Rank | Gene Set | Z-score |
---|---|---|
1 | axon ensheathment in central nervous system (GO:0032291) | 5.80027500 |
2 | central nervous system myelination (GO:0022010) | 5.80027500 |
3 | synaptic vesicle maturation (GO:0016188) | 5.08207281 |
4 | locomotory exploration behavior (GO:0035641) | 4.24037588 |
5 | glycine transport (GO:0015816) | 4.09375633 |
6 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 3.99478454 |
7 | L-amino acid import (GO:0043092) | 3.98942862 |
8 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 3.81752108 |
9 | layer formation in cerebral cortex (GO:0021819) | 3.81069047 |
10 | positive regulation of synapse maturation (GO:0090129) | 3.73111709 |
11 | ensheathment of neurons (GO:0007272) | 3.72476843 |
12 | axon ensheathment (GO:0008366) | 3.72476843 |
13 | myelination (GO:0042552) | 3.69571426 |
14 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 3.61843091 |
15 | dendritic spine morphogenesis (GO:0060997) | 3.57931540 |
16 | establishment of mitochondrion localization (GO:0051654) | 3.55286054 |
17 | regulation of synaptic vesicle exocytosis (GO:2000300) | 3.51236037 |
18 | sodium ion export (GO:0071436) | 3.45695256 |
19 | dendrite morphogenesis (GO:0048813) | 3.45271802 |
20 | postsynaptic membrane organization (GO:0001941) | 3.42348844 |
21 | regulation of synapse structural plasticity (GO:0051823) | 3.40845350 |
22 | nerve growth factor signaling pathway (GO:0038180) | 3.39607277 |
23 | myelin maintenance (GO:0043217) | 3.29566175 |
24 | cellular potassium ion homeostasis (GO:0030007) | 3.28324302 |
25 | synaptic vesicle exocytosis (GO:0016079) | 3.22849286 |
26 | vocalization behavior (GO:0071625) | 3.22798203 |
27 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 3.22567722 |
28 | neuronal action potential propagation (GO:0019227) | 3.20777330 |
29 | regulation of neuronal synaptic plasticity (GO:0048168) | 3.19371051 |
30 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 3.18770642 |
31 | regulation of synapse maturation (GO:0090128) | 3.18229668 |
32 | glutamate secretion (GO:0014047) | 3.18098567 |
33 | adult walking behavior (GO:0007628) | 3.10054038 |
34 | amino acid import (GO:0043090) | 3.07992463 |
35 | gamma-aminobutyric acid transport (GO:0015812) | 3.07858176 |
36 | neuromuscular process controlling balance (GO:0050885) | 3.07603140 |
37 | neuronal ion channel clustering (GO:0045161) | 3.06386902 |
38 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.03901087 |
39 | regulation of ARF protein signal transduction (GO:0032012) | 3.01664346 |
40 | potassium ion import (GO:0010107) | 3.01629772 |
41 | regulation of synaptic vesicle transport (GO:1902803) | 3.01184437 |
42 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 3.00993242 |
43 | cell communication by electrical coupling (GO:0010644) | 2.98169059 |
44 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 2.96895064 |
45 | long-chain fatty acid biosynthetic process (GO:0042759) | 2.94867137 |
46 | response to methylmercury (GO:0051597) | 2.93671304 |
47 | exploration behavior (GO:0035640) | 2.93421841 |
48 | peptidyl-tyrosine autophosphorylation (GO:0038083) | 2.90142549 |
49 | axonal fasciculation (GO:0007413) | 2.88329010 |
50 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 2.88197557 |
51 | neuron recognition (GO:0008038) | 2.87770678 |
52 | membrane tubulation (GO:0097320) | 2.87460945 |
53 | organelle transport along microtubule (GO:0072384) | 2.86594573 |
54 | regulation of glutamate receptor signaling pathway (GO:1900449) | 2.86494727 |
55 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 2.86377538 |
56 | neuron cell-cell adhesion (GO:0007158) | 2.85760401 |
57 | negative regulation of neurotransmitter transport (GO:0051589) | 2.85551635 |
58 | vesicle transport along microtubule (GO:0047496) | 2.85214751 |
59 | regulation of ARF GTPase activity (GO:0032312) | 2.85200294 |
60 | dendritic spine organization (GO:0097061) | 2.84800299 |
61 | negative regulation of dendrite morphogenesis (GO:0050774) | 2.82775159 |
62 | neurotransmitter secretion (GO:0007269) | 2.79554323 |
63 | cerebellar Purkinje cell layer development (GO:0021680) | 2.79030520 |
64 | myelination in peripheral nervous system (GO:0022011) | 2.77137396 |
65 | peripheral nervous system axon ensheathment (GO:0032292) | 2.77137396 |
66 | response to auditory stimulus (GO:0010996) | 2.76973041 |
67 | auditory behavior (GO:0031223) | 2.76074887 |
68 | protein localization to synapse (GO:0035418) | 2.75441803 |
69 | negative regulation of neurotransmitter secretion (GO:0046929) | 2.74957153 |
70 | negative regulation of axonogenesis (GO:0050771) | 2.72903027 |
71 | semaphorin-plexin signaling pathway (GO:0071526) | 2.72499106 |
72 | clathrin coat assembly (GO:0048268) | 2.71811548 |
73 | establishment of mitochondrion localization, microtubule-mediated (GO:0034643) | 2.71625673 |
74 | mitochondrion transport along microtubule (GO:0047497) | 2.71625673 |
75 | protein localization to endosome (GO:0036010) | 2.71586088 |
76 | potassium ion homeostasis (GO:0055075) | 2.71525902 |
77 | establishment of nucleus localization (GO:0040023) | 2.70565437 |
78 | activation of protein kinase A activity (GO:0034199) | 2.70035577 |
79 | transmission of nerve impulse (GO:0019226) | 2.68810785 |
80 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 2.68261579 |
81 | cell-cell junction maintenance (GO:0045217) | 2.67358954 |
82 | cerebellar Purkinje cell differentiation (GO:0021702) | 2.66584244 |
83 | mating behavior (GO:0007617) | 2.65980437 |
84 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 2.65777431 |
85 | axon cargo transport (GO:0008088) | 2.64916359 |
