChIP-Seq_LN229_Human | 0.90164934 |
| 92 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.89406821 |
| 93 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.88502274 |
| 94 | ERA_21632823_ChIP-Seq_H3396_Human | 0.88087853 |
| 95 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.87283493 |
| 96 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.87162960 |
| 97 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.87139810 |
| 98 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.86960219 |
| 99 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.86543750 |
| 100 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 0.86483553 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0006292_abnormal_olfactory_placode | 3.88063764 |
| 2 | MP0002102_abnormal_ear_morphology | 3.29505178 |
| 3 | MP0000372_irregular_coat_pigmentation | 2.83998284 |
| 4 | MP0002736_abnormal_nociception_after | 2.70491816 |
| 5 | MP0008877_abnormal_DNA_methylation | 2.61365040 |
| 6 | MP0006072_abnormal_retinal_apoptosis | 2.54195271 |
| 7 | MP0008789_abnormal_olfactory_epithelium | 2.39233360 |
| 8 | MP0003786_premature_aging | 2.38006254 |
| 9 | MP0008007_abnormal_cellular_replicative | 2.36780171 |
| 10 | MP0005671_abnormal_response_to | 2.34638404 |
| 11 | MP0003136_yellow_coat_color | 2.32717870 |
| 12 | MP0003890_abnormal_embryonic-extraembry | 2.26555946 |
| 13 | MP0008058_abnormal_DNA_repair | 2.18316520 |
| 14 | MP0001968_abnormal_touch/_nociception | 2.14566444 |
| 15 | MP0005551_abnormal_eye_electrophysiolog | 2.08023637 |
| 16 | MP0004145_abnormal_muscle_electrophysio | 2.05784969 |
| 17 | MP0003787_abnormal_imprinting | 1.98390292 |
| 18 | MP0005499_abnormal_olfactory_system | 1.97727273 |
| 19 | MP0005394_taste/olfaction_phenotype | 1.97727273 |
| 20 | MP0008995_early_reproductive_senescence | 1.86281877 |
| 21 | MP0009379_abnormal_foot_pigmentation | 1.86064253 |
| 22 | MP0002938_white_spotting | 1.81205183 |
| 23 | MP0008872_abnormal_physiological_respon | 1.75879655 |
| 24 | MP0002653_abnormal_ependyma_morphology | 1.75413242 |
| 25 | MP0004142_abnormal_muscle_tone | 1.65837747 |
| 26 | MP0001986_abnormal_taste_sensitivity | 1.63416343 |
| 27 | MP0002837_dystrophic_cardiac_calcinosis | 1.60572535 |
| 28 | MP0001919_abnormal_reproductive_system | 1.55172945 |
| 29 | MP0001293_anophthalmia | 1.51325293 |
| 30 | MP0002095_abnormal_skin_pigmentation | 1.51000430 |
| 31 | MP0005253_abnormal_eye_physiology | 1.48154328 |
| 32 | MP0001727_abnormal_embryo_implantation | 1.47452237 |
| 33 | MP0003878_abnormal_ear_physiology | 1.47402451 |
| 34 | MP0005377_hearing/vestibular/ear_phenot | 1.47402451 |
| 35 | MP0009745_abnormal_behavioral_response | 1.44300479 |
| 36 | MP0004957_abnormal_blastocyst_morpholog | 1.39711210 |
| 37 | MP0000427_abnormal_hair_cycle | 1.37814327 |
| 38 | MP0003718_maternal_effect | 1.36089923 |
| 39 | MP0003011_delayed_dark_adaptation | 1.35548046 |
| 40 | MP0000778_abnormal_nervous_system | 1.32699345 |
| 41 | MP0009780_abnormal_chondrocyte_physiolo | 1.31013517 |
| 42 | MP0001485_abnormal_pinna_reflex | 1.30526989 |
| 43 | MP0002733_abnormal_thermal_nociception | 1.27389218 |
| 44 | MP0004885_abnormal_endolymph | 1.26724842 |
| 45 | MP0002638_abnormal_pupillary_reflex | 1.25754939 |
| 46 | MP0001905_abnormal_dopamine_level | 1.25141084 |
| 47 | MP0002163_abnormal_gland_morphology | 1.16758662 |
| 48 | MP0001984_abnormal_olfaction | 1.16342521 |
| 49 | MP0003693_abnormal_embryo_hatching | 1.13672571 |
| 50 | MP0006276_abnormal_autonomic_nervous | 1.13333811 |
| 51 | MP0002234_abnormal_pharynx_morphology | 1.11322120 |
| 52 | MP0010094_abnormal_chromosome_stability | 1.11300106 |
