

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | sequestering of actin monomers (GO:0042989) | 6.23324991 |
| 2 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.48384030 |
| 3 | viral transcription (GO:0019083) | 5.41130855 |
| 4 | translational termination (GO:0006415) | 5.23826280 |
| 5 | mitochondrial fragmentation involved in apoptotic process (GO:0043653) | 5.22886153 |
| 6 | ribosomal small subunit assembly (GO:0000028) | 5.20959791 |
| 7 | ATP synthesis coupled proton transport (GO:0015986) | 5.01898383 |
| 8 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.01898383 |
| 9 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.84661423 |
| 10 | negative regulation of activin receptor signaling pathway (GO:0032926) | 4.83480025 |
| 11 | cotranslational protein targeting to membrane (GO:0006613) | 4.82326962 |
| 12 | protein targeting to ER (GO:0045047) | 4.77336374 |
| 13 | regulation of mesoderm development (GO:2000380) | 4.66515299 |
| 14 | maturation of SSU-rRNA (GO:0030490) | 4.60561004 |
| 15 | translational elongation (GO:0006414) | 4.58547669 |
| 16 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.57333620 |
| 17 | viral life cycle (GO:0019058) | 4.54438462 |
| 18 | regulation of activin receptor signaling pathway (GO:0032925) | 4.40929791 |
| 19 | protein localization to endoplasmic reticulum (GO:0070972) | 4.40915689 |
| 20 | anterograde synaptic vesicle transport (GO:0048490) | 4.21630564 |
| 21 | cellular protein complex disassembly (GO:0043624) | 4.09643461 |
| 22 | sequestering of extracellular ligand from receptor (GO:0035581) | 3.96377873 |
| 23 | photoreceptor cell maintenance (GO:0045494) | 3.96014485 |
| 24 | cell migration involved in gastrulation (GO:0042074) | 3.91297439 |
| 25 | nodal signaling pathway (GO:0038092) | 3.90728503 |
| 26 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.88092206 |
| 27 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.87253239 |
| 28 | respiratory electron transport chain (GO:0022904) | 3.85370243 |
| 29 | electron transport chain (GO:0022900) | 3.80620969 |
| 30 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.79883350 |
| 31 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.78507943 |
| 32 | regulation of development, heterochronic (GO:0040034) | 3.74724302 |
| 33 | postsynaptic membrane organization (GO:0001941) | 3.71437999 |
| 34 | platelet dense granule organization (GO:0060155) | 3.65860946 |
| 35 | regulation of timing of cell differentiation (GO:0048505) | 3.59042912 |
| 36 | anterograde axon cargo transport (GO:0008089) | 3.56718627 |
| 37 | translational initiation (GO:0006413) | 3.54970301 |
| 38 | head development (GO:0060322) | 3.50231289 |
| 39 | histone exchange (GO:0043486) | 3.47241349 |
| 40 | behavioral response to nicotine (GO:0035095) | 3.46736867 |
| 41 | centriole replication (GO:0007099) | 3.45543320 |
| 42 | signal transduction involved in regulation of gene expression (GO:0023019) | 3.45513125 |
| 43 | mannosylation (GO:0097502) | 3.45159947 |
| 44 | termination of RNA polymerase III transcription (GO:0006386) | 3.41965123 |
| 45 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.41965123 |
| 46 | primitive streak formation (GO:0090009) | 3.40257055 |
| 47 | detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580) | 3.35740474 |
| 48 | protein complex disassembly (GO:0043241) | 3.35406126 |
| 49 | L-serine metabolic process (GO:0006563) | 3.34734302 |
| 50 | melanosome organization (GO:0032438) | 3.31889661 |
| 51 | ribosomal small subunit biogenesis (GO:0042274) | 3.29319704 |
| 52 | epithelial cilium movement (GO:0003351) | 3.25791716 |
| 53 | protein neddylation (GO:0045116) | 3.20611037 |
| 54 | protein heterotetramerization (GO:0051290) | 3.19343108 |
| 55 | macromolecular complex disassembly (GO:0032984) | 3.18529181 |
| 56 | positive regulation of gastrulation (GO:2000543) | 3.18492028 |
| 57 | protein targeting to membrane (GO:0006612) | 3.17630308 |
| 58 | pigment granule organization (GO:0048753) | 3.17282812 |
| 59 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.14796971 |
| 60 | cullin deneddylation (GO:0010388) | 3.13742844 |
| 61 | L-ascorbic acid metabolic process (GO:0019852) | 3.06261067 |
| 62 | serotonin receptor signaling pathway (GO:0007210) | 3.04621857 |
| 63 | phosphorelay signal transduction system (GO:0000160) | 3.03523549 |
