PALM2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neuron cell-cell adhesion (GO:0007158)5.31072377
2vocalization behavior (GO:0071625)4.97990825
3pyrimidine nucleobase catabolic process (GO:0006208)4.82367264
4regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.77995887
5glutamate secretion (GO:0014047)4.56768958
6synaptic vesicle exocytosis (GO:0016079)4.55948630
7regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.45032047
8synaptic vesicle docking involved in exocytosis (GO:0016081)4.40525897
9presynaptic membrane assembly (GO:0097105)4.32557037
10positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.32542952
11protein localization to synapse (GO:0035418)4.32176522
12locomotory exploration behavior (GO:0035641)4.31608862
13regulation of glutamate receptor signaling pathway (GO:1900449)4.30532773
14regulation of short-term neuronal synaptic plasticity (GO:0048172)4.22535225
15nucleobase catabolic process (GO:0046113)4.22513199
16dopamine biosynthetic process (GO:0042416)4.21598255
17regulation of synaptic vesicle exocytosis (GO:2000300)4.05108746
18presynaptic membrane organization (GO:0097090)4.00223578
19ionotropic glutamate receptor signaling pathway (GO:0035235)3.92138958
20postsynaptic membrane organization (GO:0001941)3.92081064
21primary amino compound metabolic process (GO:1901160)3.89996546
22neurotransmitter-gated ion channel clustering (GO:0072578)3.84491466
23glutamate receptor signaling pathway (GO:0007215)3.82131592
24positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.70940406
25synaptic vesicle maturation (GO:0016188)3.65082942
26exploration behavior (GO:0035640)3.64826959
27behavioral response to nicotine (GO:0035095)3.60231265
28neuronal action potential (GO:0019228)3.59142653
29synaptic transmission, glutamatergic (GO:0035249)3.58883716
30negative regulation of synaptic transmission, GABAergic (GO:0032229)3.58454419
31membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.56932472
32regulation of hexokinase activity (GO:1903299)3.56822478
33regulation of glucokinase activity (GO:0033131)3.56822478
34neuron-neuron synaptic transmission (GO:0007270)3.54083777
35regulation of synaptic vesicle transport (GO:1902803)3.46807297
36axonal fasciculation (GO:0007413)3.46567011
37G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.44927247
38regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.43885818
39neuron recognition (GO:0008038)3.43351341
40negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.38212798
41cerebellar granule cell differentiation (GO:0021707)3.37342582
42cellular ketone body metabolic process (GO:0046950)3.36180766
43proline transport (GO:0015824)3.33441966
44gamma-aminobutyric acid signaling pathway (GO:0007214)3.27999395
45regulation of excitatory postsynaptic membrane potential (GO:0060079)3.27886059
46regulation of synaptic transmission, glutamatergic (GO:0051966)3.23193699
47neurotransmitter secretion (GO:0007269)3.20962514
48neuronal action potential propagation (GO:0019227)3.16213997
49startle response (GO:0001964)3.15771832
50membrane depolarization during action potential (GO:0086010)3.15180620
51negative regulation of dendrite morphogenesis (GO:0050774)3.14476472
52regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.13735587
53regulation of postsynaptic membrane potential (GO:0060078)3.13339748
54dendritic spine morphogenesis (GO:0060997)3.09793013
55positive regulation of synapse assembly (GO:0051965)3.09744206
56transmission of nerve impulse (GO:0019226)3.05067079
57adaptation of signaling pathway (GO:0023058)3.04472058
58regulation of long-term neuronal synaptic plasticity (GO:0048169)3.03357368
59positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.02728405
60long-term synaptic potentiation (GO:0060291)3.01496639
61response to histamine (GO:0034776)3.00100099
62regulation of neuronal synaptic plasticity (GO:0048168)2.99542329
63regulation of neurotransmitter secretion (GO:0046928)2.98418908
64glycerophospholipid catabolic process (GO:0046475)2.97532816
65serotonin metabolic process (GO:0042428)2.97131045
66regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.97121900
67ketone body metabolic process (GO:1902224)2.96199576
68indole-containing compound metabolic process (GO:0042430)2.95790887
69catechol-containing compound biosynthetic process (GO:0009713)2.95087497
70catecholamine biosynthetic process (GO:0042423)2.95087497
71synapse assembly (GO:0007416)2.93977862
72membrane depolarization (GO:0051899)2.93694784
73regulation of cell communication by electrical coupling (GO:0010649)2.93337766
74cerebellar Purkinje cell differentiation (GO:0021702)2.93173414
75regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO2.92842498
76positive regulation of synapse maturation (GO:0090129)2.91246767
77detection of calcium ion (GO:0005513)2.89978929
78regulation of synaptic plasticity (GO:0048167)2.88997050
79synaptic vesicle endocytosis (GO:0048488)2.88971824
80positive regulation of synaptic transmission, GABAergic (GO:0032230)2.88448842
