

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 6.27576223 |
| 2 | maturation of SSU-rRNA (GO:0030490) | 5.55620487 |
| 3 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.38132384 |
| 4 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 5.25849334 |
| 5 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.06836862 |
| 6 | ATP synthesis coupled proton transport (GO:0015986) | 5.06836862 |
| 7 | regulation of cellular respiration (GO:0043457) | 5.05306089 |
| 8 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.95984634 |
| 9 | cytidine deamination (GO:0009972) | 4.85012869 |
| 10 | cytidine metabolic process (GO:0046087) | 4.85012869 |
| 11 | cytidine catabolic process (GO:0006216) | 4.85012869 |
| 12 | nucleobase biosynthetic process (GO:0046112) | 4.64740372 |
| 13 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.53917579 |
| 14 | respiratory electron transport chain (GO:0022904) | 4.41898401 |
| 15 | chromatin remodeling at centromere (GO:0031055) | 4.41534657 |
| 16 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.39430171 |
| 17 | electron transport chain (GO:0022900) | 4.37755094 |
| 18 | CENP-A containing nucleosome assembly (GO:0034080) | 4.30919242 |
| 19 | purine nucleotide salvage (GO:0032261) | 4.28642462 |
| 20 | purine nucleobase biosynthetic process (GO:0009113) | 4.26417109 |
| 21 | ribosomal small subunit biogenesis (GO:0042274) | 4.23037448 |
| 22 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.00191214 |
| 23 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.99002616 |
| 24 | protein deneddylation (GO:0000338) | 3.93481624 |
| 25 | cullin deneddylation (GO:0010388) | 3.91459462 |
| 26 | chaperone-mediated protein transport (GO:0072321) | 3.90319993 |
| 27 | DNA replication checkpoint (GO:0000076) | 3.90241289 |
| 28 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.88943793 |
| 29 | kinetochore assembly (GO:0051382) | 3.86061345 |
| 30 | postreplication repair (GO:0006301) | 3.81209671 |
| 31 | DNA strand elongation (GO:0022616) | 3.80045580 |
| 32 | ribosomal large subunit biogenesis (GO:0042273) | 3.77769726 |
| 33 | translesion synthesis (GO:0019985) | 3.68261546 |
| 34 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 3.62536767 |
| 35 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 3.62070841 |
| 36 | protein neddylation (GO:0045116) | 3.53724283 |
| 37 | negative regulation of telomere maintenance (GO:0032205) | 3.52268628 |
| 38 | purine deoxyribonucleotide catabolic process (GO:0009155) | 3.51031274 |
| 39 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.50264847 |
| 40 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.50264847 |
| 41 | rRNA modification (GO:0000154) | 3.45128237 |
| 42 | histone exchange (GO:0043486) | 3.41641584 |
| 43 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 3.36280476 |
| 44 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.35455008 |
| 45 | mannosylation (GO:0097502) | 3.33428752 |
| 46 | adenosine metabolic process (GO:0046085) | 3.33213836 |
| 47 | viral transcription (GO:0019083) | 3.32128040 |
| 48 | translational termination (GO:0006415) | 3.27573728 |
| 49 | ribosomal small subunit assembly (GO:0000028) | 3.27525069 |
| 50 | protein-cofactor linkage (GO:0018065) | 3.27473901 |
| 51 | succinate metabolic process (GO:0006105) | 3.25077558 |
| 52 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.24475919 |
| 53 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.18775053 |
| 54 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.18775053 |
| 55 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.17199219 |
| 56 | translational elongation (GO:0006414) | 3.14554906 |
| 57 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.14141941 |
| 58 | NADH dehydrogenase complex assembly (GO:0010257) | 3.14141941 |
| 59 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.14141941 |
| 60 | transcription from mitochondrial promoter (GO:0006390) | 3.12112002 |
| 61 | hydrogen ion transmembrane transport (GO:1902600) | 3.08489843 |
| 62 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.08417546 |
| 63 | pseudouridine synthesis (GO:0001522) | 3.07886142 |
| 64 | deoxyribonucleotide catabolic process (GO:0009264) | 3.05953252 |
| 65 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.05215242 |
| 66 | translation (GO:0006412) | 3.04537832 |