| 64 | mitochondrial fission (GO:0000266) | 3.02019378 |
| 65 | translation (GO:0006412) | 2.98563132 |
| 66 | positive regulation of mitochondrial fission (GO:0090141) | 2.95841232 |
| 67 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.95031250 |
| 68 | organelle disassembly (GO:1903008) | 2.92324685 |
| 69 | oxidative phosphorylation (GO:0006119) | 2.89936147 |
| 70 | mRNA catabolic process (GO:0006402) | 2.89267471 |
| 71 | rRNA modification (GO:0000154) | 2.89062835 |
| 72 | ATP biosynthetic process (GO:0006754) | 2.84821996 |
| 73 | inner ear receptor cell differentiation (GO:0060113) | 2.84241151 |
| 74 | spliceosomal complex assembly (GO:0000245) | 2.83634242 |
| 75 | regulation of transmission of nerve impulse (GO:0051969) | 2.82940132 |
| 76 | DNA integration (GO:0015074) | 2.82681570 |
| 77 | deoxyribose phosphate catabolic process (GO:0046386) | 2.82032028 |
| 78 | deoxyribonucleotide catabolic process (GO:0009264) | 2.80973611 |
| 79 | CENP-A containing nucleosome assembly (GO:0034080) | 2.80190028 |
| 80 | regulation of cilium movement (GO:0003352) | 2.79746304 |
| 81 | spermatid nucleus differentiation (GO:0007289) | 2.77234827 |
| 82 | activin receptor signaling pathway (GO:0032924) | 2.76094059 |
| 83 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.73331370 |
| 84 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.72133419 |
| 85 | negative regulation of G2/M transition of mitotic cell cycle (GO:0010972) | 2.71592883 |
| 86 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 2.71439282 |
| 87 | nucleotide transmembrane transport (GO:1901679) | 2.69579452 |
| 88 | microtubule depolymerization (GO:0007019) | 2.68171639 |
| 89 | detection of chemical stimulus involved in sensory perception of taste (GO:0050912) | 2.68116816 |
| 90 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.67670192 |
| 91 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.67670192 |
| 92 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.67670192 |
| 93 | DNA deamination (GO:0045006) | 2.67524547 |
| 94 | chromatin remodeling at centromere (GO:0031055) | 2.66559387 |
| 95 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 2.66423380 |
| 96 | pyrimidine nucleobase catabolic process (GO:0006208) | 2.65823955 |
| 97 | aldehyde catabolic process (GO:0046185) | 2.65177111 |
| 98 | regulation of DNA endoreduplication (GO:0032875) | 2.64277797 |
| 99 | hydrogen ion transmembrane transport (GO:1902600) | 2.63947585 |
| 100 | axonemal dynein complex assembly (GO:0070286) | 2.62316042 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.39439944 |
| 2 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 4.11478001 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.90315016 |
| 4 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.63993085 |
| 5 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.50605821 |
| 6 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.43866547 |
| 7 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.07053127 |
| 8 | FUS_26573619_Chip-Seq_HEK293_Human | 2.79241397 |
| 9 | VDR_22108803_ChIP-Seq_LS180_Human | 2.70596281 |
| 10 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.58635286 |
| 11 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.54165991 |
| 12 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.50323806 |
| 13 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.40191435 |
| 14 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.35019218 |
| 15 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 2.34745467 |
| 16 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.27458935 |
| 17 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.22215171 |
| 18 | P300_19829295_ChIP-Seq_ESCs_Human | 2.11272400 |
| 19 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.09973366 |
| 20 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.09069597 |
| 21 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.03951707 |
| 22 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.99032564 |
| 23 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.98898499 |
| 24 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.93720141 |
| 25 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.85045667 |
| 26 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.81287727 |
| 27 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.80679112 |