86 | neuromuscular process controlling posture (GO:0050884) | 2.64587420 |
87 | synaptic transmission, glutamatergic (GO:0035249) | 2.63629120 |
88 | regulation of synaptic plasticity (GO:0048167) | 2.63599549 |
89 | cellular response to catecholamine stimulus (GO:0071870) | 2.61186080 |
90 | cellular response to monoamine stimulus (GO:0071868) | 2.61186080 |
91 | dopamine receptor signaling pathway (GO:0007212) | 2.60666792 |
92 | positive regulation of dendritic spine development (GO:0060999) | 2.59938850 |
93 | cell migration in hindbrain (GO:0021535) | 2.56629686 |
94 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 2.55136333 |
95 | cellular response to nerve growth factor stimulus (GO:1990090) | 2.54559897 |
96 | response to nerve growth factor (GO:1990089) | 2.54559897 |
97 | long-term memory (GO:0007616) | 2.53551865 |
98 | regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 2.52116858 |
99 | positive regulation of dendrite development (GO:1900006) | 2.52063295 |
100 | cerebellar granule cell differentiation (GO:0021707) | 2.51834317 |
101 | synaptic vesicle endocytosis (GO:0048488) | 2.50383832 |
102 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 2.50307221 |
103 | prepulse inhibition (GO:0060134) | 2.48668161 |
104 | negative regulation of protein localization to cell surface (GO:2000009) | 2.47591578 |
105 | membrane depolarization during action potential (GO:0086010) | 2.47421580 |
106 | negative regulation of microtubule polymerization (GO:0031115) | 2.47103872 |
107 | neurotransmitter transport (GO:0006836) | 2.46133063 |
108 | neuromuscular process (GO:0050905) | 2.44490970 |
109 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.44468524 |
110 | detection of temperature stimulus involved in sensory perception (GO:0050961) | 2.42629237 |
111 | detection of temperature stimulus involved in sensory perception of pain (GO:0050965) | 2.42629237 |
112 | regulation of voltage-gated calcium channel activity (GO:1901385) | 2.42236848 |
113 | proline transport (GO:0015824) | 2.41160590 |
114 | negative regulation of cell size (GO:0045792) | 2.40891904 |
115 | positive regulation of potassium ion transport (GO:0043268) | 2.40037637 |
116 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800) | 2.39953195 |
117 | regulation of neurotransmitter levels (GO:0001505) | 2.39443613 |
118 | glutamate receptor signaling pathway (GO:0007215) | 2.39379893 |
119 | regulation of neurotransmitter secretion (GO:0046928) | 2.39224184 |
120 | cerebral cortex radially oriented cell migration (GO:0021799) | 2.38491388 |
121 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 2.37283067 |
122 | regulation of dendritic spine morphogenesis (GO:0061001) | 2.37006550 |
123 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 2.36721716 |
124 | presynaptic membrane organization (GO:0097090) | 2.36414658 |
125 | positive regulation of membrane potential (GO:0045838) | 2.36169931 |
126 | negative regulation of catenin import into nucleus (GO:0035414) | 2.36047213 |
127 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 2.35920149 |
128 | neuron-neuron synaptic transmission (GO:0007270) | 2.35744950 |
129 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 2.34383093 |
130 | axon extension (GO:0048675) | 2.33681264 |
131 | regulation of postsynaptic membrane potential (GO:0060078) | 2.28474816 |
132 | regulation of dendrite morphogenesis (GO:0048814) | 2.27255197 |
133 | sarcoplasmic reticulum calcium ion transport (GO:0070296) | 2.27229518 |
134 | cell communication involved in cardiac conduction (GO:0086065) | 2.26348939 |
135 | neuromuscular synaptic transmission (GO:0007274) | 2.26347017 |
136 | response to monoamine (GO:0071867) | 2.24605754 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.87179377 |
2 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.60799502 |
3 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.38047519 |
4 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.32141335 |
5 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.26172869 |
6 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.26172869 |
7 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.20202578 |
8 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.20162741 |
9 | * LXR_22292898_ChIP-Seq_THP-1_Human | 2.20162696 |
10 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.18009133 |
11 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.17722067 |
12 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.14494393 |
13 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.14375171 |
14 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.96961249 |
15 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.94776768 |
16 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.93366038 |
17 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.92350959 |
18 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.90342991 |
19 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.88827161 |
20 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.87026623 |
21 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.84932500 |
22 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.84616842 |
23 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.83327195 |
24 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.82829041 |
25 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.79656042 |
26 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.73632595 |
27 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.73238227 |
28 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.67952320 |
29 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.62240352 |