| 67 | telomere maintenance via recombination (GO:0000722) | 3.04226324 |
| 68 | kinetochore organization (GO:0051383) | 3.02613201 |
| 69 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.01817211 |
| 70 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.01817211 |
| 71 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.01566185 |
| 72 | DNA replication-independent nucleosome organization (GO:0034724) | 3.01566185 |
| 73 | purine-containing compound salvage (GO:0043101) | 2.99965100 |
| 74 | ubiquinone biosynthetic process (GO:0006744) | 2.99462286 |
| 75 | tricarboxylic acid cycle (GO:0006099) | 2.96796726 |
| 76 | platelet dense granule organization (GO:0060155) | 2.95382172 |
| 77 | adaptation of signaling pathway (GO:0023058) | 2.93883946 |
| 78 | tongue development (GO:0043586) | 2.92906014 |
| 79 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.92891688 |
| 80 | telomere maintenance via telomere lengthening (GO:0010833) | 2.92334508 |
| 81 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.91992228 |
| 82 | deoxyribose phosphate catabolic process (GO:0046386) | 2.91935797 |
| 83 | positive regulation of uterine smooth muscle contraction (GO:0070474) | 2.90772315 |
| 84 | piRNA metabolic process (GO:0034587) | 2.90384038 |
| 85 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 2.89829715 |
| 86 | deoxyribonucleotide biosynthetic process (GO:0009263) | 2.89224825 |
| 87 | tolerance induction (GO:0002507) | 2.89034443 |
| 88 | oxidative phosphorylation (GO:0006119) | 2.88481978 |
| 89 | protein complex biogenesis (GO:0070271) | 2.88157833 |
| 90 | protein targeting to ER (GO:0045047) | 2.87022214 |
| 91 | cotranslational protein targeting to membrane (GO:0006613) | 2.84889824 |
| 92 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.84088660 |
| 93 | proteasome assembly (GO:0043248) | 2.84003312 |
| 94 | GTP biosynthetic process (GO:0006183) | 2.83350255 |
| 95 | aerobic respiration (GO:0009060) | 2.83125547 |
| 96 | respiratory chain complex IV assembly (GO:0008535) | 2.83010279 |
| 97 | inner mitochondrial membrane organization (GO:0007007) | 2.82460878 |
| 98 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.82456865 |
| 99 | male meiosis I (GO:0007141) | 2.82078564 |
| 100 | AMP metabolic process (GO:0046033) | 2.81253095 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.51274640 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.51517246 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.23014829 |
| 4 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.17913740 |
| 5 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.95762201 |
| 6 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.93378614 |
| 7 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.64161420 |
| 8 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.52086094 |
| 9 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.47182931 |
| 10 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.46268644 |
| 11 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.45984497 |
| 12 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.45972547 |
| 13 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.44439059 |
| 14 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.23229371 |
| 15 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.13078028 |
| 16 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.07801998 |
| 17 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.00166987 |
| 18 | E2F7_22180533_ChIP-Seq_HELA_Human | 11.9342598 |
| 19 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.99492218 |
| 20 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.93204070 |
| 21 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.92651077 |
| 22 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.89784622 |
| 23 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.89638246 |
| 24 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.84556250 |
| 25 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.83005106 |
| 26 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.82355278 |
| 27 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.81861601 |
| 28 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.79109375 |
| 29 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.72544353 |
| 30 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.68271299 |
