PARP9

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)6.00900653
2antigen processing and presentation of endogenous peptide antigen (GO:0002483)6.00900653
3antigen processing and presentation of endogenous antigen (GO:0019883)5.54044281
4negative regulation of cell killing (GO:0031342)5.25044312
5negative regulation of leukocyte mediated cytotoxicity (GO:0001911)5.25044312
6antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.13257617
7response to type I interferon (GO:0034340)4.46890227
8cellular response to type I interferon (GO:0071357)4.45785393
9type I interferon signaling pathway (GO:0060337)4.45785393
10positive regulation of interferon-alpha production (GO:0032727)4.23124924
11detection of other organism (GO:0098543)4.18915639
12positive regulation of gamma-delta T cell activation (GO:0046645)4.16815392
13detection of molecule of bacterial origin (GO:0032490)4.14296069
14negative regulation of interleukin-12 production (GO:0032695)4.05028686
15regulation of interferon-alpha production (GO:0032647)4.00142231
16detection of bacterium (GO:0016045)3.96621292
17detection of external biotic stimulus (GO:0098581)3.89261703
18response to interferon-alpha (GO:0035455)3.72377786
19positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.67104795
20positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.57643612
21negative regulation of lymphocyte mediated immunity (GO:0002707)3.56706035
22negative regulation of T cell mediated immunity (GO:0002710)3.55371372
23microglial cell activation (GO:0001774)3.50067776
24positive regulation by symbiont of host defense response (GO:0052509)3.46083032
25modulation by symbiont of host defense response (GO:0052031)3.46083032
26modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.46083032
27modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.46083032
28positive regulation by organism of defense response of other organism involved in symbiotic interact3.46083032
29modulation by symbiont of host immune response (GO:0052553)3.46083032
30detection of biotic stimulus (GO:0009595)3.40817821
31positive regulation of natural killer cell differentiation (GO:0032825)3.40579758
32response to interleukin-15 (GO:0070672)3.37572603
33regulation of dendritic cell antigen processing and presentation (GO:0002604)3.35848820
34regulation of regulatory T cell differentiation (GO:0045589)3.33649363
35regulation of RIG-I signaling pathway (GO:0039535)3.32428555
36immunoglobulin mediated immune response (GO:0016064)3.29576854
37regulation of interferon-beta biosynthetic process (GO:0045357)3.26138516
38macrophage activation (GO:0042116)3.26034415
39neutrophil activation involved in immune response (GO:0002283)3.24948269
40response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.23066373
41response to host (GO:0075136)3.23066373
42response to host defenses (GO:0052200)3.23066373
43NIK/NF-kappaB signaling (GO:0038061)3.22609821
44cellular extravasation (GO:0045123)3.21470913
45production of molecular mediator involved in inflammatory response (GO:0002532)3.19509052
46negative regulation of viral genome replication (GO:0045071)3.17565895
47regulation of T cell tolerance induction (GO:0002664)3.17338928
48regulation of type I interferon-mediated signaling pathway (GO:0060338)3.16926510
49interferon-gamma-mediated signaling pathway (GO:0060333)3.15973224
50leukocyte aggregation (GO:0070486)3.13962592
51negative regulation of leukocyte mediated immunity (GO:0002704)3.13127968
52cellular response to interferon-beta (GO:0035458)3.12953221
53response to interferon-beta (GO:0035456)3.12100366
54cellular response to interleukin-15 (GO:0071350)3.11687741
55regulation of interleukin-12 biosynthetic process (GO:0045075)3.11087001
56regulation of gamma-delta T cell differentiation (GO:0045586)3.11031097
57positive regulation of interferon-beta production (GO:0032728)3.10490752
58positive regulation of heterotypic cell-cell adhesion (GO:0034116)3.09984834
59regulation of gamma-delta T cell activation (GO:0046643)3.09138230
60positive regulation of humoral immune response (GO:0002922)3.09102867
61response to peptidoglycan (GO:0032494)3.08791488
62triglyceride-rich lipoprotein particle remodeling (GO:0034370)3.04824459
63regulation of tolerance induction (GO:0002643)3.03611826
64negative T cell selection (GO:0043383)3.02642185
65negative thymic T cell selection (GO:0045060)3.02546397
66interferon-gamma secretion (GO:0072643)3.01332321
67antigen processing and presentation via MHC class Ib (GO:0002475)3.01186740
68positive regulation of type 2 immune response (GO:0002830)3.01108662
69regulation of T cell mediated cytotoxicity (GO:0001914)3.00368763
70response to interferon-gamma (GO:0034341)2.97817509
71regulation of antigen processing and presentation (GO:0002577)2.97646156
72JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.95286987
73germinal center formation (GO:0002467)2.93217672
74regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.91657612
75positive regulation of T cell mediated cytotoxicity (GO:0001916)2.90666607