| 53 | MP0005389_reproductive_system_phenotype | 1.10395357 |
| 54 | MP0003646_muscle_fatigue | 1.09427980 |
| 55 | MP0008875_abnormal_xenobiotic_pharmacok | 1.08881484 |
| 56 | MP0005075_abnormal_melanosome_morpholog | 1.08603843 |
| 57 | MP0009046_muscle_twitch | 1.06378176 |
| 58 | MP0002557_abnormal_social/conspecific_i | 1.06238334 |
| 59 | MP0002272_abnormal_nervous_system | 1.05953114 |
| 60 | MP0006035_abnormal_mitochondrial_morpho | 1.04982938 |
| 61 | MP0000631_abnormal_neuroendocrine_gland | 1.04074997 |
| 62 | MP0005195_abnormal_posterior_eye | 1.02896907 |
| 63 | MP0002572_abnormal_emotion/affect_behav | 1.00997210 |
| 64 | MP0005423_abnormal_somatic_nervous | 1.00187102 |
| 65 | MP0003121_genomic_imprinting | 0.99902290 |
| 66 | MP0001970_abnormal_pain_threshold | 0.99083575 |
| 67 | MP0006036_abnormal_mitochondrial_physio | 0.98506652 |
| 68 | MP0005174_abnormal_tail_pigmentation | 0.98464172 |
| 69 | MP0008775_abnormal_heart_ventricle | 0.97753038 |
| 70 | MP0001486_abnormal_startle_reflex | 0.93870822 |
| 71 | MP0005084_abnormal_gallbladder_morpholo | 0.93687820 |
| 72 | MP0003186_abnormal_redox_activity | 0.91828345 |
| 73 | MP0003123_paternal_imprinting | 0.91466481 |
| 74 | MP0002751_abnormal_autonomic_nervous | 0.90573306 |
| 75 | MP0005645_abnormal_hypothalamus_physiol | 0.90460322 |
| 76 | MP0002067_abnormal_sensory_capabilities | 0.89755628 |
| 77 | MP0001529_abnormal_vocalization | 0.88087048 |
| 78 | MP0004742_abnormal_vestibular_system | 0.87872403 |
| 79 | MP0000955_abnormal_spinal_cord | 0.86969753 |
| 80 | MP0003195_calcinosis | 0.86631269 |
| 81 | MP0002752_abnormal_somatic_nervous | 0.85065564 |
| 82 | MP0002064_seizures | 0.80738315 |
| 83 | MP0005391_vision/eye_phenotype | 0.79666274 |
| 84 | MP0003635_abnormal_synaptic_transmissio | 0.78007476 |
| 85 | MP0001835_abnormal_antigen_presentation | 0.75918559 |
| 86 | MP0003111_abnormal_nucleus_morphology | 0.75761311 |
| 87 | MP0001440_abnormal_grooming_behavior | 0.75276458 |
| 88 | MP0005408_hypopigmentation | 0.73761078 |
| 89 | MP0003183_abnormal_peptide_metabolism | 0.72948348 |
| 90 | MP0004215_abnormal_myocardial_fiber | 0.72887822 |
| 91 | MP0002277_abnormal_respiratory_mucosa | 0.72783093 |
| 92 | MP0001963_abnormal_hearing_physiology | 0.71392864 |
| 93 | MP0005379_endocrine/exocrine_gland_phen | 0.69788495 |
| 94 | MP0003567_abnormal_fetal_cardiomyocyte | 0.68968703 |
| 95 | MP0000647_abnormal_sebaceous_gland | 0.68225680 |
| 96 | MP0003122_maternal_imprinting | 0.66753938 |
| 97 | MP0005410_abnormal_fertilization | 0.66597542 |
| 98 | MP0002063_abnormal_learning/memory/cond | 0.66384508 |
| 99 | MP0003137_abnormal_impulse_conducting | 0.66310734 |
| 100 | MP0001119_abnormal_female_reproductive | 0.66090419 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.59172166 |
| 2 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.16327233 |
| 3 | Congenital stationary night blindness (HP:0007642) | 3.98494141 |
| 4 | Mitochondrial inheritance (HP:0001427) | 3.89442498 |
| 5 | Progressive macrocephaly (HP:0004481) | 3.84693990 |
| 6 | Acute encephalopathy (HP:0006846) | 3.81984263 |
| 7 | Increased CSF lactate (HP:0002490) | 3.74462098 |
| 8 | Hepatocellular necrosis (HP:0001404) | 3.68491221 |
| 9 | Pancreatic fibrosis (HP:0100732) | 3.53757675 |
| 10 | Myokymia (HP:0002411) | 3.27912685 |
| 11 | Colon cancer (HP:0003003) | 3.23301946 |
| 12 | Hepatic necrosis (HP:0002605) | 3.05700654 |
| 13 | Abnormality of the labia minora (HP:0012880) | 2.95072030 |
| 14 | Cerebral edema (HP:0002181) | 2.91080895 |
| 15 | Pancreatic cysts (HP:0001737) | 2.85559257 |