| 31 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.66848413 |
| 32 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.64236657 |
| 33 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.60880723 |
| 34 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.56471992 |
| 35 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.55901544 |
| 36 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.53821394 |
| 37 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.53179436 |
| 38 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.52296942 |
| 39 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.49635629 |
| 40 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.44660702 |
| 41 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.44660702 |
| 42 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.44660702 |
| 43 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.44100282 |
| 44 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.43364342 |
| 45 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.41165041 |
| 46 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.38959880 |
| 47 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.31501264 |
| 48 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.30291495 |
| 49 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.26930732 |
| 50 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.24642931 |
| 51 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.24137325 |
| 52 | EWS_26573619_Chip-Seq_HEK293_Human | 1.23701181 |
| 53 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.20043043 |
| 54 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.19933093 |
| 55 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.18658166 |
| 56 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.16599603 |
| 57 | FUS_26573619_Chip-Seq_HEK293_Human | 1.14927695 |
| 58 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.11891067 |
| 59 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.10791016 |
| 60 | VDR_22108803_ChIP-Seq_LS180_Human | 1.10765094 |
| 61 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.07874945 |
| 62 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.06867190 |
| 63 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.04329289 |
| 64 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.99703879 |
| 65 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.98705175 |
| 66 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.98057418 |
| 67 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.96791391 |
| 68 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.95726798 |
| 69 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.95561929 |
| 70 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 0.93542777 |
| 71 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.93026697 |
| 72 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.89811551 |
| 73 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.86526500 |
| 74 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.86423898 |
| 75 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 0.85643891 |
| 76 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.84094240 |
| 77 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.83859475 |
| 78 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.83859475 |
| 79 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.80692037 |
| 80 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.80139507 |
| 81 | P300_19829295_ChIP-Seq_ESCs_Human | 0.80101605 |
| 82 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.79621536 |
| 83 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.79075800 |
| 84 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.77815766 |
| 85 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.77028853 |
| 86 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 0.76226250 |
| 87 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.75414623 |
| 88 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.75124853 |
| 89 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.75124853 |
| 90 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.71516454 |
| 91 | NCOR_22424771_ChIP-Seq_293T_Human | 0.71018867 |
| 92 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.70783647 |
| 93 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.70069076 |
