PALMD

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1muscle filament sliding (GO:0030049)4.71357459
2actin-myosin filament sliding (GO:0033275)4.71357459
3erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)4.69394167
4L-phenylalanine catabolic process (GO:0006559)4.69394167
5regulation of skeletal muscle contraction (GO:0014819)4.56869691
6erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)4.51862943
7L-phenylalanine metabolic process (GO:0006558)4.51862943
8regulation of sequestering of triglyceride (GO:0010889)4.43957893
9fatty acid transmembrane transport (GO:1902001)4.40379351
10triglyceride-rich lipoprotein particle remodeling (GO:0034370)4.26721368
11alpha-linolenic acid metabolic process (GO:0036109)4.21360644
12positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)4.11881829
13carnitine shuttle (GO:0006853)4.09507539
14fatty acid beta-oxidation (GO:0006635)4.08648859
15myofibril assembly (GO:0030239)4.01920771
16regulation of triglyceride catabolic process (GO:0010896)4.01015897
17cardiac myofibril assembly (GO:0055003)3.99063660
18actin-mediated cell contraction (GO:0070252)3.97845502
19regulation of sarcomere organization (GO:0060297)3.97617575
20positive regulation of fatty acid beta-oxidation (GO:0032000)3.96491687
21aromatic amino acid family catabolic process (GO:0009074)3.91671136
22fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.87012094
23fatty acid oxidation (GO:0019395)3.79173619
24regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)3.78828276
25sarcomere organization (GO:0045214)3.78041176
26fatty acid catabolic process (GO:0009062)3.76915998
27complement activation, alternative pathway (GO:0006957)3.75635846
28positive regulation of fatty acid oxidation (GO:0046321)3.73739516
29sarcoplasmic reticulum calcium ion transport (GO:0070296)3.73731164
30regulation of cell communication by electrical coupling (GO:0010649)3.73633899
31negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.73236159
32acylglycerol homeostasis (GO:0055090)3.72951478
33triglyceride homeostasis (GO:0070328)3.72951478
34bile acid biosynthetic process (GO:0006699)3.72727252
35lipid oxidation (GO:0034440)3.72520562
36negative regulation of protein localization to cell surface (GO:2000009)3.72308845
37response to stimulus involved in regulation of muscle adaptation (GO:0014874)3.68532617
38low-density lipoprotein particle clearance (GO:0034383)3.68346709
39NADH metabolic process (GO:0006734)3.67990289
40fatty acid homeostasis (GO:0055089)3.67052142
41endothelium development (GO:0003158)3.65999982
42lysine metabolic process (GO:0006553)3.60492414
43lysine catabolic process (GO:0006554)3.60492414
44regulation of relaxation of muscle (GO:1901077)3.59458703
45plasma lipoprotein particle clearance (GO:0034381)3.57198965
46retina vasculature morphogenesis in camera-type eye (GO:0061299)3.54833158
47amino-acid betaine metabolic process (GO:0006577)3.53990035
48regulation of protein activation cascade (GO:2000257)3.53653418
49acetyl-CoA metabolic process (GO:0006084)3.53508218
50regulation of lipoprotein metabolic process (GO:0050746)3.52801915
51high-density lipoprotein particle remodeling (GO:0034375)3.52306488
52positive regulation of lipid catabolic process (GO:0050996)3.51256541
53monocarboxylic acid catabolic process (GO:0072329)3.50526183
54kynurenine metabolic process (GO:0070189)3.49708305
55sulfur amino acid catabolic process (GO:0000098)3.49184876
56biotin metabolic process (GO:0006768)3.46725896
57regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO3.46361048
58triglyceride catabolic process (GO:0019433)3.44287211
59glyoxylate metabolic process (GO:0046487)3.42416837
60negative regulation of fibrinolysis (GO:0051918)3.42413018
61protein carboxylation (GO:0018214)3.38564634
62peptidyl-glutamic acid carboxylation (GO:0017187)3.38564634
63negative regulation of lipase activity (GO:0060192)3.38049533
64regulation of complement activation (GO:0030449)3.37991606
65acylglycerol catabolic process (GO:0046464)3.37487810
66neutral lipid catabolic process (GO:0046461)3.37487810
67tyrosine metabolic process (GO:0006570)3.37087233
68short-chain fatty acid metabolic process (GO:0046459)3.34836975
69cellular ketone body metabolic process (GO:0046950)3.34429074
702-oxoglutarate metabolic process (GO:0006103)3.34015213
71ethanol metabolic process (GO:0006067)3.32796535
72urea metabolic process (GO:0019627)3.32369813
73urea cycle (GO:0000050)3.32369813
74regulation of fibrinolysis (GO:0051917)3.31642462
75cellular response to epinephrine stimulus (GO:0071872)3.29566127
76regulation of fatty acid oxidation (GO:0046320)3.28598316
77reverse cholesterol transport (GO:0043691)3.26028494
78indole-containing compound catabolic process (GO:0042436)3.24346979
79indolalkylamine catabolic process (GO:0046218)3.24346979
80tryptophan catabolic process (GO:0006569)3.24346979
81carnitine metabolic process (GO:0009437)3.24128826
82plasma membrane repair (GO:0001778)3.23989444
83negative regulation of potassium ion transmembrane transport (GO:1901380)3.23185268
84bile acid metabolic process (GO:0008206)3.19463035
85response to epinephrine (GO:0071871)3.19322546
86valine metabolic process (GO:0006573)3.18113923
87carnitine transmembrane transport (GO:1902603)3.17840855