| 28 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.72318870 |
| 29 | EWS_26573619_Chip-Seq_HEK293_Human | 1.71733089 |
| 30 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.69421863 |
| 31 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.62033526 |
| 32 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.55509334 |
| 33 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.55509334 |
| 34 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.55509334 |
| 35 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.50137484 |
| 36 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.47122436 |
| 37 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.43101482 |
| 38 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.42161497 |
| 39 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.41693693 |
| 40 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.40638302 |
| 41 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.39095554 |
| 42 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.39095554 |
| 43 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.37737165 |
| 44 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.35601254 |
| 45 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.33729705 |
| 46 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.33606196 |
| 47 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.33501961 |
| 48 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.32836465 |
| 49 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.32471984 |
| 50 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.31675326 |
| 51 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.31528207 |
| 52 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.30834058 |
| 53 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.28058356 |
| 54 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.27426168 |
| 55 | AR_20517297_ChIP-Seq_VCAP_Human | 1.26534552 |
| 56 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.25187128 |
| 57 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.23760609 |
| 58 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.23169962 |
| 59 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.23148243 |
| 60 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.22399497 |
| 61 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.21663219 |
| 62 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.21224578 |
| 63 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.20549345 |
| 64 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.19950309 |
| 65 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.16238040 |
| 66 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.14974545 |
| 67 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.14974545 |
| 68 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.14278618 |
| 69 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.13649039 |
| 70 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.11224304 |
| 71 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.11031592 |
| 72 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.10480684 |
| 73 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.09752410 |
| 74 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.09683452 |
| 75 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 1.09611461 |
| 76 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.09353869 |
| 77 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.09353869 |
| 78 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.08515594 |
| 79 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.07679183 |
| 80 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.07381292 |
| 81 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.06239446 |
| 82 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.04025647 |
| 83 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.03797597 |
| 84 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.03584503 |
| 85 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.02243024 |
| 86 | ELF5_23300383_ChIP-Seq_T47D_Human | 1.01678800 |
| 87 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.99732187 |
| 88 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.99479783 |
| 89 | AR_25329375_ChIP-Seq_VCAP_Human | 0.99479609 |
| 90 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.98980008 |