| 94 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.69178664 |
| 95 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.68484723 |
| 96 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.67985272 |
| 97 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.67849449 |
| 98 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.67781931 |
| 99 | AR_20517297_ChIP-Seq_VCAP_Human | 0.67318239 |
| 100 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.67316231 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 5.17474792 |
| 2 | MP0006292_abnormal_olfactory_placode | 3.69788610 |
| 3 | MP0008058_abnormal_DNA_repair | 3.60095288 |
| 4 | MP0001346_abnormal_lacrimal_gland | 3.57665947 |
| 5 | MP0009697_abnormal_copulation | 3.30213403 |
| 6 | MP0010094_abnormal_chromosome_stability | 2.52939756 |
| 7 | MP0004957_abnormal_blastocyst_morpholog | 2.50003972 |
| 8 | MP0003806_abnormal_nucleotide_metabolis | 2.45250765 |
| 9 | MP0008007_abnormal_cellular_replicative | 2.41515758 |
| 10 | MP0003693_abnormal_embryo_hatching | 2.38002687 |
| 11 | MP0005408_hypopigmentation | 2.35622553 |
| 12 | MP0005075_abnormal_melanosome_morpholog | 2.19640273 |
| 13 | MP0008789_abnormal_olfactory_epithelium | 2.18428572 |
| 14 | MP0001293_anophthalmia | 2.06896625 |
| 15 | MP0002736_abnormal_nociception_after | 1.98880673 |
| 16 | MP0002653_abnormal_ependyma_morphology | 1.96358660 |
| 17 | MP0005174_abnormal_tail_pigmentation | 1.92334680 |
| 18 | MP0003880_abnormal_central_pattern | 1.91701493 |
| 19 | MP0003718_maternal_effect | 1.90314824 |
| 20 | MP0002095_abnormal_skin_pigmentation | 1.89470704 |
| 21 | MP0002163_abnormal_gland_morphology | 1.89264437 |
| 22 | MP0006036_abnormal_mitochondrial_physio | 1.85045767 |
| 23 | MP0005083_abnormal_biliary_tract | 1.81883504 |
| 24 | MP0002160_abnormal_reproductive_system | 1.81855155 |
| 25 | MP0003111_abnormal_nucleus_morphology | 1.79824680 |
| 26 | MP0000015_abnormal_ear_pigmentation | 1.77134420 |
| 27 | MP0005551_abnormal_eye_electrophysiolog | 1.74860473 |
| 28 | MP0001919_abnormal_reproductive_system | 1.74497667 |
| 29 | MP0008877_abnormal_DNA_methylation | 1.73962329 |
| 30 | MP0006035_abnormal_mitochondrial_morpho | 1.72705089 |
| 31 | MP0003252_abnormal_bile_duct | 1.70643282 |
| 32 | MP0005389_reproductive_system_phenotype | 1.66275890 |
| 33 | MP0003646_muscle_fatigue | 1.63015905 |
| 34 | MP0003950_abnormal_plasma_membrane | 1.60873613 |
| 35 | MP0005394_taste/olfaction_phenotype | 1.55750733 |
| 36 | MP0005499_abnormal_olfactory_system | 1.55750733 |
| 37 | MP0008932_abnormal_embryonic_tissue | 1.50483486 |
| 38 | MP0000372_irregular_coat_pigmentation | 1.49748664 |
| 39 | MP0000569_abnormal_digit_pigmentation | 1.42097265 |
| 40 | MP0001324_abnormal_eye_pigmentation | 1.39635979 |
| 41 | MP0003077_abnormal_cell_cycle | 1.37706386 |
| 42 | MP0001485_abnormal_pinna_reflex | 1.30520326 |
| 43 | MP0000749_muscle_degeneration | 1.29925943 |
| 44 | MP0004145_abnormal_muscle_electrophysio | 1.28225164 |
| 45 | MP0002234_abnormal_pharynx_morphology | 1.23657413 |
| 46 | MP0002210_abnormal_sex_determination | 1.23620878 |
| 47 | MP0001968_abnormal_touch/_nociception | 1.21588421 |
| 48 | MP0003195_calcinosis | 1.21118032 |
| 49 | MP0010030_abnormal_orbit_morphology | 1.18564383 |
| 50 | MP0002938_white_spotting | 1.16540205 |
| 51 | MP0000566_synostosis | 1.16250837 |
| 52 | MP0001529_abnormal_vocalization | 1.16235945 |
| 53 | MP0001188_hyperpigmentation | 1.13395509 |
| 54 | MP0001929_abnormal_gametogenesis | 1.10772217 |
| 55 | MP0000751_myopathy | 1.09781796 |
| 56 | MP0006072_abnormal_retinal_apoptosis | 1.09524187 |
| 57 | MP0005360_urolithiasis | 1.08890023 |
| 58 | MP0001177_atelectasis | 1.07012164 |
| 59 | MP0000747_muscle_weakness | 0.98029376 |
| 60 | MP0004885_abnormal_endolymph | 0.97906980 |
| 61 | MP0005379_endocrine/exocrine_gland_phen | 0.97704144 |
| 62 | MP0005248_abnormal_Harderian_gland | 0.97618779 |
| 63 | MP0002090_abnormal_vision | 0.97205089 |
| 64 | MP0001764_abnormal_homeostasis | 0.97151410 |
| 65 | MP0005195_abnormal_posterior_eye | 0.95713269 |
| 66 | MP0001986_abnormal_taste_sensitivity | 0.94609211 |
| 67 | MP0005377_hearing/vestibular/ear_phenot | 0.93686053 |
| 68 | MP0003878_abnormal_ear_physiology | 0.93686053 |
| 69 | MP0005671_abnormal_response_to | 0.90916772 |
| 70 | MP0003186_abnormal_redox_activity | 0.90504954 |