30 | * KDM2B_26808549_Chip-Seq_K562_Human | 1.59593500 |
31 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.58896823 |
32 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.54041507 |
33 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.50822413 |
34 | * WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.50267632 |
35 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.48364648 |
36 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.48204114 |
37 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.43421315 |
38 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.41970179 |
39 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.39320330 |
40 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.38647081 |
41 | * KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.38052945 |
42 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.35999105 |
43 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.35933358 |
44 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.33794599 |
45 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.32893366 |
46 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.32160387 |
47 | * TCF7_22412390_ChIP-Seq_EML_Mouse | 1.28880519 |
48 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.27206257 |
49 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.25572746 |
50 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.25506343 |
51 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.24983581 |
52 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.23016540 |
53 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.22797027 |
54 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.22510998 |
55 | P68_20966046_ChIP-Seq_HELA_Human | 1.22197931 |
56 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.21469220 |
57 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.19034838 |
58 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.18735259 |
59 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.18501597 |
60 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.18307780 |
61 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.17049021 |
62 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.16507609 |
63 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.16185705 |
64 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.16150433 |
65 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.15077297 |
66 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.14680178 |
67 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.13995511 |
68 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.13260118 |
69 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.13054993 |
70 | TP53_23651856_ChIP-Seq_MEFs_Mouse | 1.12044879 |
71 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.11947712 |
72 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.11816857 |
73 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.11740391 |
74 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.11617556 |
75 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.11196447 |
76 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.10729106 |
77 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.09989774 |
78 | * KDM2B_26808549_Chip-Seq_DND41_Human | 1.09833378 |
79 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.09645462 |
80 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.09523754 |
81 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.09436102 |
82 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.08904600 |
83 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.08831069 |
84 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.08459799 |
85 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.08209528 |
86 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.07723506 |
87 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.07193564 |
88 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.06345609 |
89 | STAT3_23295773_ChIP-Seq_U87_Human | 1.06321140 |
90 | OCT4_19829295_ChIP-Seq_ESCs_Human | 1.06301089 |
91 | * AR_19668381_ChIP-Seq_PC3_Human | 1.03569136 |
92 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.03412327 |
93 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.03152385 |
94 | * SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.02430043 |
95 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.02057829 |
96 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.01804240 |
97 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.01766488 |
98 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.01734942 |
99 | * KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.01427811 |
100 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.01288528 |
101 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.00280170 |
102 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 0.99782867 |
103 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.97813353 |
104 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.97684811 |
105 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 0.97448441 |
106 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 0.97448441 |
107 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 0.97100095 |
108 | MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 0.95393712 |
109 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 0.94552075 |
110 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 0.94266416 |
111 | TP63_22573176_ChIP-Seq_HFKS_Human | 0.93763678 |
112 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.93762508 |
113 | * CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.93342214 |
114 | * KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.92758950 |
