

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | mitotic metaphase plate congression (GO:0007080) | 5.77797746 |
| 2 | chromatin remodeling at centromere (GO:0031055) | 5.73891083 |
| 3 | regulation of mitotic spindle checkpoint (GO:1903504) | 5.29450465 |
| 4 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 5.29450465 |
| 5 | DNA double-strand break processing (GO:0000729) | 5.27319376 |
| 6 | CENP-A containing nucleosome assembly (GO:0034080) | 5.17529176 |
| 7 | DNA replication checkpoint (GO:0000076) | 5.09046264 |
| 8 | metaphase plate congression (GO:0051310) | 5.00600807 |
| 9 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 4.86923841 |
| 10 | histone exchange (GO:0043486) | 4.81415453 |
| 11 | establishment of integrated proviral latency (GO:0075713) | 4.64368726 |
| 12 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 4.47491726 |
| 13 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 4.39119524 |
| 14 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 4.39119524 |
| 15 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 4.39119524 |
| 16 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 4.39119524 |
| 17 | negative regulation of sister chromatid segregation (GO:0033046) | 4.39119524 |
| 18 | negative regulation of DNA recombination (GO:0045910) | 4.33953295 |
| 19 | regulation of helicase activity (GO:0051095) | 4.32506221 |
| 20 | protein localization to kinetochore (GO:0034501) | 4.27500740 |
| 21 | telomere maintenance via semi-conservative replication (GO:0032201) | 4.26478237 |
| 22 | nuclear pore complex assembly (GO:0051292) | 4.26144913 |
| 23 | IMP biosynthetic process (GO:0006188) | 4.25942241 |
| 24 | negative regulation of chromosome segregation (GO:0051985) | 4.25108269 |
| 25 | mitotic spindle checkpoint (GO:0071174) | 4.23438901 |
| 26 | nuclear pore organization (GO:0006999) | 4.21645265 |
| 27 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.20896660 |
| 28 | purine nucleobase biosynthetic process (GO:0009113) | 4.19291141 |
| 29 | spindle checkpoint (GO:0031577) | 4.13580151 |
| 30 | DNA replication-independent nucleosome organization (GO:0034724) | 4.11888680 |
| 31 | DNA replication-independent nucleosome assembly (GO:0006336) | 4.11888680 |
| 32 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 4.10441256 |
| 33 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 4.10441256 |
| 34 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 4.08905062 |
| 35 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 4.08905062 |
| 36 | mitotic recombination (GO:0006312) | 4.05851392 |
| 37 | protein neddylation (GO:0045116) | 3.99493904 |
| 38 | DNA strand elongation (GO:0022616) | 3.97831651 |
| 39 | lysine metabolic process (GO:0006553) | 3.95959115 |
| 40 | lysine catabolic process (GO:0006554) | 3.95959115 |
| 41 | proteasome assembly (GO:0043248) | 3.93709732 |
| 42 | telomere maintenance via recombination (GO:0000722) | 3.87001518 |
| 43 | establishment of chromosome localization (GO:0051303) | 3.86430297 |
| 44 | heterochromatin organization (GO:0070828) | 3.85294795 |
| 45 | regulation of mitotic sister chromatid separation (GO:0010965) | 3.79967686 |
| 46 | regulation of mitotic sister chromatid segregation (GO:0033047) | 3.79967686 |
| 47 | regulation of sister chromatid segregation (GO:0033045) | 3.79967686 |
| 48 | kinetochore organization (GO:0051383) | 3.78797332 |
| 49 | nucleobase biosynthetic process (GO:0046112) | 3.77267214 |
| 50 | synapsis (GO:0007129) | 3.75322804 |
| 51 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.74919755 |
| 52 | histone mRNA metabolic process (GO:0008334) | 3.74361426 |
| 53 | mitotic spindle assembly checkpoint (GO:0007094) | 3.74153349 |
| 54 | telomere maintenance via telomerase (GO:0007004) | 3.73957297 |
| 55 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.70366952 |
| 56 | non-recombinational repair (GO:0000726) | 3.70303898 |
| 57 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.70303898 |
| 58 | IMP metabolic process (GO:0046040) | 3.69896391 |
| 59 | mitotic G2/M transition checkpoint (GO:0044818) | 3.68273211 |
| 60 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.66370688 |
| 61 | isotype switching (GO:0045190) | 3.66370688 |
| 62 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.66370688 |
| 63 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.66344964 |