81gamma-aminobutyric acid transport (GO:0015812)2.86989860
82negative regulation of dendrite development (GO:2000171)2.86552464
83dendrite morphogenesis (GO:0048813)2.86327190
84regulation of synapse assembly (GO:0051963)2.85880077
85positive regulation of cardiac muscle cell differentiation (GO:2000727)2.85551003
86membrane assembly (GO:0071709)2.83916808
87long-term memory (GO:0007616)2.83428448
88behavioral response to cocaine (GO:0048148)2.82939232
89positive regulation of membrane potential (GO:0045838)2.82489380
90cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.81923927
91negative regulation of cytosolic calcium ion concentration (GO:0051481)2.80786292
92urinary tract smooth muscle contraction (GO:0014848)2.80197450
93action potential (GO:0001508)2.79451348
94regulation of dendritic spine morphogenesis (GO:0061001)2.79049946
95positive regulation of neurotransmitter secretion (GO:0001956)2.76643828
96regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)2.75776703
97positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.75316987
98learning (GO:0007612)2.73949638
99auditory behavior (GO:0031223)2.71018281
100dendrite development (GO:0016358)2.70924377
101positive regulation of muscle hypertrophy (GO:0014742)2.70822968
102positive regulation of cardiac muscle hypertrophy (GO:0010613)2.70822968
103calcium ion-dependent exocytosis (GO:0017156)2.70608866
104regulation of vesicle fusion (GO:0031338)2.70239840
105neurotransmitter transport (GO:0006836)2.70232128
106C4-dicarboxylate transport (GO:0015740)2.70025026
107regulation of neurotransmitter transport (GO:0051588)2.69885783
108behavioral fear response (GO:0001662)2.69257081
109behavioral defense response (GO:0002209)2.69257081
110regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.69240364
111cell communication involved in cardiac conduction (GO:0086065)2.68902769
112positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.68896314
113vascular smooth muscle contraction (GO:0014829)2.67764859
114regulation of dendritic spine development (GO:0060998)2.67270398
115positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.67255993
116central nervous system projection neuron axonogenesis (GO:0021952)2.66967326
117regulation of voltage-gated calcium channel activity (GO:1901385)2.66786431
118synaptic transmission (GO:0007268)2.66343391
119acrosome reaction (GO:0007340)2.66028126
120regulation of glutamate secretion (GO:0014048)2.64522902
121synapse organization (GO:0050808)2.63874096
122negative regulation of neurotransmitter transport (GO:0051589)2.63461502
123regulation of synaptic transmission, GABAergic (GO:0032228)2.63066346
124glycosphingolipid biosynthetic process (GO:0006688)2.62633151
125water-soluble vitamin biosynthetic process (GO:0042364)2.62073933
126righting reflex (GO:0060013)2.54060199
127indolalkylamine metabolic process (GO:0006586)2.54031211
128regulation of dopamine metabolic process (GO:0042053)2.51589865
129regulation of catecholamine metabolic process (GO:0042069)2.51589865
130nerve growth factor signaling pathway (GO:0038180)2.50537777
131positive regulation of protein depolymerization (GO:1901881)2.48286707
132fear response (GO:0042596)2.46047212
133phosphorelay signal transduction system (GO:0000160)2.43542008
134negative regulation of hormone biosynthetic process (GO:0032353)2.43497134
135neuron maturation (GO:0042551)2.40726350
136short-term memory (GO:0007614)2.40613007
137positive regulation of potassium ion transmembrane transport (GO:1901381)2.39931686
138atrial cardiac muscle cell action potential (GO:0086014)2.39338029
139dopamine transport (GO:0015872)2.38925414
140regulation of calcium ion-dependent exocytosis (GO:0017158)2.38215675
141regulation of synapse structural plasticity (GO:0051823)2.36913789
142serotonin receptor signaling pathway (GO:0007210)2.35923551
143regulation of action potential (GO:0098900)2.34535798
144brain morphogenesis (GO:0048854)2.34288397
145microtubule severing (GO:0051013)2.33505323
146regulation of sarcomere organization (GO:0060297)2.30823987
147macroautophagy (GO:0016236)2.30466362
148regulation of membrane repolarization (GO:0060306)2.30007910
149neurofilament cytoskeleton organization (GO:0060052)2.26838703
150response to amphetamine (GO:0001975)2.26651326

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.47377300
2GBX2_23144817_ChIP-Seq_PC3_Human4.25932032
3* SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.92221421
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.85107954
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.84020381
6SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.52418773
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.50464857
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.50464857
9EZH2_27304074_Chip-Seq_ESCs_Mouse2.49626491
10GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.47861154
11SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.43960821
12EED_16625203_ChIP-ChIP_MESCs_Mouse2.42314474
13JARID2_20075857_ChIP-Seq_MESCs_Mouse2.36860926
14SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.35541791
15TAF15_26573619_Chip-Seq_HEK293_Human2.30738483
16RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.18697652
17* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.14876070
18CTBP2_25329375_ChIP-Seq_LNCAP_Human2.07782249
19ZFP57_27257070_Chip-Seq_ESCs_Mouse2.07361441
20* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.05338094
21REST_21632747_ChIP-Seq_MESCs_Mouse2.01876265
22RNF2_27304074_Chip-Seq_ESCs_Mouse2.00967125
23* SMAD4_21799915_ChIP-Seq_A2780_Human1.93462603
24P300_19829295_ChIP-Seq_ESCs_Human1.93162203
25DROSHA_22980978_ChIP-Seq_HELA_Human1.91488405
26PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.90470190
27EZH2_27294783_Chip-Seq_ESCs_Mouse1.88675603
28SUZ12_27294783_Chip-Seq_ESCs_Mouse1.83899393
29CTBP1_25329375_ChIP-Seq_LNCAP_Human1.83121705
30SMAD_19615063_ChIP-ChIP_OVARY_Human1.81443440
31ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.81084719
32AR_21572438_ChIP-Seq_LNCaP_Human1.80085016
33* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.77380766
34FLI1_27457419_Chip-Seq_LIVER_Mouse1.75528020
35SALL1_21062744_ChIP-ChIP_HESCs_Human1.73619945
36POU3F2_20337985_ChIP-ChIP_501MEL_Human1.72553138
37BMI1_23680149_ChIP-Seq_NPCS_Mouse1.72497334
38CBX2_27304074_Chip-Seq_ESCs_Mouse1.69412001
39CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.63981272
40TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.60634165
41SMAD3_21741376_ChIP-Seq_EPCs_Human1.59892769
42GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.59755188
43PIAS1_25552417_ChIP-Seq_VCAP_Human1.59128181
44OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.58535899
45PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.57406269
46NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.57333097
47SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.57039806
48RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.55929804
49SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.55408987
50TOP2B_26459242_ChIP-Seq_MCF-7_Human1.54099401
51RARB_27405468_Chip-Seq_BRAIN_Mouse1.52144884
52FUS_26573619_Chip-Seq_HEK293_Human1.51151718
53FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.48539407
54CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.46927773
55REST_18959480_ChIP-ChIP_MESCs_Mouse1.46799336
56AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.45792955
57PCGF2_27294783_Chip-Seq_ESCs_Mouse1.43432868
58CBP_20019798_ChIP-Seq_JUKART_Human1.43352705
59IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.43352705
60RNF2_27304074_Chip-Seq_NSC_Mouse1.40469294
61CDX2_19796622_ChIP-Seq_MESCs_Mouse1.40385687
62AR_25329375_ChIP-Seq_VCAP_Human1.38728652
63* STAT3_23295773_ChIP-Seq_U87_Human1.37505275
64NR3C1_23031785_ChIP-Seq_PC12_Mouse1.37363259
65BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.37154169
66* SOX2_21211035_ChIP-Seq_LN229_Gbm1.34879641
67* EP300_21415370_ChIP-Seq_HL-1_Mouse1.34199116
68VDR_22108803_ChIP-Seq_LS180_Human1.32828619
69TCF4_23295773_ChIP-Seq_U87_Human1.28162308
70TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.28021064
71SUZ12_27294783_Chip-Seq_NPCs_Mouse1.27800097
72TP53_18474530_ChIP-ChIP_U2OS_Human1.26338371
73* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.25198554
74ZNF217_24962896_ChIP-Seq_MCF-7_Human1.24600352
75* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.24063135
76ER_23166858_ChIP-Seq_MCF-7_Human1.22698775
77IKZF1_21737484_ChIP-ChIP_HCT116_Human1.22595111
78UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.21675237
79ARNT_22903824_ChIP-Seq_MCF-7_Human1.21487114
80EZH2_27294783_Chip-Seq_NPCs_Mouse1.21176140
81CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.20500845
82KLF5_20875108_ChIP-Seq_MESCs_Mouse1.20345987
83* NANOG_18555785_Chip-Seq_ESCs_Mouse1.20274929
84RUNX2_22187159_ChIP-Seq_PCA_Human1.19609124
85AHR_22903824_ChIP-Seq_MCF-7_Human1.19606190
86NFE2_27457419_Chip-Seq_LIVER_Mouse1.18046730
87JUN_21703547_ChIP-Seq_K562_Human1.15655038
88AR_19668381_ChIP-Seq_PC3_Human1.15109305
89RBPJ_22232070_ChIP-Seq_NCS_Mouse1.15080353
90IGF1R_20145208_ChIP-Seq_DFB_Human1.14046888
91E2F1_18555785_Chip-Seq_ESCs_Mouse1.13720379
92POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.12931505
93TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12931505
94* ZNF274_21170338_ChIP-Seq_K562_Hela1.12914182
95PRDM14_20953172_ChIP-Seq_ESCs_Human1.12412137
96* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.12391035
97TAL1_26923725_Chip-Seq_HPCs_Mouse1.12289688
98FLI1_21867929_ChIP-Seq_TH2_Mouse1.11791234
99NR3C1_21868756_ChIP-Seq_MCF10A_Human1.11275899
100TCF4_22108803_ChIP-Seq_LS180_Human1.11113765
101RING1B_27294783_Chip-Seq_ESCs_Mouse1.09741063
102YAP1_20516196_ChIP-Seq_MESCs_Mouse1.09055455
103KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.09020811
104TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08568622
105TP53_16413492_ChIP-PET_HCT116_Human1.07203910
106BCAT_22108803_ChIP-Seq_LS180_Human1.06957596
107SUZ12_18555785_Chip-Seq_ESCs_Mouse1.05965760
108RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.05720649
109HTT_18923047_ChIP-ChIP_STHdh_Human1.05473752
110MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.05063252
111P53_22127205_ChIP-Seq_FIBROBLAST_Human1.04780643
112P53_22387025_ChIP-Seq_ESCs_Mouse1.04574809
113SMAD4_21741376_ChIP-Seq_EPCs_Human1.04170031
114STAT3_18555785_Chip-Seq_ESCs_Mouse1.03337130
115CMYC_18555785_Chip-Seq_ESCs_Mouse1.02943662
116* SOX9_26525672_Chip-Seq_HEART_Mouse1.01663351
117MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.01206942
118CRX_20693478_ChIP-Seq_RETINA_Mouse1.01146415
119EWS_26573619_Chip-Seq_HEK293_Human0.99971878
120LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99230489
121TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.97806857
122RXR_22108803_ChIP-Seq_LS180_Human0.97694250
123SMAD4_21741376_ChIP-Seq_HESCs_Human0.97229338

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.79313408
2MP0003880_abnormal_central_pattern4.48077350
3MP0001968_abnormal_touch/_nociception3.65680394
4MP0004270_analgesia3.46908321
5MP0003635_abnormal_synaptic_transmissio3.40733197
6MP0002735_abnormal_chemical_nociception3.14495881
7MP0002736_abnormal_nociception_after3.11892756
8MP0009745_abnormal_behavioral_response3.03031972
9MP0009046_muscle_twitch2.85685897
10MP0002063_abnormal_learning/memory/cond2.81087635
11MP0002734_abnormal_mechanical_nocicepti2.77324161
12MP0002064_seizures2.74856097
13MP0002572_abnormal_emotion/affect_behav2.64078992
14MP0008877_abnormal_DNA_methylation2.57041523
15MP0003122_maternal_imprinting2.46031147
16MP0002272_abnormal_nervous_system2.38626106
17MP0006276_abnormal_autonomic_nervous2.37197531
18MP0001486_abnormal_startle_reflex2.23770284
19MP0002733_abnormal_thermal_nociception2.20196030
20MP0005423_abnormal_somatic_nervous2.06556907
21MP0003195_calcinosis2.05021512
22MP0003787_abnormal_imprinting2.01204113
23MP0001970_abnormal_pain_threshold2.00950653
24MP0001440_abnormal_grooming_behavior1.98051795
25MP0002067_abnormal_sensory_capabilities1.96552182
26MP0001501_abnormal_sleep_pattern1.95251266
27MP0000778_abnormal_nervous_system1.94113360
28MP0002184_abnormal_innervation1.89325595
29MP0009780_abnormal_chondrocyte_physiolo1.87795855
30MP0003283_abnormal_digestive_organ1.76133748
31MP0002557_abnormal_social/conspecific_i1.68308798
32MP0001984_abnormal_olfaction1.59965536
33MP0005386_behavior/neurological_phenoty1.58861505
34MP0004924_abnormal_behavior1.58861505
35MP0005646_abnormal_pituitary_gland1.58423395
36MP0005187_abnormal_penis_morphology1.56678388
37MP0005645_abnormal_hypothalamus_physiol1.55962812
38MP0001529_abnormal_vocalization1.51366818
39MP0005171_absent_coat_pigmentation1.50472069
40MP0004145_abnormal_muscle_electrophysio1.49084718
41MP0000751_myopathy1.47744930
42MP0003879_abnormal_hair_cell1.45223673
43MP0001188_hyperpigmentation1.35965668
44MP0002638_abnormal_pupillary_reflex1.34561207
45MP0001905_abnormal_dopamine_level1.33784450
46MP0004215_abnormal_myocardial_fiber1.33314572
47MP0002837_dystrophic_cardiac_calcinosis1.32931890
48MP0004085_abnormal_heartbeat1.31744045
49MP0004811_abnormal_neuron_physiology1.31110767
50MP0004858_abnormal_nervous_system1.30756819
51MP0003950_abnormal_plasma_membrane1.30020726
52MP0002882_abnormal_neuron_morphology1.26137230
53MP0008569_lethality_at_weaning1.25578322
54MP0004742_abnormal_vestibular_system1.24262853
55MP0000749_muscle_degeneration1.23403138
56MP0000955_abnormal_spinal_cord1.22061276
57MP0003121_genomic_imprinting1.20224019
58MP0004043_abnormal_pH_regulation1.18285345
59MP0002066_abnormal_motor_capabilities/c1.18025373
60MP0004084_abnormal_cardiac_muscle1.16851407
61MP0000013_abnormal_adipose_tissue1.15540630
62MP0004142_abnormal_muscle_tone1.14330456
63MP0002938_white_spotting1.10031067
64MP0009697_abnormal_copulation1.07683594
65MP0001502_abnormal_circadian_rhythm1.06329527
66MP0003137_abnormal_impulse_conducting1.05671242
67MP0002822_catalepsy1.04233770
68MP0004484_altered_response_of1.03752530
69MP0006072_abnormal_retinal_apoptosis1.02859241
70MP0001299_abnormal_eye_distance/1.02780083
71MP0002972_abnormal_cardiac_muscle1.02178492
72MP0004036_abnormal_muscle_relaxation1.00663299
73MP0004510_myositis1.00358812
74MP0003890_abnormal_embryonic-extraembry0.99450981
75MP0005253_abnormal_eye_physiology0.97784526
76MP0005620_abnormal_muscle_contractility0.95299443
77MP0001963_abnormal_hearing_physiology0.94440680
78MP0002139_abnormal_hepatobiliary_system0.94123015
79MP0002152_abnormal_brain_morphology0.93036972
80MP0003633_abnormal_nervous_system0.89639735
81MP0000569_abnormal_digit_pigmentation0.87212640
82MP0008775_abnormal_heart_ventricle0.86376625
83MP0001485_abnormal_pinna_reflex0.86308806
84MP0003329_amyloid_beta_deposits0.83813937
85MP0000427_abnormal_hair_cycle0.80743973
86MP0004133_heterotaxia0.79695767
87MP0010386_abnormal_urinary_bladder0.78077248
88MP0003631_nervous_system_phenotype0.77830739
89MP0002876_abnormal_thyroid_physiology0.77659232
90MP0003123_paternal_imprinting0.77006966
91MP0005503_abnormal_tendon_morphology0.76998288
92MP0000631_abnormal_neuroendocrine_gland0.76920699
93MP0001944_abnormal_pancreas_morphology0.76868988
94MP0002752_abnormal_somatic_nervous0.76336312
95MP0003937_abnormal_limbs/digits/tail_de0.74439512
96MP0002102_abnormal_ear_morphology0.72944901
97MP0002751_abnormal_autonomic_nervous0.72932800
98MP0006138_congestive_heart_failure0.71400315
99MP0001177_atelectasis0.70604117
100MP0003011_delayed_dark_adaptation0.69552015
101MP0000462_abnormal_digestive_system0.69381148
102MP0000230_abnormal_systemic_arterial0.68470063
103MP0005623_abnormal_meninges_morphology0.68461246
104MP0005330_cardiomyopathy0.68072137
105MP0003634_abnormal_glial_cell0.67782982
106MP0002069_abnormal_eating/drinking_beha0.67598223
107MP0004885_abnormal_endolymph0.67591275
108MP0003119_abnormal_digestive_system0.67253518
109MP0000920_abnormal_myelination0.66837218
110MP0005195_abnormal_posterior_eye0.65673386
111MP0003632_abnormal_nervous_system0.65272837
112MP0005551_abnormal_eye_electrophysiolog0.63697237
113MP0008874_decreased_physiological_sensi0.63187092
114MP0002229_neurodegeneration0.62931821
115MP0000026_abnormal_inner_ear0.62892829
116MP0002127_abnormal_cardiovascular_syste0.62860174
117MP0001986_abnormal_taste_sensitivity0.62181536
118MP0001664_abnormal_digestion0.62057155
119MP0002909_abnormal_adrenal_gland0.61165780
120MP0009250_abnormal_appendicular_skeleto0.57215853
121MP0003385_abnormal_body_wall0.56506827
122MP0001943_abnormal_respiration0.56190692
123MP0005535_abnormal_body_temperature0.55526390

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.63215923
2Epileptic encephalopathy (HP:0200134)5.06271622
3Focal seizures (HP:0007359)4.99024650
4Myokymia (HP:0002411)4.78125932
5Atonic seizures (HP:0010819)4.55204404
6Hyperventilation (HP:0002883)4.38784810
7Febrile seizures (HP:0002373)4.38260978
8Progressive cerebellar ataxia (HP:0002073)3.92798519
9Broad-based gait (HP:0002136)3.62782520
10Visual hallucinations (HP:0002367)3.38444485
11Absence seizures (HP:0002121)3.36640080
12Generalized tonic-clonic seizures (HP:0002069)3.34490396
13Dialeptic seizures (HP:0011146)3.30363250
14Limb dystonia (HP:0002451)3.14509855
15Pheochromocytoma (HP:0002666)3.06942549
16Ketoacidosis (HP:0001993)3.02156124
17Poor suck (HP:0002033)3.02115054
18Large for gestational age (HP:0001520)2.93125249
19Gaze-evoked nystagmus (HP:0000640)2.86488874
20Fetal akinesia sequence (HP:0001989)2.72139110
21Hemiparesis (HP:0001269)2.69098275
22Sudden death (HP:0001699)2.67798553
23Amblyopia (HP:0000646)2.66096067
24Hyperinsulinemic hypoglycemia (HP:0000825)2.65364010
25Drooling (HP:0002307)2.62425081
26Excessive salivation (HP:0003781)2.62425081
27Aplasia of the musculature (HP:0100854)2.54213575
28Action tremor (HP:0002345)2.53945434
29Absent speech (HP:0001344)2.52868895
30Termporal pattern (HP:0011008)2.52081811
31Insidious onset (HP:0003587)2.52081811
32Neuroendocrine neoplasm (HP:0100634)2.51721100
33Hypoglycemic seizures (HP:0002173)2.51071161
34Atrial fibrillation (HP:0005110)2.46215137
35Gait imbalance (HP:0002141)2.45752556
36Primary atrial arrhythmia (HP:0001692)2.45330255
37Impaired vibration sensation in the lower limbs (HP:0002166)2.44671895
38Progressive macrocephaly (HP:0004481)2.44155161
39Hypoglycemic coma (HP:0001325)2.43519411
40Absent/shortened dynein arms (HP:0200106)2.43119334
41Dynein arm defect of respiratory motile cilia (HP:0012255)2.43119334
42Abnormal hair whorl (HP:0010721)2.42518204
43Urinary bladder sphincter dysfunction (HP:0002839)2.42209493
44Akinesia (HP:0002304)2.40824419
45Acute necrotizing encephalopathy (HP:0006965)2.38898872
46Bradycardia (HP:0001662)2.37451998
47Decreased muscle mass (HP:0003199)2.37429340
48Poor eye contact (HP:0000817)2.34852067
49Dysmetria (HP:0001310)2.33478835
50Epileptiform EEG discharges (HP:0011182)2.31571250
51Blue irides (HP:0000635)2.31449830
52Protruding tongue (HP:0010808)2.30897461
53Abnormality of the corticospinal tract (HP:0002492)2.30371824
54Agitation (HP:0000713)2.28783868
55Dysdiadochokinesis (HP:0002075)2.26229114
56Ankle clonus (HP:0011448)2.26177840
57Syncope (HP:0001279)2.26010833
58Supraventricular tachycardia (HP:0004755)2.25761179
59Abnormality of the calf musculature (HP:0001430)2.24834075
60Abnormality of midbrain morphology (HP:0002418)2.23544658
61Molar tooth sign on MRI (HP:0002419)2.23544658
62Truncal ataxia (HP:0002078)2.21420605
63Pancreatic cysts (HP:0001737)2.21020614
64Inability to walk (HP:0002540)2.19492077
65Supraventricular arrhythmia (HP:0005115)2.17626504
66Polyphagia (HP:0002591)2.14598991
67Prolonged QT interval (HP:0001657)2.13244947
68Pancreatic fibrosis (HP:0100732)2.12019480
69Congenital primary aphakia (HP:0007707)2.10943184
70Genetic anticipation (HP:0003743)2.10089268
71Abnormal eating behavior (HP:0100738)2.09765631
72Methylmalonic acidemia (HP:0002912)2.06684924
73Lower limb amyotrophy (HP:0007210)2.06162910
74Nephronophthisis (HP:0000090)2.05171935
75Incomplete penetrance (HP:0003829)2.04956744
76Abnormality of salivation (HP:0100755)2.04797475
77True hermaphroditism (HP:0010459)2.03398224
78Lower limb muscle weakness (HP:0007340)2.02198865
79Progressive inability to walk (HP:0002505)2.02010970
80Anxiety (HP:0000739)2.00013347
81Steppage gait (HP:0003376)1.98928862
82Optic nerve hypoplasia (HP:0000609)1.98348514
83Calf muscle hypertrophy (HP:0008981)1.98097894
84Scanning speech (HP:0002168)1.97921127
85Genital tract atresia (HP:0001827)1.97892318
86EEG with generalized epileptiform discharges (HP:0011198)1.97506054
87Ketosis (HP:0001946)1.97455993
88Nuclear cataract (HP:0100018)1.96598306
89Mutism (HP:0002300)1.96225230
90Bundle branch block (HP:0011710)1.95593752
91Abnormal mitochondria in muscle tissue (HP:0008316)1.93897536
92Sensory axonal neuropathy (HP:0003390)1.93805474
93Abnormal EKG (HP:0003115)1.93768589
94Muscle hypertrophy of the lower extremities (HP:0008968)1.93658101
95Abnormal social behavior (HP:0012433)1.93143144
96Impaired social interactions (HP:0000735)1.93143144
97Medial flaring of the eyebrow (HP:0010747)1.91770098
98Sleep apnea (HP:0010535)1.91401205
99Abnormality of aromatic amino acid family metabolism (HP:0004338)1.91277015
100Specific learning disability (HP:0001328)1.90996939
101Hypothermia (HP:0002045)1.90135496
102Acute encephalopathy (HP:0006846)1.90108356
103Nephrogenic diabetes insipidus (HP:0009806)1.88443188
104Vaginal atresia (HP:0000148)1.87693419
105Hyperglycemia (HP:0003074)1.87684590
106Torticollis (HP:0000473)1.87149749
107Left ventricular hypertrophy (HP:0001712)1.86826425
108Zonular cataract (HP:0010920)1.83109958
109Aqueductal stenosis (HP:0002410)1.82885224
110Diplopia (HP:0000651)1.82792963
111Abnormality of binocular vision (HP:0011514)1.82792963
112Muscular hypotonia of the trunk (HP:0008936)1.81265399
113Spastic gait (HP:0002064)1.80626980
114Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.80571517
115Degeneration of the lateral corticospinal tracts (HP:0002314)1.80571517
116Hypsarrhythmia (HP:0002521)1.80545786
117Hypomagnesemia (HP:0002917)1.80352075
118Type 2 muscle fiber atrophy (HP:0003554)1.79608880
119Hypoventilation (HP:0002791)1.79264929
120Urinary urgency (HP:0000012)1.79087528
121Hypobetalipoproteinemia (HP:0003563)1.78730153
122Increased corneal curvature (HP:0100692)1.78628571
123Keratoconus (HP:0000563)1.78628571
124Intestinal atresia (HP:0011100)1.78431037
125Exotropia (HP:0000577)1.77046345
126Ulnar claw (HP:0001178)1.75975537
127Epidermoid cyst (HP:0200040)1.75338441
128Mitochondrial inheritance (HP:0001427)1.74765675
129Aplasia/Hypoplasia involving the musculature (HP:0001460)1.74740702
130Popliteal pterygium (HP:0009756)1.72836239
131Methylmalonic aciduria (HP:0012120)1.72618849
132Insulin-resistant diabetes mellitus (HP:0000831)1.72031107
133Failure to thrive in infancy (HP:0001531)1.71646813
134Impaired smooth pursuit (HP:0007772)1.71337401
135Pachygyria (HP:0001302)1.71326171
136Abnormality of pain sensation (HP:0010832)1.69570851
137Impaired pain sensation (HP:0007328)1.69570851
138Focal dystonia (HP:0004373)1.68454679
139Abnormality of the labia minora (HP:0012880)1.67609677
140Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.67555297
141Diminished movement (HP:0002374)1.66455477
142Widely spaced teeth (HP:0000687)1.66364659
143Narrow nasal bridge (HP:0000446)1.66225459
144Supranuclear gaze palsy (HP:0000605)1.65855718
145Hypoplastic ischia (HP:0003175)1.65793716
146Pendular nystagmus (HP:0012043)1.63577639
147Esotropia (HP:0000565)1.62147632
148Neoplasm of the adrenal cortex (HP:0100641)1.61918153
149Abnormality of the pancreatic islet cells (HP:0006476)1.61223351
150Abnormality of endocrine pancreas physiology (HP:0012093)1.61223351
151Increased CSF lactate (HP:0002490)1.61093127

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK5.32550743
2NTRK34.14777923
3FRK4.05134035
4MARK12.85510097
5MAP3K42.84258702
6MAP2K72.80390814
7EPHA42.72489096
8MAP3K122.43429371
9TNIK2.36739710
10MAP3K92.33195160
11MINK12.19902232
12MAPK132.19344860
13OBSCN2.16298147
14DAPK22.04316582
15PLK22.03859409
16PRPF4B2.03342846
17WNK32.01182308
18MUSK2.00526006
19SIK31.91765429
20MAP2K41.73136216
21CDK191.68635993
22NTRK21.56602377
23GRK51.53968644
24STK38L1.50061439
25OXSR11.49171314
26CSNK1G31.42748097
27CCNB11.40738809
28PAK61.40706357
29CSNK1G11.38901013
30AKT31.36146481
31DAPK11.32346406
32CAMK2A1.27567604
33CAMK1G1.25208598
34RIPK41.18915330
35LATS21.17701932
36CDK51.16770782
37PINK11.14732708
38BCR1.14426389
39BMPR1B1.12559575
40KSR11.12247437
41TRIM281.11709460
42EPHA31.07733890
43PTK2B1.06822869
44MKNK21.06653737
45FGFR21.04772982
46WNK41.04147194
47CSNK1A1L1.03934699
48PRKCG1.03308008
49CAMK2B1.03144384
50LIMK11.02942395
51MYLK1.00730552
52SGK2231.00427119
53SGK4941.00427119
54NTRK10.99070118
55CAMKK20.99018524
56SGK20.96111707
57PAK30.93452403
58SIK20.92264257
59STK390.87563639
60NUAK10.86360480
61PHKG20.86263954
62PHKG10.86263954
63CDK180.83960634
64UHMK10.83531054
65CDK140.81907490
66PIK3CA0.80875665
67GRK10.79891872
68KSR20.78669101
69STK240.78269106
70BMPR20.77573384
71CAMK2D0.77010122
72CDK150.76261729
73INSRR0.75330473
74CDC42BPA0.75109719
75PRKCE0.73556176
76PKN10.72971474
77PNCK0.72903431
78CAMKK10.72735764
79MAP4K20.71243929
80TSSK60.69064869
81ARAF0.68741948
82CSNK1G20.68411691
83SGK10.67540933
84ADRBK20.67306032
85PRKCZ0.67001259
86FER0.66793744
87CAMK10.66300506
88MARK20.66094470
89CDK11A0.64341582
90ADRBK10.62382993
91TAF10.61461630
92CAMK1D0.59516980
93FES0.59290996
94MAP3K20.57635737
95RET0.55601494
96PIK3CG0.54975189
97ROCK10.54679012
98MAPKAPK50.54536348
99CSNK1D0.54200541
100NEK60.53538935
101PRKG10.52945480
102PRKACB0.52238443
103GRK70.52203926
104DMPK0.52080288
105CAMK40.52039481
106MAPK120.51609196
107PRKAA10.51463046
108SGK30.50450759
109PLK30.49213008
110DAPK30.48917573
111ERBB30.48419807
112FGR0.48320617
113DYRK20.47880561
114DDR20.47723038
115MST40.47513019
116PASK0.46633581
117STK110.46584547
118CAMK2G0.45128367
119WNK10.44782580
120CSNK1E0.44758856
121DYRK1A0.44534989
122ROCK20.42396916
123CSNK1A10.40486031
124FYN0.39168926
125CDK30.38942787
126PRKCH0.38662321
127PRKACA0.38345855
128TAOK30.38300003
129MAP3K60.38287153
130ZAK0.36885013
131TYRO30.36680426
132MAP2K10.35583925
133PRKCA0.35294045
134BRAF0.35008751
135YES10.34876563
136RPS6KA30.34866953
137PRKACG0.34267521

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.72126829
2Synaptic vesicle cycle_Homo sapiens_hsa047213.18962848
3Maturity onset diabetes of the young_Homo sapiens_hsa049502.90812285
4Circadian entrainment_Homo sapiens_hsa047132.67140097
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.64134826
6Olfactory transduction_Homo sapiens_hsa047402.60375703
7Butanoate metabolism_Homo sapiens_hsa006502.40861364
8Morphine addiction_Homo sapiens_hsa050322.40808859
9Glutamatergic synapse_Homo sapiens_hsa047242.40779987
10Long-term potentiation_Homo sapiens_hsa047202.39905420
11GABAergic synapse_Homo sapiens_hsa047272.34095919
12Amphetamine addiction_Homo sapiens_hsa050312.30212529
13Protein export_Homo sapiens_hsa030602.19324452
14Taste transduction_Homo sapiens_hsa047422.12141390
15Collecting duct acid secretion_Homo sapiens_hsa049662.09765028
16Serotonergic synapse_Homo sapiens_hsa047262.03880712
17Dopaminergic synapse_Homo sapiens_hsa047282.03259005
18Salivary secretion_Homo sapiens_hsa049701.99231788
19Insulin secretion_Homo sapiens_hsa049111.86931467
20Cardiac muscle contraction_Homo sapiens_hsa042601.74612243
21Long-term depression_Homo sapiens_hsa047301.74516574
22Cholinergic synapse_Homo sapiens_hsa047251.71808585
23Renin secretion_Homo sapiens_hsa049241.70176967
24Calcium signaling pathway_Homo sapiens_hsa040201.68130147
25Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.68006710
26Oxytocin signaling pathway_Homo sapiens_hsa049211.64429279
27Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.63818182
28Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.58823048
29Axon guidance_Homo sapiens_hsa043601.57113289
30Vitamin B6 metabolism_Homo sapiens_hsa007501.55809889
31Tryptophan metabolism_Homo sapiens_hsa003801.54596791
32Propanoate metabolism_Homo sapiens_hsa006401.53357986
33Aldosterone synthesis and secretion_Homo sapiens_hsa049251.49947447
34Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.49169925
35Dilated cardiomyopathy_Homo sapiens_hsa054141.45419289
36Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.43934937
37Cocaine addiction_Homo sapiens_hsa050301.40886006
38Gastric acid secretion_Homo sapiens_hsa049711.39334511
39Vibrio cholerae infection_Homo sapiens_hsa051101.37603701
40Primary bile acid biosynthesis_Homo sapiens_hsa001201.29947048
41Selenocompound metabolism_Homo sapiens_hsa004501.25919672
42Gap junction_Homo sapiens_hsa045401.25271257
43Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.25143865
44Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.24518596
45GnRH signaling pathway_Homo sapiens_hsa049121.24393677
46Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.23810918
47Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.21941523
48cAMP signaling pathway_Homo sapiens_hsa040241.20383649
49Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.19550458
50Oxidative phosphorylation_Homo sapiens_hsa001901.18468493
51cGMP-PKG signaling pathway_Homo sapiens_hsa040221.16573430
52Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.15388247
53Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.12793297
54Vascular smooth muscle contraction_Homo sapiens_hsa042701.11225706
55Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.10420738
56Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.08482598
57Melanogenesis_Homo sapiens_hsa049161.06009483
58Type II diabetes mellitus_Homo sapiens_hsa049301.05741300
59ErbB signaling pathway_Homo sapiens_hsa040121.05683474
60Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.05421472
61Alzheimers disease_Homo sapiens_hsa050101.01825060
62Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.98615415
63Peroxisome_Homo sapiens_hsa041460.96676878
64Ether lipid metabolism_Homo sapiens_hsa005650.94429922