76myeloid cell activation involved in immune response (GO:0002275)2.89578006
77complement activation, alternative pathway (GO:0006957)2.88106111
78neutrophil activation (GO:0042119)2.87080749
79negative regulation of innate immune response (GO:0045824)2.86090343
80cellular response to virus (GO:0098586)2.85668592
81regulation of cholesterol storage (GO:0010885)2.85343092
82positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.85271014
83phospholipid efflux (GO:0033700)2.84988154
84negative regulation of cytokine production involved in immune response (GO:0002719)2.82932641
85positive regulation of toll-like receptor signaling pathway (GO:0034123)2.82811448
86peptidyl-glutamic acid carboxylation (GO:0017187)2.81706722
87protein carboxylation (GO:0018214)2.81706722
88lipopolysaccharide-mediated signaling pathway (GO:0031663)2.81682736
89natural killer cell mediated cytotoxicity (GO:0042267)2.80231210
90natural killer cell mediated immunity (GO:0002228)2.80231210
91response to protozoan (GO:0001562)2.80023748
92B cell receptor signaling pathway (GO:0050853)2.78902347
93negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.78626010
94tolerance induction (GO:0002507)2.78625788
95macrophage activation involved in immune response (GO:0002281)2.77585236
96B cell mediated immunity (GO:0019724)2.77315649
97regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.77247073
98hydrogen peroxide biosynthetic process (GO:0050665)2.76680868
99positive regulation of antigen processing and presentation (GO:0002579)2.76360030
100positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.75848157
101plasma lipoprotein particle clearance (GO:0034381)2.75446000
102dendritic cell chemotaxis (GO:0002407)2.74832393
103low-density lipoprotein particle clearance (GO:0034383)2.74516333
104urea metabolic process (GO:0019627)2.74028368
105urea cycle (GO:0000050)2.74028368
106dendritic cell migration (GO:0036336)2.73257992
107regulation of alpha-beta T cell proliferation (GO:0046640)2.73042378
108negative regulation of lipid storage (GO:0010888)2.72471528
109regulation of natural killer cell differentiation (GO:0032823)2.72393514
110positive regulation of tolerance induction (GO:0002645)2.70918895
111cellular response to interferon-alpha (GO:0035457)2.69348074
112regulation of T-helper 1 cell differentiation (GO:0045625)2.68410611
113negative regulation of T-helper cell differentiation (GO:0045623)2.67952291
114negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.67952291
115T cell migration (GO:0072678)2.67861682
116tryptophan catabolic process (GO:0006569)2.67809221
117indole-containing compound catabolic process (GO:0042436)2.67809221
118indolalkylamine catabolic process (GO:0046218)2.67809221
119cellular response to exogenous dsRNA (GO:0071360)2.64581538
120respiratory burst (GO:0045730)2.64379865
121T-helper 1 type immune response (GO:0042088)2.63949050
122aromatic amino acid family catabolic process (GO:0009074)2.63189540
123positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.62289395
124fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)2.61696159
125defense response to protozoan (GO:0042832)2.60413178
126regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)2.60396009
127positive regulation of B cell differentiation (GO:0045579)2.59329659
128high-density lipoprotein particle remodeling (GO:0034375)2.57738731
129kynurenine metabolic process (GO:0070189)2.56377123
130tryptophan metabolic process (GO:0006568)2.56074733
131regulation of cholesterol esterification (GO:0010872)2.55761150
132erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.53310947
133L-phenylalanine catabolic process (GO:0006559)2.53310947
134regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.52957339
135alpha-linolenic acid metabolic process (GO:0036109)2.52912005
136acute-phase response (GO:0006953)2.52581821
137regulation of protein activation cascade (GO:2000257)2.52413758
138response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.52149381
139response to host immune response (GO:0052572)2.52149381
140granulocyte activation (GO:0036230)2.51560242
141positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.50803193
142cellular response to interferon-gamma (GO:0071346)2.50212486
143regulation of triglyceride catabolic process (GO:0010896)2.49216708
144positive regulation of interleukin-12 production (GO:0032735)2.48364325
145phospholipid homeostasis (GO:0055091)2.47861376
146reactive oxygen species biosynthetic process (GO:1903409)2.47550520
147regulation of interferon-gamma-mediated signaling pathway (GO:0060334)2.46691006
148* regulation of response to interferon-gamma (GO:0060330)2.46691006
149valine metabolic process (GO:0006573)2.46580358
150nitrogen cycle metabolic process (GO:0071941)2.46044415
151regulation of hypersensitivity (GO:0002883)2.45298607
152regulation of B cell receptor signaling pathway (GO:0050855)2.44821027
153defense response to virus (GO:0051607)2.42844840

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human6.57374609