115 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 0.92742167 |
116 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.92463120 |
117 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.92144948 |
118 | TP53_16413492_ChIP-PET_HCT116_Human | 0.91573366 |
119 | * RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 0.90850518 |
120 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.90747505 |
121 | TCF4_23295773_ChIP-Seq_U87_Human | 0.90420824 |
122 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.89710443 |
123 | KLF4_19829295_ChIP-Seq_ESCs_Human | 0.89303889 |
124 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 0.89294737 |
125 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.88984472 |
126 | GATA1_19941826_ChIP-Seq_K562_Human | 0.88123214 |
127 | * GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.87451727 |
128 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.86849500 |
129 | TFAP2A_17053090_ChIP-ChIP_MCF-7_Human | 0.86536345 |
130 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.86390596 |
131 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.85789621 |
132 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.85291934 |
133 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.83307440 |
134 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.82262170 |
135 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.82066026 |
136 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 0.80209739 |
137 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.79043513 |
138 | RXR_22108803_ChIP-Seq_LS180_Human | 0.78710962 |
139 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 0.77750110 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 5.18637191 |
2 | MP0004270_analgesia | 3.63647133 |
3 | MP0000920_abnormal_myelination | 3.33063890 |
4 | MP0003880_abnormal_central_pattern | 3.31906909 |
5 | MP0003635_abnormal_synaptic_transmissio | 3.21543150 |
6 | MP0005423_abnormal_somatic_nervous | 3.19691163 |
7 | MP0002064_seizures | 2.68337573 |
8 | MP0003329_amyloid_beta_deposits | 2.64527625 |
9 | MP0009046_muscle_twitch | 2.60425292 |
10 | MP0004885_abnormal_endolymph | 2.52755704 |
11 | MP0003690_abnormal_glial_cell | 2.51252587 |
12 | MP0001486_abnormal_startle_reflex | 2.47498673 |
13 | MP0002063_abnormal_learning/memory/cond | 2.45838643 |
14 | MP0009745_abnormal_behavioral_response | 2.41819799 |
15 | MP0002272_abnormal_nervous_system | 2.41057419 |
16 | MP0003705_abnormal_hypodermis_morpholog | 2.35178497 |
17 | MP0002734_abnormal_mechanical_nocicepti | 2.28837808 |
18 | MP0000778_abnormal_nervous_system | 2.20976055 |
19 | MP0008569_lethality_at_weaning | 2.06644670 |
20 | MP0003634_abnormal_glial_cell | 2.04193367 |
21 | MP0002572_abnormal_emotion/affect_behav | 1.98894925 |
22 | MP0001968_abnormal_touch/_nociception | 1.98467703 |
23 | MP0004858_abnormal_nervous_system | 1.96796716 |
24 | MP0005623_abnormal_meninges_morphology | 1.83386366 |
25 | MP0002822_catalepsy | 1.80689676 |
26 | MP0000955_abnormal_spinal_cord | 1.79548219 |
27 | MP0002733_abnormal_thermal_nociception | 1.77395085 |
28 | MP0009780_abnormal_chondrocyte_physiolo | 1.77337758 |
29 | MP0001970_abnormal_pain_threshold | 1.75574234 |
30 | MP0003633_abnormal_nervous_system | 1.74512640 |
31 | MP0004742_abnormal_vestibular_system | 1.73076518 |
32 | MP0004811_abnormal_neuron_physiology | 1.71211410 |
33 | MP0002249_abnormal_larynx_morphology | 1.69481204 |
34 | MP0000569_abnormal_digit_pigmentation | 1.68441914 |
35 | MP0002067_abnormal_sensory_capabilities | 1.59841770 |
36 | MP0005410_abnormal_fertilization | 1.59074807 |
37 | MP0003631_nervous_system_phenotype | 1.57213633 |
38 | MP0001440_abnormal_grooming_behavior | 1.55180412 |
39 | MP0002882_abnormal_neuron_morphology | 1.53308967 |
40 | MP0001299_abnormal_eye_distance/ | 1.51745865 |
41 | MP0000604_amyloidosis | 1.51735430 |
42 | MP0003172_abnormal_lysosome_physiology | 1.50687320 |
43 | MP0003632_abnormal_nervous_system | 1.45468731 |
44 | MP0002066_abnormal_motor_capabilities/c | 1.44365750 |
45 | MP0000751_myopathy | 1.43252252 |
46 | MP0002184_abnormal_innervation | 1.43125681 |
47 | MP0004924_abnormal_behavior | 1.42144894 |
48 | MP0005386_behavior/neurological_phenoty | 1.42144894 |
49 | MP0002229_neurodegeneration | 1.40988794 |
50 | MP0002735_abnormal_chemical_nociception | 1.35117311 |
51 | MP0000747_muscle_weakness | 1.35024730 |
52 | MP0002736_abnormal_nociception_after | 1.33428847 |
53 | MP0004145_abnormal_muscle_electrophysio | 1.30900674 |
54 | MP0004142_abnormal_muscle_tone | 1.29328934 |
55 | MP0002557_abnormal_social/conspecific_i | 1.26368388 |
56 | MP0001501_abnormal_sleep_pattern | 1.26038692 |
57 | MP0000566_synostosis | 1.23771524 |
58 | MP0005670_abnormal_white_adipose | 1.23696508 |
59 | MP0004036_abnormal_muscle_relaxation | 1.20754858 |
60 | MP0001348_abnormal_lacrimal_gland | 1.16399168 |
61 | MP0001958_emphysema | 1.16165100 |
62 | MP0005171_absent_coat_pigmentation | 1.16147815 |
63 | MP0002152_abnormal_brain_morphology | 1.15252462 |
64 | MP0003123_paternal_imprinting | 1.13934709 |
65 | MP0002909_abnormal_adrenal_gland | 1.13624313 |
66 | MP0003279_aneurysm | 1.05297399 |
67 | MP0001177_atelectasis | 1.05108409 |
68 | MP0001485_abnormal_pinna_reflex | 1.04937845 |
69 | MP0003950_abnormal_plasma_membrane | 1.04527586 |
70 | MP0002089_abnormal_postnatal_growth/wei | 1.03852282 |
71 | MP0005645_abnormal_hypothalamus_physiol | 1.03622453 |
72 | MP0003646_muscle_fatigue | 1.02252562 |
73 | MP0003075_altered_response_to | 1.01923025 |
74 | MP0001849_ear_inflammation | 0.99452483 |
75 | MP0003283_abnormal_digestive_organ | 0.99057041 |