| 64 | regulation of chromosome segregation (GO:0051983) | 3.65845189 |
| 65 | spindle assembly checkpoint (GO:0071173) | 3.64580266 |
| 66 | response to X-ray (GO:0010165) | 3.64039758 |
| 67 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.62122448 |
| 68 | negative regulation of mitosis (GO:0045839) | 3.56626847 |
| 69 | kinetochore assembly (GO:0051382) | 3.55020945 |
| 70 | regulation of spindle checkpoint (GO:0090231) | 3.53595620 |
| 71 | telomere maintenance via telomere lengthening (GO:0010833) | 3.52573305 |
| 72 | protein K6-linked ubiquitination (GO:0085020) | 3.51516102 |
| 73 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.51411999 |
| 74 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.48697654 |
| 75 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 3.44103632 |
| 76 | establishment of viral latency (GO:0019043) | 3.42845651 |
| 77 | negative regulation of ligase activity (GO:0051352) | 3.40454272 |
| 78 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.40454272 |
| 79 | ribosome assembly (GO:0042255) | 3.38067938 |
| 80 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.34803442 |
| 81 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.34803442 |
| 82 | replication fork processing (GO:0031297) | 3.32897968 |
| 83 | protein localization to chromosome, centromeric region (GO:0071459) | 3.32750819 |
| 84 | negative regulation of fibroblast apoptotic process (GO:2000270) | 3.29210975 |
| 85 | mitotic sister chromatid cohesion (GO:0007064) | 3.28747841 |
| 86 | female gonad development (GO:0008585) | 3.26137593 |
| 87 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.25613578 |
| 88 | negative regulation of nuclear division (GO:0051784) | 3.24330990 |
| 89 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.20286159 |
| 90 | cullin deneddylation (GO:0010388) | 3.17635355 |
| 91 | postreplication repair (GO:0006301) | 3.17315807 |
| 92 | pore complex assembly (GO:0046931) | 3.15026229 |
| 93 | sister chromatid segregation (GO:0000819) | 3.11953014 |
| 94 | RNA-dependent DNA replication (GO:0006278) | 3.10794526 |
| 95 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.10432549 |
| 96 | DNA replication initiation (GO:0006270) | 3.10039246 |
| 97 | termination of RNA polymerase III transcription (GO:0006386) | 3.07122743 |
| 98 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.07122743 |
| 99 | mitotic sister chromatid segregation (GO:0000070) | 3.06012640 |
| 100 | DNA ligation (GO:0006266) | 3.04630369 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 8.09316797 |
| 2 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 4.91125229 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.02384318 |
| 4 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 3.69324780 |
| 5 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 3.38462231 |
| 6 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.20919885 |
| 7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.11791212 |
| 8 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.90387334 |
| 9 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.69991988 |
| 10 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.48622768 |
| 11 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.46403267 |
| 12 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.43322712 |
| 13 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.40444970 |
| 14 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.39010463 |
| 15 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.32604266 |
| 16 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.29788413 |
| 17 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 2.26495102 |
| 18 | VDR_22108803_ChIP-Seq_LS180_Human | 2.23298206 |
| 19 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.16065054 |
| 20 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.15420124 |
| 21 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.02439007 |
| 22 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 2.00617501 |
| 23 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.96374825 |
| 24 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.95303352 |
| 25 | EWS_26573619_Chip-Seq_HEK293_Human | 1.94288620 |
| 26 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.94172855 |
| 27 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.93188561 |
| 28 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.87755349 |