2IRF8_21731497_ChIP-ChIP_J774_Mouse4.84345329
3* IRF1_21803131_ChIP-Seq_MONOCYTES_Human4.73559547
4ESR1_17901129_ChIP-ChIP_LIVER_Mouse4.55132094
5* IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.02660984
6FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.73591530
7* RXR_22158963_ChIP-Seq_LIVER_Mouse3.29735151
8EGR1_23403033_ChIP-Seq_LIVER_Mouse3.14781713
9IRF8_27001747_Chip-Seq_BMDM_Mouse3.09387289
10SMAD_19615063_ChIP-ChIP_OVARY_Human3.08269477
11PPARA_22158963_ChIP-Seq_LIVER_Mouse3.07785778
12STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.01315218
13SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.86637045
14NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.82047297
15BP1_19119308_ChIP-ChIP_Hs578T_Human2.77241199
16* LXR_22158963_ChIP-Seq_LIVER_Mouse2.68580513
17PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.61744634
18MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.57485471
19RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.55860787
20MYB_21317192_ChIP-Seq_ERMYB_Mouse2.42554838
21STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.41649599
22* STAT4_19710469_ChIP-ChIP_TH1__Mouse2.41199927
23EGR1_19374776_ChIP-ChIP_THP-1_Human2.40587668
24STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse2.27839050
25STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.27737070
26CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.26313838
27NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.24914701
28SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.21999629
29GATA1_22025678_ChIP-Seq_K562_Human2.21059369
30Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.18589115
31NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.98034397
32FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.94517275
33BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.82636400
34MYB_26560356_Chip-Seq_TH2_Human1.80009797
35BRD4_27068464_Chip-Seq_AML-cells_Mouse1.77302757
36MAF_26560356_Chip-Seq_TH1_Human1.72990141
37* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.66104914
38TP63_17297297_ChIP-ChIP_HaCaT_Human1.65777688
39CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.63668083
40RUNX_20019798_ChIP-Seq_JUKART_Human1.63604064
41MYB_26560356_Chip-Seq_TH1_Human1.62127779
42SPI1_23547873_ChIP-Seq_NB4_Human1.61071929
43RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.57279706
44SCL_19346495_ChIP-Seq_HPC-7_Human1.55732596
45VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.50948623
46RUNX1_22412390_ChIP-Seq_EML_Mouse1.36223925
47PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.35852789
48ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.34996853
49SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.33706958
50PU_27001747_Chip-Seq_BMDM_Mouse1.33211765
51THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.30936860
52VDR_24763502_ChIP-Seq_THP-1_Human1.29640033
53NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.28834811
54CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.28058160
55VDR_21846776_ChIP-Seq_THP-1_Human1.27479916
56CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.26675482
57UTX_26944678_Chip-Seq_JUKART_Human1.26528697
58CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.25092523
59GATA2_22383799_ChIP-Seq_G1ME_Mouse1.24260664
60TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.23009113
61E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.17266768
62CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.17103024
63GATA3_27048872_Chip-Seq_THYMUS_Human1.17075201
64* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.14820403
65MYC_22102868_ChIP-Seq_BL_Human1.14516708
66TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.13735837
67CLOCK_20551151_ChIP-Seq_293T_Human1.11532588
68GATA2_21666600_ChIP-Seq_HMVEC_Human1.07578076
69SPI1_23127762_ChIP-Seq_K562_Human1.06758827
70NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.05411577
71GATA3_26560356_Chip-Seq_TH2_Human1.04475763
72MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.00776198
73MAF_26560356_Chip-Seq_TH2_Human1.00435436
74CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.00282772
75LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.98560104
76CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.96521367
77PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.96420825
78HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.96338381
79GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.95388307
80TCF7_22412390_ChIP-Seq_EML_Mouse0.95018383
81VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.95007507
82BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.94609671
83TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.94605067
84GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.93215073
85FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.91839710
86GATA1_19941826_ChIP-Seq_K562_Human0.90803766
87ELK3_25401928_ChIP-Seq_HUVEC_Human0.89887138
88RARG_19884340_ChIP-ChIP_MEFs_Mouse0.88861493