| 16 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.84885902 |
| 17 | Increased hepatocellular lipid droplets (HP:0006565) | 2.83632638 |
| 18 | Nephronophthisis (HP:0000090) | 2.81867380 |
| 19 | Abnormal number of erythroid precursors (HP:0012131) | 2.78907779 |
| 20 | IgG deficiency (HP:0004315) | 2.72850789 |
| 21 | Lipid accumulation in hepatocytes (HP:0006561) | 2.66762657 |
| 22 | Abnormality of magnesium homeostasis (HP:0004921) | 2.66534299 |
| 23 | Reticulocytopenia (HP:0001896) | 2.65967969 |
| 24 | Optic disc pallor (HP:0000543) | 2.65463148 |
| 25 | Abnormality of the renal cortex (HP:0011035) | 2.65161230 |
| 26 | Aplastic anemia (HP:0001915) | 2.51644112 |
| 27 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.48389368 |
| 28 | Abnormality of alanine metabolism (HP:0010916) | 2.48389368 |
| 29 | Hyperalaninemia (HP:0003348) | 2.48389368 |
| 30 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.48229852 |
| 31 | Increased serum lactate (HP:0002151) | 2.47384556 |
| 32 | Renal Fanconi syndrome (HP:0001994) | 2.44828800 |
| 33 | Abnormality of midbrain morphology (HP:0002418) | 2.42526670 |
| 34 | Molar tooth sign on MRI (HP:0002419) | 2.42526670 |
| 35 | Supernumerary spleens (HP:0009799) | 2.42299138 |
| 36 | True hermaphroditism (HP:0010459) | 2.42296014 |
| 37 | Pendular nystagmus (HP:0012043) | 2.42236661 |
| 38 | Tubular atrophy (HP:0000092) | 2.41776533 |
| 39 | Congenital, generalized hypertrichosis (HP:0004540) | 2.39401419 |
| 40 | Cerebral hypomyelination (HP:0006808) | 2.31758832 |
| 41 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.29585548 |
| 42 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.29585548 |
| 43 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.26866833 |
| 44 | Type II lissencephaly (HP:0007260) | 2.26711215 |
| 45 | Abolished electroretinogram (ERG) (HP:0000550) | 2.25934020 |
| 46 | Abnormal drinking behavior (HP:0030082) | 2.24173033 |
| 47 | Polydipsia (HP:0001959) | 2.24173033 |
| 48 | Abnormality of the renal medulla (HP:0100957) | 2.23796348 |
| 49 | Polyuria (HP:0000103) | 2.19923793 |
| 50 | Progressive microcephaly (HP:0000253) | 2.17400726 |
| 51 | Lactic acidosis (HP:0003128) | 2.16508458 |
| 52 | Macrocytic anemia (HP:0001972) | 2.16309173 |
| 53 | Absent septum pellucidum (HP:0001331) | 2.14533367 |
| 54 | Septo-optic dysplasia (HP:0100842) | 2.12704901 |
| 55 | Respiratory failure (HP:0002878) | 2.11510137 |
| 56 | 3-Methylglutaconic aciduria (HP:0003535) | 2.10328054 |
| 57 | Leukodystrophy (HP:0002415) | 2.09629635 |
| 58 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.07438172 |
| 59 | Stenosis of the external auditory canal (HP:0000402) | 2.06326043 |
| 60 | Palpebral edema (HP:0100540) | 2.03830011 |
| 61 | Increased intramyocellular lipid droplets (HP:0012240) | 2.02609430 |
| 62 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.01072051 |
| 63 | Severe visual impairment (HP:0001141) | 1.99443068 |
| 64 | Constricted visual fields (HP:0001133) | 1.99179271 |
| 65 | Exercise intolerance (HP:0003546) | 1.98344382 |
| 66 | Methylmalonic acidemia (HP:0002912) | 1.96382443 |
| 67 | Abnormal hemoglobin (HP:0011902) | 1.96112094 |
| 68 | Congenital hepatic fibrosis (HP:0002612) | 1.95295002 |
| 69 | Oligodactyly (hands) (HP:0001180) | 1.92993469 |
| 70 | Lethargy (HP:0001254) | 1.92346916 |
| 71 | Adactyly (HP:0009776) | 1.92251723 |
| 72 | Abnormality of the septum pellucidum (HP:0007375) | 1.92058453 |
| 73 | Hypoproteinemia (HP:0003075) | 1.90446346 |
| 74 | Hypomagnesemia (HP:0002917) | 1.89172838 |
| 75 | Sclerocornea (HP:0000647) | 1.87590883 |
| 76 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.87588387 |