| 29 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.84395454 |
| 30 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.79912537 |
| 31 | FUS_26573619_Chip-Seq_HEK293_Human | 1.75365473 |
| 32 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.74877646 |
| 33 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.70321696 |
| 34 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.69803092 |
| 35 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.67985892 |
| 36 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.67711213 |
| 37 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.65373279 |
| 38 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.63685536 |
| 39 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.58641756 |
| 40 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.53760926 |
| 41 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.53465375 |
| 42 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.52961829 |
| 43 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.49413507 |
| 44 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.49255937 |
| 45 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.47696777 |
| 46 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.41525424 |
| 47 | P300_19829295_ChIP-Seq_ESCs_Human | 1.40525941 |
| 48 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.40058594 |
| 49 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.39826862 |
| 50 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.39133974 |
| 51 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.36052854 |
| 52 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.27651587 |
| 53 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.26257882 |
| 54 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.25360483 |
| 55 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.25220687 |
| 56 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.22493302 |
| 57 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.21316962 |
| 58 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.20130056 |
| 59 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.18315770 |
| 60 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.14627138 |
| 61 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.13574463 |
| 62 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.12981546 |
| 63 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.11162326 |
| 64 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.11053637 |
| 65 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.10918418 |
| 66 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.10036115 |
| 67 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.09416772 |
| 68 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.08630528 |
| 69 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.06849440 |
| 70 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.06413007 |
| 71 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.03660223 |
| 72 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.03660223 |
| 73 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.03660223 |
| 74 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.03293237 |
| 75 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.00373146 |
| 76 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.00190571 |
| 77 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.99829376 |
| 78 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.97654956 |
| 79 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.96360844 |
| 80 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.93735064 |
| 81 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.93673656 |
| 82 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.93132959 |
| 83 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 0.92632244 |
| 84 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 0.91891690 |
| 85 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.91772793 |
| 86 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.91649994 |
| 87 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 0.90923391 |
| 88 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.89260866 |
| 89 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.87527752 |
| 90 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.86800486 |
| 91 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.85913082 |