89GATA1_22383799_ChIP-Seq_G1ME_Mouse0.88380339
90PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.87196467
91VDR_24787735_ChIP-Seq_THP-1_Human0.87047303
92NOTCH1_21737748_ChIP-Seq_TLL_Human0.86620115
93SMRT_27268052_Chip-Seq_Bcells_Human0.85623918
94RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.85537479
95ESR1_20079471_ChIP-ChIP_T-47D_Human0.84714674
96ELF1_17652178_ChIP-ChIP_JURKAT_Human0.84554655
97FOXO3_23340844_ChIP-Seq_DLD1_Human0.83643802
98TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.82979859
99PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.82518597
100SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.82099435
101KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.81833193
102TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.81576166
103GATA1_19941827_ChIP-Seq_MEL_Mouse0.81416944
104SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.80846678
105STAT3_1855785_ChIP-Seq_MESCs_Mouse0.80556536
106KDM2B_26808549_Chip-Seq_SUP-B15_Human0.79212768
107LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.78742587
108GATA4_25053715_ChIP-Seq_YYC3_Human0.77523586
109EGR1_19032775_ChIP-ChIP_M12_Human0.76341249
110SOX2_27498859_Chip-Seq_STOMACH_Mouse0.75510118
111KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.75038930
112* SOX2_20726797_ChIP-Seq_SW620_Human0.74983586
113GATA2_19941826_ChIP-Seq_K562_Human0.74565190
114E2F7_22180533_ChIP-Seq_HELA_Human0.71886532
115FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.71139712
116EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.66603307
117GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.65516553
118CDX2_19796622_ChIP-Seq_MESCs_Mouse0.65379594
119GATA1_19941827_ChIP-Seq_MEL86_Mouse0.64934114
120FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.64904068
121STAT1_20625510_ChIP-Seq_HELA_Human0.63973888
122JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.63355427
123KDM2B_26808549_Chip-Seq_DND41_Human0.62831032

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation3.72046565
2MP0009785_altered_susceptibility_to3.18346754
3MP0002139_abnormal_hepatobiliary_system3.15314159
4MP0005360_urolithiasis3.10095012
5MP0003436_decreased_susceptibility_to2.81737659
6MP0000685_abnormal_immune_system2.78318574
7MP0003724_increased_susceptibility_to2.69171428
8MP0005025_abnormal_response_to2.46719733
9MP0001790_abnormal_immune_system2.44607953
10MP0005387_immune_system_phenotype2.44607953
11MP0003191_abnormal_cellular_cholesterol2.38757704
12MP0009840_abnormal_foam_cell2.38659710
13MP0005000_abnormal_immune_tolerance2.33828098
14MP0002148_abnormal_hypersensitivity_rea2.31457410
15MP0005671_abnormal_response_to2.31256850
16MP0006082_CNS_inflammation2.30906420
17MP0005365_abnormal_bile_salt2.27589331
18MP0005085_abnormal_gallbladder_physiolo2.27470693
19MP0001800_abnormal_humoral_immune2.25863306
20MP0002419_abnormal_innate_immunity2.23456766
21MP0003303_peritoneal_inflammation2.09743426
22MP0002452_abnormal_antigen_presenting2.08383203
23MP0002723_abnormal_immune_serum2.06551126
24MP0002166_altered_tumor_susceptibility1.99953582
25MP0004947_skin_inflammation1.92026900
26MP0002138_abnormal_hepatobiliary_system1.89448745
27MP0008875_abnormal_xenobiotic_pharmacok1.87143754
28MP0005464_abnormal_platelet_physiology1.85416173
29MP0002006_tumorigenesis1.84694618
30MP0001819_abnormal_immune_cell1.82379254
31MP0002420_abnormal_adaptive_immunity1.80065167
32MP0001853_heart_inflammation1.74394752
33MP0008469_abnormal_protein_level1.74231339
34MP0009764_decreased_sensitivity_to1.73145430
35MP0003252_abnormal_bile_duct1.70534784
36MP0010155_abnormal_intestine_physiology1.66520266
37MP0004510_myositis1.66125133
38MP0001845_abnormal_inflammatory_respons1.65640928
39MP0005058_abnormal_lysosome_morphology1.63225682
40MP0010329_abnormal_lipoprotein_level1.57320833
41MP0003300_gastrointestinal_ulcer1.57050044
42MP0003763_abnormal_thymus_physiology1.54069534
43MP0001533_abnormal_skeleton_physiology1.51521075
44MP0003045_fibrosis1.48177675
45MP0000609_abnormal_liver_physiology1.46635578
46MP0002405_respiratory_system_inflammati1.45600429
47MP0000716_abnormal_immune_system1.45050272
48MP0002398_abnormal_bone_marrow1.42490534
49MP0002254_reproductive_system_inflammat1.36508814
50MP0005083_abnormal_biliary_tract1.34078853
51MP0003806_abnormal_nucleotide_metabolis1.33919355
52MP0000569_abnormal_digit_pigmentation1.32013786
53MP0005397_hematopoietic_system_phenotyp1.30520228
54MP0001545_abnormal_hematopoietic_system1.30520228
55MP0009763_increased_sensitivity_to1.29438209
56MP0003186_abnormal_redox_activity1.27555248
57MP0000689_abnormal_spleen_morphology1.25786734
58MP0004883_abnormal_blood_vessel1.24177596
59MP0009333_abnormal_splenocyte_physiolog1.22896315
60MP0003448_altered_tumor_morphology1.22187113
61MP0008260_abnormal_autophagy1.20228085
62MP0003705_abnormal_hypodermis_morpholog1.19926601
63MP0005319_abnormal_enzyme/_coenzyme1.19734491
64MP0002429_abnormal_blood_cell1.19159464
65MP0002722_abnormal_immune_system1.18347816
66MP0003183_abnormal_peptide_metabolism1.17573649