| 91 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.97009814 |
| 92 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.94433117 |
| 93 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 0.94160738 |
| 94 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 0.93526955 |
| 95 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.93476679 |
| 96 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.93186582 |
| 97 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.93010403 |
| 98 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.91627087 |
| 99 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.90557349 |
| 100 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.90078576 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000569_abnormal_digit_pigmentation | 4.63448758 |
| 2 | MP0003890_abnormal_embryonic-extraembry | 4.41745765 |
| 3 | MP0009379_abnormal_foot_pigmentation | 4.15274254 |
| 4 | MP0003283_abnormal_digestive_organ | 4.10539476 |
| 5 | MP0010030_abnormal_orbit_morphology | 3.57673366 |
| 6 | MP0004133_heterotaxia | 3.45962167 |
| 7 | MP0006292_abnormal_olfactory_placode | 3.32496346 |
| 8 | MP0000372_irregular_coat_pigmentation | 3.24934133 |
| 9 | MP0003136_yellow_coat_color | 3.14706180 |
| 10 | MP0000566_synostosis | 2.70207092 |
| 11 | MP0001529_abnormal_vocalization | 2.63285740 |
| 12 | MP0002102_abnormal_ear_morphology | 2.61316185 |
| 13 | MP0002938_white_spotting | 2.53639051 |
| 14 | MP0001485_abnormal_pinna_reflex | 2.40903323 |
| 15 | MP0004742_abnormal_vestibular_system | 2.36522681 |
| 16 | MP0005645_abnormal_hypothalamus_physiol | 2.34143081 |
| 17 | MP0002234_abnormal_pharynx_morphology | 2.22043367 |
| 18 | MP0001293_anophthalmia | 2.10947761 |
| 19 | MP0006072_abnormal_retinal_apoptosis | 2.07913921 |
| 20 | MP0003119_abnormal_digestive_system | 1.80640290 |
| 21 | MP0005075_abnormal_melanosome_morpholog | 1.72701762 |
| 22 | MP0005174_abnormal_tail_pigmentation | 1.66147418 |
| 23 | MP0000015_abnormal_ear_pigmentation | 1.66141868 |
| 24 | MP0005394_taste/olfaction_phenotype | 1.57660716 |
| 25 | MP0005499_abnormal_olfactory_system | 1.57660716 |
| 26 | MP0006276_abnormal_autonomic_nervous | 1.56778797 |
| 27 | MP0003880_abnormal_central_pattern | 1.55753557 |
| 28 | MP0004264_abnormal_extraembryonic_tissu | 1.53134002 |
| 29 | MP0003878_abnormal_ear_physiology | 1.50926313 |
| 30 | MP0005377_hearing/vestibular/ear_phenot | 1.50926313 |
| 31 | MP0001286_abnormal_eye_development | 1.40867497 |
| 32 | MP0002638_abnormal_pupillary_reflex | 1.32470754 |
| 33 | MP0002277_abnormal_respiratory_mucosa | 1.28732403 |
| 34 | MP0002095_abnormal_skin_pigmentation | 1.27275754 |
| 35 | MP0008058_abnormal_DNA_repair | 1.26710113 |
| 36 | MP0000516_abnormal_urinary_system | 1.22075412 |
| 37 | MP0005367_renal/urinary_system_phenotyp | 1.22075412 |
| 38 | MP0003787_abnormal_imprinting | 1.21948204 |
| 39 | MP0003122_maternal_imprinting | 1.21261392 |
| 40 | MP0000026_abnormal_inner_ear | 1.20011652 |
| 41 | MP0005084_abnormal_gallbladder_morpholo | 1.19591283 |
| 42 | MP0005671_abnormal_response_to | 1.19219798 |
| 43 | MP0000631_abnormal_neuroendocrine_gland | 1.18207996 |
| 44 | MP0008789_abnormal_olfactory_epithelium | 1.17857237 |
| 45 | MP0001188_hyperpigmentation | 1.14653112 |
| 46 | MP0002736_abnormal_nociception_after | 1.14520540 |
| 47 | MP0005083_abnormal_biliary_tract | 1.14188856 |
| 48 | MP0003938_abnormal_ear_development | 1.13116934 |
| 49 | MP0002282_abnormal_trachea_morphology | 1.12842658 |
| 50 | MP0005423_abnormal_somatic_nervous | 1.10443079 |
| 51 | MP0002138_abnormal_hepatobiliary_system | 1.09107242 |
| 52 | MP0004142_abnormal_muscle_tone | 1.07501299 |
| 53 | MP0008877_abnormal_DNA_methylation | 1.02591135 |
| 54 | MP0002396_abnormal_hematopoietic_system | 1.00467207 |
| 55 | MP0004145_abnormal_muscle_electrophysio | 0.99414421 |
| 56 | MP0005646_abnormal_pituitary_gland | 0.98947522 |
| 57 | MP0005085_abnormal_gallbladder_physiolo | 0.98237454 |
| 58 | MP0002233_abnormal_nose_morphology | 0.97087423 |
| 59 | MP0003137_abnormal_impulse_conducting | 0.96395034 |
| 60 | MP0001968_abnormal_touch/_nociception | 0.94742645 |
| 61 | MP0008961_abnormal_basal_metabolism | 0.92607231 |
| 62 | MP0001963_abnormal_hearing_physiology | 0.88385373 |
| 63 | MP0008872_abnormal_physiological_respon | 0.87345822 |
| 64 | MP0009046_muscle_twitch | 0.87095582 |