| 92 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.82812131 |
| 93 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.82779004 |
| 94 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 0.82660325 |
| 95 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.82342431 |
| 96 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.79902785 |
| 97 | TCF3_18692474_ChIP-Seq_MESCs_Mouse | 0.79174438 |
| 98 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.78263565 |
| 99 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.76565918 |
| 100 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.75838224 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0010094_abnormal_chromosome_stability | 4.83760893 |
| 2 | MP0008057_abnormal_DNA_replication | 4.74550080 |
| 3 | MP0003941_abnormal_skin_development | 4.72731845 |
| 4 | MP0004957_abnormal_blastocyst_morpholog | 4.32791375 |
| 5 | MP0003693_abnormal_embryo_hatching | 4.05984838 |
| 6 | MP0003111_abnormal_nucleus_morphology | 3.89545837 |
| 7 | MP0008058_abnormal_DNA_repair | 3.87394284 |
| 8 | MP0003123_paternal_imprinting | 3.08800761 |
| 9 | MP0008932_abnormal_embryonic_tissue | 3.05551858 |
| 10 | MP0003077_abnormal_cell_cycle | 2.98303910 |
| 11 | MP0001188_hyperpigmentation | 2.97380688 |
| 12 | MP0003718_maternal_effect | 2.90187098 |
| 13 | MP0008007_abnormal_cellular_replicative | 2.60606722 |
| 14 | MP0008877_abnormal_DNA_methylation | 2.57900280 |
| 15 | MP0009697_abnormal_copulation | 2.12235764 |
| 16 | MP0009672_abnormal_birth_weight | 2.10607498 |
| 17 | MP0006072_abnormal_retinal_apoptosis | 2.09326120 |
| 18 | MP0003121_genomic_imprinting | 2.07168021 |
| 19 | MP0003890_abnormal_embryonic-extraembry | 1.92240643 |
| 20 | MP0003136_yellow_coat_color | 1.89332449 |
| 21 | MP0000579_abnormal_nail_morphology | 1.88544135 |
| 22 | MP0003567_abnormal_fetal_cardiomyocyte | 1.85342085 |
| 23 | MP0003195_calcinosis | 1.71348976 |
| 24 | MP0010307_abnormal_tumor_latency | 1.68028433 |
| 25 | MP0001293_anophthalmia | 1.63987660 |
| 26 | MP0003786_premature_aging | 1.62431208 |
| 27 | MP0006292_abnormal_olfactory_placode | 1.55752234 |
| 28 | MP0003646_muscle_fatigue | 1.52663625 |
| 29 | MP0003937_abnormal_limbs/digits/tail_de | 1.51575402 |
| 30 | MP0001177_atelectasis | 1.42268397 |
| 31 | MP0004133_heterotaxia | 1.38493568 |
| 32 | MP0001730_embryonic_growth_arrest | 1.35154955 |
| 33 | MP0002254_reproductive_system_inflammat | 1.33939890 |
| 34 | MP0004197_abnormal_fetal_growth/weight/ | 1.31465259 |
| 35 | MP0000350_abnormal_cell_proliferation | 1.28568716 |
| 36 | MP0002090_abnormal_vision | 1.27188618 |
| 37 | MP0002751_abnormal_autonomic_nervous | 1.25194902 |
| 38 | MP0009703_decreased_birth_body | 1.23522895 |
| 39 | MP0006035_abnormal_mitochondrial_morpho | 1.23342496 |
| 40 | MP0003787_abnormal_imprinting | 1.20438888 |
| 41 | MP0002102_abnormal_ear_morphology | 1.12704267 |
| 42 | MP0003137_abnormal_impulse_conducting | 1.12501590 |
| 43 | MP0006054_spinal_hemorrhage | 1.11965639 |
| 44 | MP0001697_abnormal_embryo_size | 1.08871216 |
| 45 | MP0002085_abnormal_embryonic_tissue | 1.08794944 |
| 46 | MP0005395_other_phenotype | 1.08415597 |
| 47 | MP0002084_abnormal_developmental_patter | 1.08050550 |
| 48 | MP0001929_abnormal_gametogenesis | 1.07835753 |
| 49 | MP0003119_abnormal_digestive_system | 1.06448703 |
| 50 | MP0002796_impaired_skin_barrier | 1.06157313 |
| 51 | MP0004215_abnormal_myocardial_fiber | 1.05011523 |
| 52 | MP0010352_gastrointestinal_tract_polyps | 1.03578308 |
| 53 | MP0006036_abnormal_mitochondrial_physio | 0.98270719 |
| 54 | MP0003806_abnormal_nucleotide_metabolis | 0.98255347 |
| 55 | MP0001485_abnormal_pinna_reflex | 0.96076939 |
| 56 | MP0002210_abnormal_sex_determination | 0.95042844 |
| 57 | MP0005380_embryogenesis_phenotype | 0.93518123 |
| 58 | MP0001672_abnormal_embryogenesis/_devel | 0.93518123 |
| 59 | MP0002080_prenatal_lethality | 0.92098074 |
| 60 | MP0002736_abnormal_nociception_after | 0.91696925 |
| 61 | MP0008789_abnormal_olfactory_epithelium | 0.88186632 |
| 62 | MP0002111_abnormal_tail_morphology | 0.87288600 |
| 63 | MP0000647_abnormal_sebaceous_gland | 0.87214338 |
| 64 | MP0001286_abnormal_eye_development | 0.86730682 |
| 65 | MP0000653_abnormal_sex_gland | 0.86510544 |
| 66 | MP0005220_abnormal_exocrine_pancreas | 0.86483337 |
