Rank | Gene Set | Z-score |
---|---|---|
1 | cell wall macromolecule catabolic process (GO:0016998) | 4.58107470 |
2 | neural tube formation (GO:0001841) | 4.24610387 |
3 | cell wall macromolecule metabolic process (GO:0044036) | 3.96907752 |
4 | regulation of cilium movement (GO:0003352) | 3.95537885 |
5 | monoubiquitinated protein deubiquitination (GO:0035520) | 3.63351062 |
6 | fucose catabolic process (GO:0019317) | 3.62612731 |
7 | L-fucose metabolic process (GO:0042354) | 3.62612731 |
8 | L-fucose catabolic process (GO:0042355) | 3.62612731 |
9 | kinetochore organization (GO:0051383) | 3.49691369 |
10 | histone H3-K4 trimethylation (GO:0080182) | 3.48720547 |
11 | protein K11-linked deubiquitination (GO:0035871) | 3.47482207 |
12 | kinetochore assembly (GO:0051382) | 3.45804544 |
13 | interferon-gamma production (GO:0032609) | 3.18562311 |
14 | prenylation (GO:0097354) | 3.14827395 |
15 | protein prenylation (GO:0018342) | 3.14827395 |
16 | microtubule anchoring (GO:0034453) | 3.13571537 |
17 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.11681552 |
18 | cilium morphogenesis (GO:0060271) | 3.07593009 |
19 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 3.03324647 |
20 | double-strand break repair via homologous recombination (GO:0000724) | 3.01054401 |
21 | recombinational repair (GO:0000725) | 3.00687064 |
22 | regulation of telomere maintenance (GO:0032204) | 3.00385038 |
23 | DNA strand renaturation (GO:0000733) | 2.99678487 |
24 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.97237250 |
25 | regulation of hexokinase activity (GO:1903299) | 2.95803174 |
26 | regulation of glucokinase activity (GO:0033131) | 2.95803174 |
27 | histone H2A acetylation (GO:0043968) | 2.95080367 |
28 | pyrimidine nucleobase catabolic process (GO:0006208) | 2.94907388 |
29 | protein polyglutamylation (GO:0018095) | 2.93582104 |
30 | cell differentiation involved in metanephros development (GO:0072202) | 2.92272266 |
31 | microtubule depolymerization (GO:0007019) | 2.91537918 |
32 | indolalkylamine metabolic process (GO:0006586) | 2.90759990 |
33 | synapsis (GO:0007129) | 2.90620929 |
34 | behavioral response to nicotine (GO:0035095) | 2.89000337 |
35 | centriole replication (GO:0007099) | 2.87920383 |
36 | nonmotile primary cilium assembly (GO:0035058) | 2.87868734 |
37 | centriole assembly (GO:0098534) | 2.82238986 |
38 | platelet dense granule organization (GO:0060155) | 2.81234836 |
39 | limb bud formation (GO:0060174) | 2.81088153 |
40 | regulation of centriole replication (GO:0046599) | 2.78865605 |
41 | attachment of spindle microtubules to kinetochore (GO:0008608) | 2.77762313 |
42 | DNA demethylation (GO:0080111) | 2.77281800 |
43 | replication fork processing (GO:0031297) | 2.76477363 |
44 | superoxide anion generation (GO:0042554) | 2.73841750 |
45 | cilium organization (GO:0044782) | 2.72910796 |
46 | detection of light stimulus involved in sensory perception (GO:0050962) | 2.72361676 |
47 | detection of light stimulus involved in visual perception (GO:0050908) | 2.72361676 |
48 | photoreceptor cell maintenance (GO:0045494) | 2.71869929 |
49 | anterograde synaptic vesicle transport (GO:0048490) | 2.71305350 |
50 | cellular response to interleukin-15 (GO:0071350) | 2.70709556 |
51 | interkinetic nuclear migration (GO:0022027) | 2.70465112 |
52 | inositol phosphate catabolic process (GO:0071545) | 2.69841854 |
53 | establishment of protein localization to Golgi (GO:0072600) | 2.69673526 |
54 | cilium assembly (GO:0042384) | 2.69103790 |
55 | retinal cone cell development (GO:0046549) | 2.69066899 |
56 | ncRNA catabolic process (GO:0034661) | 2.68602196 |
57 | adaptation of signaling pathway (GO:0023058) | 2.65473012 |
58 | DNA methylation involved in gamete generation (GO:0043046) | 2.64515924 |
59 | polyol catabolic process (GO:0046174) | 2.64308574 |
60 | regulation of meiosis I (GO:0060631) | 2.63853344 |
61 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.63717998 |
62 | intraciliary transport (GO:0042073) | 2.63072468 |
63 | negative regulation of telomere maintenance (GO:0032205) | 2.62288460 |
64 | protein K6-linked ubiquitination (GO:0085020) | 2.60838877 |
65 | germinal center formation (GO:0002467) | 2.57005128 |
66 | male meiosis (GO:0007140) | 2.56381661 |
67 | positive regulation of interleukin-1 beta secretion (GO:0050718) | 2.55386878 |
68 | mesenchymal cell differentiation involved in renal system development (GO:2001012) | 2.54016626 |
69 | mesenchymal cell differentiation involved in kidney development (GO:0072161) | 2.54016626 |
70 | resolution of meiotic recombination intermediates (GO:0000712) | 2.53579801 |
71 | nucleobase catabolic process (GO:0046113) | 2.53426838 |
72 | female gonad development (GO:0008585) | 2.53291031 |
73 | myelin assembly (GO:0032288) | 2.53163040 |
74 | mast cell activation (GO:0045576) | 2.52976164 |
75 | response to pheromone (GO:0019236) | 2.52444917 |
76 | lymphoid progenitor cell differentiation (GO:0002320) | 2.52242913 |
77 | reciprocal meiotic recombination (GO:0007131) | 2.51757948 |
78 | reciprocal DNA recombination (GO:0035825) | 2.51757948 |
79 | histone H3-K36 demethylation (GO:0070544) | 2.50533488 |
80 | histone mRNA catabolic process (GO:0071044) | 2.50095390 |
81 | protein-cofactor linkage (GO:0018065) | 2.49741244 |
82 | negative T cell selection (GO:0043383) | 2.49352284 |
83 | regulation of DNA endoreduplication (GO:0032875) | 2.48738860 |
84 | negative regulation of DNA recombination (GO:0045910) | 2.48682537 |
85 | dendritic cell migration (GO:0036336) | 2.47973392 |
86 | dendritic cell chemotaxis (GO:0002407) | 2.47494646 |
87 | retinal ganglion cell axon guidance (GO:0031290) | 2.46403342 |
88 | chromatin remodeling at centromere (GO:0031055) | 2.46287055 |
89 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.45544902 |
90 | gene silencing by RNA (GO:0031047) | 2.45459177 |
91 | retinal rod cell development (GO:0046548) | 2.45285338 |
92 | reflex (GO:0060004) | 2.45242235 |
93 | photoreceptor cell development (GO:0042461) | 2.44984334 |
94 | acrosome assembly (GO:0001675) | 2.44935002 |
95 | regulation of MHC class II biosynthetic process (GO:0045346) | 2.44903141 |
96 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.44808975 |
97 | regulation of collateral sprouting (GO:0048670) | 2.43911963 |
98 | rRNA catabolic process (GO:0016075) | 2.43789710 |
99 | olfactory bulb development (GO:0021772) | 2.43693921 |
100 | regulation of alternative mRNA splicing, via spliceosome (GO:0000381) | 2.42796299 |
101 | regulation of microtubule-based movement (GO:0060632) | 2.41258265 |
102 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.41239961 |
103 | DNA ligation (GO:0006266) | 2.41155541 |
104 | lymph node development (GO:0048535) | 2.41066811 |