| 65 | MP0001881_abnormal_mammary_gland | 0.85024155 |
| 66 | MP0001764_abnormal_homeostasis | 0.84241522 |
| 67 | MP0003121_genomic_imprinting | 0.82893280 |
| 68 | MP0005408_hypopigmentation | 0.81236782 |
| 69 | MP0003252_abnormal_bile_duct | 0.78539801 |
| 70 | MP0001486_abnormal_startle_reflex | 0.78183690 |
| 71 | MP0001346_abnormal_lacrimal_gland | 0.77749608 |
| 72 | MP0002177_abnormal_outer_ear | 0.77234025 |
| 73 | MP0005253_abnormal_eye_physiology | 0.76132152 |
| 74 | MP0005195_abnormal_posterior_eye | 0.75393647 |
| 75 | MP0003635_abnormal_synaptic_transmissio | 0.74727589 |
| 76 | MP0002837_dystrophic_cardiac_calcinosis | 0.73626025 |
| 77 | MP0001986_abnormal_taste_sensitivity | 0.73260998 |
| 78 | MP0002272_abnormal_nervous_system | 0.72481883 |
| 79 | MP0008004_abnormal_stomach_pH | 0.71576238 |
| 80 | MP0001324_abnormal_eye_pigmentation | 0.69666385 |
| 81 | MP0005551_abnormal_eye_electrophysiolog | 0.69009673 |
| 82 | MP0005391_vision/eye_phenotype | 0.68359591 |
| 83 | MP0002752_abnormal_somatic_nervous | 0.65499146 |
| 84 | MP0002075_abnormal_coat/hair_pigmentati | 0.65270611 |
| 85 | MP0000428_abnormal_craniofacial_morphol | 0.63555245 |
| 86 | MP0003937_abnormal_limbs/digits/tail_de | 0.63239715 |
| 87 | MP0008995_early_reproductive_senescence | 0.62794800 |
| 88 | MP0000462_abnormal_digestive_system | 0.62223368 |
| 89 | MP0000049_abnormal_middle_ear | 0.61721515 |
| 90 | MP0005197_abnormal_uvea_morphology | 0.60980591 |
| 91 | MP0009745_abnormal_behavioral_response | 0.59077190 |
| 92 | MP0001186_pigmentation_phenotype | 0.55977749 |
| 93 | MP0003959_abnormal_lean_body | 0.54306577 |
| 94 | MP0002295_abnormal_pulmonary_circulatio | 0.54285158 |
| 95 | MP0004885_abnormal_endolymph | 0.54042052 |
| 96 | MP0001970_abnormal_pain_threshold | 0.53883066 |
| 97 | MP0003186_abnormal_redox_activity | 0.53670079 |
| 98 | MP0002557_abnormal_social/conspecific_i | 0.53052010 |
| 99 | MP0002909_abnormal_adrenal_gland | 0.52730481 |
| 100 | MP0001929_abnormal_gametogenesis | 0.52595108 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oligodactyly (hands) (HP:0001180) | 6.08161968 |
| 2 | Intestinal atresia (HP:0011100) | 5.73079186 |
| 3 | Nuclear cataract (HP:0100018) | 5.26587876 |
| 4 | Oligodactyly (HP:0012165) | 4.41619159 |
| 5 | Esophageal atresia (HP:0002032) | 4.39451868 |
| 6 | Congenital malformation of the right heart (HP:0011723) | 4.22578279 |
| 7 | Double outlet right ventricle (HP:0001719) | 4.22578279 |
| 8 | Aqueductal stenosis (HP:0002410) | 4.03031405 |
| 9 | Acute necrotizing encephalopathy (HP:0006965) | 3.89222882 |
| 10 | Reticulocytopenia (HP:0001896) | 3.88443183 |
| 11 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 3.83892815 |
| 12 | Chin dimple (HP:0010751) | 3.73553475 |
| 13 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.57928135 |
| 14 | Labial hypoplasia (HP:0000066) | 3.51237463 |
| 15 | Hypoplastic female external genitalia (HP:0012815) | 3.44069807 |
| 16 | Cleft eyelid (HP:0000625) | 3.37579653 |
| 17 | Gastrointestinal atresia (HP:0002589) | 3.21568762 |
| 18 | Progressive macrocephaly (HP:0004481) | 3.19815788 |
| 19 | Colon cancer (HP:0003003) | 3.16992149 |
| 20 | Hepatocellular necrosis (HP:0001404) | 3.16505121 |
| 21 | Acute encephalopathy (HP:0006846) | 3.10322623 |
| 22 | Mitochondrial inheritance (HP:0001427) | 3.06085824 |
| 23 | Bifid tongue (HP:0010297) | 3.03829506 |
| 24 | Anencephaly (HP:0002323) | 3.01690560 |
| 25 | Anophthalmia (HP:0000528) | 2.99709546 |
| 26 | Hepatic necrosis (HP:0002605) | 2.95879472 |
| 27 | Down-sloping shoulders (HP:0200021) | 2.95474824 |
| 28 | Absent radius (HP:0003974) | 2.88498786 |
| 29 | Abnormality of the pubic bones (HP:0003172) | 2.84712106 |
| 30 | Retinal dysplasia (HP:0007973) | 2.79668895 |
| 31 | Absent forearm bone (HP:0003953) | 2.79645224 |
| 32 | Aplasia involving forearm bones (HP:0009822) | 2.79645224 |
| 33 | Type II lissencephaly (HP:0007260) | 2.76650379 |
| 34 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.73862925 |
| 35 | Absent eyebrow (HP:0002223) | 2.69841713 |
| 36 | Abnormal number of erythroid precursors (HP:0012131) | 2.67815365 |
| 37 | Abdominal situs inversus (HP:0003363) | 2.67435271 |
| 38 | Abnormality of abdominal situs (HP:0011620) | 2.67435271 |
| 39 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.65174715 |