| 67 | MP0001145_abnormal_male_reproductive | 0.85454986 |
| 68 | MP0002233_abnormal_nose_morphology | 0.85212675 |
| 69 | MP0005253_abnormal_eye_physiology | 0.81206447 |
| 70 | MP0010030_abnormal_orbit_morphology | 0.79739418 |
| 71 | MP0001299_abnormal_eye_distance/ | 0.79476380 |
| 72 | MP0005367_renal/urinary_system_phenotyp | 0.74351113 |
| 73 | MP0000516_abnormal_urinary_system | 0.74351113 |
| 74 | MP0000313_abnormal_cell_death | 0.74244867 |
| 75 | MP0001119_abnormal_female_reproductive | 0.72656202 |
| 76 | MP0002396_abnormal_hematopoietic_system | 0.72494816 |
| 77 | MP0010234_abnormal_vibrissa_follicle | 0.72407269 |
| 78 | MP0002697_abnormal_eye_size | 0.69969907 |
| 79 | MP0002938_white_spotting | 0.69232793 |
| 80 | MP0010678_abnormal_skin_adnexa | 0.66168298 |
| 81 | MP0001529_abnormal_vocalization | 0.64439363 |
| 82 | MP0003221_abnormal_cardiomyocyte_apopto | 0.63015654 |
| 83 | MP0001324_abnormal_eye_pigmentation | 0.61914951 |
| 84 | MP0002160_abnormal_reproductive_system | 0.61477537 |
| 85 | MP0003698_abnormal_male_reproductive | 0.61350212 |
| 86 | MP0005332_abnormal_amino_acid | 0.60913277 |
| 87 | MP0005551_abnormal_eye_electrophysiolog | 0.60538068 |
| 88 | MP0002019_abnormal_tumor_incidence | 0.60026724 |
| 89 | MP0002086_abnormal_extraembryonic_tissu | 0.59929940 |
| 90 | MP0002088_abnormal_embryonic_growth/wei | 0.58621059 |
| 91 | MP0003984_embryonic_growth_retardation | 0.57840332 |
| 92 | MP0005075_abnormal_melanosome_morpholog | 0.56306004 |
| 93 | MP0003755_abnormal_palate_morphology | 0.55727842 |
| 94 | MP0004147_increased_porphyrin_level | 0.55441692 |
| 95 | MP0000383_abnormal_hair_follicle | 0.54775830 |
| 96 | MP0005389_reproductive_system_phenotype | 0.52381179 |
| 97 | MP0003699_abnormal_female_reproductive | 0.52362981 |
| 98 | MP0001186_pigmentation_phenotype | 0.51890866 |
| 99 | MP0005391_vision/eye_phenotype | 0.51592244 |
| 100 | MP0003186_abnormal_redox_activity | 0.50817786 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 5.60564275 |
| 2 | Chromsome breakage (HP:0040012) | 5.17055506 |
| 3 | Abnormality of the labia minora (HP:0012880) | 4.87463678 |
| 4 | Birth length less than 3rd percentile (HP:0003561) | 4.82425866 |
| 5 | Abnormality of chromosome stability (HP:0003220) | 4.24920445 |
| 6 | Colon cancer (HP:0003003) | 4.03499750 |
| 7 | Meckel diverticulum (HP:0002245) | 3.85336034 |
| 8 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 3.65231747 |
| 9 | Spastic diplegia (HP:0001264) | 3.63959736 |
| 10 | Abnormality of the ileum (HP:0001549) | 3.60907079 |
| 11 | Agnosia (HP:0010524) | 3.51167525 |
| 12 | Abnormality of the preputium (HP:0100587) | 3.50099176 |
| 13 | Multiple enchondromatosis (HP:0005701) | 3.34030046 |
| 14 | Supernumerary spleens (HP:0009799) | 3.30197445 |
| 15 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 3.24324551 |
| 16 | Rhabdomyosarcoma (HP:0002859) | 3.23846960 |
| 17 | Ependymoma (HP:0002888) | 3.22656301 |
| 18 | Duodenal stenosis (HP:0100867) | 3.15563710 |
| 19 | Small intestinal stenosis (HP:0012848) | 3.15563710 |
| 20 | Nephroblastoma (Wilms tumor) (HP:0002667) | 3.15060125 |
| 21 | Methylmalonic acidemia (HP:0002912) | 3.09409751 |
| 22 | Medulloblastoma (HP:0002885) | 3.07542321 |
| 23 | Abnormal lung lobation (HP:0002101) | 3.01367079 |
| 24 | Biliary tract neoplasm (HP:0100574) | 2.99015341 |
| 25 | Embryonal renal neoplasm (HP:0011794) | 2.96280892 |
| 26 | Abnormality of serum amino acid levels (HP:0003112) | 2.80865720 |
| 27 | Stenosis of the external auditory canal (HP:0000402) | 2.72881089 |
| 28 | Neoplasm of the adrenal gland (HP:0100631) | 2.72138149 |
| 29 | Abnormality of the duodenum (HP:0002246) | 2.65312524 |
| 30 | Absent radius (HP:0003974) | 2.55778044 |
| 31 | Volvulus (HP:0002580) | 2.52792870 |
| 32 | Abnormality of methionine metabolism (HP:0010901) | 2.49466707 |
| 33 | Ovarian neoplasm (HP:0100615) | 2.47720601 |
| 34 | Abnormality of the pons (HP:0007361) | 2.47013823 |
| 35 | Methylmalonic aciduria (HP:0012120) | 2.44562635 |
| 36 | Congenital, generalized hypertrichosis (HP:0004540) | 2.41811645 |
| 37 | Absent forearm bone (HP:0003953) | 2.40900272 |
| 38 | Aplasia involving forearm bones (HP:0009822) | 2.40900272 |
| 39 | Clubbing of toes (HP:0100760) | 2.40662265 |
| 40 | Sloping forehead (HP:0000340) | 2.38144764 |
| 41 | Neoplasm of the colon (HP:0100273) | 2.34786675 |
| 42 | Glioma (HP:0009733) | 2.34159089 |