105 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.40666668 |
106 | somite rostral/caudal axis specification (GO:0032525) | 2.39766071 |
107 | protein targeting to Golgi (GO:0000042) | 2.39577174 |
108 | negative regulation of mast cell activation (GO:0033004) | 2.39513110 |
109 | phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) | 2.39206522 |
110 | regulation of timing of cell differentiation (GO:0048505) | 2.38584270 |
111 | regulation of sarcomere organization (GO:0060297) | 2.38268150 |
112 | cerebral cortex radially oriented cell migration (GO:0021799) | 2.38254018 |
113 | V(D)J recombination (GO:0033151) | 2.37857500 |
114 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.37806233 |
115 | phosphorylated carbohydrate dephosphorylation (GO:0046838) | 2.37068757 |
116 | inositol phosphate dephosphorylation (GO:0046855) | 2.37068757 |
117 | kynurenine metabolic process (GO:0070189) | 2.35655601 |
118 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.35393628 |
119 | piRNA metabolic process (GO:0034587) | 2.33676101 |
120 | regulation of B cell receptor signaling pathway (GO:0050855) | 2.32251233 |
121 | DNA double-strand break processing (GO:0000729) | 2.31786212 |
122 | negative thymic T cell selection (GO:0045060) | 2.31275789 |
123 | B cell homeostasis (GO:0001782) | 2.31085123 |
124 | positive regulation of interleukin-1 secretion (GO:0050716) | 2.28790367 |
125 | histone H3-K4 methylation (GO:0051568) | 2.28391399 |
126 | regulation of interleukin-1 beta secretion (GO:0050706) | 2.27857301 |
127 | dentate gyrus development (GO:0021542) | 2.27663167 |
128 | presynaptic membrane assembly (GO:0097105) | 2.26590998 |
129 | negative regulation of execution phase of apoptosis (GO:1900118) | 2.26037022 |
130 | NIK/NF-kappaB signaling (GO:0038061) | 2.25866019 |
131 | meiotic chromosome segregation (GO:0045132) | 2.25660855 |
132 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 2.23556150 |
133 | regulation of germinal center formation (GO:0002634) | 2.22413085 |
134 | regulation of T cell tolerance induction (GO:0002664) | 2.21330275 |
135 | presynaptic membrane organization (GO:0097090) | 2.19641933 |
136 | negative regulation of T cell mediated immunity (GO:0002710) | 2.19349256 |
137 | alpha-beta T cell differentiation (GO:0046632) | 2.19111177 |
138 | regulation of T cell receptor signaling pathway (GO:0050856) | 2.18921392 |
139 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.18782524 |
140 | replicative senescence (GO:0090399) | 2.18536333 |
141 | T cell homeostasis (GO:0043029) | 2.17752896 |
142 | energy homeostasis (GO:0097009) | 2.17232597 |
143 | radial glial cell differentiation (GO:0060019) | 2.17037691 |
144 | mature B cell differentiation (GO:0002335) | 2.16847104 |
145 | DNA synthesis involved in DNA repair (GO:0000731) | 2.16465864 |
146 | alpha-beta T cell activation (GO:0046631) | 2.16369532 |
147 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 2.16198116 |
148 | regulation of translation, ncRNA-mediated (GO:0045974) | 2.16198116 |
149 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 2.16198116 |
150 | positive regulation of interleukin-17 production (GO:0032740) | 2.14994640 |
151 | CD4-positive, alpha-beta T cell differentiation (GO:0043367) | 2.13982757 |
152 | protein localization to cilium (GO:0061512) | 2.13438948 |
153 | response to X-ray (GO:0010165) | 2.13167098 |
154 | T cell migration (GO:0072678) | 2.13046260 |
155 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 2.12669556 |
156 | T-helper cell differentiation (GO:0042093) | 2.12669556 |
157 | positive regulation of granulocyte differentiation (GO:0030854) | 2.10650750 |
158 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.09987912 |
159 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.09987912 |
160 | regulation of alpha-beta T cell proliferation (GO:0046640) | 2.09681935 |
161 | nuclear pore complex assembly (GO:0051292) | 2.09100312 |
162 | spinal cord motor neuron differentiation (GO:0021522) | 2.08522271 |
163 | retina layer formation (GO:0010842) | 2.08390503 |
164 | G-protein coupled receptor internalization (GO:0002031) | 2.08034714 |
165 | regulation of helicase activity (GO:0051095) | 2.06844826 |
166 | T cell differentiation (GO:0030217) | 2.06802737 |
167 | positive regulation of protein homodimerization activity (GO:0090073) | 2.05323105 |
168 | peptidyl-lysine trimethylation (GO:0018023) | 2.05091825 |
169 | inner ear receptor stereocilium organization (GO:0060122) | 2.04983462 |
170 | kidney morphogenesis (GO:0060993) | 2.04515437 |
171 | histamine secretion (GO:0001821) | 2.04444334 |
172 | positive regulation of interleukin-2 production (GO:0032743) | 2.04388005 |
173 | centrosome duplication (GO:0051298) | 2.03386272 |
174 | cell differentiation involved in kidney development (GO:0061005) | 2.03226664 |
175 | T cell selection (GO:0045058) | 2.02528670 |
176 | RNA destabilization (GO:0050779) | 2.02268828 |
177 | leukocyte aggregation (GO:0070486) | 2.02160861 |
178 | T cell differentiation involved in immune response (GO:0002292) | 2.02130046 |
179 | alpha-beta T cell differentiation involved in immune response (GO:0002293) | 2.02130046 |
180 | alpha-beta T cell activation involved in immune response (GO:0002287) | 2.02130046 |
181 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 2.01717709 |
182 | spleen development (GO:0048536) | 2.00768865 |
183 | intra-S DNA damage checkpoint (GO:0031573) | 2.00345486 |
184 | regulation of development, heterochronic (GO:0040034) | 1.99825678 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 4.18916559 |
2 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.49838813 |
3 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.47543305 |
4 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.16910636 |
5 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.67081576 |
6 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.60101285 |
7 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.59569494 |
8 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.51954925 |
9 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.36246685 |
10 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.33851894 |
11 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 2.31413805 |
12 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.25074457 |
13 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.18942959 |
14 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 2.17432428 |
15 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 2.13032951 |
16 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.09088173 |
17 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 2.05932288 |