| 40 | Triphalangeal thumb (HP:0001199) | 2.63776394 |
| 41 | Cupped ear (HP:0000378) | 2.62625627 |
| 42 | Pancreatic cysts (HP:0001737) | 2.61620270 |
| 43 | Abnormality of the parathyroid morphology (HP:0011766) | 2.59395829 |
| 44 | Renal hypoplasia (HP:0000089) | 2.59158691 |
| 45 | Increased CSF lactate (HP:0002490) | 2.56359195 |
| 46 | Abnormality of the labia (HP:0000058) | 2.56088296 |
| 47 | Cellular immunodeficiency (HP:0005374) | 2.52149375 |
| 48 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.46205036 |
| 49 | Hemivertebrae (HP:0002937) | 2.45959869 |
| 50 | Carpal bone hypoplasia (HP:0001498) | 2.43411487 |
| 51 | Chromsome breakage (HP:0040012) | 2.42382333 |
| 52 | Horseshoe kidney (HP:0000085) | 2.40816649 |
| 53 | Optic disc pallor (HP:0000543) | 2.39852298 |
| 54 | Stenosis of the external auditory canal (HP:0000402) | 2.38381456 |
| 55 | Abnormality of the ileum (HP:0001549) | 2.36816482 |
| 56 | Abnormality of the labia minora (HP:0012880) | 2.31785451 |
| 57 | Hypoplasia of the ulna (HP:0003022) | 2.29705895 |
| 58 | Hypoplastic labia majora (HP:0000059) | 2.28119927 |
| 59 | Cerebral edema (HP:0002181) | 2.27518836 |
| 60 | Macrocytic anemia (HP:0001972) | 2.25962943 |
| 61 | Meckel diverticulum (HP:0002245) | 2.22718112 |
| 62 | Cutaneous finger syndactyly (HP:0010554) | 2.20910983 |
| 63 | Zonular cataract (HP:0010920) | 2.18006875 |
| 64 | Mixed hearing impairment (HP:0000410) | 2.17781970 |
| 65 | Anal stenosis (HP:0002025) | 2.11320401 |
| 66 | Short thumb (HP:0009778) | 2.10604905 |
| 67 | Aplasia/Hypoplasia of the ulna (HP:0006495) | 2.08268872 |
| 68 | Septo-optic dysplasia (HP:0100842) | 2.07962106 |
| 69 | Chronic sinusitis (HP:0011109) | 2.05591435 |
| 70 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.05465913 |
| 71 | Congenital, generalized hypertrichosis (HP:0004540) | 2.05066695 |
| 72 | Abnormality of the labia majora (HP:0012881) | 2.03673011 |
| 73 | Bilateral microphthalmos (HP:0007633) | 1.99256833 |
| 74 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.98700341 |
| 75 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.98700341 |
| 76 | Leukodystrophy (HP:0002415) | 1.97615643 |
| 77 | Abnormality of the duodenum (HP:0002246) | 1.96841958 |
| 78 | Optic nerve hypoplasia (HP:0000609) | 1.95938553 |
| 79 | Growth hormone deficiency (HP:0000824) | 1.94482111 |
| 80 | Attenuation of retinal blood vessels (HP:0007843) | 1.93226929 |
| 81 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.90278002 |
| 82 | Pancreatic fibrosis (HP:0100732) | 1.88178764 |
| 83 | Maternal diabetes (HP:0009800) | 1.86726340 |
| 84 | Deep palmar crease (HP:0006191) | 1.85175839 |
| 85 | Volvulus (HP:0002580) | 1.83630337 |
| 86 | Absent hair (HP:0002298) | 1.82974100 |
| 87 | Albinism (HP:0001022) | 1.80913313 |
| 88 | Cutaneous syndactyly (HP:0012725) | 1.80757334 |
| 89 | Renal agenesis (HP:0000104) | 1.80201291 |
| 90 | Anterior segment dysgenesis (HP:0007700) | 1.79708949 |
| 91 | 3-Methylglutaconic aciduria (HP:0003535) | 1.79309228 |
| 92 | Abnormality of midbrain morphology (HP:0002418) | 1.78353327 |
| 93 | Molar tooth sign on MRI (HP:0002419) | 1.78353327 |
| 94 | Abnormality of the pons (HP:0007361) | 1.77678686 |
| 95 | True hermaphroditism (HP:0010459) | 1.75131502 |
| 96 | Concave nail (HP:0001598) | 1.72258204 |
| 97 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.71525864 |
| 98 | Hypoplasia of the pons (HP:0012110) | 1.68547951 |
| 99 | Aplasia/hypoplasia of the humerus (HP:0006507) | 1.66348371 |
| 100 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.65910963 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SIK2 | 5.26325862 |
| 2 | CDK19 | 4.35269542 |
| 3 | VRK2 | 4.01833567 |
| 4 | ERBB4 | 3.73854174 |
| 5 | WNK3 | 3.67889855 |
| 6 | NEK2 | 3.03679348 |
| 7 | FLT3 | 2.81793658 |
| 8 | BRD4 | 2.81199927 |
| 9 | BMPR1B | 2.65808209 |
| 10 | TLK1 | 2.60727531 |
| 11 | ZAK | 2.57892853 |
| 12 | MAP4K2 | 2.51776440 |
| 13 | VRK1 | 2.46576682 |
| 14 | STK16 | 2.30349904 |
| 15 | FRK | 1.82628387 |
| 16 | PASK | 1.72570413 |
| 17 | GRK1 | 1.59336037 |
| 18 | BRSK2 | 1.55038413 |
| 19 | OXSR1 | 1.52008773 |
| 20 | TNIK | 1.49843291 |
| 21 | PRKD3 | 1.45827235 |
| 22 | NUAK1 | 1.44930161 |
| 23 | TGFBR1 | 1.43496911 |
| 24 | ACVR1B | 1.41233632 |
| 25 | MARK3 | 1.38982203 |
| 26 | PLK2 | 1.37761122 |
| 27 | PINK1 | 1.26476764 |
| 28 | KIT | 1.19307651 |