| 43 | Acanthocytosis (HP:0001927) | 2.32727422 |
| 44 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.24749281 |
| 45 | Carpal bone hypoplasia (HP:0001498) | 2.24599721 |
| 46 | Abolished electroretinogram (ERG) (HP:0000550) | 2.24366728 |
| 47 | Cortical dysplasia (HP:0002539) | 2.22988489 |
| 48 | Progressive inability to walk (HP:0002505) | 2.22973192 |
| 49 | Hyperglycinemia (HP:0002154) | 2.19467718 |
| 50 | Hypoplasia of the pons (HP:0012110) | 2.17942551 |
| 51 | Ectopic kidney (HP:0000086) | 2.16991319 |
| 52 | Neoplasm of the oral cavity (HP:0100649) | 2.15328606 |
| 53 | Increased hepatocellular lipid droplets (HP:0006565) | 2.14802649 |
| 54 | Myelodysplasia (HP:0002863) | 2.13235133 |
| 55 | Breast carcinoma (HP:0003002) | 2.13131557 |
| 56 | Uterine neoplasm (HP:0010784) | 2.08770071 |
| 57 | Horseshoe kidney (HP:0000085) | 2.07971133 |
| 58 | Neoplasm of the small intestine (HP:0100833) | 2.07302541 |
| 59 | Lipid accumulation in hepatocytes (HP:0006561) | 2.07123312 |
| 60 | Triphalangeal thumb (HP:0001199) | 2.06670752 |
| 61 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.04654245 |
| 62 | Abnormality of the carotid arteries (HP:0005344) | 2.04207814 |
| 63 | Abnormal hair whorl (HP:0010721) | 2.00106068 |
| 64 | Abnormality of the astrocytes (HP:0100707) | 1.99117730 |
| 65 | Astrocytoma (HP:0009592) | 1.99117730 |
| 66 | Neoplasm of striated muscle (HP:0009728) | 1.97203161 |
| 67 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.96740665 |
| 68 | Abnormality of glycine metabolism (HP:0010895) | 1.96740665 |
| 69 | Megaloblastic anemia (HP:0001889) | 1.96176494 |
| 70 | Congenital stationary night blindness (HP:0007642) | 1.94952437 |
| 71 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.93730729 |
| 72 | Gastrointestinal carcinoma (HP:0002672) | 1.93730729 |
| 73 | Hypoglycemic seizures (HP:0002173) | 1.91562538 |
| 74 | Breast aplasia (HP:0100783) | 1.90995460 |
| 75 | Neoplasm of the rectum (HP:0100743) | 1.89893852 |
| 76 | Abnormality of homocysteine metabolism (HP:0010919) | 1.87346473 |
| 77 | Homocystinuria (HP:0002156) | 1.87346473 |
| 78 | Gonadotropin excess (HP:0000837) | 1.86947551 |
| 79 | Abnormality of vitamin B metabolism (HP:0004340) | 1.86113296 |
| 80 | Duplicated collecting system (HP:0000081) | 1.86032142 |
| 81 | Absent septum pellucidum (HP:0001331) | 1.81594799 |
| 82 | Clitoromegaly (HP:0000057) | 1.81007152 |
| 83 | Abnormality of the anterior horn cell (HP:0006802) | 1.79943314 |
| 84 | Degeneration of anterior horn cells (HP:0002398) | 1.79943314 |
| 85 | Hypoplastic female external genitalia (HP:0012815) | 1.79444503 |
| 86 | Acute encephalopathy (HP:0006846) | 1.77300198 |
| 87 | Symptomatic seizures (HP:0011145) | 1.77246409 |
| 88 | Oral leukoplakia (HP:0002745) | 1.76450630 |
| 89 | Aplasia/Hypoplasia of the breasts (HP:0010311) | 1.74787678 |
| 90 | Abnormality of the septum pellucidum (HP:0007375) | 1.74766560 |
| 91 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.74184916 |
| 92 | Dandy-Walker malformation (HP:0001305) | 1.73699584 |
| 93 | Bile duct proliferation (HP:0001408) | 1.72975788 |
| 94 | Abnormal biliary tract physiology (HP:0012439) | 1.72975788 |
| 95 | Sensory axonal neuropathy (HP:0003390) | 1.72248719 |
| 96 | Abnormality of the clitoris (HP:0000056) | 1.70734064 |
| 97 | Labial hypoplasia (HP:0000066) | 1.70026087 |
| 98 | Small hand (HP:0200055) | 1.68761181 |
| 99 | Acute necrotizing encephalopathy (HP:0006965) | 1.68165255 |
| 100 | Cafe-au-lait spot (HP:0000957) | 1.66670170 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | CDC7 | 4.00106314 |
| 2 | TTK | 3.76815512 |
| 3 | MKNK2 | 3.64279940 |
| 4 | EIF2AK3 | 3.61472768 |
| 5 | BUB1 | 3.49190746 |
| 6 | PLK3 | 3.27485581 |
| 7 | WNK3 | 3.25781571 |
| 8 | ZAK | 3.15187255 |
| 9 | MST4 | 3.05445200 |
| 10 | TSSK6 | 2.80237219 |
| 11 | SRPK1 | 2.69449352 |
| 12 | NUAK1 | 2.53401675 |
| 13 | MKNK1 | 2.52808289 |
| 14 | EIF2AK1 | 2.41127156 |
| 15 | WEE1 | 2.12910345 |
| 16 | BRSK2 | 2.08434837 |
| 17 | VRK1 | 2.07380517 |
| 18 | FRK | 1.93482189 |
| 19 | PLK1 | 1.87527561 |
| 20 | PLK4 | 1.86591273 |
| 21 | TNIK | 1.83415496 |
| 22 | NEK1 | 1.68786610 |
| 23 | PLK2 | 1.65286694 |
| 24 | VRK2 | 1.64518563 |
| 25 | ERBB3 | 1.61373781 |
| 26 | ACVR1B | 1.59945136 |
| 27 | TRIM28 | 1.54763381 |
| 28 | TAF1 | 1.50324034 |
| 29 | PBK | 1.40267534 |