18 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.01526165 |
19 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.99410733 |
20 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.98705310 |
21 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.96498333 |
22 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.95375701 |
23 | EWS_26573619_Chip-Seq_HEK293_Human | 1.94803803 |
24 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.91031990 |
25 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.90336139 |
26 | * BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.88245209 |
27 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.86737452 |
28 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.86457198 |
29 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.85505175 |
30 | P300_19829295_ChIP-Seq_ESCs_Human | 1.85024676 |
31 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.80626548 |
32 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.80545118 |
33 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.77695086 |
34 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.77539226 |
35 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.73384699 |
36 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.72286384 |
37 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.71899996 |
38 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.71638193 |
39 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.69995768 |
40 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.68152166 |
41 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.66115969 |
42 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.64038753 |
43 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 1.63242043 |
44 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.62910785 |
45 | FUS_26573619_Chip-Seq_HEK293_Human | 1.62430487 |
46 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.62224576 |
47 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.61738129 |
48 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.59556898 |
49 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.58089189 |
50 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.58089189 |
51 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.55147803 |
52 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 1.53709731 |
53 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.53382990 |
54 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.52590320 |
55 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.52075496 |
56 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.51361596 |
57 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.51272218 |
58 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.48813886 |
59 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.46961754 |
60 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.45194390 |
61 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.44235882 |
62 | PU1_27457419_Chip-Seq_LIVER_Mouse | 1.43210787 |
63 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.42930615 |
64 | * MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.42485438 |
65 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.42160968 |
66 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.40893468 |
67 | ZFX_18555785_Chip-Seq_ESCs_Mouse | 1.37907126 |
68 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 1.37858720 |
69 | AR_25329375_ChIP-Seq_VCAP_Human | 1.37501176 |
70 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.37223255 |
71 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.36391029 |
72 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.34855618 |
73 | CTCF_18555785_Chip-Seq_ESCs_Mouse | 1.34736046 |
74 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.33652749 |
75 | ESRRB_18555785_Chip-Seq_ESCs_Mouse | 1.32053608 |
76 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.32004963 |
77 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.31721633 |
78 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.31465173 |
79 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 1.31372784 |
80 | * OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.30692814 |
81 | * CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.30172822 |
82 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.27639994 |
83 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.26893471 |
84 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.26271712 |
85 | VDR_22108803_ChIP-Seq_LS180_Human | 1.25276048 |
86 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.24770652 |
87 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.24139694 |
88 | * TP53_22573176_ChIP-Seq_HFKS_Human | 1.23863532 |
89 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.23040566 |
90 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.21308566 |
91 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.20885150 |
92 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.20835157 |
93 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.20659632 |
94 | * FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.20487924 |
95 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.20021821 |
96 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.20021821 |
97 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.19009666 |
98 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.19009666 |
99 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.18820583 |
100 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.18616077 |
101 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.17857588 |
102 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.15739102 |
103 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.15341792 |
104 | * SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.15041897 |
105 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.14577435 |
106 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.13804295 |
107 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.12682409 |
108 | TCF4_23295773_ChIP-Seq_U87_Human | 1.12555601 |
109 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.11433939 |
110 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.10625296 |
111 | * PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.10396415 |
112 | * STAT3_23295773_ChIP-Seq_U87_Human | 1.09908884 |
113 | * PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.09542679 |
114 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.09382625 |
115 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.07599780 |
116 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.07288407 |
117 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.06478821 |
118 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.06436628 |
119 | * CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 1.06293846 |
120 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.06265955 |
121 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.06064516 |
122 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.04571863 |
123 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.04415186 |
124 | * TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.04154132 |
125 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.04042291 |
126 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.03469886 |
127 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.01941903 |
128 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.99931557 |
129 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 0.99353651 |
130 | * UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.97700173 |
131 | TP53_18474530_ChIP-ChIP_U2OS_Human | 0.97115107 |
132 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.97100452 |
133 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 0.96033234 |
134 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 0.95400384 |
135 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 0.94528671 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0001188_hyperpigmentation | 3.02267069 |
2 | MP0008057_abnormal_DNA_replication | 2.96945192 |
3 | MP0005409_darkened_coat_color | 2.85954738 |
4 | MP0006292_abnormal_olfactory_placode | 2.69169039 |
5 | MP0003195_calcinosis | 2.58244571 |
6 | MP0003787_abnormal_imprinting | 2.57188298 |
7 | MP0002163_abnormal_gland_morphology | 2.54714645 |
8 | MP0005551_abnormal_eye_electrophysiolog | 2.39407888 |
9 | MP0003136_yellow_coat_color | 2.29288756 |
10 | MP0003763_abnormal_thymus_physiology | 2.25494685 |
11 | MP0002837_dystrophic_cardiac_calcinosis | 2.25472196 |
12 | MP0005379_endocrine/exocrine_gland_phen | 2.20441591 |
13 | MP0008058_abnormal_DNA_repair | 2.17095798 |
14 | MP0008877_abnormal_DNA_methylation | 2.15955267 |
15 | MP0002009_preneoplasia | 2.12112261 |
16 | MP0001835_abnormal_antigen_presentation | 2.05214532 |
17 | MP0002277_abnormal_respiratory_mucosa | 2.03827985 |
18 | MP0010094_abnormal_chromosome_stability | 1.93862373 |
19 | MP0002102_abnormal_ear_morphology | 1.93052569 |
20 | MP0004147_increased_porphyrin_level | 1.89128569 |
21 | MP0005671_abnormal_response_to | 1.88725321 |
22 | MP0003941_abnormal_skin_development | 1.83450703 |
23 | MP0005253_abnormal_eye_physiology | 1.82516618 |
24 | MP0005646_abnormal_pituitary_gland | 1.76454572 |
25 | MP0009046_muscle_twitch | 1.72664538 |
26 | MP0000566_synostosis | 1.70104161 |
27 | MP0005171_absent_coat_pigmentation | 1.67754268 |
28 | MP0005387_immune_system_phenotype | 1.67733503 |
29 | MP0001790_abnormal_immune_system | 1.67733503 |
30 | MP0002396_abnormal_hematopoietic_system | 1.67169066 |
31 | MP0003011_delayed_dark_adaptation | 1.66988475 |
32 | MP0001346_abnormal_lacrimal_gland | 1.64556254 |
33 | MP0005645_abnormal_hypothalamus_physiol | 1.62544619 |
34 | MP0000015_abnormal_ear_pigmentation | 1.58149995 |
35 | MP0000427_abnormal_hair_cycle | 1.56012820 |
36 | MP0004381_abnormal_hair_follicle | 1.55902139 |
37 | MP0001486_abnormal_startle_reflex | 1.53965528 |
38 | MP0009745_abnormal_behavioral_response | 1.53365719 |
39 | MP0001485_abnormal_pinna_reflex | 1.52975568 |
40 | MP0008007_abnormal_cellular_replicative | 1.50827174 |
41 | MP0005386_behavior/neurological_phenoty | 1.50316546 |
42 | MP0004924_abnormal_behavior | 1.50316546 |
43 | MP0000569_abnormal_digit_pigmentation | 1.45263721 |
44 | MP0001800_abnormal_humoral_immune | 1.44975843 |
45 | MP0003718_maternal_effect | 1.40612432 |
46 | MP0002272_abnormal_nervous_system | 1.37671194 |
47 | MP0003111_abnormal_nucleus_morphology | 1.37549078 |
48 | MP0002751_abnormal_autonomic_nervous | 1.37401772 |
49 | MP0001501_abnormal_sleep_pattern | 1.37260686 |
50 | MP0008260_abnormal_autophagy | 1.36008908 |
51 | MP0003122_maternal_imprinting | 1.35909367 |
52 | MP0000516_abnormal_urinary_system | 1.33905192 |
53 | MP0005367_renal/urinary_system_phenotyp | 1.33905192 |
54 | MP0008789_abnormal_olfactory_epithelium | 1.33716443 |
55 | MP0008995_early_reproductive_senescence | 1.32972506 |
56 | MP0002148_abnormal_hypersensitivity_rea | 1.32397483 |
57 | MP0003786_premature_aging | 1.28042312 |
58 | MP0004885_abnormal_endolymph | 1.27182939 |
59 | MP0001293_anophthalmia | 1.26784244 |
60 | MP0001984_abnormal_olfaction | 1.26411916 |
61 | MP0002095_abnormal_skin_pigmentation | 1.25735708 |
62 | MP0001324_abnormal_eye_pigmentation | 1.25557630 |
63 | MP0004142_abnormal_muscle_tone | 1.23827187 |
64 | MP0005394_taste/olfaction_phenotype | 1.23229760 |
65 | MP0005499_abnormal_olfactory_system | 1.23229760 |
66 | MP0005000_abnormal_immune_tolerance | 1.22673861 |
67 | MP0003567_abnormal_fetal_cardiomyocyte | 1.22437684 |
68 | MP0001819_abnormal_immune_cell | 1.21925533 |
69 | MP0003121_genomic_imprinting | 1.21923779 |
70 | MP0002420_abnormal_adaptive_immunity | 1.21489920 |
71 | MP0009785_altered_susceptibility_to | 1.21410794 |
72 | MP0003880_abnormal_central_pattern | 1.20457908 |
73 | MP0002723_abnormal_immune_serum | 1.20302693 |
74 | MP0002398_abnormal_bone_marrow | 1.20291733 |
75 | MP0002452_abnormal_antigen_presenting | 1.18195661 |
76 | MP0000383_abnormal_hair_follicle | 1.15540852 |
77 | MP0003315_abnormal_perineum_morphology | 1.15487492 |
78 | MP0004215_abnormal_myocardial_fiber | 1.14455268 |
79 | MP0003077_abnormal_cell_cycle | 1.13338496 |
80 | MP0005310_abnormal_salivary_gland | 1.13190254 |
81 | MP0002067_abnormal_sensory_capabilities | 1.11157144 |
82 | MP0006276_abnormal_autonomic_nervous | 1.10201354 |
83 | MP0001986_abnormal_taste_sensitivity | 1.09559421 |
84 | MP0002572_abnormal_emotion/affect_behav | 1.07673415 |
85 | MP0002653_abnormal_ependyma_morphology | 1.06638012 |
86 | MP0000647_abnormal_sebaceous_gland | 1.06295659 |
87 | MP0004133_heterotaxia | 1.05388651 |
88 | MP0005174_abnormal_tail_pigmentation | 1.05133588 |
89 | MP0002405_respiratory_system_inflammati | 1.04490377 |
90 | MP0002557_abnormal_social/conspecific_i | 1.04231609 |
91 | MP0000716_abnormal_immune_system | 1.03750805 |
92 | MP0005195_abnormal_posterior_eye | 1.02832859 |
93 | MP0002234_abnormal_pharynx_morphology | 1.01614922 |
94 | MP0000703_abnormal_thymus_morphology | 0.99753562 |
95 | MP0000613_abnormal_salivary_gland | 0.99523651 |
96 | MP0001929_abnormal_gametogenesis | 0.99444461 |
97 | MP0006054_spinal_hemorrhage | 0.99266275 |
98 | MP0002736_abnormal_nociception_after | 0.98337885 |
99 | MP0002752_abnormal_somatic_nervous | 0.98057193 |
100 | MP0005451_abnormal_body_composition | 0.96567341 |
101 | MP0003698_abnormal_male_reproductive | 0.95754605 |
102 | MP0002160_abnormal_reproductive_system | 0.95523775 |