| 71 | MP0008872_abnormal_physiological_respon | 0.89961246 |
| 72 | MP0003567_abnormal_fetal_cardiomyocyte | 0.87443868 |
| 73 | MP0003136_yellow_coat_color | 0.87285980 |
| 74 | MP0005085_abnormal_gallbladder_physiolo | 0.84570805 |
| 75 | MP0002837_dystrophic_cardiac_calcinosis | 0.82183535 |
| 76 | MP0001145_abnormal_male_reproductive | 0.81139470 |
| 77 | MP0000653_abnormal_sex_gland | 0.80923019 |
| 78 | MP0009745_abnormal_behavioral_response | 0.79805592 |
| 79 | MP0001119_abnormal_female_reproductive | 0.79442149 |
| 80 | MP0000427_abnormal_hair_cycle | 0.78793121 |
| 81 | MP0009053_abnormal_anal_canal | 0.77038979 |
| 82 | MP0003011_delayed_dark_adaptation | 0.77010810 |
| 83 | MP0002272_abnormal_nervous_system | 0.76447365 |
| 84 | MP0008875_abnormal_xenobiotic_pharmacok | 0.76373727 |
| 85 | MP0005266_abnormal_metabolism | 0.75244269 |
| 86 | MP0001486_abnormal_startle_reflex | 0.75151052 |
| 87 | MP0004147_increased_porphyrin_level | 0.74953245 |
| 88 | MP0003941_abnormal_skin_development | 0.73198592 |
| 89 | MP0000049_abnormal_middle_ear | 0.72771248 |
| 90 | MP0003698_abnormal_male_reproductive | 0.72722623 |
| 91 | MP0005197_abnormal_uvea_morphology | 0.71777380 |
| 92 | MP0002277_abnormal_respiratory_mucosa | 0.71650737 |
| 93 | MP0001501_abnormal_sleep_pattern | 0.70515848 |
| 94 | MP0005084_abnormal_gallbladder_morpholo | 0.66626133 |
| 95 | MP0002233_abnormal_nose_morphology | 0.65873267 |
| 96 | MP0000631_abnormal_neuroendocrine_gland | 0.65711223 |
| 97 | MP0005391_vision/eye_phenotype | 0.65440234 |
| 98 | MP0005636_abnormal_mineral_homeostasis | 0.64866607 |
| 99 | MP0002184_abnormal_innervation | 0.62939618 |
| 100 | MP0009046_muscle_twitch | 0.62804490 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | B lymphocytopenia (HP:0010976) | 5.35876243 |
| 2 | Reticulocytopenia (HP:0001896) | 4.99140965 |
| 3 | Abnormality of B cell number (HP:0010975) | 4.80673304 |
| 4 | Abnormality of alanine metabolism (HP:0010916) | 3.85021848 |
| 5 | Hyperalaninemia (HP:0003348) | 3.85021848 |
| 6 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.85021848 |
| 7 | Acute encephalopathy (HP:0006846) | 3.78430244 |
| 8 | IgM deficiency (HP:0002850) | 3.73762393 |
| 9 | Acute necrotizing encephalopathy (HP:0006965) | 3.68831260 |
| 10 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.66269114 |
| 11 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 3.49209901 |
| 12 | Mitochondrial inheritance (HP:0001427) | 3.06880321 |
| 13 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 3.06129476 |
| 14 | Increased IgM level (HP:0003496) | 3.02165474 |
| 15 | Absent thumb (HP:0009777) | 3.01079161 |
| 16 | Duplicated collecting system (HP:0000081) | 2.99152255 |
| 17 | Chromsome breakage (HP:0040012) | 2.96980387 |
| 18 | Pancytopenia (HP:0001876) | 2.87242799 |
| 19 | Increased CSF lactate (HP:0002490) | 2.85833478 |
| 20 | Progressive macrocephaly (HP:0004481) | 2.85703567 |
| 21 | Abnormality of the renal collecting system (HP:0004742) | 2.83405079 |
| 22 | Abnormality of DNA repair (HP:0003254) | 2.81199197 |
| 23 | Delayed epiphyseal ossification (HP:0002663) | 2.79310925 |
| 24 | Birth length less than 3rd percentile (HP:0003561) | 2.77129222 |
| 25 | Abnormality of the labia minora (HP:0012880) | 2.75743662 |
| 26 | IgG deficiency (HP:0004315) | 2.65778248 |
| 27 | Hyperglycinuria (HP:0003108) | 2.63416695 |
| 28 | Autoimmune thrombocytopenia (HP:0001973) | 2.60018833 |
| 29 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 2.55950428 |
| 30 | Chronic bronchitis (HP:0004469) | 2.55792514 |
| 31 | Hyperglycinemia (HP:0002154) | 2.55541271 |
| 32 | Hepatic necrosis (HP:0002605) | 2.53840775 |
| 33 | Abnormality of serum amino acid levels (HP:0003112) | 2.50671027 |
| 34 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.49662869 |
| 35 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.47726476 |
| 36 | Colon cancer (HP:0003003) | 2.43209426 |
| 37 | Meckel diverticulum (HP:0002245) | 2.42643897 |
| 38 | 3-Methylglutaconic aciduria (HP:0003535) | 2.40811020 |
| 39 | Abnormal hair whorl (HP:0010721) | 2.40191170 |
| 40 | Hepatocellular necrosis (HP:0001404) | 2.38096867 |
| 41 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.36735725 |
| 42 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.29732128 |
