PARD3B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1glomerular visceral epithelial cell development (GO:0072015)8.89593132
2glomerular basement membrane development (GO:0032836)8.45316434
3glomerulus development (GO:0032835)7.95154653
4glomerular epithelial cell development (GO:0072310)7.85348177
5polyketide metabolic process (GO:0030638)5.70163859
6doxorubicin metabolic process (GO:0044598)5.70163859
7daunorubicin metabolic process (GO:0044597)5.70163859
8pattern specification involved in kidney development (GO:0061004)5.30599394
9definitive hemopoiesis (GO:0060216)4.37536371
10epithelial cell differentiation involved in kidney development (GO:0035850)3.82775569
11metanephric mesenchyme development (GO:0072075)3.80536537
12venous blood vessel morphogenesis (GO:0048845)3.74731614
13aminoglycoside antibiotic metabolic process (GO:0030647)3.69313994
14mesonephros development (GO:0001823)3.60496769
15kidney mesenchyme development (GO:0072074)3.56048936
16cell differentiation involved in kidney development (GO:0061005)3.53026542
17collagen fibril organization (GO:0030199)3.38658680
18sequestering of extracellular ligand from receptor (GO:0035581)3.35081950
19paraxial mesoderm development (GO:0048339)3.29475059
20cell differentiation involved in metanephros development (GO:0072202)3.27299829
21mesenchymal cell differentiation involved in renal system development (GO:2001012)3.26099780
22mesenchymal cell differentiation involved in kidney development (GO:0072161)3.26099780
23positive regulation of vascular permeability (GO:0043117)3.23399178
24regulation of non-canonical Wnt signaling pathway (GO:2000050)3.12185548
25neuron projection extension involved in neuron projection guidance (GO:1902284)3.11590538
26axon extension involved in axon guidance (GO:0048846)3.11590538
27facial nerve structural organization (GO:0021612)3.06813771
28mesenchymal-epithelial cell signaling (GO:0060638)3.06499291
29negative regulation of keratinocyte proliferation (GO:0010839)3.02996328
30regulation of male gonad development (GO:2000018)3.01288485
31blood vessel maturation (GO:0001955)3.00211447
32radial glial cell differentiation (GO:0060019)2.99277609
33lymph vessel development (GO:0001945)2.98624248
34smooth muscle tissue development (GO:0048745)2.98596367
35regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.94954682
36negative regulation of protein localization to cell surface (GO:2000009)2.94614693
37negative regulation of osteoblast proliferation (GO:0033689)2.91637854
38vascular endothelial growth factor signaling pathway (GO:0038084)2.88762179
39establishment of planar polarity (GO:0001736)2.86536071
40establishment of tissue polarity (GO:0007164)2.86536071
41positive regulation of male gonad development (GO:2000020)2.85866855
42cell proliferation involved in metanephros development (GO:0072203)2.83874170
43regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.82649468
44lymphangiogenesis (GO:0001946)2.79767284
45ganglion development (GO:0061548)2.77322610
46artery development (GO:0060840)2.75991704
47positive regulation of p38MAPK cascade (GO:1900745)2.75274170
48mesenchymal cell differentiation (GO:0048762)2.74615438
49regulation of cell proliferation involved in kidney development (GO:1901722)2.73985236
50embryonic retina morphogenesis in camera-type eye (GO:0060059)2.71933917
51protein heterotrimerization (GO:0070208)2.71375960
52sprouting angiogenesis (GO:0002040)2.71181904
53regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.70183484
54lung vasculature development (GO:0060426)2.69054243
55exocrine pancreas development (GO:0031017)2.68562852
56endocardial cushion development (GO:0003197)2.68279730
57interkinetic nuclear migration (GO:0022027)2.67662982
58metanephric nephron tubule development (GO:0072234)2.67613909
59metanephric tubule development (GO:0072170)2.67613909
60lateral sprouting from an epithelium (GO:0060601)2.66051611
61ureteric bud development (GO:0001657)2.65994598
62prostate gland growth (GO:0060736)2.65062970
63regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307)2.63355730
64mesonephric tubule development (GO:0072164)2.62788502
65negative regulation of homotypic cell-cell adhesion (GO:0034111)2.62132338
66cell proliferation involved in kidney development (GO:0072111)2.61473474
67chondrocyte proliferation (GO:0035988)2.60073427
68appendage development (GO:0048736)2.59150765
69limb development (GO:0060173)2.59150765
70endothelium development (GO:0003158)2.59058708
71extracellular negative regulation of signal transduction (GO:1900116)2.58992396
72extracellular regulation of signal transduction (GO:1900115)2.58992396
73antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.58710573
74negative regulation of mesenchymal cell apoptotic process (GO:2001054)2.58709164
75detection of molecule of bacterial origin (GO:0032490)2.58426897
76energy homeostasis (GO:0097009)2.57346461
77regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.57337042
78mesenchymal cell development (GO:0014031)2.56839499
79extracellular matrix assembly (GO:0085029)2.56606285
80insulin-like growth factor receptor signaling pathway (GO:0048009)2.56450687
81negative regulation of axon extension involved in axon guidance (GO:0048843)2.55845474
82regulation of axon extension involved in axon guidance (GO:0048841)2.55712380
83segment specification (GO:0007379)2.55363202
84coronary vasculature morphogenesis (GO:0060977)2.54117127
85somite development (GO:0061053)2.53758291
86mesonephric epithelium development (GO:0072163)2.52941578
87metanephros development (GO:0001656)2.52666946
88metanephric epithelium development (GO:0072207)2.51142178
89auditory receptor cell stereocilium organization (GO:0060088)2.50478663
90surfactant homeostasis (GO:0043129)2.50222708
91regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.49811314
92neural crest cell development (GO:0014032)2.49725967
93mesenchyme morphogenesis (GO:0072132)2.49607113
94epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)2.47477144
95camera-type eye morphogenesis (GO:0048593)2.47132602
96negative chemotaxis (GO:0050919)2.47072835
97fibroblast migration (GO:0010761)2.46418399
98embryonic camera-type eye morphogenesis (GO:0048596)2.45746749
99regulation of integrin-mediated signaling pathway (GO:2001044)2.45010236
100positive regulation of respiratory burst (GO:0060267)2.40711249
101metanephric nephron epithelium development (GO:0072243)2.40246825
102negative regulation of axon guidance (GO:1902668)2.39858097
103hippo signaling (GO:0035329)2.39469584
104epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.37830881
105cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.37446686
106cell migration involved in heart development (GO:0060973)2.37018481
107regulation of female gonad development (GO:2000194)2.35630971
108regulation of keratinocyte proliferation (GO:0010837)2.35363961
109regulation of mesenchymal cell apoptotic process (GO:2001053)2.34985449
110axonal fasciculation (GO:0007413)2.34674806
111peripheral nervous system axon ensheathment (GO:0032292)2.34615561
112myelination in peripheral nervous system (GO:0022011)2.34615561
113cytoplasmic mRNA processing body assembly (GO:0033962)2.34138640
114regulation of axon guidance (GO:1902667)2.33843519
115platelet dense granule organization (GO:0060155)2.30526307
116diaphragm development (GO:0060539)2.30250623
117morphogenesis of an epithelial sheet (GO:0002011)2.30063643
118endosome to melanosome transport (GO:0035646)2.30045166
119endosome to pigment granule transport (GO:0043485)2.30045166
120stem cell development (GO:0048864)2.29058436
121cranial nerve structural organization (GO:0021604)2.28808211
122outer ear morphogenesis (GO:0042473)2.28072603
123extracellular fibril organization (GO:0043206)2.27995811
124retina vasculature morphogenesis in camera-type eye (GO:0061299)2.26700080
125regulation of p38MAPK cascade (GO:1900744)2.26363683
126bundle of His cell to Purkinje myocyte communication (GO:0086069)2.24979888
127phospholipid scrambling (GO:0017121)2.24875763
128regulation of mesenchymal cell proliferation (GO:0010464)2.24753576
129notochord development (GO:0030903)2.24468953
130renal filtration (GO:0097205)2.24294491
131positive regulation of cellular amide metabolic process (GO:0034250)2.23399306
132gland morphogenesis (GO:0022612)2.23297897
133renal tubule morphogenesis (GO:0061333)2.23224950
134negative regulation of fibroblast growth factor receptor signaling pathway (GO:0040037)2.23096425
135negative regulation of erythrocyte differentiation (GO:0045647)2.22713352
136mesodermal cell differentiation (GO:0048333)2.22340676
137dermatan sulfate biosynthetic process (GO:0030208)2.22318810
138negative regulation of platelet activation (GO:0010544)2.21745363
139peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)2.20951018
140positive regulation of mesenchymal cell proliferation (GO:0002053)2.20289480
141regulation of apoptotic process involved in morphogenesis (GO:1902337)2.19637057
142limb bud formation (GO:0060174)2.19478951
143cGMP-mediated signaling (GO:0019934)2.19422483
144sex determination (GO:0007530)2.19146033
145branching involved in salivary gland morphogenesis (GO:0060445)2.18566221
146axon extension (GO:0048675)2.18375233
147regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.18266091
148positive regulation of gastrulation (GO:2000543)2.17420042
149cardiac myofibril assembly (GO:0055003)2.16744200
150heart valve formation (GO:0003188)2.16553600
151negative regulation of chondrocyte differentiation (GO:0032331)2.15891540
152bone trabecula formation (GO:0060346)2.13834499
153presynaptic membrane assembly (GO:0097105)2.13412797
154nephron tubule development (GO:0072080)2.13032290
155cranial nerve morphogenesis (GO:0021602)2.12745952
156myoblast fusion (GO:0007520)2.12550882
157pericardium development (GO:0060039)2.12290936
158establishment of nucleus localization (GO:0040023)2.12034418
159cerebral cortex radially oriented cell migration (GO:0021799)2.11587924
160postsynaptic membrane organization (GO:0001941)2.09338395
161neuron recognition (GO:0008038)2.07831891
162proximal/distal pattern formation (GO:0009954)2.03916720
163cilium movement (GO:0003341)2.03428600
164negative regulation of stem cell proliferation (GO:2000647)2.02891736
165SMAD protein complex assembly (GO:0007183)2.01775136
166positive regulation of cartilage development (GO:0061036)2.01007583
167neuronal stem cell maintenance (GO:0097150)2.00799505
168dermatan sulfate metabolic process (GO:0030205)1.99663445
169astrocyte differentiation (GO:0048708)1.99314021
170presynaptic membrane organization (GO:0097090)1.98556539
171muscle cell migration (GO:0014812)1.97735052
172substrate adhesion-dependent cell spreading (GO:0034446)1.97611553
173mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337)1.97513684
174embryonic cranial skeleton morphogenesis (GO:0048701)1.97395910

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human2.91663901
2GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.89312095
3* GBX2_23144817_ChIP-Seq_PC3_Human2.52029499
4* CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.26705636
5IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.26025412
6CDX2_19796622_ChIP-Seq_MESCs_Mouse2.23429037
7HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.16945179
8SMAD_19615063_ChIP-ChIP_OVARY_Human2.16720803
9GATA2_21666600_ChIP-Seq_HMVEC_Human2.11816981
10WT1_19549856_ChIP-ChIP_CCG9911_Human2.08026064
11ESR1_22446102_ChIP-Seq_UTERUS_Mouse2.04796761
12PIAS1_25552417_ChIP-Seq_VCAP_Human2.04304771
13ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.02351090
14RBPJ_22232070_ChIP-Seq_NCS_Mouse1.98431382
15EED_16625203_ChIP-ChIP_MESCs_Mouse1.93765900
16ESR1_21235772_ChIP-Seq_MCF-7_Human1.92742788
17TRIM28_21343339_ChIP-Seq_HEK293_Human1.86079156
18EZH2_22144423_ChIP-Seq_EOC_Human1.81280140
19* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.77187290
20CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.74502356
21* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.72111897
22FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.68245805
23* STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.65134649
24PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.63342670
25* EP300_21415370_ChIP-Seq_HL-1_Mouse1.62441433
26* PCGF2_27294783_Chip-Seq_ESCs_Mouse1.59332157
27NRF2_20460467_ChIP-Seq_MEFs_Mouse1.58662377
28NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.58662377
29SCL_19346495_ChIP-Seq_HPC-7_Human1.57589091
30SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.56259920
31CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.53490996
32* ZFP57_27257070_Chip-Seq_ESCs_Mouse1.52281842
33FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.52214754
34RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.51983435
35TP63_19390658_ChIP-ChIP_HaCaT_Human1.51927411
36TCF4_18268006_ChIP-ChIP_LS174T_Human1.51257413
37AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.49862926
38* SUZ12_27294783_Chip-Seq_NPCs_Mouse1.49457915
39PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.49197963
40SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.46838532
41GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.45669445
42CJUN_26792858_Chip-Seq_BT549_Human1.45266536
43* SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.44889414
44* P300_19829295_ChIP-Seq_ESCs_Human1.44139473
45* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.44100447
46BMI1_23680149_ChIP-Seq_NPCS_Mouse1.43663031
47* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.41977260
48* PCGF2_27294783_Chip-Seq_NPCs_Mouse1.41829290
49SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.40795885
50CTBP2_25329375_ChIP-Seq_LNCAP_Human1.38872970
51SALL1_21062744_ChIP-ChIP_HESCs_Human1.38115387
52CBX2_27304074_Chip-Seq_ESCs_Mouse1.36471878
53* NFE2_27457419_Chip-Seq_LIVER_Mouse1.36349365
54EZH2_27304074_Chip-Seq_ESCs_Mouse1.36269398
55GATA1_22025678_ChIP-Seq_K562_Human1.36235269
56* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.35652042
57EZH2_18974828_ChIP-Seq_MESCs_Mouse1.34660318
58RNF2_18974828_ChIP-Seq_MESCs_Mouse1.34660318
59IRF8_22096565_ChIP-ChIP_GC-B_Human1.34175929
60CDX2_20551321_ChIP-Seq_CACO-2_Human1.32803368
61NR3C1_21868756_ChIP-Seq_MCF10A_Human1.31002014
62* TP53_18474530_ChIP-ChIP_U2OS_Human1.29216224
63TP53_16413492_ChIP-PET_HCT116_Human1.29201827
64* EZH2_27294783_Chip-Seq_NPCs_Mouse1.28421879
65ARNT_22903824_ChIP-Seq_MCF-7_Human1.27839829
66* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.27386727
67TP63_17297297_ChIP-ChIP_HaCaT_Human1.27349897
68* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.26869511
69* FLI1_27457419_Chip-Seq_LIVER_Mouse1.26693534
70* STAT3_23295773_ChIP-Seq_U87_Human1.26394991
71AR_21572438_ChIP-Seq_LNCaP_Human1.25832320
72AHR_22903824_ChIP-Seq_MCF-7_Human1.25394157
73JARID2_20075857_ChIP-Seq_MESCs_Mouse1.25338214
74* YAP1_20516196_ChIP-Seq_MESCs_Mouse1.25287192
75* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.24206270
76TAF15_26573619_Chip-Seq_HEK293_Human1.24175119
77PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.23745653
78ESR1_20079471_ChIP-ChIP_T-47D_Human1.23742601
79* SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.23371328
80MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.23155067
81SMAD3_21741376_ChIP-Seq_EPCs_Human1.22429517
82* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.21877064
83* SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.21853545
84FOXM1_26456572_ChIP-Seq_MCF-7_Human1.21592538
85* SMAD4_21799915_ChIP-Seq_A2780_Human1.21523949
86* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.20024032
87* ISL1_27105846_Chip-Seq_CPCs_Mouse1.19714161
88STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.18698243
89* JARID2_20064375_ChIP-Seq_MESCs_Mouse1.18503861
90TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.17622992
91CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.17006840
92* RING1B_27294783_Chip-Seq_ESCs_Mouse1.16691421
93BCAT_22108803_ChIP-Seq_LS180_Human1.16275690
94* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.16244566
95* NANOG_18555785_Chip-Seq_ESCs_Mouse1.16136047
96EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.15878897
97EWS_26573619_Chip-Seq_HEK293_Human1.14605689
98IGF1R_20145208_ChIP-Seq_DFB_Human1.14553062
99TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.13507924
100* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.13245070
101* RNF2_27304074_Chip-Seq_ESCs_Mouse1.12699658
102* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.12581426
103* E2F1_18555785_Chip-Seq_ESCs_Mouse1.11560073
104NR3C1_23031785_ChIP-Seq_PC12_Mouse1.11152812
105AR_25329375_ChIP-Seq_VCAP_Human1.10136746
106TP53_20018659_ChIP-ChIP_R1E_Mouse1.10073573
107CTBP1_25329375_ChIP-Seq_LNCAP_Human1.09086561
108RXR_22108803_ChIP-Seq_LS180_Human1.08720495
109CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.08677992
110* TCF4_23295773_ChIP-Seq_U87_Human1.08577380
111SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.08224649
112ESR2_21235772_ChIP-Seq_MCF-7_Human1.08112740
113BRD4_25478319_ChIP-Seq_HGPS_Human1.07498702
114SMAD3_21741376_ChIP-Seq_HESCs_Human1.07052327
115* P53_22387025_ChIP-Seq_ESCs_Mouse1.06852003
116* MTF2_20144788_ChIP-Seq_MESCs_Mouse1.06003127
117TBX3_20139965_ChIP-Seq_MESCs_Mouse1.05451884
118RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.05409901
119TBX3_20139965_ChIP-Seq_ESCs_Mouse1.05203872
120DROSHA_22980978_ChIP-Seq_HELA_Human1.04294947
121* EZH2_27294783_Chip-Seq_ESCs_Mouse1.04071826
122SOX9_24532713_ChIP-Seq_HFSC_Mouse1.03559891
123KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.02963191
124* CTNNB1_20460455_ChIP-Seq_HCT116_Human1.02696499
125FUS_26573619_Chip-Seq_HEK293_Human1.02673955
126ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.01964346
127SOX2_20726797_ChIP-Seq_SW620_Human1.01716107
128* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.01423184
129LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.01210080
130* SOX2_21211035_ChIP-Seq_LN229_Gbm1.00713772
131* STAT3_18555785_Chip-Seq_ESCs_Mouse1.00684281
132* SUZ12_18555785_Chip-Seq_ESCs_Mouse1.00647484
133EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.00563970
134* KDM2B_26808549_Chip-Seq_REH_Human1.00006010
135* RUNX2_22187159_ChIP-Seq_PCA_Human0.99468779
136RNF2_27304074_Chip-Seq_NSC_Mouse0.96882220
137* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.96718672

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000566_synostosis3.73771058
2MP0010368_abnormal_lymphatic_system3.62886629
3MP0005503_abnormal_tendon_morphology3.61313697
4MP0001879_abnormal_lymphatic_vessel3.05365583
5MP0004272_abnormal_basement_membrane2.88885840
6MP0003941_abnormal_skin_development2.76499684
7MP0008438_abnormal_cutaneous_collagen2.44664517
8MP0003279_aneurysm2.40390692
9MP0003705_abnormal_hypodermis_morpholog2.25983815
10MP0000516_abnormal_urinary_system2.18669387
11MP0005367_renal/urinary_system_phenotyp2.18669387
12MP0009384_cardiac_valve_regurgitation1.99560843
13MP0009780_abnormal_chondrocyte_physiolo1.95997481
14MP0002009_preneoplasia1.83086006
15MP0000778_abnormal_nervous_system1.76854879
16MP0003943_abnormal_hepatobiliary_system1.74637819
17MP0005275_abnormal_skin_tensile1.74579351
18MP0002938_white_spotting1.71577406
19MP0003942_abnormal_urinary_system1.71059123
20MP0009697_abnormal_copulation1.70779544
21MP0006292_abnormal_olfactory_placode1.69027779
22MP0000767_abnormal_smooth_muscle1.68073044
23MP0005377_hearing/vestibular/ear_phenot1.61932684
24MP0003878_abnormal_ear_physiology1.61932684
25MP0000678_abnormal_parathyroid_gland1.56356157
26MP0009250_abnormal_appendicular_skeleto1.55359003
27MP0001299_abnormal_eye_distance/1.50863887
28MP0002928_abnormal_bile_duct1.49293409
29MP0000049_abnormal_middle_ear1.47844663
30MP0010386_abnormal_urinary_bladder1.47554126
31MP0008004_abnormal_stomach_pH1.46615544
32MP0001188_hyperpigmentation1.46596873
33MP0003950_abnormal_plasma_membrane1.46057943
34MP0005508_abnormal_skeleton_morphology1.45603558
35MP0001958_emphysema1.40774396
36MP0004084_abnormal_cardiac_muscle1.37944897
37MP0002249_abnormal_larynx_morphology1.35568216
38MP0002653_abnormal_ependyma_morphology1.35395285
39MP0003283_abnormal_digestive_organ1.33687089
40MP0002295_abnormal_pulmonary_circulatio1.32983916
41MP0010030_abnormal_orbit_morphology1.32558196
42MP0005623_abnormal_meninges_morphology1.32154502
43MP0005220_abnormal_exocrine_pancreas1.31986177
44MP0006054_spinal_hemorrhage1.31899714
45MP0005595_abnormal_vascular_smooth1.31184417
46MP0000428_abnormal_craniofacial_morphol1.29399333
47MP0001542_abnormal_bone_strength1.28023161
48MP0001270_distended_abdomen1.26431637
49MP0000751_myopathy1.24665090
50MP0003385_abnormal_body_wall1.24065448
51MP0005171_absent_coat_pigmentation1.23025549
52MP0001346_abnormal_lacrimal_gland1.20961291
53MP0000579_abnormal_nail_morphology1.19320282
54MP0005670_abnormal_white_adipose1.19236822
55MP0005084_abnormal_gallbladder_morpholo1.19116604
56MP0000163_abnormal_cartilage_morphology1.19115550
57MP0002108_abnormal_muscle_morphology1.18045721
58MP0003755_abnormal_palate_morphology1.17563403
59MP0003935_abnormal_craniofacial_develop1.16118251
60MP0003136_yellow_coat_color1.16011629
61MP0009053_abnormal_anal_canal1.15499801
62MP0002277_abnormal_respiratory_mucosa1.15317151
63MP0005647_abnormal_sex_gland1.12185615
64MP0000613_abnormal_salivary_gland1.09745102
65MP0002128_abnormal_blood_circulation1.08305912
66MP0002166_altered_tumor_susceptibility1.08241628
67MP0003828_pulmonary_edema1.06881830
68MP0002132_abnormal_respiratory_system1.04713499
69MP0002115_abnormal_skeleton_extremities1.04238960
70MP0003091_abnormal_cell_migration1.03578724
71MP0002177_abnormal_outer_ear1.03147679
72MP0005646_abnormal_pituitary_gland1.02982779
73MP0003937_abnormal_limbs/digits/tail_de1.02952837
74MP0004808_abnormal_hematopoietic_stem1.01833947
75MP0001661_extended_life_span1.01655369
76MP0000762_abnormal_tongue_morphology1.00663395
77MP0003868_abnormal_feces_composition1.00006278
78MP0002109_abnormal_limb_morphology0.98526662
79MP0005409_darkened_coat_color0.97975377
80MP0005174_abnormal_tail_pigmentation0.97598227
81MP0003724_increased_susceptibility_to0.97548505
82MP0003045_fibrosis0.97387381
83MP0000749_muscle_degeneration0.97336913
84MP0002006_tumorigenesis0.97294715
85MP0001984_abnormal_olfaction0.96932306
86MP0000538_abnormal_urinary_bladder0.96195450
87MP0000534_abnormal_ureter_morphology0.95794993
88MP0002135_abnormal_kidney_morphology0.95664647
89MP0005248_abnormal_Harderian_gland0.94840582
90MP0002113_abnormal_skeleton_development0.93469069
91MP0003115_abnormal_respiratory_system0.92757167
92MP0008789_abnormal_olfactory_epithelium0.92267343
93MP0000230_abnormal_systemic_arterial0.91807986
94MP0000026_abnormal_inner_ear0.91490928
95MP0002998_abnormal_bone_remodeling0.91021543
96MP0002876_abnormal_thyroid_physiology0.90880451
97MP0002254_reproductive_system_inflammat0.90872960
98MP0000681_abnormal_thyroid_gland0.90606763
99MP0008995_early_reproductive_senescence0.90120306
100MP0003879_abnormal_hair_cell0.89495740