| 77 | Delayed CNS myelination (HP:0002188) | 1.87198340 |
| 78 | Methylmalonic aciduria (HP:0012120) | 1.86258540 |
| 79 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.85984698 |
| 80 | Hypoplasia of the uterus (HP:0000013) | 1.85380324 |
| 81 | Blindness (HP:0000618) | 1.83794188 |
| 82 | Dyschromatopsia (HP:0007641) | 1.83459291 |
| 83 | Fibular aplasia (HP:0002990) | 1.83436727 |
| 84 | Respiratory difficulties (HP:0002880) | 1.81469235 |
| 85 | Exertional dyspnea (HP:0002875) | 1.80589980 |
| 86 | CNS demyelination (HP:0007305) | 1.80544475 |
| 87 | T lymphocytopenia (HP:0005403) | 1.80459924 |
| 88 | Hypoplasia of the pons (HP:0012110) | 1.80191229 |
| 89 | Global brain atrophy (HP:0002283) | 1.78732998 |
| 90 | Prominent metopic ridge (HP:0005487) | 1.78470086 |
| 91 | Entropion (HP:0000621) | 1.77708807 |
| 92 | Furrowed tongue (HP:0000221) | 1.75727840 |
| 93 | Abnormality of the pons (HP:0007361) | 1.73781740 |
| 94 | Postaxial foot polydactyly (HP:0001830) | 1.73382167 |
| 95 | Cerebellar dysplasia (HP:0007033) | 1.72549666 |
| 96 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.70970869 |
| 97 | Abnormal urine output (HP:0012590) | 1.68444935 |
| 98 | X-linked dominant inheritance (HP:0001423) | 1.68248175 |
| 99 | Type 2 muscle fiber atrophy (HP:0003554) | 1.66312714 |
| 100 | Abnormality of T cell number (HP:0011839) | 1.65886957 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | NUAK1 | 3.47890568 |
| 2 | MAP3K11 | 3.16773307 |
| 3 | VRK2 | 3.08227090 |
| 4 | TXK | 2.95445641 |
| 5 | WNK4 | 2.60373200 |
| 6 | LATS1 | 2.48102448 |
| 7 | STK16 | 2.47239241 |
| 8 | ADRBK2 | 2.36154992 |
| 9 | MAP2K6 | 2.09913895 |
| 10 | NEK1 | 2.00748592 |
| 11 | BUB1 | 1.95421759 |
| 12 | FRK | 1.85939291 |
| 13 | CDC7 | 1.81947153 |
| 14 | MKNK2 | 1.80912156 |
| 15 | EIF2AK3 | 1.77383001 |
| 16 | DYRK2 | 1.74844197 |
| 17 | TNIK | 1.64872474 |
| 18 | TAOK3 | 1.62119474 |
| 19 | TRIM28 | 1.59569382 |
| 20 | ICK | 1.58104004 |
| 21 | GRK1 | 1.55493958 |
| 22 | MST4 | 1.50008660 |
| 23 | BMPR1B | 1.47115921 |
| 24 | VRK1 | 1.43846699 |
| 25 | WNK3 | 1.39436969 |
| 26 | OXSR1 | 1.35214677 |
| 27 | PLK3 | 1.30959778 |
| 28 | NTRK3 | 1.28459314 |
| 29 | STK39 | 1.25658597 |
| 30 | ZAK | 1.24560412 |
| 31 | ITK | 1.21842147 |
| 32 | MAP3K9 | 1.21136398 |
| 33 | ALK | 1.12858530 |
| 34 | PBK | 1.10835692 |
| 35 | ACVR1B | 1.10478166 |
| 36 | CAMKK2 | 1.10323202 |
| 37 | PRKCG | 1.09684316 |
| 38 | EIF2AK1 | 1.08409525 |
| 39 | TAF1 | 1.07317602 |
| 40 | PLK2 | 1.04985083 |
| 41 | MARK1 | 1.04582810 |
| 42 | PDK2 | 1.01409739 |
| 43 | MAP4K1 | 0.97966183 |
| 44 | STK3 | 0.97400983 |
| 45 | TSSK6 | 0.96431036 |
| 46 | MKNK1 | 0.95839614 |
| 47 | MINK1 | 0.95717080 |
| 48 | MAP4K2 | 0.94074930 |
| 49 | SRPK1 | 0.91796587 |
| 50 | MAP3K12 | 0.87764340 |
| 51 | CSNK1G1 | 0.87685552 |
| 52 | NME1 | 0.87080666 |
| 53 | SCYL2 | 0.84655240 |
| 54 | PRKCQ | 0.83401000 |
| 55 | IKBKE | 0.81320638 |
| 56 | PLK4 | 0.79098753 |
| 57 | NEK2 | 0.78090718 |
| 58 | CSNK1G3 | 0.77535045 |
| 59 | IKBKB | 0.77130865 |
| 60 | BRSK2 | 0.76048803 |
| 61 | BCKDK | 0.74117383 |
| 62 | PRKCI | 0.73035718 |
| 63 | EIF2AK2 | 0.72708189 |
| 64 | AURKA | 0.71150040 |
| 65 | CSNK1G2 | 0.69174644 |
| 66 | TEC | 0.67801553 |
| 67 | PHKG2 | 0.67161101 |
| 68 | PHKG1 | 0.67161101 |
| 69 | ADRBK1 | 0.66535957 |
| 70 | PLK1 | 0.65641439 |
| 71 | AURKB | 0.61798210 |
| 72 | STK4 | 0.56826912 |
| 73 | NLK | 0.56331049 |
| 74 | TLK1 | 0.54346453 |
| 75 | MAPK15 | 0.54204277 |
| 76 | INSRR | 0.52130416 |
| 77 | CSF1R | 0.48673933 |
| 78 | BTK | 0.48353638 |
| 79 | DAPK1 | 0.48310322 |
| 80 | PINK1 | 0.47740918 |
| 81 | CHEK2 | 0.44203919 |
| 82 | CSNK2A2 | 0.42310863 |
| 83 | CDK19 | 0.41027718 |
| 84 | CASK | 0.40728808 |
| 85 | PRKCD | 0.40612848 |
| 86 | PIK3CA | 0.40183802 |
| 87 | DYRK1A | 0.39038545 |
| 88 | SYK | 0.38367891 |
| 89 | CSNK1E | 0.37922755 |
| 90 | CSNK1A1 | 0.37476689 |
| 91 | LCK | 0.37345247 |
| 92 | PRKCA | 0.37259092 |
| 93 | PRKCE | 0.36972014 |
| 94 | TYRO3 | 0.36820524 |
| 95 | LYN | 0.36705344 |
| 96 | PIK3CG | 0.35683086 |
| 97 | CSNK1A1L | 0.34698960 |
| 98 | PRKG1 | 0.34195415 |
| 99 | PRKACA | 0.34063442 |
| 100 | CSNK2A1 | 0.33914180 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.84646626 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 3.84491956 |
| 3 | Ribosome_Homo sapiens_hsa03010 | 3.48141802 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.25426526 |
| 5 | RNA polymerase_Homo sapiens_hsa03020 | 2.90927970 |
| 6 | Huntingtons disease_Homo sapiens_hsa05016 | 2.37060165 |
| 7 | Alzheimers disease_Homo sapiens_hsa05010 | 2.18191971 |
| 8 | Caffeine metabolism_Homo sapiens_hsa00232 | 2.07305330 |
| 9 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.05610048 |
| 10 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.03573884 |
| 11 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.93539250 |
| 12 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.92405815 |
| 13 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.91923225 |
| 14 | Protein export_Homo sapiens_hsa03060 | 1.90950292 |
| 15 | Homologous recombination_Homo sapiens_hsa03440 | 1.87822314 |
| 16 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.79632468 |
| 17 | RNA degradation_Homo sapiens_hsa03018 | 1.64567893 |
| 18 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.62325006 |
| 19 | Mismatch repair_Homo sapiens_hsa03430 | 1.53952499 |
| 20 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.53646602 |
| 21 | Basal transcription factors_Homo sapiens_hsa03022 | 1.51706158 |
| 22 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.47618965 |
| 23 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.47544959 |
| 24 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.42463192 |
| 25 | Spliceosome_Homo sapiens_hsa03040 | 1.39966711 |
| 26 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.39949022 |
| 27 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.35143223 |
| 28 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.30657148 |
| 29 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.30651147 |
| 30 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.30049767 |
| 31 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.29648088 |
| 32 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 1.21883737 |
| 33 | Peroxisome_Homo sapiens_hsa04146 | 1.18658716 |
| 34 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.18122936 |
| 35 | DNA replication_Homo sapiens_hsa03030 | 1.16230780 |
| 36 | RNA transport_Homo sapiens_hsa03013 | 1.13374562 |
| 37 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.13187656 |
| 38 | Purine metabolism_Homo sapiens_hsa00230 | 1.12917562 |
| 39 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.12189650 |
| 40 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.09920573 |
| 41 | Base excision repair_Homo sapiens_hsa03410 | 1.05464025 |
| 42 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.04556101 |
| 43 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.00624598 |
| 44 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.99774082 |
| 45 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.99591075 |
| 46 | Morphine addiction_Homo sapiens_hsa05032 | 0.94569959 |
| 47 | Nicotine addiction_Homo sapiens_hsa05033 | 0.89715073 |