| 29 | BMPR2 | 1.19153099 |
| 30 | MAP3K6 | 1.11848324 |
| 31 | DYRK2 | 1.09176128 |
| 32 | DAPK3 | 1.08515795 |
| 33 | BCKDK | 1.08372858 |
| 34 | GRK7 | 1.03692226 |
| 35 | MAP3K9 | 1.02146379 |
| 36 | PIK3CG | 0.99493908 |
| 37 | STK4 | 0.98616741 |
| 38 | NEK1 | 0.96984295 |
| 39 | MAP3K12 | 0.96300297 |
| 40 | CHEK2 | 0.94830247 |
| 41 | CASK | 0.92056430 |
| 42 | BUB1 | 0.81967626 |
| 43 | PLK3 | 0.81881308 |
| 44 | CDC7 | 0.80987396 |
| 45 | TAF1 | 0.79405159 |
| 46 | MAP4K1 | 0.75264715 |
| 47 | ADRBK2 | 0.75175434 |
| 48 | PRKCE | 0.73388650 |
| 49 | OBSCN | 0.69863224 |
| 50 | BRSK1 | 0.65201672 |
| 51 | DAPK1 | 0.63297605 |
| 52 | MAPK13 | 0.61427175 |
| 53 | PKN1 | 0.61144824 |
| 54 | ABL2 | 0.58183761 |
| 55 | SIK3 | 0.56723076 |
| 56 | ADRBK1 | 0.56214986 |
| 57 | CHUK | 0.55274216 |
| 58 | MAP2K7 | 0.54056468 |
| 59 | MATK | 0.53377261 |
| 60 | RPS6KA5 | 0.53038088 |
| 61 | SRPK1 | 0.52431748 |
| 62 | NME1 | 0.49887149 |
| 63 | AURKB | 0.47773567 |
| 64 | ERBB3 | 0.42399177 |
| 65 | RPS6KA4 | 0.42109114 |
| 66 | PHKG2 | 0.40874465 |
| 67 | PHKG1 | 0.40874465 |
| 68 | CDK7 | 0.40189253 |
| 69 | PKN2 | 0.39913906 |
| 70 | PRKCI | 0.39629262 |
| 71 | NTRK3 | 0.38554512 |
| 72 | MAP3K13 | 0.37897751 |
| 73 | INSRR | 0.35892268 |
| 74 | MARK1 | 0.35340104 |
| 75 | PRKCG | 0.35012461 |
| 76 | CSNK1A1 | 0.34378602 |
| 77 | CSF1R | 0.32188099 |
| 78 | MST4 | 0.31843042 |
| 79 | MAP2K6 | 0.30888101 |
| 80 | TXK | 0.30438470 |
| 81 | BCR | 0.30374756 |
| 82 | PLK1 | 0.28576065 |
| 83 | MYLK | 0.28062796 |
| 84 | IKBKB | 0.27508203 |
| 85 | FGFR2 | 0.26999380 |
| 86 | LYN | 0.25783242 |
| 87 | PRKG1 | 0.25505621 |
| 88 | MINK1 | 0.23789680 |
| 89 | TAOK3 | 0.23551888 |
| 90 | CSNK2A1 | 0.23323723 |
| 91 | AURKA | 0.22457954 |
| 92 | WNK4 | 0.21938456 |
| 93 | SYK | 0.21046899 |
| 94 | CSNK2A2 | 0.19499690 |
| 95 | PRKACB | 0.19062520 |
| 96 | TTK | 0.19019141 |
| 97 | IGF1R | 0.18395342 |
| 98 | IRAK1 | 0.17749521 |
| 99 | PAK1 | 0.15586835 |
| 100 | CDK5 | 0.14916295 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.60175984 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.26460976 |
| 3 | Proteasome_Homo sapiens_hsa03050 | 4.09225516 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.65019754 |
| 5 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 3.36686975 |
| 6 | Protein export_Homo sapiens_hsa03060 | 2.99018863 |
| 7 | Asthma_Homo sapiens_hsa05310 | 2.63906091 |
| 8 | Huntingtons disease_Homo sapiens_hsa05016 | 2.55371503 |
| 9 | RNA polymerase_Homo sapiens_hsa03020 | 2.48330187 |
| 10 | Alzheimers disease_Homo sapiens_hsa05010 | 2.32697605 |
| 11 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 2.22714400 |
| 12 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.98134344 |
| 13 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.95895905 |
| 14 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.70177299 |
| 15 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.66730972 |
| 16 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.63270126 |
| 17 | RNA degradation_Homo sapiens_hsa03018 | 1.55612601 |
| 18 | Homologous recombination_Homo sapiens_hsa03440 | 1.55311580 |
| 19 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.51574850 |
| 20 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.50455829 |
| 21 | Taste transduction_Homo sapiens_hsa04742 | 1.50451075 |
| 22 | Allograft rejection_Homo sapiens_hsa05330 | 1.44823701 |
| 23 | Alcoholism_Homo sapiens_hsa05034 | 1.40980598 |
| 24 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.39681604 |
| 25 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.38757365 |
| 26 | Nicotine addiction_Homo sapiens_hsa05033 | 1.36231129 |
| 27 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.30828288 |
| 28 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.27960021 |
| 29 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.23844139 |
| 30 | Phototransduction_Homo sapiens_hsa04744 | 1.22418987 |
| 31 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.21820253 |
| 32 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.21473912 |
| 33 | Mismatch repair_Homo sapiens_hsa03430 | 1.11803036 |
| 34 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.08000821 |
| 35 | Peroxisome_Homo sapiens_hsa04146 | 1.06075702 |
| 36 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.98230229 |