| 43 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.29732128 |
| 44 | Retinal atrophy (HP:0001105) | 2.28430512 |
| 45 | Lactic acidosis (HP:0003128) | 2.27942279 |
| 46 | Severe combined immunodeficiency (HP:0004430) | 2.26243791 |
| 47 | Abnormality of the ileum (HP:0001549) | 2.26113245 |
| 48 | Macrocytic anemia (HP:0001972) | 2.20510643 |
| 49 | Cerebral edema (HP:0002181) | 2.20353020 |
| 50 | Radial bowing (HP:0002986) | 2.16861312 |
| 51 | Autoimmune hemolytic anemia (HP:0001890) | 2.15627784 |
| 52 | Increased serum lactate (HP:0002151) | 2.14051525 |
| 53 | Respiratory failure (HP:0002878) | 2.13108551 |
| 54 | Hypoplasia of the radius (HP:0002984) | 2.12758971 |
| 55 | Type II lissencephaly (HP:0007260) | 2.12091153 |
| 56 | Cleft eyelid (HP:0000625) | 2.10889218 |
| 57 | Progressive microcephaly (HP:0000253) | 2.10794959 |
| 58 | Fibular aplasia (HP:0002990) | 2.10290408 |
| 59 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.08512572 |
| 60 | Abnormality of the preputium (HP:0100587) | 2.03386506 |
| 61 | Increased intramyocellular lipid droplets (HP:0012240) | 2.02251255 |
| 62 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.02240036 |
| 63 | Congenital stationary night blindness (HP:0007642) | 2.02013144 |
| 64 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 2.01604499 |
| 65 | Absent epiphyses (HP:0010577) | 2.01604499 |
| 66 | Abnormality of chromosome stability (HP:0003220) | 2.00688172 |
| 67 | Absent/shortened dynein arms (HP:0200106) | 1.98707824 |
| 68 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.98707824 |
| 69 | Methylmalonic aciduria (HP:0012120) | 1.98058481 |
| 70 | Ectopic kidney (HP:0000086) | 1.96810584 |
| 71 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.93083398 |
| 72 | Septo-optic dysplasia (HP:0100842) | 1.92813585 |
| 73 | Limb hypertonia (HP:0002509) | 1.92308115 |
| 74 | Abnormal ciliary motility (HP:0012262) | 1.91730278 |
| 75 | Optic nerve hypoplasia (HP:0000609) | 1.90549897 |
| 76 | Short thumb (HP:0009778) | 1.90523012 |
| 77 | Abnormality of magnesium homeostasis (HP:0004921) | 1.89806371 |
| 78 | Clubbing of toes (HP:0100760) | 1.89385140 |
| 79 | Type 2 muscle fiber atrophy (HP:0003554) | 1.88589420 |
| 80 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.86307804 |
| 81 | Abnormality of glycine metabolism (HP:0010895) | 1.86307804 |
| 82 | Abnormality of pyrimidine metabolism (HP:0004353) | 1.86287953 |
| 83 | Duplication of thumb phalanx (HP:0009942) | 1.82452105 |
| 84 | Type I transferrin isoform profile (HP:0003642) | 1.78553467 |
| 85 | Oligodactyly (hands) (HP:0001180) | 1.77328439 |
| 86 | Optic disc pallor (HP:0000543) | 1.77321824 |
| 87 | Cellular immunodeficiency (HP:0005374) | 1.75859773 |
| 88 | Combined immunodeficiency (HP:0005387) | 1.75704990 |
| 89 | Abnormal number of erythroid precursors (HP:0012131) | 1.74748171 |
| 90 | Abnormality of the pons (HP:0007361) | 1.74722098 |
| 91 | Retinal dysplasia (HP:0007973) | 1.73584809 |
| 92 | Eosinophilia (HP:0001880) | 1.72158814 |
| 93 | Pallor (HP:0000980) | 1.72066872 |
| 94 | Hypomagnesemia (HP:0002917) | 1.71528552 |
| 95 | Gonadotropin excess (HP:0000837) | 1.71159328 |
| 96 | Aplasia involving forearm bones (HP:0009822) | 1.70790499 |
| 97 | Absent forearm bone (HP:0003953) | 1.70790499 |
| 98 | Mesangial abnormality (HP:0001966) | 1.70701776 |
| 99 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.68713273 |
| 100 | Inability to walk (HP:0002540) | 1.68647423 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ZAK | 4.17201718 |
| 2 | BUB1 | 3.90163656 |
| 3 | MST4 | 3.45612284 |
| 4 | TLK1 | 2.94399237 |
| 5 | VRK2 | 2.74051091 |
| 6 | WNK4 | 2.44729733 |
| 7 | TRIM28 | 2.44687052 |
| 8 | VRK1 | 2.30656950 |
| 9 | KDR | 2.30272616 |
| 10 | MAP3K12 | 2.24130408 |
| 11 | PLK4 | 2.19254532 |
| 12 | NEK1 | 2.08642986 |
| 13 | STK39 | 2.01076691 |
| 14 | WEE1 | 1.97402081 |
| 15 | OXSR1 | 1.92549581 |
| 16 | MAPKAPK3 | 1.92436691 |
| 17 | CDC7 | 1.88085609 |
| 18 | OBSCN | 1.81560242 |
| 19 | NUAK1 | 1.74779931 |
| 20 | BMPR1B | 1.74779282 |
| 21 | CDK19 | 1.73122399 |
| 22 | CSNK1G1 | 1.69589452 |
| 23 | BCR | 1.57157064 |
| 24 | CSNK1G3 | 1.48367052 |
| 25 | TXK | 1.35253311 |
| 26 | ADRBK2 | 1.34426122 |
| 27 | CSNK1A1L | 1.28883150 |
| 28 | CSNK1G2 | 1.27579090 |
| 29 | MAP3K9 | 1.24808723 |
| 30 | TAF1 | 1.19725282 |