67MP0005164_abnormal_response_to1.17269499
68MP0009278_abnormal_bone_marrow1.15700073
69MP0002277_abnormal_respiratory_mucosa1.15467057
70MP0001666_abnormal_nutrient_absorption1.15407252
71MP0000858_altered_metastatic_potential1.14288670
72MP0010352_gastrointestinal_tract_polyps1.08707021
73MP0005310_abnormal_salivary_gland1.05663895
74MP0004381_abnormal_hair_follicle1.04612107
75MP0000343_altered_response_to1.02082182
76MP0004782_abnormal_surfactant_physiolog1.01287745
77MP0005332_abnormal_amino_acid1.00613433
78MP0003075_altered_response_to1.00602915
79MP0005075_abnormal_melanosome_morpholog1.00272738
80MP0003453_abnormal_keratinocyte_physiol1.00035946
81MP0003195_calcinosis0.99062123
82MP0001873_stomach_inflammation0.98379456
83MP0003690_abnormal_glial_cell0.98255313
84MP0010234_abnormal_vibrissa_follicle0.97999856
85MP0000604_amyloidosis0.97924083
86MP0001851_eye_inflammation0.97650833
87MP0002998_abnormal_bone_remodeling0.95355881
88MP0006054_spinal_hemorrhage0.94450483
89MP0003656_abnormal_erythrocyte_physiolo0.93411807
90MP0002118_abnormal_lipid_homeostasis0.92417035
91MP0000598_abnormal_liver_morphology0.91962313
92MP0003172_abnormal_lysosome_physiology0.91807403
93MP0009643_abnormal_urine_homeostasis0.91678650
94MP0003828_pulmonary_edema0.91590311
95MP0005584_abnormal_enzyme/coenzyme_acti0.91393518
96MP0002132_abnormal_respiratory_system0.88790404
97MP0005166_decreased_susceptibility_to0.87465981
98MP0010307_abnormal_tumor_latency0.87338679
99MP0002396_abnormal_hematopoietic_system0.86464483
100MP0002136_abnormal_kidney_physiology0.81562461
101MP0002332_abnormal_exercise_endurance0.80928411
102MP0005023_abnormal_wound_healing0.80652921
103MP0009765_abnormal_xenobiotic_induced0.80395525
104MP0002693_abnormal_pancreas_physiology0.80015147
105MP0004019_abnormal_vitamin_homeostasis0.79960786
106MP0004808_abnormal_hematopoietic_stem0.78291473
107MP0003566_abnormal_cell_adhesion0.77942841
108MP0005167_abnormal_blood-brain_barrier0.77677476
109MP0002933_joint_inflammation0.77488544
110MP0003866_abnormal_defecation0.74780919
111MP0000249_abnormal_blood_vessel0.74482804
112MP0001663_abnormal_digestive_system0.73672323
113MP0005390_skeleton_phenotype0.73463123
114MP0003091_abnormal_cell_migration0.73131688
115MP0005451_abnormal_body_composition0.72580624
116MP0001764_abnormal_homeostasis0.71188134
117MP0000015_abnormal_ear_pigmentation0.71035039
118MP0001881_abnormal_mammary_gland0.70584583
119MP0000703_abnormal_thymus_morphology0.69998330
120MP0002168_other_aberrant_phenotype0.69969703
121MP0000465_gastrointestinal_hemorrhage0.68092202
122MP0008004_abnormal_stomach_pH0.65444242
123MP0003795_abnormal_bone_structure0.65175674
124MP0000371_diluted_coat_color0.64905616

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)4.88266794
2Recurrent gram-negative bacterial infections (HP:0005420)4.48760203
3Autoimmune thrombocytopenia (HP:0001973)4.32221276
4Recurrent abscess formation (HP:0002722)4.29729103
5Elevated erythrocyte sedimentation rate (HP:0003565)4.13410817
6Recurrent bacterial skin infections (HP:0005406)4.11449230
7Systemic lupus erythematosus (HP:0002725)3.74549594
8Chronic otitis media (HP:0000389)3.58359529
9Myositis (HP:0100614)3.43165807
10Keratoconjunctivitis (HP:0001096)3.37501029
11Joint hemorrhage (HP:0005261)3.35237223
12Deep venous thrombosis (HP:0002625)3.34130655
13Recurrent viral infections (HP:0004429)3.33416524
14Recurrent fungal infections (HP:0002841)3.26941018
15Mediastinal lymphadenopathy (HP:0100721)3.21508790
16Abnormality of macrophages (HP:0004311)3.21410947
17Xanthomatosis (HP:0000991)3.20841475
18Complement deficiency (HP:0004431)3.19019919
19Encephalitis (HP:0002383)3.16629271
20Orchitis (HP:0100796)3.14099973
21Vasculitis (HP:0002633)3.13863367
22Abnormality of monocarboxylic acid metabolism (HP:0010996)3.11634140
23Recurrent skin infections (HP:0001581)3.10996688
24Prolonged partial thromboplastin time (HP:0003645)3.09099864
25Intrahepatic cholestasis (HP:0001406)3.06354513
26Gingival bleeding (HP:0000225)3.02895069
27Myocardial infarction (HP:0001658)3.02337114
28Abnormality of aromatic amino acid family metabolism (HP:0004338)2.99479921
29Abnormality of the common coagulation pathway (HP:0010990)2.98303039
30Nasal polyposis (HP:0100582)2.96697730
31Recurrent bronchitis (HP:0002837)2.89723697
32Increased IgM level (HP:0003496)2.86727466
33Abnormality of the nasal mucosa (HP:0000433)2.83864338
34Optic neuritis (HP:0100653)2.76908256
35Retrobulbar optic neuritis (HP:0100654)2.76908256
36Hypobetalipoproteinemia (HP:0003563)2.74042279
37Abnormality of T cell number (HP:0011839)2.72419172
38Stomatitis (HP:0010280)2.72029913
39Vacuolated lymphocytes (HP:0001922)2.71740115
40Pustule (HP:0200039)2.69710537
41Gingivitis (HP:0000230)2.69247227
42Chest pain (HP:0100749)2.67723270
43Periodontitis (HP:0000704)2.63135822
44Abnormality of complement system (HP:0005339)2.61232294
45Interstitial pulmonary disease (HP:0006530)2.60034973
46Autoimmune hemolytic anemia (HP:0001890)2.59113872
