

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | rRNA modification (GO:0000154) | 4.97124615 |
| 2 | rRNA methylation (GO:0031167) | 4.71106390 |
| 3 | CENP-A containing nucleosome assembly (GO:0034080) | 4.52811453 |
| 4 | regulation of centriole replication (GO:0046599) | 4.41199549 |
| 5 | chromatin remodeling at centromere (GO:0031055) | 4.40927903 |
| 6 | establishment of integrated proviral latency (GO:0075713) | 4.28680501 |
| 7 | histone exchange (GO:0043486) | 4.02527714 |
| 8 | DNA replication checkpoint (GO:0000076) | 4.01338334 |
| 9 | IMP biosynthetic process (GO:0006188) | 3.94791516 |
| 10 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.83259216 |
| 11 | DNA strand elongation (GO:0022616) | 3.73270111 |
| 12 | DNA ligation (GO:0006266) | 3.67050241 |
| 13 | DNA damage response, detection of DNA damage (GO:0042769) | 3.65760123 |
| 14 | ribosome assembly (GO:0042255) | 3.58162428 |
| 15 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.55005034 |
| 16 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.55005034 |
| 17 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.54956264 |
| 18 | nucleobase biosynthetic process (GO:0046112) | 3.50723358 |
| 19 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.49610416 |
| 20 | ATP synthesis coupled proton transport (GO:0015986) | 3.49610416 |
| 21 | DNA replication-independent nucleosome organization (GO:0034724) | 3.48978782 |
| 22 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.48978782 |
| 23 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.48696195 |
| 24 | termination of RNA polymerase III transcription (GO:0006386) | 3.48696195 |
| 25 | IMP metabolic process (GO:0046040) | 3.45288855 |
| 26 | mannosylation (GO:0097502) | 3.44882410 |
| 27 | spliceosomal snRNP assembly (GO:0000387) | 3.44792901 |
| 28 | chaperone-mediated protein transport (GO:0072321) | 3.39836606 |
| 29 | proteasome assembly (GO:0043248) | 3.38863636 |
| 30 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.36906000 |
| 31 | purine nucleobase biosynthetic process (GO:0009113) | 3.35781698 |
| 32 | DNA replication initiation (GO:0006270) | 3.34628550 |
| 33 | ribosomal small subunit assembly (GO:0000028) | 3.34486728 |
| 34 | establishment of viral latency (GO:0019043) | 3.33164316 |
| 35 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.28896533 |
| 36 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.28880514 |
| 37 | pseudouridine synthesis (GO:0001522) | 3.27864186 |
| 38 | maternal placenta development (GO:0001893) | 3.20772540 |
| 39 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.18296330 |
| 40 | lysine metabolic process (GO:0006553) | 3.17302923 |
| 41 | lysine catabolic process (GO:0006554) | 3.17302923 |
| 42 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.17278034 |
| 43 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.16240019 |
| 44 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.16240019 |
| 45 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.14288366 |
| 46 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.13990980 |
| 47 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.13364371 |
| 48 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.13364371 |
| 49 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.12265643 |
| 50 | negative regulation of ligase activity (GO:0051352) | 3.12265643 |
| 51 | mitotic sister chromatid segregation (GO:0000070) | 3.08226582 |
| 52 | protein neddylation (GO:0045116) | 3.08205373 |
| 53 | GTP biosynthetic process (GO:0006183) | 3.05645337 |
| 54 | mitochondrial RNA metabolic process (GO:0000959) | 3.05171555 |
| 55 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.04303902 |
| 56 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.03502867 |
| 57 | DNA unwinding involved in DNA replication (GO:0006268) | 3.02986752 |
| 58 | replication fork processing (GO:0031297) | 3.02739477 |
| 59 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.98417920 |
| 60 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.97779050 |
| 61 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.97779050 |
| 62 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.97779050 |
| 63 | non-recombinational repair (GO:0000726) | 2.97231620 |
| 64 | double-strand break repair via nonhomologous end joining (GO:0006303) | 2.97231620 |
| 65 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.95968431 |
| 66 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.94441815 |
| 67 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.94441815 |
| 68 | ATP-dependent chromatin remodeling (GO:0043044) | 2.92441514 |
| 69 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.90791769 |
| 70 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.90791769 |
| 71 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.88914337 |
| 72 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.88914337 |
| 73 | UTP metabolic process (GO:0046051) | 2.87707618 |
| 74 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 2.87393085 |
| 75 | transcription-coupled nucleotide-excision repair (GO:0006283) | 2.84481706 |
| 76 | protein localization to kinetochore (GO:0034501) | 2.83038416 |
| 77 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 2.82764738 |
| 78 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.81380669 |
| 79 | biotin metabolic process (GO:0006768) | 2.81023020 |
| 80 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 2.80329637 |
| 81 | tRNA aminoacylation for protein translation (GO:0006418) | 2.79049567 |
| 82 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.78928251 |
| 83 | 7-methylguanosine mRNA capping (GO:0006370) | 2.78345646 |
| 84 | UTP biosynthetic process (GO:0006228) | 2.78263207 |
| 85 | GPI anchor biosynthetic process (GO:0006506) | 2.77649087 |
| 86 | DNA deamination (GO:0045006) | 2.76996061 |
| 87 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.76799609 |
| 88 | tRNA aminoacylation (GO:0043039) | 2.76423389 |
| 89 | amino acid activation (GO:0043038) | 2.76423389 |
| 90 | iron-sulfur cluster assembly (GO:0016226) | 2.76390500 |
| 91 | metallo-sulfur cluster assembly (GO:0031163) | 2.76390500 |
| 92 | maturation of 5.8S rRNA (GO:0000460) | 2.75904946 |
| 93 | telomere maintenance via telomere lengthening (GO:0010833) | 2.75274439 |
| 94 | telomere maintenance via recombination (GO:0000722) | 2.74726276 |
| 95 | respiratory chain complex IV assembly (GO:0008535) | 2.74026347 |
| 96 | negative regulation of RNA splicing (GO:0033119) | 2.72122258 |
| 97 | regulation of helicase activity (GO:0051095) | 2.71640095 |
| 98 | formation of translation preinitiation complex (GO:0001731) | 2.71378180 |
| 99 | 7-methylguanosine RNA capping (GO:0009452) | 2.70926444 |
| 100 | RNA capping (GO:0036260) | 2.70926444 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 5.68370537 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.91023388 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.30099292 |
| 4 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.82585388 |
| 5 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.81337514 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.76496174 |
| 7 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.67368332 |
| 8 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.22796161 |
| 9 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.11401674 |
| 10 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.99655317 |
| 11 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.97478168 |
| 12 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.89380733 |
| 13 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.86866330 |
| 14 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.83967716 |
| 15 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.62772381 |
| 16 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.62567544 |
| 17 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.62473394 |
| 18 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.53263504 |
| 19 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.42949873 |
| 20 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.40231090 |
| 21 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.36308598 |
| 22 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.34495874 |
| 23 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.27576487 |
| 24 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.25827627 |
| 25 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.20840819 |
| 26 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.14280110 |
| 27 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.08763042 |
| 28 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 2.08641723 |
| 29 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.07252083 |
| 30 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.07078302 |
| 31 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.00784638 |
| 32 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.97409947 |
| 33 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.96317160 |
| 34 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.95607316 |
| 35 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.90517071 |
| 36 | VDR_22108803_ChIP-Seq_LS180_Human | 1.90356301 |
| 37 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.84898222 |
| 38 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.84856687 |
| 39 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.84666084 |
| 40 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.84658502 |
| 41 | EWS_26573619_Chip-Seq_HEK293_Human | 1.84013498 |
| 42 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.83247537 |
| 43 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.80457348 |
| 44 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.80270857 |
| 45 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.79184694 |
| 46 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.79117090 |
| 47 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.70466040 |
| 48 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.70246960 |
| 49 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.68401700 |
| 50 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.66783363 |
| 51 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.63785531 |
| 52 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.63761099 |
| 53 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.60238375 |
| 54 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.57490890 |
| 55 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.56037501 |
| 56 | FUS_26573619_Chip-Seq_HEK293_Human | 1.51819449 |
| 57 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.46892030 |
| 58 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.44335590 |
| 59 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.42279104 |
| 60 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.35959271 |
| 61 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.33493779 |
| 62 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.32843663 |
| 63 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.27056233 |
| 64 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.19146130 |
| 65 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.15243967 |
| 66 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.13764250 |
| 67 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.13439558 |
| 68 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.12850599 |
| 69 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.11236897 |
| 70 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.08707303 |
| 71 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.05076667 |
| 72 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.02938958 |
| 73 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.02210810 |
| 74 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.99462974 |
| 75 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.98248296 |
| 76 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.97334368 |
| 77 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 0.96084925 |
| 78 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.95533599 |
| 79 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.94716705 |
| 80 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.91088943 |
| 81 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.87731533 |
| 82 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.87504828 |
| 83 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.87322700 |
| 84 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.83482069 |
| 85 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.83272720 |
| 86 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.83214372 |
| 87 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.79404340 |
| 88 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.76818236 |
| 89 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.75598035 |
| 90 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.75559225 |
| 91 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.74441572 |
| 92 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.73828109 |
| 93 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.73616737 |
| 94 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.72806473 |
| 95 | P300_19829295_ChIP-Seq_ESCs_Human | 0.70990024 |
| 96 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.67555462 |
| 97 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.67538807 |
| 98 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.67206576 |
| 99 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.67203223 |
| 100 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.67070004 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0010094_abnormal_chromosome_stability | 4.80562116 |
| 2 | MP0008058_abnormal_DNA_repair | 4.59032064 |
| 3 | MP0003718_maternal_effect | 3.53022568 |
| 4 | MP0003111_abnormal_nucleus_morphology | 3.31858666 |
| 5 | MP0003693_abnormal_embryo_hatching | 3.08842770 |
| 6 | MP0003806_abnormal_nucleotide_metabolis | 2.94811956 |
| 7 | MP0006292_abnormal_olfactory_placode | 2.93582570 |
| 8 | MP0002102_abnormal_ear_morphology | 2.87703875 |
| 9 | MP0004957_abnormal_blastocyst_morpholog | 2.65248740 |
| 10 | MP0008877_abnormal_DNA_methylation | 2.55266361 |
| 11 | MP0003077_abnormal_cell_cycle | 2.40135176 |
| 12 | MP0001293_anophthalmia | 2.35678767 |
| 13 | MP0002938_white_spotting | 2.31079836 |
| 14 | MP0000372_irregular_coat_pigmentation | 2.29234837 |
| 15 | MP0001529_abnormal_vocalization | 2.20160994 |
| 16 | MP0000566_synostosis | 2.15769084 |
| 17 | MP0006072_abnormal_retinal_apoptosis | 2.09746431 |
| 18 | MP0003787_abnormal_imprinting | 1.86235396 |
| 19 | MP0006035_abnormal_mitochondrial_morpho | 1.80499639 |
| 20 | MP0008932_abnormal_embryonic_tissue | 1.80023182 |
| 21 | MP0002277_abnormal_respiratory_mucosa | 1.76058871 |
| 22 | MP0003786_premature_aging | 1.73152819 |
| 23 | MP0008057_abnormal_DNA_replication | 1.69971339 |
| 24 | MP0008007_abnormal_cellular_replicative | 1.61805852 |
| 25 | MP0006276_abnormal_autonomic_nervous | 1.60369197 |
| 26 | MP0009697_abnormal_copulation | 1.53941392 |
| 27 | MP0002160_abnormal_reproductive_system | 1.42338692 |
| 28 | MP0003121_genomic_imprinting | 1.41975529 |
| 29 | MP0002234_abnormal_pharynx_morphology | 1.38938436 |
| 30 | MP0003890_abnormal_embryonic-extraembry | 1.36161282 |
| 31 | MP0001730_embryonic_growth_arrest | 1.30657903 |
| 32 | MP0005389_reproductive_system_phenotype | 1.30651646 |
| 33 | MP0003119_abnormal_digestive_system | 1.30469245 |
| 34 | MP0005646_abnormal_pituitary_gland | 1.29736494 |
| 35 | MP0002751_abnormal_autonomic_nervous | 1.29491645 |
| 36 | MP0005253_abnormal_eye_physiology | 1.27768491 |
| 37 | MP0003937_abnormal_limbs/digits/tail_de | 1.24571447 |
| 38 | MP0008789_abnormal_olfactory_epithelium | 1.23499732 |
| 39 | MP0001929_abnormal_gametogenesis | 1.20047695 |
| 40 | MP0001919_abnormal_reproductive_system | 1.19718670 |
| 41 | MP0000579_abnormal_nail_morphology | 1.18521255 |
| 42 | MP0001145_abnormal_male_reproductive | 1.14961202 |
| 43 | MP0009672_abnormal_birth_weight | 1.14605428 |
| 44 | MP0010030_abnormal_orbit_morphology | 1.12290781 |
| 45 | MP0002210_abnormal_sex_determination | 1.10835233 |
| 46 | MP0006036_abnormal_mitochondrial_physio | 1.09227161 |
| 47 | MP0000653_abnormal_sex_gland | 1.07456755 |
| 48 | MP0008872_abnormal_physiological_respon | 1.07345427 |
| 49 | MP0005391_vision/eye_phenotype | 1.07004641 |
| 50 | MP0002837_dystrophic_cardiac_calcinosis | 1.06762716 |
| 51 | MP0000049_abnormal_middle_ear | 1.05809609 |
| 52 | MP0009379_abnormal_foot_pigmentation | 1.05704621 |
| 53 | MP0002163_abnormal_gland_morphology | 1.05495358 |
| 54 | MP0003195_calcinosis | 1.04413218 |
| 55 | MP0000350_abnormal_cell_proliferation | 1.02767564 |
| 56 | MP0002084_abnormal_developmental_patter | 1.02667033 |
| 57 | MP0002233_abnormal_nose_morphology | 1.01479349 |
| 58 | MP0003011_delayed_dark_adaptation | 1.00214086 |
| 59 | MP0003941_abnormal_skin_development | 1.00098711 |
| 60 | MP0005499_abnormal_olfactory_system | 0.99647545 |
| 61 | MP0005394_taste/olfaction_phenotype | 0.99647545 |
| 62 | MP0000313_abnormal_cell_death | 0.99390311 |
| 63 | MP0002085_abnormal_embryonic_tissue | 0.99371268 |
| 64 | MP0001485_abnormal_pinna_reflex | 0.98560421 |
| 65 | MP0001286_abnormal_eye_development | 0.97871110 |
| 66 | MP0001905_abnormal_dopamine_level | 0.95773514 |
| 67 | MP0002396_abnormal_hematopoietic_system | 0.95634755 |
| 68 | MP0002736_abnormal_nociception_after | 0.95221268 |
| 69 | MP0003315_abnormal_perineum_morphology | 0.94360777 |
| 70 | MP0003938_abnormal_ear_development | 0.94313412 |
| 71 | MP0002009_preneoplasia | 0.92258669 |
| 72 | MP0001697_abnormal_embryo_size | 0.92178896 |
| 73 | MP0000631_abnormal_neuroendocrine_gland | 0.90864644 |
| 74 | MP0001661_extended_life_span | 0.89487877 |
| 75 | MP0000358_abnormal_cell_content/ | 0.88892554 |
| 76 | MP0005395_other_phenotype | 0.88007267 |
| 77 | MP0003698_abnormal_male_reproductive | 0.87358012 |
| 78 | MP0000647_abnormal_sebaceous_gland | 0.87136928 |
| 79 | MP0002111_abnormal_tail_morphology | 0.85777881 |
| 80 | MP0003283_abnormal_digestive_organ | 0.85414337 |
| 81 | MP0003137_abnormal_impulse_conducting | 0.84646119 |
| 82 | MP0001672_abnormal_embryogenesis/_devel | 0.84472556 |
| 83 | MP0005380_embryogenesis_phenotype | 0.84472556 |
| 84 | MP0002697_abnormal_eye_size | 0.84063557 |
| 85 | MP0004197_abnormal_fetal_growth/weight/ | 0.83727809 |
| 86 | MP0004215_abnormal_myocardial_fiber | 0.83611381 |
| 87 | MP0004142_abnormal_muscle_tone | 0.81694999 |
| 88 | MP0001764_abnormal_homeostasis | 0.81451639 |
| 89 | MP0004742_abnormal_vestibular_system | 0.80980568 |
| 90 | MP0005551_abnormal_eye_electrophysiolog | 0.80207887 |
| 91 | MP0002092_abnormal_eye_morphology | 0.79537845 |
| 92 | MP0002080_prenatal_lethality | 0.79444658 |
| 93 | MP0002282_abnormal_trachea_morphology | 0.75145695 |
| 94 | MP0001346_abnormal_lacrimal_gland | 0.73646494 |
| 95 | MP0000537_abnormal_urethra_morphology | 0.73417378 |
| 96 | MP0004133_heterotaxia | 0.70969895 |
| 97 | MP0004782_abnormal_surfactant_physiolog | 0.70644419 |
| 98 | MP0001177_atelectasis | 0.68189338 |
| 99 | MP0001119_abnormal_female_reproductive | 0.63772163 |
| 100 | MP0001324_abnormal_eye_pigmentation | 0.63095706 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 3.59277043 |
| 2 | Abnormality of the labia minora (HP:0012880) | 3.54826030 |
| 3 | Acute encephalopathy (HP:0006846) | 3.45320260 |
| 4 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.23669967 |
| 5 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.19140878 |
| 6 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.19140878 |
| 7 | Hyperglycinemia (HP:0002154) | 3.12005345 |
| 8 | Increased CSF lactate (HP:0002490) | 3.03374856 |
| 9 | Increased hepatocellular lipid droplets (HP:0006565) | 3.01779207 |
| 10 | Mitochondrial inheritance (HP:0001427) | 2.97098597 |
| 11 | Increased serum pyruvate (HP:0003542) | 2.93053135 |
| 12 | Hyperglycinuria (HP:0003108) | 2.90368969 |
| 13 | Lipid accumulation in hepatocytes (HP:0006561) | 2.88619713 |
| 14 | Progressive macrocephaly (HP:0004481) | 2.83381215 |
| 15 | Hepatocellular necrosis (HP:0001404) | 2.81328465 |
| 16 | Carpal bone hypoplasia (HP:0001498) | 2.77107452 |
| 17 | Abnormality of glycolysis (HP:0004366) | 2.74806445 |
| 18 | Hypothermia (HP:0002045) | 2.73327363 |
| 19 | Abnormality of glycine metabolism (HP:0010895) | 2.63761372 |
| 20 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.63761372 |
| 21 | Methylmalonic acidemia (HP:0002912) | 2.60280251 |
| 22 | Abnormal number of erythroid precursors (HP:0012131) | 2.52765932 |
| 23 | Colon cancer (HP:0003003) | 2.50881280 |
| 24 | Cerebral edema (HP:0002181) | 2.45485790 |
| 25 | Type I transferrin isoform profile (HP:0003642) | 2.45349180 |
| 26 | Patellar aplasia (HP:0006443) | 2.44915139 |
| 27 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 2.42947053 |
| 28 | Hepatic necrosis (HP:0002605) | 2.41497988 |
| 29 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.41023979 |
| 30 | Increased serum lactate (HP:0002151) | 2.38350481 |
| 31 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.35085247 |
| 32 | Lactic acidosis (HP:0003128) | 2.33842643 |
| 33 | Abnormality of the preputium (HP:0100587) | 2.29277415 |
| 34 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 2.27757342 |
| 35 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.24620557 |
| 36 | Abnormality of serum amino acid levels (HP:0003112) | 2.24004573 |
| 37 | Leukodystrophy (HP:0002415) | 2.23748700 |
| 38 | Reticulocytopenia (HP:0001896) | 2.23646599 |
| 39 | Cerebral hypomyelination (HP:0006808) | 2.23387773 |
| 40 | Birth length less than 3rd percentile (HP:0003561) | 2.22817066 |
| 41 | Gout (HP:0001997) | 2.18815109 |
| 42 | Meckel diverticulum (HP:0002245) | 2.18424802 |
| 43 | Nephronophthisis (HP:0000090) | 2.15730304 |
| 44 | Abnormality of the prostate (HP:0008775) | 2.14081996 |
| 45 | Pancreatic cysts (HP:0001737) | 2.13136128 |
| 46 | Limb hypertonia (HP:0002509) | 2.12596396 |
| 47 | Abnormal protein glycosylation (HP:0012346) | 2.12285526 |
| 48 | Abnormal glycosylation (HP:0012345) | 2.12285526 |
| 49 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.12285526 |
| 50 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.12285526 |
| 51 | Lethargy (HP:0001254) | 2.12144721 |
| 52 | Inability to walk (HP:0002540) | 2.10319229 |
| 53 | Delayed CNS myelination (HP:0002188) | 2.10123775 |
| 54 | Increased intramyocellular lipid droplets (HP:0012240) | 2.08964187 |
| 55 | 3-Methylglutaconic aciduria (HP:0003535) | 2.08524833 |
| 56 | Shoulder girdle muscle weakness (HP:0003547) | 2.06694858 |
| 57 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.01992827 |
| 58 | Abnormality of methionine metabolism (HP:0010901) | 2.00350246 |
| 59 | Pancreatic fibrosis (HP:0100732) | 1.98897374 |
| 60 | Congenital, generalized hypertrichosis (HP:0004540) | 1.98823381 |
| 61 | Pendular nystagmus (HP:0012043) | 1.98439839 |
| 62 | Abnormality of the ileum (HP:0001549) | 1.98302303 |
| 63 | Renal Fanconi syndrome (HP:0001994) | 1.97675900 |
| 64 | Methylmalonic aciduria (HP:0012120) | 1.96580612 |
| 65 | Pancytopenia (HP:0001876) | 1.95505299 |
| 66 | Small intestinal stenosis (HP:0012848) | 1.92964294 |
| 67 | Duodenal stenosis (HP:0100867) | 1.92964294 |
| 68 | Microvesicular hepatic steatosis (HP:0001414) | 1.91885358 |
| 69 | Abolished electroretinogram (ERG) (HP:0000550) | 1.91423458 |
| 70 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.90744069 |
| 71 | Macrocytic anemia (HP:0001972) | 1.90552295 |
| 72 | Aplasia of the musculature (HP:0100854) | 1.90258117 |
| 73 | Abnormal biliary tract physiology (HP:0012439) | 1.89928108 |
| 74 | Bile duct proliferation (HP:0001408) | 1.89928108 |
| 75 | Aplastic anemia (HP:0001915) | 1.89264538 |
| 76 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.88624275 |
| 77 | Stenosis of the external auditory canal (HP:0000402) | 1.86963023 |
| 78 | Triphalangeal thumb (HP:0001199) | 1.86832916 |
| 79 | True hermaphroditism (HP:0010459) | 1.85134069 |
| 80 | Molar tooth sign on MRI (HP:0002419) | 1.84184380 |
| 81 | Abnormality of midbrain morphology (HP:0002418) | 1.84184380 |
| 82 | Degeneration of anterior horn cells (HP:0002398) | 1.82093717 |
| 83 | Abnormality of the anterior horn cell (HP:0006802) | 1.82093717 |
| 84 | Fibular aplasia (HP:0002990) | 1.80736636 |
| 85 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.79694334 |
| 86 | Abnormality of alanine metabolism (HP:0010916) | 1.79694334 |
| 87 | Hyperalaninemia (HP:0003348) | 1.79694334 |
| 88 | Multiple enchondromatosis (HP:0005701) | 1.79321871 |
| 89 | Epiphyseal stippling (HP:0010655) | 1.78255857 |
| 90 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.77788851 |
| 91 | Lissencephaly (HP:0001339) | 1.77282156 |
| 92 | Optic disc pallor (HP:0000543) | 1.76112336 |
| 93 | Megaloblastic anemia (HP:0001889) | 1.75587034 |
| 94 | Horseshoe kidney (HP:0000085) | 1.75566411 |
| 95 | Chromsome breakage (HP:0040012) | 1.74270222 |
| 96 | Oral leukoplakia (HP:0002745) | 1.71585064 |
| 97 | Abnormality of the hip-girdle musculature (HP:0001445) | 1.71455536 |
| 98 | Abnormality of the musculature of the pelvis (HP:0001469) | 1.71455536 |
| 99 | Septo-optic dysplasia (HP:0100842) | 1.70504115 |
| 100 | Sclerocornea (HP:0000647) | 1.70292639 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SRPK1 | 3.95590440 |
| 2 | BUB1 | 3.60518446 |
| 3 | VRK2 | 3.51914486 |
| 4 | CDC7 | 3.31613557 |
| 5 | TRIM28 | 2.88429731 |
| 6 | MKNK1 | 2.79529433 |
| 7 | PLK4 | 2.70817347 |
| 8 | EIF2AK3 | 2.70514800 |
| 9 | TSSK6 | 2.69525889 |
| 10 | STK16 | 2.38073963 |
| 11 | TNIK | 2.33372296 |
| 12 | TAF1 | 2.29614710 |
| 13 | TXK | 2.29107956 |
| 14 | ZAK | 2.16087617 |
| 15 | BCKDK | 2.09711682 |
| 16 | PLK3 | 2.06692475 |
| 17 | VRK1 | 2.02240541 |
| 18 | NEK1 | 1.93120655 |
| 19 | ERBB3 | 1.92381636 |
| 20 | MST4 | 1.86856369 |
| 21 | MKNK2 | 1.84511918 |
| 22 | NUAK1 | 1.80172668 |
| 23 | TTK | 1.75112628 |
| 24 | WNK3 | 1.66586602 |
| 25 | PASK | 1.65789233 |
| 26 | EIF2AK1 | 1.65125573 |
| 27 | BMPR1B | 1.64485955 |
| 28 | TLK1 | 1.50735112 |
| 29 | PNCK | 1.47504628 |
| 30 | PBK | 1.31042514 |
| 31 | MAP2K7 | 1.31024020 |
| 32 | BCR | 1.28936546 |
| 33 | ATR | 1.21181354 |
| 34 | PLK1 | 1.20474507 |
| 35 | CDK6 | 1.12945279 |
| 36 | BRSK2 | 1.09235609 |
| 37 | AURKB | 1.00478344 |
| 38 | KDR | 0.98941854 |
| 39 | CHEK2 | 0.98841012 |
| 40 | MAPKAPK5 | 0.96954278 |
| 41 | BRSK1 | 0.94694713 |
| 42 | NEK2 | 0.92656814 |
| 43 | CSNK1G1 | 0.92310479 |
| 44 | CSNK1G3 | 0.90983459 |
| 45 | EIF2AK2 | 0.90923585 |
| 46 | CDK9 | 0.80876372 |
| 47 | OXSR1 | 0.80283456 |
| 48 | CCNB1 | 0.79606994 |
| 49 | PLK2 | 0.77587370 |
| 50 | AURKA | 0.76526496 |
| 51 | SIK3 | 0.76443724 |
| 52 | RPS6KA4 | 0.75387106 |
| 53 | CSNK1G2 | 0.71083301 |
| 54 | NEK9 | 0.70387680 |
| 55 | MAP3K10 | 0.70213071 |
| 56 | CDK3 | 0.69136628 |
| 57 | DYRK2 | 0.67519987 |
| 58 | GRK1 | 0.66787212 |
| 59 | ALK | 0.66171675 |
| 60 | ATM | 0.61936612 |
| 61 | TGFBR1 | 0.61598892 |
| 62 | WEE1 | 0.61188904 |
| 63 | CSNK2A1 | 0.60089100 |
| 64 | PHKG2 | 0.60019795 |
| 65 | PHKG1 | 0.60019795 |
| 66 | ADRBK2 | 0.58070749 |
| 67 | GRK5 | 0.53632620 |
| 68 | RPS6KB2 | 0.53265274 |
| 69 | CSNK2A2 | 0.52938328 |
| 70 | MAP3K4 | 0.52647072 |
| 71 | MINK1 | 0.50157124 |
| 72 | RPS6KA5 | 0.49937613 |
| 73 | CHEK1 | 0.49832315 |
| 74 | CSNK1A1L | 0.48491098 |
| 75 | SMG1 | 0.48387133 |
| 76 | CDK4 | 0.48122896 |
| 77 | FRK | 0.47828916 |
| 78 | LMTK2 | 0.43767992 |
| 79 | ERBB4 | 0.43020923 |
| 80 | STK39 | 0.42811916 |
| 81 | CSNK1E | 0.40044421 |
| 82 | CDK7 | 0.39195381 |
| 83 | DAPK1 | 0.38927269 |
| 84 | CDK2 | 0.38608774 |
| 85 | CDK1 | 0.32990542 |
| 86 | NME1 | 0.30314860 |
| 87 | KIT | 0.29469099 |
| 88 | BRD4 | 0.29001496 |
| 89 | TESK2 | 0.28291232 |
| 90 | TIE1 | 0.28152207 |
| 91 | CDK19 | 0.27949046 |
| 92 | PRKCG | 0.27093925 |
| 93 | CDK18 | 0.23772727 |
| 94 | TEC | 0.23505333 |
| 95 | FGFR2 | 0.23188303 |
| 96 | INSRR | 0.22569575 |
| 97 | PRKDC | 0.20925445 |
| 98 | PRKACB | 0.19780567 |
| 99 | MAPK13 | 0.19479751 |
| 100 | CSNK1A1 | 0.19317448 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA replication_Homo sapiens_hsa03030 | 3.71573508 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 3.70096377 |
| 3 | Mismatch repair_Homo sapiens_hsa03430 | 3.16921674 |
| 4 | RNA polymerase_Homo sapiens_hsa03020 | 3.04711831 |
| 5 | Base excision repair_Homo sapiens_hsa03410 | 2.68825764 |
| 6 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.67068165 |
| 7 | Basal transcription factors_Homo sapiens_hsa03022 | 2.64561621 |
| 8 | Protein export_Homo sapiens_hsa03060 | 2.54025032 |
| 9 | Spliceosome_Homo sapiens_hsa03040 | 2.44653248 |
| 10 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.44281169 |
| 11 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.37811689 |
| 12 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.32911906 |
| 13 | Steroid biosynthesis_Homo sapiens_hsa00100 | 2.31682014 |
| 14 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.27766593 |
| 15 | Ribosome_Homo sapiens_hsa03010 | 2.22918231 |
| 16 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 2.21015451 |
| 17 | Homologous recombination_Homo sapiens_hsa03440 | 2.16872842 |
| 18 | RNA transport_Homo sapiens_hsa03013 | 2.09402813 |
| 19 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.09034187 |
| 20 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.97175427 |
| 21 | Parkinsons disease_Homo sapiens_hsa05012 | 1.95938189 |
| 22 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.91243408 |
| 23 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.80764596 |
| 24 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.76313324 |
| 25 | RNA degradation_Homo sapiens_hsa03018 | 1.75078444 |
| 26 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.66580304 |
| 27 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.64468764 |
| 28 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.59606141 |
| 29 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.55242522 |
| 30 | Cell cycle_Homo sapiens_hsa04110 | 1.52859096 |
| 31 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.51516121 |
| 32 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.50766722 |
| 33 | Purine metabolism_Homo sapiens_hsa00230 | 1.47585763 |
| 34 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.44849234 |
| 35 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.41817332 |
| 36 | Huntingtons disease_Homo sapiens_hsa05016 | 1.37161666 |