| 48 | Phototransduction_Homo sapiens_hsa04744 | 0.85832033 |
| 49 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.83578900 |
| 50 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.81753226 |
| 51 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.80598421 |
| 52 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.80553462 |
| 53 | Circadian entrainment_Homo sapiens_hsa04713 | 0.76886459 |
| 54 | GABAergic synapse_Homo sapiens_hsa04727 | 0.72750616 |
| 55 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.72714316 |
| 56 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.70140398 |
| 57 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.70091259 |
| 58 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.69888748 |
| 59 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.68014263 |
| 60 | Asthma_Homo sapiens_hsa05310 | 0.67898057 |
| 61 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.67040789 |
| 62 | Retinol metabolism_Homo sapiens_hsa00830 | 0.66602267 |
| 63 | Salivary secretion_Homo sapiens_hsa04970 | 0.65885642 |
| 64 | Insulin secretion_Homo sapiens_hsa04911 | 0.64388171 |
| 65 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.63851140 |
| 66 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.61833521 |
| 67 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.61801447 |
| 68 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.60519272 |
| 69 | Olfactory transduction_Homo sapiens_hsa04740 | 0.59883117 |
| 70 | Allograft rejection_Homo sapiens_hsa05330 | 0.59100352 |
| 71 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.57459059 |
| 72 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.57360991 |
| 73 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.57014529 |
| 74 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.56100743 |
| 75 | Metabolic pathways_Homo sapiens_hsa01100 | 0.56051737 |
| 76 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.52108764 |
| 77 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.51042474 |
| 78 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.50743088 |
| 79 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.48057721 |
| 80 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.46078528 |
| 81 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.45883395 |
| 82 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.45461303 |
| 83 | Sulfur relay system_Homo sapiens_hsa04122 | 0.44381252 |
| 84 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.42278013 |
| 85 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.41873644 |
| 86 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.40928064 |
| 87 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.40478724 |
| 88 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.40238294 |
| 89 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.39990526 |
| 90 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.39611898 |
| 91 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.38528114 |
| 92 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.38515683 |
| 93 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.37856643 |
| 94 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.34961760 |
| 95 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.33378215 |
| 96 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.30960337 |
| 97 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.30927256 |
| 98 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.29978275 |
| 99 | Taste transduction_Homo sapiens_hsa04742 | 0.29799491 |
| 100 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.28552458 |