65Estrogen signaling pathway_Homo sapiens_hsa049150.93781551
66Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.91216436
67Folate biosynthesis_Homo sapiens_hsa007900.90612578
68beta-Alanine metabolism_Homo sapiens_hsa004100.87803094
69Phosphatidylinositol signaling system_Homo sapiens_hsa040700.87347280
70Retinol metabolism_Homo sapiens_hsa008300.86521682
71Linoleic acid metabolism_Homo sapiens_hsa005910.85976615
72Phototransduction_Homo sapiens_hsa047440.83997925
73Glioma_Homo sapiens_hsa052140.83459553
74Fatty acid elongation_Homo sapiens_hsa000620.83076111
75Steroid hormone biosynthesis_Homo sapiens_hsa001400.81429254
76Basal transcription factors_Homo sapiens_hsa030220.80699546
77Parkinsons disease_Homo sapiens_hsa050120.80494149
78Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.79838071
79Pyruvate metabolism_Homo sapiens_hsa006200.79351614
80Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.78327168
81Nitrogen metabolism_Homo sapiens_hsa009100.77107714
82Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.76280708
83MAPK signaling pathway_Homo sapiens_hsa040100.75218449
84Histidine metabolism_Homo sapiens_hsa003400.75175497
85Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.74710097
86Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.73857006
87Caffeine metabolism_Homo sapiens_hsa002320.73351924
88Rheumatoid arthritis_Homo sapiens_hsa053230.71564951
89Regulation of autophagy_Homo sapiens_hsa041400.70349917
90Ras signaling pathway_Homo sapiens_hsa040140.69306603
91Bile secretion_Homo sapiens_hsa049760.69208591
92Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.67973497
93Ovarian steroidogenesis_Homo sapiens_hsa049130.66971261
94Phospholipase D signaling pathway_Homo sapiens_hsa040720.66941235
95Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.66432691
96Oocyte meiosis_Homo sapiens_hsa041140.66254407
97Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.66210319
98Cysteine and methionine metabolism_Homo sapiens_hsa002700.65577628
99Wnt signaling pathway_Homo sapiens_hsa043100.64513257
100Dorso-ventral axis formation_Homo sapiens_hsa043200.64462778
101Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.63730966
102Chemical carcinogenesis_Homo sapiens_hsa052040.62989379
103Pentose and glucuronate interconversions_Homo sapiens_hsa000400.62551983
104Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.61977803
105Mineral absorption_Homo sapiens_hsa049780.61086801
106Rap1 signaling pathway_Homo sapiens_hsa040150.60172049
107Thyroid hormone synthesis_Homo sapiens_hsa049180.59588143
108Steroid biosynthesis_Homo sapiens_hsa001000.59006588
109Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.58822559
110SNARE interactions in vesicular transport_Homo sapiens_hsa041300.58513254
111Huntingtons disease_Homo sapiens_hsa050160.58117948
112Choline metabolism in cancer_Homo sapiens_hsa052310.57796856
113Phagosome_Homo sapiens_hsa041450.56856059
114Pancreatic secretion_Homo sapiens_hsa049720.56366323
115Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.55054872
116Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.53188640
117Melanoma_Homo sapiens_hsa052180.52318930
118Phenylalanine metabolism_Homo sapiens_hsa003600.52248004
119Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.51854948
120Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.51754082
121ABC transporters_Homo sapiens_hsa020100.50936165
122Fatty acid metabolism_Homo sapiens_hsa012120.50927617
123Circadian rhythm_Homo sapiens_hsa047100.48998149
124Metabolic pathways_Homo sapiens_hsa011000.48569536
125Glucagon signaling pathway_Homo sapiens_hsa049220.47722617
126Hedgehog signaling pathway_Homo sapiens_hsa043400.46862866
127Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.46680965
128Renal cell carcinoma_Homo sapiens_hsa052110.43024402
129Sulfur metabolism_Homo sapiens_hsa009200.42702485
130Regulation of actin cytoskeleton_Homo sapiens_hsa048100.41751531
131African trypanosomiasis_Homo sapiens_hsa051430.39785474
132Tight junction_Homo sapiens_hsa045300.38632732
133Neurotrophin signaling pathway_Homo sapiens_hsa047220.35947775
134Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.34877686
135Sphingolipid signaling pathway_Homo sapiens_hsa040710.33687914
136Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.33662680
137Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.32187776
138Type I diabetes mellitus_Homo sapiens_hsa049400.31823375
139Endometrial cancer_Homo sapiens_hsa052130.31615642
140Insulin signaling pathway_Homo sapiens_hsa049100.30569495
141Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.30044093
142Alcoholism_Homo sapiens_hsa050340.29062407
143Hippo signaling pathway_Homo sapiens_hsa043900.28521488
144Thyroid hormone signaling pathway_Homo sapiens_hsa049190.28368149
145Focal adhesion_Homo sapiens_hsa045100.27230244
146VEGF signaling pathway_Homo sapiens_hsa043700.26078085
147Endocytosis_Homo sapiens_hsa041440.25818322
148Prion diseases_Homo sapiens_hsa050200.25473616

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