| 37 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.32705545 |
| 38 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.31906472 |
| 39 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.24157397 |
| 40 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.13053916 |
| 41 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.12932637 |
| 42 | Alzheimers disease_Homo sapiens_hsa05010 | 1.08179658 |
| 43 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.07585245 |
| 44 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.04621088 |
| 45 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.98025639 |
| 46 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.94549081 |
| 47 | Carbon metabolism_Homo sapiens_hsa01200 | 0.94534219 |
| 48 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.90983468 |
| 49 | Phototransduction_Homo sapiens_hsa04744 | 0.86835965 |
| 50 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.86534265 |
| 51 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.78336316 |
| 52 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.77498031 |
| 53 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.75788201 |
| 54 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.71476310 |
| 55 | Peroxisome_Homo sapiens_hsa04146 | 0.68080497 |
| 56 | Sulfur relay system_Homo sapiens_hsa04122 | 0.66848891 |
| 57 | Metabolic pathways_Homo sapiens_hsa01100 | 0.66420646 |
| 58 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.65899090 |
| 59 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.63191091 |
| 60 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.59752021 |
| 61 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.58377742 |
| 62 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.57975152 |
| 63 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.57140720 |
| 64 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.53091150 |
| 65 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.51190837 |
| 66 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.50686757 |
| 67 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.50495197 |
| 68 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.48924787 |
| 69 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.46677570 |
| 70 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.45754317 |
| 71 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.43146785 |
| 72 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.42637081 |
| 73 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.40620268 |
| 74 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.40084685 |
| 75 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.38381362 |
| 76 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.34433020 |
| 77 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.34223279 |
| 78 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.26572624 |
| 79 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.25609708 |
| 80 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.25196403 |
| 81 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.24403329 |
| 82 | Taste transduction_Homo sapiens_hsa04742 | 0.24151411 |
| 83 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.22162248 |
| 84 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.20039509 |
| 85 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.19560636 |
| 86 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.18875714 |
| 87 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.18485844 |
| 88 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.18384242 |
| 89 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.17752107 |
| 90 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.16971975 |
| 91 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.16577366 |
| 92 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.13481916 |
| 93 | Olfactory transduction_Homo sapiens_hsa04740 | 0.11154603 |
| 94 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.09862362 |
| 95 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.08795688 |
| 96 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.08687951 |
| 97 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.08642337 |
| 98 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.06065096 |
| 99 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.02827389 |
| 100 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.02422892 |