| 31 | PLK3 | 1.14112831 |
| 32 | CDK15 | 1.12688418 |
| 33 | CDK18 | 1.11751742 |
| 34 | ATR | 1.10035902 |
| 35 | GRK1 | 1.09838330 |
| 36 | KSR1 | 1.09350640 |
| 37 | PDK2 | 1.06345185 |
| 38 | TESK2 | 1.04309270 |
| 39 | PBK | 1.01775711 |
| 40 | CDK11A | 1.00010295 |
| 41 | PLK1 | 0.99298544 |
| 42 | PRKCI | 0.99002719 |
| 43 | STK16 | 0.98519188 |
| 44 | PINK1 | 0.97743029 |
| 45 | WNK1 | 0.96465143 |
| 46 | ABL2 | 0.95244105 |
| 47 | CDK14 | 0.94355540 |
| 48 | AURKB | 0.94059533 |
| 49 | WNK3 | 0.84679204 |
| 50 | CHEK2 | 0.82757936 |
| 51 | DYRK2 | 0.81571082 |
| 52 | ITK | 0.81179677 |
| 53 | ARAF | 0.80254813 |
| 54 | AURKA | 0.79560917 |
| 55 | PAK6 | 0.78933171 |
| 56 | NME1 | 0.78904337 |
| 57 | TTK | 0.78602650 |
| 58 | LIMK1 | 0.76926236 |
| 59 | KSR2 | 0.74775037 |
| 60 | DAPK1 | 0.73561452 |
| 61 | IKBKE | 0.73059930 |
| 62 | PNCK | 0.72767781 |
| 63 | TEC | 0.72220984 |
| 64 | TIE1 | 0.71269534 |
| 65 | ADRBK1 | 0.70822370 |
| 66 | TSSK6 | 0.69291407 |
| 67 | MAPK13 | 0.67881140 |
| 68 | NLK | 0.66548433 |
| 69 | PIM1 | 0.65874807 |
| 70 | BCKDK | 0.64491489 |
| 71 | MAP3K11 | 0.63971035 |
| 72 | MKNK2 | 0.62845799 |
| 73 | ACVR1B | 0.62450422 |
| 74 | PRKCG | 0.61926971 |
| 75 | PTK2B | 0.57981290 |
| 76 | PHKG2 | 0.54799388 |
| 77 | PHKG1 | 0.54799388 |
| 78 | CAMK1 | 0.51938923 |
| 79 | STK11 | 0.51868157 |
| 80 | CSNK1A1 | 0.51072568 |
| 81 | MOS | 0.50622603 |
| 82 | CSNK2A1 | 0.50055090 |
| 83 | PLK2 | 0.49459003 |
| 84 | MAPK11 | 0.49187022 |
| 85 | BRSK1 | 0.48073877 |
| 86 | PAK3 | 0.47744728 |
| 87 | CSNK2A2 | 0.47329469 |
| 88 | MUSK | 0.44715908 |
| 89 | FRK | 0.42860680 |
| 90 | DYRK1A | 0.42847061 |
| 91 | PAK1 | 0.42127879 |
| 92 | INSRR | 0.41177256 |
| 93 | RAF1 | 0.40748072 |
| 94 | CHEK1 | 0.38576741 |
| 95 | MARK3 | 0.37172852 |
| 96 | PRKCE | 0.33416404 |
| 97 | CSNK1E | 0.33297466 |
| 98 | MAPKAPK5 | 0.32858574 |
| 99 | RPS6KA5 | 0.32497319 |
| 100 | CDK4 | 0.32051966 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.95140506 |
| 2 | DNA replication_Homo sapiens_hsa03030 | 3.73177503 |
| 3 | Proteasome_Homo sapiens_hsa03050 | 3.55336685 |
| 4 | Ribosome_Homo sapiens_hsa03010 | 3.51040696 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 3.26585221 |
| 6 | Mismatch repair_Homo sapiens_hsa03430 | 2.94848862 |
| 7 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.60986100 |
| 8 | Huntingtons disease_Homo sapiens_hsa05016 | 2.52935876 |
| 9 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.44622464 |
| 10 | Alzheimers disease_Homo sapiens_hsa05010 | 2.28550194 |
| 11 | Homologous recombination_Homo sapiens_hsa03440 | 2.27506687 |
| 12 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.24721851 |
| 13 | Base excision repair_Homo sapiens_hsa03410 | 2.24287578 |
| 14 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.18284864 |
| 15 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 2.17552943 |
| 16 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.17020631 |
| 17 | RNA polymerase_Homo sapiens_hsa03020 | 2.09449186 |
| 18 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 2.00098823 |
| 19 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.99891043 |
| 20 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.91492098 |
| 21 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.88990106 |
| 22 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.85751035 |
| 23 | Phototransduction_Homo sapiens_hsa04744 | 1.77250724 |
| 24 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.72189539 |
| 25 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.68207675 |
| 26 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.62017220 |
| 27 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.58497076 |
| 28 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.50013909 |
| 29 | RNA degradation_Homo sapiens_hsa03018 | 1.46393254 |
| 30 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.41164375 |
| 31 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.34073768 |
| 32 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.31156857 |
| 33 | Basal transcription factors_Homo sapiens_hsa03022 | 1.27519698 |
| 34 | Protein export_Homo sapiens_hsa03060 | 1.20083935 |
| 35 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.19775644 |
| 36 | Purine metabolism_Homo sapiens_hsa00230 | 1.13132507 |