101MP0004134_abnormal_chest_morphology0.89462663
102MP0002282_abnormal_trachea_morphology0.89321486
103MP0002116_abnormal_craniofacial_bone0.88986086
104MP0002697_abnormal_eye_size0.88126024
105MP0002098_abnormal_vibrissa_morphology0.87278757
106MP0000733_abnormal_muscle_development0.87098841
107MP0003300_gastrointestinal_ulcer0.87071858
108MP0002932_abnormal_joint_morphology0.86924418
109MP0002233_abnormal_nose_morphology0.86694147
110MP0000383_abnormal_hair_follicle0.84900029
111MP0001286_abnormal_eye_development0.84491484
112MP0005620_abnormal_muscle_contractility0.83008787
113MP0002638_abnormal_pupillary_reflex0.82479839
114MP0002896_abnormal_bone_mineralization0.81813401
115MP0004133_heterotaxia0.81313158
116MP0004782_abnormal_surfactant_physiolog0.80674483
117MP0010352_gastrointestinal_tract_polyps0.80442629
118MP0000462_abnormal_digestive_system0.79888149
119MP0005257_abnormal_intraocular_pressure0.79858954
120MP0005167_abnormal_blood-brain_barrier0.79722364
121MP0002092_abnormal_eye_morphology0.79666475
122MP0006276_abnormal_autonomic_nervous0.79236260
123MP0003011_delayed_dark_adaptation0.79075899
124MP0006138_congestive_heart_failure0.78238908
125MP0001986_abnormal_taste_sensitivity0.77851407
126MP0000432_abnormal_head_morphology0.77552654
127MP0000372_irregular_coat_pigmentation0.77531159
128MP0005085_abnormal_gallbladder_physiolo0.77352615
129MP0002095_abnormal_skin_pigmentation0.76670546
130MP0002136_abnormal_kidney_physiology0.75883659
131MP0001293_anophthalmia0.75859071
132MP0002168_other_aberrant_phenotype0.75842282
133MP0002089_abnormal_postnatal_growth/wei0.75523944
134MP0003959_abnormal_lean_body0.74943257
135MP0002877_abnormal_melanocyte_morpholog0.74865687
136MP0002060_abnormal_skin_morphology0.74491079
137MP0003890_abnormal_embryonic-extraembry0.74209624
138MP0003566_abnormal_cell_adhesion0.73142049
139MP0005551_abnormal_eye_electrophysiolog0.72051627
140MP0005195_abnormal_posterior_eye0.71743391
141MP0000955_abnormal_spinal_cord0.71422133
142MP0005023_abnormal_wound_healing0.71420506
143MP0009379_abnormal_foot_pigmentation0.71188813
144MP0004858_abnormal_nervous_system0.70128883
145MP0000013_abnormal_adipose_tissue0.68963982
146MP0000631_abnormal_neuroendocrine_gland0.67522223
147MP0005197_abnormal_uvea_morphology0.66673719
148MP0002184_abnormal_innervation0.65712752
149MP0003252_abnormal_bile_duct0.65235823

Predicted human phenotypes

RankGene SetZ-score
1Mesangial abnormality (HP:0001966)5.73051466
2Protrusio acetabuli (HP:0003179)4.46125338
3Focal segmental glomerulosclerosis (HP:0000097)4.25905457
4Premature rupture of membranes (HP:0001788)3.89878986
5Vascular tortuosity (HP:0004948)3.72116566
6Neonatal short-limb short stature (HP:0008921)3.49277576
7Soft skin (HP:0000977)3.47209338
8Stage 5 chronic kidney disease (HP:0003774)3.25742072
9Arterial tortuosity (HP:0005116)3.23680143
10Pulmonary artery stenosis (HP:0004415)3.22846230
11True hermaphroditism (HP:0010459)3.21629383
12Hypoalbuminemia (HP:0003073)3.19848493
13Abnormal albumin level (HP:0012116)3.19848493
14Coronal craniosynostosis (HP:0004440)3.06296604
15Abnormality of the ischium (HP:0003174)3.00810575
16Glomerulosclerosis (HP:0000096)2.99807203
17Abnormality of the fingertips (HP:0001211)2.93246015
18Shallow orbits (HP:0000586)2.85662459
19Wide anterior fontanel (HP:0000260)2.81891643
20Hypoproteinemia (HP:0003075)2.75584888
21Broad metatarsal (HP:0001783)2.74382859
22Bladder diverticulum (HP:0000015)2.73332173
23Follicular hyperkeratosis (HP:0007502)2.72139290
24Hypoplastic ischia (HP:0003175)2.70584409
25Nephritis (HP:0000123)2.69955339
26Abnormality of dentin (HP:0010299)2.68213441
27Aortic regurgitation (HP:0001659)2.61260318
28Chronic hepatic failure (HP:0100626)2.59880731
29Overgrowth (HP:0001548)2.56909018
30Glomerulonephritis (HP:0000099)2.49616219
31Abnormality of incisor morphology (HP:0011063)2.49411393
32Tubulointerstitial nephritis (HP:0001970)2.41116669
33Tubular atrophy (HP:0000092)2.29190510
34Mitral valve prolapse (HP:0001634)2.28392077
35Type 1 muscle fiber predominance (HP:0003803)2.21871546
36Abnormality of the parietal bone (HP:0002696)2.21072030
37Midline defect of the nose (HP:0004122)2.20300883
38Renal cortical cysts (HP:0000803)2.18867555
39Asymmetry of the thorax (HP:0001555)2.16430535
40Ankle contracture (HP:0006466)2.14350941
41Hematochezia (HP:0002573)2.12895488
42Germ cell neoplasia (HP:0100728)2.12817329
43Ulnar bowing (HP:0003031)2.12532527
44Patchy hypopigmentation of hair (HP:0011365)2.11782703
45Occipital encephalocele (HP:0002085)2.11096070
46Renal dysplasia (HP:0000110)2.10668665
47White forelock (HP:0002211)2.10442663
48Hypothermia (HP:0002045)2.09515423
49Aortic aneurysm (HP:0004942)2.08604935
50Hyperextensible skin (HP:0000974)2.07592143
51Nasolacrimal duct obstruction (HP:0000579)2.07490668
52Cervical subluxation (HP:0003308)2.06856946
53Aortic valve stenosis (HP:0001650)2.06380235
54Wormian bones (HP:0002645)2.06286232
55Nonprogressive disorder (HP:0003680)2.04864387
56Absent frontal sinuses (HP:0002688)2.03448271
57Corneal erosion (HP:0200020)2.02283062
58Mitral stenosis (HP:0001718)2.02129779
59Abnormality of the nasal septum (HP:0000419)2.01398924
60Abnormality of the nasolacrimal system (HP:0000614)2.00652926
61Abnormality of the lacrimal duct (HP:0011481)2.00504307
62Mitral regurgitation (HP:0001653)1.99488912
63Infantile muscular hypotonia (HP:0008947)1.98919238
64Hip contracture (HP:0003273)1.97516164
65Vertebral arch anomaly (HP:0008438)1.97261206
66Portal hypertension (HP:0001409)1.91282808
67Pancreatic fibrosis (HP:0100732)1.90736169
68Aplasia cutis congenita (HP:0001057)1.90236127
69Subaortic stenosis (HP:0001682)1.89883080
70Abnormality of the left ventricular outflow tract (HP:0011103)1.89883080
71Lip pit (HP:0100267)1.88851176
72Abnormality of the renal cortex (HP:0011035)1.88369406
73Alveolar cell carcinoma (HP:0006519)1.88284336
74Prostate neoplasm (HP:0100787)1.87525808
75Craniofacial hyperostosis (HP:0004493)1.87519169
76Nephrotic syndrome (HP:0000100)1.87501818
77Cystic liver disease (HP:0006706)1.86734700
78Preaxial foot polydactyly (HP:0001841)1.84705200
79Aortic dissection (HP:0002647)1.84381939
80Ectopia lentis (HP:0001083)1.83816145
81Absent eyebrow (HP:0002223)1.83620973
82Rectal prolapse (HP:0002035)1.82814285
83Abnormality of the hepatic vasculature (HP:0006707)1.80468048
84Broad long bones (HP:0005622)1.79521076
85Lymphangioma (HP:0100764)1.79484228
86Joint laxity (HP:0001388)1.78921298
87Hypoplastic labia majora (HP:0000059)1.78053676
88Spinal rigidity (HP:0003306)1.77605171
89Bronchomalacia (HP:0002780)1.76626580
90Tibial bowing (HP:0002982)1.75739621
91Neoplasm of the lung (HP:0100526)1.74141594
92Anomalous pulmonary venous return (HP:0010772)1.73698721
93Turricephaly (HP:0000262)1.73202613
94Genu recurvatum (HP:0002816)1.72284738
95Tubulointerstitial abnormality (HP:0001969)1.70956471
96Tarsal synostosis (HP:0008368)1.70941569
97Synostosis involving bones of the lower limbs (HP:0009138)1.70173442
98Synostosis involving bones of the feet (HP:0009140)1.70173442
99Recurrent corneal erosions (HP:0000495)1.69865838
100Down-sloping shoulders (HP:0200021)1.68573083
101Abnormality of the pulmonary veins (HP:0011718)1.67753548
102Depressed nasal tip (HP:0000437)1.67624100
103Spontaneous hematomas (HP:0007420)1.67437688
104Enlarged penis (HP:0000040)1.67155499
105Intestinal atresia (HP:0011100)1.65580471
106Male pseudohermaphroditism (HP:0000037)1.65294716
107Prolonged bleeding time (HP:0003010)1.65025375
108Abnormality of the 4th metacarpal (HP:0010012)1.64940912
109Abnormality of the anterior chamber (HP:0000593)1.64255032
110Increased corneal curvature (HP:0100692)1.62584549
111Keratoconus (HP:0000563)1.62584549
112Pancreatic cysts (HP:0001737)1.62388788
113Increased number of teeth (HP:0011069)1.61825197
114Abnormality of the labia majora (HP:0012881)1.61576524
115Congenital sensorineural hearing impairment (HP:0008527)1.60777103
116Synostosis of carpal bones (HP:0005048)1.60766425
117Bowel diverticulosis (HP:0005222)1.59988428
118Cranial hyperostosis (HP:0004437)1.59743870
119Abnormality of the acetabulum (HP:0003170)1.59477050
120Hypoplastic left heart (HP:0004383)1.59371462
121Atrophic scars (HP:0001075)1.58887453
122Hypoplasia of the iris (HP:0007676)1.58401033
123Neoplasm of the tracheobronchial system (HP:0100552)1.58056122
124Abnormality of the renal medulla (HP:0100957)1.57937138
125Bell-shaped thorax (HP:0001591)1.57177609
126Aplasia involving bones of the extremities (HP:0009825)1.57091184
127Aplasia involving bones of the upper limbs (HP:0009823)1.57091184
128Aplasia of the phalanges of the hand (HP:0009802)1.57091184
129Broad phalanx (HP:0006009)1.57014121
130Atrial fibrillation (HP:0005110)1.56267136
131Abnormality of calcium-phosphate metabolism (HP:0100530)1.55939627
132Slender build (HP:0001533)1.55919994
133Proteinuria (HP:0000093)1.55666330
134Ulnar claw (HP:0001178)1.54411064
135Cutaneous finger syndactyly (HP:0010554)1.54155059
136Hematuria (HP:0000790)1.53987943
137Morphological abnormality of the middle ear (HP:0008609)1.52888306
138Limited hip movement (HP:0008800)1.52865803
139Congenital hepatic fibrosis (HP:0002612)1.52523538
140Abnormality of molar morphology (HP:0011070)1.52462464
141Abnormality of molar (HP:0011077)1.52462464
142Buphthalmos (HP:0000557)1.51311729
143Spondylolisthesis (HP:0003302)1.51166216
144Abnormal ciliary motility (HP:0012262)1.50989856
145Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.50968877
146Entropion (HP:0000621)1.50121724
147Biconcave vertebral bodies (HP:0004586)1.50081259
148Tracheomalacia (HP:0002779)1.48503978
149Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.48326107
150Cerebral aneurysm (HP:0004944)1.48253701
151Dilatation of the ascending aorta (HP:0005111)1.47844311
152Fragile skin (HP:0001030)1.47395374
153Flat cornea (HP:0007720)1.47278229
154Abnormality of the middle phalanges of the toes (HP:0010183)1.47120867
155Abnormality of the incisor (HP:0000676)1.46969038
156Chromosomal breakage induced by crosslinking agents (HP:0003221)1.46871424
157Osteomalacia (HP:0002749)1.46765714
158Aplasia/Hypoplasia of the tibia (HP:0005772)1.46451033
159Aneurysm (HP:0002617)1.46164269
160Cutaneous syndactyly (HP:0012725)1.46008181
161Pulmonic stenosis (HP:0001642)1.45544016
162Knee flexion contracture (HP:0006380)1.43795667
163Decreased circulating renin level (HP:0003351)1.43590688
164Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.43573171
165Nephropathy (HP:0000112)1.43556429
166Natal tooth (HP:0000695)1.43400724
167Laryngomalacia (HP:0001601)1.43396704
168Advanced eruption of teeth (HP:0006288)1.43296620
169Blue sclerae (HP:0000592)1.43187885
170Partial duplication of the phalanx of hand (HP:0009999)1.43130950
171Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.42980237
172Short 4th metacarpal (HP:0010044)1.42980237
173Genital tract atresia (HP:0001827)1.42554822
174Broad ribs (HP:0000885)1.42544450
175Xerostomia (HP:0000217)1.42076626
176Fibular hypoplasia (HP:0003038)1.41766514
177Nephronophthisis (HP:0000090)1.41692047
178Acute myeloid leukemia (HP:0004808)1.41420070
179Venous insufficiency (HP:0005293)1.41119522
180Medial flaring of the eyebrow (HP:0010747)1.40932909
181Camptodactyly of toe (HP:0001836)1.40823934

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TIE13.96406119
2FRK3.79901060
3LATS13.08274205
4TGFBR22.86906016
5INSRR2.84247155
6DDR22.57645605
7ZAK2.56022731
8NUAK12.55937181
9EPHA32.52131174
10MYLK2.30019930
11EPHB22.20573507
12LATS22.13142474