76 | MP0003122_maternal_imprinting | 0.98334095 |
77 | MP0001905_abnormal_dopamine_level | 0.97534720 |
78 | MP0000579_abnormal_nail_morphology | 0.96101308 |
79 | MP0000003_abnormal_adipose_tissue | 0.94996754 |
80 | MP0004134_abnormal_chest_morphology | 0.93875586 |
81 | MP0006138_congestive_heart_failure | 0.92283652 |
82 | MP0001502_abnormal_circadian_rhythm | 0.91400525 |
83 | MP0003879_abnormal_hair_cell | 0.90069820 |
84 | MP0005058_abnormal_lysosome_morphology | 0.88974176 |
85 | MP0002106_abnormal_muscle_physiology | 0.87147311 |
86 | MP0002108_abnormal_muscle_morphology | 0.85367439 |
87 | MP0010368_abnormal_lymphatic_system | 0.84286676 |
88 | MP0005167_abnormal_blood-brain_barrier | 0.84109387 |
89 | MP0006276_abnormal_autonomic_nervous | 0.84079318 |
90 | MP0000733_abnormal_muscle_development | 0.83741977 |
91 | MP0005369_muscle_phenotype | 0.83308218 |
92 | MP0003045_fibrosis | 0.82900520 |
93 | MP0005409_darkened_coat_color | 0.82403586 |
94 | MP0000534_abnormal_ureter_morphology | 0.82368795 |
95 | MP0002752_abnormal_somatic_nervous | 0.82337174 |
96 | MP0005375_adipose_tissue_phenotype | 0.82158249 |
97 | MP0000462_abnormal_digestive_system | 0.82133276 |
98 | MP0008438_abnormal_cutaneous_collagen | 0.81643065 |
99 | MP0001529_abnormal_vocalization | 0.81431393 |
100 | MP0002090_abnormal_vision | 0.81003577 |
101 | MP0005666_abnormal_adipose_tissue | 0.80128357 |
102 | MP0005620_abnormal_muscle_contractility | 0.77140991 |
103 | MP0004084_abnormal_cardiac_muscle | 0.76731003 |
104 | MP0003137_abnormal_impulse_conducting | 0.73725834 |
105 | MP0004510_myositis | 0.73678620 |
106 | MP0008961_abnormal_basal_metabolism | 0.72911090 |
107 | MP0005451_abnormal_body_composition | 0.72442827 |
108 | MP0005646_abnormal_pituitary_gland | 0.72405333 |
109 | MP0004233_abnormal_muscle_weight | 0.71890695 |
110 | MP0002269_muscular_atrophy | 0.71362373 |
111 | MP0001963_abnormal_hearing_physiology | 0.71176314 |
112 | MP0000013_abnormal_adipose_tissue | 0.70957971 |
113 | MP0005595_abnormal_vascular_smooth | 0.70925632 |
114 | MP0005551_abnormal_eye_electrophysiolog | 0.70900976 |
115 | MP0003303_peritoneal_inflammation | 0.68120699 |
116 | MP0003861_abnormal_nervous_system | 0.67487568 |
117 | MP0010678_abnormal_skin_adnexa | 0.67255008 |
118 | MP0008874_decreased_physiological_sensi | 0.67135946 |
119 | MP0003787_abnormal_imprinting | 0.66970109 |
120 | MP0000749_muscle_degeneration | 0.65505509 |
121 | MP0001984_abnormal_olfaction | 0.65156140 |
122 | MP0004043_abnormal_pH_regulation | 0.65000853 |
123 | MP0004130_abnormal_muscle_cell | 0.64966699 |
124 | MP0004087_abnormal_muscle_fiber | 0.64106937 |
125 | MP0002069_abnormal_eating/drinking_beha | 0.63583510 |
126 | MP0004085_abnormal_heartbeat | 0.62078671 |
127 | MP0001943_abnormal_respiration | 0.59972806 |
128 | MP0000759_abnormal_skeletal_muscle | 0.58750950 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Supranuclear gaze palsy (HP:0000605) | 5.07583171 |
2 | Myokymia (HP:0002411) | 4.49381242 |
3 | Neurofibrillary tangles (HP:0002185) | 4.46669089 |
4 | Termporal pattern (HP:0011008) | 4.26295309 |
5 | Insidious onset (HP:0003587) | 4.26295309 |
6 | Ankle clonus (HP:0011448) | 4.24517867 |
7 | Action tremor (HP:0002345) | 4.11828221 |
8 | Abnormality of the corticospinal tract (HP:0002492) | 4.00478742 |
9 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 3.88986647 |
10 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 3.88986647 |
11 | Cerebral inclusion bodies (HP:0100314) | 3.71902280 |
12 | Onion bulb formation (HP:0003383) | 3.57399481 |
13 | Peripheral hypomyelination (HP:0007182) | 3.50956758 |
14 | Spastic gait (HP:0002064) | 3.31831781 |
15 | Cerebral aneurysm (HP:0004944) | 3.19580432 |
16 | Focal seizures (HP:0007359) | 3.16039245 |
17 | Urinary urgency (HP:0000012) | 3.06393134 |
18 | Type 1 muscle fiber predominance (HP:0003803) | 3.05069640 |
19 | Urinary bladder sphincter dysfunction (HP:0002839) | 3.02606521 |
20 | Focal motor seizures (HP:0011153) | 3.02438106 |
21 | Intention tremor (HP:0002080) | 3.01926858 |
22 | Dysmetria (HP:0001310) | 2.93268889 |
23 | Lower limb muscle weakness (HP:0007340) | 2.86441604 |
24 | Mutism (HP:0002300) | 2.85019374 |
25 | Segmental peripheral demyelination/remyelination (HP:0003481) | 2.84895765 |
26 | Insomnia (HP:0100785) | 2.82985457 |
27 | Exercise-induced myalgia (HP:0003738) | 2.77148391 |
28 | Akinesia (HP:0002304) | 2.63483218 |
29 | Hammertoe (HP:0001765) | 2.59796526 |
30 | Postural instability (HP:0002172) | 2.58364507 |
31 | Visual hallucinations (HP:0002367) | 2.57177641 |
32 | Muscle fiber splitting (HP:0003555) | 2.56119146 |
33 | Megalencephaly (HP:0001355) | 2.52945804 |
34 | Overriding aorta (HP:0002623) | 2.49344004 |
35 | Progressive cerebellar ataxia (HP:0002073) | 2.47581906 |
36 | Febrile seizures (HP:0002373) | 2.46690216 |
37 | Round ear (HP:0100830) | 2.45890253 |
38 | Difficulty running (HP:0009046) | 2.43668143 |
39 | Neuronal loss in central nervous system (HP:0002529) | 2.43638788 |
40 | Increased variability in muscle fiber diameter (HP:0003557) | 2.40798606 |
41 | Foot dorsiflexor weakness (HP:0009027) | 2.39145599 |
42 | Muscle fiber inclusion bodies (HP:0100299) | 2.38742030 |
43 | Slow saccadic eye movements (HP:0000514) | 2.36081575 |
44 | Stridor (HP:0010307) | 2.35951275 |
45 | Lower limb amyotrophy (HP:0007210) | 2.32761159 |
46 | Clonus (HP:0002169) | 2.32227387 |
47 | Bundle branch block (HP:0011710) | 2.31293014 |
48 | Lymphangioma (HP:0100764) | 2.30933725 |
49 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.30725578 |
50 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 2.30209587 |
51 | Depression (HP:0000716) | 2.29969670 |