103 | MP0003890_abnormal_embryonic-extraembry | 0.95214658 |
104 | MP0000685_abnormal_immune_system | 0.95186517 |
105 | MP0006072_abnormal_retinal_apoptosis | 0.94540694 |
106 | MP0004808_abnormal_hematopoietic_stem | 0.94513979 |
107 | MP0002734_abnormal_mechanical_nocicepti | 0.93628216 |
108 | MP0004742_abnormal_vestibular_system | 0.93326558 |
109 | MP0002210_abnormal_sex_determination | 0.92728709 |
110 | MP0000631_abnormal_neuroendocrine_gland | 0.92449824 |
111 | MP0000372_irregular_coat_pigmentation | 0.92396270 |
112 | MP0008872_abnormal_physiological_respon | 0.92389182 |
113 | MP0003937_abnormal_limbs/digits/tail_de | 0.90475761 |
114 | MP0002876_abnormal_thyroid_physiology | 0.89251178 |
115 | MP0001119_abnormal_female_reproductive | 0.89190331 |
116 | MP0002006_tumorigenesis | 0.88919125 |
117 | MP0001186_pigmentation_phenotype | 0.88123800 |
118 | MP0000026_abnormal_inner_ear | 0.87891640 |
119 | MP0003828_pulmonary_edema | 0.86589469 |
120 | MP0002063_abnormal_learning/memory/cond | 0.86195720 |
121 | MP0000653_abnormal_sex_gland | 0.86076614 |
122 | MP0003119_abnormal_digestive_system | 0.85797840 |
123 | MP0005075_abnormal_melanosome_morpholog | 0.85659824 |
124 | MP0005391_vision/eye_phenotype | 0.85478134 |
125 | MP0003635_abnormal_synaptic_transmissio | 0.85140544 |
126 | MP0001529_abnormal_vocalization | 0.85019995 |
127 | MP0002064_seizures | 0.84922602 |
128 | MP0004270_analgesia | 0.84825084 |
129 | MP0002233_abnormal_nose_morphology | 0.84445010 |
130 | MP0001968_abnormal_touch/_nociception | 0.84052151 |
131 | MP0001919_abnormal_reproductive_system | 0.83772447 |
132 | MP0002938_white_spotting | 0.81682116 |
133 | MP0002132_abnormal_respiratory_system | 0.81025869 |
134 | MP0006035_abnormal_mitochondrial_morpho | 0.80381331 |
135 | MP0000778_abnormal_nervous_system | 0.80283166 |
136 | MP0002735_abnormal_chemical_nociception | 0.79970082 |
137 | MP0002928_abnormal_bile_duct | 0.79944668 |
138 | MP0009250_abnormal_appendicular_skeleto | 0.79552445 |
139 | MP0003693_abnormal_embryo_hatching | 0.79291419 |
140 | MP0005025_abnormal_response_to | 0.79096248 |
141 | MP0002638_abnormal_pupillary_reflex | 0.78844509 |
142 | MP0005389_reproductive_system_phenotype | 0.78843582 |
143 | MP0001145_abnormal_male_reproductive | 0.78318416 |
144 | MP0001286_abnormal_eye_development | 0.78021141 |
145 | MP0003724_increased_susceptibility_to | 0.77921532 |
146 | MP0002419_abnormal_innate_immunity | 0.77798815 |
147 | MP0009697_abnormal_copulation | 0.77738567 |
148 | MP0000049_abnormal_middle_ear | 0.76943073 |
149 | MP0002075_abnormal_coat/hair_pigmentati | 0.76907475 |
150 | MP0005248_abnormal_Harderian_gland | 0.76667763 |
151 | MP0002882_abnormal_neuron_morphology | 0.76459015 |
152 | MP0002722_abnormal_immune_system | 0.76134339 |
153 | MP0002229_neurodegeneration | 0.75485902 |
154 | MP0000689_abnormal_spleen_morphology | 0.75172949 |
155 | MP0002184_abnormal_innervation | 0.73784730 |
156 | MP0000955_abnormal_spinal_cord | 0.71848474 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 5.38102130 |
2 | Chromsome breakage (HP:0040012) | 5.10489300 |
3 | Pancreatic cysts (HP:0001737) | 4.01517015 |
4 | Molar tooth sign on MRI (HP:0002419) | 3.81531573 |
5 | Abnormality of midbrain morphology (HP:0002418) | 3.81531573 |
6 | Pancreatic fibrosis (HP:0100732) | 3.78736603 |
7 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 3.12647837 |
8 | Type II lissencephaly (HP:0007260) | 3.08248573 |
9 | Genital tract atresia (HP:0001827) | 3.08151223 |
10 | Lip pit (HP:0100267) | 3.05621588 |
11 | Volvulus (HP:0002580) | 3.04476663 |
12 | Abnormality of the preputium (HP:0100587) | 2.98429066 |
13 | Abnormality of the renal collecting system (HP:0004742) | 2.96094426 |
14 | Duplicated collecting system (HP:0000081) | 2.95337065 |
15 | Prostate neoplasm (HP:0100787) | 2.90983507 |
16 | Vaginal atresia (HP:0000148) | 2.88945601 |
17 | Hyperventilation (HP:0002883) | 2.83171007 |
18 | Meckel diverticulum (HP:0002245) | 2.79707588 |
19 | Congenital stationary night blindness (HP:0007642) | 2.75463703 |
20 | Abnormality of the renal cortex (HP:0011035) | 2.72761723 |
21 | Abnormality of chromosome stability (HP:0003220) | 2.68948029 |
22 | Progressive inability to walk (HP:0002505) | 2.64888618 |
23 | Abnormality of the ileum (HP:0001549) | 2.63841062 |
24 | Febrile seizures (HP:0002373) | 2.63786174 |
25 | Abnormality of DNA repair (HP:0003254) | 2.63673667 |
26 | Gaze-evoked nystagmus (HP:0000640) | 2.63341265 |
27 | Clubbing of toes (HP:0100760) | 2.62986002 |
28 | Chronic hepatic failure (HP:0100626) | 2.60909969 |
29 | Lissencephaly (HP:0001339) | 2.57679241 |
30 | Abnormal hair whorl (HP:0010721) | 2.56995261 |
31 | Ectopic kidney (HP:0000086) | 2.56464186 |
32 | Intestinal atresia (HP:0011100) | 2.46509383 |
33 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.42660895 |
34 | Inability to walk (HP:0002540) | 2.40349789 |
35 | Retinal dysplasia (HP:0007973) | 2.37839268 |
36 | Abnormality of the fingertips (HP:0001211) | 2.37719241 |
37 | Methylmalonic acidemia (HP:0002912) | 2.35630548 |
38 | Hypothermia (HP:0002045) | 2.34338389 |
39 | Retrobulbar optic neuritis (HP:0100654) | 2.31338617 |
40 | Optic neuritis (HP:0100653) | 2.31338617 |
41 | Absent/shortened dynein arms (HP:0200106) | 2.29931518 |
42 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.29931518 |
43 | Abnormality of the nasal septum (HP:0000419) | 2.25983127 |
44 | Abnormality of incisor morphology (HP:0011063) | 2.24470244 |
45 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.22690305 |
46 | Septo-optic dysplasia (HP:0100842) | 2.20960234 |
47 | Anencephaly (HP:0002323) | 2.19636964 |
48 | Attenuation of retinal blood vessels (HP:0007843) | 2.19463203 |
49 | Abnormality of the prostate (HP:0008775) | 2.17952588 |
50 | Upper limb muscle weakness (HP:0003484) | 2.17604298 |
51 | Neoplasm of the adrenal cortex (HP:0100641) | 2.15558825 |
52 | Broad-based gait (HP:0002136) | 2.14681618 |
53 | Drooling (HP:0002307) | 2.14674326 |
54 | Cystic liver disease (HP:0006706) | 2.14450868 |
55 | Renal cortical cysts (HP:0000803) | 2.13971410 |
56 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.13883572 |
57 | Eosinophilia (HP:0001880) | 2.12205637 |
58 | Nephronophthisis (HP:0000090) | 2.11627746 |
59 | Nephrogenic diabetes insipidus (HP:0009806) | 2.11418037 |
60 | Medial flaring of the eyebrow (HP:0010747) | 2.09560945 |
61 | Stomatitis (HP:0010280) | 2.08812831 |
62 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.08655204 |
63 | Embryonal renal neoplasm (HP:0011794) | 2.08411004 |
64 | Postaxial hand polydactyly (HP:0001162) | 2.06529608 |
65 | Obstructive lung disease (HP:0006536) | 2.06386709 |