47Inflammation of the large intestine (HP:0002037)2.56713454
48Abnormality of glutamine family amino acid metabolism (HP:0010902)2.55638459
49Gastrointestinal infarctions (HP:0005244)2.54990795
50Gangrene (HP:0100758)2.54267697
51Peritonitis (HP:0002586)2.53606785
52Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.51128936
53Recurrent cutaneous fungal infections (HP:0011370)2.49777375
54Chronic mucocutaneous candidiasis (HP:0002728)2.49777375
55Joint swelling (HP:0001386)2.49203963
56Prolonged bleeding time (HP:0003010)2.47674756
57T lymphocytopenia (HP:0005403)2.47075241
58Spontaneous hematomas (HP:0007420)2.45684039
59Chronic diarrhea (HP:0002028)2.45416069
60Arterial thrombosis (HP:0004420)2.44938665
61Abnormality of liposaccharide metabolism (HP:0010968)2.44474319
62Abnormality of glycosphingolipid metabolism (HP:0004343)2.44474319
63Abnormality of glycolipid metabolism (HP:0010969)2.44474319
64Loss of speech (HP:0002371)2.43281705
65Gastrointestinal inflammation (HP:0004386)2.43216806
66Esophageal varix (HP:0002040)2.42455181
67Hypergammaglobulinemia (HP:0010702)2.41694125
68Hyperlipoproteinemia (HP:0010980)2.40561202
69Glomerulonephritis (HP:0000099)2.39284258
70Tetraparesis (HP:0002273)2.38314682
71Nephritis (HP:0000123)2.38252643
72Pulmonary infiltrates (HP:0002113)2.37927545
73Abnormality of T cells (HP:0002843)2.37489469
74Epistaxis (HP:0000421)2.37056482
75Epidermoid cyst (HP:0200040)2.36930031
76Basal ganglia calcification (HP:0002135)2.36336465
77Abnormality of T cell physiology (HP:0011840)2.35529242
78Abnormality of the pleura (HP:0002103)2.34631723
79Cellulitis (HP:0100658)2.33969324
80Urticaria (HP:0001025)2.32210725
81Hematochezia (HP:0002573)2.31307783
82Meningitis (HP:0001287)2.29449972
83Thrombophlebitis (HP:0004418)2.26951520
84Malnutrition (HP:0004395)2.26854081
85Hypochromic microcytic anemia (HP:0004840)2.23632883
86Hypochromic anemia (HP:0001931)2.23260509
87Colitis (HP:0002583)2.22355818
88Eosinophilia (HP:0001880)2.22251976
89Abnormal delayed hypersensitivity skin test (HP:0002963)2.22166139
90Pulmonary embolism (HP:0002204)2.21495427
91Leukocytosis (HP:0001974)2.20146894
92IgG deficiency (HP:0004315)2.19174686
93Cheilitis (HP:0100825)2.19069402
94Hemoptysis (HP:0002105)2.18810508
95Panhypogammaglobulinemia (HP:0003139)2.18655668
96Episodic fever (HP:0001954)2.18530383
97Hypercholesterolemia (HP:0003124)2.17573621
98Hemorrhage of the eye (HP:0011885)2.15247209
99Keratoconjunctivitis sicca (HP:0001097)2.13291095
100Thrombocytosis (HP:0001894)2.13113484
101Acne (HP:0001061)2.12680913
102Fat malabsorption (HP:0002630)2.12302378
103Abnormality of the intrinsic pathway (HP:0010989)2.11115158
104Osteomyelitis (HP:0002754)2.09922093
105IgA deficiency (HP:0002720)2.09537714
106Abnormality of the endocardium (HP:0004306)2.08768521
107Anorexia (HP:0002039)2.08215636
108Hypolipoproteinemia (HP:0010981)2.07560012
109Purpura (HP:0000979)2.06659157
110Abnormality of eosinophils (HP:0001879)2.05478391
111Acute hepatic failure (HP:0006554)2.04733000
112IgM deficiency (HP:0002850)2.04405422
113Menorrhagia (HP:0000132)2.04258082
114Premature loss of primary teeth (HP:0006323)2.04049322
115Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.03823804
116Amyloidosis (HP:0011034)2.03537684
117Hyperammonemia (HP:0001987)2.03361889
118Increased IgE level (HP:0003212)2.02383282
119Axonal loss (HP:0003447)2.02222948
120Granulocytopenia (HP:0001913)2.02112548
121Abnormality of sulfur amino acid metabolism (HP:0004339)2.01756963
122Abnormality of iron homeostasis (HP:0011031)2.01665598
123Chronic obstructive pulmonary disease (HP:0006510)2.00903107
124Obstructive lung disease (HP:0006536)2.00903107
125Agammaglobulinemia (HP:0004432)2.00643561
126Petechiae (HP:0000967)1.99354011
127Abnormality of the pericardium (HP:0001697)1.98954510
128Lymphopenia (HP:0001888)1.98873801
129Increased CSF protein (HP:0002922)1.98714882
130Abnormality of cells of the lymphoid lineage (HP:0012140)1.98180426
131Increased serum ferritin (HP:0003281)1.98112476
132Osteolytic defects of the hand bones (HP:0009699)1.97872910
133Osteolytic defects of the phalanges of the hand (HP:0009771)1.97872910
134Dysostosis multiplex (HP:0000943)1.95191021
135Gastrointestinal stroma tumor (HP:0100723)1.94272677
136Keratitis (HP:0000491)1.93703436
137Increased cerebral lipofuscin (HP:0011813)1.91338447
138Glomerulopathy (HP:0100820)1.89372226
139Microcytic anemia (HP:0001935)1.89177262

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TYK23.74383564
2MAP3K143.62935807
3MAP4K13.39346175
4TBK13.23955230
5FGFR43.22226767
6JAK33.05992172
7IKBKE2.97647289
8ERN12.64147874
9TXK2.56513693
10JAK12.55218874
11MAP3K102.32839641
12KIT2.30093311
13IRAK32.13060760
14BLK2.09892436
15IRAK42.08682417
16IKBKB1.95817096
17ZAP701.87155440
18FGFR31.74177266
19MAP3K131.65747312
20FLT31.63642715
21RIPK41.51499879
22PKN21.50252383
23TAOK31.49884620
24FGR1.43948328
25EPHB11.43889437
26TNK21.43420217
27CSK1.42592384
28SIK11.40212248
29PBK1.38926905
30EPHA31.33685777
31NEK91.33027770