52 | Spastic tetraparesis (HP:0001285) | 2.28875617 |
53 | Ulnar claw (HP:0001178) | 2.28585332 |
54 | Decreased motor nerve conduction velocity (HP:0003431) | 2.26961060 |
55 | Nemaline bodies (HP:0003798) | 2.26774751 |
56 | Torticollis (HP:0000473) | 2.26187351 |
57 | Scanning speech (HP:0002168) | 2.24265322 |
58 | Distal lower limb amyotrophy (HP:0008944) | 2.23818511 |
59 | Myopathic facies (HP:0002058) | 2.23385149 |
60 | Sleep apnea (HP:0010535) | 2.23186969 |
61 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.22561175 |
62 | Annular pancreas (HP:0001734) | 2.22255964 |
63 | Bronchomalacia (HP:0002780) | 2.21751676 |
64 | Distal lower limb muscle weakness (HP:0009053) | 2.21135057 |
65 | Dysdiadochokinesis (HP:0002075) | 2.20476367 |
66 | Abnormality of the foot musculature (HP:0001436) | 2.20464819 |
67 | Broad face (HP:0000283) | 2.17804940 |
68 | Abnormal auditory evoked potentials (HP:0006958) | 2.16062160 |
69 | Fetal akinesia sequence (HP:0001989) | 2.15842127 |
70 | Pheochromocytoma (HP:0002666) | 2.14015835 |
71 | Abnormality of skeletal muscle fiber size (HP:0012084) | 2.12245643 |
72 | Macroorchidism (HP:0000053) | 2.11195741 |
73 | Hyporeflexia of lower limbs (HP:0002600) | 2.09923156 |
74 | Truncal ataxia (HP:0002078) | 2.09594648 |
75 | Apathy (HP:0000741) | 2.09225685 |
76 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 2.08606123 |
77 | Epileptic encephalopathy (HP:0200134) | 2.08319941 |
78 | Upper limb amyotrophy (HP:0009129) | 2.07797090 |
79 | Distal upper limb amyotrophy (HP:0007149) | 2.07797090 |
80 | Broad metatarsal (HP:0001783) | 2.07352460 |
81 | Aplasia involving bones of the extremities (HP:0009825) | 2.07172573 |
82 | Aplasia involving bones of the upper limbs (HP:0009823) | 2.07172573 |
83 | Aplasia of the phalanges of the hand (HP:0009802) | 2.07172573 |
84 | Hyperacusis (HP:0010780) | 2.06478824 |
85 | Turricephaly (HP:0000262) | 2.05867154 |
86 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.05128628 |
87 | Genetic anticipation (HP:0003743) | 2.04554381 |
88 | Protrusio acetabuli (HP:0003179) | 2.04076649 |
89 | Papilledema (HP:0001085) | 2.03737619 |
90 | Increased connective tissue (HP:0009025) | 2.03141128 |
91 | Axonal loss (HP:0003447) | 2.02259650 |
92 | Frequent falls (HP:0002359) | 2.02072748 |
93 | Hemiparesis (HP:0001269) | 2.01460798 |
94 | Rapidly progressive (HP:0003678) | 2.01370238 |
95 | Abnormality of binocular vision (HP:0011514) | 2.00910360 |
96 | Diplopia (HP:0000651) | 2.00910360 |
97 | Poor eye contact (HP:0000817) | 2.00521820 |
98 | Abnormal social behavior (HP:0012433) | 1.98257538 |
99 | Impaired social interactions (HP:0000735) | 1.98257538 |
100 | Postural tremor (HP:0002174) | 1.97555179 |
101 | Difficulty climbing stairs (HP:0003551) | 1.97387504 |
102 | Spinal rigidity (HP:0003306) | 1.97009012 |
103 | Aqueductal stenosis (HP:0002410) | 1.96418278 |
104 | Distal sensory impairment (HP:0002936) | 1.95944826 |
105 | Abnormality of saccadic eye movements (HP:0000570) | 1.95505874 |
106 | Broad-based gait (HP:0002136) | 1.95248411 |
107 | EMG: neuropathic changes (HP:0003445) | 1.93349463 |
108 | Morphological abnormality of the pyramidal tract (HP:0002062) | 1.92945427 |
109 | Hypoventilation (HP:0002791) | 1.92173245 |
110 | Abnormal eating behavior (HP:0100738) | 1.89230660 |
111 | Shallow orbits (HP:0000586) | 1.87968183 |
112 | Spastic paraplegia (HP:0001258) | 1.87728316 |
113 | Generalized tonic-clonic seizures (HP:0002069) | 1.86256039 |
114 | Pointed chin (HP:0000307) | 1.86055586 |
115 | Limb dystonia (HP:0002451) | 1.85528188 |
116 | Asymmetric septal hypertrophy (HP:0001670) | 1.84977896 |
117 | Decreased number of peripheral myelinated nerve fibers (HP:0003380) | 1.84859109 |
118 | Hemiplegia (HP:0002301) | 1.83842700 |
119 | Mitral regurgitation (HP:0001653) | 1.83650000 |
120 | Abnormality of the periventricular white matter (HP:0002518) | 1.83077514 |
121 | Sudden death (HP:0001699) | 1.81228431 |
122 | Neoplasm of the heart (HP:0100544) | 1.78288124 |
123 | Flat cornea (HP:0007720) | 1.78066356 |
124 | Loss of speech (HP:0002371) | 1.77977807 |
125 | Excessive salivation (HP:0003781) | 1.77174788 |
126 | Drooling (HP:0002307) | 1.77174788 |
127 | Abnormal atrioventricular conduction (HP:0005150) | 1.77064809 |
128 | Spinal canal stenosis (HP:0003416) | 1.77048632 |
129 | Diminished motivation (HP:0000745) | 1.76725225 |
130 | Hand muscle atrophy (HP:0009130) | 1.76676170 |
131 | Scapular winging (HP:0003691) | 1.76270775 |
132 | Nuclear cataract (HP:0100018) | 1.75683109 |
133 | Clumsiness (HP:0002312) | 1.75441155 |
134 | Rigidity (HP:0002063) | 1.74475163 |
135 | Obstructive sleep apnea (HP:0002870) | 1.74370473 |
136 | Bowel incontinence (HP:0002607) | 1.74369788 |
137 | Heart block (HP:0012722) | 1.74031524 |
138 | Precocious puberty (HP:0000826) | 1.73287534 |
139 | Buphthalmos (HP:0000557) | 1.73102028 |
140 | EMG: myopathic abnormalities (HP:0003458) | 1.73017034 |
141 | Stereotypic behavior (HP:0000733) | 1.72832827 |
142 | Increased cerebral lipofuscin (HP:0011813) | 1.71207270 |
143 | Inappropriate behavior (HP:0000719) | 1.70785346 |
144 | Atonic seizures (HP:0010819) | 1.70428788 |
145 | J-shaped sella turcica (HP:0002680) | 1.70415263 |
146 | Bell-shaped thorax (HP:0001591) | 1.70181774 |
147 | Visceral angiomatosis (HP:0100761) | 1.69963284 |
148 | Renovascular hypertension (HP:0100817) | 1.66976027 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MARK1 | 3.39046003 |
2 | STK39 | 2.86822060 |
3 | PRKD3 | 2.85225981 |
4 | MAP3K9 | 2.64171268 |
5 | PAK6 | 2.45385003 |
6 | EPHB1 | 2.43196668 |
7 | SIK1 | 2.07260522 |
8 | NTRK3 | 2.03522216 |