88creatine metabolic process (GO:0006600)3.17603128
89tryptophan metabolic process (GO:0006568)3.17467649
90regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)3.13381532
91lipid particle organization (GO:0034389)3.12452856
92regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.12378947
93bundle of His cell to Purkinje myocyte communication (GO:0086069)3.10353051
94cardiac muscle contraction (GO:0060048)3.09335237
95protein-lipid complex remodeling (GO:0034368)3.09194083
96macromolecular complex remodeling (GO:0034367)3.09194083
97plasma lipoprotein particle remodeling (GO:0034369)3.09194083
98nitrogen cycle metabolic process (GO:0071941)3.07663344
99transcytosis (GO:0045056)3.06632536
100glycerolipid catabolic process (GO:0046503)3.03967450
101alkaloid metabolic process (GO:0009820)3.03833460
102striated muscle contraction (GO:0006941)3.03649199
103coenzyme catabolic process (GO:0009109)3.01962453
104branched-chain amino acid catabolic process (GO:0009083)3.01538312
105phospholipid homeostasis (GO:0055091)3.00652500
106skeletal muscle contraction (GO:0003009)3.00587150
107phospholipid efflux (GO:0033700)2.99941987
108lymphangiogenesis (GO:0001946)2.99923300
109cysteine metabolic process (GO:0006534)2.98076020
110regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)2.97888810
111negative regulation of heart growth (GO:0061117)2.97609936
112negative regulation of cardiac muscle tissue growth (GO:0055022)2.97609936
113actin filament-based movement (GO:0030048)2.97302063
114carnitine transport (GO:0015879)2.96924895
115amino-acid betaine transport (GO:0015838)2.96924895
116regulation of actin filament-based movement (GO:1903115)2.96851799
117regulation of fatty acid beta-oxidation (GO:0031998)2.96846372
118actomyosin structure organization (GO:0031032)2.96758159
119primary alcohol catabolic process (GO:0034310)2.96399934
120aromatic amino acid family metabolic process (GO:0009072)2.94788954
121alpha-amino acid catabolic process (GO:1901606)2.93497072
122ethanol oxidation (GO:0006069)2.93271183
123positive regulation of lipid storage (GO:0010884)2.92872721
124regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)2.92023836
125cGMP-mediated signaling (GO:0019934)2.91488814
126organic acid catabolic process (GO:0016054)2.90590714
127carboxylic acid catabolic process (GO:0046395)2.90590714
128skeletal muscle adaptation (GO:0043501)2.90413827
129homocysteine metabolic process (GO:0050667)2.87381580
130glomerular filtration (GO:0003094)2.86752894
131brown fat cell differentiation (GO:0050873)2.86676724
132regulation of cholesterol esterification (GO:0010872)2.85495681
133striated muscle atrophy (GO:0014891)2.84949020
134ketone body metabolic process (GO:1902224)2.84743164
135desmosome organization (GO:0002934)2.84405542
136polyol transport (GO:0015791)2.84397291
137positive regulation of glycolytic process (GO:0045821)2.84366408
138fibrinolysis (GO:0042730)2.82916035
139regulation of triglyceride metabolic process (GO:0090207)2.81736864
140regulation of cholesterol metabolic process (GO:0090181)2.81429283
141positive regulation of fatty acid metabolic process (GO:0045923)2.80957326
142diacylglycerol metabolic process (GO:0046339)2.80063271
143branched-chain amino acid metabolic process (GO:0009081)2.79237911
144serine family amino acid catabolic process (GO:0009071)2.78802795
145response to muscle activity (GO:0014850)2.78652103
146aspartate family amino acid catabolic process (GO:0009068)2.76453048
147cellular amino acid catabolic process (GO:0009063)2.75809001
148epoxygenase P450 pathway (GO:0019373)2.74718269
149response to inactivity (GO:0014854)2.74238488
150positive regulation of triglyceride metabolic process (GO:0090208)2.73862373
151acyl-CoA metabolic process (GO:0006637)2.73759301
152thioester metabolic process (GO:0035383)2.73759301
153ovulation from ovarian follicle (GO:0001542)2.72517578
154thioester biosynthetic process (GO:0035384)2.72092230
155acyl-CoA biosynthetic process (GO:0071616)2.72092230
156negative regulation of macrophage derived foam cell differentiation (GO:0010745)2.69106092
157muscle contraction (GO:0006936)2.69015134
158primary alcohol metabolic process (GO:0034308)2.68110810
159negative regulation of nitric-oxide synthase activity (GO:0051001)2.66334728
160detection of calcium ion (GO:0005513)2.65869378
161myotube cell development (GO:0014904)2.64114855
162cardiac muscle hypertrophy (GO:0003300)2.61944928
163positive regulation of glomerulus development (GO:0090193)2.61825819
164regulation of cholesterol storage (GO:0010885)2.58858721
165regulation of striated muscle contraction (GO:0006942)2.56949602
166renal filtration (GO:0097205)2.56688538
167positive regulation of vascular permeability (GO:0043117)2.56360118
168heart contraction (GO:0060047)2.55678409
169heart process (GO:0003015)2.55678409
170striated muscle hypertrophy (GO:0014897)2.55445214
171glycerol metabolic process (GO:0006071)2.55293845
172blood vessel maturation (GO:0001955)2.55244942
173ventricular cardiac muscle cell action potential (GO:0086005)2.55032774
174regulation of membrane repolarization (GO:0060306)2.50317039
175positive regulation of calcium ion transmembrane transporter activity (GO:1901021)2.48906694
176skeletal muscle fiber development (GO:0048741)2.48608408
177muscle system process (GO:0003012)2.48042849
178regulation of the force of heart contraction (GO:0002026)2.47936137
179heart trabecula formation (GO:0060347)2.46287549
180glycogen catabolic process (GO:0005980)2.45550546
181cardiac muscle tissue morphogenesis (GO:0055008)2.45300240
182endocrine hormone secretion (GO:0060986)2.44496425

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1PPARG_19300518_ChIP-PET_3T3-L1_Mouse6.40692114
2ESR1_17901129_ChIP-ChIP_LIVER_Mouse6.19239003
3* RXR_22158963_ChIP-Seq_LIVER_Mouse4.39926422
4* PPARA_22158963_ChIP-Seq_LIVER_Mouse3.75486477
5LXR_22158963_ChIP-Seq_LIVER_Mouse3.71374538
6FOXO1_23066095_ChIP-Seq_LIVER_Mouse3.24306694
7TP63_17297297_ChIP-ChIP_HaCaT_Human2.91229273
8* EGR1_23403033_ChIP-Seq_LIVER_Mouse2.90957757
9NR1I2_20693526_ChIP-Seq_LIVER_Mouse2.80245205
10TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.63168414
11GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.24818407
12CLOCK_20551151_ChIP-Seq_293T_Human2.03559413
13VDR_22108803_ChIP-Seq_LS180_Human1.94995364
14CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.90647630
15ZNF263_19887448_ChIP-Seq_K562_Human1.86359370
16EZH2_22144423_ChIP-Seq_EOC_Human1.82322294
17RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.81877800
18EP300_21415370_ChIP-Seq_HL-1_Mouse1.73472697
19TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.73227268
20TRIM28_21343339_ChIP-Seq_HEK293_Human1.71726325
21* RARG_19884340_ChIP-ChIP_MEFs_Mouse1.70302487
22CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.70256750
23ESR2_21235772_ChIP-Seq_MCF-7_Human1.60012630
24CDX2_19796622_ChIP-Seq_MESCs_Mouse1.58032158
25ESR1_20079471_ChIP-ChIP_T-47D_Human1.55383506
26ZFP57_27257070_Chip-Seq_ESCs_Mouse1.53066831
27SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.49767854
28GATA1_22025678_ChIP-Seq_K562_Human1.47896505
29TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.45988080
30ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.38018257
31* SOX9_24532713_ChIP-Seq_HFSC_Mouse1.31267698
32SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.30960464
33ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.30078350
34SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.29652372
35BCAT_22108803_ChIP-Seq_LS180_Human1.29336319
36ESR1_21235772_ChIP-Seq_MCF-7_Human1.28142025
37PIAS1_25552417_ChIP-Seq_VCAP_Human1.27798714
38BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.26453798
39ZNF217_24962896_ChIP-Seq_MCF-7_Human1.26080364
40SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.25892222
41RNF2_18974828_ChIP-Seq_MESCs_Mouse1.25295234
42EZH2_18974828_ChIP-Seq_MESCs_Mouse1.25295234
43THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.24448874
44POU3F2_20337985_ChIP-ChIP_501MEL_Human1.22501521
45NRF2_20460467_ChIP-Seq_MEFs_Mouse1.22420049
46NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.22420049
47MTF2_20144788_ChIP-Seq_MESCs_Mouse1.20942256
48* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.19866849
49* TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.18838574
50FOXA2_19822575_ChIP-Seq_HepG2_Human1.18446071
51PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.18331088
52TAF15_26573619_Chip-Seq_HEK293_Human1.17963704
53SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.17638293
54EED_16625203_ChIP-ChIP_MESCs_Mouse1.17387130
55GATA2_21666600_ChIP-Seq_HMVEC_Human1.16427790
56TCF4_18268006_ChIP-ChIP_LS174T_Human1.15391145
57NR3C1_21868756_ChIP-Seq_MCF10A_Human1.15031993
58PPAR_26484153_Chip-Seq_NCI-H1993_Human1.14736744
59* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.14436947
60EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.11378161
61GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.11174326
62DROSHA_22980978_ChIP-Seq_HELA_Human1.11089038
63* TBX20_22328084_ChIP-Seq_HEART_Mouse1.11030165
64* TBX20_22080862_ChIP-Seq_HEART_Mouse1.11030165
65NR3C1_23031785_ChIP-Seq_PC12_Mouse1.09677978
66OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.08553669
67FOXO3_23340844_ChIP-Seq_DLD1_Human1.08413855
68* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.07176000
69JARID2_20075857_ChIP-Seq_MESCs_Mouse1.07166875
70* CJUN_26792858_Chip-Seq_BT549_Human1.07079067
71PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.06223850
72GBX2_23144817_ChIP-Seq_PC3_Human1.05948234
73PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.05857345
74IGF1R_20145208_ChIP-Seq_DFB_Human1.05524132
75AR_21572438_ChIP-Seq_LNCaP_Human1.05403319
76EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.02497036
77AHR_22903824_ChIP-Seq_MCF-7_Human1.01850822
78STAT3_23295773_ChIP-Seq_U87_Human0.99261281
79ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.98938150
80CTNNB1_20460455_ChIP-Seq_HCT116_Human0.98920173
81TOP2B_26459242_ChIP-Seq_MCF-7_Human0.97129437
82FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.96413428
83TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.95777401
84PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.94729316
85STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.94413218
86SALL4_18804426_ChIP-ChIP_XEN_Mouse0.94176067
87HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.93568666
88SOX2_21211035_ChIP-Seq_LN229_Gbm0.93071692
89SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.92061957
90TCF4_23295773_ChIP-Seq_U87_Human0.91923541
91JARID2_20064375_ChIP-Seq_MESCs_Mouse0.91123858
92SOX2_20726797_ChIP-Seq_SW620_Human0.90850886
93* NFIB_24661679_ChIP-Seq_LUNG_Mouse0.90836528
94MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.90428634
95CBX2_27304074_Chip-Seq_ESCs_Mouse0.89960741
96SMAD3_21741376_ChIP-Seq_EPCs_Human0.89763399
97P300_19829295_ChIP-Seq_ESCs_Human0.88956861
98MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.87447251
99EZH2_27304074_Chip-Seq_ESCs_Mouse0.86941141
100CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.85948169
101SMAD4_21741376_ChIP-Seq_HESCs_Human0.85761991
102STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.85094406
103SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.83948600
104ERG_21242973_ChIP-ChIP_JURKAT_Human0.83632034
105AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.83454222
106TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.83362309
107* TP53_18474530_ChIP-ChIP_U2OS_Human0.83259248
108EZH2_27294783_Chip-Seq_ESCs_Mouse0.82393807
109* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.80236198
110TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.79921832
111ARNT_22903824_ChIP-Seq_MCF-7_Human0.79891660
112CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.79851515
113HTT_18923047_ChIP-ChIP_STHdh_Human0.79719808
114SUZ12_27294783_Chip-Seq_ESCs_Mouse0.77461968
115CDX2_20551321_ChIP-Seq_CACO-2_Human0.77427975
116SMAD4_21799915_ChIP-Seq_A2780_Human0.76358236
117ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.75399064
118UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.74157203
119* TP63_23658742_ChIP-Seq_EP156T_Human0.73178334
120WT1_19549856_ChIP-ChIP_CCG9911_Human0.73171443
121PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.72277693
122* AR_25329375_ChIP-Seq_VCAP_Human0.71264628
123SMAD_19615063_ChIP-ChIP_OVARY_Human0.71240203
124SMAD3_21741376_ChIP-Seq_HESCs_Human0.70394146
125AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.70220991
126CTCF_27219007_Chip-Seq_Bcells_Human0.70115785
127CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.69857163
128* SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.69642076
129* AUTS2_25519132_ChIP-Seq_293T-REX_Human0.69389842
130HNF4A_19822575_ChIP-Seq_HepG2_Human0.68877935
131RXR_22108803_ChIP-Seq_LS180_Human0.67838123
132* PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.66797806
133WT1_25993318_ChIP-Seq_PODOCYTE_Human0.66508333

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system4.96827348
2MP0005085_abnormal_gallbladder_physiolo4.36852860
3MP0005360_urolithiasis4.29030633
4MP0005365_abnormal_bile_salt4.02579921
5MP0002837_dystrophic_cardiac_calcinosis3.39348308
6MP0005670_abnormal_white_adipose3.26562721
7MP0003950_abnormal_plasma_membrane3.18782044
8MP0008875_abnormal_xenobiotic_pharmacok3.11477220
9MP0004145_abnormal_muscle_electrophysio3.08418085
10MP0010329_abnormal_lipoprotein_level3.01154860
11MP0004130_abnormal_muscle_cell2.76999168
12MP0003252_abnormal_bile_duct2.39619553
13MP0002822_catalepsy2.22972135
14MP0005666_abnormal_adipose_tissue2.22970493
15MP0003191_abnormal_cellular_cholesterol2.00232156
16MP0002118_abnormal_lipid_homeostasis1.91878828
17MP0000751_myopathy1.91279393
18MP0005083_abnormal_biliary_tract1.90620406
19MP0002106_abnormal_muscle_physiology1.87274820
20MP0004215_abnormal_myocardial_fiber1.78915901
21MP0010368_abnormal_lymphatic_system1.78355546
22MP0005369_muscle_phenotype1.76809455
23MP0005332_abnormal_amino_acid1.73935547
24MP0005275_abnormal_skin_tensile1.71911701
25MP0003806_abnormal_nucleotide_metabolis1.69158536
26MP0004185_abnormal_adipocyte_glucose1.66179748
27MP0004272_abnormal_basement_membrane1.59072844
28MP0003646_muscle_fatigue1.59012137
29MP0002254_reproductive_system_inflammat1.58419907
30MP0002796_impaired_skin_barrier1.58246741
31MP0005330_cardiomyopathy1.55979292
32MP0000747_muscle_weakness1.55384832
33MP0003705_abnormal_hypodermis_morpholog1.53316619
34MP0002971_abnormal_brown_adipose1.52439743
35MP0005375_adipose_tissue_phenotype1.52377489
36MP0000609_abnormal_liver_physiology1.51466728
37MP0006138_congestive_heart_failure1.49223370
38MP0004084_abnormal_cardiac_muscle1.47015331
39MP0004036_abnormal_muscle_relaxation1.46713860
40MP0000013_abnormal_adipose_tissue1.46232328
41MP0001879_abnormal_lymphatic_vessel1.44107209
42MP0003195_calcinosis1.41617235
43MP0001666_abnormal_nutrient_absorption1.41360837
44MP0009379_abnormal_foot_pigmentation1.40471871
45MP0005167_abnormal_blood-brain_barrier1.38016753
46MP0005503_abnormal_tendon_morphology1.37618301
47MP0002138_abnormal_hepatobiliary_system1.35865620
48MP0004019_abnormal_vitamin_homeostasis1.35710971
49MP0005319_abnormal_enzyme/_coenzyme1.34017257
50MP0009840_abnormal_foam_cell1.32902167
51MP0005535_abnormal_body_temperature1.32365171
52MP0003724_increased_susceptibility_to1.31467386
53MP0000749_muscle_degeneration1.31137645
54MP0003959_abnormal_lean_body1.29738487
55MP0002876_abnormal_thyroid_physiology1.28167473
56MP0003279_aneurysm1.28066590
57MP0002972_abnormal_cardiac_muscle1.25235991
58MP0005620_abnormal_muscle_contractility1.24812776
59MP0008775_abnormal_heart_ventricle1.21941382
60MP0005584_abnormal_enzyme/coenzyme_acti1.17981742
61MP0009697_abnormal_copulation1.17895777
62MP0001544_abnormal_cardiovascular_syste1.17459499
63MP0005385_cardiovascular_system_phenoty1.17459499
64MP0005334_abnormal_fat_pad1.14862604
65MP0004087_abnormal_muscle_fiber1.10041665
66MP0000733_abnormal_muscle_development1.07292957
67MP0006036_abnormal_mitochondrial_physio1.05111024
68MP0008438_abnormal_cutaneous_collagen1.05014280
69MP0003828_pulmonary_edema1.04987785
70MP0002638_abnormal_pupillary_reflex1.04847782
71MP0004484_altered_response_of1.03793435
72MP0002332_abnormal_exercise_endurance1.03740671
73MP0002060_abnormal_skin_morphology1.03192177
74MP0000767_abnormal_smooth_muscle1.02000313
75MP0003186_abnormal_redox_activity0.97974506
76MP0000003_abnormal_adipose_tissue0.97327274
77MP0009115_abnormal_fat_cell0.96446006
78MP0010234_abnormal_vibrissa_follicle0.96397783
79MP0006276_abnormal_autonomic_nervous0.94041974
80MP0002078_abnormal_glucose_homeostasis0.93469318
81MP0009643_abnormal_urine_homeostasis0.93316277
82MP0003868_abnormal_feces_composition0.92577231
83MP0004233_abnormal_muscle_weight0.90809436
84MP0000230_abnormal_systemic_arterial0.89538323
85MP0004085_abnormal_heartbeat0.88651202
86MP0010630_abnormal_cardiac_muscle0.85677556
87MP0000750_abnormal_muscle_regeneration0.85363072
88MP0001764_abnormal_homeostasis0.84574378
89MP0002933_joint_inflammation0.84197800
90MP0002128_abnormal_blood_circulation0.83485948
91MP0003011_delayed_dark_adaptation0.82969679
92MP0000249_abnormal_blood_vessel0.81539516
93MP0002127_abnormal_cardiovascular_syste0.80484690
94MP0000579_abnormal_nail_morphology0.80160249
95MP0005266_abnormal_metabolism0.79876327
96MP0002909_abnormal_adrenal_gland0.79749235
97MP0001756_abnormal_urination0.79543930
98MP0005165_increased_susceptibility_to0.79196609
99MP0004147_increased_porphyrin_level0.78582946
100MP0000266_abnormal_heart_morphology0.75343971
101MP0005084_abnormal_gallbladder_morpholo0.74963131
102MP0003566_abnormal_cell_adhesion0.74526075
103MP0000538_abnormal_urinary_bladder0.72471150
104MP0005452_abnormal_adipose_tissue0.72413328
105MP0005647_abnormal_sex_gland0.72036172
106MP0000759_abnormal_skeletal_muscle0.70982501
107MP0002269_muscular_atrophy0.70477256
108MP0004858_abnormal_nervous_system0.70092151
109MP0002295_abnormal_pulmonary_circulatio0.69440105
110MP0008874_decreased_physiological_sensi0.69411222
111MP0001661_extended_life_span0.68871249
112MP0002970_abnormal_white_adipose0.68250621
113MP0009780_abnormal_chondrocyte_physiolo0.68032861
114MP0005448_abnormal_energy_balance0.67950111
115MP0005595_abnormal_vascular_smooth0.66712573
116MP0002108_abnormal_muscle_morphology0.66493141
117MP0003137_abnormal_impulse_conducting0.65940664
118MP0005409_darkened_coat_color0.65050439
119MP0000343_altered_response_to0.64941225
120MP0004510_myositis0.64772921
121MP0003948_abnormal_gas_homeostasis0.63735266
122MP0005623_abnormal_meninges_morphology0.59940025
123MP0002896_abnormal_bone_mineralization0.59341927
124MP0005187_abnormal_penis_morphology0.57435048
125MP0005164_abnormal_response_to0.56553844
126MP0003690_abnormal_glial_cell0.54960333
127MP0001958_emphysema0.53015554
128MP0003045_fibrosis0.52085656
129MP0001614_abnormal_blood_vessel0.51758996

Predicted human phenotypes

RankGene SetZ-score
1Muscle fiber inclusion bodies (HP:0100299)5.44793099
2Nemaline bodies (HP:0003798)5.41724089
3Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)5.35003920
4Type 1 muscle fiber predominance (HP:0003803)5.04861831
5Asymmetric septal hypertrophy (HP:0001670)4.88665518
6Deep venous thrombosis (HP:0002625)4.70823374
7Xanthomatosis (HP:0000991)4.49320879
8Abnormality of aromatic amino acid family metabolism (HP:0004338)4.35520310
9Hypoglycemic coma (HP:0001325)4.31059586
10Hyperlipoproteinemia (HP:0010980)4.22051958
11Intrahepatic cholestasis (HP:0001406)4.17684285
12Bundle branch block (HP:0011710)4.03279060
13Neck muscle weakness (HP:0000467)3.94339429
14Complement deficiency (HP:0004431)3.89983788
15Right ventricular cardiomyopathy (HP:0011663)3.86533345
16Hypoalphalipoproteinemia (HP:0003233)3.82084268
17Hyperammonemia (HP:0001987)3.81589012
18Hyperglycinuria (HP:0003108)3.81336584
19Ketosis (HP:0001946)3.75387204
20Subaortic stenosis (HP:0001682)3.73501919
21Abnormality of the left ventricular outflow tract (HP:0011103)3.73501919
22Abnormality of monocarboxylic acid metabolism (HP:0010996)3.70456406
23Prolonged partial thromboplastin time (HP:0003645)3.70402911
24Distal arthrogryposis (HP:0005684)3.67976298
25EMG: myopathic abnormalities (HP:0003458)3.61467247
26Abnormality of fatty-acid metabolism (HP:0004359)3.61048234
27Increased variability in muscle fiber diameter (HP:0003557)3.54643631
28Epidermoid cyst (HP:0200040)3.41358995
29Sudden death (HP:0001699)3.39447286
30Abnormality of glycine metabolism (HP:0010895)3.36920528
31Abnormality of serine family amino acid metabolism (HP:0010894)3.36920528
32Ketoacidosis (HP:0001993)3.36168686
33Abnormality of skeletal muscle fiber size (HP:0012084)3.33747526
34Myoglobinuria (HP:0002913)3.30829424
35Hypolipoproteinemia (HP:0010981)3.29992032
36Abnormality of the level of lipoprotein cholesterol (HP:0010979)3.27461739
37Hyporeflexia of lower limbs (HP:0002600)3.25792052
38Round ear (HP:0100830)3.24348935
39Protrusio acetabuli (HP:0003179)3.15657672
40Hyperglycinemia (HP:0002154)3.13411072
41Hypobetalipoproteinemia (HP:0003563)3.11190431
42Exercise-induced myalgia (HP:0003738)3.07657216
43Oligomenorrhea (HP:0000876)3.05267606
44Heart block (HP:0012722)3.04452914
45Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.02627677
46Abnormality of dicarboxylic acid metabolism (HP:0010995)3.00581846
47Dicarboxylic aciduria (HP:0003215)3.00581846
48Gowers sign (HP:0003391)2.99862888
49Acanthosis nigricans (HP:0000956)2.96974221
50Rimmed vacuoles (HP:0003805)2.94110204
51Ventricular tachycardia (HP:0004756)2.93335051
52Abnormal atrioventricular conduction (HP:0005150)2.91775616
53Dilated cardiomyopathy (HP:0001644)2.84153404
54Aortic aneurysm (HP:0004942)2.81319115
55Cerebral edema (HP:0002181)2.78875720
56Abnormality of glutamine family amino acid metabolism (HP:0010902)2.74069945
57Increased connective tissue (HP:0009025)2.73624217
58Frequent falls (HP:0002359)2.72832576
59Hypercholesterolemia (HP:0003124)2.70366021
60Abnormality of complement system (HP:0005339)2.67407813
61Ulnar deviation of the wrist (HP:0003049)2.64249010
62Arterial tortuosity (HP:0005116)2.60708938
63Spinal rigidity (HP:0003306)2.60240520
64Vascular tortuosity (HP:0004948)2.60095436
65Joint hemorrhage (HP:0005261)2.59298330
66Abnormality of the common coagulation pathway (HP:0010990)2.59071885
67Rhabdomyolysis (HP:0003201)2.58821560
68Hypothermia (HP:0002045)2.58310239
69Areflexia of lower limbs (HP:0002522)2.57110160
70Palpitations (HP:0001962)2.55995535
71EMG: neuropathic changes (HP:0003445)2.51844250
72Myotonia (HP:0002486)2.46615685
73Hypertriglyceridemia (HP:0002155)2.45817762
74Metabolic acidosis (HP:0001942)2.45674128
75Muscle fiber splitting (HP:0003555)2.44033294
76Ventricular arrhythmia (HP:0004308)2.43767029
77Skin nodule (HP:0200036)2.40372679
78Hemorrhage of the eye (HP:0011885)2.40166650
79Lethargy (HP:0001254)2.39794658
80Muscle stiffness (HP:0003552)2.39491147
81Abnormality of aspartate family amino acid metabolism (HP:0010899)2.36709837
82Amyloidosis (HP:0011034)2.36058549
83Scapular winging (HP:0003691)2.33724853
84Generalized aminoaciduria (HP:0002909)2.33301975
85Difficulty running (HP:0009046)2.32852360
86Lymphangioma (HP:0100764)2.32200339
87Neonatal onset (HP:0003623)2.31119246
88Calf muscle hypertrophy (HP:0008981)2.29502334
89Prolonged QT interval (HP:0001657)2.29064046
90Hepatic necrosis (HP:0002605)2.28736850
91Hip contracture (HP:0003273)2.27529611
92Delayed CNS myelination (HP:0002188)2.27438734
93Malignant hyperthermia (HP:0002047)2.26763258
94Mildly elevated creatine phosphokinase (HP:0008180)2.26167272
95Exercise-induced muscle cramps (HP:0003710)2.24500077
96Increased muscle lipid content (HP:0009058)2.21265494
97Myocardial infarction (HP:0001658)2.20795511
98Neonatal hypoglycemia (HP:0001998)2.20285428
99Hyperglycemia (HP:0003074)2.18493289
100Distal lower limb muscle weakness (HP:0009053)2.17902155
101Syncope (HP:0001279)2.17414322
102Pigmentary retinal degeneration (HP:0001146)2.16724702
103Fat malabsorption (HP:0002630)2.15847404
104Esophageal varix (HP:0002040)2.14933955
105Lipoatrophy (HP:0100578)2.14869900
106Hypoglycemic seizures (HP:0002173)2.13901442
107Abnormality of serum amino acid levels (HP:0003112)2.13481856
108Conjugated hyperbilirubinemia (HP:0002908)2.13194588
109Abnormality of the intrinsic pathway (HP:0010989)2.12899054
110Abnormality of methionine metabolism (HP:0010901)2.12645508
111Muscle hypertrophy of the lower extremities (HP:0008968)2.11787964
112Atrial fibrillation (HP:0005110)2.11172949
113Absent phalangeal crease (HP:0006109)2.10001041
114Cerebral hemorrhage (HP:0001342)2.09473248
115Hyperinsulinemic hypoglycemia (HP:0000825)2.07670965
116Acute encephalopathy (HP:0006846)2.06485365
117Vomiting (HP:0002013)2.05934121
118Abnormality of purine metabolism (HP:0004352)2.01818866
119Centrally nucleated skeletal muscle fibers (HP:0003687)2.01787524
120Cholelithiasis (HP:0001081)2.01457710
121Hyperkalemia (HP:0002153)2.01080824
122Abnormality of sulfur amino acid metabolism (HP:0004339)2.00945595
123Myopathic facies (HP:0002058)2.00095695
124Limited hip movement (HP:0008800)1.98638550
125Atrioventricular block (HP:0001678)1.98072878
126Primary atrial arrhythmia (HP:0001692)1.97583073
127Abnormal hemoglobin (HP:0011902)1.97508824
128Abnormality of proline metabolism (HP:0010907)1.96510517
129Hydroxyprolinuria (HP:0003080)1.96510517
130Polycythemia (HP:0001901)1.96290866
131Abnormal gallbladder morphology (HP:0012437)1.94916975
132Popliteal pterygium (HP:0009756)1.94578236
133Vascular calcification (HP:0004934)1.93607711
134Conjunctival hamartoma (HP:0100780)1.92812186
135Generalized muscle weakness (HP:0003324)1.92014849
136Abnormality of the calf musculature (HP:0001430)1.87649892
137Bulbar palsy (HP:0001283)1.87353994
138Hyperbilirubinemia (HP:0002904)1.86820872
139Abnormality of the foot musculature (HP:0001436)1.86749418
140Nausea (HP:0002018)1.86493423
141Supraventricular arrhythmia (HP:0005115)1.85965894
142Insulin-resistant diabetes mellitus (HP:0000831)1.85744827
143Cardiovascular calcification (HP:0011915)1.85681160
144Steppage gait (HP:0003376)1.84742220
145Supraventricular tachycardia (HP:0004755)1.83747364
146Renal cortical cysts (HP:0000803)1.80834634
147Fatigable weakness (HP:0003473)1.79821504
148Abnormality of the neuromuscular junction (HP:0003398)1.79821504
149Hypotrichosis (HP:0001006)1.79288258
150Left ventricular hypertrophy (HP:0001712)1.76997708
151Foot dorsiflexor weakness (HP:0009027)1.76483151
152Calcaneovalgus deformity (HP:0001848)1.75389205
153Fibular aplasia (HP:0002990)1.75140214
154Muscular dystrophy (HP:0003560)1.74738533
155Abnormal finger flexion creases (HP:0006143)1.72331017
156Back pain (HP:0003418)1.71881091
157Aortic dissection (HP:0002647)1.67018544
158Striae distensae (HP:0001065)1.64138414
159Proximal amyotrophy (HP:0007126)1.62414108
160Polar cataract (HP:0010696)1.62158311
161Increased serum pyruvate (HP:0003542)1.61766882
162Abnormal EKG (HP:0003115)1.60966937
163Subcapsular cataract (HP:0000523)1.59709425

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TIE13.98229857
2BCKDK3.60286678
3SIK12.77629655
4INSRR2.58866852
5LMTK22.55034801
6TRIB32.11990141
7MST1R2.05355349
8FGFR42.04402665
9PDK32.02101081
10PDK42.02101081
11MYLK1.99557480
12MARK11.96178840
13OBSCN1.95138010
14KDR1.94308007
15FER1.87212949
16ERN11.87068324
17PHKG21.80716232
18PHKG11.80716232
19EPHB21.78941555
20PDK21.72067518
21GRK51.69904855
22DAPK21.64695079
23TTN1.57428755
24RIPK11.56710398
25MAPKAPK31.56530610
26GRK71.51019975
27NTRK11.47531938
28CAMK1D1.46511787
29TGFBR11.43976383
30MAPKAPK51.40955189
31MAP2K41.39751053
32PTK2B1.39055934
33TGFBR21.37971916
34MAP2K11.37672094
35LATS11.37099043
36FGFR21.32839841
37PIK3CA1.29948347
38PRKAA21.27099263
39EPHA31.26901987
40BMPR1B1.25192178
41EEF2K1.19334380
42DDR21.18210498
43MAP3K31.14325276
44MAPK121.11132618
45LATS21.07809373
46MAP3K21.06070270
47MAPK131.04989203
48CAMK1G1.02237126
49FRK1.01640139
50MAPK151.00405394
51PINK10.96743098
52EPHA40.96726643
53CDK80.93158964
54MOS0.91652442
55NEK90.91465642
56CCNB10.91243252
57PKN10.90951030
58GRK10.87339407
59NTRK30.86667797
60FGFR30.86229927
61STK38L0.80205918
62MAP3K70.79377808
63PRKD10.78341729
64RET0.78049635
65PKN20.73223465
66PRKCE0.72837521
67MAPK110.71659512
68PRKG10.71203927
69PIK3CG0.70255282
70PRKAA10.67733998
71AKT30.66733384
72PAK30.66032143
73MET0.65624286
74PRKACG0.64992317
75NLK0.63341882
76KSR20.61701152
77PDPK10.61594332
78SGK20.60653943
79JAK10.60212236
80PTK60.59297430
81ADRBK10.59111168
82IGF1R0.58554271
83STK240.57715339
84BCR0.57583777
85MAP3K10.57108791
86JAK20.57089783
87CDC42BPA0.56273249
88MAPK40.55755978
89PDGFRA0.55324358
90ERBB40.54611895
91MAP2K30.54246943
92PRKACB0.53633039
93MAP3K120.53201710
94CDK90.52153771
95MUSK0.51157813
96ABL20.50704409
97CAMK2A0.50630075
98TRPM70.49895883
99CAMK2G0.49640649
100CAMK2D0.49115267
101DMPK0.47612865
102LIMK10.47518184
103SGK30.46887555
104SGK2230.46705349
105SGK4940.46705349
106PRKCH0.46419683
107ERBB30.45458549
108AKT20.44406415
109GSK3A0.44307772
110PRKACA0.42724175
111RPS6KA30.42603479
112PTK20.42538273
113CAMK40.42346097
114CAMKK20.42066156
115ROCK10.42034592
116ROCK20.41844753
117PAK20.40949997
118CAMK2B0.40515883
119PRKG20.39156707
120CASK0.39110941
121PRKCZ0.37956787
122MINK10.37623272
123MAPK70.37111007
124EPHB10.36589084
125MAP3K40.36293927
126CAMK10.36141524
127MARK20.35406973
128MAP3K60.33149107
129IRAK10.31077486
130MTOR0.28367822
131STK110.27659281

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001203.32856771
2Fatty acid degradation_Homo sapiens_hsa000713.06644431
3Propanoate metabolism_Homo sapiens_hsa006402.99882818
4Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.85562688
5Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.77399925
6PPAR signaling pathway_Homo sapiens_hsa033202.63666342
7Fatty acid metabolism_Homo sapiens_hsa012122.54337909
8Nitrogen metabolism_Homo sapiens_hsa009102.53726013
9Arginine biosynthesis_Homo sapiens_hsa002202.44674984
10Tryptophan metabolism_Homo sapiens_hsa003802.39752697
11Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.32537248
12Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.29024612
13Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.25082301
142-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.13846508
15Complement and coagulation cascades_Homo sapiens_hsa046102.06482536
16Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.00038830
17Butanoate metabolism_Homo sapiens_hsa006501.95120198
18Phenylalanine metabolism_Homo sapiens_hsa003601.91318387
19Peroxisome_Homo sapiens_hsa041461.90742613
20Tyrosine metabolism_Homo sapiens_hsa003501.85002396
21Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.83137218
22Pyruvate metabolism_Homo sapiens_hsa006201.79729509
23Fatty acid elongation_Homo sapiens_hsa000621.71904766
24beta-Alanine metabolism_Homo sapiens_hsa004101.63508761
25Caffeine metabolism_Homo sapiens_hsa002321.62747255
26Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.55756123
27Bile secretion_Homo sapiens_hsa049761.46083783
28Histidine metabolism_Homo sapiens_hsa003401.44506436
29Chemical carcinogenesis_Homo sapiens_hsa052041.44125340
30Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.43176483
31Fatty acid biosynthesis_Homo sapiens_hsa000611.41276093
32Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.38345880
33Carbon metabolism_Homo sapiens_hsa012001.37633632
34Circadian rhythm_Homo sapiens_hsa047101.32828708
35Pentose and glucuronate interconversions_Homo sapiens_hsa000401.31424431
36Steroid hormone biosynthesis_Homo sapiens_hsa001401.25685875
37Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.22684717
38Fat digestion and absorption_Homo sapiens_hsa049751.20722639
39Retinol metabolism_Homo sapiens_hsa008301.19613967
40Staphylococcus aureus infection_Homo sapiens_hsa051501.18125367
41Glycerolipid metabolism_Homo sapiens_hsa005611.16501688
42Starch and sucrose metabolism_Homo sapiens_hsa005001.12286909
43Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.10895098
44Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.08905200
45Sulfur metabolism_Homo sapiens_hsa009201.04919454
46Focal adhesion_Homo sapiens_hsa045101.04522704
47Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.01887159
48ABC transporters_Homo sapiens_hsa020101.00868597
49Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.90097954
50Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.88163283
51Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.87612198
52Adipocytokine signaling pathway_Homo sapiens_hsa049200.87304248
53Oxidative phosphorylation_Homo sapiens_hsa001900.81494946
54Drug metabolism - other enzymes_Homo sapiens_hsa009830.74171572
55Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.71513675
56Insulin resistance_Homo sapiens_hsa049310.71149236
57Biosynthesis of amino acids_Homo sapiens_hsa012300.70023609
58Cardiac muscle contraction_Homo sapiens_hsa042600.69396220
59Parkinsons disease_Homo sapiens_hsa050120.68931499
60Alzheimers disease_Homo sapiens_hsa050100.67339227
61Glucagon signaling pathway_Homo sapiens_hsa049220.65762234
62Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.65703819
63Tight junction_Homo sapiens_hsa045300.64633408
64Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.63504190
65Arginine and proline metabolism_Homo sapiens_hsa003300.62144238
66Oxytocin signaling pathway_Homo sapiens_hsa049210.61216242
67Glycosaminoglycan degradation_Homo sapiens_hsa005310.59729371
68Adherens junction_Homo sapiens_hsa045200.55979552
69AMPK signaling pathway_Homo sapiens_hsa041520.55500050
70Lysine degradation_Homo sapiens_hsa003100.54316434
71Dilated cardiomyopathy_Homo sapiens_hsa054140.51645870
72Longevity regulating pathway - mammal_Homo sapiens_hsa042110.47898430
73Vitamin digestion and absorption_Homo sapiens_hsa049770.47577455
74Insulin signaling pathway_Homo sapiens_hsa049100.46163832
75Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.45303095
76Renin secretion_Homo sapiens_hsa049240.44860302
77Circadian entrainment_Homo sapiens_hsa047130.41991077
78Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.41967836
79Cysteine and methionine metabolism_Homo sapiens_hsa002700.41661045
80Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.41543336
81Selenocompound metabolism_Homo sapiens_hsa004500.39784330
82Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.36980674
83Metabolic pathways_Homo sapiens_hsa011000.36054848
84Folate biosynthesis_Homo sapiens_hsa007900.33638360
85Axon guidance_Homo sapiens_hsa043600.32082834
86Arachidonic acid metabolism_Homo sapiens_hsa005900.32023981
87Phospholipase D signaling pathway_Homo sapiens_hsa040720.30378736
88Ovarian steroidogenesis_Homo sapiens_hsa049130.29455467
89Glycerophospholipid metabolism_Homo sapiens_hsa005640.28792692
90PI3K-Akt signaling pathway_Homo sapiens_hsa041510.28742335
91Renin-angiotensin system_Homo sapiens_hsa046140.27932328
92Aldosterone synthesis and secretion_Homo sapiens_hsa049250.27508333
93Serotonergic synapse_Homo sapiens_hsa047260.27265414
94ECM-receptor interaction_Homo sapiens_hsa045120.26917617
95Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.26646850
96Protein digestion and absorption_Homo sapiens_hsa049740.26440077
97alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.26362517
98TGF-beta signaling pathway_Homo sapiens_hsa043500.26320780
99Vitamin B6 metabolism_Homo sapiens_hsa007500.25895842
100Proteoglycans in cancer_Homo sapiens_hsa052050.25636306
101Morphine addiction_Homo sapiens_hsa050320.25485004
102Gastric acid secretion_Homo sapiens_hsa049710.24672896
103Steroid biosynthesis_Homo sapiens_hsa001000.23263878
104Glutamatergic synapse_Homo sapiens_hsa047240.22976817
105Gap junction_Homo sapiens_hsa045400.22796957
106Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.21296199
107Huntingtons disease_Homo sapiens_hsa050160.20600367
108Glutathione metabolism_Homo sapiens_hsa004800.20542805
109Maturity onset diabetes of the young_Homo sapiens_hsa049500.19854580
110Pentose phosphate pathway_Homo sapiens_hsa000300.18768479
111Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.18696030
112Vascular smooth muscle contraction_Homo sapiens_hsa042700.17829412
113Prion diseases_Homo sapiens_hsa050200.17758333
114Calcium signaling pathway_Homo sapiens_hsa040200.17202510
115Cyanoamino acid metabolism_Homo sapiens_hsa004600.16417986
116Linoleic acid metabolism_Homo sapiens_hsa005910.16118750
117Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.14442923
118cGMP-PKG signaling pathway_Homo sapiens_hsa040220.14042744
119Salivary secretion_Homo sapiens_hsa049700.13851810
120Taste transduction_Homo sapiens_hsa047420.13371048
121Amoebiasis_Homo sapiens_hsa051460.13330335
122Fructose and mannose metabolism_Homo sapiens_hsa000510.11111082
123cAMP signaling pathway_Homo sapiens_hsa040240.10898290
124Dorso-ventral axis formation_Homo sapiens_hsa043200.09742888

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