| 30 | EIF2AK2 | 1.32760907 |
| 31 | BRAF | 1.31831181 |
| 32 | GRK1 | 1.25490885 |
| 33 | OXSR1 | 1.23994221 |
| 34 | STK16 | 1.16886596 |
| 35 | STK38L | 1.13624479 |
| 36 | BMPR1B | 1.10124485 |
| 37 | CHEK2 | 1.09083982 |
| 38 | CDK19 | 1.05886577 |
| 39 | TIE1 | 1.03062146 |
| 40 | ATR | 1.02225102 |
| 41 | ALK | 0.89428726 |
| 42 | ATM | 0.82369517 |
| 43 | STK10 | 0.81730813 |
| 44 | AURKB | 0.80680912 |
| 45 | BRSK1 | 0.80462286 |
| 46 | MAP3K10 | 0.80135321 |
| 47 | ERBB4 | 0.77392665 |
| 48 | DYRK3 | 0.74371070 |
| 49 | DYRK2 | 0.72574155 |
| 50 | CHEK1 | 0.69116444 |
| 51 | FGFR2 | 0.68756886 |
| 52 | TEC | 0.68602795 |
| 53 | CLK1 | 0.68085504 |
| 54 | INSRR | 0.65746348 |
| 55 | CDK3 | 0.65513751 |
| 56 | STK24 | 0.65447668 |
| 57 | STK3 | 0.64689698 |
| 58 | FLT3 | 0.60659360 |
| 59 | CSNK1G1 | 0.57834177 |
| 60 | CASK | 0.51335774 |
| 61 | PNCK | 0.51160702 |
| 62 | MAP3K8 | 0.50268519 |
| 63 | CDK1 | 0.47304935 |
| 64 | CSNK2A1 | 0.44344820 |
| 65 | NEK2 | 0.44271170 |
| 66 | MAP3K9 | 0.43984782 |
| 67 | PAK4 | 0.43940948 |
| 68 | NLK | 0.43467867 |
| 69 | FGFR1 | 0.43436677 |
| 70 | DMPK | 0.42113833 |
| 71 | CSNK2A2 | 0.41901659 |
| 72 | PRKCG | 0.40658703 |
| 73 | AURKA | 0.40435854 |
| 74 | PASK | 0.39995165 |
| 75 | CSNK1E | 0.39536831 |
| 76 | CDK2 | 0.39193346 |
| 77 | PRKDC | 0.38568263 |
| 78 | EPHA4 | 0.37204745 |
| 79 | NME1 | 0.35631590 |
| 80 | BRD4 | 0.33725612 |
| 81 | CSNK1G3 | 0.33626137 |
| 82 | TGFBR1 | 0.32619421 |
| 83 | BCR | 0.32542750 |
| 84 | CDK7 | 0.30808665 |
| 85 | STK4 | 0.29907617 |
| 86 | CSNK1G2 | 0.29532934 |
| 87 | ADRBK2 | 0.28140715 |
| 88 | PRKCI | 0.26366748 |
| 89 | STK39 | 0.24609276 |
| 90 | TLK1 | 0.24004515 |
| 91 | RPS6KA4 | 0.23323488 |
| 92 | CSNK1A1L | 0.22330011 |
| 93 | RPS6KA5 | 0.22190474 |
| 94 | DYRK1A | 0.21878762 |
| 95 | TGFBR2 | 0.21207584 |
| 96 | PINK1 | 0.18794698 |
| 97 | PDK2 | 0.17320201 |
| 98 | MELK | 0.16570367 |
| 99 | CDK6 | 0.16050000 |
| 100 | EGFR | 0.15830275 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Mismatch repair_Homo sapiens_hsa03430 | 4.69757759 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 4.18379315 |
| 3 | DNA replication_Homo sapiens_hsa03030 | 3.73987652 |
| 4 | Homologous recombination_Homo sapiens_hsa03440 | 3.34001064 |
| 5 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.33458196 |
| 6 | Non-homologous end-joining_Homo sapiens_hsa03450 | 3.30063807 |
| 7 | RNA polymerase_Homo sapiens_hsa03020 | 2.75586498 |
| 8 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.49454376 |
| 9 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.37628178 |
| 10 | Cell cycle_Homo sapiens_hsa04110 | 2.33806755 |
| 11 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.26933444 |
| 12 | RNA transport_Homo sapiens_hsa03013 | 2.25548425 |
| 13 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 2.11899414 |
| 14 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.11709910 |
| 15 | RNA degradation_Homo sapiens_hsa03018 | 2.07867583 |
| 16 | Spliceosome_Homo sapiens_hsa03040 | 2.02218773 |
| 17 | Protein export_Homo sapiens_hsa03060 | 1.92790806 |
| 18 | Basal transcription factors_Homo sapiens_hsa03022 | 1.81021986 |
| 19 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.77015470 |
| 20 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.73606826 |
| 21 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.71798025 |
| 22 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.69716258 |
| 23 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.56970839 |
| 24 | Base excision repair_Homo sapiens_hsa03410 | 1.55761367 |
| 25 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.49894201 |
| 26 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.44933165 |
| 27 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.41816763 |
| 28 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.41568521 |
| 29 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.40075231 |
| 30 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.28821363 |
| 31 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.28282030 |
| 32 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.23618448 |
| 33 | Purine metabolism_Homo sapiens_hsa00230 | 1.21695456 |
| 34 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.20508301 |
| 35 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.18696983 |
| 36 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.17451245 |
| 37 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.12862442 |
| 38 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.12567766 |
| 39 | Phototransduction_Homo sapiens_hsa04744 | 1.08951484 |
| 40 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.02559076 |
| 41 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.99063555 |
| 42 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.98548177 |
| 43 | Parkinsons disease_Homo sapiens_hsa05012 | 0.95351778 |
| 44 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.86787134 |
| 45 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.86473219 |
| 46 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.85919597 |
| 47 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.83380779 |
| 48 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.82026731 |
| 49 | Carbon metabolism_Homo sapiens_hsa01200 | 0.75955677 |
| 50 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.72730493 |
| 51 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.71549549 |
| 52 | Huntingtons disease_Homo sapiens_hsa05016 | 0.70625198 |
| 53 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.66060703 |
| 54 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.65317252 |
| 55 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.63592626 |
| 56 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.61971571 |
| 57 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.61774853 |
| 58 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.61553537 |
| 59 | Retinol metabolism_Homo sapiens_hsa00830 | 0.60624297 |
| 60 | Metabolic pathways_Homo sapiens_hsa01100 | 0.56110885 |
| 61 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.54208496 |
| 62 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.53274371 |
| 63 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.51492971 |
| 64 | Alzheimers disease_Homo sapiens_hsa05010 | 0.50083176 |
| 65 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.49341712 |
| 66 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.48352796 |
| 67 | Peroxisome_Homo sapiens_hsa04146 | 0.48299167 |
| 68 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.47313359 |
| 69 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.44832225 |
| 70 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.42821294 |
| 71 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.42702098 |
| 72 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.42607290 |
| 73 | Lysine degradation_Homo sapiens_hsa00310 | 0.41074131 |
| 74 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.40813372 |
| 75 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.40467865 |
| 76 | Ribosome_Homo sapiens_hsa03010 | 0.40066965 |
| 77 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.36051499 |
| 78 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.35290977 |
| 79 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.35188582 |
| 80 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.35109838 |
| 81 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.34113481 |
| 82 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.33524962 |
| 83 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.33482080 |
| 84 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.33391981 |
| 85 | Tight junction_Homo sapiens_hsa04530 | 0.32050286 |
| 86 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.28847651 |
| 87 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.28386338 |
| 88 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.27253152 |
| 89 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.25769527 |
| 90 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.24349247 |
| 91 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.23791887 |
| 92 | Nicotine addiction_Homo sapiens_hsa05033 | 0.21877919 |
| 93 | Alcoholism_Homo sapiens_hsa05034 | 0.21849494 |
| 94 | Sulfur relay system_Homo sapiens_hsa04122 | 0.21360924 |
| 95 | Galactose metabolism_Homo sapiens_hsa00052 | 0.20958184 |
| 96 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.20535432 |
| 97 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.19752130 |
| 98 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.19500713 |
| 99 | Taste transduction_Homo sapiens_hsa04742 | 0.18748506 |
| 100 | Olfactory transduction_Homo sapiens_hsa04740 | 0.18473625 |

