PALD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1adenosine receptor signaling pathway (GO:0001973)7.21620940
2regulation of posttranscriptional gene silencing (GO:0060147)6.19865654
3regulation of gene silencing by miRNA (GO:0060964)6.19865654
4regulation of gene silencing by RNA (GO:0060966)6.19865654
5positive regulation of SMAD protein import into nucleus (GO:0060391)5.63458002
6regulation of SMAD protein import into nucleus (GO:0060390)5.15392946
7negative regulation of myotube differentiation (GO:0010832)4.65917915
8paraxial mesoderm development (GO:0048339)4.64553062
9nuclear pore organization (GO:0006999)4.39137830
10positive regulation of myeloid leukocyte mediated immunity (GO:0002888)4.27468457
11basement membrane organization (GO:0071711)4.25320508
12regulation of chemokine-mediated signaling pathway (GO:0070099)4.00725737
13pre-miRNA processing (GO:0031054)3.99652146
14nuclear pore complex assembly (GO:0051292)3.97916945
15establishment of apical/basal cell polarity (GO:0035089)3.96866468
16regulation of hippo signaling (GO:0035330)3.73400271
17negative regulation of norepinephrine secretion (GO:0010700)3.72682150
18DNA replication-dependent nucleosome organization (GO:0034723)3.63642307
19DNA replication-dependent nucleosome assembly (GO:0006335)3.63642307
20cellular hyperosmotic response (GO:0071474)3.62026076
21protein complex localization (GO:0031503)3.61410388
22G-protein coupled purinergic receptor signaling pathway (GO:0035588)3.57016821
23DNA unwinding involved in DNA replication (GO:0006268)3.56732099
24cytoskeletal anchoring at plasma membrane (GO:0007016)3.54697141
25heterochromatin organization (GO:0070828)3.47221225
26negative regulation of blood vessel endothelial cell migration (GO:0043537)3.45345833
27regulation of translational fidelity (GO:0006450)3.43912032
28protein localization to kinetochore (GO:0034501)3.42523129
29positive regulation of chemokine secretion (GO:0090197)3.42108249
30determination of adult lifespan (GO:0008340)3.37345599
31pore complex assembly (GO:0046931)3.35814333
32DNA strand elongation involved in DNA replication (GO:0006271)3.35734466
33polarized epithelial cell differentiation (GO:0030859)3.32424041
34regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315)3.31248475
35embryonic placenta development (GO:0001892)3.27217931
36positive regulation of Rac GTPase activity (GO:0032855)3.25247981
37regulation of hypersensitivity (GO:0002883)3.25222768
38cellular protein complex localization (GO:0034629)3.23834756
39mitotic nuclear envelope disassembly (GO:0007077)3.22348811
40establishment of monopolar cell polarity (GO:0061162)3.22034289
41establishment or maintenance of monopolar cell polarity (GO:0061339)3.22034289
42nodal signaling pathway (GO:0038092)3.21471269
43morphogenesis of an endothelium (GO:0003159)3.20383787
44endothelial tube morphogenesis (GO:0061154)3.20383787
45DNA strand elongation (GO:0022616)3.16354165
46macrophage differentiation (GO:0030225)3.16286880
47apoptotic cell clearance (GO:0043277)3.15036734
48apoptotic process involved in morphogenesis (GO:0060561)3.13652690
49hyperosmotic salinity response (GO:0042538)3.13337885
50cell-cell junction maintenance (GO:0045217)3.12378184
51regulation of Wnt signaling pathway involved in heart development (GO:0003307)3.11021238
52labyrinthine layer development (GO:0060711)3.09394597
53Notch signaling involved in heart development (GO:0061314)3.09165312
54regulation of apoptotic cell clearance (GO:2000425)3.08150003
55anterior/posterior axis specification, embryo (GO:0008595)3.07996677
56regulation of gene silencing (GO:0060968)3.06526687
57regulation of chemokine secretion (GO:0090196)3.04878042
58semaphorin-plexin signaling pathway (GO:0071526)3.03723217
59membrane disassembly (GO:0030397)3.03184399
60nuclear envelope disassembly (GO:0051081)3.03184399
61L-amino acid import (GO:0043092)3.02347003
62negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.01510503
63vascular endothelial growth factor signaling pathway (GO:0038084)3.00462920
64heart valve formation (GO:0003188)2.94357426
65endothelium development (GO:0003158)2.92659916
66cell migration involved in gastrulation (GO:0042074)2.92211470
67intracellular estrogen receptor signaling pathway (GO:0030520)2.91995827
68regulation of myeloid leukocyte mediated immunity (GO:0002886)2.89763170
69folic acid-containing compound biosynthetic process (GO:0009396)2.87740870
70negative regulation of histone methylation (GO:0031061)2.86251669
71mitotic chromosome condensation (GO:0007076)2.86093322
72mitotic sister chromatid cohesion (GO:0007064)2.85820571
73DNA geometric change (GO:0032392)2.83735160
74negative regulation of androgen receptor signaling pathway (GO:0060766)2.83389222
75embryonic process involved in female pregnancy (GO:0060136)2.83373192
76histone H3-K36 demethylation (GO:0070544)2.83077637
77DNA duplex unwinding (GO:0032508)2.82789669
78glomerular filtration (GO:0003094)2.82685537
79epithelial cell-cell adhesion (GO:0090136)2.80437536
80negative regulation of striated muscle cell differentiation (GO:0051154)2.78534123
81negative regulation of granulocyte differentiation (GO:0030853)2.78505033
82renal filtration (GO:0097205)2.78268610
83protein-DNA complex disassembly (GO:0032986)2.78147173
84nucleosome disassembly (GO:0006337)2.78147173
85phagocytosis, recognition (GO:0006910)2.77769285
86histone H4-K12 acetylation (GO:0043983)2.77676663
87regulation of helicase activity (GO:0051095)2.76981138
88hippo signaling (GO:0035329)2.76491322
89filopodium assembly (GO:0046847)2.74445305
90notochord development (GO:0030903)2.74310434
91regulation of histone H3-K9 methylation (GO:0051570)2.74237189
92lymphangiogenesis (GO:0001946)2.73803723
93lymph vessel development (GO:0001945)2.73798912
94monocyte differentiation (GO:0030224)2.73395808
95DNA replication initiation (GO:0006270)2.70798447
96cardiac muscle adaptation (GO:0014887)2.70398949
97cardiac muscle hypertrophy in response to stress (GO:0014898)2.70398949
98muscle hypertrophy in response to stress (GO:0003299)2.70398949
99adherens junction assembly (GO:0034333)2.69308249
100negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147)2.69147705
101heart trabecula morphogenesis (GO:0061384)2.67769401
102negative regulation of cell size (GO:0045792)2.66834473
103IMP biosynthetic process (GO:0006188)2.66008385
104regulation of mitotic spindle organization (GO:0060236)2.64700432
105somatic diversification of immune receptors via somatic mutation (GO:0002566)2.64073433
106somatic hypermutation of immunoglobulin genes (GO:0016446)2.64073433
107chromatin assembly (GO:0031497)2.63537753
108mitotic sister chromatid segregation (GO:0000070)2.63522455
109ruffle organization (GO:0031529)2.63095290
110telomere maintenance via semi-conservative replication (GO:0032201)2.62765800
111negative regulation of inclusion body assembly (GO:0090084)2.60988806
112peptidyl-arginine omega-N-methylation (GO:0035247)2.60049806
113regulation of sister chromatid cohesion (GO:0007063)2.59774255
114positive regulation of phagocytosis (GO:0050766)2.57840472
115histamine secretion (GO:0001821)2.56693123
116microglial cell activation (GO:0001774)2.54525572
117cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.53410834
118telomere maintenance via recombination (GO:0000722)2.52718798
119vasculogenesis (GO:0001570)2.52108453
120protein localization to chromosome, centromeric region (GO:0071459)2.52057951
121positive regulation of chromosome segregation (GO:0051984)2.51876179
122retina vasculature morphogenesis in camera-type eye (GO:0061299)2.51542985
123I-kappaB phosphorylation (GO:0007252)2.51057114
124L-alpha-amino acid transmembrane transport (GO:1902475)2.50906456
125spliceosomal tri-snRNP complex assembly (GO:0000244)2.50507273
126female genitalia development (GO:0030540)2.50388727
127mitochondrial DNA metabolic process (GO:0032042)2.49917820
128establishment of integrated proviral latency (GO:0075713)2.49885014
129maternal placenta development (GO:0001893)2.49758516
130mitotic G1 DNA damage checkpoint (GO:0031571)2.49487424
131anatomical structure regression (GO:0060033)2.49393682
132vagina development (GO:0060068)2.48870775
133trabecula morphogenesis (GO:0061383)2.48637219
134cell migration involved in sprouting angiogenesis (GO:0002042)2.48606143
135trophectodermal cell differentiation (GO:0001829)2.48552243
136planar cell polarity pathway involved in neural tube closure (GO:0090179)2.48453699
137ventricular trabecula myocardium morphogenesis (GO:0003222)2.47736875
138blood vessel maturation (GO:0001955)2.47673052
139positive regulation of gene expression, epigenetic (GO:0045815)2.47458746
140negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.47382031
141negative regulation of transcription by competitive promoter binding (GO:0010944)2.46799623
142mitotic metaphase plate congression (GO:0007080)2.46689979
143macrophage activation involved in immune response (GO:0002281)2.45738844
144sister chromatid segregation (GO:0000819)2.45490809
145nucleobase biosynthetic process (GO:0046112)2.45181065
146regulation of transcription from RNA polymerase II promoter involved in heart development (GO:1901212.45131266
147regulation of spindle organization (GO:0090224)2.44534504
148regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.42959779
149blood vessel endothelial cell migration (GO:0043534)2.42787062
150cortical actin cytoskeleton organization (GO:0030866)2.42091082
151negative regulation of mRNA processing (GO:0050686)2.41938849
152mitotic G1/S transition checkpoint (GO:0044819)2.41758026
153nuclear envelope organization (GO:0006998)2.40918289
154endothelial cell differentiation (GO:0045446)2.40752699
155regulation of endothelial cell differentiation (GO:0045601)2.40533850
156cell junction maintenance (GO:0034331)2.40317935
157amino acid import (GO:0043090)2.40186813
158negative regulation of gene silencing (GO:0060969)2.39428719
159NLS-bearing protein import into nucleus (GO:0006607)2.38112858
160regulation of telomere maintenance via telomerase (GO:0032210)2.37986000
161cell surface receptor signaling pathway involved in heart development (GO:0061311)2.37628897
162response to laminar fluid shear stress (GO:0034616)2.37605616
163outer ear morphogenesis (GO:0042473)2.37546054
164RNA stabilization (GO:0043489)2.37522847

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.12857756
2KLF5_18264089_ChIP-ChIP_MESCs_Mouse4.24927442
3KLF4_18264089_ChIP-ChIP_MESCs_Mouse4.24927442
4KLF2_18264089_ChIP-ChIP_MESCs_Mouse4.24927442
5FOXM1_23109430_ChIP-Seq_U2OS_Human4.07353317
6EGR1_19374776_ChIP-ChIP_THP-1_Human3.20023041
7POU5F1_18700969_ChIP-ChIP_MESCs_Mouse3.14986849
8NANOG_18700969_ChIP-ChIP_MESCs_Mouse3.04989212
9SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.98314289
10ZIC3_20872845_ChIP-ChIP_MESCs_Mouse2.57747810
11NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.54639369
12TCF3_18692474_ChIP-Seq_MEFs_Mouse2.54561444
13MYC_18555785_ChIP-Seq_MESCs_Mouse2.50309450
14EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.43195754
15SMAD3_22036565_ChIP-Seq_ESCs_Mouse2.38407180
16ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.31780370
17MYC_19079543_ChIP-ChIP_MESCs_Mouse2.30860801
18E2F4_17652178_ChIP-ChIP_JURKAT_Human2.21606418
19LXR_22292898_ChIP-Seq_THP-1_Human2.19033575
20STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.16394312
21STAT3_1855785_ChIP-Seq_MESCs_Mouse2.14257894
22NACC1_18358816_ChIP-ChIP_MESCs_Mouse2.13055633
23TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.08890725
24KDM2B_26808549_Chip-Seq_K562_Human2.05441900
25SOX2_18358816_ChIP-ChIP_MESCs_Mouse2.00151697
26TCF3_18692474_ChIP-Seq_MESCs_Mouse1.99291367
27FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.96821459
28EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.93100353
29CLOCK_20551151_ChIP-Seq_293T_Human1.91587767
30THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.85816407
31SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.85563791
32NANOG_18555785_ChIP-Seq_MESCs_Mouse1.84624490
33SCL_19346495_ChIP-Seq_HPC-7_Human1.84221410
34SOX2_18555785_ChIP-Seq_MESCs_Mouse1.81371865
35PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.78550020
36KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.75433196
37NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.73843914
38ZNF263_19887448_ChIP-Seq_K562_Human1.71089057
39NELFA_20434984_ChIP-Seq_ESCs_Mouse1.70677636
40BP1_19119308_ChIP-ChIP_Hs578T_Human1.62940126
41HIF1A_21447827_ChIP-Seq_MCF-7_Human1.61807138
42MYC_19030024_ChIP-ChIP_MESCs_Mouse1.61742609
43HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.61598628
44MYC_22102868_ChIP-Seq_BL_Human1.61356245
45TP63_17297297_ChIP-ChIP_HaCaT_Human1.59785701
46MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.57214944
47ZFP281_18757296_ChIP-ChIP_E14_Mouse1.56294565
48KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.55208449
49WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.55001000
50VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.54964162
51KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.54696268
52ELK3_25401928_ChIP-Seq_HUVEC_Human1.54309137
53POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.53499910
54NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.53049356
55SALL1_21062744_ChIP-ChIP_HESCs_Human1.51611134
56MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.48153925
57ESR1_15608294_ChIP-ChIP_MCF-7_Human1.46197655
58ERG_21242973_ChIP-ChIP_JURKAT_Human1.45431217
59AR_21909140_ChIP-Seq_LNCAP_Human1.44422789
60SOX2_18692474_ChIP-Seq_MEFs_Mouse1.43980449
61STAT6_21828071_ChIP-Seq_BEAS2B_Human1.42272790
62POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.40773301
63OCT4_18692474_ChIP-Seq_MEFs_Mouse1.40375535
64CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.38238840
65POU5F1_16518401_ChIP-PET_MESCs_Mouse1.36721443
66CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.35463357
67EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.34956263
68KDM2B_26808549_Chip-Seq_JURKAT_Human1.34004374
69VDR_24763502_ChIP-Seq_THP-1_Human1.33196821
70NFIB_24661679_ChIP-Seq_LUNG_Mouse1.33073340
71DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.28954760
72SOX2_18692474_ChIP-Seq_MESCs_Mouse1.28561516
73MYC_18358816_ChIP-ChIP_MESCs_Mouse1.28090126
74NANOG_18692474_ChIP-Seq_MEFs_Mouse1.26012375
75ZFP281_27345836_Chip-Seq_ESCs_Mouse1.25207169
76KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.24936048
77NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.22405535
78E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.22043157
79NANOG_21062744_ChIP-ChIP_HESCs_Human1.21821898
80KLF4_18555785_ChIP-Seq_MESCs_Mouse1.21795624
81UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.21359555
82TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.17236907
83DROSHA_22980978_ChIP-Seq_HELA_Human1.17061758
84XRN2_22483619_ChIP-Seq_HELA_Human1.16609177
85ZFX_18555785_ChIP-Seq_MESCs_Mouse1.16409835
86TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.15032385
87SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.14734930
88NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.14512310
89E2F1_21310950_ChIP-Seq_MCF-7_Human1.13985760
90TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.11947987
91NANOG_18692474_ChIP-Seq_MESCs_Mouse1.11883190
92KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.11035347
93E2F1_18555785_ChIP-Seq_MESCs_Mouse1.10798744
94KDM2B_26808549_Chip-Seq_SUP-B15_Human1.08092291
95RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.07754308
96KDM2B_26808549_Chip-Seq_DND41_Human1.07520969
97MYCN_18555785_ChIP-Seq_MESCs_Mouse1.06314872
98TCF7_22412390_ChIP-Seq_EML_Mouse1.05668510
99RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.05203077
100CTCF_27219007_Chip-Seq_ERYTHROID_Human1.03913841
101CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.03674389
102VDR_21846776_ChIP-Seq_THP-1_Human1.03520988
103POU5F1_18692474_ChIP-Seq_MESCs_Mouse1.03457644
104DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.03424315
105EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.03205717
106ESR1_21235772_ChIP-Seq_MCF-7_Human1.03003940
107CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.02257123
108HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.01001090
109SMC4_20622854_ChIP-Seq_HELA_Human0.99460317
110ATF3_27146783_Chip-Seq_COLON_Human0.99333636
111BRD4_27068464_Chip-Seq_AML-cells_Mouse0.99086065
112KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.98186796
113TBX20_22328084_ChIP-Seq_HEART_Mouse0.98120681
114TBX20_22080862_ChIP-Seq_HEART_Mouse0.98120681
115GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.97383058
116SA1_27219007_Chip-Seq_ERYTHROID_Human0.95801651
117SALL4_18804426_ChIP-ChIP_XEN_Mouse0.95550646
118TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.94365460
119PRDM14_21183938_ChIP-Seq_MESCs_Mouse0.94339039
120TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.93544466
121RARG_19884340_ChIP-ChIP_MEFs_Mouse0.92898085
122RACK7_27058665_Chip-Seq_MCF-7_Human0.92670723
123THAP11_20581084_ChIP-Seq_MESCs_Mouse0.92260954
124EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.92204806
125DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.91534683
126KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.90948950
127TP53_22127205_ChIP-Seq_IMR90_Human0.90864371
128TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.90742735
129TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.89843968
130TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.89797859
131SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.89703974
132P300_27058665_Chip-Seq_ZR-75-30cells_Human0.89329580
133POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.88881923
134TFEB_21752829_ChIP-Seq_HELA_Human0.88304459
135CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.87706965
136SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.87101240
137MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.86897968
138TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.86659883
139KAP1_27257070_Chip-Seq_ESCs_Mouse0.83408558

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003705_abnormal_hypodermis_morpholog3.35318690
2MP0010368_abnormal_lymphatic_system2.73109343
3MP0001661_extended_life_span2.71308794
4MP0004272_abnormal_basement_membrane2.63248444
5MP0005167_abnormal_blood-brain_barrier2.57220044
6MP0003566_abnormal_cell_adhesion2.36652933
7MP0002396_abnormal_hematopoietic_system2.29483738
8MP0010352_gastrointestinal_tract_polyps2.18356560
9MP0009278_abnormal_bone_marrow2.17789694
10MP0003690_abnormal_glial_cell2.16415055
11MP0005076_abnormal_cell_differentiation2.10040895
12MP0003191_abnormal_cellular_cholesterol2.06234012
13MP0005670_abnormal_white_adipose2.02195677
14MP0004185_abnormal_adipocyte_glucose1.98739510
15MP0001986_abnormal_taste_sensitivity1.94882794
16MP0003077_abnormal_cell_cycle1.89858924
17MP0003111_abnormal_nucleus_morphology1.89723677
18MP0004957_abnormal_blastocyst_morpholog1.87805192
19MP0004133_heterotaxia1.84329078
20MP0001730_embryonic_growth_arrest1.83463380
21MP0010094_abnormal_chromosome_stability1.83459483
22MP0001879_abnormal_lymphatic_vessel1.83188789
23MP0004084_abnormal_cardiac_muscle1.80557460
24MP0005380_embryogenesis_phenotype1.77769103
25MP0001672_abnormal_embryogenesis/_devel1.77769103
26MP0005623_abnormal_meninges_morphology1.77117814
27MP0005409_darkened_coat_color1.77104009
28MP0003984_embryonic_growth_retardation1.73957114
29MP0002088_abnormal_embryonic_growth/wei1.73317575
30MP0002086_abnormal_extraembryonic_tissu1.72182776
31MP0008438_abnormal_cutaneous_collagen1.69955437
32MP0003123_paternal_imprinting1.68140230
33MP0008007_abnormal_cellular_replicative1.66527892
34MP0001915_intracranial_hemorrhage1.62819422
35MP0005666_abnormal_adipose_tissue1.61650806
36MP0010030_abnormal_orbit_morphology1.58036539
37MP0002085_abnormal_embryonic_tissue1.54821018
38MP0002653_abnormal_ependyma_morphology1.54523918
39MP0004197_abnormal_fetal_growth/weight/1.53930725
40MP0002084_abnormal_developmental_patter1.52633687
41MP0000350_abnormal_cell_proliferation1.52043471
42MP0010307_abnormal_tumor_latency1.51673914
43MP0003567_abnormal_fetal_cardiomyocyte1.51417970
44MP0002009_preneoplasia1.49274184
45MP0003828_pulmonary_edema1.48037388
46MP0003119_abnormal_digestive_system1.47509407
47MP0003279_aneurysm1.46289977
48MP0001697_abnormal_embryo_size1.45902773
49MP0002925_abnormal_cardiovascular_devel1.43891597
50MP0008057_abnormal_DNA_replication1.42852840
51MP0000767_abnormal_smooth_muscle1.41969025
52MP0009053_abnormal_anal_canal1.38334346
53MP0005023_abnormal_wound_healing1.37297400
54MP0001545_abnormal_hematopoietic_system1.36939764
55MP0005397_hematopoietic_system_phenotyp1.36939764
56MP0010630_abnormal_cardiac_muscle1.34037107
57MP0003283_abnormal_digestive_organ1.32132752
58MP0002332_abnormal_exercise_endurance1.30601782
59MP0006138_congestive_heart_failure1.29357080
60MP0004808_abnormal_hematopoietic_stem1.29244766
61MP0000751_myopathy1.28164069
62MP0003693_abnormal_embryo_hatching1.28053023
63MP0000537_abnormal_urethra_morphology1.23360571
64MP0002254_reproductive_system_inflammat1.23270596
65MP0000465_gastrointestinal_hemorrhage1.23101394
66MP0002080_prenatal_lethality1.20604811
67MP0003890_abnormal_embryonic-extraembry1.20211111
68MP0001849_ear_inflammation1.19233151
69MP0003941_abnormal_skin_development1.17279022
70MP0000750_abnormal_muscle_regeneration1.15673310
71MP0008932_abnormal_embryonic_tissue1.14475372
72MP0003634_abnormal_glial_cell1.14298517
73MP0000733_abnormal_muscle_development1.09817799
74MP0001614_abnormal_blood_vessel1.09663893
75MP0000266_abnormal_heart_morphology1.08400029
76MP0005595_abnormal_vascular_smooth1.08034803
77MP0005375_adipose_tissue_phenotype1.04922001
78MP0009840_abnormal_foam_cell1.02213319
79MP0003121_genomic_imprinting1.00978518
80MP0000249_abnormal_blood_vessel1.00325430
81MP0002269_muscular_atrophy0.99996280
82MP0000343_altered_response_to0.99124277
83MP0002111_abnormal_tail_morphology0.98532116
84MP0005330_cardiomyopathy0.98227992
85MP0002697_abnormal_eye_size0.96591142
86MP0004087_abnormal_muscle_fiber0.96301088
87MP0002127_abnormal_cardiovascular_syste0.94845673
88MP0008058_abnormal_DNA_repair0.94783751
89MP0004036_abnormal_muscle_relaxation0.94490261
90MP0009672_abnormal_birth_weight0.94352241
91MP0000313_abnormal_cell_death0.94122556
92MP0002128_abnormal_blood_circulation0.93911831
93MP0010234_abnormal_vibrissa_follicle0.93082422
94MP0003950_abnormal_plasma_membrane0.91166123
95MP0004782_abnormal_surfactant_physiolog0.90579219
96MP0003806_abnormal_nucleotide_metabolis0.90195612
97MP0008995_early_reproductive_senescence0.90150596
98MP0000003_abnormal_adipose_tissue0.90076973
99MP0002092_abnormal_eye_morphology0.89422469
100MP0001293_anophthalmia0.88946669
101MP0003172_abnormal_lysosome_physiology0.88233697
102MP0003091_abnormal_cell_migration0.86719413
103MP0003303_peritoneal_inflammation0.86126285
104MP0003385_abnormal_body_wall0.85534137
105MP0004130_abnormal_muscle_cell0.85422151
106MP0004742_abnormal_vestibular_system0.84004233
107MP0001544_abnormal_cardiovascular_syste0.83575738
108MP0005385_cardiovascular_system_phenoty0.83575738
109MP0005058_abnormal_lysosome_morphology0.83397037
110MP0005621_abnormal_cell_physiology0.83208317
111MP0003786_premature_aging0.83185040
112MP0003329_amyloid_beta_deposits0.82122455
113MP0000428_abnormal_craniofacial_morphol0.82027052
114MP0002249_abnormal_larynx_morphology0.81901987
115MP0005464_abnormal_platelet_physiology0.80374378
116MP0003115_abnormal_respiratory_system0.80120260
117MP0003935_abnormal_craniofacial_develop0.80060065
118MP0006054_spinal_hemorrhage0.79747088
119MP0004233_abnormal_muscle_weight0.79662052
120MP0000685_abnormal_immune_system0.79228507
121MP0000432_abnormal_head_morphology0.79201458
122MP0002282_abnormal_trachea_morphology0.78850061
123MP0005367_renal/urinary_system_phenotyp0.78824009
124MP0000516_abnormal_urinary_system0.78824009
125MP0009703_decreased_birth_body0.78497957
126MP0008877_abnormal_DNA_methylation0.78418396
127MP0001485_abnormal_pinna_reflex0.76482071
128MP0000747_muscle_weakness0.75901648
129MP0000049_abnormal_middle_ear0.73996156
130MP0002877_abnormal_melanocyte_morpholog0.73158797
131MP0003948_abnormal_gas_homeostasis0.71268082
132MP0002971_abnormal_brown_adipose0.67188855
133MP0001784_abnormal_fluid_regulation0.66713718
134MP0003861_abnormal_nervous_system0.65771954

Predicted human phenotypes

RankGene SetZ-score
1Cerebral aneurysm (HP:0004944)4.96219977
2Ependymoma (HP:0002888)3.89375209
3Systemic lupus erythematosus (HP:0002725)3.49315396
4Hematochezia (HP:0002573)3.42061758
5Agnosia (HP:0010524)3.36492606
6Centrally nucleated skeletal muscle fibers (HP:0003687)3.30305252
7Insomnia (HP:0100785)2.94481095
8Overriding aorta (HP:0002623)2.92596601
9Abnormality of the astrocytes (HP:0100707)2.91009407
10Astrocytoma (HP:0009592)2.91009407
11Elfin facies (HP:0004428)2.83717347
12Rectal fistula (HP:0100590)2.78201638
13Rectovaginal fistula (HP:0000143)2.78201638
14Glomerulonephritis (HP:0000099)2.75885962
15High pitched voice (HP:0001620)2.73269238
16Neoplasm of the oral cavity (HP:0100649)2.71087148
17Colitis (HP:0002583)2.69633820
18Orthostatic hypotension (HP:0001278)2.69295561
19Urethral obstruction (HP:0000796)2.63435870
20Renovascular hypertension (HP:0100817)2.59024079
21Selective tooth agenesis (HP:0001592)2.58267084
22Short humerus (HP:0005792)2.57987703
23Intestinal fistula (HP:0100819)2.56009107
24Turricephaly (HP:0000262)2.53098883
25Shallow orbits (HP:0000586)2.51749169
26Complement deficiency (HP:0004431)2.50394280
27Aplasia/hypoplasia of the humerus (HP:0006507)2.50122813
28Medulloblastoma (HP:0002885)2.48675774
29Abnormality of the lower motor neuron (HP:0002366)2.48296250
30Rib fusion (HP:0000902)2.48098085
31Thickened helices (HP:0000391)2.46192458
32Hand muscle atrophy (HP:0009130)2.45030935
33Skull defect (HP:0001362)2.44855305
34Ankle contracture (HP:0006466)2.43960746
35Vaginal fistula (HP:0004320)2.43731756
36Short 4th metacarpal (HP:0010044)2.43477205
37Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.43477205
38Increased connective tissue (HP:0009025)2.38147690
39Upper motor neuron abnormality (HP:0002127)2.37503227
40Aortic aneurysm (HP:0004942)2.36115062
41Supernumerary ribs (HP:0005815)2.34991082
42Increased nuchal translucency (HP:0010880)2.34570965
43Renal duplication (HP:0000075)2.33125205
44Pseudobulbar signs (HP:0002200)2.32783217
45Spontaneous hematomas (HP:0007420)2.31534840
46Glioma (HP:0009733)2.25911450
47Shawl scrotum (HP:0000049)2.25575330
48Protrusio acetabuli (HP:0003179)2.24616837
49Gastrointestinal carcinoma (HP:0002672)2.22444043
50Malignant gastrointestinal tract tumors (HP:0006749)2.22444043
51Lymphangioma (HP:0100764)2.21309804
52Pointed chin (HP:0000307)2.19910423
53Colon cancer (HP:0003003)2.19467496
54Spinal muscular atrophy (HP:0007269)2.19432887
55Missing ribs (HP:0000921)2.17242108
56Mitral valve prolapse (HP:0001634)2.15646593
57Axonal loss (HP:0003447)2.15147911
58Supernumerary bones of the axial skeleton (HP:0009144)2.14507356
59Metaphyseal cupping (HP:0003021)2.12392908
60Arterial tortuosity (HP:0005116)2.11507832
61Flat cornea (HP:0007720)2.10026608
62Esophageal atresia (HP:0002032)2.09594614
63Abnormality of complement system (HP:0005339)2.08605216
64Upper limb amyotrophy (HP:0009129)2.07868129
65Distal upper limb amyotrophy (HP:0007149)2.07868129
66Disproportionate tall stature (HP:0001519)2.06946022
67Abnormality of the 4th metacarpal (HP:0010012)2.06367560
68Aneurysm (HP:0002617)2.06217732
69Bicuspid aortic valve (HP:0001647)2.06148053
70Wrist flexion contracture (HP:0001239)2.04829645
71Neoplasm of striated muscle (HP:0009728)2.03897438
72High anterior hairline (HP:0009890)2.02433585
73Mutism (HP:0002300)2.01009210
74Agammaglobulinemia (HP:0004432)2.00980399
75Absent toe (HP:0010760)1.99993189
76Dysmetric saccades (HP:0000641)1.99796260
77Premature skin wrinkling (HP:0100678)1.97028721
78Supernumerary spleens (HP:0009799)1.96960446
79Spastic diplegia (HP:0001264)1.96683203
80Arnold-Chiari malformation (HP:0002308)1.94732696
81Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.93994531
82Rhabdomyosarcoma (HP:0002859)1.93442573
83Vertebral fusion (HP:0002948)1.92938660
84Angiofibromas (HP:0010615)1.92473976
85Adenoma sebaceum (HP:0009720)1.92473976
86Abnormality of the fingertips (HP:0001211)1.92342103
87Round ear (HP:0100830)1.92274919
88Gastrointestinal atresia (HP:0002589)1.91770261
89Esophageal varix (HP:0002040)1.91430285
90Progressive external ophthalmoplegia (HP:0000590)1.91053323
91Intestinal polyp (HP:0005266)1.90797900
92Preaxial foot polydactyly (HP:0001841)1.90603172
93Dysphonia (HP:0001618)1.90123459
94Hemangiomatosis (HP:0007461)1.89850360
95Biliary tract neoplasm (HP:0100574)1.89672603
96Adactyly (HP:0009776)1.89301591
97Cortical dysplasia (HP:0002539)1.88538817
98Conjunctival telangiectasia (HP:0000524)1.86862662
99Capillary hemangiomas (HP:0005306)1.85841888
100Diaphragmatic weakness (HP:0009113)1.85258840
101Intestinal atresia (HP:0011100)1.85041611
102Mesangial abnormality (HP:0001966)1.84642024
103Obstructive sleep apnea (HP:0002870)1.84344044
104Vascular tortuosity (HP:0004948)1.84016696
105Aortic dissection (HP:0002647)1.83485100
106Neuronal loss in central nervous system (HP:0002529)1.82731988
107Abnormality of abdominal situs (HP:0011620)1.82411686
108Abdominal situs inversus (HP:0003363)1.82411686
109Difficulty running (HP:0009046)1.82269793
110Fibroma (HP:0010614)1.81952940
111Bladder diverticulum (HP:0000015)1.81583064
112Intestinal polyposis (HP:0200008)1.81254565
113Absent radius (HP:0003974)1.81024398
114Striae distensae (HP:0001065)1.80747873
115Increased variability in muscle fiber diameter (HP:0003557)1.78544095
116Abnormal platelet function (HP:0011869)1.78122732
117Impaired platelet aggregation (HP:0003540)1.78122732
118Deviation of the thumb (HP:0009603)1.77915287
119Abnormality of the salivary glands (HP:0010286)1.76804329
120J-shaped sella turcica (HP:0002680)1.76706155
121Hyperacusis (HP:0010780)1.76288074
122Trigonocephaly (HP:0000243)1.76159809
123Broad thumb (HP:0011304)1.75878137
124Visceral angiomatosis (HP:0100761)1.75301098
125Ventricular tachycardia (HP:0004756)1.75288667
126Megalocornea (HP:0000485)1.75214398
127Nephritis (HP:0000123)1.75154060
128Abnormality of glycosphingolipid metabolism (HP:0004343)1.74958728
129Abnormality of glycolipid metabolism (HP:0010969)1.74958728
130Abnormality of liposaccharide metabolism (HP:0010968)1.74958728
131Abnormality of the labia minora (HP:0012880)1.74073591
132Proximal placement of thumb (HP:0009623)1.73780984
133External ophthalmoplegia (HP:0000544)1.73233828
134Hypoplastic ischia (HP:0003175)1.72851951
135Scanning speech (HP:0002168)1.72799453
136Multiple enchondromatosis (HP:0005701)1.72552398
137Benign neoplasm of the central nervous system (HP:0100835)1.72457224
138Fibrous tissue neoplasm (HP:0012316)1.71838244
139Recurrent cutaneous fungal infections (HP:0011370)1.71827940
140Chronic mucocutaneous candidiasis (HP:0002728)1.71827940
141Short phalanx of the thumb (HP:0009660)1.71599013
142Aplasia involving bones of the extremities (HP:0009825)1.68849876
143Aplasia involving bones of the upper limbs (HP:0009823)1.68849876
144Aplasia of the phalanges of the hand (HP:0009802)1.68849876
145Nonimmune hydrops fetalis (HP:0001790)1.68556824
146Viral hepatitis (HP:0006562)1.68453201
147Exercise-induced myalgia (HP:0003738)1.68408354
148Uterine leiomyosarcoma (HP:0002891)1.68121729
149Leiomyosarcoma (HP:0100243)1.68121729
150Thoracic kyphosis (HP:0002942)1.67832173
151Bronchomalacia (HP:0002780)1.66325027
152Increased cerebral lipofuscin (HP:0011813)1.64593731
153Myopathic facies (HP:0002058)1.64419936
154Abnormality of skeletal muscle fiber size (HP:0012084)1.64174367
155Abnormality of the diencephalon (HP:0010662)1.63968992
156Abnormality of the vasculature of the conjunctiva (HP:0008054)1.62717126
157Cellulitis (HP:0100658)1.61924085
158Short palpebral fissure (HP:0012745)1.61391573
159Obsessive-compulsive behavior (HP:0000722)1.61218326
160Abnormality of the sella turcica (HP:0002679)1.59997075
161Abnormality of cochlea (HP:0000375)1.58915673
162Absent hand (HP:0004050)1.58074087
163Cutis marmorata (HP:0000965)1.57574454
164Aplasia cutis congenita (HP:0001057)1.57134279
165Transitional cell carcinoma of the bladder (HP:0006740)1.56397771