13PNCK1.99114212
14STK391.86020629
15IRAK31.77476378
16TGFBR11.73764407
17SIK11.71896703
18ERBB31.67275815
19FGFR21.55201238
20CDK81.55054459
21SIK31.52533993
22FGFR31.51884813
23NTRK11.51524103
24MAP3K141.51247287
25TNIK1.45549106
26PAK21.39058046
27SGK21.37619885
28NLK1.36435696
29MET1.35925495
30MUSK1.34922818
31TEC1.27760646
32MAPK151.27464692
33CHUK1.27457573
34PIK3CG1.26329698
35IRAK41.25447664
36LMTK21.25112663
37PDGFRB1.23744473
38KIT1.22832810
39MKNK21.21910424
40MARK11.21377322
41CASK1.21246737
42NEK91.19750008
43PIK3CA1.17963549
44CAMK1D1.17393325
45STK381.14371395
46PRKD31.13976999
47STK38L1.11768859
48EIF2AK21.09265506
49PTK21.09185556
50IRAK11.06205337
51STK31.02662951
52BRD41.00767352
53NTRK21.00178304
54CDK30.99929605
55TXK0.96623291
56TTN0.95630241
57YES10.92377152
58CAMK1G0.92187242
59RIPK10.92146531
60IKBKE0.92038760
61ADRBK10.91771314
62MOS0.89366853
63TAOK30.87460466
64PIM20.87076778
65JAK30.86392802
66SGK30.86196798
67MKNK10.86012498
68STK240.84011413
69NTRK30.82493227
70PINK10.82249541
71BMPR1B0.81857447
72GRK10.81790309
73MTOR0.79260283
74FGFR40.79153520
75PTK2B0.78738658
76MARK20.78217202
77ROCK20.76962130
78TRPM70.75095970
79IKBKB0.74438521
80DMPK0.73906224
81EPHA40.73881294
82WNK10.73731593
83PRKAA20.73155203
84MAP3K70.72809624
85ERN10.71496045
86PLK20.71471973
87WNK40.71431827
88CAMK2D0.70541626
89PAK30.70399969
90WNK30.69951540
91AKT30.68645869
92MAPK130.68355225
93PRKCE0.67651499
94ROCK10.66683772
95OBSCN0.66512845
96MELK0.65735802
97MAP3K40.65083011
98DYRK1B0.64232609
99FER0.63388524
100PAK40.63113848
101BMPR20.62711732
102ADRBK20.62149855
103CAMK40.61375919
104PRKG20.59083005
105PRKD20.58497220
106PDGFRA0.58241559
107RPS6KA20.57189167
108CAMK10.55829265
109JAK10.54433782
110IRAK20.51788816
111CAMK2G0.51587761
112GSK3A0.51053820
113PASK0.50237898
114PKN10.49238136
115CDK120.49219086
116CSNK1A1L0.49196751
117CAMK2B0.47864051
118MAP2K10.47844901
119PRKG10.47589527
120PTK60.47379575
121RPS6KA40.47088912
122PRKAA10.47051947
123BCR0.46923790
124EEF2K0.46693490
125BTK0.46470475
126CDK90.46184694
127NEK60.46157519
128IGF1R0.44298240
129MST1R0.44035344
130ERBB20.43430733
131CSNK1G10.43079479
132SGK4940.42879115
133SGK2230.42879115
134CDC42BPA0.42461089
135DAPK30.41918831
136PRKD10.41644993
137MATK0.41637496
138PHKG20.41056880
139PHKG10.41056880
140CAMK2A0.39764875
141FLT30.39325419
142KDR0.38898335
143RPS6KA60.37326292
144TBK10.36116118
145MAPK110.35071911
146MAPK70.33672991
147HIPK20.33487368
148PRPF4B0.32400396
149MAP2K60.31599795
150ACVR1B0.30819193
151MAPK30.30471951

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045123.10673368
2Protein digestion and absorption_Homo sapiens_hsa049742.37895781
3Maturity onset diabetes of the young_Homo sapiens_hsa049502.35626467
4Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.02965482
5Small cell lung cancer_Homo sapiens_hsa052221.92967276
6Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.85882393
7Focal adhesion_Homo sapiens_hsa045101.78011166
8Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.69965109
9Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.69233543
10AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.63868406
11Dilated cardiomyopathy_Homo sapiens_hsa054141.60795010
12NF-kappa B signaling pathway_Homo sapiens_hsa040641.57856898
13Primary bile acid biosynthesis_Homo sapiens_hsa001201.56464642
14Notch signaling pathway_Homo sapiens_hsa043301.56241050
15Arachidonic acid metabolism_Homo sapiens_hsa005901.52888542
16Transcriptional misregulation in cancer_Homo sapiens_hsa052021.51845481
17Other glycan degradation_Homo sapiens_hsa005111.49457798
18Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.48361245
19Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.47091010
20Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.45767687
21Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.44932949
22Adherens junction_Homo sapiens_hsa045201.43721995
23Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.39856879
24Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.37606763
25Vitamin digestion and absorption_Homo sapiens_hsa049771.37428637
26Tight junction_Homo sapiens_hsa045301.34471832
27Dorso-ventral axis formation_Homo sapiens_hsa043201.34361257
28Basal cell carcinoma_Homo sapiens_hsa052171.33484825
29Ovarian steroidogenesis_Homo sapiens_hsa049131.29885087
30Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.29232494
31TNF signaling pathway_Homo sapiens_hsa046681.28791419
32Amoebiasis_Homo sapiens_hsa051461.27306054
33Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.27262868
34Toll-like receptor signaling pathway_Homo sapiens_hsa046201.23781321
35PI3K-Akt signaling pathway_Homo sapiens_hsa041511.23572191
36Renin-angiotensin system_Homo sapiens_hsa046141.22912074
37Histidine metabolism_Homo sapiens_hsa003401.21499352
38Retinol metabolism_Homo sapiens_hsa008301.18914071
39Jak-STAT signaling pathway_Homo sapiens_hsa046301.18247662
40Melanoma_Homo sapiens_hsa052181.18097015
41Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.15350019
42Bile secretion_Homo sapiens_hsa049761.14372425
43Lysine degradation_Homo sapiens_hsa003101.13873531
44Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.13535736
45Hematopoietic cell lineage_Homo sapiens_hsa046401.13016665
46Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.11164454
47Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.10847197
48Chemical carcinogenesis_Homo sapiens_hsa052041.10636631
49NOD-like receptor signaling pathway_Homo sapiens_hsa046211.08253156
50Insulin secretion_Homo sapiens_hsa049111.07959606
51Prostate cancer_Homo sapiens_hsa052151.07253081
52Pathways in cancer_Homo sapiens_hsa052001.06886639
53Renin secretion_Homo sapiens_hsa049241.06346342
54Toxoplasmosis_Homo sapiens_hsa051451.03479117
55Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.02996398
56Complement and coagulation cascades_Homo sapiens_hsa046101.02964640
57Gap junction_Homo sapiens_hsa045401.02609167
58Glycosaminoglycan degradation_Homo sapiens_hsa005311.01813608
59Melanogenesis_Homo sapiens_hsa049161.00413930
60TGF-beta signaling pathway_Homo sapiens_hsa043500.98198775
61Circadian rhythm_Homo sapiens_hsa047100.98141504
62N-Glycan biosynthesis_Homo sapiens_hsa005100.97767931
63Herpes simplex infection_Homo sapiens_hsa051680.96848538
64Measles_Homo sapiens_hsa051620.95723959
65Platelet activation_Homo sapiens_hsa046110.95292864
66Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.94886607
67Starch and sucrose metabolism_Homo sapiens_hsa005000.94578575
68Tryptophan metabolism_Homo sapiens_hsa003800.94518031
69ABC transporters_Homo sapiens_hsa020100.92717274
70Leishmaniasis_Homo sapiens_hsa051400.91382379
71Circadian entrainment_Homo sapiens_hsa047130.88544072
72Axon guidance_Homo sapiens_hsa043600.88390079
73Linoleic acid metabolism_Homo sapiens_hsa005910.87622073
74Glutamatergic synapse_Homo sapiens_hsa047240.87429638
75Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.87368526
76RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.87129261
77Caffeine metabolism_Homo sapiens_hsa002320.86746177
78Cocaine addiction_Homo sapiens_hsa050300.86425116
79Aldosterone synthesis and secretion_Homo sapiens_hsa049250.86056262
80Intestinal immune network for IgA production_Homo sapiens_hsa046720.84559212
81Influenza A_Homo sapiens_hsa051640.83217109
82Sulfur metabolism_Homo sapiens_hsa009200.83175275
83Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.82656854
84Malaria_Homo sapiens_hsa051440.82565238
85Calcium signaling pathway_Homo sapiens_hsa040200.81781812
86Insulin resistance_Homo sapiens_hsa049310.80271759
87Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.79925137
88Butanoate metabolism_Homo sapiens_hsa006500.79626131
89Oxytocin signaling pathway_Homo sapiens_hsa049210.79390666
90Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.79342078
91Viral myocarditis_Homo sapiens_hsa054160.79326843
92Serotonergic synapse_Homo sapiens_hsa047260.79264613
93Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.78434522
94Fatty acid degradation_Homo sapiens_hsa000710.76962521
95Cholinergic synapse_Homo sapiens_hsa047250.76402906
96Hepatitis C_Homo sapiens_hsa051600.75861171
97Sphingolipid metabolism_Homo sapiens_hsa006000.75711497
98Fatty acid biosynthesis_Homo sapiens_hsa000610.75558316
99Osteoclast differentiation_Homo sapiens_hsa043800.75468026
100Proteoglycans in cancer_Homo sapiens_hsa052050.73719882
101Phototransduction_Homo sapiens_hsa047440.73503478
102Rap1 signaling pathway_Homo sapiens_hsa040150.72485521
103Salivary secretion_Homo sapiens_hsa049700.72300170
104Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.71747640
105Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.71135730
106Thyroid hormone synthesis_Homo sapiens_hsa049180.71085857
107Steroid hormone biosynthesis_Homo sapiens_hsa001400.70725436
108alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.70693747
109Nicotine addiction_Homo sapiens_hsa050330.70637932
110Nitrogen metabolism_Homo sapiens_hsa009100.69693788
111Propanoate metabolism_Homo sapiens_hsa006400.68689247
112Long-term depression_Homo sapiens_hsa047300.67249421
113Pancreatic cancer_Homo sapiens_hsa052120.66865270
114Arginine biosynthesis_Homo sapiens_hsa002200.66653157
115Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.65093455
116Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.64493412
117Acute myeloid leukemia_Homo sapiens_hsa052210.62728014
118Gastric acid secretion_Homo sapiens_hsa049710.62521470
119GABAergic synapse_Homo sapiens_hsa047270.62417827
120Sulfur relay system_Homo sapiens_hsa041220.62235054
121Wnt signaling pathway_Homo sapiens_hsa043100.61768429
122Hedgehog signaling pathway_Homo sapiens_hsa043400.61485281
123Taste transduction_Homo sapiens_hsa047420.61437413
124Endometrial cancer_Homo sapiens_hsa052130.61435758
125Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.61219048
126beta-Alanine metabolism_Homo sapiens_hsa004100.61144537
127Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.61112022
128Leukocyte transendothelial migration_Homo sapiens_hsa046700.58849428
129FoxO signaling pathway_Homo sapiens_hsa040680.57843783
130Ras signaling pathway_Homo sapiens_hsa040140.57649730
131MicroRNAs in cancer_Homo sapiens_hsa052060.56489574
132Mineral absorption_Homo sapiens_hsa049780.56217665
133SNARE interactions in vesicular transport_Homo sapiens_hsa041300.55426833
134Peroxisome_Homo sapiens_hsa041460.54535804
135Fat digestion and absorption_Homo sapiens_hsa049750.54508539
136Glycerolipid metabolism_Homo sapiens_hsa005610.54259592
137Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.54020323
138Regulation of actin cytoskeleton_Homo sapiens_hsa048100.53832183
139Prolactin signaling pathway_Homo sapiens_hsa049170.52356552
140cGMP-PKG signaling pathway_Homo sapiens_hsa040220.51548279
141Fanconi anemia pathway_Homo sapiens_hsa034600.50902568
142Pertussis_Homo sapiens_hsa051330.50235264
143PPAR signaling pathway_Homo sapiens_hsa033200.48542046
144cAMP signaling pathway_Homo sapiens_hsa040240.48360997
145Vascular smooth muscle contraction_Homo sapiens_hsa042700.47143258
146Pentose and glucuronate interconversions_Homo sapiens_hsa000400.46948913
147Staphylococcus aureus infection_Homo sapiens_hsa051500.46767583
148Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.46565917
149Pancreatic secretion_Homo sapiens_hsa049720.45915719
150Hippo signaling pathway_Homo sapiens_hsa043900.45438939
151African trypanosomiasis_Homo sapiens_hsa051430.44270389

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