| 37 | Spliceosome_Homo sapiens_hsa03040 | 0.95920740 |
| 38 | Purine metabolism_Homo sapiens_hsa00230 | 0.90487262 |
| 39 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.88442602 |
| 40 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.87505990 |
| 41 | Basal transcription factors_Homo sapiens_hsa03022 | 0.87463587 |
| 42 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.86967129 |
| 43 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.85891073 |
| 44 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.85310360 |
| 45 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.84542460 |
| 46 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.84170466 |
| 47 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.83089638 |
| 48 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.80992741 |
| 49 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.78687907 |
| 50 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.77198388 |
| 51 | DNA replication_Homo sapiens_hsa03030 | 0.75799763 |
| 52 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.75341512 |
| 53 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.75010786 |
| 54 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.73533012 |
| 55 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.73341717 |
| 56 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.70139201 |
| 57 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.70098886 |
| 58 | Olfactory transduction_Homo sapiens_hsa04740 | 0.69445382 |
| 59 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.68842826 |
| 60 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.66623940 |
| 61 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.65496679 |
| 62 | RNA transport_Homo sapiens_hsa03013 | 0.63528013 |
| 63 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.62209334 |
| 64 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.61375990 |
| 65 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.59799752 |
| 66 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.59642623 |
| 67 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.59296687 |
| 68 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.54577017 |
| 69 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.53173549 |
| 70 | Metabolic pathways_Homo sapiens_hsa01100 | 0.52061440 |
| 71 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.50198603 |
| 72 | Retinol metabolism_Homo sapiens_hsa00830 | 0.49154740 |
| 73 | Circadian entrainment_Homo sapiens_hsa04713 | 0.48856379 |
| 74 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.48380865 |
| 75 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.44420412 |
| 76 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.44083920 |
| 77 | Cocaine addiction_Homo sapiens_hsa05030 | 0.42564756 |
| 78 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.42107320 |
| 79 | Carbon metabolism_Homo sapiens_hsa01200 | 0.41184508 |
| 80 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.40903740 |
| 81 | Base excision repair_Homo sapiens_hsa03410 | 0.38436837 |
| 82 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.38098846 |
| 83 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.37405322 |
| 84 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.36337390 |
| 85 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.35300531 |
| 86 | Leishmaniasis_Homo sapiens_hsa05140 | 0.34310602 |
| 87 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.33498371 |
| 88 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.32928391 |
| 89 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.32843620 |
| 90 | GABAergic synapse_Homo sapiens_hsa04727 | 0.29562236 |
| 91 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.27904244 |
| 92 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.27504448 |
| 93 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.25714771 |
| 94 | Morphine addiction_Homo sapiens_hsa05032 | 0.25683205 |
| 95 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.24869947 |
| 96 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.24426491 |
| 97 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.24165778 |
| 98 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.23028689 |
| 99 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.21349205 |
| 100 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.21252476 |