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TGFBR24.60152001
2SMG13.85753871
3CDK123.43652197
4TIE12.92957661
5PAK42.89288341
6PKN22.76433099
7KDR2.68220661
8EPHA22.40757727
9TSSK62.40592013
10MAPK152.37477427
11MAP3K101.98848846
12ICK1.98775357
13TRIB31.97584337
14CDC71.94402189
15WEE11.85895111
16TTN1.81188528
17TTK1.79122513
18CAMK1D1.72221599
19FES1.70811553
20NEK11.68915803
21PNCK1.68792720
22BUB11.68641179
23TGFBR11.67945072
24MAP3K131.65946633
25STK101.58293476
26BLK1.52670512
27PDGFRA1.51821535
28NEK21.50813774
29EEF2K1.45954198
30PDK21.42881642
31PTK61.41789845
32RIPK11.40374229
33TAF11.38505932
34PRPF4B1.38155921
35RPS6KB21.37151539
36LATS21.36652928
37LATS11.33721382
38CDK71.33250557
39CDK61.29028815
40CSF1R1.27792505
41PAK21.24319637
42MAP4K11.20430963
43MTOR1.19746433
44MAP2K31.14667709
45TYRO31.14433345
46PRKD31.13156673
47MAP3K81.11046193
48SCYL21.10664739
49CDK41.10581316
50FLT31.03310547
51ERN11.01172793
52MET0.98164394
53PLK10.91898013
54MAPK120.90449559
55CDC42BPA0.86402001
56MARK20.86032715
57ZAK0.85088216
58ALK0.82497278
59MATK0.81115273
60VRK20.79874460
61VRK10.79812235
62MKNK10.79666602
63MAPKAPK30.76346232
64CAMK1G0.76287772
65STK40.74976241
66STK30.73809434
67BMX0.73435381
68DDR20.72983727
69BRD40.71934949
70NTRK10.71754354
71MAPK70.71574057
72STK38L0.70477103
73BCKDK0.70256789
74MAP3K30.67744520
75MAP2K20.67735860
76JAK30.67604266
77PTK20.66890945
78CSK0.65752292
79GSK3A0.63837144
80NME10.63097073
81FGFR10.62803149
82PLK30.62693234
83GRK70.60249658
84MAP3K70.60152861
85AURKB0.59166492
86ATR0.58166360
87SIK10.58070381
88EPHB20.57886377
89CHEK20.57213719
90CHEK10.57019703
91ROCK20.56205815
92FER0.54772927
93RPS6KA20.54311202
94ITK0.51948874
95TLK10.51054363
96LRRK20.50179282
97MOS0.49459856
98PASK0.49230481
99PTK2B0.48738325
100AURKA0.48506319
101RPS6KA40.48132073
102CDK20.48127724
103ATM0.48036621
104PRKD20.47556104
105PDK40.47262195
106PDK30.47262195
107MAPK100.47043408
108MELK0.46948637
109NTRK20.46750411
110MAPKAPK50.46601452
111CLK10.46022663
112AKT20.45426325
113PIM10.45152343
114FGR0.45125983
115PKN10.44687022
116IRAK30.43528865
117CDK10.42833128
118CDK90.42389096
119MKNK20.41980896
120PRKAA20.41920802
121CAMK40.41072067
122MAP3K110.40288839
123PRKDC0.40219077
124PDGFRB0.39761699
125CDK80.39113437
126GRK10.38425887
127PAK10.38229651
128TESK20.38222553
129NEK90.37546863
130INSR0.37409403
131EPHB10.36370677
132EGFR0.35585604
133RPS6KL10.34429256
134RPS6KC10.34429256
135DMPK0.34054151
136DAPK30.33614418
137PRKG20.32216548
138AKT10.31472102
139GSK3B0.30519343
140RPS6KA60.30423187
141SGK30.30213486
142CDK30.29942604

Predicted pathways (KEGG)

RankGene SetZ-score
1Mismatch repair_Homo sapiens_hsa034302.80007095
2DNA replication_Homo sapiens_hsa030302.61961476
3One carbon pool by folate_Homo sapiens_hsa006702.19476780
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.18588189
5RNA transport_Homo sapiens_hsa030132.18568529
62-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.15312975
7Adherens junction_Homo sapiens_hsa045202.13298778
8Notch signaling pathway_Homo sapiens_hsa043302.05078103
9Spliceosome_Homo sapiens_hsa030402.02021180
10Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.81245131
11Staphylococcus aureus infection_Homo sapiens_hsa051501.80620077
12Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.75272171
13Cell cycle_Homo sapiens_hsa041101.70761892
14Hippo signaling pathway_Homo sapiens_hsa043901.70721219
15Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.68312955
16Basal cell carcinoma_Homo sapiens_hsa052171.63873519
17Glycosaminoglycan degradation_Homo sapiens_hsa005311.62351380
18TGF-beta signaling pathway_Homo sapiens_hsa043501.59875471
19Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.59551340
20Nitrogen metabolism_Homo sapiens_hsa009101.50333063
21Prion diseases_Homo sapiens_hsa050201.49731112
22Focal adhesion_Homo sapiens_hsa045101.41975482
23Non-homologous end-joining_Homo sapiens_hsa034501.38960268
24Phospholipase D signaling pathway_Homo sapiens_hsa040721.37552929
25ECM-receptor interaction_Homo sapiens_hsa045121.35776150
26mRNA surveillance pathway_Homo sapiens_hsa030151.35743422
27Small cell lung cancer_Homo sapiens_hsa052221.34149518
28B cell receptor signaling pathway_Homo sapiens_hsa046621.32704882
29MicroRNAs in cancer_Homo sapiens_hsa052061.31273469
30Base excision repair_Homo sapiens_hsa034101.25210699
31Biosynthesis of amino acids_Homo sapiens_hsa012301.25173573
32Lysine degradation_Homo sapiens_hsa003101.25090377
33Other glycan degradation_Homo sapiens_hsa005111.23131273
34Tight junction_Homo sapiens_hsa045301.19211483
35Hedgehog signaling pathway_Homo sapiens_hsa043401.18947073
36Systemic lupus erythematosus_Homo sapiens_hsa053221.18272713
37Nucleotide excision repair_Homo sapiens_hsa034201.16776304
38Alcoholism_Homo sapiens_hsa050341.14613219
39Colorectal cancer_Homo sapiens_hsa052101.14347008
40Proteoglycans in cancer_Homo sapiens_hsa052051.13126080
41Central carbon metabolism in cancer_Homo sapiens_hsa052301.10203118
42Glioma_Homo sapiens_hsa052141.10196154
43Carbon metabolism_Homo sapiens_hsa012001.10071316
44Viral myocarditis_Homo sapiens_hsa054161.09567098
45Leukocyte transendothelial migration_Homo sapiens_hsa046701.08001354
46p53 signaling pathway_Homo sapiens_hsa041151.06923277
47Complement and coagulation cascades_Homo sapiens_hsa046101.06504066
48HTLV-I infection_Homo sapiens_hsa051661.06370975
49Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.05749463
50Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.05172331
51Homologous recombination_Homo sapiens_hsa034401.04142155
52Platelet activation_Homo sapiens_hsa046111.00575699
53Vitamin B6 metabolism_Homo sapiens_hsa007500.99414461
54Pathways in cancer_Homo sapiens_hsa052000.98784496
55Antigen processing and presentation_Homo sapiens_hsa046120.98243098
56mTOR signaling pathway_Homo sapiens_hsa041500.97937359
57Viral carcinogenesis_Homo sapiens_hsa052030.96715427
58AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.95535541
59Chronic myeloid leukemia_Homo sapiens_hsa052200.95312859
60GnRH signaling pathway_Homo sapiens_hsa049120.93143545
61Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.92645813
62Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.91821210
63Pentose phosphate pathway_Homo sapiens_hsa000300.90413375
64Selenocompound metabolism_Homo sapiens_hsa004500.89955405
65Legionellosis_Homo sapiens_hsa051340.89098487
66Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.87692846
67cGMP-PKG signaling pathway_Homo sapiens_hsa040220.85277171
68HIF-1 signaling pathway_Homo sapiens_hsa040660.85212151
69Long-term potentiation_Homo sapiens_hsa047200.84225642
70Gastric acid secretion_Homo sapiens_hsa049710.83241485
71Rap1 signaling pathway_Homo sapiens_hsa040150.82842062
72Fatty acid degradation_Homo sapiens_hsa000710.81977097
73Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.81438164
74Long-term depression_Homo sapiens_hsa047300.81270720
75Regulation of actin cytoskeleton_Homo sapiens_hsa048100.80785645
76Gap junction_Homo sapiens_hsa045400.80433897
77Inositol phosphate metabolism_Homo sapiens_hsa005620.80234797
78Fatty acid metabolism_Homo sapiens_hsa012120.80171185
79Dilated cardiomyopathy_Homo sapiens_hsa054140.79703556
80Pertussis_Homo sapiens_hsa051330.79445180
81Leishmaniasis_Homo sapiens_hsa051400.79045728
82Neurotrophin signaling pathway_Homo sapiens_hsa047220.78266921
83Lysosome_Homo sapiens_hsa041420.78075916
84Acute myeloid leukemia_Homo sapiens_hsa052210.77697527
85Transcriptional misregulation in cancer_Homo sapiens_hsa052020.77344261
86Non-small cell lung cancer_Homo sapiens_hsa052230.76555832
87Bladder cancer_Homo sapiens_hsa052190.75367691
88Fanconi anemia pathway_Homo sapiens_hsa034600.74740874
89Thyroid cancer_Homo sapiens_hsa052160.74407174
90Melanogenesis_Homo sapiens_hsa049160.74061655
91Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.73565014
92Fatty acid biosynthesis_Homo sapiens_hsa000610.73219943
93PI3K-Akt signaling pathway_Homo sapiens_hsa041510.72975347
94Aldosterone synthesis and secretion_Homo sapiens_hsa049250.72628851
95Carbohydrate digestion and absorption_Homo sapiens_hsa049730.72525780
96Amoebiasis_Homo sapiens_hsa051460.72498660
97Renal cell carcinoma_Homo sapiens_hsa052110.72000552
98Phosphatidylinositol signaling system_Homo sapiens_hsa040700.71887745
99VEGF signaling pathway_Homo sapiens_hsa043700.70906576
100Dorso-ventral axis formation_Homo sapiens_hsa043200.70826485
101Axon guidance_Homo sapiens_hsa043600.70596792
102Sphingolipid signaling pathway_Homo sapiens_hsa040710.69463915
103Wnt signaling pathway_Homo sapiens_hsa043100.69403142
104Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.69208296
105PPAR signaling pathway_Homo sapiens_hsa033200.69020671
106Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.68725042
107Arginine biosynthesis_Homo sapiens_hsa002200.67774027
108Insulin resistance_Homo sapiens_hsa049310.67211551
109Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.65376061
110Epstein-Barr virus infection_Homo sapiens_hsa051690.65153367
111Endometrial cancer_Homo sapiens_hsa052130.63022675
112Oocyte meiosis_Homo sapiens_hsa041140.62399935
113Toxoplasmosis_Homo sapiens_hsa051450.62295677
114Apoptosis_Homo sapiens_hsa042100.61546810
115Renin secretion_Homo sapiens_hsa049240.59803561
116Oxytocin signaling pathway_Homo sapiens_hsa049210.59048451
117Thyroid hormone signaling pathway_Homo sapiens_hsa049190.57533017
118Galactose metabolism_Homo sapiens_hsa000520.56836635
119RNA degradation_Homo sapiens_hsa030180.56512766
120Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.56276244
121AMPK signaling pathway_Homo sapiens_hsa041520.56045762
122Insulin signaling pathway_Homo sapiens_hsa049100.54011128
123Sulfur relay system_Homo sapiens_hsa041220.53658160
124Pancreatic cancer_Homo sapiens_hsa052120.53423763
125Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.53314906
126Choline metabolism in cancer_Homo sapiens_hsa052310.53095128
127Estrogen signaling pathway_Homo sapiens_hsa049150.52755945
128Melanoma_Homo sapiens_hsa052180.51608704
129Thyroid hormone synthesis_Homo sapiens_hsa049180.51405806
130Propanoate metabolism_Homo sapiens_hsa006400.50767763
131Prostate cancer_Homo sapiens_hsa052150.48282097
132Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.46851693
133Osteoclast differentiation_Homo sapiens_hsa043800.46058397
134Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.45793589
135Ribosome_Homo sapiens_hsa030100.45335765
136Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.45005934
137Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.44115350
138Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.42615690
139Longevity regulating pathway - mammal_Homo sapiens_hsa042110.42206086

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