66 | Chronic obstructive pulmonary disease (HP:0006510) | 2.06386709 |
67 | Agammaglobulinemia (HP:0004432) | 2.04849077 |
68 | Sclerocornea (HP:0000647) | 2.04625037 |
69 | Recurrent pneumonia (HP:0006532) | 2.04584848 |
70 | Autoimmune hemolytic anemia (HP:0001890) | 2.03566252 |
71 | Protruding tongue (HP:0010808) | 2.02897561 |
72 | Duodenal stenosis (HP:0100867) | 2.01146798 |
73 | Small intestinal stenosis (HP:0012848) | 2.01146798 |
74 | Tubulointerstitial nephritis (HP:0001970) | 2.00934058 |
75 | Abnormality of the columella (HP:0009929) | 2.00419691 |
76 | Cerebellar dysplasia (HP:0007033) | 1.99946582 |
77 | Dandy-Walker malformation (HP:0001305) | 1.99554915 |
78 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.98656906 |
79 | Excessive salivation (HP:0003781) | 1.98473457 |
80 | Acute myeloid leukemia (HP:0004808) | 1.97392392 |
81 | Narrow forehead (HP:0000341) | 1.96614022 |
82 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.96426390 |
83 | Stomach cancer (HP:0012126) | 1.95990132 |
84 | Abnormality of the carotid arteries (HP:0005344) | 1.95260674 |
85 | Tubular atrophy (HP:0000092) | 1.94705597 |
86 | White forelock (HP:0002211) | 1.93958385 |
87 | True hermaphroditism (HP:0010459) | 1.93911845 |
88 | Colon cancer (HP:0003003) | 1.93317307 |
89 | Oligodactyly (hands) (HP:0001180) | 1.93205814 |
90 | Congenital hepatic fibrosis (HP:0002612) | 1.90821748 |
91 | Abnormal biliary tract physiology (HP:0012439) | 1.89400782 |
92 | Bile duct proliferation (HP:0001408) | 1.89400782 |
93 | Specific learning disability (HP:0001328) | 1.89181243 |
94 | Median cleft lip (HP:0000161) | 1.88937230 |
95 | Abolished electroretinogram (ERG) (HP:0000550) | 1.88784707 |
96 | Recurrent fungal infections (HP:0002841) | 1.88468213 |
97 | Abnormality of eosinophils (HP:0001879) | 1.88443809 |
98 | Thyroiditis (HP:0100646) | 1.88298770 |
99 | Renal dysplasia (HP:0000110) | 1.87215682 |
100 | Myelodysplasia (HP:0002863) | 1.87046803 |
101 | Aplasia cutis congenita (HP:0001057) | 1.86728099 |
102 | Bone marrow hypocellularity (HP:0005528) | 1.86507938 |
103 | Abnormality of the renal medulla (HP:0100957) | 1.86240778 |
104 | Postaxial foot polydactyly (HP:0001830) | 1.85695440 |
105 | Osteomalacia (HP:0002749) | 1.85016798 |
106 | Furrowed tongue (HP:0000221) | 1.84942431 |
107 | Abnormality of alanine metabolism (HP:0010916) | 1.84885522 |
108 | Hyperalaninemia (HP:0003348) | 1.84885522 |
109 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.84885522 |
110 | Congenital primary aphakia (HP:0007707) | 1.84219737 |
111 | Panhypogammaglobulinemia (HP:0003139) | 1.83729362 |
112 | Gait imbalance (HP:0002141) | 1.83447670 |
113 | Gastrointestinal atresia (HP:0002589) | 1.82068443 |
114 | Sloping forehead (HP:0000340) | 1.79691491 |
115 | Optic nerve hypoplasia (HP:0000609) | 1.78969831 |
116 | Mesomelia (HP:0003027) | 1.78918571 |
117 | Abnormality of the incisor (HP:0000676) | 1.78693852 |
118 | Glioma (HP:0009733) | 1.78558771 |
119 | Bifid tongue (HP:0010297) | 1.77752103 |
120 | Meningitis (HP:0001287) | 1.77529787 |
121 | Poor coordination (HP:0002370) | 1.76502494 |
122 | Preaxial hand polydactyly (HP:0001177) | 1.76442169 |
123 | Granulocytopenia (HP:0001913) | 1.76396302 |
124 | Broad foot (HP:0001769) | 1.76385999 |
125 | Mediastinal lymphadenopathy (HP:0100721) | 1.75662140 |
126 | Methylmalonic aciduria (HP:0012120) | 1.75613694 |
127 | Duplication of thumb phalanx (HP:0009942) | 1.75312282 |
128 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.74710819 |
129 | Small hand (HP:0200055) | 1.73172149 |
130 | Abnormality of the labia minora (HP:0012880) | 1.72711423 |
131 | Recurrent sinusitis (HP:0011108) | 1.72019724 |
132 | Recurrent viral infections (HP:0004429) | 1.70769681 |
133 | Cupped ear (HP:0000378) | 1.70609057 |
134 | Labial hypoplasia (HP:0000066) | 1.70159924 |
135 | Leukocytosis (HP:0001974) | 1.69958726 |
136 | Abnormality of homocysteine metabolism (HP:0010919) | 1.69806418 |
137 | Homocystinuria (HP:0002156) | 1.69806418 |
138 | Fair hair (HP:0002286) | 1.69435806 |
139 | Chronic mucocutaneous candidiasis (HP:0002728) | 1.68915351 |
140 | Recurrent cutaneous fungal infections (HP:0011370) | 1.68915351 |
141 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.68893501 |
142 | Patchy hypopigmentation of hair (HP:0011365) | 1.68526184 |
143 | Severe combined immunodeficiency (HP:0004430) | 1.68162813 |
144 | Abnormal ciliary motility (HP:0012262) | 1.67931789 |
145 | Focal motor seizures (HP:0011153) | 1.67126735 |
146 | Astigmatism (HP:0000483) | 1.67123590 |
147 | Asplenia (HP:0001746) | 1.66372131 |
148 | Increased IgM level (HP:0003496) | 1.66203619 |
149 | Oligohydramnios (HP:0001562) | 1.65861089 |
150 | Multicystic kidney dysplasia (HP:0000003) | 1.65555767 |
151 | Pendular nystagmus (HP:0012043) | 1.65399236 |
152 | Constricted visual fields (HP:0001133) | 1.64838934 |
153 | Abnormality of T cell number (HP:0011839) | 1.64218262 |
154 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.64169362 |
155 | Chronic diarrhea (HP:0002028) | 1.64127079 |
156 | Short foot (HP:0001773) | 1.63391995 |
157 | Widely spaced teeth (HP:0000687) | 1.63305320 |
158 | Spinal cord lesions (HP:0100561) | 1.63243111 |
159 | Syringomyelia (HP:0003396) | 1.63243111 |
160 | Prominent nasal bridge (HP:0000426) | 1.63073461 |
161 | Progressive cerebellar ataxia (HP:0002073) | 1.62972438 |
162 | IgM deficiency (HP:0002850) | 1.62740992 |
163 | Triphalangeal thumb (HP:0001199) | 1.61451725 |
164 | Chorioretinal coloboma (HP:0000567) | 1.60721800 |
165 | Abnormality of the duodenum (HP:0002246) | 1.60161860 |
166 | Male pseudohermaphroditism (HP:0000037) | 1.59778544 |
167 | Abnormality of male internal genitalia (HP:0000022) | 1.58974984 |
168 | Aganglionic megacolon (HP:0002251) | 1.58790469 |
169 | Dyschromatopsia (HP:0007641) | 1.58720405 |
170 | Absent speech (HP:0001344) | 1.58096234 |
Rank | Gene Set | Z-score |
---|---|---|
1 | CASK | 4.10168144 |
2 | TXK | 3.44088851 |
3 | MAP4K2 | 3.35331866 |
4 | MAP3K14 | 2.40041560 |
5 | ZAK | 2.35235409 |
6 | TRIM28 | 2.35217585 |
7 | SIK3 | 2.29831640 |
8 | STK16 | 2.28643987 |
9 | MKNK2 | 2.10613610 |
10 | NEK1 | 2.01695783 |
11 | SRPK1 | 2.01597199 |
12 | CLK1 | 1.99091079 |
13 | ADRBK2 | 1.97517204 |
14 | TNIK | 1.92833803 |
15 | EIF2AK2 | 1.88650786 |
16 | IRAK4 | 1.83232440 |
17 | YES1 | 1.81962868 |
18 | BRD4 | 1.78974059 |
19 | BMPR2 | 1.77248358 |
20 | BRSK2 | 1.72680961 |
21 | MAP2K7 | 1.66926388 |
22 | EPHA3 | 1.66679441 |
23 | NUAK1 | 1.65782795 |
24 | NLK | 1.62856119 |
25 | INSRR | 1.60624868 |
26 | NEK6 | 1.51966138 |
27 | TAOK3 | 1.47496887 |
28 | PINK1 | 1.44151544 |
29 | PNCK | 1.40015265 |
30 | CDK3 | 1.38330491 |
31 | PAK3 | 1.37001838 |
32 | EPHA4 | 1.34879964 |
33 | TEC | 1.31596217 |
34 | BCR | 1.31266434 |
35 | MARK1 | 1.29248112 |
36 | SGK2 | 1.27658698 |
37 | MKNK1 | 1.23308404 |
38 | MAPK13 | 1.22514099 |
39 | IRAK1 | 1.21923633 |
40 | BMPR1B | 1.20873344 |
41 | FGFR2 | 1.17565592 |
42 | WEE1 | 1.15486925 |
43 | MAP4K1 | 1.14746554 |
44 | IRAK3 | 1.14443646 |
45 | PLK4 | 1.13565762 |
46 | PRPF4B | 1.11647066 |
47 | VRK1 | 1.10831160 |
48 | CHEK2 | 1.09882774 |
49 | IKBKB | 1.09261131 |
50 | AKT3 | 1.08627619 |
51 | OXSR1 | 1.07268827 |
52 | PLK2 | 1.07092452 |
53 | STK3 | 1.05866995 |
54 | MUSK | 1.05670859 |
55 | CDK8 | 1.04987501 |
56 | MAP3K12 | 1.04059509 |
57 | JAK3 | 1.02451576 |
58 | NTRK3 | 1.00061019 |
59 | CSNK1G1 | 0.96990846 |
60 | IKBKE | 0.96056206 |
61 | ATR | 0.94377631 |
62 | GRK7 | 0.93425992 |
63 | PKN1 | 0.93012200 |
64 | GRK1 | 0.91055966 |
65 | CDK12 | 0.90921882 |
66 | TNK2 | 0.90183765 |
67 | STK24 | 0.87252737 |
68 | TSSK6 | 0.84984798 |
69 | CSNK1G2 | 0.84417004 |
70 | CHUK | 0.82650719 |
71 | DYRK3 | 0.79668875 |
72 | RIPK4 | 0.79494984 |
73 | BTK | 0.79464327 |
74 | NEK2 | 0.79250865 |
75 | STK39 | 0.77330873 |
76 | STK38L | 0.76483000 |
77 | LCK | 0.75868425 |
78 | PLK3 | 0.75102811 |
79 | CAMKK2 | 0.73649028 |
80 | TGFBR1 | 0.72170976 |
81 | ITK | 0.70818712 |
82 | SYK | 0.69749802 |
83 | PRKCG | 0.69662153 |
84 | BUB1 | 0.67722519 |
85 | CSNK1G3 | 0.66997425 |
86 | TAOK2 | 0.65358881 |
87 | ACVR1B | 0.64842126 |
88 | CDK7 | 0.64821453 |
89 | TAF1 | 0.63561756 |
90 | PLK1 | 0.63442522 |
91 | PRKCQ | 0.63392094 |
92 | PRKCE | 0.63282358 |
93 | ERBB3 | 0.63049107 |
94 | MAP3K13 | 0.62014895 |
95 | SGK223 | 0.61106770 |
96 | SGK494 | 0.61106770 |
97 | ATM | 0.60305293 |
98 | FGFR3 | 0.58530989 |
99 | WNK4 | 0.58494039 |
100 | LYN | 0.58176717 |
101 | PRKD2 | 0.57140165 |
102 | IRAK2 | 0.55155211 |
103 | TLK1 | 0.54240144 |
104 | DAPK2 | 0.53662680 |
105 | TRPM7 | 0.53360042 |
106 | JAK1 | 0.52416478 |
107 | ADRBK1 | 0.51773784 |
108 | MAP3K4 | 0.51236856 |
109 | FER | 0.50978829 |
110 | TTK | 0.50645972 |
111 | STK4 | 0.50580565 |
112 | PASK | 0.50035051 |
113 | CHEK1 | 0.48364427 |
114 | MINK1 | 0.47158707 |
115 | HCK | 0.47146837 |
116 | SGK3 | 0.46549934 |
117 | KIT | 0.45868575 |
118 | FES | 0.44341414 |
119 | EIF2AK3 | 0.44242745 |
120 | CDC7 | 0.43751184 |
121 | RPS6KA5 | 0.43279181 |
122 | PIM1 | 0.42201959 |
123 | RPS6KA4 | 0.41753075 |
124 | CSNK1A1 | 0.41637332 |
125 | EPHB1 | 0.41350994 |
126 | MAPK7 | 0.39263659 |
127 | SGK1 | 0.39126328 |
128 | CSNK1D | 0.38965182 |
129 | STK11 | 0.38123352 |
130 | CAMK2A | 0.37940843 |
131 | DYRK2 | 0.37788355 |
132 | PIK3CA | 0.37642583 |
133 | MST4 | 0.37116110 |
134 | CSNK1A1L | 0.35821095 |
135 | CAMK2B | 0.34630823 |
136 | CSF1R | 0.34623364 |
137 | EIF2AK1 | 0.34615800 |
138 | CCNB1 | 0.34177251 |
139 | CDK1 | 0.33616347 |
140 | DYRK1A | 0.33157265 |
141 | PRKG1 | 0.32603009 |
142 | FRK | 0.32298339 |
143 | NTRK2 | 0.31974695 |
144 | KSR1 | 0.31078426 |
145 | FGFR1 | 0.31024715 |
146 | WNK3 | 0.30688260 |
147 | PRKAA1 | 0.30509224 |
148 | RPS6KB1 | 0.30494828 |
149 | LATS1 | 0.30441464 |
150 | PRKACB | 0.30384613 |
151 | PRKACA | 0.29173974 |
152 | MAP2K4 | 0.28762692 |
153 | OBSCN | 0.26574843 |
154 | CAMK4 | 0.25527815 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Selenocompound metabolism_Homo sapiens_hsa00450 | 2.90455848 |
2 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.87772309 |
3 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.81037975 |
4 | Protein export_Homo sapiens_hsa03060 | 2.75499715 |
5 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.42567198 |
6 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.27926850 |
7 | Allograft rejection_Homo sapiens_hsa05330 | 2.26114011 |
8 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.18265843 |
9 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.14820544 |
10 | Homologous recombination_Homo sapiens_hsa03440 | 2.06493247 |
11 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.97429321 |
12 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.92457315 |
13 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.86467645 |
14 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.86461557 |
15 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.86280451 |
16 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.84870951 |
17 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.78939606 |
18 | Mismatch repair_Homo sapiens_hsa03430 | 1.73215800 |
19 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.68952693 |
20 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.64662758 |
21 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.60622914 |
22 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.60318138 |
23 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.59970506 |
24 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.59203218 |
25 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.57364926 |
26 | Measles_Homo sapiens_hsa05162 | 1.54316918 |
27 | Basal transcription factors_Homo sapiens_hsa03022 | 1.52444284 |
28 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.47969764 |
29 | RNA degradation_Homo sapiens_hsa03018 | 1.46626709 |
30 | Asthma_Homo sapiens_hsa05310 | 1.40525423 |
31 | Nicotine addiction_Homo sapiens_hsa05033 | 1.39985092 |
32 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.38941983 |
33 | Phototransduction_Homo sapiens_hsa04744 | 1.38739786 |
34 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.34243989 |
35 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.34169204 |
36 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.33006011 |
37 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.31060864 |
38 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.28333985 |
39 | Cell cycle_Homo sapiens_hsa04110 | 1.26030752 |
40 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.24490255 |
41 | Circadian rhythm_Homo sapiens_hsa04710 | 1.22668466 |
42 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.22655510 |
43 | DNA replication_Homo sapiens_hsa03030 | 1.21714219 |
44 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.21361774 |
45 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.20924057 |
46 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.20421322 |
47 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.18658376 |
48 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.15171774 |
49 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.12334914 |
50 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.10673478 |
51 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.05190144 |
52 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.05162590 |
53 | Proteasome_Homo sapiens_hsa03050 | 1.04220269 |
54 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.02689949 |