9 | NTRK1 | 2.01723106 |
10 | WNK1 | 2.01412010 |
11 | TYRO3 | 1.94411412 |
12 | EPHA4 | 1.90482867 |
13 | KSR2 | 1.85984154 |
14 | ICK | 1.84772416 |
15 | EEF2K | 1.80623284 |
16 | UHMK1 | 1.75370026 |
17 | MAP3K4 | 1.73705089 |
18 | PKN1 | 1.71545772 |
19 | PHKG2 | 1.70284392 |
20 | PHKG1 | 1.70284392 |
21 | MAPKAPK5 | 1.68459987 |
22 | NTRK2 | 1.64314571 |
23 | OXSR1 | 1.64027937 |
24 | MINK1 | 1.63296698 |
25 | CAMK1G | 1.56460243 |
26 | CAMKK1 | 1.47440664 |
27 | FGFR2 | 1.46228334 |
28 | DAPK2 | 1.44886687 |
29 | SGK223 | 1.43905977 |
30 | SGK494 | 1.43905977 |
31 | CASK | 1.41851061 |
32 | MARK2 | 1.41682488 |
33 | WNK4 | 1.35867197 |
34 | CDK5 | 1.34373794 |
35 | MAPK12 | 1.31207631 |
36 | PRKCH | 1.21541147 |
37 | SIK2 | 1.20979868 |
38 | PKN2 | 1.20143523 |
39 | OBSCN | 1.19631959 |
40 | MAPK13 | 1.15505124 |
41 | STK38 | 1.14060057 |
42 | RET | 1.13557888 |
43 | LIMK1 | 1.13042127 |
44 | MAP3K2 | 1.12963790 |
45 | TRIB3 | 1.12320061 |
46 | PRPF4B | 1.12016628 |
47 | PNCK | 1.11885114 |
48 | DDR2 | 1.06362867 |
49 | MAP3K7 | 1.06356300 |
50 | LMTK2 | 1.06240294 |
51 | RIPK1 | 1.05594624 |
52 | ROCK2 | 1.01536758 |
53 | ALK | 0.98333238 |
54 | BMX | 0.96421819 |
55 | CSNK1G2 | 0.96372869 |
56 | LATS2 | 0.96343942 |
57 | DMPK | 0.95658050 |
58 | TNK2 | 0.92328617 |
59 | CDK15 | 0.91993121 |
60 | CDK14 | 0.89807511 |
61 | TESK1 | 0.89153509 |
62 | STK11 | 0.88423972 |
63 | PRKD2 | 0.87333612 |
64 | PRKD1 | 0.86995876 |
65 | CSNK1A1L | 0.86682844 |
66 | CDK18 | 0.85487329 |
67 | PAK3 | 0.85442771 |
68 | CDK19 | 0.84984307 |
69 | TAOK1 | 0.83224173 |
70 | EPHB2 | 0.82767825 |
71 | CDK11A | 0.81148785 |
72 | PTK2 | 0.80737643 |
73 | MAP3K11 | 0.79018681 |
74 | FES | 0.77288155 |
75 | CAMK1D | 0.77249687 |
76 | PDPK1 | 0.76951264 |
77 | SMG1 | 0.76618457 |
78 | PDGFRA | 0.74779619 |
79 | SGK2 | 0.74776167 |
80 | MTOR | 0.74357240 |
81 | CAMK2B | 0.73988864 |
82 | MAP2K4 | 0.72207119 |
83 | MAP2K7 | 0.70911269 |
84 | PDGFRB | 0.69861959 |
85 | FGR | 0.69513493 |
86 | FYN | 0.69113026 |
87 | DYRK2 | 0.67276767 |
88 | ARAF | 0.67046311 |
89 | CSNK1G3 | 0.66661520 |
90 | PDK1 | 0.66363835 |
91 | KSR1 | 0.65858596 |
92 | CLK1 | 0.64961094 |
93 | CAMK2A | 0.62877091 |
94 | FGFR4 | 0.62859004 |
95 | ERBB2 | 0.62780825 |
96 | MUSK | 0.62743742 |
97 | CAMK4 | 0.62147870 |
98 | CDC42BPA | 0.61956875 |
99 | SGK3 | 0.61037870 |
100 | MET | 0.60819240 |
101 | SGK1 | 0.60359204 |
102 | MAP2K6 | 0.60055084 |
103 | GRK5 | 0.60000686 |
104 | CAMK2D | 0.59281362 |
105 | DYRK1A | 0.59268693 |
106 | PINK1 | 0.58962394 |
107 | HIPK2 | 0.56219177 |
108 | MAPK10 | 0.55710992 |
109 | TIE1 | 0.54360436 |
110 | PRKAA1 | 0.51429100 |
111 | ROCK1 | 0.50879936 |
112 | PRKCZ | 0.50377162 |
113 | MAPKAPK3 | 0.50334093 |
114 | DYRK1B | 0.50268256 |
115 | RIPK4 | 0.49997494 |
116 | TESK2 | 0.49985408 |
117 | MAPK7 | 0.49634271 |
118 | CAMK2G | 0.49414232 |
119 | ERN1 | 0.47677124 |
120 | PTK6 | 0.47507630 |
121 | PTK2B | 0.47238409 |
122 | MAP3K6 | 0.47057472 |
123 | NEK6 | 0.46890115 |
124 | RPS6KC1 | 0.46862611 |
125 | RPS6KL1 | 0.46862611 |
126 | MAPK4 | 0.46742120 |
127 | RPS6KA3 | 0.46062945 |
128 | RPS6KA2 | 0.44597859 |
129 | MAPK8 | 0.44585355 |
130 | PRKCG | 0.44495784 |
131 | TTN | 0.44120069 |
132 | MAP3K13 | 0.44073460 |
133 | CSNK1G1 | 0.43613623 |
134 | MAP3K1 | 0.42927309 |
135 | CSNK1D | 0.41190252 |
136 | CAMK1 | 0.41168317 |
137 | TNIK | 0.39556041 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.15075318 |
2 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.14074776 |
3 | GABAergic synapse_Homo sapiens_hsa04727 | 2.00605780 |
4 | Olfactory transduction_Homo sapiens_hsa04740 | 1.97808938 |
5 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.93126428 |
6 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.89132875 |
7 | Circadian entrainment_Homo sapiens_hsa04713 | 1.88938435 |
8 | Morphine addiction_Homo sapiens_hsa05032 | 1.81523065 |
9 | Axon guidance_Homo sapiens_hsa04360 | 1.68019135 |
10 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.64619707 |
11 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.63873157 |
12 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.61945617 |
13 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.60817129 |
14 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.57742867 |
15 | Nicotine addiction_Homo sapiens_hsa05033 | 1.57431127 |
16 | Long-term potentiation_Homo sapiens_hsa04720 | 1.56269800 |
17 | Salivary secretion_Homo sapiens_hsa04970 | 1.54856590 |
18 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.52960393 |
19 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.48341533 |
20 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.41599079 |
21 | Long-term depression_Homo sapiens_hsa04730 | 1.37381708 |
22 | Cocaine addiction_Homo sapiens_hsa05030 | 1.37172376 |
23 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.36884438 |
24 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.35977974 |
25 | Renin secretion_Homo sapiens_hsa04924 | 1.31745332 |
26 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.30500568 |
27 | Gap junction_Homo sapiens_hsa04540 | 1.27877936 |
28 | Insulin secretion_Homo sapiens_hsa04911 | 1.25916282 |
29 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.25657568 |
30 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.24618620 |
31 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 1.21258015 |
32 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.20008421 |
33 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.19973005 |
34 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.19899162 |
35 | Glioma_Homo sapiens_hsa05214 | 1.18368552 |