32PRPF4B1.32509097
33CHUK1.29839806
34JAK21.29723062
35NME21.29624506
36TRIB31.28202890
37CSF1R1.27703917
38SYK1.27628526
39BTK1.25432144
40RPS6KA41.21576242
41STK101.20870225
42TGFBR21.20529779
43MAP3K21.18989158
44MAP2K31.18275731
45TAOK11.15177911
46HCK1.15017528
47MST41.14003105
48LCK1.11371621
49TEC1.09372062
50NLK1.03937013
51PTK61.02680976
52HIPK21.02256914
53ITK1.02189122
54MAP3K31.02033654
55PIM21.00122481
56BCKDK0.98963035
57GRK70.96987810
58LRRK20.96390859
59PIM10.95938344
60KDR0.95351056
61GRK60.90142849
62MAPK110.88499725
63CDC42BPA0.88260283
64LYN0.84542823
65MST1R0.82293490
66STK40.81873410
67YES10.81720841
68IRAK20.80925014
69RIPK10.79365805
70IRAK10.78273658
71PTK2B0.75844483
72MAP2K60.74298053
73CDK60.73621474
74MAP3K110.71936835
75MARK30.68419876
76TRPM70.66513256
77TTN0.62679420
78STK30.60680715
79CAMKK20.59843584
80MAP3K50.59590605
81MATK0.58226213
82SIK30.57107598
83FRK0.56889171
84PDPK10.56815106
85MAPK70.53055715
86FER0.52787752
87BMX0.52246325
88PRKD20.51384455
89KSR20.50835717
90CDK40.50640696
91PIK3CG0.49884402
92ABL20.48933084
93ABL10.48407091
94MAP3K60.47852123
95EGFR0.47132014
96TGFBR10.46698652
97PRKCQ0.46385092
98TAOK20.46304967
99EEF2K0.46251502
100EIF2AK20.45663563
101DAPK20.45231230
102ADRBK20.40279505
103FYN0.38926405
104MELK0.38625380
105PRKCD0.38427674
106CAMK1D0.38310294
107RET0.36498021
108MAP3K10.36247692
109STK240.35494352
110FES0.32904158
111STK380.32546431
112ACVR1B0.32269769
113IGF1R0.32015780
114SGK30.31111766
115MAPK120.30594936
116MARK20.30255978
117MAP3K120.28901496
118CDK120.28884520
119DYRK1B0.28878488
120PRKG20.28237975
121PDK10.27863613
122MAPKAPK20.27487607
123MAPKAPK30.27264640
124NUAK10.27195535
125STK110.27162105
126MAP3K80.27048751
127MAPK40.25793940
128INSRR0.25621360
129MAP2K20.25368833
130BMPR20.24475222
131MAP3K70.23790629
132TIE10.23579391
133PRKAA20.23394320
134PDGFRB0.20997037
135RPS6KA60.20803085

Predicted pathways (KEGG)

RankGene SetZ-score
1Staphylococcus aureus infection_Homo sapiens_hsa051503.00440591
2Primary bile acid biosynthesis_Homo sapiens_hsa001202.64669222
3Caffeine metabolism_Homo sapiens_hsa002322.43218558
4Leishmaniasis_Homo sapiens_hsa051402.34370057
5NF-kappa B signaling pathway_Homo sapiens_hsa040642.20370927
6Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.19394446
7Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.17506109
8Complement and coagulation cascades_Homo sapiens_hsa046102.13908698
9Graft-versus-host disease_Homo sapiens_hsa053322.11523766
10Toll-like receptor signaling pathway_Homo sapiens_hsa046202.07742563
11Measles_Homo sapiens_hsa051622.04460468
12RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.00339431
13Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.00254720
14Allograft rejection_Homo sapiens_hsa053301.99308915
15Intestinal immune network for IgA production_Homo sapiens_hsa046721.94593122
16Primary immunodeficiency_Homo sapiens_hsa053401.85054080
17Pentose and glucuronate interconversions_Homo sapiens_hsa000401.83136065
18Arginine biosynthesis_Homo sapiens_hsa002201.75066594
19Nitrogen metabolism_Homo sapiens_hsa009101.68524099
20Osteoclast differentiation_Homo sapiens_hsa043801.68258278
21Legionellosis_Homo sapiens_hsa051341.65641573
22Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.65504036
23Influenza A_Homo sapiens_hsa051641.56625820
24Pertussis_Homo sapiens_hsa051331.52363115
25Tryptophan metabolism_Homo sapiens_hsa003801.48957675
26NOD-like receptor signaling pathway_Homo sapiens_hsa046211.46141676
27Herpes simplex infection_Homo sapiens_hsa051681.41253361
28Fatty acid degradation_Homo sapiens_hsa000711.41167915
29Antigen processing and presentation_Homo sapiens_hsa046121.38212044
30Malaria_Homo sapiens_hsa051441.36794183
31TNF signaling pathway_Homo sapiens_hsa046681.35687500
32Toxoplasmosis_Homo sapiens_hsa051451.27736166
33PPAR signaling pathway_Homo sapiens_hsa033201.27247462
34Peroxisome_Homo sapiens_hsa041461.25225422
35Jak-STAT signaling pathway_Homo sapiens_hsa046301.17611699
36Tuberculosis_Homo sapiens_hsa051521.16921644
37B cell receptor signaling pathway_Homo sapiens_hsa046621.15635805
38Drug metabolism - other enzymes_Homo sapiens_hsa009831.10546081
39Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.05877573
40Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.05555228
41Hematopoietic cell lineage_Homo sapiens_hsa046401.04621406
42Hepatitis C_Homo sapiens_hsa051601.04091268
43Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.03601991
44Histidine metabolism_Homo sapiens_hsa003401.03525702
45Autoimmune thyroid disease_Homo sapiens_hsa053201.03416045
46Apoptosis_Homo sapiens_hsa042101.02479024
47African trypanosomiasis_Homo sapiens_hsa051431.01965938
48Chemical carcinogenesis_Homo sapiens_hsa052041.01860874
49Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.95845301
50ABC transporters_Homo sapiens_hsa020100.95688091
51Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.94567636
52Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.92436316
53Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.92061700
54Asthma_Homo sapiens_hsa053100.87902080
55Type I diabetes mellitus_Homo sapiens_hsa049400.87717929
56Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.85256419
57Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.83930433
58Hepatitis B_Homo sapiens_hsa051610.83681749
59Steroid hormone biosynthesis_Homo sapiens_hsa001400.83609057
60Retinol metabolism_Homo sapiens_hsa008300.82943997
61Rheumatoid arthritis_Homo sapiens_hsa053230.82050490
62Selenocompound metabolism_Homo sapiens_hsa004500.81935321
63Starch and sucrose metabolism_Homo sapiens_hsa005000.81730295
64SNARE interactions in vesicular transport_Homo sapiens_hsa041300.80309492
65Adipocytokine signaling pathway_Homo sapiens_hsa049200.79889099
66Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.79580955
67T cell receptor signaling pathway_Homo sapiens_hsa046600.79406027
68Sulfur relay system_Homo sapiens_hsa041220.79077328
69Folate biosynthesis_Homo sapiens_hsa007900.78744716
70Platelet activation_Homo sapiens_hsa046110.78173048
71Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.77994385
72beta-Alanine metabolism_Homo sapiens_hsa004100.77606289
73Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.77523702
74Dorso-ventral axis formation_Homo sapiens_hsa043200.75446649
75Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.73601370
76Phenylalanine metabolism_Homo sapiens_hsa003600.72944413
77Lysosome_Homo sapiens_hsa041420.72361820
78Viral myocarditis_Homo sapiens_hsa054160.68389367
79Fatty acid metabolism_Homo sapiens_hsa012120.67530155
80Chemokine signaling pathway_Homo sapiens_hsa040620.67059729
81Acute myeloid leukemia_Homo sapiens_hsa052210.66835164
82Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.65381537
83Fat digestion and absorption_Homo sapiens_hsa049750.63557872
84Salmonella infection_Homo sapiens_hsa051320.63401225
85Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.61986462
86Non-small cell lung cancer_Homo sapiens_hsa052230.60372901
87Shigellosis_Homo sapiens_hsa051310.60244603
88Leukocyte transendothelial migration_Homo sapiens_hsa046700.58887142
89Glycosaminoglycan degradation_Homo sapiens_hsa005310.57284518
90Vitamin digestion and absorption_Homo sapiens_hsa049770.57246064
91Propanoate metabolism_Homo sapiens_hsa006400.56079175
92Carbohydrate digestion and absorption_Homo sapiens_hsa049730.54056536
93Insulin resistance_Homo sapiens_hsa049310.54021924
94Sphingolipid signaling pathway_Homo sapiens_hsa040710.53949577
95AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.52427397
96Pentose phosphate pathway_Homo sapiens_hsa000300.51809952
97Prolactin signaling pathway_Homo sapiens_hsa049170.51246519
98VEGF signaling pathway_Homo sapiens_hsa043700.51045395
99Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.50390975
100Bile secretion_Homo sapiens_hsa049760.48860876
101Epstein-Barr virus infection_Homo sapiens_hsa051690.47563585
102Phagosome_Homo sapiens_hsa041450.46679680
103FoxO signaling pathway_Homo sapiens_hsa040680.45979927
104Prion diseases_Homo sapiens_hsa050200.45271391
105Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.44071079
106Amoebiasis_Homo sapiens_hsa051460.43748509
107Type II diabetes mellitus_Homo sapiens_hsa049300.42047171
108One carbon pool by folate_Homo sapiens_hsa006700.41948252
109Other glycan degradation_Homo sapiens_hsa005110.41157103
110Pancreatic cancer_Homo sapiens_hsa052120.40337302
111Tyrosine metabolism_Homo sapiens_hsa003500.40049996
112Small cell lung cancer_Homo sapiens_hsa052220.39981382
113Neurotrophin signaling pathway_Homo sapiens_hsa047220.37873854
114Renal cell carcinoma_Homo sapiens_hsa052110.35290031
115Chronic myeloid leukemia_Homo sapiens_hsa052200.34603208
116Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.34396586
117Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.34250492
118Endocytosis_Homo sapiens_hsa041440.34244755
119mTOR signaling pathway_Homo sapiens_hsa041500.34178251
120Viral carcinogenesis_Homo sapiens_hsa052030.32686440
121Arachidonic acid metabolism_Homo sapiens_hsa005900.32213192
122Maturity onset diabetes of the young_Homo sapiens_hsa049500.29467353
123GnRH signaling pathway_Homo sapiens_hsa049120.28798869
124Transcriptional misregulation in cancer_Homo sapiens_hsa052020.28666076
125Phosphatidylinositol signaling system_Homo sapiens_hsa040700.28008936
126Sphingolipid metabolism_Homo sapiens_hsa006000.26977041
127HTLV-I infection_Homo sapiens_hsa051660.26293273
128HIF-1 signaling pathway_Homo sapiens_hsa040660.25715851
129Inositol phosphate metabolism_Homo sapiens_hsa005620.24558560
130Phospholipase D signaling pathway_Homo sapiens_hsa040720.24503883
131Glycerophospholipid metabolism_Homo sapiens_hsa005640.23674429
132Regulation of autophagy_Homo sapiens_hsa041400.23487040
133Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.21486834
134Choline metabolism in cancer_Homo sapiens_hsa052310.19638662
135Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.18664058

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »