PABPC4L

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mesenchymal cell differentiation involved in kidney development (GO:0072161)6.70402074
2mesenchymal cell differentiation involved in renal system development (GO:2001012)6.70402074
3regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450916.17512824
4cell differentiation involved in metanephros development (GO:0072202)5.94245110
5glomerulus development (GO:0032835)4.93492820
6extracellular fibril organization (GO:0043206)4.68071297
7respiratory tube development (GO:0030323)4.37667512
8fibril organization (GO:0097435)4.21204533
9nuclear pore complex assembly (GO:0051292)4.01756376
10regulation of cardioblast differentiation (GO:0051890)3.97510073
11paraxial mesoderm development (GO:0048339)3.91626726
12response to UV-B (GO:0010224)3.89610868
13protein localization to kinetochore (GO:0034501)3.83933285
14anterior/posterior axis specification, embryo (GO:0008595)3.71405137
15notochord development (GO:0030903)3.68264612
16definitive hemopoiesis (GO:0060216)3.66965042
17nuclear pore organization (GO:0006999)3.64982721
18mitotic sister chromatid cohesion (GO:0007064)3.62746251
19UV protection (GO:0009650)3.61198192
20negative regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043518)3.60931319
21mesenchymal cell differentiation (GO:0048762)3.55802248
22protein localization to chromosome, centromeric region (GO:0071459)3.53339686
23ribosomal small subunit assembly (GO:0000028)3.53259295
24mesonephros development (GO:0001823)3.49967543
25ventricular cardiac muscle cell development (GO:0055015)3.48344283
26cell differentiation involved in kidney development (GO:0061005)3.40357040
27cartilage morphogenesis (GO:0060536)3.40318748
28cell migration involved in heart development (GO:0060973)3.36843448
29lung vasculature development (GO:0060426)3.34425504
30cell proliferation involved in metanephros development (GO:0072203)3.32028260
31mitotic metaphase plate congression (GO:0007080)3.31083749
32embryonic digestive tract morphogenesis (GO:0048557)3.30766836
33DNA unwinding involved in DNA replication (GO:0006268)3.29876612
34metanephric mesenchyme development (GO:0072075)3.29223904
35facial nerve structural organization (GO:0021612)3.26574121
36metaphase plate congression (GO:0051310)3.23632312
37primitive streak formation (GO:0090009)3.20983775
38mitotic sister chromatid segregation (GO:0000070)3.19238186
39DNA ligation (GO:0006266)3.18867077
40histone exchange (GO:0043486)3.18780419
41neural crest cell development (GO:0014032)3.18202571
42kidney mesenchyme development (GO:0072074)3.16472649
43ureteric bud development (GO:0001657)3.15532680
44negative regulation of keratinocyte proliferation (GO:0010839)3.14420791
45mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337)3.13798895
46sister chromatid segregation (GO:0000819)3.13071956
47epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)3.12652184
48organ formation (GO:0048645)3.12208070
49cell proliferation involved in kidney development (GO:0072111)3.08289095
50regulation of Wnt signaling pathway involved in heart development (GO:0003307)3.07140533
51proteasome assembly (GO:0043248)3.05633013
52viral mRNA export from host cell nucleus (GO:0046784)3.04752387
53lymph vessel development (GO:0001945)3.02600312
54diaphragm development (GO:0060539)3.01907124
55cell surface receptor signaling pathway involved in heart development (GO:0061311)3.00966033
56cullin deneddylation (GO:0010388)2.98595838
57mesonephric tubule development (GO:0072164)2.97539412
58regulation of non-canonical Wnt signaling pathway (GO:2000050)2.96977340
59DNA replication-independent nucleosome assembly (GO:0006336)2.96832422
60DNA replication-independent nucleosome organization (GO:0034724)2.96832422
61mesenchymal cell development (GO:0014031)2.96447279
62regulation of transforming growth factor beta2 production (GO:0032909)2.96379244
63pore complex assembly (GO:0046931)2.94937833
64DNA replication checkpoint (GO:0000076)2.92846228
65kinetochore organization (GO:0051383)2.92623039
66smooth muscle tissue development (GO:0048745)2.90378975
67regulation of transcription from RNA polymerase II promoter involved in heart development (GO:1901212.90235451
68heterochromatin organization (GO:0070828)2.89769655
69outer ear morphogenesis (GO:0042473)2.89364209
70negative regulation of stem cell proliferation (GO:2000647)2.88843661
71mesenchymal cell proliferation (GO:0010463)2.87761608
72negative regulation of cell fate specification (GO:0009996)2.84695791
73DNA replication-dependent nucleosome organization (GO:0034723)2.84304297
74DNA replication-dependent nucleosome assembly (GO:0006335)2.84304297
75DNA damage response, detection of DNA damage (GO:0042769)2.84239078
76establishment of integrated proviral latency (GO:0075713)2.83841074
77mesonephric epithelium development (GO:0072163)2.83330076
78negative regulation of chondrocyte differentiation (GO:0032331)2.82376308
79anterior/posterior axis specification (GO:0009948)2.80985479
80kinetochore assembly (GO:0051382)2.80543818
81regulation of centriole replication (GO:0046599)2.80054710
82branching involved in ureteric bud morphogenesis (GO:0001658)2.79509571
83negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948)2.79402755
84CENP-A containing nucleosome assembly (GO:0034080)2.78852245
85negative regulation of androgen receptor signaling pathway (GO:0060766)2.78691967
86regulation of pigment cell differentiation (GO:0050932)2.78645104
87metanephros development (GO:0001656)2.78263892
88DNA strand elongation (GO:0022616)2.75673530
89negative regulation of DNA repair (GO:0045738)2.75082950
90cell migration involved in gastrulation (GO:0042074)2.74353737
91regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.72360141
92embryonic skeletal joint morphogenesis (GO:0060272)2.71730937
93dorsal/ventral axis specification (GO:0009950)2.71372592
94regulation of mesoderm development (GO:2000380)2.70571642
95regulation of stem cell maintenance (GO:2000036)2.69580472
96cell migration involved in sprouting angiogenesis (GO:0002042)2.68236299
97respiratory chain complex IV assembly (GO:0008535)2.67713165
98DNA strand elongation involved in DNA replication (GO:0006271)2.67648248
99embryonic foregut morphogenesis (GO:0048617)2.67286850
100cytochrome complex assembly (GO:0017004)2.66742038
101endothelial cell morphogenesis (GO:0001886)2.66036578
102protein deneddylation (GO:0000338)2.65187004
103peptidyl-lysine dimethylation (GO:0018027)2.64284550
104kidney morphogenesis (GO:0060993)2.63478575
105negative regulation of DNA-dependent DNA replication (GO:2000104)2.63381310
106establishment of apical/basal cell polarity (GO:0035089)2.63363906
107sequestering of extracellular ligand from receptor (GO:0035581)2.62631974
108chromatin remodeling at centromere (GO:0031055)2.62062895
109cellular protein complex localization (GO:0034629)2.61771742
110outflow tract septum morphogenesis (GO:0003148)2.61366865
111platelet dense granule organization (GO:0060155)2.61098276
112establishment of chromosome localization (GO:0051303)2.60369489
113midgut development (GO:0007494)2.60323455
114extracellular matrix assembly (GO:0085029)2.60218160
115embryonic heart tube development (GO:0035050)2.59820584
116ventricular septum development (GO:0003281)2.59091938
117uterus development (GO:0060065)2.58689020
118proximal/distal pattern formation (GO:0009954)2.57674826
119endocardial cushion development (GO:0003197)2.57332470
120regulation of DNA endoreduplication (GO:0032875)2.56806688
121regulation of vitamin D biosynthetic process (GO:0060556)2.56548064
122mesenchyme morphogenesis (GO:0072132)2.56228545
123positive regulation of cardiac muscle cell proliferation (GO:0060045)2.55141608
124chondrocyte proliferation (GO:0035988)2.51977953
125regulation of glucocorticoid metabolic process (GO:0031943)2.51534928
126atrial septum morphogenesis (GO:0060413)2.51379713
127cardiac epithelial to mesenchymal transition (GO:0060317)2.50898977
128hippo signaling (GO:0035329)2.50179377
129heart contraction (GO:0060047)2.50173286
130heart process (GO:0003015)2.50173286
131male genitalia development (GO:0030539)2.48970594
132positive regulation of cardiac muscle tissue development (GO:0055025)2.48805741
133skeletal muscle organ development (GO:0060538)2.48335481
134ATP-dependent chromatin remodeling (GO:0043044)2.47070839
135forelimb morphogenesis (GO:0035136)2.46923298
136artery development (GO:0060840)2.46847781
137regulation of cell fate specification (GO:0042659)2.46437769
138organ induction (GO:0001759)2.46376590
139lymphangiogenesis (GO:0001946)2.45050400
140stem cell development (GO:0048864)2.44691396
141mitotic G2/M transition checkpoint (GO:0044818)2.44091581
142branching involved in prostate gland morphogenesis (GO:0060442)2.43599845
143protein complex localization (GO:0031503)2.42943993
144reproductive system development (GO:0061458)2.42856853
145mitotic chromosome condensation (GO:0007076)2.42342926
146positive regulation of SMAD protein import into nucleus (GO:0060391)2.42090840
147negative regulation of cardiac muscle cell apoptotic process (GO:0010667)2.41227984
148extracellular negative regulation of signal transduction (GO:1900116)2.40962453
149extracellular regulation of signal transduction (GO:1900115)2.40962453
150pre-miRNA processing (GO:0031054)2.40766999
151mesenchymal to epithelial transition (GO:0060231)2.40603838
152embryonic axis specification (GO:0000578)2.40192972
153phagocytosis, engulfment (GO:0006911)2.39629456
154regulation of cardiac muscle tissue development (GO:0055024)2.39499800
155G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071992.39430353
156regulation of centrosome cycle (GO:0046605)2.38222590
157cranial nerve morphogenesis (GO:0021602)2.38089358
158retina vasculature morphogenesis in camera-type eye (GO:0061299)2.37971796
159DNA replication initiation (GO:0006270)2.37000539
160ventricular trabecula myocardium morphogenesis (GO:0003222)2.36177106
161lung morphogenesis (GO:0060425)2.35364639
162negative regulation of phagocytosis (GO:0050765)2.34935012
163termination of RNA polymerase I transcription (GO:0006363)2.33488573
164cardiac septum morphogenesis (GO:0060411)2.33176617
165mesodermal cell differentiation (GO:0048333)2.32857931
166ribosome assembly (GO:0042255)2.32742795
167regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.32718291
168kidney epithelium development (GO:0072073)2.32660471
169regulation of heart morphogenesis (GO:2000826)2.31772500
170maturation of SSU-rRNA (GO:0030490)2.31408223
171gap junction assembly (GO:0016264)2.30776509
172regulation of mesenchymal cell apoptotic process (GO:2001053)2.30602063
173spleen development (GO:0048536)2.30453934
174pattern specification involved in kidney development (GO:0061004)2.30438990
175poly(A)+ mRNA export from nucleus (GO:0016973)2.30289491
176regulation of keratinocyte proliferation (GO:0010837)2.29494301
177spindle checkpoint (GO:0031577)2.29272111
178negative regulation of cardiac muscle tissue development (GO:0055026)2.29018192
179bundle of His cell to Purkinje myocyte communication (GO:0086069)2.28894455
180myoblast migration (GO:0051451)2.27880861
181embryonic forelimb morphogenesis (GO:0035115)2.27739782
182chromatin assembly or disassembly (GO:0006333)2.27472348
183palate development (GO:0060021)2.26475703
184negative regulation of G2/M transition of mitotic cell cycle (GO:0010972)2.25990560
185protein K11-linked ubiquitination (GO:0070979)2.25012674

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse8.22699640
2E2F7_22180533_ChIP-Seq_HELA_Human6.40821489
3RBPJ_22232070_ChIP-Seq_NCS_Mouse5.89711278
4TP63_19390658_ChIP-ChIP_HaCaT_Human4.03268815
5FOXM1_23109430_ChIP-Seq_U2OS_Human3.41694277
6KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.09898351
7CHD7_19251738_ChIP-ChIP_MESCs_Mouse3.05609690
8ELK1_19687146_ChIP-ChIP_HELA_Human2.64515616
9SALL1_21062744_ChIP-ChIP_HESCs_Human2.53343527
10GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.51062976
11EST1_17652178_ChIP-ChIP_JURKAT_Human2.46195087
12POU5F1_16153702_ChIP-ChIP_HESCs_Human2.43817343
13MYC_18555785_ChIP-Seq_MESCs_Mouse2.33661418
14ELF1_17652178_ChIP-ChIP_JURKAT_Human2.29098029
15E2F4_17652178_ChIP-ChIP_JURKAT_Human2.28616980
16CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.06057553
17FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.02586026
18PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.98170925
19CREB1_15753290_ChIP-ChIP_HEK293T_Human1.96349331
20FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.94010241
21CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.85618602
22BP1_19119308_ChIP-ChIP_Hs578T_Human1.84246641
23* EWS_26573619_Chip-Seq_HEK293_Human1.82677192
24SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.81896016
25SRF_21415370_ChIP-Seq_HL-1_Mouse1.81102213
26GABP_17652178_ChIP-ChIP_JURKAT_Human1.78361696
27HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.75526291
28NELFA_20434984_ChIP-Seq_ESCs_Mouse1.73000212
29TAF15_26573619_Chip-Seq_HEK293_Human1.67065495
30* FUS_26573619_Chip-Seq_HEK293_Human1.66383068
31MYC_19030024_ChIP-ChIP_MESCs_Mouse1.65340043
32CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.63910847
33MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.63580017
34HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.62561217
35HOXB4_20404135_ChIP-ChIP_EML_Mouse1.61251220
36HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.60886134
37WT1_19549856_ChIP-ChIP_CCG9911_Human1.60840904
38IRF1_19129219_ChIP-ChIP_H3396_Human1.58888651
39PADI4_21655091_ChIP-ChIP_MCF-7_Human1.53557374
40KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.51619884
41SALL4_18804426_ChIP-ChIP_XEN_Mouse1.49578253
42SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.47999523
43MYCN_18555785_ChIP-Seq_MESCs_Mouse1.46430936
44SOX2_18555785_ChIP-Seq_MESCs_Mouse1.45385990
45TRIM28_21343339_ChIP-Seq_HEK293_Human1.45286366
46NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.43735134
47EED_16625203_ChIP-ChIP_MESCs_Mouse1.43222522
48RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.42957959
49PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.40775788
50YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.39432242
51MYC_18940864_ChIP-ChIP_HL60_Human1.39421544
52AR_21909140_ChIP-Seq_LNCAP_Human1.39419036
53ZFX_18555785_ChIP-Seq_MESCs_Mouse1.37135750
54JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.36639403
55BMI1_23680149_ChIP-Seq_NPCS_Mouse1.34671788
56EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.33640163
57E2F1_21310950_ChIP-Seq_MCF-7_Human1.32638944
58TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.32511096
59SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.31365495
60VDR_23849224_ChIP-Seq_CD4+_Human1.30814418
61CBX2_27304074_Chip-Seq_ESCs_Mouse1.30112109
62SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.27915194
63PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.26517350
64POU3F2_20337985_ChIP-ChIP_501MEL_Human1.26366931
65ERG_20887958_ChIP-Seq_HPC-7_Mouse1.26155096
66PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.25545770
67TTF2_22483619_ChIP-Seq_HELA_Human1.23457599
68TCF3_18692474_ChIP-Seq_MEFs_Mouse1.22153449
69E2F1_18555785_ChIP-Seq_MESCs_Mouse1.21926686
70MYC_18358816_ChIP-ChIP_MESCs_Mouse1.21589358
71ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.21022101
72FLI1_27457419_Chip-Seq_LIVER_Mouse1.19934692
73GATA4_21415370_ChIP-Seq_HL-1_Mouse1.18856791
74NOTCH1_21737748_ChIP-Seq_TLL_Human1.18237176
75KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.17689892
76TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.15567765
77SMAD_19615063_ChIP-ChIP_OVARY_Human1.12811828
78FOXP3_21729870_ChIP-Seq_TREG_Human1.11921405
79SMAD3_21741376_ChIP-Seq_EPCs_Human1.10575801
80DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.10464272
81EP300_21415370_ChIP-Seq_HL-1_Mouse1.09422660
82SOX2_16153702_ChIP-ChIP_HESCs_Human1.09227646
83RNF2_27304074_Chip-Seq_NSC_Mouse1.08537150
84POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.08496796
85SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.06345535
86FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.06103452
87PCGF2_27294783_Chip-Seq_ESCs_Mouse1.03179773
88ZFP57_27257070_Chip-Seq_ESCs_Mouse1.02764463
89TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.02461143
90CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.01240247
91MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.00647248
92POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.99217644
93EOMES_21245162_ChIP-Seq_HESCs_Human0.98525191
94SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.98103504
95NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.97889145
96BRD4_25478319_ChIP-Seq_HGPS_Human0.97414280
97RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.96507662
98POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.95567751
99ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.94148417
100TBX3_20139965_ChIP-Seq_ESCs_Mouse0.93937444
101CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.93586952
102TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.93267738
103TBX3_20139965_ChIP-Seq_MESCs_Mouse0.93255054
104NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.93123347
105SOX17_20123909_ChIP-Seq_XEN_Mouse0.92557438
106NRF2_20460467_ChIP-Seq_MEFs_Mouse0.92308781
107NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.92308781
108* P300_19829295_ChIP-Seq_ESCs_Human0.92136796
109TCF3_18692474_ChIP-Seq_MESCs_Mouse0.91653033
110SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.91493623
111FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.91421312
112CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.90935371
113DCP1A_22483619_ChIP-Seq_HELA_Human0.90890985
114PIAS1_25552417_ChIP-Seq_VCAP_Human0.90419214
115* EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.89583299
116CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.89136254
117LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.88478602
118ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.88353754
119NANOG_16153702_ChIP-ChIP_HESCs_Human0.88052729
120ETS1_20019798_ChIP-Seq_JURKAT_Human0.87994278
121MYC_19079543_ChIP-ChIP_MESCs_Mouse0.87165612
122FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.86341362
123XRN2_22483619_ChIP-Seq_HELA_Human0.85352374
124RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.84970755
125THAP11_20581084_ChIP-Seq_MESCs_Mouse0.84169372
126ESR1_20079471_ChIP-ChIP_T-47D_Human0.83772957
127KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.83358683
128KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.83358683
129KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.83358683
130ISL1_27105846_Chip-Seq_CPCs_Mouse0.82238356
131ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.81851576
132NFI_21473784_ChIP-Seq_ESCs_Mouse0.81014630
133GBX2_23144817_ChIP-Seq_PC3_Human0.80319668
134ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.80138698
135MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.79605798

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003890_abnormal_embryonic-extraembry3.39036215
2MP0002249_abnormal_larynx_morphology2.98843324
3MP0002938_white_spotting2.96835216
4MP0003122_maternal_imprinting2.82786727
5MP0003123_paternal_imprinting2.77911772
6MP0009697_abnormal_copulation2.56597499
7MP0009379_abnormal_foot_pigmentation2.52545230
8MP0009250_abnormal_appendicular_skeleto2.50797505
9MP0003315_abnormal_perineum_morphology2.50486912
10MP0003121_genomic_imprinting2.50141185
11MP0002396_abnormal_hematopoietic_system2.49912467
12MP0000049_abnormal_middle_ear2.47944592
13MP0010030_abnormal_orbit_morphology2.46072068
14MP0003942_abnormal_urinary_system2.37906636
15MP0005503_abnormal_tendon_morphology2.33732747
16MP0003385_abnormal_body_wall2.33658660
17MP0003115_abnormal_respiratory_system2.33539667
18MP0002282_abnormal_trachea_morphology2.32103465
19MP0001879_abnormal_lymphatic_vessel2.30532504
20MP0005367_renal/urinary_system_phenotyp2.25774150
21MP0000516_abnormal_urinary_system2.25774150
22MP0002132_abnormal_respiratory_system2.17982800
23MP0005187_abnormal_penis_morphology2.09617485
24MP0000566_synostosis2.06869734
25MP0008058_abnormal_DNA_repair2.03946532
26MP0005623_abnormal_meninges_morphology2.01420556
27MP0008007_abnormal_cellular_replicative1.98080713
28MP0006292_abnormal_olfactory_placode1.96459969
29MP0001188_hyperpigmentation1.90249224
30MP0005409_darkened_coat_color1.83327548
31MP0003943_abnormal_hepatobiliary_system1.82630930
32MP0004272_abnormal_basement_membrane1.81001594
33MP0000537_abnormal_urethra_morphology1.80694513
34MP0002084_abnormal_developmental_patter1.80431724
35MP0002009_preneoplasia1.79829711
36MP0005275_abnormal_skin_tensile1.75677181
37MP0009053_abnormal_anal_canal1.73955052
38MP0003567_abnormal_fetal_cardiomyocyte1.65378042
39MP0003111_abnormal_nucleus_morphology1.64428374
40MP0003279_aneurysm1.64267282
41MP0002697_abnormal_eye_size1.61909412
42MP0001672_abnormal_embryogenesis/_devel1.60395997
43MP0005380_embryogenesis_phenotype1.60395997
44MP0003941_abnormal_skin_development1.59834639
45MP0005508_abnormal_skeleton_morphology1.58142981
46MP0003937_abnormal_limbs/digits/tail_de1.56707844
47MP0005084_abnormal_gallbladder_morpholo1.55539000
48MP0000534_abnormal_ureter_morphology1.55367373
49MP0000372_irregular_coat_pigmentation1.50809270
50MP0005171_absent_coat_pigmentation1.50209347
51MP0003693_abnormal_embryo_hatching1.49876639
52MP0003984_embryonic_growth_retardation1.49498611
53MP0002088_abnormal_embryonic_growth/wei1.46213645
54MP0010368_abnormal_lymphatic_system1.46154878
55MP0002085_abnormal_embryonic_tissue1.44906845
56MP0008438_abnormal_cutaneous_collagen1.44706592
57MP0005248_abnormal_Harderian_gland1.43257408
58MP0001730_embryonic_growth_arrest1.43041677
59MP0001299_abnormal_eye_distance/1.42595534
60MP0010094_abnormal_chromosome_stability1.42462814
61MP0000678_abnormal_parathyroid_gland1.39656687
62MP0003705_abnormal_hypodermis_morpholog1.39640344
63MP0003011_delayed_dark_adaptation1.38568285
64MP0006054_spinal_hemorrhage1.33857567
65MP0002160_abnormal_reproductive_system1.31997496
66MP0002233_abnormal_nose_morphology1.31636227
67MP0004808_abnormal_hematopoietic_stem1.30210595
68MP0002177_abnormal_outer_ear1.27435850
69MP0002109_abnormal_limb_morphology1.26014326
70MP0001697_abnormal_embryo_size1.25710462
71MP0002095_abnormal_skin_pigmentation1.25157831
72MP0003119_abnormal_digestive_system1.23688510
73MP0002877_abnormal_melanocyte_morpholog1.23149785
74MP0002092_abnormal_eye_morphology1.21371240
75MP0000767_abnormal_smooth_muscle1.21244222
76MP0001175_abnormal_lung_morphology1.20198516
77MP0000015_abnormal_ear_pigmentation1.19383567
78MP0002086_abnormal_extraembryonic_tissu1.19085081
79MP0000462_abnormal_digestive_system1.17081975
80MP0003755_abnormal_palate_morphology1.14646685
81MP0003935_abnormal_craniofacial_develop1.13605632
82MP0002638_abnormal_pupillary_reflex1.13577348
83MP0002932_abnormal_joint_morphology1.13402466
84MP0000350_abnormal_cell_proliferation1.12665344
85MP0001293_anophthalmia1.11493605
86MP0001119_abnormal_female_reproductive1.09776289
87MP0010352_gastrointestinal_tract_polyps1.07027663
88MP0000733_abnormal_muscle_development1.06425092
89MP0003828_pulmonary_edema1.02684304
90MP0004957_abnormal_blastocyst_morpholog1.02661557
91MP0005197_abnormal_uvea_morphology1.01946425
92MP0003077_abnormal_cell_cycle1.01891691
93MP0000681_abnormal_thyroid_gland1.01148331
94MP0002080_prenatal_lethality1.00243102
95MP0000163_abnormal_cartilage_morphology0.97896783
96MP0002127_abnormal_cardiovascular_syste0.96276118
97MP0009672_abnormal_birth_weight0.91806245
98MP0008057_abnormal_DNA_replication0.91277493
99MP0008932_abnormal_embryonic_tissue0.89483397
100MP0005408_hypopigmentation0.87462335
101MP0002115_abnormal_skeleton_extremities0.86920929
102MP0006138_congestive_heart_failure0.86469275
103MP0003283_abnormal_digestive_organ0.85730565
104MP0000749_muscle_degeneration0.84836631
105MP0001177_atelectasis0.84563206
106MP0002114_abnormal_axial_skeleton0.84445293
107MP0001286_abnormal_eye_development0.84189279
108MP0005389_reproductive_system_phenotype0.83586514
109MP0000762_abnormal_tongue_morphology0.83321988
110MP0006072_abnormal_retinal_apoptosis0.83148250
111MP0001661_extended_life_span0.82924169
112MP0009384_cardiac_valve_regurgitation0.82397041
113MP0002116_abnormal_craniofacial_bone0.82040078
114MP0004147_increased_porphyrin_level0.81083780
115MP0002102_abnormal_ear_morphology0.80870090
116MP0005257_abnormal_intraocular_pressure0.80529093
117MP0005391_vision/eye_phenotype0.80083168
118MP0002111_abnormal_tail_morphology0.79726730
119MP0003787_abnormal_imprinting0.78985098
120MP0010307_abnormal_tumor_latency0.78639658
121MP0000432_abnormal_head_morphology0.77660240
122MP0009703_decreased_birth_body0.77175799
123MP0002108_abnormal_muscle_morphology0.76275046
124MP0003786_premature_aging0.76030928
125MP0004197_abnormal_fetal_growth/weight/0.75819692
126MP0002128_abnormal_blood_circulation0.75776143
127MP0003950_abnormal_plasma_membrane0.75255423
128MP0000428_abnormal_craniofacial_morphol0.74379852
129MP0003136_yellow_coat_color0.73639687
130MP0005076_abnormal_cell_differentiation0.73069671
131MP0004215_abnormal_myocardial_fiber0.72314130
132MP0001915_intracranial_hemorrhage0.72099103
133MP0000613_abnormal_salivary_gland0.71922884
134MP0002925_abnormal_cardiovascular_devel0.70798621
135MP0002113_abnormal_skeleton_development0.70779991
136MP0004782_abnormal_surfactant_physiolog0.70323487
137MP0004133_heterotaxia0.70246609
138MP0001270_distended_abdomen0.70158329
139MP0005390_skeleton_phenotype0.69562550
140MP0008877_abnormal_DNA_methylation0.68452997

Predicted human phenotypes

RankGene SetZ-score
1Embryonal renal neoplasm (HP:0011794)4.08483430
2Hypothermia (HP:0002045)3.92839334
3Enlarged kidneys (HP:0000105)3.73042560
4Missing ribs (HP:0000921)3.46959218
5Premature rupture of membranes (HP:0001788)3.43527179
6Syringomyelia (HP:0003396)3.41344919
7Spinal cord lesions (HP:0100561)3.41344919
8Myelomeningocele (HP:0002475)3.22896459
9White forelock (HP:0002211)3.21349087
10Abnormal lung lobation (HP:0002101)3.19116697
11Patchy hypopigmentation of hair (HP:0011365)3.11173627
12Hypoplastic left heart (HP:0004383)3.03704827
13Metaphyseal dysplasia (HP:0100255)3.02328369
14Bell-shaped thorax (HP:0001591)2.97761652
15Midline defect of the nose (HP:0004122)2.96789291
16Type I transferrin isoform profile (HP:0003642)2.94465507
17Tracheomalacia (HP:0002779)2.86660511
18Abnormality of dentin (HP:0010299)2.81130283
19Asymmetry of the thorax (HP:0001555)2.75366312
20Short 4th metacarpal (HP:0010044)2.74947361
21Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.74947361
22Nephroblastoma (Wilms tumor) (HP:0002667)2.71553023
23Diastasis recti (HP:0001540)2.69097499
24Colon cancer (HP:0003003)2.67348054
25Coronal craniosynostosis (HP:0004440)2.64298719
26Hepatoblastoma (HP:0002884)2.63101436
27Pancreatic fibrosis (HP:0100732)2.60977548
28Short middle phalanx of the 5th finger (HP:0004220)2.57776043
29Reduced antithrombin III activity (HP:0001976)2.54008216
30Microglossia (HP:0000171)2.48208420
31True hermaphroditism (HP:0010459)2.47349247
32Facial cleft (HP:0002006)2.46749049
33Renal dysplasia (HP:0000110)2.46412509
34Supernumerary spleens (HP:0009799)2.44302584
35Pulmonary artery stenosis (HP:0004415)2.41747199
36Pancreatic islet-cell hyperplasia (HP:0004510)2.41492359
37Abnormality of the phalanges of the hallux (HP:0010057)2.41487172
38Hypoplastic heart (HP:0001961)2.38903765
39Proximal placement of thumb (HP:0009623)2.38861389
40Hypochromic microcytic anemia (HP:0004840)2.38810404
41Abnormality of the lumbar spine (HP:0100712)2.35772808
42Deviation of the thumb (HP:0009603)2.34194075
43Abnormal foot bone ossification (HP:0010675)2.33396753
44Heterochromia iridis (HP:0001100)2.32628205
45Abnormality of the umbilical cord (HP:0010881)2.31636683
46Abnormality of the 2nd finger (HP:0004100)2.31464476
47Partial duplication of the phalanx of hand (HP:0009999)2.30436986
48Cutaneous finger syndactyly (HP:0010554)2.29930177
49Abnormality of the nasolacrimal system (HP:0000614)2.28913707
50Abnormal tarsal ossification (HP:0008369)2.28261381
51Ectopic anus (HP:0004397)2.27771309
52Dry hair (HP:0011359)2.26382324
53Optic nerve coloboma (HP:0000588)2.22559116
54Abnormal pancreas size (HP:0012094)2.21936809
55Congenital sensorineural hearing impairment (HP:0008527)2.20999675
56Abnormality of incisor morphology (HP:0011063)2.19960083
57Renal duplication (HP:0000075)2.18035013
58Abnormality of the lacrimal duct (HP:0011481)2.17942403
59Mesomelia (HP:0003027)2.14368367
60Transposition of the great arteries (HP:0001669)2.14261955
61Abnormal connection of the cardiac segments (HP:0011545)2.14261955
62Abnormal ventriculo-arterial connection (HP:0011563)2.14261955
63Adrenal hypoplasia (HP:0000835)2.13542433
64Soft skin (HP:0000977)2.11321050
65Chromosomal breakage induced by crosslinking agents (HP:0003221)2.09902771
66Short hallux (HP:0010109)2.09282293
67Cutaneous syndactyly (HP:0012725)2.08998140
68Short middle phalanx of finger (HP:0005819)2.08694475
69Aortic dissection (HP:0002647)2.08258396
70Absent radius (HP:0003974)2.06420846
71Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)2.04298738
72Bifid tongue (HP:0010297)2.03795374
73Increased number of teeth (HP:0011069)2.02921024
74Abnormality of the middle phalanx of the 5th finger (HP:0004219)2.00934172
75Abnormality of the incisor (HP:0000676)2.00243225
76Hyperinsulinemic hypoglycemia (HP:0000825)2.00040951
77Hypoglycemic seizures (HP:0002173)1.99631930
78Abnormality of the fetal cardiovascular system (HP:0010948)1.99523864
79Abnormal umbilical cord blood vessels (HP:0011403)1.99523864
80Single umbilical artery (HP:0001195)1.99523864
81Congenital malformation of the right heart (HP:0011723)1.98602618
82Double outlet right ventricle (HP:0001719)1.98602618
83Preaxial hand polydactyly (HP:0001177)1.96927884
84Abnormality of the 4th metacarpal (HP:0010012)1.95424832
85Abnormality of the columella (HP:0009929)1.92777921
86Renal hypoplasia (HP:0000089)1.90594753
87Calcaneovalgus deformity (HP:0001848)1.90018021
88Partial duplication of thumb phalanx (HP:0009944)1.89849844
89Short 5th finger (HP:0009237)1.89617818
90Abdominal situs inversus (HP:0003363)1.88651235
91Abnormality of abdominal situs (HP:0011620)1.88651235
92Preaxial foot polydactyly (HP:0001841)1.88497851
93Volvulus (HP:0002580)1.88222998
94Abnormal number of incisors (HP:0011064)1.87904220
95Aplasia/Hypoplasia of the hallux (HP:0008362)1.87473774
96Aplasia involving forearm bones (HP:0009822)1.86930959
97Absent forearm bone (HP:0003953)1.86930959
98Spinal rigidity (HP:0003306)1.85217738
99Neoplasm of the liver (HP:0002896)1.85183443
100Rimmed vacuoles (HP:0003805)1.84354881
101Abnormality of the ileum (HP:0001549)1.84351068
102Aplasia/Hypoplasia of the tongue (HP:0010295)1.84296351
103Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)1.83712581
104Abnormality of the phalanges of the 5th finger (HP:0004213)1.83529220
105Back pain (HP:0003418)1.83503000
106Aplasia/hypoplasia of the humerus (HP:0006507)1.83138839
107Aplasia/Hypoplasia of the tibia (HP:0005772)1.82730874
108Long foot (HP:0001833)1.82517082
109Shawl scrotum (HP:0000049)1.81965079
110Aplasia/Hypoplasia of the uvula (HP:0010293)1.81184309
111Short clavicles (HP:0000894)1.81163598
112Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.81053033
113Abnormal protein N-linked glycosylation (HP:0012347)1.81053033
114Abnormal protein glycosylation (HP:0012346)1.81053033
115Abnormal glycosylation (HP:0012345)1.81053033
116Cortical dysplasia (HP:0002539)1.80983535
117Ectopic kidney (HP:0000086)1.80610046
118Abnormality of the parietal bone (HP:0002696)1.80105746
119Short humerus (HP:0005792)1.79841983
120Atrophic scars (HP:0001075)1.79813920
121Abnormality of the calcaneus (HP:0008364)1.79281045
122Abnormality of chromosome stability (HP:0003220)1.78866474
123Patent foramen ovale (HP:0001655)1.78685006
124Occipital encephalocele (HP:0002085)1.78257912
125Septate vagina (HP:0001153)1.77280234
12611 pairs of ribs (HP:0000878)1.76983948
127Abnormality of the middle phalanges of the toes (HP:0010183)1.76674356
128Pancreatic cysts (HP:0001737)1.75894931
129Chromsome breakage (HP:0040012)1.73748132
130Morphological abnormality of the middle ear (HP:0008609)1.73580100
131Abnormality of the ischium (HP:0003174)1.72805701
132Short tibia (HP:0005736)1.72684006
133Abnormality of the pulmonary veins (HP:0011718)1.71378291
134Congenital, generalized hypertrichosis (HP:0004540)1.70778822
135Redundant skin (HP:0001582)1.70775875
136Meckel diverticulum (HP:0002245)1.70252280
137Duplication of thumb phalanx (HP:0009942)1.69045887
138Disproportionate short-trunk short stature (HP:0003521)1.68812046
139Abnormal delivery (HP:0001787)1.68748485
140Postaxial foot polydactyly (HP:0001830)1.67871645
141Nasolacrimal duct obstruction (HP:0000579)1.67663669
142Aplasia/Hypoplasia of the middle phalanges of the hand (HP:0009843)1.67196191
143Capillary hemangiomas (HP:0005306)1.66871699
144Aplastic anemia (HP:0001915)1.66539614
145Periauricular skin pits (HP:0100277)1.66453392
146Preauricular pit (HP:0004467)1.66453392
147Submucous cleft hard palate (HP:0000176)1.66182602
148Long clavicles (HP:0000890)1.65782570
149Deep philtrum (HP:0002002)1.65219317
150Anal stenosis (HP:0002025)1.64813130
151Chronic hepatic failure (HP:0100626)1.64445095
152Fused cervical vertebrae (HP:0002949)1.63922308
153Aplasia/Hypoplasia of the 5th finger (HP:0006262)1.63300974
154Aortic valve stenosis (HP:0001650)1.63233285
155Triphalangeal thumb (HP:0001199)1.61592221
156Birth length less than 3rd percentile (HP:0003561)1.60726736
157Deformed tarsal bones (HP:0008119)1.59662153
158Elfin facies (HP:0004428)1.57783394
159Abnormality of the phalanges of the 2nd finger (HP:0009541)1.56796854
160Increased nuchal translucency (HP:0010880)1.55884067
161Ulnar bowing (HP:0003031)1.55694529
162Bladder diverticulum (HP:0000015)1.50849885
163Irregular epiphyses (HP:0010582)1.49108999
164Anophthalmia (HP:0000528)1.48470945
165Omphalocele (HP:0001539)1.48240463

Predicted kinase interactions (KEA)

RankGene SetZ-score
1INSRR4.17432038
2MKNK23.58664337
3MKNK13.55625126
4CDK83.05307167
5ZAK2.65700251
6NUAK12.57067631
7MYLK2.53442153
8PBK2.45587471
9SRPK12.34568988
10AKT32.32396672
11LATS12.27810134
12CASK2.24908727
13BRSK22.19819401
14EIF2AK32.12584822
15EIF2AK12.04300480
16ERBB32.01910442
17TTK2.00815482
18CLK11.99180036
19PNCK1.95400637
20TGFBR11.89366359
21FRK1.87661723
22ERBB41.84425692
23YES11.80293655
24PLK41.78258841
25PDK21.77388735
26NME21.77015897
27TLK11.76935362
28NEK11.74785942
29TAF11.56925269
30WEE11.53823200
31PASK1.40482668
32PKN21.40351053
33EIF2AK21.38931313
34CDC71.37959897
35NLK1.33366206
36TNIK1.28274193
37TIE11.27391004
38BMPR1B1.27182048
39TAOK21.25063228
40FLT31.24905382
41BRD41.24890069
42PTK2B1.24049336
43PLK31.23904574
44PLK21.23476005
45MAP2K31.23172861
46DMPK1.20711593
47OBSCN1.19293137
48MAPK131.17543707
49TSSK61.17489182
50LATS21.16932224
51VRK11.15618176
52STK161.15356831
53EPHA31.14649867
54FGFR11.14418289
55IRAK41.13522758
56PRPF4B1.12122436
57CCNB11.10465581
58BMPR21.08101058
59NEK91.03377384
60ACVR1B1.00605638
61PDGFRA0.98795902
62STK100.98273848
63CDK70.98207485
64PIK3CA0.97814578
65TXK0.92426328
66TGFBR20.89377346
67NEK20.86499394
68TRIM280.86277781
69STK38L0.83394377
70EPHB20.81365382
71TEC0.81092605
72BUB10.80462142
73SIK30.79297452
74MAP2K60.77706615
75MUSK0.77273050
76BRSK10.76147884
77STK240.75972815
78MAP3K140.74211590
79PRKD20.70265304
80VRK20.69671659
81BTK0.69620916
82ATR0.68835242
83SGK20.67328007
84CHEK10.66934504
85KDR0.66175509
86PAK20.65935107
87CSNK2A10.65910944
88PIK3CG0.64277067
89PLK10.64062399
90CSF1R0.63816349
91TTN0.63378842
92MAP2K70.62387845
93CDK120.62147708
94CDK30.61383378
95ADRBK10.61234880
96AURKB0.61095423
97PRKCE0.60247591
98CSNK1G10.59722920
99MST40.58193626
100MET0.57914334
101CAMK1G0.57158356
102KIT0.56680187
103MAP3K100.56478043
104MAP3K60.56222312
105NEK60.56216698
106ILK0.55884224
107STK30.55775790
108RPS6KA60.55236665
109RPS6KA40.54490134
110PIM20.54113051
111STK40.53844308
112RPS6KB20.52606901
113EEF2K0.52389882
114MAP4K20.52376241
115CDK60.50896592
116PRKG20.50790089
117FER0.50758519
118MELK0.49834639
119PIM10.49792886
120MAP3K80.49563545
121MARK30.48345444
122AURKA0.47327143
123DYRK30.46337024
124ZAP700.43966996
125PTK20.43335634
126CHUK0.41967848
127PAK40.40967499
128FGFR20.38964090
129ATM0.38641347
130SCYL20.38348335
131RPS6KC10.37149997
132RPS6KL10.37149997
133MAP3K120.36920598
134CDK10.36791248
135RPS6KA50.36451837
136BCR0.35820733
137WNK30.35167330
138CDK20.35101572
139JAK30.34851592
140CHEK20.34776172
141ADRBK20.34424857
142LIMK10.34335589
143CSNK1A1L0.33738188
144CDK90.33410680
145PDGFRB0.33040411
146ROCK10.32469001
147LRRK20.32457728
148NTRK10.31420476
149RPS6KB10.31028186
150PRKDC0.28812634
151ROCK20.26177855

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.38457764
2Base excision repair_Homo sapiens_hsa034103.30658844
3Mismatch repair_Homo sapiens_hsa034303.09911212
4Protein export_Homo sapiens_hsa030603.01083564
5Homologous recombination_Homo sapiens_hsa034402.80145002
6Ribosome_Homo sapiens_hsa030102.78269378
7Basal transcription factors_Homo sapiens_hsa030222.66849131
8RNA polymerase_Homo sapiens_hsa030202.43873938
9Cell cycle_Homo sapiens_hsa041102.37329401
10Spliceosome_Homo sapiens_hsa030402.34869287
11Nucleotide excision repair_Homo sapiens_hsa034202.32122797
12Non-homologous end-joining_Homo sapiens_hsa034502.31573720
13Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.09453840
14Basal cell carcinoma_Homo sapiens_hsa052171.91620047
15Pyrimidine metabolism_Homo sapiens_hsa002401.91289001
16Proteasome_Homo sapiens_hsa030501.87330628
17Fanconi anemia pathway_Homo sapiens_hsa034601.85976164
18* RNA degradation_Homo sapiens_hsa030181.78016186
19Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.74584997
20* RNA transport_Homo sapiens_hsa030131.61849787
21Pyruvate metabolism_Homo sapiens_hsa006201.58549485
22Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.57753174
23Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.46109396
24Protein digestion and absorption_Homo sapiens_hsa049741.44023290
25Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.41124592
26Selenocompound metabolism_Homo sapiens_hsa004501.39587556
27Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.39010903
28Purine metabolism_Homo sapiens_hsa002301.38945702
29N-Glycan biosynthesis_Homo sapiens_hsa005101.37864679
30TGF-beta signaling pathway_Homo sapiens_hsa043501.35942623
31Hippo signaling pathway_Homo sapiens_hsa043901.34919154
32Thyroid cancer_Homo sapiens_hsa052161.33902736
33SNARE interactions in vesicular transport_Homo sapiens_hsa041301.31704497
34Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.31682433
35Adherens junction_Homo sapiens_hsa045201.31452092
362-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.29877633
37Transcriptional misregulation in cancer_Homo sapiens_hsa052021.23950264
38Cysteine and methionine metabolism_Homo sapiens_hsa002701.23481776
39* mRNA surveillance pathway_Homo sapiens_hsa030151.22167148
40Arachidonic acid metabolism_Homo sapiens_hsa005901.20569435
41Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.17335222
42Herpes simplex infection_Homo sapiens_hsa051681.15257043
43Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.14880786
44One carbon pool by folate_Homo sapiens_hsa006701.14067672
45Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.09678783
46p53 signaling pathway_Homo sapiens_hsa041151.07350138
47Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.06118284
48Sulfur metabolism_Homo sapiens_hsa009201.04525677
49Hedgehog signaling pathway_Homo sapiens_hsa043401.03045193
50Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.03005625
51Propanoate metabolism_Homo sapiens_hsa006401.02378942
52Wnt signaling pathway_Homo sapiens_hsa043101.00708901
53Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.98307126
54Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.93293940
55Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.92717384
56Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.92669932
57Biosynthesis of amino acids_Homo sapiens_hsa012300.89166200
58Pathways in cancer_Homo sapiens_hsa052000.88829017
59Small cell lung cancer_Homo sapiens_hsa052220.87446469
60Lysine degradation_Homo sapiens_hsa003100.87369047
61Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.86924679
62HTLV-I infection_Homo sapiens_hsa051660.86580076
63Steroid biosynthesis_Homo sapiens_hsa001000.83255549
64Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.82863891
65Sulfur relay system_Homo sapiens_hsa041220.82252910
66MicroRNAs in cancer_Homo sapiens_hsa052060.81552655
67Epstein-Barr virus infection_Homo sapiens_hsa051690.80365379
68Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.80358996
69Measles_Homo sapiens_hsa051620.79881112
70Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.79260944
71NF-kappa B signaling pathway_Homo sapiens_hsa040640.76764598
72Glutathione metabolism_Homo sapiens_hsa004800.75956761
73Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.75869455
74Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.74636702
75Oxidative phosphorylation_Homo sapiens_hsa001900.74210906
76Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.73553836
77Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.73419460
78Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.72782050
79Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.72602336
80Legionellosis_Homo sapiens_hsa051340.72381256
81Central carbon metabolism in cancer_Homo sapiens_hsa052300.71316888
82Focal adhesion_Homo sapiens_hsa045100.70804070
83PI3K-Akt signaling pathway_Homo sapiens_hsa041510.69836479
84Malaria_Homo sapiens_hsa051440.68493221
85Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.68364733
86Prostate cancer_Homo sapiens_hsa052150.68295430
87RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.65323860
88Notch signaling pathway_Homo sapiens_hsa043300.61043796
89Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.60848400
90Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.60523231
91Huntingtons disease_Homo sapiens_hsa050160.60497480
92Alcoholism_Homo sapiens_hsa050340.58161608
93Leishmaniasis_Homo sapiens_hsa051400.56770484
94Carbon metabolism_Homo sapiens_hsa012000.56435903
95ECM-receptor interaction_Homo sapiens_hsa045120.55561924
96Proteoglycans in cancer_Homo sapiens_hsa052050.55216960
97Parkinsons disease_Homo sapiens_hsa050120.54195447
98Jak-STAT signaling pathway_Homo sapiens_hsa046300.53874169
99Alzheimers disease_Homo sapiens_hsa050100.53352968
100Platelet activation_Homo sapiens_hsa046110.52094804
101NOD-like receptor signaling pathway_Homo sapiens_hsa046210.49752594
102Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.49715542
103Melanoma_Homo sapiens_hsa052180.49498203
104Shigellosis_Homo sapiens_hsa051310.49258711
105Leukocyte transendothelial migration_Homo sapiens_hsa046700.49250583
106Galactose metabolism_Homo sapiens_hsa000520.48827122
107Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.48254268
108Colorectal cancer_Homo sapiens_hsa052100.48070471
109Melanogenesis_Homo sapiens_hsa049160.46595831
110AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.46223896
111Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.45883764
112Hepatitis B_Homo sapiens_hsa051610.45686193
113Endometrial cancer_Homo sapiens_hsa052130.45052892
114Fatty acid elongation_Homo sapiens_hsa000620.44747774
115Dilated cardiomyopathy_Homo sapiens_hsa054140.44688812
116Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.42894606
117Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.42517282
118Antigen processing and presentation_Homo sapiens_hsa046120.42239108
119Circadian rhythm_Homo sapiens_hsa047100.40927493
120Rap1 signaling pathway_Homo sapiens_hsa040150.39529964
121Metabolic pathways_Homo sapiens_hsa011000.38117879
122Oocyte meiosis_Homo sapiens_hsa041140.35621739
123Intestinal immune network for IgA production_Homo sapiens_hsa046720.35402950
124Arginine and proline metabolism_Homo sapiens_hsa003300.34979522
125Tight junction_Homo sapiens_hsa045300.34670574
126Cardiac muscle contraction_Homo sapiens_hsa042600.34126299
127Vitamin digestion and absorption_Homo sapiens_hsa049770.34009574
128Influenza A_Homo sapiens_hsa051640.33858388
129Hematopoietic cell lineage_Homo sapiens_hsa046400.33669425
130Viral carcinogenesis_Homo sapiens_hsa052030.32649207
131TNF signaling pathway_Homo sapiens_hsa046680.31764921
132Amoebiasis_Homo sapiens_hsa051460.31166905
133Regulation of actin cytoskeleton_Homo sapiens_hsa048100.31054937
134Systemic lupus erythematosus_Homo sapiens_hsa053220.30911385
135Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.30891475
136Autoimmune thyroid disease_Homo sapiens_hsa053200.28929354
137Folate biosynthesis_Homo sapiens_hsa007900.28798152
138Axon guidance_Homo sapiens_hsa043600.28684678
139cGMP-PKG signaling pathway_Homo sapiens_hsa040220.28606089
140Toll-like receptor signaling pathway_Homo sapiens_hsa046200.28194140
141Primary immunodeficiency_Homo sapiens_hsa053400.28005996

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