36 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.16949211 |
37 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.16391852 |
38 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.13995642 |
39 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.12537925 |
40 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.09733346 |
41 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.08959955 |
42 | Endocytosis_Homo sapiens_hsa04144 | 1.08191493 |
43 | Insulin signaling pathway_Homo sapiens_hsa04910 | 1.05284110 |
44 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.02030369 |
45 | AMPK signaling pathway_Homo sapiens_hsa04152 | 1.00009509 |
46 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.99618917 |
47 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.98765370 |
48 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.97435159 |
49 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.95796475 |
50 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.90611782 |
51 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.88720443 |
52 | Taste transduction_Homo sapiens_hsa04742 | 0.88052078 |
53 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.87895371 |
54 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.87808438 |
55 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.86949961 |
56 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.86949627 |
57 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.86632075 |
58 | Melanogenesis_Homo sapiens_hsa04916 | 0.86399557 |
59 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.86128288 |
60 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.84923832 |
61 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.84424261 |
62 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.84308566 |
63 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.82862175 |
64 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.82277163 |
65 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.81457945 |
66 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.80525812 |
67 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.79644420 |
68 | Other glycan degradation_Homo sapiens_hsa00511 | 0.79266209 |
69 | Tight junction_Homo sapiens_hsa04530 | 0.77129012 |
70 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.73290098 |
71 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.72765872 |
72 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.72629605 |
73 | Endometrial cancer_Homo sapiens_hsa05213 | 0.72303043 |
74 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.70772950 |
75 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.70718892 |
76 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.70369089 |
77 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.70262589 |
78 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.67290586 |
79 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.64603470 |
80 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.64544686 |
81 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.64191236 |
82 | Insulin resistance_Homo sapiens_hsa04931 | 0.64074925 |
83 | Lysosome_Homo sapiens_hsa04142 | 0.64015110 |
84 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.63700197 |
85 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.63690764 |
86 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.63504685 |
87 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.63439016 |
88 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.62198209 |
89 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.61713833 |
90 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.61622485 |
91 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.61446312 |
92 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.61273363 |
93 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.60725662 |
94 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.60311869 |
95 | Focal adhesion_Homo sapiens_hsa04510 | 0.59871328 |
96 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.58860001 |
97 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.58356249 |
98 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.58010909 |
99 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.57094754 |
100 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.56897531 |
101 | Histidine metabolism_Homo sapiens_hsa00340 | 0.56828097 |
102 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.56762298 |
103 | Prion diseases_Homo sapiens_hsa05020 | 0.55468183 |
104 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.54980360 |
105 | Platelet activation_Homo sapiens_hsa04611 | 0.52786407 |
106 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.52726802 |
107 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.51333546 |
108 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.51319726 |
109 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.51306282 |
110 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.50799967 |
111 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.50097421 |
112 | Mineral absorption_Homo sapiens_hsa04978 | 0.50003160 |
113 | Salmonella infection_Homo sapiens_hsa05132 | 0.49876795 |
114 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.49503134 |
115 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.48774556 |
116 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.48508226 |
117 | Amoebiasis_Homo sapiens_hsa05146 | 0.48431980 |
118 | Adherens junction_Homo sapiens_hsa04520 | 0.48412812 |
119 | Bile secretion_Homo sapiens_hsa04976 | 0.48175268 |
120 | Circadian rhythm_Homo sapiens_hsa04710 | 0.46904259 |
121 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.46887387 |