| 37 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.07706286 |
| 38 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.04782031 |
| 39 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.01151776 |
| 40 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.99143981 |
| 41 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.97624218 |
| 42 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.96137025 |
| 43 | Cell cycle_Homo sapiens_hsa04110 | 0.95332090 |
| 44 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.92828082 |
| 45 | Carbon metabolism_Homo sapiens_hsa01200 | 0.91828864 |
| 46 | Spliceosome_Homo sapiens_hsa03040 | 0.90153316 |
| 47 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.87574862 |
| 48 | RNA transport_Homo sapiens_hsa03013 | 0.87245687 |
| 49 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.86355031 |
| 50 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.86071132 |
| 51 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.76707283 |
| 52 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.76480310 |
| 53 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.73476509 |
| 54 | Metabolic pathways_Homo sapiens_hsa01100 | 0.72706663 |
| 55 | Peroxisome_Homo sapiens_hsa04146 | 0.70464138 |
| 56 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.69734479 |
| 57 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.66919989 |
| 58 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.65377756 |
| 59 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.64748602 |
| 60 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.61457658 |
| 61 | Olfactory transduction_Homo sapiens_hsa04740 | 0.60424491 |
| 62 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.58833015 |
| 63 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.57878580 |
| 64 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.54645193 |
| 65 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.53020144 |
| 66 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.52206932 |
| 67 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.51332648 |
| 68 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.50244445 |
| 69 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.50161667 |
| 70 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.50084979 |
| 71 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.40856147 |
| 72 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.39304350 |
| 73 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.38969063 |
| 74 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.37838873 |
| 75 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.34690446 |
| 76 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.32770151 |
| 77 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.32678510 |
| 78 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.30728097 |
| 79 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.30581081 |
| 80 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.30576221 |
| 81 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.29038577 |
| 82 | Retinol metabolism_Homo sapiens_hsa00830 | 0.26800334 |
| 83 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.26686267 |
| 84 | Nicotine addiction_Homo sapiens_hsa05033 | 0.23260348 |
| 85 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.21890623 |
| 86 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.21257694 |
| 87 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.20241123 |
| 88 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.19177036 |
| 89 | Histidine metabolism_Homo sapiens_hsa00340 | 0.17039906 |
| 90 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.15742915 |
| 91 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.14284762 |
| 92 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.13380547 |
| 93 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.12758928 |
| 94 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.12593786 |
| 95 | Mineral absorption_Homo sapiens_hsa04978 | 0.12089161 |
| 96 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.11941790 |
| 97 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.11486752 |
| 98 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.11359467 |
| 99 | Morphine addiction_Homo sapiens_hsa05032 | 0.09525038 |
| 100 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.09248063 |