55 | Leishmaniasis_Homo sapiens_hsa05140 | 1.02533267 |
56 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.01599151 |
57 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.00879980 |
58 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.99894454 |
59 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.99168826 |
60 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.95412813 |
61 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.95054789 |
62 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.94883809 |
63 | GABAergic synapse_Homo sapiens_hsa04727 | 0.94311502 |
64 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.91134316 |
65 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.91042600 |
66 | Long-term depression_Homo sapiens_hsa04730 | 0.89760157 |
67 | Circadian entrainment_Homo sapiens_hsa04713 | 0.89592278 |
68 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.88434045 |
69 | Influenza A_Homo sapiens_hsa05164 | 0.88376075 |
70 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.85766846 |
71 | ABC transporters_Homo sapiens_hsa02010 | 0.85007582 |
72 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.84958938 |
73 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.83102227 |
74 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.83035416 |
75 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.82668266 |
76 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.82484903 |
77 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.80466749 |
78 | RNA polymerase_Homo sapiens_hsa03020 | 0.79906661 |
79 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.79603049 |
80 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.78665408 |
81 | Peroxisome_Homo sapiens_hsa04146 | 0.77082982 |
82 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.76303757 |
83 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.76213639 |
84 | Insulin secretion_Homo sapiens_hsa04911 | 0.76001743 |
85 | Taste transduction_Homo sapiens_hsa04742 | 0.75713932 |
86 | Axon guidance_Homo sapiens_hsa04360 | 0.75683702 |
87 | Morphine addiction_Homo sapiens_hsa05032 | 0.74550362 |
88 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.74301082 |
89 | * mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.73986667 |
90 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.72583419 |
91 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.71256027 |
92 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.71118329 |
93 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.70574030 |
94 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.69713089 |
95 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.69683902 |
96 | Hepatitis B_Homo sapiens_hsa05161 | 0.68409393 |
97 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.67597233 |
98 | HTLV-I infection_Homo sapiens_hsa05166 | 0.66128646 |
99 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.62836900 |
100 | Melanoma_Homo sapiens_hsa05218 | 0.62755079 |
101 | Parkinsons disease_Homo sapiens_hsa05012 | 0.61549328 |
102 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.61119961 |
103 | Prostate cancer_Homo sapiens_hsa05215 | 0.60861705 |
104 | Spliceosome_Homo sapiens_hsa03040 | 0.60263524 |
105 | Malaria_Homo sapiens_hsa05144 | 0.59933162 |
106 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.59440103 |
107 | Base excision repair_Homo sapiens_hsa03410 | 0.58449201 |
108 | Olfactory transduction_Homo sapiens_hsa04740 | 0.58168114 |
109 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.57865359 |
110 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.57350098 |
111 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.54687312 |
112 | Tuberculosis_Homo sapiens_hsa05152 | 0.54403973 |
113 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.52252664 |
114 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.52103588 |
115 | Pathways in cancer_Homo sapiens_hsa05200 | 0.51467761 |
116 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.51317713 |
117 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.51306789 |
118 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.51248755 |
119 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.51163082 |
120 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.50876428 |
121 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.50800583 |
122 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.50532143 |
123 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.50475387 |
124 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.50350284 |
125 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.49994491 |
126 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.49436626 |
127 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.49430283 |
128 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.49214559 |
129 | Phagosome_Homo sapiens_hsa04145 | 0.49136742 |
130 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.47880841 |
131 | Huntingtons disease_Homo sapiens_hsa05016 | 0.46495439 |
132 | Alcoholism_Homo sapiens_hsa05034 | 0.44777281 |
133 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.43861666 |
134 | Colorectal cancer_Homo sapiens_hsa05210 | 0.43174532 |
135 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.43168165 |
136 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.43098694 |
137 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.42962059 |
138 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.42790877 |
139 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.42729116 |
140 | Salivary secretion_Homo sapiens_hsa04970 | 0.41940416 |
141 | RNA transport_Homo sapiens_hsa03013 | 0.41660697 |
142 | Purine metabolism_Homo sapiens_hsa00230 | 0.41393239 |
143 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.40656048 |
144 | Retinol metabolism_Homo sapiens_hsa00830 | 0.38283019 |
145 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.37474042 |
146 | Lysine degradation_Homo sapiens_hsa00310 | 0.37088909 |
147 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.35024980 |
148 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.34636544 |
149 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.33447760 |
150 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.33115514 |
151 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.32908295 |
152 | Metabolic pathways_Homo sapiens_hsa01100 | 0.31125631 |
153 | Legionellosis_Homo sapiens_hsa05134 | 0.30609808 |
154 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.28644725 |
155 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.28459056 |
156 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.25234025 |
157 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.24882172 |